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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-03-07
    Beschreibung: This reprint is the printed edition of the Special Issue published in Materials. The reprint provides an overview on current international research activities in the field of advanced pulse laser machining technology. It covers fundamental and applied aspects and collects contributions of renowned scientists from academics and industries working in the fields of laser processing, materials science, physics, chemistry, and engineering in order to foster the current knowledge and present new ideas for future applications and new technologies.
    Schlagwort(e): multi-beam micromachining ; beam splitting ; invar ; shadow masks ; OLED ; nanosecond laser ; direct laser interference patterning ; design of experiments ; central composite design ; morphological filtering ; surface texture homogeneity ; micro structuring ; bearing steel ; dual laser beam processing ; excited state absorption ; semiconducting thin films ; stimulated emission depletion ; femtosecond laser ; silicon ; amorphization ; crystallization ; spectroscopic imaging ellipsometry ; transmission electron microscopy ; atomic force microscopy ; laser ablation ; ultrafast ; re-deposition ; fs-laser writing ; waveguides ; element redistribution ; Soret effect ; diffusion competition effects ; ultra-short pulses ; double pulses ; burst processing ; MHz bursts ; GHz bursts ; X-ray emission ; micromachining ; dose rate ; X-ray spectrum ; ultrafast laser ; laser ; ultrashort pulse ; plasma ; X-ray ; Bremsstrahlung ; resonance absorption ; burst ; bi-burst ; beam shaping ; squared top-hat ; fs-laser ; laser surface structuring ; laser-induced periodic surface structures ; micro-channels ; glass ; ultrafast laser processing ; Bessel beam ; X-ray emission hazards ; ultrashort pulsed laser ; radiation protection ; industrial applications ; protection housing ; ambient dose rate ; pulsed laser ; laser micromachining ; mechanical shutter ; solenoid shutter ; electro-optic modulator shutter ; opening time ; lifetime ; X-ray energies ; X-ray dose rate ; laser printing ; laser-induced forward transfer (LIFT) ; digital manufacturing ; additive manufacturing ; printing of materials ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
    Sprache: Englisch
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  • 2
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-01-08
    Beschreibung: Global warming is imposing tremendous challenges upon human and otherwise biotic life on Earth. A warmer atmosphere holds more moisture. The consensus is that the moisture transport by the atmospheric circulation strengthens and makes already wet areas of moisture convergence wetter and already dry areas of moisture divergence drier. Therefore, the tropics and mid-to-high latitudes will get wetter and the subtropics will get drier. Without any change in the interannual variability of hydroclimate, the change in the mean hydroclimate would equally increase drought risk in some places and flood risk in others. Moreover, global warming will cause the interannual variability of the hydroclimate to intensify, which will induce more droughts and floods. Furthermore, the changing atmospheric circulation interaction with the land surface may cause storm track alterations and may play an important role in shaping moisture redistribution. The author's contributions have documented the precipitation trends in southeast of the US, the Nile River Basin Ethiopia, Iraq, the Huai River Basin of northern China, and the Qilian Mountains of western China. The precipitation predictability on both global and regional scales are also studied. The interaction among climate systems in southeast Asia is also explicitly documented.
    Schlagwort(e): El Niño ; winter weather types ; precipitable water ; surface water vapor pressure ; consistency ; interannual and long-term trend ; precipitation ; trend analysis ; Iraq ; climate projection ; CMIP5 ; groundwater levels ; rainfall ; temperature ; Mann–Kendall test ; Bayesian Ensemble Algorithm ; rainstorm process ; rainstorm intensity ; risk estimation and mapping ; CMIP6 ; risk prediction ; Southwest China ; rainstorm and flood ; spatial and temporal change ; atmospheric circulation ; rainfall change ; CHIRPS ; PERSIANN-CDR ; descriptive statistics ; non-parametric trends ; Google Earth Engine ; central Punjab ; climate change ; land cover/land use ; vegetation ; NDVI ; Huai River Basin ; trends and variability ; flood magnitude ; Qilian Mountains ; cyclones power dissipation index (PDI) ; monsoon trough ; El Niño southern oscillation (ENSO) ; Indian Ocean dipole (IOD) ; Walker circulation ; predictability ; global ; seasonal precipitation ; ENSO ; MJO ; climate trend ; land use land cover ; Nile River Basin ; water resources ; raindrop spectrum ; radar ; dynamic Z-I ; LSTM neural network ; precipitation estimation ; Loess Plateau ; spring maize ; relative soil moisture ; drought index ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RB Earth sciences::RBP Meteorology & climatology
    Sprache: Englisch
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  • 3
    Publikationsdatum: 2024-04-05
    Beschreibung: After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer. Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action. These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments. Future in vivo work will need to carefully consider the correct choice of chemical modifications to incorporate into the multifunctional nanocarriers to avoid activation off-target, side effects and toxicity. Moreover the majority of studies on nanomaterials do not consider the final application to guide the design of nanomaterial. Instead, the focus is predominantly on engineering materials with specific physical or chemical properties. It is imperative to learn how advances in nanosystem’s capabilities are being used to identify new diagnostic and therapy tools driving the development of personalized medicine in oncology; discover how integrating cancer research and nanotechnology modeling can help patient diagnosis and treatment; recognize how to translate nanotheranostics data into an actionable clinical strategy; discuss with industry leaders how nanotheranostics is evolving and what the impact is on current research efforts; and last but not least, learn what approaches are proving fruitful in turning promising clinical data into treatment realities.
    Schlagwort(e): QD1-999 ; Q1-390 ; Nanoparticles ; Gene Therapy ; Immunotherapy ; bioimaging ; theranostics ; nanomaterials ; Drug delivery ; Nanomedicine ; Cancer ; Phototherapy ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Sprache: Englisch
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-09-11
    Beschreibung: Landscapes and cultural heritage have faced many challenges over time, including modifications and degradation that appear with time, overlaps with other challenges not previously observed, and the influence of cities and management. One of the most visible and globally discussed challenges is climate change. Therefore, there is an urgent need to launch initiatives to tackle climate change and other current challenges from the perspective of landscape and cultural heritage protection. This Special Issue presents selected papers of studies conducted in relation to the 28th Conference on the Series of Garden Art and Historical Dendrology entitled “Climate Change and Current Challenges for Landscapes and Cultural Heritage” that was held on 28 and 29 October 2021. This collection serves as a platform for the exchange of experiences among researchers from different scientific domains.
    Schlagwort(e): nature reserves ; landscape fragmentation ; north–south transitional zone ; spatial differentiation ; Qinling–Daba Mountains ; habitat quality ; water dams ; Krakow fortress ; climate change ; environmental management ; cultural heritage conservation ; urban densification ; prefabricated housing estates ; spatial devastation ; protection of urban layout ; Cracow ; climate change mitigation ; cultural heritage ; urban renewal ; urban parks ; therapeutic landscapes ; climate resilience ; vernacular heritage ; climate narratives ; climate adaptation ; climate stories ; courtyard ; urban green infrastructure ; urban pattern ; supervised classification ; ecosystem services (ES) ; urban cemeteries ; biocultural diversity (BCD) ; urban green infrastructure (UGI) ; questionnaire survey ; Leipzig ; Łódź ; sensory gardens ; urban green spaces ; aromatic herbs ; plant smell memory ; stress ; human wellbeing in urban areas ; restorative environments ; history of gardens ; castle garden ; goosefoot avenue ; star-shaped garden layout ; Austro-Hungarian Empire ; Transylvania as part of Romania ; green infrastructure ; resilience management ; biodiversity ; scenario analysis ; cellular automata model ; historic psychiatric hospitals ; therapeutic landscape ; green therapy ; horticulture therapy ; historical commons ; human cultural heritage ; local development ; landscape values ; rainwater management ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Sprache: Englisch
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  • 5
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    Collège de France
    Publikationsdatum: 2022-02-01
    Beschreibung: La théorie de Darwin aussi bien que sa réception scientifique, littéraire et politique en France continuent d’être matière à débat. Les controverses qu’elle a suscitées à partir de la première traduction française de L’Origine des espèces en 1862 n’ont pas été le seul fait des naturalistes, des géologues ou des paléontologues. De nombreux autres savants se sont préoccupés de l’impact du darwinisme sur leur discipline, notamment en philologie, dans les mathématiques, la linguistique, la psychologie comparée, l’histoire ou la philosophie. Les auteurs des textes réunis dans Darwin au Collège de France montrent que le Collège de France constitue un point de référence idéal pour étudier les idées de Darwin et leur réception ainsi que la manière dont elles ont pu jouer sur la formation des disciplines du milieu du xixe siècle jusqu’à aujourd’hui. Parmi les défenseurs ou les adversaires français du darwinisme, on compte en effet plusieurs de ses professeurs, à commencer par Pierre Flourens, dont l’Examen du livre de M. Darwin (1864) a été l’un des premiers comptes rendus hostiles de L’Origine des espèces. D’autres figurent encore dans la liste : Ernest Renan, Edgar Quinet, Théodule Ribot, Jean-Charles Lévêque, Étienne-Jules Marey, Jean-François Nourrisson, Michel Bréal, Gabriel Tarde, Henri Bergson, Étienne Gilson. À cette liste s’ajoutent les professeurs de biologie, de médecine, de paléontologie, de neurosciences, ou d’économie politique. Le colloque, dont les contributions sur quelques-uns des savants mentionnés ci-dessus sont réunies dans le deuxième volume de la collection « Passage des disciplines », a été organisé par Alain Prochiantz et Antoine Compagnon dans le cadre du projet « Passage des disciplines : Histoire globale du Collège de France, xixe siècle - xxe siècle », qui s’intéresse à l’évolution des matières enseignées aussi bien que celles qui ont n’y ont pas été admises et qui forment un « Collège virtuel », depuis la fin du xviiie siècle jusqu’aux années 1960. Il est dirigé par Antoine Compagnon, avec la collaboration de Céline Surprenant et le soutien financier de PSL (2016-2019), et de la Fondation Hugot.
    Schlagwort(e): P ; D1-2009 ; PN1-6790 ; B1-5802 ; H1-99 ; Q1-390 ; literary criticism ; biology ; psychology ; history of sciences ; social sciences ; literary history ; higher education ; life sciences ; history of ideas ; philosophy ; research
    Sprache: Französisch
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-12-20
    Beschreibung: Anthropogenic greenhouse gas (GHG) emissions are dramatically influencing the environment, and research is strongly committed to proposing alternatives, mainly based on renewable energy sources. Low GHG electricity production from renewables is well established but issues of grid balancing are limiting their application. Energy storage is a key topic for the further deployment of renewable energy production. Besides batteries and other types of electrical storage, electrofuels and bioderived fuels may offer suitable alternatives in some specific scenarios. This Special Issue includes contributions on the energy conversion technologies and use, energy storage, technologies integration, e-fuels, and pilot and large-scale applications.
    Schlagwort(e): Q1-390 ; QC1-999 ; n/a ; PV ; GHG savings ; lithium-ion battery (LIB) ; probability prediction ; decarbonization ; supercapacitor (SC) ; least squares support vector machine ; EV fleet forecasts ; alternative maritime power (AMP) ; Markov chain ; feasibility study ; D funding ; hybrid power system ; numerical analysis ; ship structure ; optimal sizing ; cellulosic ethanol ; electric vehicles EV ; biofuel ; green ship ; R&amp ; bulk carrier ; molten carbonate fuel cell system ; sparse Gaussian process regression ; power-to-gas ; combination method ; charging infrastructure ; jet fuel ; flow characteristics ; hybrid refinery ; LNG-fueled ship ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Englisch
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  • 7
    Publikationsdatum: 2024-04-11
    Beschreibung: It has become more evident that many microalgae respond very differently than land plants to diverse stimuli. Therefore, we cannot reduce microalgae biology to what we have learned from land plants biology. However, we are still at the beginning of a comprehensive understanding of microalgae biology. Microalgae have been posited several times as prime candidates for the development of sustainable energy platforms, making thus the in-depth understanding of their biological features an important objective. Thus, the knowledge related to the basics of microalgae biology must be acquired and shared rapidly, fostering the development of potential applications. Microalgae biology has been studied for more than forty years now and more intensely since the 1970’s, when genetics and molecular biology approaches were integrated into the research programs. Recently, studies on the molecular physiology of microalgae have provided evidences on the particularities of these organisms, mainly in model species, such as Chlamydomonas reinhardtii. Of note, cellular responses in microalgae produce very interesting phenotypes, such as high lipid content in nitrogen deprived cells, increased protein content in cells under high CO2 concentrations, the modification of flagella structure and motility in basal body mutant strains, the different ancient proteins that microalgae uses to dissipate the harmful excess of light energy, the hydrogen production in cells under sulfur deprivation, to mention just a few. Moreover, several research groups are using high-throughput and data-driven technologies, including “omics” approaches to investigate microalgae cellular responses at a system-wide level, revealing new features of microalgae biology, highlighting differences between microalgae and land plants. It has been amazing to observe the efforts towards the development and optimization of new technologies required for the proper study of microalgae, including methods that opened new paths to the investigation of important processes such as regulatory mechanisms, signaling crosstalk, chemotactic mechanisms, light responses, chloroplast controlled mechanisms, among others. This is an exciting moment in microalgae research when novel data are been produced and applied by research groups from different areas, such as bioprocesses and biotechnology. Moreover, there has been an increased amount of research groups focused in the study of microalgae as a sustainable source for bioremediation, synthesis of bioproducts and development of bioenergy. Innovative strategies are combining the knowledge of basic sciences on microalgae into their applied processes, resulting in the progression of many applications that hopefully, will achieve the necessary degree of optimization for economically feasible large-scale applications. Advances on the areas of basic microalgae biology and novelties on the essential cellular processes were revealed. Progress in the applied science showed the use of the basic science knowledge into fostering translational research, proposing novel strategies for a sustainable world scenario. In this present e-book, articles presented by research groups from different scientific areas showed, successfully, the increased development of the microalgae research. Herewith, you will find articles ranging from bioprospecting regional microalgae species, through advances in microalgae molecular physiology to the development of techniques for characterization of biomass and the use of biomass into agriculture and bioenergy production. This e-book is an excellent source of knowledge for those working with microalgae basic and applied sciences, and a great opportunity for researchers from both areas to have an overview of the amazing possibilities we have for building an environmentally sustainable future once the knowledge is translated into novel applications.
    Schlagwort(e): TA1-2040 ; TP248.13-248.65 ; QK1-989 ; Q1-390 ; Biotechnology ; biomass ; Hydrogen ; bioenergy ; Nutrients ; Lipids ; Microalgae ; Biofuels ; sustainability ; Carbon Dioxide ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Sprache: Englisch
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-05-06
    Beschreibung: Wildfire risk can be perceived as the combination of wildfire hazards (often described by likelihood and intensity) with the susceptibility of people, property, or other valued resources to that hazard. Reflecting the seriousness of wildfire risk to communities around the world, substantial resources are devoted to assessing wildfire hazards and risks. Wildfire hazard and risk assessments are conducted at a wide range of scales, from localized to nationwide, and are often intended to communicate and support decision making about risks, including the prioritization of scarce resources. Improvements in the underlying science of wildfire hazard and risk assessment and in the development, communication, and application of these assessments support effective decisions made on all aspects of societal adaptations to wildfire, including decisions about the prevention, mitigation, and suppression of wildfire risks. To support such efforts, this Special Issue of the journal Fire compiles articles on the understanding, modeling, and addressing of wildfire risks to homes, water resources, firefighters, and landscapes.
    Schlagwort(e): wildfire risk ; object-oriented image analysis ; Sentinel-2 ; fire behavior ; flammap ; wildfire management ; water supply ; erosion ; wildfire containment ; Potential fire Operational Delineations ; Monte Carlo simulation ; transmission risk ; WUI ; fire ; defensible space ; prescribed fire ; community vulnerability ; fire suppression costs ; Zillow ; wildfire ; predictive modeling ; fire spread model ; Monte Carlo ; spatial modeling ; area difference index ; statistics ; precision ; recall ; principal components analysis ; risk assessment ; structure loss ; wildland–urban interface ; mitigation ; mapping ; land use ; disaster ; fire spread models ; surrogate modeling ; sensitivity analysis ; global sensitivity analysis ; colour coding ; communication ; forest fire ; ordinal categorization ; palette ; risk ; firefighter safety ; safe separation distance ; safety zones ; LCES ; Google Earth Engine ; lidar ; LANDFIRE ; Landsat ; GEDI ; parcel-level risk ; post-fire analysis ; risk mitigation ; rapid assessment ; natural hazards ; fuels ; fire hazard ; remote sensing ; LiDAR ; Sentinel ; modeling ; simulation ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
    Sprache: Englisch
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-01-05
    Beschreibung: The purpose of this Special Issue was to collect and present research results and experiences on energy supply in the Visegrad Group countries. This research considers both macroeconomic and microeconomic aspects. It was important to determine how the V4 countries deal with energy management, how they have undergone or are undergoing energy transformation and in what direction they are heading. The articles concerned aspects of the energy balance in the V4 countries compared to the EU, including the production of renewable energy, as well as changes in its individual sectors (transport and food production). The energy efficiency of low-emission vehicles in public transport and goods deliveries are also discussed, as well as the energy efficiency of farms and energy storage facilities and the impact of the energy sector on the quality of the environment.
    Schlagwort(e): energy supplies ; energy security ; energy market ; EU countries ; Hellwig’s method ; sustainability strategies ; sustainable development ; Visegrád Group ; sustainable strategic management ; the renewable energy sector ; energy use ; structures ; food production systems ; Visegrad Group ; energy mix ; renewables ; energy in transport ; energetic efficiency ; energy sources ; economic growth ; developing and developed countries ; energy sector ; environmental quality ; renewable energy sources (RES) ; nuclear energy ; southeastern Poland ; sustainability ; renewable energy sources ; European Union ; cluster analysis ; Visegrad Group countries ; fuels ; cointegration ; Granger causality ; electricity prices ; households ; directions of price changes ; biogas energy ; solar energy ; hybrid biogas plant ; renewable energy ; circular economy ; off-grid systems ; energy efficiency ; social and economic aspects of energy ; economic efficiency ; low emissions ; zero emissions ; e-commerce ; last mile ; parcel lockers ; efficiency of logistics processes ; economies of scale ; simulation of logistics processes ; COVID-19 ; BESS management ; price arbitration ; shift load ; microgrid ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Sprache: Englisch
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  • 10
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    SciELO Books - EDUERJ
    Publikationsdatum: 2023-12-20
    Beschreibung: Durante séculos, diversos conhecimentos elaborados e mantidos por grupos sociais considerados à margem da sociedade receberam a classificação de conhecimento popular e conhecimento vulgar, o que demarcou o distanciamento entre esses saberes e o mundo das ciências. Este livro destaca, sob a perspectiva da etnobiologia, o potencial dos saberes tradicionais na construção de ações sustentáveis, refletindo sobre possíveis benefícios para a sociedade. Os autores oferecem análises e informações sobre a contribuição do conhecimento tradicional para a conservação da biodiversidade, para a segurança alimentar e para a saúde, por meio da utilização das plantas medicinais e de outras práticas nativas. O leitor vai perceber que, em muitos momentos, a imposição do mercado ou de pressões políticas não acarretou necessariamente uma melhoria real na alimentação ou na saúde da maior parte da população, como no exemplo dos problemas decorrentes de uma nutrição baseada em alimentos industrializados.
    Schlagwort(e): Q1-390 ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Portugiesisch
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  • 11
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: In the past two decades there have been significant advances made in understanding the cellular and molecular alterations that occur with brain ageing, as well as with our understanding of age-related brain diseases. Ageing is associated with a mid-life decline in many cognitive domains (eg. Attention, working memory, episodic memory) that progresses with advancing age and which may be potentiated by a variety of diseases. However, despite the breadth of attempts to explain it, the underlying basis for age-related memory impairment remains poorly understood. Both normal and “pathological” ageing (as in age-related neurodegenerative disorders such as Alzheimer’s disease) may be associated with overlapping and increased levels of “abnormal” pathology, and this may be a potential mediator of cognitive decline in both populations. An emerging hypothesis in this field is that metal ion dys/homeostasis may represent a primary unifying mechanism to explain age- and disease-associated memory impairment – either indirectly via an effect on disease pathogenesis, or by a direct effect on signaling pathways relevant to learning and memory. There remains a concerted worldwide effort to deliver an effective therapeutic treatment for cognitive decline associated with ageing and/or disease, which is currently an unmet need. There have been numerous clinical trials conducted specifically testing drugs to prevent cognitive decline and progression to dementia, but to date the results have been less than impressive, highlighting the urgent need for a greater understanding of the neurobiological basis of memory impairment in ageing and disease which can then drive the search for effective therapeutics.
    Schlagwort(e): RC321-571 ; Q1-390 ; Down Syndrome ; Amyotrophic Lateral Sclerosis ; Parkinson's disease ; aluminium ; Iron ; TBI ; Cognition ; Copper ; Alzheimer's disease ; Zinc ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-02-20
    Beschreibung: This Special Issue, “Mapping Indigenous Knowledge in the Digital Age”, explores Indigenous engagement with geo-information in contemporary cartography. Indigenous mapping, incorporating performance, process, product, and positionality as well as tangible and intangible heritage, is speedily entering the domain of cartography, and digital technology is facilitating the engagement of communities in mapping their own locational stories, histories, cultural heritage, environmental, and political priorities. In this publication, multimodal and multisensory online maps combine the latest multimedia and telecommunications technology to examine data and support qualitative and quantitative research, as well as to present and store a wide range of temporal/spatial information and archival materials in innovative interactive storytelling formats. It will be of particular interest to researchers engaged in studies of global human and environmental connection in the age of evolving information technology.
    Schlagwort(e): transdisciplinary research ; knowledge dialog ; participatory mapping ; qualitative analysis ; community-based management ; Dawes ; allotment ; GIS ; map ; automation ; PLSS ; geographic information systems ; reservation ; indigenous ; Standing Rock ; community mapping ; learning community ; natural resources management ; Cyberatlas ; Native Americans ; first nations ; historic cartography ; toponymy ; Indigenous maps ; indigital ; undergraduate education ; native science ; Inuinnait ; Inuinnaqtun ; cybercartography ; digital return ; multi-media cartography ; digital heritage ; native guidance system ; Lençóis Maranhenses region ; Maranhão coast ; traditional communities ; Cybercartographic Atlas ; indigenous mappings ; decolonial cartography ; mythical spaces and indigenous orientations ; sky map ; collaborative work ; Pa Ipai ; Baja California ; Mexico ; mapping ; reconciliation ; art ; digital pedagogy ; reflexivity ; Cybercartography ; GIAMedia ; FOSS ; intercultural literacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
    Sprache: Englisch
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  • 13
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Neuromorphic engineering has just reached its 25th year as a discipline. In the first two decades neuromorphic engineers focused on building models of sensors, such as silicon cochleas and retinas, and building blocks such as silicon neurons and synapses. These designs have honed our skills in implementing sensors and neural networks in VLSI using analog and mixed mode circuits. Over the last decade the address event representation has been used to interface devices and computers from different designers and even different groups. This facility has been essential for our ability to combine sensors, neural networks, and actuators into neuromorphic systems. More recently, several big projects have emerged to build very large scale neuromorphic systems. The Telluride Neuromorphic Engineering Workshop (since 1994) and the CapoCaccia Cognitive Neuromorphic Engineering Workshop (since 2009) have been instrumental not only in creating a strongly connected research community, but also in introducing different groups to each other’s hardware. Many neuromorphic systems are first created at one of these workshops. With this special research topic, we showcase the state-of-the-art in neuromorphic systems.
    Schlagwort(e): RC321-571 ; Q1-390 ; neuromorphic engineering ; Learning ; Floating gate ; Neural Network ; spike-based ; event-based ; simulation ; dynamic vision sensor ; network ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 14
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Despite the importance of mathematics in our educational systems little is known about how abstract mathematical thinking emerges. Under the uniting thread of mathematical development, we hope to connect researchers from various backgrounds to provide an integrated view of abstract mathematical cognition. Much progress has been made in the last 20 years on how numeracy is acquired. Experimental psychology has brought to light the fact that numerical cognition stems from spatial cognition. The findings from neuroimaging and single cell recording experiments converge to show that numerical representations take place in the intraparietal sulcus. Further research has demonstrated that supplementary neural networks might be recruited to carry out subtasks; for example, the retrieval of arithmetic facts is done by the angular gyrus. Now that the neural networks in charge of basic mathematical cognition are identified, we can move onto the stage where we seek to understand how these basics skills are used to support the acquisition and use of abstract mathematical concepts.
    Schlagwort(e): RC321-571 ; Q1-390 ; Neuroimaging ; development ; numerosity ; gifted ; Mathematical Cognition ; algebra ; abstract ; Expertise ; Arithmetic ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-06-21
    Beschreibung: The high importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted considerable interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment, suitably designed to be a similar as possible to cellular conditions. This Special Issue provides readers with a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to be used as traces for the discoveries of some relevant biological processes. Several subjects are presented, with five articles and five reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications and bioinspired synthesis, with “free radicals” as the common denominator.
    Schlagwort(e): guanine ; guanyl radical ; tautomerism ; guanine radical cation ; oligonucleotides ; DNA ; G-quadruplex ; time-resolved spectroscopies ; reactive oxygen species (ROS) ; oxidation ; catalase mimics ; peroxide ; diiron-peroxo complexes ; structure/activity ; kinetic studies ; biomimetic chemistry ; cysteine ; ketone reduction ; free radicals ; pulse radiolysis ; kinetics ; DNA oxidation ; DNA hole transfer ; molecular dynamics ; quantum dynamics ; electron transfer ; charge transfer ; quantum coherence ; chemiluminescence ; reaction mechanisms ; singlet oxygen ; reactive oxygen species ; light emission ; crosslink ; dimerization ; protein oxidation ; radicals ; di-tyrosine ; di-tryptophan ; disulfides ; thiols ; aggregation ; proteomics ; mass spectrometry ; collagen ; riboflavin ; hyaluronic acid ; EPR spectroscopy ; keratoconus ; STEM ; DNA biosensor ; chemical nucleases ; DNA-drug interaction ; copper complexes ; metallodrugs ; MEP pathway ; antibiotics ; IspH ; LytB ; [4Fe-4S] cluster ; reductive dehydroxylation ; bioorganometallic intermediate ; inhibitors ; methionine ; neighboring group effect ; hydroxyl radical ; triplet state of carboxybenzophenone ; one-electron oxidants ; laser flash photolysis ; peptides ; proteins ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
    Sprache: Englisch
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  • 16
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-08-08
    Beschreibung: This Special Issue highlights fundamental changes to the questions that we can ask about both the recent past and deep time. Delve into the forefront of paleontological research with this Special Issue reprint. Renowned paleontologists from around the world share groundbreaking insights into ancient life on Earth. Discover the latest advances in fossil discovery, analytical techniques, interdisciplinary collaborations, and technological innovations that are shaping our understanding of evolution and the Earth's history. This collection of cutting-edge research is a must-read for scientists, researchers, and enthusiasts interested in the dynamic field of paleontology in the modern era.
    Schlagwort(e): REE ; Tyrannosaurus rex ; molecular paleontology ; geochemical taphonomy ; diagenesis ; bone ; protein ; collagen ; Hell Creek Formation ; cuticle ; Eocene ; Fur Formation ; insects ; melanin ; mo-clay ; pigment ; Stolleklint Clay ; structural coloration ; Ølst Formation ; fossil ; dinosaur ; paleoproteomics ; porphyrin ; keratin ; feather ; taphonomy ; degradation ; microbes ; CO2 ; apatite ; paleontology ; China ; history ; 20th century ; 21th century ; paleobiology ; history and philosophy of paleontology ; twenty-first-century paleontology ; paleobiological revolution ; technoscience and global issues ; fossil proteins ; rare earth elements ; soft-tissue preservation ; geochemistry ; soft tissues ; molecular preservation ; Hornerstown Formation ; shallow marine ; glauconite ; hybridization ; introgression ; ancient DNA (aDNA) ; hominin paleontology ; paleoanthropology ; Brachylophosaurus ; Judith River Formation ; ELISA ; RIA ; Venta Micena site ; VM-0 ; VM-1960 ; taxonomy ; morphometrics ; phylogeny ; evolution ; morphological clock ; molecular clock ; biodiversity ; palaeobiogeography ; macroevolution ; primates ; Cercopithecidae ; monkeys ; genotype:phenotype mapping ; dentition ; Equidae ; Equinae ; hipparionini ; protohippini ; equini ; paleoecology ; paleoclimatology ; biochronology ; steroids ; diet ; coprolites ; Gryphaea dilatata ; crystallographic texture ; pole figures ; neutron diffraction ; recrystallization ; thick-walled shells ; molecular taphonomy ; fossils ; preservation ; mass spectrometry ; dinosaurs ; Neanderthal ; Combe-Grenal ; juvenile ; mandible ; periodontitis ; tooth ; tartar ; SEM analysis ; n/a ; terrestrialization ; artrhopods ; Cambrian explosion ; molecular clocks ; palaeontology ; phylogenomics ; teeth ; enamel ; microanalysis ; Purussaurus ; Neoepiblema ; miocene ; ICP-MS ; MEV ; microscopy ; magnetic resonance imaging ; micro-computed tomography ; radiocarbon dating ; DNA barcoding ; synchrotron ; bone remodeling ; elemental analysis ; diagenetic alteration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
    Sprache: Englisch
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  • 17
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: In the year 2013, ‘selfie’ was named word of the year by Oxford Dictionaries in recognition of dramatic changes in frequency, prominence, and register of the term. This drastic increase in selfie-taking was spurred by two factors. The first was the advent of smartphones equipped with front cameras and preview screens that made it easy to compose a photographic self-portrait by a process of deliberately exploring one’s image, choosing a pose, and finally taking the picture. The second key change contributing to the rise of the selfie age was the increasing availability of internet connections. It is estimated that about 50% of the world population has access to the internet today (2018; https://www.internetworldstats.com). At the end of the past century, this percentage was a mere 1%. The growth of the internet infrastructure simultaneously spurred the development of social network applications such as Facebook, Twitter, Snapchat, and Instagram, providing accessible media for sharing photographs including photographic self-portraits. However, despite their tremendous reach and popularity, selfies have so far received relatively little attention by the scientific community, especially within psychology. Thus, we proposed a Frontiers in Psychology Research Topic to expand empirical and theoretical work on the massively popular, yet scientifically unexplored, phenomenon of the selfie. The articles published in this eBook offer a multifaceted insight into current scholarly work on this topic.
    Schlagwort(e): BF1-990 ; Q1-390 ; group selfies ; self-esteem ; Human Computer Interaction (HCI) ; self-presentation ; selfie ; viewing perspective ; perception bias ; smartphones ; social media ; internet ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 18
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-06-21
    Beschreibung: This Special Issue introduces recent research results on MEMS packaging and 3D integration whose subjects can be divided as follow; three papers on biocompatible implantable packaging, three papers on interconnect, three papers on bonding technologies, one paper on vacuum packaging, and three papers on modeling and simulation.
    Schlagwort(e): heterogeneous integration ; wafer bonding ; wafer sealing ; room-temperature bonding ; Au-Au bonding ; surface activated bonding ; Au film thickness ; surface roughness ; microelectromechanical systems (MEMS) packaging ; inkjet printing ; redistribution layers ; capacitive micromachined ultrasound transducers (CMUT) ; fan-out wafer-level packaging (FOWLP) ; adhesion ; thin film metal ; parylene ; neural probe ; scotch tape test ; FEM ; MEMS resonator ; temperature coefficient ; thermal stress ; millimeter-wave ; redundant TSV ; equivalent circuit model ; S-parameters extraction ; technology evaluation ; MEMS and IC integration ; MCDM ; fuzzy AHP ; fuzzy VIKOR ; fan-out wafer-level package ; finite element ; glass substrate ; reliability life ; packaging-on-packaging ; thermal sensors ; TMOS sensor ; finite difference time domain ; optical and electromagnetics simulations ; finite element analysis ; ultrasonic bonding ; metal direct bonding ; microsystem integration ; biocompatible packaging ; implantable ; reliability ; Finite element method (FEM) ; simulation ; multilayer reactive bonding ; integrated nanostructure-multilayer reactive system ; spontaneous self-ignition ; self-propagating exothermic reaction ; Pd/Al reactive multilayer system ; Ni/Al reactive multilayer system ; low-temperature MEMS packaging ; crack propagation ; microbump ; deflection angle ; stress intensity factor (SIF) ; polymer packaging ; neural interface ; chronic implantation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
    Sprache: Englisch
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-11-17
    Beschreibung: Symmetry can play an important role in the field of nonlinear systems and especially in the design of nonlinear circuits that produce chaos. Therefore, this Special Issue, titled “Symmetry in Chaotic Systems and Circuits”, presents the latest scientific advances in nonlinear chaotic systems and circuits that introduce various kinds of symmetries. Applications of chaotic systems and circuits with symmetries, or with a deliberate lack of symmetry, are also presented in this Special Issue. The volume contains 14 published papers from authors around the world. This reflects the high impact of this Special Issue.
    Schlagwort(e): chaos ; bifurcation ; closed curve equilibrium ; synchronization ; nonlinear equations ; iterative methods ; rotation–translation formula ; symmetric encryption ; chaotic map ; image encryption ; simultaneous confusion and diffusion ; chaotic oscillator ; lyapunov exponents ; poincare map ; integrated circuit ; fpga ; time-delay ; boolean networks ; hidden attractor ; amplitude control ; offset boosting ; cryptography ; substitution box ; postprocessing ; symmetry ; asymmetry ; chaotic system ; random bit generation ; logistic map ; chaos-based cryptography ; entropy ; prediction ; fractional-order ; glucose-insulin system ; chaotic attractor ; active control ; chaos theory ; electrical circuit analysis ; jerk circuit ; Chua’s diode ; system of differential equations ; quantum mechanics ; molecular quantum transitions ; singularity ; dozy chaos ; dozy-chaos mechanics ; charge transfer ; condensed matter ; direct and reverse processes ; optical band shapes ; Egorov resonance ; hyperchaotic behavior ; arduino microcontrollers ; optical channel ; chaotic flow ; hyperbolic sinusoidal function ; voice encryption ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Sprache: Englisch
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  • 20
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-08-08
    Beschreibung: The World Health Organization recommends the consumption of plant foods instead of animal-origin foods due to their high levels of saturated fat and cholesterol. Consumption of plant products has led to research on the beneficial properties of their components beyond basic nutrients. Vegetable-derived peptides have shown multifunctional effects related to chronic diseases, attracting interest from the food, nutraceutical, and pharmaceutical industries. This reprint highlights studies on various vegetable extracts, such as chestnut, quinoa, amaranth, buckwheat, and Protium heptaphyllum gum resin, which have demonstrated antimicrobial, anti-inflammatory, and cholesterol-regulating properties. Specific compounds derived from plants, such as methyl p-coumarate and lupin protein hydrolysate, have shown effectiveness in reducing inflammation and anxiety, respectively. A vegetable extract of rosemary has been studied for its potential to treat osteogenesis imperfecta. Moreover, this repprint reviews Lycium barbarum berries, essential oils from Annonaceae species, antioxidant compounds, phytosterols, and natural compounds for the prevention and treatment of oral mucositis was discussed. Overall, these studies suggest that vegetable-derived bioactive compounds could serve as new nutraceuticals to prevent and treat a wide range of chronic diseases.
    Schlagwort(e): hypercholesterolemia ; gene expression ; HMGCR ; PCSK9 ; PPARα ; enzymatic activity ; molecular docking ; statin ; monacolin ; breu branco ; seed storage proteins ; peptides ; anti-inflammatory ; antioxidant ; trypsin inhibitors ; quinoa ; amaranth ; buckwheat ; in vitro gastro-intestinal digestion ; natural products ; Brazilian species ; essential oil ; applications ; phytosterols ; neurodegeneration ; Alzheimer’s disease ; blood brain barrier ; obesity ; oxidative stress ; dyslipidemia ; diabetes ; enzyme-assisted extraction ; plant material ; phenolic compounds ; oligosaccharides ; prebiotic ; nanocellulose ; nanofibers ; fermentation ; sustainability ; cancer ; drug delivery ; oral mucositis ; treatment ; lupin ; protein hydrolysates ; anxiety ; ApoE−/− ; functional foods ; peptidomics ; rosemary extract ; collagen type I ; unfolded protein response ; autophagy ; proteasome ; skin fibroblasts ; apoptosis ; osteogenesis imperfecta ; asthma ; methyl p-coumarate ; Th2 cytokines ; eosinophil ; NF-κB ; Castanea sativa shells ; Subcritical Water Extraction (SWE) ; antimicrobial activity ; goji berries ; pro-healthy effects ; phenolics ; biological properties ; functional ingredients ; in vitro cultures ; Ruta montana ; coumarins ; alkaloids ; antibiofilm formation ; antibacterial activity ; antioxidant activity ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
    Sprache: Englisch
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  • 21
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Schlagwort(e): QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 22
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    Frontiers Media SA
    Publikationsdatum: 2024-03-31
    Beschreibung: The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydroxyvitamin D3(1a,25(OH)2D3), are calcium and phosphorus uptake and transport and thereby controlling bone formation. Other emergent areas of 1a,25(OH)2D3 action are in the control of immune functions, cellular growth and differentiation. This fits both with the widespread expression of the VDR and the above described consequences of vitamin D deficiency. Transcriptome-wide analysis indicated that per cell type between 200 and 600 genes are primary targets of vitamin D. Since most of these genes respond to vitamin D in a cell-specific fashion, the total number of vitamin D targets in the human genome is far higher than 1,000. This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980’s. Thus, vitamin D signaling primarily implies the molecular actions of the VDR. In this research topic, we present in 15 chapters different perspectives on the action of vitamin D and its receptor, such as the impact of the genomewide distribution of VDR binding loci, ii) the transcriptome- and proteome-wide effects of vitamin D, iii) the role of vitamin D in health, iv) tissue-specific functions of vitamin D and v) the involvement of vitamin D in different diseases, such as infections, autoimmune diseases, diabetes and different types of cancer.
    Schlagwort(e): QP1-981 ; Q1-390 ; Vitamin D ; Immune System ; Genomics ; vitamin D receptor ; Physiology ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Sprache: Englisch
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  • 23
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-04-05
    Beschreibung: Considering the worldwide problem of aquatic pollution, we proposed this reprint, which presents a collection of articles on different aspects of environmental pollution, from monitoring to the evaluation of toxicity. In particular, the volume concerns the issues specifically related to emerging contaminants in aquatic environments, such as plastics and pharmaceuticals. However, to confer to this volume a more holistic view, some articles on priority pollutants, such as heavy metals and pesticides, are also reported.
    Schlagwort(e): aquatic ecosystems ; pollution ; monitoring ; toxic effects ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
    Sprache: Englisch
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  • 24
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-04-05
    Beschreibung: This Special Issue of the journal Axioms collects submissions in which the authors report their perceptions and results in the field of mathematical physics and/or physical mathematics without any preconditions of the specific research topic. The papers are intended to provide the reader with a broad window into the status of the research field showing our understanding of how a known concept changes our thinking in that area of science. The papers in the Special Issue highlight the current two issues in physics and mathematics under hot debate: fractional calculus and entropy.
    Schlagwort(e): weak detonation ; high activation regime ; nonlinear PDEs ; Fuchsian reduction analysis ; Lorentz transformation ; blow-up ; hot spot ; chemically reactive flows ; nonlinear equations in partial derivatives ; hyperbolic equations ; Bäcklund transformations ; Clairin’s method ; differential relationships ; the Liouville equation ; symbolic calculus ; canonical system of q-difference equations ; q-Euler integral ; multi-term fractional differential equation ; quasilinear equation ; Riemann–Liouville fractional derivative ; defect of Cauchy type problem ; fixed point theorem ; initial-boundary value problem ; deformed numbers ; deformed algebras ; deformed calculus ; nonadditive entropy ; vibration control ; boundary control ; intermediate state control ; separation of variables ; Riemann–Liouville fractional differential equations ; nonlocal boundary conditions ; positive parameters ; positive solutions ; existence ; nonexistence ; Patlak–Keller–Segel systems ; the Cattaneo model of chemosensitive movement ; hyperbolic models ; shock waves ; conservation laws ; constrained Hamiltonian system ; canonicalization ; symplectic method ; numerical simulation ; extended Chebyshev functional ; generalized proportional Hadamard fractional integral operator ; manipulation system ; geometric approach ; noninteraction ; two-phase flow ; Sobolev spaces ; analytic semigroups ; fractional interpolation ; local and global solutions ; seismic tensorial force ; far-field seismic waves ; near-field seismic waves ; seismic mainshock ; quasi-static deformations ; mathematical physics ; Elliott Lieb ; the International Association of Mathematical Physics (IAMP, history and development) ; Letters in Mathematical Physics (LMP) ; history ; God as an (optional) axiom ; metamathematics ; symmetries ; particle physics ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science ; bic Book Industry Communication::P Mathematics & science::PB Mathematics::PBT Probability & statistics
    Sprache: Englisch
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  • 25
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    SciELO Books - Editora UEPG
    Publikationsdatum: 2023-12-20
    Beschreibung: Dividido em três partes, este livro enfoca o turismo em áreas naurais, destacando o geoturismo, abrange aspectos ligados à geoconservação em áreas protegidas e os Geoparques e por fim aborda a educação e interpretação ambiental, incluindo diversos exemplos de atividades geoeducativas, interpretativas e turísticas.
    Schlagwort(e): Q1-390 ; SCIENCE ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Portugiesisch
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  • 26
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-07-06
    Beschreibung: The first experiments on electron scattering were completed before the “official” discovery of this particle by J. J. Thomson. In spite of this, our knowledge of cross sections is still far from complete.More recent experiments had some unexpected results, like selective fragmentation of DNA constituents by low-energy electrons, or “reverse” phenomena, i.e., synthesis of simple amino acids from inorganic precursors, triggered by slow electrons. The most recent need for cross sections comes from modeling plasmas for industrial and thermonuclear applications, and atmospheres of solar and extra-solar planets.Both fundamental research (experiments, theory, reviews) and applications of electron-scattering cross sections in various processes are welcome.
    Schlagwort(e): ionization ; electron ; positron ; few body ; electron scattering ; integral cross sections ; alcohols ; isomeric effect ; butanol ; pentanol ; electron mobility ; multiple-scattering effects ; disordered systems ; weak localization ; electron and positron scattering ; spin asymmetry ; critical minima ; total polarization ; coulomb glory ; water ; vibrational excitation ; R-matrix ; electron-molecule collisions ; interstellar medium ; model potential ; wave-packet propagation ; vibrational cross-section ; backscattering ; electron optics ; inelastic collisions ; numerical simulations ; electron ionization ; electron capture ; helium droplets ; cross section ; MCDF wavefunctions ; wavelengths ; transition rates ; relativistic distorted wave method ; cross sections ; rate coefficients ; ionizing radiation ; dissociative electron attachment ; mass spectrometry ; DNA damage ; cross-section calculations ; plasma simulation ; electron atomic collisions ; ionization cross section ; approximation of cross sections ; alkali metals ; noble gases ; electron elastic scattering ; scattering cross-sections ; positron scattering ; total cross-sections ; dispersion relation ; electron scattering cross sections ; electron transport in gases ; electron track simulation ; positron impact ionization ; positron-molecule scattering ; binary-encounter-Bethe ; argon optical emission spectroscopy ; plasma processing ; coronal models ; collisional-radiative model ; nonlocal thermodynamic equilibrium plasmas ; population kinetics ; radiation transport ; opacity effects ; Non-Maxwellian plasmas ; metastable states ; electron-impact ionization ; BEB approach ; elementary processes in plasmas ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Sprache: Englisch
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  • 27
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Glial cells are no longer considered passive bystanders in neuronal brain circuits. Not only are they required for housekeeping and brain metabolism, they are active participants in regulating the physiological function and plasticity of brain circuits and the online control of behavior both in invertebrate and vertebrate model systems. In invertebrates, glial cells are essential for normal function of sensory organs (C. elegans) and necessary for the circadian regulation of locomotor activity (D. melanogaster). In the mamallian brain, astrocytes are implicated in the regulation of cortical brain rhythms and sleep homeostasis. Disruption of AMPA receptor function in a subset of glial cell types in mice shows behavioral deficits. Furthermore, genetic disruption of glial cell function can directly control behavioral output. Regulation of ionic gradients by glia can underlie bistability of neurons and can modulate the fidelity of synaptic transmission. Grafting of human glial progenitor cells in mouse forebrain results in human glial chimeric mice with enhanced plasticity and improved behavioral performance, suggesting that astrocytes have evolved to cope with information processing in more complex brains. Taken together, current evidence is strongly suggestive that glial cells are essential contributors to information processing in the brain. This Research Topic compiles recent research that shows how the molecular mechanisms underlying glial cell function can be dissected, reviews their impact on plasticity and behavior across species and presents novel approaches to further probe their function.
    Schlagwort(e): RC321-571 ; Q1-390 ; Cerebellum ; C. elegans ; Astrocytes ; DREADD ; Cortex ; plasticity ; Gq ; Behavior ; glia ; Hippocampus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 28
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    IRD Éditions
    Publikationsdatum: 2023-12-20
    Beschreibung: Le fleuve Niger constitue un véritable poumon humide pour l’Afrique de l’Ouest et plus spécialement pour la république du Mali. Dans ce pays, la gestion du fleuve constitue un enjeu majeur car on y trouve à la fois de remarquables systèmes de production traditionnels associés au phénomène naturel de crue – sources de moyens d’existence pour des centaines de milliers de personnes – mais aussi de grandes réalisations et promesses en matière d’aménagements modernes, hydroélectriques et hydroagricoles. À l’heure où de nouveaux projets d’équipement arrivent à concrétisation et où d’autres sont annoncés, il est important de faire le point sur l’état de santé de ce fleuve et de peser ce qu’il représente pour ses multiples usagers. Cette expertise collégiale, conduite par l’IRD et l’IER et réalisée avec le soutien de plusieurs institutions d’aide au développement et de défense de l’environnement, traite de ces différents aspects avec pour objectif, d’une part, la clarification des cadres institutionnels et des options de politiques publiques et, d’autre part, le renforcement des outils de suivi et d’aide à la décision.
    Schlagwort(e): Q1-390 ; aménagement hydroélectrique ; écosystème ; irrigation ; Niger cours d’eau ; aménagement hydroagricole ; Mali ; exploitation des ressources naturelles ; eau ; bassin versant ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Französisch
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  • 29
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-07-06
    Beschreibung: It is our pleasure to present this Special Issue of Molecules entitled “Food Processing and Its Impact on Phenolic and other Bioactive Constituents in Food”. Bioactive compounds including phenolic ingredients have long been used as important constituents of a healthy diet. As a result, consumer awareness about the important role of high-quality products rich in bioactive compounds—especially phenolic compounds—in human nutrition, health, and prevention against diseases has increased. Additionally, methods for food processing, regardless of the technology used, have a huge impact on the quality of the final products. Therefore, the big challenges for scientists lie in the monitoring of changes during food processing and the optimization of technology to achieve the minimal degradation of nutrients (including phenolic compounds). Thus, for this Special Issue, I encourage you to read some interesting papers aimed at bringing the latest scientific news, insights, and advances in the field of food processing and its impact on bioactive constituents in food, especially phenolic compounds. The information presented will certainly arouse considerable interest among a large group of our readers from different disciplines and research fields.
    Schlagwort(e): apple ; phenolic compounds ; genetic resources ; HPLC-DAD ; thyme ; oregano ; dry herbs ; polyphenols ; chlorophyll ; carotenoids ; microbial ; cytotoxicity ; dissolution test ; functional food ; innovative food ; drying ; natural food ; Helianthus tuberosus ; pro-healthy properties ; plant polyphenols ; food processing ; phenolic content ; bioavailability ; bioaccessibility ; coffee Arabica ; roasting process ; brewing methods ; antioxidant activity ; flavonoids ; caffeine ; pH of infusions ; tannins ; snack ; baking ; carotenoids content ; chlorophyll content ; total polyphenols content ; calorific value ; sensory properties ; sourdough fermentation ; inoculation ; lactic acid bacteria ; FODMAP ; fructans ; antioxidants ; chocolate ; free radical scavenging activity ; reducing power ; functionalization of food ; electronic nose analysis ; isoflavone conversion ; thermal process ; immature seeds ; mature seeds ; internal water content ; konjac ; linseed flour ; fat substitute ; volatile compounds ; lipid oxidation ; encapsulation ; Mauritia flexuosa (aguaje) ; controlled dehydration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
    Sprache: Englisch
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  • 30
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-04-05
    Beschreibung: The eradication of vector-borne diseases is threatened by the limited range of available insecticides, leading, inevitably, to the development of resistance. This is particularly concerning for malaria control, which relies heavily on insecticide-treated nets (ITNs) and indoor residual sprays (IRS). New chemistries are being developed, and innovative deployment of insecticides may play a role in overcoming resistance, either through new types of tools or new means of distribution. A variety of novel product types and vector control strategies are under development and evaluation, which is to be celebrated, but a strong evidence base is needed to guide effective operational deployment decisions. Novel approaches should be supported by robust data collected using appropriate and validated methods to monitor efficacy, durability, and any emerging resistance. This reprint presents original research into developing and characterizing new vector control products, as well as understanding and monitoring insecticide resistance. Review articles explore the impact of insecticide resistance and offer guidance on insecticide choice in the face of pyrethroid resistance. Consensus methodologies are presented, in the form of standard operating procedures (SOPs) designed to be adopted and used to generate reproducible data that can be compared and interpreted across and between studies. It is hoped that this collection of articles offers inspiration and guidance on how consistent data can be generated to inform more effective development, evaluation, and use of new and existing vector control tools.
    Schlagwort(e): prallethrin ; insecticide ; spatial treatment ; mosquito fitness ; protection ; pyrethroids ; Aedes albopictus ; Culex pipiens ; life tables ; mosquito ; bite-proof garment ; model ; textile ; non-insecticidal ; physical barrier ; insecticide selection ; out-crossing ; strain authentication ; laboratory screening ; pyrethroid ; pyrethroid resistance ; insecticide resistance ; insecticide resistance management ; vector control ; malaria ; malaria control ; Anopheles ; host-seeking behavior ; insecticide exposure ; pathogen transmission ; Aedes aegypti ; Anopheles gambiae ; ATSB ; Culex quinquefasciatus ; Iroquois ; RNAi ; Saccharomyces cerevisiae ; yeast ; Anopheles mosquito ; fertility ; ovary development ; pyriproxyfen (PPF) ; side-effects ; machine learning ; image classification ; automated identification ; convolutional neural network ; insecticide-treated net (ITN) ; PBO ITN ; synergist ITN ; dual-AI ITN ; insecticide resistance management (IRM) ; method validation ; durability monitoring ; bioinsecticide ; disease transmission ; insecticide-resistance ; mosquito-borne disease ; mosquito control ; natural compounds ; phytochemical ; malaria vector ; insecticide treated nets ; cytochrome P450s ; kdr ; cuticular resistance ; deltamethrin ; imidacloprid ; bifenthrin ; β-cyfluthrin ; etofenprox ; α-cypermethrin ; λ-cyhalothrin ; thiacloprid ; mosquitoes ; Attractive Toxic Sugar Bait (ATSB) ; Attractive Targeted Sugar Bait (ATSB) ; diagnostic bioassay ; resistance monitoring ; insecticide-treated nets (ITN) ; strain characterisation ; method development ; product evaluation ; quality control (QC) ; dual active ingredients (dual-AI) ; bioefficacy ; IRS ; application technology ; broflanilide ; clothianidin ; pirimiphos-methyl ; WHO tube ; WHO tunnel test ; ITNs ; interceptor ; interceptor G2 ; membrane ; human arm ; rabbit ; bioassay ; bio-efficacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
    Sprache: Englisch
    Format: application/octet-stream
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  • 31
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies is a Special Issue of the International Journal of Neonatal Screening. Sickle cell disease is one of the most common inherited blood disorders, with a huge impact on health care systems due to high morbidity and high mortality associated with the undiagnosed disease. Newborn screening helps to make the diagnosis early and to prevent fatal complications and diagnostic odysseys. This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.
    Schlagwort(e): QD1-999 ; Q1-390 ; glucose-6-phosphate dehydrogenase ; hydroxyurea/hydroxycarbamide ; n/a ; cord blood ; screening ; hemoglobin pattern ; capillary electrophoresis ; sickle cell disease ; (recommended) screening panel ; vaso-occlusive crisis ; Guthrie spots ; newborn screening) ; foetal haemoglobin ; harmonisation ; review ; birth prevalence ; G6PD deficiency ; prevention ; end-organ damage ; thalassemia ; MALDI-TOF ; IEF ; acute chest syndrome ; India ; sickle cell and thalassaemia screening programme ; ‘Getting to Outcomes’ ; newborn screening ; hemoglobinopathy ; service users ; public health engagement ; automated HPLC ; Kaduna State ; gene therapy for haemoglobinopathies ; ?-globin gene ; methods ; neonatal screening program ; malaria ; Plasmodium vivax ; sub-Saharan Africa ; patient organisations ; health policy ; pathophysiology ; Sickle Cell Disease ; mass spectrometry ; sickle cell disorder ; neonatal screening ; non-tribal ; Nigeria ; point-of-care ; HPLC ; laboratory methods ; registry ; patient advocacy ; bone marrow transplant ; anaemia ; hemoglobinopathies ; tribal ; newborn ; burden of disease ; patient representatives ; diagnostics ; policy making ; haemolysis ; Caribbean ; high performance liquid chromatography (HPLC) ; sickle cell disease (SCD) ; implementation science ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 32
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-01-05
    Beschreibung: Phenolic compounds in food such as fruits, vegetables, wine, spices, and oils have been characterized and their possible effects on human health has been studied in depth. Several technological aspects have also been considered concerning the sustainable extraction of phenolic compounds, the long-term storage effects, and the influence of fermentation and boiling techniques on their properties.
    Schlagwort(e): chestnut ; water curing ; non-targeted MS analysis ; antioxidants ; Arecaceae ; polyphenols ; volatile content ; antioxidant activity ; liquid chromatography ; inflammation ; lung ; oxidative damage ; antiviral ; polyphenol ; phenolic acids ; flavonoids ; Vicia faba ; functional food ; green solvents ; biologically active compounds ; selective separation ; medicinal plants ; ultrasonic-assisted extraction ; microwave-assisted extraction ; kombucha ; black tea ; long-term storage ; antioxidant scavenging activity ; total phenolic content ; meat quality ; antimicrobial activity ; C. scolymus ; food quality ; beverages ; health properties ; antioxidant activities ; fibrinogen ; albumin ; rutin ; tannic acid ; resveratrol ; binding properties ; first order ; kinetic modelling ; zero order ; food processing ; herbal tea ; boiling ; EVOO ; vegetables ; phenolic compounds ; thermal treatment ; processing techniques ; bioaccessibility ; bioavailability ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
    Sprache: Englisch
    Format: image/jpeg
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  • 33
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-07-06
    Beschreibung: The articles in this Special Issue cover a very wide range of topics related to the cultivation, management and use of fast-growing tree species. In addition to research on breeding and on the influence of pruning practices on the height growth of paulownia, three articles deal with the influence of site characteristics and nutrient availability on the physiology and yield security of fast-growing tree species. Another article focuses on the modeling of soil carbon in Salix plantations, while the article by Boruszewski et al. reports on potentially suitable areas for the planting of fast-growing tree species in Poland. Zitzmann and Rode examine the impact of short-rotation plantation management on phytodiversity, while Helbig et al. deal with the influence of leaf feeding on the growth of poplars and willows. Finally, Hernandez-Estrada et al. describe the dry matter loss of poplar wood chips during storage.
    Schlagwort(e): woody biomass crops ; bioenergy ; biodiversity ; species richness ; flora ; vascular plants ; short rotation coppices ; poplars ; willows ; feeding simulation ; defoliation ; herbivory ; short rotation coppice ; phosphatase activity ; nutrient content ; growth stages ; biomass ; willow ; Salix ; capacity ; European larch ; fast-growing trees ; plantations ; plantation area ; poplar cultivar “Hybrid 275” ; sown area ; biomass production ; life cycle assessment ; climate impact ; soil organic carbon ; genotypic difference ; CRISPR/Cas9 ; genome editing ; Populus ; INRA 717-1B4 ; pyramidal plant habitus ; leaf petiole angle ; branch angle ; nitrogen ; phosphorus ; carbon ; physiology ; F. mandshurica ; Robinia pseudoacacia L. ; photosynthetic vitality ; chlorophyll and phenol content ; nutrition supply ; dry matter yield ; land reclamation ; spring pruning ; year-long pruning ; branching ; angle diversion of sprout ; dry matter losses ; poplar wood chips ; laboratory scale ; cultivable saproxylic microbiota ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 34
    Publikationsdatum: 2024-04-05
    Beschreibung: In this EBook, we highlight how newly emerging techniques for non-invasive manipulation of the human brain, combined with simultaneous recordings of neural activity, contribute to the understanding of brain functions and neural dynamics in humans. A growing body of evidence indicates that the neural dynamics (e.g., oscillations, synchrony) are important in mediating information processing and networking for various functions in the human brain. Most of previous studies on human brain dynamics, however, show correlative relationships between brain functions and patterns of neural dynamics measured by imaging methods such as electroencephalography (EEG), magnetoencephalography (MEG), near-infrared spectroscopy (NIRS), positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). In contrast, manipulative approaches by non-invasive brain stimulation (NIBS) have been developed and extensively used. These approaches include transcranial magnetic stimulation (TMS) and transcranial electric stimulation (tES) such as transcranial direct current stimulation (tDCS), alternating current stimulation (tACS), and random noise stimulation (tRNS), which can directly manipulate neural dynamics in the intact human brain. Although the neural-correlate approach is a strong tool, we think that manipulative approaches have far greater potential to show causal roles of neural dynamics in human brain functions. There have been technical challenges with using manipulative methods together with imaging methods. However, thanks to recent technical developments, it has become possible to use combined methods such as TMS–EEG coregistration. We can now directly measure and manipulate neural dynamics and analyze functional consequences to show causal roles of neural dynamics in various brain functions. Moreover, these combined methods can probe brain excitability, plasticity and cortical networking associated with information processing in the intact human brain. The contributors to this EBook have succeeded in showcasing cutting-edge studies and demonstrate the huge impact of their approaches on many areas in human neuroscience and clinical applications.
    Schlagwort(e): RC321-571 ; Q1-390 ; non-invasive brain stimulation NIBS ; TMS-EEG ; Transcranial magnetic stimulation TMS ; transcranial electric stimulation tES ; Coregistration ; Near-infrared spectroscopy NIRS ; Functional magnetic resonance imaging fMRI ; transcranial direct current stimulation tDCS ; transcranial alternating current stimulation tACS ; transcranial random noise stimulation tRNS ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 35
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-02-01
    Beschreibung: This book presents the advances in plant salinity stress and tolerance, including mechanistic insights revealed using powerful molecular tools and multi-omics and gene functions studied by genetic engineering and advanced biotechnological methods. Additionally, the use of plant growth-promoting rhizobacteria in the improvement of plant salinity tolerance and the underlying mechanisms and progress in breeding for salinity-tolerant rice are comprehensively discussed. Clearly, the published data have contributed to the significant progress in expanding our knowledge in the field of plant salinity stress and the results are valuable in developing salinity-stress-tolerant crops; in benefiting their quality and productivity; and eventually, in supporting the sustainability of the world food supply.
    Schlagwort(e): watermelon ; salt stress ; RNA-seq ; amino acids ; endocytosis ; Arabidopsis thaliana ; halophyte ; high-affinity potassium transporter (HKT) ; Na+ transporter ; salt tolerance ; Sporobolus virginicus ; aquaporins ; barley ; ion transport ; oocytes ; plasma membrane intrinsic proteins (PIPs) ; GmbZIP15 ; transcription factor ; drought stress ; soybean ; biotechnology breeding ; high-throughput sequencing ; QTLs ; rice ; halophytic wild barley ; salinity ; osmotic stress ; metabolome ; transcriptome ; ionome ; stress adaptation ; Hordeum marinum ; aquaporin ; Zygophyllum xanthoxylum ; plant growth ; abiotic stress ; sensing ; signaling ; transcription factors ; osmoregulation ; antioxidation ; ion homeostasis ; jasmonates ; jasmonate signaling pathway ; crosstalk ; exogenous jasmonate applications ; GWAS ; PGPR ; ACC deaminase ; seed priming ; IAA ; cell wall integrity ; cell wall sensor ; LRXs ; CrRLK1Ls ; Millettia pinnata ; calmodulin-like ; heterologous expression ; halophiles ; plant growth-promoting rhizobacteria (PGPR) ; RNA sequence analysis (RNA-seq) ; quantitative reverse transcriptase PCR (qRT-PCR) ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
    Sprache: Englisch
    Format: image/jpeg
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  • 36
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-05-06
    Beschreibung: In recent years, new and emerging digital technologies applied to food science have been gaining attention and increased interest from researchers and the food/beverage industries. In particular, those digital technologies that can be used throughout the food value chain are accurate, easy to implement, affordable, and user-friendly. Hence, this Special Issue (SI) is dedicated to novel technology based on sensor technology and machine/deep learning modeling strategies to implement artificial intelligence (AI) into food and beverage production and for consumer assessment. This SI published quality papers from researchers in Australia, New Zealand, the United States, Spain, and Mexico, including food and beverage products, such as grapes and wine, chocolate, honey, whiskey, avocado pulp, and a variety of other food products.
    Schlagwort(e): sensory ; physicochemical measurements ; artificial neural networks ; near infra-red spectroscopy ; wine quality ; machine learning modeling ; weather ; consumer acceptance prediction ; data fusion ; emotion recognition ; facial expression recognition ; galvanic skin response ; machine learning ; neural networks ; sensory analysis ; avocado ; cultivars ; preference mapping ; sensory evaluation ; sensory descriptive analysis ; consumer science ; unifloral honeys ; botanical origin ; physicochemical parameters ; classification ; natural language processing ; deep learning ; sensory science ; flavor lexicon ; long short-term memory ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
    Sprache: Englisch
    Format: image/jpeg
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  • 37
    Publikationsdatum: 2024-04-05
    Beschreibung: Bálint’s syndrome is named after the Hungarian physician who first reported a remarkable case of a man with complex visuospatial deficits following bilateral lesions within parietal and occipital cortex (Bálint, 1909). The syndrome has three primary symptoms: simultanagnosia (impaired spatial awareness of more than one object at time), optic ataxia (misreaching to visual targets) and ocular apraxia (described by Bálint as “psychic paralysis of gaze”). Balint’s patients not only cannot perceive more than one object at time and therefore show poor comprehension of multi-object visual scenes i.e. poor detection of all the objects present and difficulty in grasping the relationship between them; in addition they typically fail to reach towards location of the single object, which they can perceive. The deficit of the allocation of spatial attention in Balint’s syndrome has been linked to a problem in feature binding which results in illusory conjunctions. Patients with Balint’s syndrome also show deficits in global processing i.e. when integration of multiple local elements into global compound shapes is required. Consequently, Balint’s syndrome provides a unique opportunity to study the nature and neuroanatomy of human visuospatial processing, in particular multi-level object representation, spatial awareness and the distribution of visual attention. The studies collected here cover both the anatomical and the cognitive mechanisms of the different symptoms associated with the syndrome. Furthermore, the dissociations between the components of Bálints’ syndrome, in particular simultanagnosia and optic ataxia, can also co-occur with visual neglect and extinction and the different combinations of reported lesions raises a question about the status of the syndrome and whether it should be merely treated as a historical compilation of symptoms which may or may not coexist cohesively. This interesting argument is raised here.
    Schlagwort(e): RC321-571 ; Q1-390 ; posterior cortical atrophy ; Balints syndrome ; optic ataxia ; Posterior parietal cortex ; simultanagnosia ; ocular apraxia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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    Standort Signatur Erwartet Verfügbarkeit
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  • 38
    Publikationsdatum: 2024-04-05
    Beschreibung: The tale of cyclic GMP has been astonishing. Having overcome an initial disbelief, cyclic GMP has risen to its present eminence as a premium cellular signal transduction messenger of not only hormonal extracellular but also of the intracellular signals. This research topic focuses on the pathways and functions of membrane guanylate cyclases in different tissues of the body and their interplay with intracellular sensory signals where in many cases, cyclic GMP along with Ca2+ have taken on roles as synarchic co-messengers.
    Schlagwort(e): RC321-571 ; Q1-390 ; Glaucoma ; Visceral Pain ; Calcium ; membrane guanylate cyclase ; ANF-RGC ; Gene Therapy ; Cyclic GMP ; synaptic plasticity ; trafficking ; ROS-GC ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 39
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-02-02
    Beschreibung: This reprint reviews a crop pest management use for several essential oils and the properties of an excellent lemon (citral) source. Research is reported on the biological properties of enhanced lemon oil along with the human intake of citrus beverages and the less common medicinal mastiha oil. Oils and hydrolates of rosemary and lavender were analyzed by headspace/GC-MS to better define their antibacterial, antioxidant and cytotoxic activities, and yeast particle encapsulation was investigated for the controlled release of bioactive terpenes.
    Schlagwort(e): monoterpenes ; mastiha oil ; absorption ; Citrus limon (L.) Osbeck ; essential oil ; citral ; nutraceuticals ; inflammation ; oxidative stress ; terpenes ; yeast particles ; antimicrobial ; anthelmintic ; prodrug ; beverages ; Citrus ; coumarins ; furocoumarins ; polymethoxyflavones ; linear retention indices ; liquid chromatography ; tandem mass spectrometry ; multiple reaction monitoring ; quality control ; Backhousia citriodora ; lemon myrtle ; lemon oils ; geranial ; neral ; iso-citrals ; citronellal ; flavor ; fragrance ; biological activity ; Lavandula angustifolia ; Rosmarinus officinalis ; essential oils ; hydrolates ; chemical analysis ; volatile compounds ; phytochemicals ; synergism ; fractional inhibitory concentration ; insect mortality rate ; phytopathogenic fungi ; insect pests ; pesticide resistance ; fungicide resistance ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 40
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-02-01
    Beschreibung: This book is relevant to architects, urban designers, planners, and policy makers concerned with enhancing climate-sensitive urban form and planning. It discusses building and neighborhood design: layout and design features that maximize energy efficiency and thermal comfort without compromising the ability of other buildings to enjoy similar benefits; the use of interstitial spaces (piazzas, streets, and parks) to improve the microclimate at the neighbourhood-level; design intervention case studies; innovative uses of interstitial spaces to improve the local climate at the neighborhood level; and urban radiative cooling solutions to mitigate the unintended climate consequences of urban growth and suggestions for ways forward.
    Schlagwort(e): cooling effect ; urban park ; thermal comfort ; physiological equivalent temperature ; perceived thermal comfort ; urban heat island ; air temperature ; sustainable cities ; smart cities ; urban health ; global warming ; urban green spaces ; sustainable urban development ; climate change mitigation and adaptation ; urban resilience  ; heatwaves ; urban overheating ; urban heat island intensity ; energy budget equation ; sensible heat flux ; latent heat flux ; advective heat flux ; Australian climatic conditions ; coastal cities ; desert climate ; surface urban heat island effect ; land use/land cover ; partial least square regression ; nonlinear programming ; Shanghai ; China ; urban form ; urban microclimate design ; city ; sustainability ; sustainable development ; cool roof ; passive radiative cooling ; metamaterials ; prototype ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::P Mathematics & science::PH Physics::PHH Thermodynamics & heat
    Sprache: Englisch
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  • 41
    Publikationsdatum: 2024-04-05
    Beschreibung: In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervous system. Ion channels are the large proteins that form regulated pores in the membranes of cells and, in the brain, are essential for the transfer, processing and storage of information. These pores full of twists and turns themselves are not just barren bridges into cells. More and more we are beginning to understand that ion channels are like bustling medieval bridges (packed with apartments and shops) rather than the more sleek modern variety – they are dynamic hubs connected with many structures facilitating associated activities. Our understanding of these networks continues to expand as our investigative tools advance. Together these articles highlight how the complexity of ion channel signaling nexuses is critical to the proper functioning of the nervous system.
    Schlagwort(e): RC321-571 ; Q1-390 ; Nervous System ; Ion Channels ; Interactome ; cellular signaling ; Protein complexes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 42
    Publikationsdatum: 2024-04-05
    Beschreibung: Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer.
    Schlagwort(e): QH426-470 ; Q1-390 ; Regional heritability ; prostate cancer ; infectious diseases ; MCMC ; combining studies screening ; conditional-logistic linkage ; Informatics ; autism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Sprache: Englisch
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  • 43
    Publikationsdatum: 2022-01-31
    Beschreibung: This eBook presents illustrative examples of genetic chaperonopathies affecting primarily nerves and muscles and discusses molecular mechanisms and treatment targeting chaperones, i.e., chaperonotherapy.
    Schlagwort(e): Q1-390 ; small-Hsp ; Hsp60/CCT/BBS ; Indirect/Secondary Chaperonopathies ; Genetic Chaperonopathies ; Hsp40/DnaJ ; chaperonotherapy
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 44
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Virus-caused asthma, we now call a phenotype of asthma. Regardless of the significance and popularity of this disease, the etiology of the virus-induced asthma have not well understood. In addition, a few effective vaccines have been applied to prevent respiratory virus infection. To solve the issues, it is essential to clarify and delineate both aspects of the virus and host defense systems including acute/chronic inflammation and airway tissue remodeling. To deeply review and discuss pathophysiology and epidemiology of virus-induced asthma, this topics includes new findings of the host immunity, pathology, epidemiology, and virology of asthma/chronic obstructive pulmonary disease (COPD). We believe that these works are well summarized and informative to glimpse the field of virus- associated asthma and COPD, and may help understanding the basic and clinical aspects of the diseases.
    Schlagwort(e): QR1-502 ; QK1-989 ; Q1-390 ; virus-induced asthma ; Pathology ; respiratory virus ; human immunity ; Epidemiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Sprache: Englisch
    Format: image/jpeg
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  • 45
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Transfer cells are anatomically specialized cells optimized to support high levels of nutrient transport in plants. These cells trans-differentiate from existing cell types by developing extensive and localized wall ingrowth labyrinths to amplify plasma membrane surface area which in turn supports high densities of membrane transporters. Unsurprisingly, therefore, transfer cells are found at key anatomical sites for nutrient acquisition, distribution and exchange. Transfer cells are involved in delivery of nutrients between generations and in the development of reproductive organs and also facilitate the exchange of nutrients that characterize symbiotic associations. Transfer cells occur across all taxonomic groups in higher plants and also in algae and fungi. Deposition of wall ingrowth-like structures are also seen in “syncytia” and “giant cells” which function as feeding sites for cyst and root-knot nematodes, respectively, following their infection of roots. Consequently, the formation of highly localized wall ingrowth structures in diverse cell types appears to be an ancient anatomical adaption to facilitate enhanced rates of apoplasmic transport of nutrients in plants. In some systems a role for transfer cells in the formation of an anti-pathogen protective barrier at these symplastic discontinuities has been inferred. Remarkably, the extent of cell wall ingrowth development at a particular site can show high plasticity, suggesting that transfer cell differentiation might be a dynamic process adapted to the transport requirements of each physiological condition. Recent studies exploiting different experimental systems to investigate transfer cell biology have identified signaling pathways inducing transfer cell development and genes/gene networks that define transfer cell identity and/or are involved in building the wall ingrowth labyrinths themselves. Further studies have defined the structure and composition of wall ingrowths in different systems, leading in many instances to the conclusion that this process may involve previously uncharacterized mechanisms for localized wall deposition in plants. Since transfer cells play important roles in plant development and productivity, the latter being relevant to crop yield, especially so in major agricultural species such as wheat, barley, soybean and maize, understanding the molecular and cellular events leading to wall ingrowth deposition holds exciting promise to develop new strategies to improve plant performance, a key imperative in addressing global food security. This Research Topic presents a timely and comprehensive treatise on transfer cell biology to help define critical questions for future research and thereby generating a deeper understanding of these fascinating and important cells in plant biology.
    Schlagwort(e): QK1-989 ; Q1-390 ; Wall ingrowth ; Arabidopsis thaliana ; synctial cells ; Zea mays ; transfer cells ; endosperm transfer cells ; Giant Cells ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Sprache: Englisch
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  • 46
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Research during the past decade highlights the strong link between appetitive feeding behavior, reward and motivation. Interestingly, stress levels can affect feeding behavior by manipulating hypothalamic circuits and brain dopaminergic reward pathways. Indeed, animals and people will increase or decrease their feeding responses when stressed. In many cases acute stress leads to a decrease in food intake, yet chronic social stressors are associated to increases in caloric intake and adiposity. Interestingly, mood disorders and the treatments used to manage these disorders are also associated with changes in appetite and body weight. These data suggest a strong interaction between the systems that regulate feeding and metabolism and those that regulate mood. This Research Topic aims to illustrate how hormonal mechanisms regulate the nexus between feeding behavior and stress. It focuses on the hormonal regulation of hypothalamic circuits and/or brain dopaminergic systems, as the potential sites controlling the converging pathways between feeding behavior and stress.
    Schlagwort(e): RC321-571 ; Q1-390 ; stress ; Obesity ; Dopamine ; Ghrelin ; Leptin ; Seasonal regulation ; feeding ; HPA axis ; Hypothalamus ; circadian rhythms ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 47
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-12-20
    Beschreibung: This Special Issue contains one review and five original articles, all of which address cutting-edge research in the field of water and environmental virology. The review article by Gerba and Betancourt summarizes the current status and future needs for the development of virus detection methods in water reuse systems, especially focusing on methods to assess the infectivity of enteric viruses. Original papers cover a variety of research topics, such as an environmental monitoring survey of group A rotaviruses in sewage and oysters in Japan, the occurrence and genetic diversity of noroviruses and rotaviruses in a wastewater reclamation system in China, the detection of viruses and their indicators in tanker water and its sources in Nepal, integrated culture next-generation sequencing to identify the diversity of F-specific RNA coliphages in wastewater, and the development of a portable collection and detection method for viruses from ambient air and its application to a wastewater treatment plant.
    Schlagwort(e): Q1-390 ; reuse ; aerosols ; viral indicator ; wastewater treatment ; microbial contamination ; index virus ; real-time PCR ; tanker water ; virus ; wastewater reclamation ; pathogenic virus ; infectivity ; chlorination ; molecular methods ; wastewater ; next-generation sequencing ; fecal source tracking ; oyster ; fecal-source marker ; viral contamination ; cell culture ; pathogenic microorganisms ; rotavirus ; ultraviolet disinfection ; F-specific RNA bacteriophage strain ; sewage ; waterborne gastroenteritis viruses ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Englisch
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  • 48
    Publikationsdatum: 2024-04-05
    Beschreibung: euromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
    Schlagwort(e): RC321-571 ; Q1-390 ; Informed Consent ; Deep Brain Stimulation ; Depression ; Neurosurgery ; Movement Disorders ; Neuromodulation ; Enhancement ; Neuroethics ; Philosophy ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 49
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: The integration of multisensory information is an essential mechanism in perception and in controlling actions. Research in multisensory integration is concerned with how the information from the different sensory modalities, such as the senses of vision, hearing, smell, taste, touch, and proprioception, are integrated to a coherent representation of objects. Multisensory integration is central for action control. For instance, when you grasp for a rubber duck, you can see its size and hear the sound it produces. Moreover, identical physical properties of an object can be provided by different senses. You can both see and feel the size of the rubber duck. Even when you grasp for the rubber duck with a tool (e.g. with tongs), the information from the hand, from the effect points of the tool and from the eyes are integrated in a manner to act successfully. Over the recent decade a surge of interest in multisensory integration and action control has been witnessed, especially in connection with the idea that multiple sensory sources are integrated in an optimized way. For this perspective to mature, it will be helpful to delve deeper into the information processing mechanisms and their neural correlates, asking about the range and constraints of this mechanisms, about its localization and involved networks.
    Schlagwort(e): BF1-990 ; Q1-390 ; recalibration ; haptic ; Human Information Processing ; Vision ; Perception ; reference frame ; Acoustics ; Tool Use ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 50
    Publikationsdatum: 2024-04-05
    Beschreibung: Volume I, entitled “Augmentation of Brain Functions: Brain-Machine Interfaces”, is a collection of articles on neuroprosthetic technologies that utilize brain-machine interfaces (BMIs). BMIs strive to augment the brain by linking neural activity, recorded invasively or noninvasively, to external devices, such as arm prostheses, exoskeletons that enable bipedal walking, means of communication and technologies that augment attention. In addition to many practical applications, BMIs provide useful research tools for basic science. Several articles cover challenges and controversies in this rapidly developing field, such as ways to improve information transfer rate. BMIs can be applied to the awake state of the brain and to the sleep state, as well. BMIs can augment action planning and decision making. Importantly, BMI operations evoke brain plasticity, which can have long-lasting effects. Advanced neural decoding algorithms that utilize optimal feedback controllers are key to the BMI performance. BMI approach can be combined with the other augmentation methods; such systems are called hybrid BMIs. Overall, it appears that BMI will lead to many powerful and practical brain-augmenting technologies in the future.
    Schlagwort(e): RC321-571 ; Q1-390 ; microcircuits ; Brain machine interface (BMI) ; nootropics ; tDCStranscranial direct current stimulation ; neural networks ; neuroprosthesis ; TMS ; implants ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 51
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-05-06
    Beschreibung: This reprint is devoted to “greener catalysis for environmental applications”, and primarily covers the catalytic synthesis of value-added chemicals, as well as the catalytic removal of pollutants. The most important topics covered were the conversion of waste to the product, solvent-free conditions as well as toxicity assessment of the reaction products.
    Schlagwort(e): selectivity tuning ; CO2 methanation ; reverse water gas shift ; photocatalysis ; dye ; UV ; peroxydisulfate ; advanced oxidation process ; Fischer-Tropsch ; jet fuel ; gasoline ; CoMn ; hydrotalcite-like precursors ; heterogeneous catalysis ; montmorillonite ; benzimidazoles ; gallium ; vanadium ; hydrodesulfurization ; hydrogenation ; synthesis method ; catalysis ; zero valent iron ; de-chlorination ; borohydride ; sol-gel ; ferromagnetic ; glycine–nitrate process ; copper-based nanoparticles ; photocatalysis activity ; NP9EO ; Fenton degradation ; ofloxacin ; Fe3O4 ; zeolite ; heterogeneous ; ion exchange resins ; waste cooking oil ; reuse of catalyst ; epoxidation ; Circular Economy ; contaminants of emerging concern ; advanced oxidation processes ; by-products ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
    Sprache: Englisch
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  • 52
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-12-06
    Beschreibung: Vegetable crops provide valuable minerals and vitamins that are indispensible for human health. Scientists have been working on the genetics of vegetable crops, deciphering the molecular bases of agronomically important traits. These genetic bases and variations in vegetable traits will greatly facilitate vegetable genetic improvement. Therefore, the genes of and genetic research on vegetable crops are of great importance. This Special Issue is a collection of 13 important research papers addressing the genes, genetics, and breeding of major vegetable crops. In the present book, the authors described the genes and QTLs responsible for stress tolerance, disease resistance, vegetable yield, and quality. The 13 research papers cover germplasm enhancement and evaluation, QTL mapping, gene isolation, marker development, and gene expression as well as gene editing in a wide range of vegetable species, including broccoli, pepper, eggplant, onion, and Cucurbita species. Readers from all over the globe are expected to greatly benefit from this Special Issue collection regarding their own work and the goal of improving breeding efficiency with molecular breeding to generate environment-adaptive, high-yield, and high-quality vegetable crops with which to feed the global population of 9.7 billion in an extreme climate by 2050.
    Schlagwort(e): pepper ; Capsicum annuum ; Phytophthora capsici ; high-density genetic map ; QTL ; Capcicum annuum L. ; RNA-Seq ; nitrogen-use efficiency ; low-nitrogen tolerance ; CaHSP18.1a ; gene silencing ; transgenic Arabidopsis ; heat stress ; gene expression ; pumpkin ; simple sequence repeat (SSR) ; syntenic relationship ; cross-species markers ; population structure ; eggplant ; heat shock factor (Hsf) ; heat shock protein (Hsp) ; thermotolerance ; C. frutescens ; SSR ; germplasm ; genetic diversity ; CRISPR/Cas ; gene knockout ; genome editing ; germplasm resource ; precision editing ; regulatory framework ; trait improvement ; Brassica oleracea ; broccoli ; candidate gene ; anthocyanin ; allelochemicals ; VOCs properties ; VOCs action ; VOCs detection ; green agriculture ; progress ; genetic researches ; molecular breeding ; transcriptomics ; transcription factor ; heritability ; genetic advance ; multi-trait selection ; principal component analysis ; HRM ; molecular marker ; phylogenetic analysis ; RNA sequencing ; SCAR ; SNP ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
    Sprache: Englisch
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  • 53
    Publikationsdatum: 2024-04-05
    Beschreibung: Photosystem II is a 700-kDa membrane-protein super-complex responsible for the light-driven splitting of water in oxygenic photosynthesis. The photosystem is comprised of two 350-kDa complexes each made of 20 different polypeptides and over 80 co-factors. While there have been major advances in understanding the mature structure of this photosystem many key protein factors involved in the assembly of the complex do not appear in the holoenzyme. The mechanism for assembling this super-complex is a very active area of research with newly discovered assembly factors and subcomplexes requiring characterization. Additionally the ability to split water is inseparable from light-induced photodamage that arises from radicals and reactive O2 species generated by Photosystem II chemistry. Consequently, to sustain water splitting, a “self repair” cycle has evolved whereby damaged protein is removed and replaced so as to extend the working life of the complex. Understanding how the biogenesis and repair processes are coordinated is among several important questions that remain to be answered. Other questions include: how and when are the inorganic cofactors inserted during the assembly and repair processes and how are the subcomplexes protected from photodamage during assembly? Evidence has also been obtained for Photosystem II biogenesis centers in cyanobacteria but do these also exist in plants? Do the molecular mechanisms associated with Photosystem II assembly shed fresh light on the assembly of other major energy-transducing complexes such as Photosystem I or the cytochrome b6/f complex or indeed other respiratory complexes? The contributions to this Frontiers in Plant Science Research Topic are likely to reveal new details applicable to the assembly of a range of membrane-protein complexes, including aspects of self-assembly and solar energy conversion that may be applied to artificial photosynthetic systems. In addition, a deeper understanding of Photosystem II assembly — particularly in response to changing environmental conditions — will provide new knowledge underpinning photosynthetic yields which may contribute to improved food production and long-term food security.
    Schlagwort(e): QK1-989 ; Q1-390 ; Arabidopsis thaliana ; photoactivation ; photosynthesis ; Chlamydomonas reinhardtii ; cyanobacteria ; biogenesis ; Photosystem II ; photodamage ; Nicotiana tabacum ; Synechocystis sp. PCC 6803 ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Sprache: Englisch
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  • 54
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Big data is revolutionizing our ability to measure and study the human brain. New technology increases the resolution of images that are being study as well as enables researchers to study the brain as it functions. These technological advances are combined with efforts to collect neuroimaging data on large numbers of subjects, in some cases longitudinally. This combination of advances in measurement and scope of studies requires novel development in the statistical analysis. Fast, scalable, robust and accurate models and approaches need to be developed to make headway on these problems. This volume represents a unique collection of researchers providing deep insights on the statistical analysis of big neuroimaging data.
    Schlagwort(e): RC321-571 ; Q1-390 ; fMRI ; Neuroscience ; functional connectivity ; EEG ; Classification ; prediction ; big data ; MEG ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 55
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: A conversation between two people can only take place if the words intended by each speaker are successfully recognized. Spoken word recognition is at the heart of language comprehension. This automatic and smooth process remains a challenge for models of spoken word recognition. Both the process of mapping the speech signal onto stored representations for words, and the format of the representation themselves are subject to debate. So far, existing research on the nature of spoken word representations has focused mainly on native speakers. The picture becomes even more complex when looking at spoken word recognition in a second language. Given that most of the world’s speakers know and use more than one language, it is crucial to reach a more precise understanding of how bilingual and multilingual individuals encode spoken words in the mental lexicon, and why spoken word recognition is more difficult in a second language than in the native language. Current models of native spoken word recognition operate under two assumptions: (i) that listeners’ perception of the incoming speech signal is optimal; and (ii) that listeners’ lexical representations are accurate. As a result, lexical representations are easily activated, and intended words are successfully recognized. However, these assumptions are compromised when applied to a later-learned second language. For a variety of reasons (e.g., phonetic/phonological, orthographic), second language users may not perceive the speech signal optimally, and they may still be refining the motor routines needed for articulation. Accordingly, their lexical representations may differ from those of native speakers, which may in turn inhibit their selection of the intended word forms. Second language users also have to solve a larger selection challenge—having words in more than one language to choose from. Thus, for second language users, the links between perception, lexical representations, orthography, and production are all but clear. Even for simultaneous bilinguals, important questions remain about the specificity and interdependence of their lexical representations and the factors influencing cross-language word activation. This Frontiers Research Topic seeks to further our understanding of the factors that determine how multilinguals recognize and encode spoken words in the mental lexicon, with a focus on the mapping between the input and lexical representations, and on the quality of lexical representations.
    Schlagwort(e): BF1-990 ; Q1-390 ; Phonological knowledge ; Second-language speech ; bilingual and bidialectal lexicon ; spoken word recognition ; lexical access ; orthographic knowledge ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 56
    Publikationsdatum: 2024-03-31
    Beschreibung: This forum of comprehensive reviews and research studies on distinct aspects of the pathophysiology of BAV aortopathy provides both the state of the art in the knowledge on this complex disease and novel insights into its causes and consequences. The present collection of focused papers also envisions and proposes new therapeutic strategies, novel biomarkers and original risk stratification criteria, for the improvement of patient management.
    Schlagwort(e): QP1-981 ; Q1-390 ; smooth muscle cells ; microRNAs ; aortic root ; endothelial cells ; aortic surgery ; bicuspid aortic valve ; 4DFlow analysis ; aortopathy ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Sprache: Englisch
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  • 57
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: This research topic stems from the "Interdisciplinary Approaches to Multilingualism" conference, which was hosted by the Language Research Centre at the University of Calgary. It was the first conference of its kind, which brought together the work of researchers, educators, and policy makers in the areas of first and second language acquisition from psycholinguistic and pedagogical perspectives. The goal was to provide an opportunity for participants to engage with the implications of multilingualism from a range of perspectives, including the effects of being bilingual from infancy to adulthood, the process and benefits of learning multiple languages, and the impact of multilingualism on society.
    Schlagwort(e): BF1-990 ; Q1-390 ; Developmental psycholinguistics ; second language literacy development ; Multilingualism ; psycholinguistic research methods ; Second language pedagogy ; bilingualism ; Second Language Acquisition ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 58
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 59
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: In the last decade, sleep spindles have attracted steadily increasing attention. This interest is motivated by the many intriguing relationships between spindles and various diseases (e.g., schizophrenia, Parkinson, Alzheimer, autism, mental retardation), recovery processes (e.g., post brain stroke), and cognitive faculties (e.g., memory consolidation, intelligence, dream recall, sleep preservation). Nonetheless, a methodological wall has impeded the study of sleep spindles. Their investigation rests heavily on our ability to reliably and consistently identify spindle patterns from background EEG activity, a task involving many obstacles, including: a fuzzy definition of spindles, low inter-expert agreement on their scoring, lack of consensus on standard techniques for their automated detection, low reproducibility of observed characteristics and correlates, unavailability of large, standardized, high-quality databases, and inconsistencies in the methods used to evaluate the performance of automated detectors. The primary aims of this research topic were to bring together world-class researchers on a project designed to facilitate exchanges on methodological difficulties encountered in assessing sleep spindles and to promote standardized spindle-related resources. In preparing their contributions, authors were encouraged to use existing – or to propose new – publicly available resources for assessing sleep spindles. To allow fair and accurate comparison of reported results, the authors were also encouraged to validate their tools on a common benchmark. A database containing expert spindle scoring (i.e., the Montreal Archive of Sleep Studies) was made publicly available for that purpose.
    Schlagwort(e): RC321-571 ; Q1-390 ; Neural oscillations ; Electroencephalography (EEG) ; Sleep ; Sleep Spindles ; Memory ; IQ ; sigma waves ; automatic detection ; biomarker ; Open access ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 60
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    Frontiers Media SA
    Publikationsdatum: 2024-03-31
    Beschreibung: Energy metabolism is central to life and altered energy expenditure (EE) is often cited as a central mechanism responsible for development of the obese phenotype. Resting EE, EE of physical activity, cold induced thermogenesis and thermic effect of feeding add to produce total EE but can also affect each other. It is thus very important that each component be well measured. Measuring energy expenditure by indirect calorimetry is extremely simple in theory but the practice if far more difficult. Taking into account temperature in small sized animals, measuring accurately the effect of activity on EE, correcting EE for body size body composition, age sex etc… add difficulties in producing reliable data. The goal of this Research Topic was to call for the practical experience of main investigators trained to practice calorimetry in order to get their feedback and the way they deal with the various and specific problems of humans and animal calorimetry. The goal is to share the questions/solutions experienced by the contributors to inititate a “guide of the good practices” that can be periodically updated and used by all those who are and will be interested in measuring energy metabolism from the 20g mouse to the human and large farm animals.
    Schlagwort(e): QP1-981 ; Q1-390 ; Body Composition ; Thermogenesis ; brown adipose tissue ; Body Size ; Energy Expenditure ; indirect calorimetry ; physical activity ; metabolic Phenotyping ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Sprache: Englisch
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  • 61
    Publikationsdatum: 2023-12-20
    Beschreibung: Landscapes have long been viewed as ‘multifunctional’, integrating ecological, economic, sociocultural, historical, and aesthetic dimensions. Landscape science and public awareness in Europe have been progressing in leaps and bounds. The challenges involved in landscape-related issues and fields, however, are multiple and refer to landscape stewardship and protection, as well as to the development of comprehensive theoretical and methodological approaches, in tandem with public sensitization and participatory governance and in coordination with appropriate top-down planning and policy instruments. Landscape-scale approaches are fundamental to the understanding of past and present cultural evolution, and are now considered to be an appropriate spatial framework for the analysis of sustainability. Methods and tools of landscape analysis and intervention have also gone a long way since their early development in Europe and the United States. Although significant progress has been made, there remain many issues which are understudied or not investigated at all—at least in a Mediterranean context. This Special Issue addresses the application of landscape theory and practice in the Eastern Mediterranean and mainly, but not exclusively, reports on the outcomes of an international conference held in Jordan, in December 2015, with the title “Landscapes of Eastern Mediterranean: Challenges, Opportunities, Prospects and Accomplishments”. The focus of this Special Issue, landscapes of the Eastern Mediterranean region, thus constitutes a timely area of research interest, not only because these landscapes have so far been understudied, but also as a rich site of strikingly variegated, long-standing multicultural human–environmental interactions. These interactions, resting on and taking shape through millennia of continuity in tradition, have been striving to adapt to technological advances, while currently juggling with manifold and multilayered socioeconomic and climate–environmental crises.
    Schlagwort(e): G1-922 ; Q1-390 ; n/a ; landscape archaeology ; Cyprus ; Landscape Character Assessment (LCA) ; Eastern Mediterranean ; Land Description Units ; stakeholders’ analysis ; UK ; local authority ; ancient sanctuaries ; East Med landscape ; Twain-born Border Lord ; Landscape Decision Support System ; mapping ; topography ; Byzantine landscape and garden art ; economy ; LCA ; classification ; churches ; Arabic-speaking ; participatory ; Landscape Risk Assessment Model ; landforms ; GIS ; planning ; typology ; Greek-speaking ; public realm ; landscape changes ; sacred space ; comparative study ; urban environment ; ideology ; political power ; Arabic landscape and garden art ; cultural sustainability ; historical maps ; religion ; rural land ; multi-functional landscapes ; Lebanon ; Mediterranean ; geographical information system ; spatial distributions ; Land Description Unit (LDU) ; political sustainability ; landscape ; landscape character assessment ; governance ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
    Sprache: Englisch
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  • 62
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-03-07
    Beschreibung: Metal 3D printing, as an advanced forming, can manufacture parts directly from digital model by using layer by layer material build-up approach. This manufacturing method can prepare complex shape metal parts in short time, with and high precision. Three-dimensional printing processes can be classified into two major groups: Powder Bed Fusion-based technologies and Directed Energy Deposition. Three-dimensional printing features freedom of part complexity, part design, and light-weighting for aerospace, automobile, and other industries application. The Global Metal 3D Printing Market is mainly driven by the the fast developing of aerospace and automobile industry. The Global Metal 3D Printing Market size was valued at USD 534.18 Million in 2020 and is projected to reach USD 4458.76 Million by 2028, growing at a CAGR of 30.38% from 2021 to 2028.
    Schlagwort(e): 17-4PH ; SLM ; solution temperature ; microstructure and properties ; selective laser melting ; CuCrZr alloy ; process parameters ; relative density ; tensile properties ; Ni-based superalloys ; electron beam melting ; additive manufacturing ; Argon gas atomized ; plasma rotation electrode process ; powder characteristics ; residual stresses ; selective laser melting (SLM) ; finite element modeling (FEM) ; triply periodic minimal surface (TPMS) ; copper corrosion ; liquefied petroleum gas ; H2S corrosion ; SEM ; XPS ; CLF-1 steel ; microstructure ; mechanical properties ; in-situ alloying ; composition inhomogeneity ; computer simulation ; processing map ; laser powder bed fusion ; graphene ; high temperature ; mechanical property ; alumina ; cobalt-chromium-molybdenum alloy ; electroless plating ; friction performance ; implants ; Laser Powder Bed Fusion ; defects ; process parameter ; powder bed fusion ; surface roughness ; porosity ; residual stress ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
    Sprache: Englisch
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  • 63
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-03-07
    Beschreibung: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Schlagwort(e): 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Sprache: Englisch
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  • 64
    Publikationsdatum: 2023-12-21
    Beschreibung: Aflatoxins are a group of polyketide mycotoxins that are produced mainly by members of the genus Aspergillus. Production of these toxic secondary metabolites is closely related to fungal development (Keller et al., 2005; Jamali et al., 2012). Contamination of food, feed and agricultural commodities by aflatoxins poses enormous economic and serious health concerns because these chemicals are highly carcinogenic and can directly influence the structure of DNA. The resulting genetic defects can lead to fetal misdevelopment and miscarriages; aflatoxins are also known to suppress immune systems (Razzaghi-Abyaneh et al., 2013). In a global context, aflatoxin contamination is a constant concern between the 35N and 35S latitude where developing countries are mainly situated. With expanding boundaries of developing countries, aflatoxin contamination has become a persistent problem to those emerging areas (Shams-Ghahfarokhi et al., 2013). The continuing threat by aflatoxin contamination of food, feed and agricultural commodities to the world population has made aflatoxin research one of the most exciting and rapidly developing study areas of microbial toxins. The present research topic includes six review articles, three mini reviews and four original research articles. Contributors highlight current global health issues arising from aflatoxins and aflatoxigenic fungi and cover important aspects of aflatoxin research including contamination of crops, epidemiology, molecular biology and management strategies. Special attention is given to fungus-plant host interactions, biodiversity and biocontrol, sexual recombination in aflatoxigenic aspergilli, potential biomarkers for aflatoxin exposure in humans and safe storage programs.
    Schlagwort(e): R5-920 ; QR1-502 ; Q1-390 ; TX341-641 ; genetic diversity ; Public Health ; Aspergillus flavus ; Genomics ; MicroRNAs ; Fungus host interactions ; biological control ; aflatoxin ; agricultural crops ; bic Book Industry Communication::M Medicine
    Sprache: Englisch
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  • 65
    Publikationsdatum: 2024-04-05
    Beschreibung: Helicases are the proteins that bind to double- or single-stranded DNA and/or RNA chains to unwind higher order structures, usually consuming energy from the hydrolysis of ATP molecules. The biological roles of helicases are associated with a variety of DNA and/or RNA metabolisms, including DNA-replication, -repair, -recombination, RNA processing, and transcription. Dysfunctions of helicases cause various diseases, such as xeroderma pigmentosum (XP), premature aging syndrome, cancer and immunodeficiency, in humans. Moreover, recent genetic analyses revealed that mutations in helicase-encoding genes are frequently found in patients of specific diseases. Some helicases regulate cellular senescence by controlling integrity of genomes, and others play a role in neuromuscular functions presumably by modulating processing of mRNAs. However, the molecular mechanisms of how helicases are regulated in order to maintain our health are not yet fully understood. In this research topic, we will focus on the expression and functions of helicases and their encoding genes, reviewing recent research progresses that provide new insights into development of clinical and pharmaceutical treatments targeting helicases.
    Schlagwort(e): QH426-470 ; Q1-390 ; DNA Repair ; Aging ; helicases ; Telomere ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Sprache: Englisch
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  • 66
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-12-20
    Beschreibung: The practical importance of economic valuation information can hardly be overstated. Coastal and marine resource policy planning and management benefit from complete information on the impact of policy decisions.
    Schlagwort(e): Q1-390 ; internet survey ; open access ; contingent valuation method ; coastal management ; tourism ; Thailand ; marine ; wetlands ; harmful algae blooms ; environmental valuation ; quota ; cyanobacteria ; estuarine and coastal ecosystems ; wealth accounting ; seawater quality ; economic analysis ; remote sensing ; ecosystem restoration ; coastal ecosystems ; random utility model ; contingent behavior ; public policy ; habitat–fishery linkages ; Barbados ; coastal ecosystem services valuation ; fishery ; mangroves ; ecosystem services valuation ; coral reefs valuation ; recreational boating ; regulated open access ; non-market value ; economic valuation ; ecosystem services ; coastal ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 67
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 68
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: The visual system consists of hierarchically organized distinct anatomical areas functionally specialized for processing different aspects of a visual object (Felleman & Van Essen, 1991). These visual areas are interconnected through ascending feedforward projections, descending feedback projections, and projections from neural structures at the same hierarchical level (Lamme et al., 1998). Accumulating evidence from anatomical, functional and theoretical studies suggests that these three projections play fundamentally different roles in perception. However, their distinct functional roles in visual processing are still subject to debate (Lamme & Roelfsema, 2000). The focus of this Research Topic is the roles of feedforward and feedback projections in vision. Even though the notions of feedforward, feedback, and reentrant processing are widely accepted, it has been found difficult to distinguish their individual roles on the basis of a single criterion. We welcome empirical contributions, theoretical contributions and reviews that fit into any one (or a combination) of the following domains: 1) their functional roles for perception of specific features of a visual object 2) their contributions to the distinct modes of visual processing (e.g., pre-attentive vs. attentive, conscious vs. unconscious) 3) recent techniques/methodologies to identify distinct functional roles of feedforward and feedback projections and corresponding neural signatures. We believe that the current Research Topic will not only provide recent information about feedforward/feedback processes in vision but also contribute to the understanding fundamental principles of cortical processing in general.
    Schlagwort(e): BF1-990 ; Q1-390 ; projections ; processes ; Feedback ; Vision ; feedforward ; Visual System ; mechanisms ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 69
    Publikationsdatum: 2024-04-05
    Beschreibung: The eBook "Building Strategies for Porcine Cancer Models" presents a series of articles demonstrating the state-of-the-art developments in pig models for cancer research. Renowned researchers dedicated to the reproduction, genomic and biological engineering of the pig model for biomedicine contribute to this special research area. Although advances in these areas are occurring at surprising speeds, they are still far from realizing all the potential benefits that this biological model could provide to science. The current biomedical models may limit the frontier of knowledge in the cancer research.
    Schlagwort(e): QH426-470 ; Q1-390 ; Pigs ; Cloning ; Genetic engineering ; Comparative Genomics ; Gene Editing ; Animal Models ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Sprache: Englisch
    Format: image/jpeg
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  • 70
    Publikationsdatum: 2024-04-05
    Beschreibung: This e-book summarizes recent advances in the young and rapidly developing field of microbial volatiles. Articles included here reveal novel information about the chemical diversity of bacterial and fungal volatiles, their functions, their roles in inter-specific and inter-kingdom interactions and the metabolic and physiological changes their exposure causes in the target organisms. The e-book is divided in three chapters: (1) Natural Functions of Microbial Volatiles; (2) Volatile Production and Ecosystem Functioning and (3) Volatile Detection and Identification.
    Schlagwort(e): QR1-502 ; Q1-390 ; microorganisms ; infochemicals ; natural functions ; induced systemic resistance ; Plants ; antimicrobials ; plant growth promotion ; volatiles ; interactions ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Sprache: Englisch
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  • 71
    Publikationsdatum: 2024-04-05
    Beschreibung: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 72
    Publikationsdatum: 2023-12-20
    Beschreibung: In this eBook, Conceptual Categories and the Structure of Reality, the title very well describes the book's content. Within the book's pages a selection of academics from a variety of human behaviour, human/social science and humanities disciplines write about their research all of which can be typified by their consideration of how categories are used to structure understanding of phenomena. These authors have considered how reality may be understood through notions such as categorial and structural ontologies, part-whole relatoinships (mereology), the qualitative, quantitative and philosophical use of the facet theory approach to research, mapping sentences and declarative mapping sentence, hermeneutics, concepts and constructs, similarities and differences. The resulting collection presents the foregoing conceptual and empirical approaches to knowledge development in general (chapter 1&3 Hackett); Phillips and Wislons' review of compositional syntax in bird calls (chapter 2); neurobehavioral decision systems (chapter 4 Foxall); representations of human psychological processes (chapter 5 Juan-Miguel López-Gil; Rosa Gil; Roberto García); free associations mirroring and its relation to self- and world-related concepts (chapter 6 Martin Kuška; Radek Trnka; Aleš Antonín Kuběna; Jiří Růžička); local knowledge and going beyond the data (chapter 7 Steven Phillips); categorical etiologies of speech sound disorders (chapter 8 Kelly Farquharson); similarity of visual appearance (chapter 9 Nao Nakatsuji; Hisayasu Ihara; Takeharu Seno; Hiroshi Ito); and a consideration of the seminal writing of David Oderberg's on the categorial classification of reality (chapter 10 Hackett).
    Schlagwort(e): BF1-990 ; Q1-390 ; mereology ; similarities ; hermeneutics ; concepts ; category ; ontology ; facet theory ; declarative mapping sentence ; bic Book Industry Communication::J Society & social sciences::JM Psychology
    Sprache: Englisch
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  • 73
    Publikationsdatum: 2023-12-20
    Beschreibung: Foram identificados 4.490 indivíduos incluindo 17 ordens, 68 famílias e 160 espécies de peixes nos estágios de larvas e juvenis. Foram elaborados textos com informações gerais das ordens e famílias, descrição das principais características das espécies, fotografias dos diferentes estágios de desenvolvimento, georeferrenciamento, habitat da espécie, nome vulgar e as referências utilizadas para a identificação.
    Schlagwort(e): Q1-390 ; SCIENCE ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Portugiesisch
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  • 74
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-08-12
    Beschreibung: Silica and silicon-based nanostructures are now well-understood materials for which the technologies are mature. The most obvious applications, such as electronic devices, have been widely explored over the last two decades. The aim of this Special Issue is to bring together the state of the art in the field and to enable the emergence of new ideas and concepts for silicon and silica-based nanostructures.
    Schlagwort(e): maize ; NPK ; SiO2-NPs ; productivity ; fertilizer ; mineral ; weevils ; LC50 ; toxicity ; mesoporous silica ; nanomaterials ; desulfurization ; fuel ; JP-8 ; black silicon ; light absorption enhanced ; micro-nano manufacturing ; nanometer surface ; nano-silica ; tricalcium aluminate ; pozzolanic reaction ; C-A-S-H gel ; silicon nanoparticles ; silicon nanowires ; synthesis ; high energy density ; lithium-ion batteries ; high-capacity anode ; VLS ; laser pyrolysis ; size effect ; shape effect ; biomass rice husk ; silicon ; nanocrystals ; luminescence ; high porosity ; pH sensor ; temperature sensor ; dual sensor ; metal-assisted chemical etching ; Si nanostructures ; high aspect ratio ; zone plate ; silicon nanowire ; nanowire array ; silicon anode ; n-type silicon anode ; Li-ion battery ; nanowires ; nanonets ; transistor ; integration process ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 75
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-11-17
    Beschreibung: This Special Issue provides a collection of recent research and reviews that investigate many areas of welfare assessment, such as novel approaches and technologies used to evaluate the welfare of farmed, captive, or wild animals. Research in this Special Issue includes welfare assessment related to pilot whales, finishing pigs, commercial turkey flocks, and dairy goats; the use of sensors or wearable technologies, such as heart rate monitors to assess sleep in dairy cows, ear tag sensors, and machine learning to assess commercial pig behaviour; non-invasive measures, such as video monitoring of behaviour, computer vision to analyse video footage of red foxes, remote camera traps of free-roaming wild horses, infrared thermography of effort and sport recovery in sport horses; telomere length and regulatory genes as novel biomarkers of stress in broiler chickens; the effect of environment on growth physiology and behaviour of laboratory rare minnows and housing system on anxiety, stress, fear, and immune function of laying hens; and discussions of natural behaviour in farm animal welfare and maintaining health, welfare, and productivity of commercial pig herds.
    Schlagwort(e): bioethics ; domestication ; genetic selection ; animal behavior ; animal welfare ; eye caruncle temperature ; Spanish Sport Horse ; performance test ; genetic lines ; heritability ; infrared thermography ; pigs ; welfare ; health ; herd management ; monitoring technologies ; animal husbandry ; welfare assessment ; wellbeing ; goat ; caprine ; dairy ; dairy cows ; heart rate ; sleep ; heart rate variability ; polysomnography ; animal-based welfare indicators ; camera traps ; wild horses ; precision swine farming ; ear tag pig sensor ; behavioral monitoring ; machine intelligence ; technology adoption ; broiler ; corticosterone ; performance ; telomeres ; telomere regulators ; stress biomarkers ; horse ; equine ; lying ; time budget ; locomotion ; geriatric ; orthopedic ; recumbency ; mixed commercial turkey flocks ; on-farm assessment ; YOLOv4 ; computer vision ; animal monitoring ; animal activity ; body posture ; rare minnow ; environmental enrichment ; growth ; physiology ; anxiety-like behavior ; enrichment ; hospitalization requirement ; lameness ; lesions ; tail biting ; attention bias ; conventional cage ; environmental complexity ; feather corticosterone ; IgA ; laying hen ; animal welfare assessment ; behaviour ; human intervention ; marine mammal ; cetacean ; management ; stranding ; wildlife ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Sprache: Englisch
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  • 76
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: Foreword by Richard J. Stevenson, Macquarie University (Australia): It was long thought that the human nose might be able to discriminate somewhere in the order of 10,000 different odourants. The recent finding that the human nose can discriminate something like a trillion different smells serves as yet another reminder that we have again underestimated the capacity of our sense of smell (Bushdid, Magnasco, Vosshall & Keller, 2014). This volume serves as a further corrective for anyone who should hold the view that olfaction is unimportant in human affairs. The papers presented in this ebook, carefully collated and overseen by Aldo Zucco, Benoist Schaal, Mats Olsson and Ilona Croy, showcase a large number of quite different reasons for studying the applied side of olfaction, and indeed human olfaction in general. The 23 contributions presented here cover a broad range of topics, which illustrate contemporary interests in our field. Although with a strong applied focus, a noteworthy feature of this ebook is the richness of the theoretical perspectives that are developed. These range from considerations of olfactory perception, memory, expertise, and priming right the way through to receptor genetics. These contributions, from many leading experts in the field, will surely shape much of the applied work linking olfaction to disease, which is a further focus of this ebook. In respect to health and disease, the chapters on aging, pregnancy, depression, alcohol dependency and environmental odours, present overviews and rich new data on many contemporary problems, to which the study of olfaction is now contributing. A particularly notable aspect of olfactory experience is the affective impact that odours can have on people and their lives. The ebook covers some particularly intriguing aspects of work in this area, with empirical studies investigating dissociations between wanting and liking, stress reduction in the elderly, mother-infant bonding, and the emotions that different odourants can evoke. This affective line of work is nicely complemented by empirical studies on expertise, the effect of odours on visual attention, and the relationship between particular personality traits and interest in olfaction. The gradual appropriation of methods from cognitive neuroscience into olfaction is also nicely represented in this ebook, with at least three of the chapters reporting data using neuroimaging, including a particular intriguing study looking at recognition of odours in mixtures. Finally, the close links between olfactory perception and sensory evaluation are also reflected in a chapter on wine. I hope that readers of this e-book will be struck, as I have been in reading its various chapters, how much olfaction affects our lives, and how the study of this sense can enrich it.
    Schlagwort(e): BF1-990 ; Q1-390 ; Disease ; Health ; Everyday Life ; Cognition ; Applied olfaction ; Expertise ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 77
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-01-31
    Beschreibung: This edition is a reprint of the Special Issue published online in the open access journal Remote Sensing (ISSN 2072-4292) from 2016–2017 (available at: http://www.mdpi.com/journal/remotesensing/special issues/rsALS), complemented by selected articles published in Remote Sensing
    Schlagwort(e): G1-922 ; Q1-390 ; Airborne Lidar Systems ; Data Processing
    Sprache: Englisch
    Format: image/png
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  • 78
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Women drinking during pregnancy can result in Fetal Alcohol Spectrum Disorder (FASD), which may feature variable neurodevelopmental deficits, facial dysmorphology, growth retardation, and learning disabilities. Research suggests the human brain is precisely formed through an intrinsic, genetic-cellular expression that is carefully orchestrated by an epigenetic program. This program can be influenced by environmental inputs such as alcohol. Current research suggests the genetic and epigenetic elements of FASD are heavily intertwined and highly dependent on one another. As such, now is the time for investigators to combine genetic, genomic and epigenetic components of alcohol research into a centralized, accessible platform for discussion. Genetic analyses inform gene sets which may be vulnerable to alcohol exposure during early neurulation. Prenatal alcohol exposure indeed alters expression of gene subsets, including genes involved in neural specification, hematopoiesis, methylation, chromatin remodeling, histone variants, eye and heart development. Recently, quantitative genomic mapping has revealed loci (QTLs) that mediate alcohol-induced phenotypes identified between two alcohol-drinking mouse strains. One question to consider is (besides the role of dose and stage of alcohol exposure) why only 5% of drinking women deliver newborns diagnosed with FAS (Fetal Alcohol Syndrome)? Studies are ongoing to answer this question by characterizing genome-wide expression, allele-specific expression (ASE), gene polymorphisms (SNPs) and maternal genetic factors that influence alcohol vulnerability. Alcohol exposure during pregnancy, which can lead to FASD, has been used as a model to resolve the epigenetic pathway between environment and phenotype. Epigenetic mechanisms modify genetic outputs through alteration of 3D chromatin structure and accessibility of transcriptional machinery. Several laboratories have reported altered epigenetics, including DNA methylation and histone modification, in multiple models of FASD. During development DNA methylation is dynamic yet orchestrated in a precise spatiotemporal manner during neurulation and coincidental with neural differentiation. Alcohol can directly influence epigenetics through alterations of the methionine pathway and subsequent DNA or histone methylation/acetylation. Alcohol also alters noncoding RNA including miRNA and transposable elements (TEs). Evidence suggests that miRNA expression may mediate ethanol teratology, and TEs may be affected by alcohol through the alteration of DNA methylation at its regulatory region. In this manner, the epigenetic and genetic components of FASD are revealing themselves to be mechanistically intertwined. Can alcohol-induced epigenomic alterations be passed across generations? Early epidemiological studies have revealed infants with FASD-like features in the absence of maternal alcohol, where the fathers were alcoholics. Novel mechanisms for alcohol-induced phenotypes include altered sperm DNA methylation, hypomethylated paternal allele and heritable epimutations. These studies predict the heritability of alcohol-induced epigenetic abnormalities and gene functionality across generations. We opened a forum to researchers and investigators the field of FASD to discuss their insights, hypotheses, fresh data, past research, and future research themes embedded in this rising field of the genetics and epigenetics of FASD. This eBook is a product of the collective sharing and debate among researchers who have contributed or reviewed each subject.
    Schlagwort(e): QH426-470 ; QH301-705.5 ; Q1-390 ; DNA Methylation ; Fetal Alcohol Syndrome ; histone modification ; Epigenetic medicine ; Genomics ; Alcoholism ; transgenerational ; Pregnancy drinking ; FASD ; Gene environmental interaction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Sprache: Englisch
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  • 79
    Publikationsdatum: 2024-04-05
    Beschreibung: The brain of each animal shows specific traits that reflect its phylogenetic history and its particular lifestyle. Therefore, comparing brains is not just a mere intellectual exercise, but it helps understanding how the brain allows adaptive behavioural strategies to face an ever-changing world and how this complex organ has evolved during phylogeny, giving rise to complex mental processes in humans and other animals. These questions attracted scientists since the times of Santiago Ramon y Cajal one of the founders of comparative neurobiology. In the last decade, this discipline has undergone a true revolution due to the analysis of expression patterns of morphogenetic genes in embryos of different animals. The papers of this e-book are good examples of modern comparative neurobiology, which mainly focuses on the following four Grand Questions: a) How are different brains built during ontogeny? b) What is the anatomical organization of mature brains and how can they be compared? c) How do brains work to accomplish their function of ensuring survival and, ultimately, reproductive success? d) How have brains evolved during phylogeny? The title of this e-book, Adaptive Function and Brain Evolution, stresses the importance of comparative studies to understand brain function and, the reverse, of considering brain function to properly understand brain evolution. These issues should be taken into account when using animals in the research of mental function and dysfunction, and are fundamental to understand the origins of the human mind.
    Schlagwort(e): RC321-571 ; Q1-390 ; comparative neurobiology ; brain evolution ; phylogeny ; ontogeny ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 80
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-12-20
    Beschreibung: Satellite Earth observation (EO) data have already exceeded the petabyte scale and are increasingly freely and openly available from different data providers. This poses a number of issues in terms of volume (e.g., data volumes have increased 10
    Schlagwort(e): G1-922 ; Q1-390 ; knowledge base ; metadata ; Synthetic Aperture Radar ; versioning ; web services ; web application ; sustainable development goals ; earth observations ; FAIR principles ; land cover classification ; semantic enrichment ; satellite imagery ; imagery ; analysis ; information extraction ; ARD ; analysis ready data ; swiss DC ; data cube ; Open Data Cube ; UN 2030 Agenda for Sustainable Development ; time-series ; graph data ; Digital Earth Australia ; query store ; open data cube ; pyroSAR ; R ; earth oberservation ; image cube ; sentinel ; open science ; Sentinel ; reproducibility ; change ; big EO data ; earth observation ; big Earth data ; Earth Observations ; Australia ; geospatial standards ; big earth data ; visualization ; UN System of Environmental Economic Accounting ; interferometric coherence ; dynamic data citation ; intelligent semantic agents ; data curation ; snow cover ; big data ; Analysis Ready Data ; climate change ; topology based map algebra ; data provenance ; Sentinel-1 ; Sentinel-2 ; remote sensing ; interoperability ; image data cube ; optical remote sensing ; dual-polarimetric decomposition ; GIS ; Gran Paradiso National Park ; data sharing ; SAR ; map algebra ; Earth observation ; Armenian DC ; data cubes ; Data Cube ; data discovery ; Earth observation data ; persistent identifier ; Landsat ; GRASS GIS ; subset ; landsat ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 81
    Publikationsdatum: 2024-04-05
    Beschreibung: The advent of next-generation sequencing technologies has resulted in a remarkable increase our understanding of human and animal neurological disorders through the identification of disease causing or protective sequence variants. However, in many cases, robust disease models are required to understand how changes at the DNA, RNA or protein level affect neuronal and synaptic function, or key signalling pathways. In turn, these models may enable understanding of key disease processes and the identification of new targets for the medicines of the future. This e-book contains original research papers and reviews that highlight either the impact of next-generation sequencing in the understanding of neurological disorders, or utilise molecular, cellular, and whole-organism models to validate disease-causing or protective sequence variants.
    Schlagwort(e): RC321-571 ; Q1-390 ; Stem Cells ; glycine receptor ; Amyotrophic Lateral Sclerosis ; Parkinson's disease ; PET imaging ; LRRK2 ; Zebrafish ; Inflammation ; GABA-A receptor ; NMDA receptors ; Intellectual Disability ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
    Format: image/jpeg
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  • 82
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Biotic and abiotic stress factors deliver a huge impact on plant life. Biotic stress factors such as damage through pathogens or herbivore attack, as well as abiotic stress factors like variation in temperature, rainfall and salinity, have placed the plant kingdom under constant challenges for survival. As a consequence, global agricultural and horticultural productivity has been disturbed to a large extent. Being sessile in nature, plants cannot escape from the stress, and instead adapt changes within their system to overcome the adverse conditions. These changes include physiological, developmental and biochemical alterations within the plant body which influences the genome, proteome and metabolome profiles of the plant. Since proteins are the ultimate players of cellular behavior, proteome level alterations during and recovery period of stress provide direct implications of plant responses towards stress factors. With current advancement of modern high-throughput technologies, much research has been carried out in this field. This e-book highlights the research and review articles that cover proteome level changes during the course or recovery period of various stress factors in plant life. Overall, the chapters in this e-book has provided a wealth of information on how plants deal with stress from a proteomics perspective.
    Schlagwort(e): QK1-989 ; Q1-390 ; Infection ; signaling events during stress ; Quantitative Proteomics ; heavy metal stress ; plant proteomics ; drought ; high temperature ; Salinity ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Sprache: Englisch
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  • 83
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    Frontiers Media SA
    Publikationsdatum: 2023-12-20
    Beschreibung: Humans are not unique in using tools. But human tool use differs from that known to occur in nonhumans in being very frequent, spontaneous, and diversified. So a fundamental issue is, what are the cognitive and neural bases of human tool use? This Research Topic of Frontiers provides a venue for leading researchers in the field of tool use to present original research papers, integrative reviews or theoretical articles that further our understanding of this topic. Articles address a wide range of issues including, for instance, the nature of the underlying representations (e.g., conceptual, sensorimotor), the mechanisms supporting the incorporation of tools into body schema, the link between imitation and tool use, or the evolutionary origins of human tool use. Articles are included from experimental psychology, neuropsychology, neuroimaging, neurophysiology, developmental psychology, ethology, comparative psychology, and ergonomics. The goal of this Research Topic of Frontiers is to provide a state-of-the-art view of the field.
    Schlagwort(e): BF1-990 ; Q1-390 ; Neural Bases ; tool use ; action ; cognitive bases ; motor control ; bic Book Industry Communication::J Society & social sciences::JM Psychology
    Sprache: Englisch
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  • 84
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: This special issue reviews state-of-the-art approaches to the biophysical roots of cognition. These approaches appeal to the notion that cognitive capacities serve to optimize responses to changing external conditions. Crucially, this optimisation rests on the ability to predict changes in the environment, thus allowing organisms to respond pre-emptively to changes before their onset. The biophysical mechanisms that underwrite these cognitive capacities remain largely unknown; although a number of hypotheses has been advanced in systems neuroscience, biophysics and other disciplines. These hypotheses converge on the intersection of thermodynamic and information-theoretic formulations of self-organization in the brain. The latter perspective emerged when Shannon’s theory of message transmission in communication systems was used to characterise message passing between neurons. In its subsequent incarnations, the information theory approach has been integrated into computational neuroscience and the Bayesian brain framework. The thermodynamic formulation rests on a view of the brain as an aggregation of stochastic microprocessors (neurons), with subsequent appeal to the constructs of statistical mechanics and thermodynamics. In particular, the use of ensemble dynamics to elucidate the relationship between micro-scale parameters and those of the macro-scale aggregation (the brain). In general, the thermodynamic approach treats the brain as a dissipative system and seeks to represent the development and functioning of cognitive mechanisms as collective capacities that emerge in the course of self-organization. Its explicanda include energy efficiency; enabling progressively more complex cognitive operations such as long-term prediction and anticipatory planning. A cardinal example of the Bayesian brain approach is the free energy principle that explains self-organizing dynamics in the brain in terms of its predictive capabilities – and selective sampling of sensory inputs that optimise variational free energy as a proxy for Bayesian model evidence. An example of thermodynamically grounded proposals, in this issue, associates self-organization with phase transitions in neuronal state-spaces; resulting in the formation of bounded neuronal assemblies (neuronal packets). This special issue seeks a discourse between thermodynamic and informational formulations of the self-organising and self-evidencing brain. For example, could minimization of thermodynamic free energy during the formation of neuronal packets underlie minimization of variational free energy?
    Schlagwort(e): RC321-571 ; Q1-390 ; consciousness ; understanding ; Markov blanket ; Hebbian assembly ; neuronal packet ; Bayesian brain ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 85
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    Publications scientifiques du Muséum
    Publikationsdatum: 2023-12-20
    Beschreibung: De nombreux organismes sont composés de parties répétées, identiques ou modifiées (segments de vers de terre, vertèbres, etc.). Ce mode d’organisation fait l’objet depuis la fin du XVIIIe siècle, de nombreuses interrogations de la part des biologistes : quelle est sa signification anatomique, comment se met-il en place lors de l’embryogenèse, que peut-on en déduire sur l’évolution des espèces, etc. ? Ce livre retrace l’histoire de ces questionnements, des théories et des concepts qu’ils ont suscités depuis deux siècles. Il montre que ce problème de la répétition des parties n’a cessé d’occuper une position centrale, au carrefour de plusieurs disciplines biologiques, et ce jusqu’à nos jours.
    Schlagwort(e): Q1-390 ; morphologie transformiste ; vertébré ; phylogenèse ; Naturphilosophie ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Französisch
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  • 86
    Publikationsdatum: 2024-04-05
    Beschreibung: Igneous oceanic crust is one of the largest potential habitats for life on earth, and microbial activity supported by rock-water-microbe reactions in this environment can impact global biogeochemical cycles. However, our understanding of the microbiology of this system, especially the subsurface “deep biosphere” component of it, has traditionally been limited by sample availability and quality. Over the past decade, several major international programs (such as the Center for Dark Energy Biosphere Investigations, the current International Ocean Discovery Program and its predecessor Integrated Ocean Drilling Program, and the Deep Carbon Observatory) have focused on advancing our understanding of life in this cryptic, yet globally relevant, biosphere. Additionally, many field and laboratory research programs are examining hydrothermal vent systems –a seafloor expression of seawater that has been thermally and chemically altered in subseafloor crust – and the microbial communities supported by these mineral-rich fluids. The Frontiers in Microbiology 3 September 2017 | Recent Advances in Geomicrobiology of the Ocean Crust papers in this special issue bring together recent discoveries of microbial presence, diversity and activity in these dynamic ocean environments. Cumulatively, the articles in this special issue serve as a tribute to the late Dr. Katrina J. Edwards, who was a pioneer and profound champion of studying microbes that “rust the crust”. This special issue volume serves as a foundation for the continued exploration of the subsurface ocean crust deep biosphere.
    Schlagwort(e): QR1-502 ; Q1-390 ; IODP ; deep biosphere ; hydrothermal vents ; Geomicrobiology ; ocean crust ; iron oxidation ; sulfate reduction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Sprache: Englisch
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  • 87
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-08-08
    Beschreibung: The Special Issue aimed to bring together scientists working in various branches of control theory to discuss manufacturing control problems that include the following: enterprise control and digital ecosystem creation; the development of identification theory and methodology, and related mathematical problems; parameter, nonparametric, and structure identification and expert analysis; problems regarding selection and data analysis; control systems with an identifier; modeling in intelligent systems; simulation procedures and software; digital identification; reinforcement learning; quantum modeling; intelligent model predictive control; predictive cognitive issues; problems with software quality for complex systems; and global network resources for support processes of modeling and control.
    Schlagwort(e): decision-making ; psychic and behavioral components of activity ; action ; result of activity ; equilibrium stability ; consensus ; threshold behavior ; cognitive dissonance ; conformity ; informational control ; informational confrontation ; soft sensing ; multivariate filter ; reactive distillation ; optimal stochastic control ; path planning ; 2D random search ; interception ; external disturbances ; invariance ; block control principle ; decomposition ; high-gain factors ; sliding mode control ; sigmoid function ; Gramian method ; bilinear system process identification ; generalized Lyapunov equation ; knowledgebase ; associative search models ; wavelet analysis ; adaptive differential evolution ; evolutionary computing ; Hammerstein ; nonlinear system identification ; bilinear systems ; eigenmode decomposition ; spectral expansions ; Gramians ; observability ; controllability ; small-signal analysis ; numerical algorithm ; tokamak ; plasma equilibrium reconstruction ; linear plasma models ; identification ; state observer ; LMI ; least square technique ; deep neural network ; parametric uncertainty ; robust control ; super-stability ; regular form ; dynamic mode decomposition ; system identification ; Runge–Kutta method ; nonparametric model ; artificial neural network ; Izhikevich artificial neuron ; vestibular–ocular reflex ; control Lyapunov function ; Bayes criterion ; Haar wavelets ; loss function ; mean risk ; observable stochastic systems (OStS) ; stochastic process (StP) ; wavelet canonical expansion (WLCE) ; nonparametric identification ; dynamic system ; integral model ; Volterra equations ; smoothing cubic splines ; selection of the smoothing option ; modeling ; regularization ; inverse problems ; balanced identification ; error analysis ; one-dimensional heat equation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
    Sprache: Englisch
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  • 88
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    Presses universitaires de la Méditerranée
    Publikationsdatum: 2022-07-01
    Beschreibung: Les revues de sciences de l’éducation sont un support privilégié pour ce champ. Nous les abordons sous l’angle des mutations et des permanences mais aussi dans la perspective de les lire et d’y publier. Ne nous intéresser qu’aux revues animées par la volonté de « faire science » permet de les distinguer de celles qui expriment des préoccupations strictement professionnelles. Notre sous-titre précise les finalités de l’ouvrage, lire, publier, diffuser, qui ne peuvent être poursuivies que si elles s’appuient sur des écrits sélectionnés, améliorés et validés selon des critères scientifiques et si la diffusion permet d’y accéder. Or, les revues se trouvent confrontées à bien des transformations : la révolution du numérique qui entraîne une réflexion sur les supports, les contraintes économiques de plus en plus pressantes et stressantes, enfin l’omniprésence de l’évaluation. Quels choix effectuer ? Comment les argumenter et les assumer ? Comment informer sur les procédures de décision et de fabrication ? Comment maintenir un haut niveau d’exigence ? Comment aider les « jeunes chercheurs » à être publiés sans y renoncer ? Telles sont les questions dont ce livre s’empare avec le désir explicite de contribuer à l’édification d’un « collège des revues ».
    Schlagwort(e): expertise ; écrire ; diffuser ; doctorant ; publier ; revue ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNT Media, information & communication industries::KNTP Publishing industry & book trade
    Sprache: Französisch
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    Standort Signatur Erwartet Verfügbarkeit
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  • 89
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The range of human neurodegenerative diseases continues to pose significant unmet medical needs for societies around the world. The progressive and terminal nature of these conditions places a considerable personal burden on the individual affected but also on public health systems and health services. Tens of millions of people are indiscriminately affected by various dementias, which are rising at an alarming rate. There are no cures for many conditions, and it is clear that treatments applied as early as possible could greatly improve outcomes for patients. Therefore, new disease classification and diagnostic tools should be a key priority. Metabolomics represents a relatively new field of analytical science, which can be extremely useful in the early diagnosis of disease. The relatively unique feature of metabolites is that they sit at the intersection between the genetic background of an organism and its environment. Because many neurodegenerative diseases are not genetically inherited (instead having a range of known genetic risk factors and also a large number of unknown environmental triggers) the field of metabolomics offers great promise for the discovery of new, biologically, and clinically relevant biomarkers for neurodegenerative disorders. It is already bringing forward new knowledge in terms of the mechanisms of neurodegenerative disease.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; glutamic acid ; n/a ; direct mass spectrometry ; neurodegeneration ; 6-OHDA ; targeted mass spectrometry ; mitochondrial dysfunction ; myo-inositol ; metabolomics ; bile acids ; subacute mild traumatic brain injury ; age-related macular degeneration ; metabolic pathways ; energy metabolism ; midbrain ; Alzheimer’s disease ; biomarkers ; 1H NMR ; Parkinson’s disease dementia ; GC-MS ; pathogenesis ; tricarboxylic acid cycle ; micro-dialysis ; 13C-labeled succinate ; metabolism ; lipidomics ; dementia with Lewy bodies ; fatty acid ; prodromal Parkinson’s disease ; malonate ; cerebral ischemia ; mass spectrometry ; retinal pigment epithelium ; excitotoxicity ; endothelin-1 ; reperfusion ; C. elegans ; Streptomyces venezuelae ; ?-synuclein aggregates ; natural product ; fatty acid metabolism ; imaging mass spectrometry ; LC-MS ; drusen ; cerebral palsy ; plasma ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 90
    Publikationsdatum: 2023-12-20
    Beschreibung: L'origine des pharmacopées traditionnelles L'élaboration des pharmacopées Les médicaments du XXIe siècle Comment les connaissances des savoirs thérapeutiques se sont-elles transmises au travers des différentes cultures ? Cet ouvrage innovant, qui réunit les travaux présentés au 4e Congrès européen d'ethnopharmacologie, fait remonter à la préhistoire les sources des connaissances thérapeutiques. Si les pharmacopées écrites jalonnent l'histoire des grandes médecines savantes, d'autres modes d'accès à la connaissance semblent exister dans l'univers chamanique des sociétés de tradition orale ainsi que dans la façon dont les animaux malades se soignent par les plantes. L'évaluation des propriétés pharmaco-toxicologiques et chimiques des plantes d'usage traditionnel devrait par ailleurs favoriser le développement futur des médicaments à base de plantes, l'un des thèmes porteurs abordés dans cet ouvrage. Mais l'objectif de ce livre est aussi de susciter, partout dans le monde, de nouvelles thématiques de recherche dans le domaine de la préhistoire du médicament et de la compréhension de l'acquisition et de la transmission du savoir. Le développement du phytomédicament non toxique destiné à l'homme et à l'animal figure également parmi les enjeux majeurs de demain.
    Schlagwort(e): H1-99 ; Q1-390 ; paludisme ; guérisseur ; médicament ; ethnobotanique ; médecine traditionnelle ; plante médicinale ; leishmaniose ; ethnopharmacologie ; pharmacopée ; bic Book Industry Communication::H Humanities
    Sprache: Französisch
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    Standort Signatur Erwartet Verfügbarkeit
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  • 91
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.
    Schlagwort(e): QH301-705.5 ; SF1-1100 ; Q1-390 ; n/a ; muscle texture ; fractal analysis ; fish welfare ; Danio rerio ; motivation ; histopathology ; elevated phosphate concentrations ; sharks ; welfare ; African catfish (Clarias gariepinus) ; feed efficiency ; fighting ability ; aggressive interaction ; social rank ; boldness ; ethology ; fisheries management ; physiological response ; FishEthoBase ; welfare scores ; welfare criteria ; stress ; pain ; stereotypical behaviour ; Scyliorhinus canicula ; animal behavior ; welfare enhancement ; social communication ; nociception ; negative and positive affect ; aggression ; fertilisation success ; risk analysis ; aquaculture ; hematology ; Amyloodinium ocellatum ; framework ; structural complexity ; territorial ; growth ; positive welfare ; social stress ; age ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 92
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The re-use of industrial food residues is essential in the general framework of rational waste handling and recycling, which aims at the minimizing environmental impact of food production and producing functional food ingredients. Agri-food processing waste has long been considered a valuable biomass with a significant polyphenol load and profile. Polyphenols, aside from being powerful antioxidants that confer inherent stability to a variety of foods, may possess versatile bioactivities including anti-inflammatory and chemopreventive properties. The valorization of agri-food waste as a prominent source of polyphenols stems from the enormous amount of food-related material discharged worldwide and the emerging eco-friendly technologies that allow high recovery, recycling, and sustainable use of these materials. This book addresses the concept of recovering natural polyphenolic antioxidants from waste biomass generated by agri-food and related industrial processes and presents state-of-the-art applications with prospect in the food, cosmetic, and pharmaceutical industries.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; valorization ; ultrasound assisted extraction ; microwave assisted extraction ; Box–Behnken design ; HPLC-DAD-q-TOF-MS ; Dioscorea batatas ; green oleo-extraction ; grape marc ; quantitative analysis ; natural antioxidants and flavors ; antioxidant ; infrared-assisted extraction ; anti-ageing ; anthocyanins ; liquid chromatography-mass spectrometry ; Chinese yam ; functional food ; extraction ; olive mill wastewater ; adsorbents ; relative solubility simulation ; HPLC-fluorometric detector (FLD)–MS ; saffron ; antioxidants ; food-grade solvents ; Mango ; zero-waste biorefinery ; response surface methodology ; ophthalmic hydrogel ; olive leaves ; sonotrode ultrasonic-assisted extraction ; vegetable oils and derivatives ; anti-inflammatory ; skin whitening ; phenolics ; Brewers’ spent grains ; proanthocyanidins ; brewer’s spent grain ; anti-inflammatory and antioxidant activity ; antimicrobial activity ; by-products ; antiplatelet activity ; phenanthrenes ; wine lees ; bioactive compounds ; deep eutectic solvents ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 93
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-02-01
    Beschreibung: Radiopharmaceuticals are used in the diagnosis and treatment of various diseases, especially cancer. In general, radiopharmaceuticals are either salts of radionuclides or radionuclides bound to biologically active molecules, drugs, or cells. Tremendous progress has been made in discovering, developing, and commercializing numerous radiopharmaceuticals for the imaging and therapy of cancer. Significant research is ongoing in academia and the pharmaceutical industry to develop more novel radiolabeled compounds as potential radiopharmaceuticals for unmet needs. This Special Issue aims to focus on all aspects of the design, characterization, evaluation, and development of novel radiolabeled compounds for the diagnosis and treatment of cancer and the application of new radiochemistry and methodologies for the development of novel radiolabeled compounds. Outstanding contributions presented in this Special Issue will significantly add to the field of radiopharmaceuticals.
    Schlagwort(e): positron emission tomography (PET) ; pyrazoles ; fluorine-18 ; radionuclides ; PET probes ; imaging pharmaceuticals ; hypopharyngeal cancer ; 188Re-liposome ; repeated therapy ; NGS ; microRNA ; aprepitant ; radiopharmaceuticals ; neurokinin 1 receptor antagonist ; radionuclide chelators ; kidney uptake ; cleavable linkers ; neutral endopeptidase (NEP) ; renal brush border enzymes ; prostate-specific membrane antigen (PSMA) ; cancer imaging and therapy ; somatostatin analogs ; radiolabeling ; radionuclide therapy ; imaging ; adrenergic receptor ; positron emission tomography ; radiotracer ; cholecystokinin-2 receptor ; minigastrin ; molecular imaging ; targeted radiotherapy ; lutetium-177 ; EpCAM ; radionuclide ; SPECT ; iodine ; PIB ; breast ; cancer ; PET ; target-specific biomolecules ; immunoPET imaging pharmaceuticals ; production processes ; 124I-labeled monoclonal antibodies ; radiotracers ; AAZTA ; scandium-44 ; FAP ; SA ; DPP ; PREP ; radioiodine labeling ; radioiodination ; biomolecules ; peptides ; proteins ; monoclonal antibodies ; 123,124,125,131I-labeled molecules and biomolecules ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
    Sprache: Englisch
    Format: image/jpeg
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  • 94
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    Collège de France
    Publikationsdatum: 2023-12-20
    Beschreibung: Comment expliquer le paradoxe fondamental de la matière vivante, qui allie stabilité et robustesse des formes à une dynamique interne constante ? Ce n’est pas seulement l’information génétique contenue dans les cellules, mais aussi les processus biochimiques et moléculaires observables in vivo qui sont à l’œuvre dans la morphogenèse. S’y ajoute la contribution essentielle des forces mécaniques qui, de la molécule au tissu, modèlent l’organisme. La dynamique du vivant émerge ainsi du contrôle biologique et des contraintes physiques à toutes les échelles. Son étude réunit aujourd’hui une communauté interdisciplinaire en pleine expansion qui observe, analyse et modélise le vivant.
    Schlagwort(e): Q1-390 ; plasticité tissulaire ; morphogenèse ; biologie ; sciences du vivant ; architecture tissulaire ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Französisch
    Format: image/png
    Standort Signatur Erwartet Verfügbarkeit
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  • 95
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-02-20
    Beschreibung: A collection of 18 scientific papers written in honor of Professor Karlheinz Schwarz's 80th birthday. The main topics include spectroscopy, excited states, DFT developments, results analysis, solid states, and surfaces.
    Schlagwort(e): density functional theory ; Coulomb systems ; excited states ; nodal variational principle ; DFT ; anatase TiO2(101) surface ; adsorption energy ; Bader charge ; helium atom ; screened Coulomb potential ; variational Monte Carlo method ; Lagrange mesh method ; comparison theorem ; TD-DFT ; MC-PDFT ; Lie–Clementi ; Colle–Salvetti ; OLEDs ; subphthalocyanines ; UV–visible spectra ; axial substituents ; peripheral substituents ; time-dependent DFT ; hexatetra-carbon ; electrical properties ; molecular aggregates ; singlet excitons ; triplet excitons ; TDDFT ; charge-transfer states ; charge-resonance states ; Frenkel states ; localized excitations ; diabatic states ; adiabatic states ; semiconductors ; oscillator strength ; hybrid exchange-correlation functional ; non-local potential ; statistics ; methods comparison ; benchmarking ; band gaps ; atomization energy ; DFT codes ; electronic structure calculation ; numerical accuracy and precision ; kinetic functional ; Yukawa potential ; periodic DFTB ; deMonNano ; graphene ; graphite ; benzene dimers ; deposited benzene ; supported clusters ; weighted mulliken charges ; LAPW method ; APW+lo method ; all-electron DFT ; density matrix functional embedding ; density-functional theory ; householder transformation ; He atomic basis sets ; helium dimer ; He2 potential well ; correlation energy ; complete basis set ; sigma basis set ; atomic multiplet theory ; crystal/ligand-field theory ; coordination compounds ; electronic structure ; Cu2OCl2 ; Cu2OBr2 ; Cu2OI2 ; oxyhalides ; magnetic couplings ; Néel temperature ; chemical pressure ; NMR ; machine learning ; zeolites ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNR Physical chemistry
    Sprache: Englisch
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  • 96
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    Éditions de la Maison des sciences de l’homme
    Publikationsdatum: 2023-12-20
    Beschreibung: Les singes s'épouillent, les araignées tissent, les lionnes chassent, les oiseaux chantent et les castors bâtissent. Les activités des animaux ont toujours beaucoup intéressé les biologistes et les psychologues. Mais l'étude des interactions de l'animal avec son milieu ne peut pas s'arrêter là : il faut aussi prendre en compte la perception que cet animal se fait des situations rencontrées ainsi que les émotions qu'il éprouve à leur sujet. Force est de constater que l'étude des comportements a souvent été privilégiée, au détriment d'aspects fonctionnels, qui sont, certes, plus difficiles à objectiver. L'étude de ces questions est essentielle pour mieux comprendre l'animal. Cet ouvrage, très fourni en exemples, très détaillé et très précis, nous offre la possibilité de faire le point sur le champ de l'éthologie cognitive, mais aussi et surtout sur son étendue et sur ses influences.
    Schlagwort(e): Q1-390 ; cognition ; éthologie ; psychologie ; comportement ; animaux ; moeurs ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Französisch
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    Standort Signatur Erwartet Verfügbarkeit
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  • 97
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-12-06
    Beschreibung: This Special Issue collects original research articles discussing cutting-edge work as well as perspectives on future directions in the whole range of theoretical and practical aspects in these research areas: i) Theory of fuzzy systems and soft computing; ii) Learning procedures; iii) Decision-making applications employing fuzzy logic and soft computing.
    Schlagwort(e): fuzzy partition ; fuzzy transform ; new iterative method ; Cauchy problems ; ANFIS ; basmati rice ; image processing ; grading ; quality assessment ; fuzzy inference system ; causality ; statistics ; concept-mapping ; causal graph ; numerical methods ; systems of ordinary differential equations ; NIM ; fuzzy logics ; linear motion blur ; fuzzy deblurring ; electron beam calibration ; signal and image processing ; propagation modeling ; adaptive-network-based fuzzy system ; LoRa &amp ; LoRaWAN ; radio wave propagation ; artificial neural networks ; subtracting clustering ; dual double fuzzy semi-metric ; double fuzzy semi-metric ; fuzzy semi-metric space ; triangle inequality ; triangular norm ; eye gaze tracking ; interval type-2 fuzzy logic ; vision system ; mobile robots ; intelligent control ; ordered fuzzy number ; fuzzy relation ; preorder ; strict order ; equivalence relation ; variable neighborhood search ; experimental comparison ; statistical analysis ; traveling salesman problem ; soft computing ; modeling ; vector optimization ; methods of solution of vector problems ; optimal decision-making ; numerical realization of decision-making ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
    Sprache: Englisch
    Format: image/jpeg
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  • 98
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-12-20
    Beschreibung: Ice crystals are the most ubiquitous material found in the cryosphere environment of the Earth, in the planetary system, and also in our daily lives. In recent years, ice crystals have increased in importance as one of the key materials for finding solutions to settle various environmental concerns at a global scale. Furthermore, ice crystals are unique materials which are potentially extremely useful in various applications, for example, within the food sciences, medical sciences, and other fields. In dealing with these interesting subjects, research on ice crystals has been more actively pursued in recent years. The Special Issue “Ice Crystals” presents a wide varieties of topics related to ice crystals. It can be considered as a status report reviewing the recent research on ice crystals and serves to provide readers with information on the latest developments concerning ice crystals.
    Schlagwort(e): Q1-390 ; QC1-999 ; coarsening kinetics ; antifreeze protein ; microstructure ; ice crystals ; decomposition ; formation ; cryo-photo microscopy ; cryoprotective agent ; ice cream ; reformation ; tomography ; deformation ; clathrate hydrate ; Negative thermal expansivity ; tetrahydrofuran ; ice crystal ; pressure ; molecular dynamics ; Grüneisen parameter ; modelling ; ab initio calculation ; freezing ; nanoscale pores ; quasi-liquid layer ; electron paramagnetic resonance ; potential of mean force ; gas hydrate ; spin labeling ; pre-decomposition pressure ; mW model ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 99
    Publikationsdatum: 2024-04-05
    Beschreibung: Electrocochleography (ECochG) is an approach for objective measurements of physiologic responses from the inner ear. Measurements have classically been made from electrodes placed in the outer ear canal, on the tympanic membrane, the round window niche, or inside the cochlea. Recent innovations have led to ECochG being used for exciting new purposes that drive clinical practice and contribute to the basic understanding of inner ear physiology. Cochlear implant recording electrodes can monitor the preservation of residual, low-frequency acoustic hearing, both in the operating room and post-operatively. ECochG measurements can quantify differential effects of inner ear surgery or other manipulations on vestibular and auditory physiology simultaneously. Various attributes of cognitive neuroscience can be addressed with ECochG measurements from the auditory periphery. These advances in ECochG provide a way to understand a variety of inner ear diseases and are likely to be of value to many groups in their own clinical and basic research.
    Schlagwort(e): RC321-571 ; Q1-390 ; cochlear microphonic ; cochlear action potential ; sensorineural hearing loss ; compound action potential ; auditory nerve ; medial olivocochlear efferent reflex ; electrocochleography ; summating potential ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 100
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-05-06
    Beschreibung: Thanks to their rich chemodiversity, marine natural products represent a unique source of new bioactive metabolites. As the new leading compounds in drug discovery and development, these molecules may represent challenges for the treatment of a number of human diseases, attracting the attention of many researchers during their chemical and biological studies. This Special Issue covers all fields of drugs research in which marine natural products are involved, including their isolation and characterization, biological activities, and medicinal applications as well as synthetic approaches and their related analogues. The cover picture shows “The Nudibranch mollusk Godiva quadricolor on a sponge, reflected under the surface during the low tide. Fusaro Lagoon, Bacoli (Naples)”.
    Schlagwort(e): alginate ; Sargassum duplicatum ; okra ; antioxidant ; diabetic ; wound healing ; sulfavant ; sulfoquinovosyldiacylglycerols ; sulfoglycolipids ; mass spectrometry ; UHPLC-MS ; lipids ; cancer therapy ; gold nanoparticles ; marine products ; natural products ; photosensitizer ; purpurin 18 ; reactive oxygen species ; seaweed ; biosilica ; diatom frustule ; sustainable production ; drug delivery ; Sargassum ilicifolium ; mangosteen rind ; diabetic mice ; Aquimarina sp. ; diketopiperazine ; N-phenethylacetamide ; epithelial-mesenchymal transition (EMT) ; A549 cells ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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