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  • Artikel  (1.385)
  • Biochemistry and Biotechnology  (885)
  • Humans  (500)
  • 1975-1979  (1.385)
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  • Artikel  (1.385)
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  • 1
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    Treatment reduces deaths from hypertension (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-21
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1386-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505012" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Antihypertensive Agents/therapeutic use ; Blood Pressure ; Diet, Sodium-Restricted ; Female ; Humans ; Hypertension/complications/*drug therapy/physiopathology ; Male ; Myocardial Infarction/etiology/prevention & control
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
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    Perception of size of one object among many (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-21
    Beschreibung: Adaptation to a grating of properly chosen frequency may lead to two apparently conflicting observations: Another grating may then appear to be of increased frequency (compared with its "unadapted" frequency) while the individual bars of the grating appear to have widened. This perceived widening parallels previous results with single bars. By attending to only one grating bar, the subject effectively seems to change the grating frequency spectrum to that of a single bar.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Levinson, J Z -- Frome, F S -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1425-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505017" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adaptation, Physiological ; Humans ; Size Perception/*physiology ; Visual Fields ; Visual Perception/*physiology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
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    Cancer and industrial chemical production (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-21
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Davis, D L -- Magee, B H -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1356, 1358.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505010" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Environmental Exposure ; Humans ; *Industry ; Neoplasms/*chemically induced/epidemiology ; United States
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 4
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    Legionnaires' disease: concentrations of selenium and other elements (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-21
    Beschreibung: Selenium concentrations in the serums of 17 acutely ill Legionnaires' disease patients were significantly lower than in their matching convalescent-phase serums. This trend was not observed in ten similarly paired samples of serum from control patients with pneumonia. There were no significant differences in the concentrations of nickel, copper, bromine, rubidium, lead, barium, or titanium in the serums of Legionnaires' disease and control patients.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chen, J R -- Anderson, J M -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1426-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505018" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Humans ; Legionnaires' Disease/*blood ; Metals/blood ; Nickel/blood ; Selenium/*blood
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 5
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    Fetal mortality and sex ratio (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-21
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lowry, J T -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1428.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505019" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Female ; Fetal Death/*epidemiology ; Humans ; Male ; Pregnancy ; *Sex Ratio
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
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    Metabolism of theophylline to caffeine in human fetal liver (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-14
    Beschreibung: Caffeine (1,3,7-trimethylxanthine) is a biotransformation product of theophylline (1,3-dimethylxanthine) in the human fetus. Liver explants, obtained from human fetuses with gestational ages of 12 to 20 weeks, were incubated with theophylline and produced caffeine and, in lesser amounts, 1,3-dimethyluric acid and 3-methylxanthine. These findings suggest that the predominant pathway in theophylline metabolism in the fetus and newborn infant is the methylation reaction producing caffeine. This may contribute to the neonate's exceedingly slower elimination of caffeine relative to theophylline. Caffeine produced from theophylline may add to the pharmacologic effects of theophylline in newborn infants with apnea.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Aranda, J V -- Louridas, A T -- Vitullo, B B -- Thom, P -- Aldridge, A -- Haber, R -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1319-21.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/515734" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Apnea/drug therapy ; Biotransformation ; Caffeine/*biosynthesis/metabolism/therapeutic use ; Cells, Cultured ; Gestational Age ; Humans ; Infant, Newborn ; Liver/*embryology/metabolism ; Methylation ; Theophylline/*metabolism/therapeutic use
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
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    Food additives (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-14
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Benarde, M A -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1256-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/515730" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): *Carcinogens ; Food Additives/*adverse effects ; Humans ; Public Opinion
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 8
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    Shifts in perception of size after adaptation to gratings (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-14
    Beschreibung: After viewing a suitable grating of vertical stripes for 5 minutes, subjects overestimated the width of a rectangle by 6 percent. The shifts in perception of size occurred whether individual stripes in the grating were narrower than, equal to, or wider than the rectangle. Rectangle width was underestimated only if the grating stripes were extremely wide, with a spatial frequency lower than most of the effective amplitude spectrum of the rectangle. These findings (and complementary ones with horizontal gratings) suggest that the visual system codes size on the basis of spatial frequency components, rather than directly in terms of width.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Frome, F S -- Levinson, J Z -- Danielson, J T -- Clavadetscher, J E -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1327-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/515736" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): *Adaptation, Physiological ; Humans ; Size Perception/*physiology ; Visual Fields ; Visual Perception/*physiology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 9
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    Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-14
    Beschreibung: Current concepts of the pathogenesis of emphysema suggest that it results from an imbalance of elastase and antielastase activity within the alveolar structures. Although emphysema that is associated with hereditary deficiency of serum alpha 1-antitrypsin conforms to this scheme, the major risk factor in the more common form of emphysema is cigarette smoking. A study was designed to evaluate the premise that cigarette smoking may be associated with an acquired, functional defect in lung alpha 1-antitrypsin. Determination of the antielastase activity of alpha 1-antitrypsin obtained from the lungs of smoking and nonsmoking individuals revealed a nearly twofold reduction in the functional activity of this elastase inhibitor in the lungs of cigarette smokers. These data suggest that cigarette smokers may lose some of the normal antielastase protective screen of the lower respiratory tract, making them more vulnerable to destructive lung disease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gadek, J E -- Fells, G A -- Crystal, R G -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1315-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/316188" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adult ; Bronchi/enzymology ; Extracellular Space/enzymology ; Humans ; Lung/*enzymology ; Pancreatic Elastase/antagonists & inhibitors ; Plants, Toxic ; Pulmonary Emphysema/enzymology/etiology ; Smoking/complications/*physiopathology ; Tobacco ; *alpha 1-Antitrypsin Deficiency
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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  • 10
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    Killing of fibroblasts by dexamethasone or dibutyryl adenosine 3',5'-monophosphate is not a valid test for cystic fibrosis (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1979-12-14
    Beschreibung: Assays based on the counting of total cells and of colony-forming cells were used to demonstrate that neither dexamethasone nor dibutyryl adenosine 3',5'-monophosphate (cyclic AMP) kills human fibroblasts under a variety of conditions. These results contradict those of previous studies showing that dexamethasone and dibutyryl cyclic AMP kill a higher percentage of fibroblasts from normal humans than from individuals with cystic fibrosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kurz, J B -- Perkins, J P -- Buchwald, M -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1317-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/229552" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adolescent ; Adult ; Bucladesine/*pharmacology ; Cell Division/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Child ; Child, Preschool ; Cystic Fibrosis/*diagnosis ; Dexamethasone/*pharmacology ; Dose-Response Relationship, Drug ; Female ; Fibroblasts/*drug effects ; Humans ; Ouabain/pharmacology ; Skin/cytology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
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