ALBERT

Keywords: *Advisory Committees ; *Containment of Biohazards ; *DNA, Recombinant ; *Federal Government ; *Government Regulation ; *National Institutes of Health (U.S.) ; United States

Keywords: *Advisory Committees ; *DNA, Recombinant ; Federal Government ; *Government Regulation ; *National Institutes of Health (U.S.) ; *Professional Staff Committees ; United States

Keywords: Animals ; *Jurisprudence ; Malathion/adverse effects ; *National Institutes of Health (U.S.) ; Neoplasms/chemically induced ; United States

Keywords: Acquired Immunodeficiency Syndrome ; *Budgets ; Centers for Disease Control and Prevention (U.S.) ; *Financial Management ; Humans ; *National Institutes of Health (U.S.) ; *Research ; United States ; United States Substance Abuse and Mental Health Services Administration

Keywords: History, 20th Century ; *National Institutes of Health (U.S.) ; United States

Keywords: Bacterial Toxins/*genetics ; *Cloning, Molecular ; Containment of Biohazards ; Escherichia coli/genetics ; *National Institutes of Health (U.S.) ; Shiga Toxins ; United States

Keywords: Costs and Cost Analysis ; *National Institutes of Health (U.S.) ; *Research Support as Topic ; United States ; *Universities

Keywords: Academies and Institutes ; *Embryo Research ; *Embryo, Mammalian ; Federal Government ; *Fertilization in Vitro ; Fetus ; Government ; *Government Regulation ; Humans ; *National Institutes of Health (U.S.) ; *Research ; *Research Personnel ; *Social Control, Formal

Keywords: *Advisory Committees ; Containment of Biohazards ; *DNA, Recombinant ; *Federal Government ; *Government Regulation ; *National Institutes of Health (U.S.) ; United States ; Health has encountered setbacks in its attempt to increase its regulatory ; authority over genetic engineering ventures. Competing claims by the ; Environmental Protection Agency have been supported in a congressional report ; authored by Rep. Albert Gore, Jr. (D-Tenn.) which is critical of RAC's actions in ; approving experimental release of genetically-modified organisms into the ; environment. During a 6 Feb 1984 public meeting, RAC faced a barrage of criticism ; led by activist Jeremy Rifkin, and learned of a U.S. Court of Appeals decision ; blocking its consideration of a proposed field test with engineered bacteria.

Keywords: Costs and Cost Analysis ; *National Institutes of Health (U.S.) ; *Research Support as Topic ; United States

Keywords: Acquired Immunodeficiency Syndrome/*economics ; Humans ; *National Institutes of Health (U.S.) ; Neoplasms/*economics ; Politics ; *Research Support as Topic ; United States

Keywords: History, 20th Century ; Humans ; *National Institutes of Health (U.S.) ; Neoplasms ; Research Support as Topic ; United States

Keywords: *Advisory Committees ; *DNA, Recombinant ; *Federal Government ; *Government Regulation ; *National Institutes of Health (U.S.) ; United States ; Recombinant DNA Advisory Committee (RAC) are seen as potentially detrimental to ; RAC's credibility. Each session was closed on grounds that proprietary data were ; being reviewed. NIH Director James B. Wyngaarden has implemented a formal review ; of the extent of the authority of RAC, which currently reviews not only research ; projects funded by its parent agency but also voluntarily-submitted industrial ; proposals and proposals of other federal government agencies.

Keywords: *Education, Medical, Continuing ; *National Institutes of Health (U.S.) ; *Research ; *Training Support ; United States

Keywords: *National Institutes of Health (U.S.) ; *Neoplasms ; *Professional Staff Committees ; United States

Keywords: Animals ; Mice ; *National Institutes of Health (U.S.) ; Nuclear Transfer Techniques ; *Research Support as Topic ; Switzerland ; United States

Keywords: Humans ; Legislation, Medical ; *National Institutes of Health (U.S.) ; Neoplasms/mortality/*prevention & control ; *Research ; United States

Keywords: *Biomedical Research ; *Crime ; Federal Government ; *Fraud ; *Government Regulation ; *National Institutes of Health (U.S.) ; Research/*standards ; United States ; look into institutional procedures at Emory University, where an internal ; investigation had revealed extensive data fabrication by John Darsee, found a ; pattern of lax supervision of Darsee's research. Rather than prescribe action for ; Emory alone, the panel recommended seven procedural steps that should be taken by ; all NIH-supported research centers to guard against similar occurrences. These ; recommendations are being reviewed by NIH.

Keywords: Advisory Committees ; DNA, Recombinant ; Federal Government ; *Genetic Engineering ; *Government Regulation ; Jurisprudence ; *National Institutes of Health (U.S.) ; United States ; recommended to NIH director James B. Wyngaarden on 1 June 1984 that two ; companies, Cetus Corporation and Advanced Genetic Sciences, Inc., be allowed to ; proceed with experiments involving release into the environment of organisms ; altered by gene splicing. The recommendation followed by two weeks a ruling by ; federal judge John J. Sirica which halted a very similar experiment by ; federally-funded University of California researcher Steven Lindow. The ruling ; did not apply to experiments conducted by private companies. Wyngaarden thus ; faces the political dilemma that, if he accepts the advisory committee's ; recommendation, a dual standard will be established allowing industry to conduct ; experiments that university scientists are currently barred from doing.

Keywords: Federal Government ; *Genetic Engineering ; *Government Regulation ; Judicial Role ; *Jurisprudence ; *National Institutes of Health (U.S.) ; United States ; of genetically engineered bacteria, the National Institutes of Health will ; conduct the simpler of two ecological analyses required by the National ; Environmental Policy Act on three proposed experiments. In May 1984 a federal ; district court ruling halted a University of California field test pending a ; decision on Rifkin's 1983 suit, which alleged that NIH had violated the Act by ; approving experiments without studying the ecological consequences. Still to be ; decided by the U.S. Court of Appeals is whether NIH must also issue full-scale ; environmental impact statements.

Keywords: Animals ; *Genetic Engineering ; Humans ; *National Institutes of Health (U.S.) ; Sheep ; Swine ; United States

Keywords: Advisory Committees ; Containment of Biohazards ; Ethics Committees, Research ; Federal Government ; Genetic Diseases, Inborn ; *Genetic Engineering ; Government Regulation ; Judicial Role ; Jurisprudence ; *National Institutes of Health (U.S.) ; United States ; Administration, the first authorized experiments in human gene therapy are ; expected to begin sometime in 1985. Anticipating approval, the congressional ; Office of Technology Assessment (OTA), at the request of then Representative ; Albert Gore, Jr. (D-Tenn), compiled a report on the scientific and ethical issues ; involved. OTA found no unique ethical obstacles to somatic cell therapy if ; conducted safely and with a reasonable expectation of efficacy. It reached no ; agreement concerning the necessity, feasibility, or ethical acceptability of ; germline therapy, and recommended further evaluation and public discussion.

Keywords: *National Institutes of Health (U.S.) ; *Neoplasms ; *Professional Staff Committees ; United States