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  • Books  (3,241)
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  • Q1-390  (1,698)
  • thema EDItEUR::N History and Archaeology  (1,543)
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  • Books  (3,241)
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  • 1
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    John Miles Foley's World of Oralities (2021)
    Arc Humanities Press
    Details
    Publication Date: 2024-03-27
    Description: This collection brings together newly commissioned and cutting-edge essays on oral text and tradition ranging from the ancient and medieval world to the present day by a leading group of European and North American oral theorists. Using a range of materials including the Bible, Greek epic, Beowulf, Old Norse and Old English riddles, and medieval music, the contributors collectively work to refine, challenge, and further advance contemporary Oral Theory, an interdisciplinary school of thought heavily influenced by John Miles Foley, whose work provides the jumping-off point for this volume. The book includes a useful introduction to the history of oral theory and Foley’s ground-breaking and influential work.
    Keywords: Oral tradition; orality; performance; composition; narrative; Old Norse; Folklore; Beowulf; Medieval Music; Scandinavian religion; Anglo-Saxon Literature ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general::DSBB Literary studies: ancient, classical and medieval ; thema EDItEUR::D Biography, Literature and Literary studies::DB Ancient, classical and medieval texts ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs::QRR Other religions and spiritual beliefs::QRRT Indigenous, ethnic and folk religions and spiritual beliefs::QRRT1 Indigenous religions, spiritual beliefs and mythologies of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTD Oral history ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFF Historical and comparative linguistics ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500 ; thema EDItEUR::N History and Archaeology::NH History::NHC Ancient history
    Language: English
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  • 2
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    Inszenierte Moderne. Populäres Theater in Berlin und London, 1880-1930 (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Description: Modern popular culture came to the world from the stage. Even before film and radio had established themselves, popular theater had developed into a commercial and boundary-crossing entertainment industry that reached a mass audience. Tobias Becker compares the theater landscapes of London and Berlin and points out the cultural exchanges that took place between these metropolises during the long turn of the century (1880&#82111930).
    Keywords: D204-475 ; media history ; German-British history ; theater history ; urban history ; history of popular culture ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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  • 3
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    Provinz zwischen Reich und Republik. Politische Mentalitäten in Deutschland und Frankreich 1918-1933/36 (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Keywords: D204-475 ; DD1-905 ; JA1-92 ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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  • 4
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    Cancer Nanotheranostics: What Have We Learned So Far? (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer. Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action. These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments. Future in vivo work will need to carefully consider the correct choice of chemical modifications to incorporate into the multifunctional nanocarriers to avoid activation off-target, side effects and toxicity. Moreover the majority of studies on nanomaterials do not consider the final application to guide the design of nanomaterial. Instead, the focus is predominantly on engineering materials with specific physical or chemical properties. It is imperative to learn how advances in nanosystem’s capabilities are being used to identify new diagnostic and therapy tools driving the development of personalized medicine in oncology; discover how integrating cancer research and nanotechnology modeling can help patient diagnosis and treatment; recognize how to translate nanotheranostics data into an actionable clinical strategy; discuss with industry leaders how nanotheranostics is evolving and what the impact is on current research efforts; and last but not least, learn what approaches are proving fruitful in turning promising clinical data into treatment realities.
    Keywords: QD1-999 ; Q1-390 ; Nanoparticles ; Gene Therapy ; Immunotherapy ; bioimaging ; theranostics ; nanomaterials ; Drug delivery ; Nanomedicine ; Cancer ; Phototherapy ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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  • 5
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    Normatividades e instituciones eclesiásticas en el virreinato del Perú, siglos XVI–XIX (2021)
    Max Planck Institute for Legal History and Legal Theory
    Details
    Publication Date: 2024-03-23
    Description: Ecclesiastical institutions and actors were essential for the formation of normative orders in early modern Ibero-America. In a series of seminars, organised by the Max Planck Institute for European Legal History in Mexico City, Lima, Bogotá and São Paulo, scholars from different disciplines presented innovative studies on the history of religious normativity and its practices. Based upon the Lima colloquium, the present volume focuses on the viceroyalty of Peru (16th-19th centuries).
    Keywords: Ibero-American history (16th–19th centuries) ; viceroyalty of Peru ; derecho indiano ; canon law ; church history ; ecclesiastical legislation ; litigation in canon law ; religious orders ; diocesan administration ; royal patronage ; evangelization ; thema EDItEUR::1 Place qualifiers::1K The Americas::1KL Latin America – Mexico, Central America, South America::1KLS South America::1KLSR Peru ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::L Law::LA Jurisprudence and general issues::LAZ Legal history
    Language: Spanish
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  • 6
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    Darwin au Collège de France (2021)
    Collège de France
    Details
    Publication Date: 2022-02-01
    Description: La théorie de Darwin aussi bien que sa réception scientifique, littéraire et politique en France continuent d’être matière à débat. Les controverses qu’elle a suscitées à partir de la première traduction française de L’Origine des espèces en 1862 n’ont pas été le seul fait des naturalistes, des géologues ou des paléontologues. De nombreux autres savants se sont préoccupés de l’impact du darwinisme sur leur discipline, notamment en philologie, dans les mathématiques, la linguistique, la psychologie comparée, l’histoire ou la philosophie. Les auteurs des textes réunis dans Darwin au Collège de France montrent que le Collège de France constitue un point de référence idéal pour étudier les idées de Darwin et leur réception ainsi que la manière dont elles ont pu jouer sur la formation des disciplines du milieu du xixe siècle jusqu’à aujourd’hui. Parmi les défenseurs ou les adversaires français du darwinisme, on compte en effet plusieurs de ses professeurs, à commencer par Pierre Flourens, dont l’Examen du livre de M. Darwin (1864) a été l’un des premiers comptes rendus hostiles de L’Origine des espèces. D’autres figurent encore dans la liste : Ernest Renan, Edgar Quinet, Théodule Ribot, Jean-Charles Lévêque, Étienne-Jules Marey, Jean-François Nourrisson, Michel Bréal, Gabriel Tarde, Henri Bergson, Étienne Gilson. À cette liste s’ajoutent les professeurs de biologie, de médecine, de paléontologie, de neurosciences, ou d’économie politique. Le colloque, dont les contributions sur quelques-uns des savants mentionnés ci-dessus sont réunies dans le deuxième volume de la collection « Passage des disciplines », a été organisé par Alain Prochiantz et Antoine Compagnon dans le cadre du projet « Passage des disciplines : Histoire globale du Collège de France, xixe siècle - xxe siècle », qui s’intéresse à l’évolution des matières enseignées aussi bien que celles qui ont n’y ont pas été admises et qui forment un « Collège virtuel », depuis la fin du xviiie siècle jusqu’aux années 1960. Il est dirigé par Antoine Compagnon, avec la collaboration de Céline Surprenant et le soutien financier de PSL (2016-2019), et de la Fondation Hugot.
    Keywords: P ; D1-2009 ; PN1-6790 ; B1-5802 ; H1-99 ; Q1-390 ; literary criticism ; biology ; psychology ; history of sciences ; social sciences ; literary history ; higher education ; life sciences ; history of ideas ; philosophy ; research
    Language: French
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  • 7
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    Cutting-Edge Technologies for Renewable Energy Production and Storage (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2023-12-20
    Description: Anthropogenic greenhouse gas (GHG) emissions are dramatically influencing the environment, and research is strongly committed to proposing alternatives, mainly based on renewable energy sources. Low GHG electricity production from renewables is well established but issues of grid balancing are limiting their application. Energy storage is a key topic for the further deployment of renewable energy production. Besides batteries and other types of electrical storage, electrofuels and bioderived fuels may offer suitable alternatives in some specific scenarios. This Special Issue includes contributions on the energy conversion technologies and use, energy storage, technologies integration, e-fuels, and pilot and large-scale applications.
    Keywords: Q1-390 ; QC1-999 ; n/a ; PV ; GHG savings ; lithium-ion battery (LIB) ; probability prediction ; decarbonization ; supercapacitor (SC) ; least squares support vector machine ; EV fleet forecasts ; alternative maritime power (AMP) ; Markov chain ; feasibility study ; D funding ; hybrid power system ; numerical analysis ; ship structure ; optimal sizing ; cellulosic ethanol ; electric vehicles EV ; biofuel ; green ship ; R&amp ; bulk carrier ; molten carbonate fuel cell system ; sparse Gaussian process regression ; power-to-gas ; combination method ; charging infrastructure ; jet fuel ; flow characteristics ; hybrid refinery ; LNG-fueled ship ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 8
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    Advances in Microalgae Biology and Sustainable Applications (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-11
    Description: It has become more evident that many microalgae respond very differently than land plants to diverse stimuli. Therefore, we cannot reduce microalgae biology to what we have learned from land plants biology. However, we are still at the beginning of a comprehensive understanding of microalgae biology. Microalgae have been posited several times as prime candidates for the development of sustainable energy platforms, making thus the in-depth understanding of their biological features an important objective. Thus, the knowledge related to the basics of microalgae biology must be acquired and shared rapidly, fostering the development of potential applications. Microalgae biology has been studied for more than forty years now and more intensely since the 1970’s, when genetics and molecular biology approaches were integrated into the research programs. Recently, studies on the molecular physiology of microalgae have provided evidences on the particularities of these organisms, mainly in model species, such as Chlamydomonas reinhardtii. Of note, cellular responses in microalgae produce very interesting phenotypes, such as high lipid content in nitrogen deprived cells, increased protein content in cells under high CO2 concentrations, the modification of flagella structure and motility in basal body mutant strains, the different ancient proteins that microalgae uses to dissipate the harmful excess of light energy, the hydrogen production in cells under sulfur deprivation, to mention just a few. Moreover, several research groups are using high-throughput and data-driven technologies, including “omics” approaches to investigate microalgae cellular responses at a system-wide level, revealing new features of microalgae biology, highlighting differences between microalgae and land plants. It has been amazing to observe the efforts towards the development and optimization of new technologies required for the proper study of microalgae, including methods that opened new paths to the investigation of important processes such as regulatory mechanisms, signaling crosstalk, chemotactic mechanisms, light responses, chloroplast controlled mechanisms, among others. This is an exciting moment in microalgae research when novel data are been produced and applied by research groups from different areas, such as bioprocesses and biotechnology. Moreover, there has been an increased amount of research groups focused in the study of microalgae as a sustainable source for bioremediation, synthesis of bioproducts and development of bioenergy. Innovative strategies are combining the knowledge of basic sciences on microalgae into their applied processes, resulting in the progression of many applications that hopefully, will achieve the necessary degree of optimization for economically feasible large-scale applications. Advances on the areas of basic microalgae biology and novelties on the essential cellular processes were revealed. Progress in the applied science showed the use of the basic science knowledge into fostering translational research, proposing novel strategies for a sustainable world scenario. In this present e-book, articles presented by research groups from different scientific areas showed, successfully, the increased development of the microalgae research. Herewith, you will find articles ranging from bioprospecting regional microalgae species, through advances in microalgae molecular physiology to the development of techniques for characterization of biomass and the use of biomass into agriculture and bioenergy production. This e-book is an excellent source of knowledge for those working with microalgae basic and applied sciences, and a great opportunity for researchers from both areas to have an overview of the amazing possibilities we have for building an environmentally sustainable future once the knowledge is translated into novel applications.
    Keywords: TA1-2040 ; TP248.13-248.65 ; QK1-989 ; Q1-390 ; Biotechnology ; biomass ; Hydrogen ; bioenergy ; Nutrients ; Lipids ; Microalgae ; Biofuels ; sustainability ; Carbon Dioxide ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
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  • 9
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    La rencontre pacifique de deux mondes chrétiens (2023)
    École française d’Athènes
    Details
    Publication Date: 2024-03-23
    Description: In publishing this book, an early version of which was first published under the auspices of the Academy of Athens, the French School at Athens highlights the research work of Aspasia Louvi-Kizi, an eminent specialist in the Frank and Byzantine Peloponnese, whose work reveals all of the complexity of the architectural forms, influences and models at work in the monuments of the medieval Byzantine city of Mystras. Out of all of the architecture created by the despotic couple formed by Manuel Cantacuzène (1349-1380) and his wife Isabelle de Lusignan, who were instrumental in turning Mystras into a centre of power, Aspasia Louvi-Kizi focuses on two of the city’s most iconic monuments, the monasteries of Peribleptos and Pantanassa, proposing a new history of their construction. Their architecture incorporates elements of Frank art, meaning western or gothic art, which were foreign to the local Byzantine tradition. The gothic aspect of Mystras’ architecture, as distinct from the Franco-Byzantine influences in the neighbouring crusader principality of Achaea, has more to do with Western art in Cyprus, and its introduction by Isabelle to the Peloponnese was to prove decisive. The Western elements that decorate the facades of clocks and towers, combined with the Byzantine features to constitute a concrete expression of the despotic couple’s pro-Western politics, in line with the imperial politics of Constantinople at the time. In the fragmented and multipolar world of the Eastern Mediterranean on the eve of the Ottoman conquest, this book highlights the role Mystras played as a centre of power in the region and, in doing so, contributes to a fresh take on the city as a whole. By continuing the international conversation about a renowned site, the French School at Athens shows its commitment to a multi-layered approach that reveals the complexity of the interactions at work in the history of the Greek world in transition.
    Keywords: Byzantine art ; Byzantine Empire ; crusade ; Gothic art ; Lusignan ; Christian art ; thema EDItEUR::A The Arts::AG The Arts: treatments and subjects::AGA History of art ; thema EDItEUR::6 Style qualifiers::6M Styles (M)::6MB Medieval style ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500
    Language: French
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  • 10
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    Sprachen der Wachsamkeit (2023)
    De Gruyter | De Gruyter
    Details
    Publication Date: 2024-03-24
    Description: This volume examines the linguistic dimension of vigilance in different contexts. The focus is on the social potentials, normative and regulative effects of languages as well as their use for marking dangers and orienting attention. This shows that language can be both an object and an instrument of vigilance and can itself become a medium of reflection of vigilance.
    Keywords: vigilance ; monitoring ; mindfulness ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFB Sociolinguistics ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTC Communication studies ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTD Semiotics / semiology ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history
    Language: English , German
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  • 11
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    Der lateinische ›Alexanderroman‹ des Iulius Valerius (2023)
    De Gruyter | De Gruyter
    Details
    Publication Date: 2024-03-27
    Description: Within the scope of the Greek-Latin Alexander romance, the Res gestae Alexandri Macedonis by Julius Valerius (early fourth century CE) stand out due to their high literary and stylistic standards. The eleven contributions in this edited volume primarily focus on issues of narrative technique, linguistic design, and intertextuality, thereby illustrating the unique features and rank of this often-neglected work in literary history.
    Keywords: Alexander the Great ; Iulius Valerius ; Middle Latin ; Late Antiquity ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general::DSBB Literary studies: ancient, classical and medieval ; thema EDItEUR::N History and Archaeology::NH History::NHC Ancient history ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500
    Language: German , English
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  • 12
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    Japan at War and Peace (2021)
    ANU Press | ANU Press
    Details
    Publication Date: 2024-04-02
    Description: The question of how to maintain the continuity of diplomacy while developing democracy without military intervention is an old and new issue. The challenge can be described as a dilemma between democracy and diplomatic coherence. This dilemma is not unique to the twenty-first century; it has been a constant challenge to the development of democracy. In non-Western countries, democratisation originated in the nineteenth century and has had many successes and failures. After the Russo-Japanese War, political parties began to take power in Japan. The best embodiment of diplomacy in Japan's emerging democracy—the development of parliamentary democracy and mass-based democracy—is Shidehara Kijūrō (1872–1951), who served as foreign minister from 1924 to 1927 and from 1929 to 1931, and was prime minister from 1945 to 1946. As a diplomat from the Ministry of Foreign Affairs, Shidehara had long grappled with the issue of how to ensure diplomatic coherence in modern Japan, which was becoming increasingly democratic. Although Shidehara succeeded to some extent in promoting diplomacy in cooperation with the US and the UK under party politics, the rise of the military after the Manchurian Incident forced him to retire for a period. However, after the Pacific War, Shidehara became prime minister of the US-occupied Japan and attempted to restore cooperative diplomacy under party politics. Shidehara came to the conclusion that the way to achieve both democracy and diplomatic coherence was through nonpartisan diplomacy towards peace. This book examines the tension between diplomacy and democracy, focusing on Shidehara’s life and exploring modern Japan’s footsteps. Shidehara was undoubtedly one of Japan’s most important diplomatic figures.
    Keywords: constitution ; War ; diplomacy ; Prime Minister ; Japan ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999::3MPQ Later 20th century c 1950 to c 1999 ; thema EDItEUR::N History and Archaeology::NH History::NHW Military history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSD Diplomacy
    Language: English
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  • 13
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    Contro frate Bernardino da Siena. Processi al maestro Amedeo Landi (Milano 1437-1447) (2021)
    Milano University Press
    Details
    Publication Date: 2024-04-01
    Description: The volume Contro Bernardino. Processi al maestro Amedeo Landi is the result of the discovery of unpublished documentation on the trials - only partly known - against the abacus master Amedeo Landi, who taught the Milanese merchants at the Broletto. This is an exceptional case not only because only one witness to the activity of the Milanese inquisitorial court in the Middle Ages (whose documentation has been entirely lost) was known until now, but also because of the role of the ecclesiastical court and its officials. The wealth of information and themes has prompted a team effort by the professors of the Department of Historical Studies to clarify the many aspects (political, religious, economic, documentary) of an event that shows the vitality of 15th-century Milan, in which the protagonist, the teacher Amedeo Landi, in an attempt to protect his students, clashes with the most important preacher of his time, Brother Bernardino of Siena, whose canonisation process is temporarily blocked precisely to shed light on the Milanese episode.
    Description: Published
    Description: Il volume Contro Bernardino. Processi al maestro Amedeo Landi nasce dal ritrovamento di documentazione inedita riguardo ai processi – solo in parte noti – contro il maestro d’abaco Amedeo Landi che insegnava ai mercanti milanesi presso il Broletto. Si tratta di un caso eccezionale non solo perché finora si conosceva un solo testimone dell’attività del tribunale inquisitoriale milanese nel medioevo (la cui documentazione è andata interamente perduta), ma anche per il ruolo del tribunale ecclesiastico e dei suoi funzionari. La ricchezza delle informazioni e dei temi ha suggerito un lavoro d’équipe dei docenti del Dipartimento di studi storici per chiarire i molteplici aspetti (politici, religiosi, economici, documentari) di una vicenda che mostra la vitalità della Milano quattrocentesca, in cui il protagonista, il maestro Amedeo Landi, nel tentativo di tutelare i suoi studenti si scontra con il più importante predicatore del suo tempo, frate Bernardino da Siena, il cui processo di canonizzazione viene momentaneamente bloccato proprio per fare luce sull’episodio milanese.
    Keywords: eresia ; mercanti ; Bernardino da Siena ; Amedeo Landi ; Milano medievale ; inquisizione ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500
    Language: Italian
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  • 14
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    Saberes tradicionais e locais : reflexões etnobiológicas (2021)
    SciELO Books - EDUERJ
    Details
    Publication Date: 2023-12-20
    Description: Durante séculos, diversos conhecimentos elaborados e mantidos por grupos sociais considerados à margem da sociedade receberam a classificação de conhecimento popular e conhecimento vulgar, o que demarcou o distanciamento entre esses saberes e o mundo das ciências. Este livro destaca, sob a perspectiva da etnobiologia, o potencial dos saberes tradicionais na construção de ações sustentáveis, refletindo sobre possíveis benefícios para a sociedade. Os autores oferecem análises e informações sobre a contribuição do conhecimento tradicional para a conservação da biodiversidade, para a segurança alimentar e para a saúde, por meio da utilização das plantas medicinais e de outras práticas nativas. O leitor vai perceber que, em muitos momentos, a imposição do mercado ou de pressões políticas não acarretou necessariamente uma melhoria real na alimentação ou na saúde da maior parte da população, como no exemplo dos problemas decorrentes de uma nutrição baseada em alimentos industrializados.
    Keywords: Q1-390 ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: Portuguese
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  • 15
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    The molecular pathology of cognitive decline: Focus on metals (2021)
    Frontiers Media SA
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    Publication Date: 2024-04-05
    Description: In the past two decades there have been significant advances made in understanding the cellular and molecular alterations that occur with brain ageing, as well as with our understanding of age-related brain diseases. Ageing is associated with a mid-life decline in many cognitive domains (eg. Attention, working memory, episodic memory) that progresses with advancing age and which may be potentiated by a variety of diseases. However, despite the breadth of attempts to explain it, the underlying basis for age-related memory impairment remains poorly understood. Both normal and “pathological” ageing (as in age-related neurodegenerative disorders such as Alzheimer’s disease) may be associated with overlapping and increased levels of “abnormal” pathology, and this may be a potential mediator of cognitive decline in both populations. An emerging hypothesis in this field is that metal ion dys/homeostasis may represent a primary unifying mechanism to explain age- and disease-associated memory impairment – either indirectly via an effect on disease pathogenesis, or by a direct effect on signaling pathways relevant to learning and memory. There remains a concerted worldwide effort to deliver an effective therapeutic treatment for cognitive decline associated with ageing and/or disease, which is currently an unmet need. There have been numerous clinical trials conducted specifically testing drugs to prevent cognitive decline and progression to dementia, but to date the results have been less than impressive, highlighting the urgent need for a greater understanding of the neurobiological basis of memory impairment in ageing and disease which can then drive the search for effective therapeutics.
    Keywords: RC321-571 ; Q1-390 ; Down Syndrome ; Amyotrophic Lateral Sclerosis ; Parkinson's disease ; aluminium ; Iron ; TBI ; Cognition ; Copper ; Alzheimer's disease ; Zinc ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 16
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    La stampa a Perugia nel Rinascimento (2022)
    FrancoAngeli
    Details
    Publication Date: 2024-04-01
    Description: The art of printing with movable type made its appearance in Perugia -then as now, the heart of Italy- in 1471, when the city was under the sway of Braccio Baglioni. Perugia was home to an important university which had been attracting students from all over Europe for more than a century. They found hospitality in two colleges, of which the ‘Sapienza Vecchia’, in particular, was accustomed to accommodating students from abroad. The colleges were themselves instrumental in assisting the work of the earliest printers, all of them foreigners; their enterprise flourished for about fifteen years before strong competition from larger printing centres, notably Venice, took control of the Perugian book market. A second phase in local book production started at the turn of the century under the aegis of two major players, the Cartolari family and Bianchino dal Leone. The history of the book in Perugia is characterized by a quality and originality which is not reflected in the modest quantities produced there, and the major bibliographers have always taken an interest in it. All that and more can be found in this book, the outcome of lengthy research based on detailed analysis of all known editions and archival documents, including a number of new discoveries.
    Keywords: Early Printed Books ; Incunabula ; History of University ; Renaissance ; Perugia ; History of the Book ; Printing Press ; Braccio Baglioni ; Book Illustration ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::W Lifestyle, Hobbies and Leisure::WQ Local and family history, nostalgia::WQH Local history ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics
    Language: Italian
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    Neuromorphic Engineering Systems and Applications (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Neuromorphic engineering has just reached its 25th year as a discipline. In the first two decades neuromorphic engineers focused on building models of sensors, such as silicon cochleas and retinas, and building blocks such as silicon neurons and synapses. These designs have honed our skills in implementing sensors and neural networks in VLSI using analog and mixed mode circuits. Over the last decade the address event representation has been used to interface devices and computers from different designers and even different groups. This facility has been essential for our ability to combine sensors, neural networks, and actuators into neuromorphic systems. More recently, several big projects have emerged to build very large scale neuromorphic systems. The Telluride Neuromorphic Engineering Workshop (since 1994) and the CapoCaccia Cognitive Neuromorphic Engineering Workshop (since 2009) have been instrumental not only in creating a strongly connected research community, but also in introducing different groups to each other’s hardware. Many neuromorphic systems are first created at one of these workshops. With this special research topic, we showcase the state-of-the-art in neuromorphic systems.
    Keywords: RC321-571 ; Q1-390 ; neuromorphic engineering ; Learning ; Floating gate ; Neural Network ; spike-based ; event-based ; simulation ; dynamic vision sensor ; network ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Abstract Mathematical Cognition (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Despite the importance of mathematics in our educational systems little is known about how abstract mathematical thinking emerges. Under the uniting thread of mathematical development, we hope to connect researchers from various backgrounds to provide an integrated view of abstract mathematical cognition. Much progress has been made in the last 20 years on how numeracy is acquired. Experimental psychology has brought to light the fact that numerical cognition stems from spatial cognition. The findings from neuroimaging and single cell recording experiments converge to show that numerical representations take place in the intraparietal sulcus. Further research has demonstrated that supplementary neural networks might be recruited to carry out subtasks; for example, the retrieval of arithmetic facts is done by the angular gyrus. Now that the neural networks in charge of basic mathematical cognition are identified, we can move onto the stage where we seek to understand how these basics skills are used to support the acquisition and use of abstract mathematical concepts.
    Keywords: RC321-571 ; Q1-390 ; Neuroimaging ; development ; numerosity ; gifted ; Mathematical Cognition ; algebra ; abstract ; Expertise ; Arithmetic ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Akten zur Auswärtigen Politik der Bundesrepublik Deutschland 1977 (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Keywords: D204-475 ; DD1-905 ; JA1-92 ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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    Understanding Selfies (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-03-29
    Description: In the year 2013, ‘selfie’ was named word of the year by Oxford Dictionaries in recognition of dramatic changes in frequency, prominence, and register of the term. This drastic increase in selfie-taking was spurred by two factors. The first was the advent of smartphones equipped with front cameras and preview screens that made it easy to compose a photographic self-portrait by a process of deliberately exploring one’s image, choosing a pose, and finally taking the picture. The second key change contributing to the rise of the selfie age was the increasing availability of internet connections. It is estimated that about 50% of the world population has access to the internet today (2018; https://www.internetworldstats.com). At the end of the past century, this percentage was a mere 1%. The growth of the internet infrastructure simultaneously spurred the development of social network applications such as Facebook, Twitter, Snapchat, and Instagram, providing accessible media for sharing photographs including photographic self-portraits. However, despite their tremendous reach and popularity, selfies have so far received relatively little attention by the scientific community, especially within psychology. Thus, we proposed a Frontiers in Psychology Research Topic to expand empirical and theoretical work on the massively popular, yet scientifically unexplored, phenomenon of the selfie. The articles published in this eBook offer a multifaceted insight into current scholarly work on this topic.
    Keywords: BF1-990 ; Q1-390 ; group selfies ; self-esteem ; Human Computer Interaction (HCI) ; self-presentation ; selfie ; viewing perspective ; perception bias ; smartphones ; social media ; internet ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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    The Jesuit Order as a Synagogue of Jews  (2021)
    Brill | Brill
    Details
    Publication Date: 2024-04-01
    Description: In The Jesuit Order as a Synagogue of Jews the author explains how Christians with Jewish ancestry went within less than forty years from having a leading role in the foundation and development of the Society of Jesus to being prohibited from membership in it. Readership: All those interested in converso and Jesuit history, the history of Catholicism, the history of late medieval and early modern Iberia and Italy, as well as Spanish literature historians, historians of law, and theologians.
    Keywords: History ; Jewish History & Culture ; Converso ; Ignatius of Loyola ; Rome ; Society of Jesus ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: English
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    European Monarchies from 1814 to 1906. A Century of Restorations (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Description: The year 2014 saw the 200th anniversary of Napoleon's downfall - and the restauration of the French monarchy under the house of Bourbon. With this as a starting point, Volker Sellin shows how the European monarchies restored and prolonged their reigns by giving their countries constitutions. This new angle results in an astonishing history of the 19th century in Europe from Spain to Russia.
    Keywords: D204-475 ; political legitimacy ; legal history ; constitutions ; Restauration ; monarchies ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: English
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    Les statuts communaux vus de l’extérieur dans les sociétés méditerranéennes de l’Occident (XIIe-XVe siècle) (2022)
    Éditions de la Sorbonne
    Details
    Publication Date: 2024-04-01
    Description: Ce volume est le quatrième d’une série d’ouvrages portant sur « Statuts, écritures et pratiques sociales dans les sociétés de la Méditerranée occidentale à la fin du Moyen Âge (XIIe-XVe siècle) », visant à étudier les statuts communaux dans une optique d’histoire sociale, non pas comme une source « normative » mais comme une source de la pratique, de leur matérialité et de leur forme d’écriture aux pratiques sociales en passant par les conditions de leur production et de conservation, leur inscription dans un paysage documentaire communal, leur structure et leur contenu. Ce dernier ouvrage s’intéresse aux statuts « vus de l’extérieur » c’est-à-dire au rapport entre le texte statutaire et sa mise en jeu dans des pratiques sociales concrètes, mais aussi à la manière dont les acteurs médiévaux se posent la question de l’usage de la norme, aux divers moments documentaires où ils font référence ou allèguent explicitement les statuts dans leurs pratiques. Il n’est donc question de statuts qu’à travers d’autres documents, qu’ils fassent partie du paysage documentaire communal (délibérations communales, registres de justice, registres de compte, criées, épigraphie, iconographie, etc.) ou qu’ils soient élaborés en marge des écrits de gouvernement (registres notariés, testaments, récits de miracles, procès de canonisation, sources narratives, chroniques, etc.). Le but est de repérer, d’analyser et d’étudier la manière dont les normes statutaires se sont diffusées – ou pas –, ont été appliquées – ou pas – dans les pratiques politiques, économiques et sociales de la commune : comment ont-elles été validées, reproduites, conservées, diffusées ? C’est l’occasion de mesurer la force pratique des statuts, leurs effets dans la vie quotidienne du gouvernement et des acteurs sociaux, de prouver ainsi la pertinence de la confrontation entre divers éléments textuels produits par la commune pour élaborer une histoire des pratiques sociales à partir des pratiques d’écriture dans les sociétés de la Méditerranée occidentale à la fin du Moyen Âge (XIIe-XVe siècle).
    Keywords: France ; ville ; Italie ; Méditerranée ; Occitanie ; statut ; administration communale ; droit communal ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500
    Language: French
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    Role of DNA Methyltransferases in the Epigenome (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-04-05
    Description: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Keywords: QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    The Margins of Late Medieval London, 1430-1540 (2022)
    University of London Press | Institute of Historical Research | University of London Press
    Details
    Publication Date: 2024-04-01
    Description: The Margins of Late Medieval London is a powerful study of medieval London’s urban fringe. Seeking to unpack the complexity of urban life in the medieval age, this volume offers a detailed and novel approach to understanding London beyond its institutional structures. Using a combination of experimental digital, quantitative and qualitative methodologies, the volume casts new light on urban life at the level of the neighbourhood and considers the differences in economy, society and sociability which existed in different areas of a vibrant premodern city. It focuses on the dynamism and mobility that shaped city life, integrating the experiences of London’s poor and migrant communities and how they found their place within urban life. It describes how people found themselves marginalized in the city, and the strategies they would employ to mitigate that precarious position.
    Keywords: middle ages ; marginality ; capital city ; poverty ; London ; London poor ; begging ; refugees ; medieval London ; disease ; prostitution ; sewage ; countryside ; migrant ; migration ; workers ; labour ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500
    Language: English
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    Genome-wide view on the physiology of vitamin D (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-03-31
    Description: The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydroxyvitamin D3(1a,25(OH)2D3), are calcium and phosphorus uptake and transport and thereby controlling bone formation. Other emergent areas of 1a,25(OH)2D3 action are in the control of immune functions, cellular growth and differentiation. This fits both with the widespread expression of the VDR and the above described consequences of vitamin D deficiency. Transcriptome-wide analysis indicated that per cell type between 200 and 600 genes are primary targets of vitamin D. Since most of these genes respond to vitamin D in a cell-specific fashion, the total number of vitamin D targets in the human genome is far higher than 1,000. This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980’s. Thus, vitamin D signaling primarily implies the molecular actions of the VDR. In this research topic, we present in 15 chapters different perspectives on the action of vitamin D and its receptor, such as the impact of the genomewide distribution of VDR binding loci, ii) the transcriptome- and proteome-wide effects of vitamin D, iii) the role of vitamin D in health, iv) tissue-specific functions of vitamin D and v) the involvement of vitamin D in different diseases, such as infections, autoimmune diseases, diabetes and different types of cancer.
    Keywords: QP1-981 ; Q1-390 ; Vitamin D ; Immune System ; Genomics ; vitamin D receptor ; Physiology ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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    La ciudad de los monos Roberto Brenes Mesén, los católicos heredianos y el conflicto cultural de 1907 en Costa Rica (2021)
    Editorial Universidad Nacional (EUNA)
    Details
    Publication Date: 2024-04-01
    Description: In 1907, the city of Heredia became the epicenter of the most important religious conflict experienced by Costa Rica in the 20th century. A complaint that the theory of evolution was being taught in the Lyceum (i.e. secondary school) of that city, triggered an increasingly intense confrontation between the Catholic parishioners and the circle of young radical intellectuals articulating around the writer and educator Roberto Brenes Mesén. In the course of this process, Costa Rican society, to the alarm of the government of Cleto González Víquez, was the scene of popular mobilizations in defense of the faith, excommunications and burning of impious texts, while Catholic morality was systematically questioned based on sexual abuse attributed to priests. For a moment, it seemed that the country had gone back in time, and that the ghosts of 1884 were present.
    Keywords: Heredia (Costa Rica) – History – 1907 ; Catholic Church – Heredia (Costa Rica) ; Brenes Mesén, Roberto, 1874-1947 ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999 ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history
    Language: Spanish
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    Sobreviure a les presons de Franco: Testimoni epistolar de 1939 a 1943 (2021)
    Publicacions Universitat Rovira i Virgili
    Details
    Publication Date: 2024-04-01
    Description: Aquest estudi sobre la presó franquista de postguerra es basa en les duescentes quaranta cartes que Daniel Vilaró Rius va escriure a la seva família entre juliol del 1939 i agost del 1943 des de tres presons i, per tant, presenta el règim penitenciari viscut des de dins. En aquestes cartes trobem en primera persona l’impacte psicològic de la derrota, dels judicis sumaríssims i de l’empresonament, la por i la incertesa de cada dia, la penúria, la privació emocional de l’allunyament de la família, la frustració de no poder exercir cap rol familiar. Alhora, la voluntat de sobreviure física i moralment, que va ser una voluntat política, i els mecanismes i estratègies que van fer que molts ho aconseguissin, des de l’ajut de fora i la solidaritat a dins, fins a la capacitat de cadascú per mantenir alguna il·lusió i la fe en el futur.
    Keywords: D204-475 ; Guerra Civil espanyola ; presons ; franquisme ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: Catalan
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    Geoturismo e interpretação ambiental (2021)
    SciELO Books - Editora UEPG
    Details
    Publication Date: 2023-12-20
    Description: Dividido em três partes, este livro enfoca o turismo em áreas naurais, destacando o geoturismo, abrange aspectos ligados à geoconservação em áreas protegidas e os Geoparques e por fim aborda a educação e interpretação ambiental, incluindo diversos exemplos de atividades geoeducativas, interpretativas e turísticas.
    Keywords: Q1-390 ; SCIENCE ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: Portuguese
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    The Role of Glia in Plasticity and Behavior (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Glial cells are no longer considered passive bystanders in neuronal brain circuits. Not only are they required for housekeeping and brain metabolism, they are active participants in regulating the physiological function and plasticity of brain circuits and the online control of behavior both in invertebrate and vertebrate model systems. In invertebrates, glial cells are essential for normal function of sensory organs (C. elegans) and necessary for the circadian regulation of locomotor activity (D. melanogaster). In the mamallian brain, astrocytes are implicated in the regulation of cortical brain rhythms and sleep homeostasis. Disruption of AMPA receptor function in a subset of glial cell types in mice shows behavioral deficits. Furthermore, genetic disruption of glial cell function can directly control behavioral output. Regulation of ionic gradients by glia can underlie bistability of neurons and can modulate the fidelity of synaptic transmission. Grafting of human glial progenitor cells in mouse forebrain results in human glial chimeric mice with enhanced plasticity and improved behavioral performance, suggesting that astrocytes have evolved to cope with information processing in more complex brains. Taken together, current evidence is strongly suggestive that glial cells are essential contributors to information processing in the brain. This Research Topic compiles recent research that shows how the molecular mechanisms underlying glial cell function can be dissected, reviews their impact on plasticity and behavior across species and presents novel approaches to further probe their function.
    Keywords: RC321-571 ; Q1-390 ; Cerebellum ; C. elegans ; Astrocytes ; DREADD ; Cortex ; plasticity ; Gq ; Behavior ; glia ; Hippocampus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Avenir du fleuve Niger (2021)
    IRD Éditions
    Details
    Publication Date: 2023-12-20
    Description: Le fleuve Niger constitue un véritable poumon humide pour l’Afrique de l’Ouest et plus spécialement pour la république du Mali. Dans ce pays, la gestion du fleuve constitue un enjeu majeur car on y trouve à la fois de remarquables systèmes de production traditionnels associés au phénomène naturel de crue – sources de moyens d’existence pour des centaines de milliers de personnes – mais aussi de grandes réalisations et promesses en matière d’aménagements modernes, hydroélectriques et hydroagricoles. À l’heure où de nouveaux projets d’équipement arrivent à concrétisation et où d’autres sont annoncés, il est important de faire le point sur l’état de santé de ce fleuve et de peser ce qu’il représente pour ses multiples usagers. Cette expertise collégiale, conduite par l’IRD et l’IER et réalisée avec le soutien de plusieurs institutions d’aide au développement et de défense de l’environnement, traite de ces différents aspects avec pour objectif, d’une part, la clarification des cadres institutionnels et des options de politiques publiques et, d’autre part, le renforcement des outils de suivi et d’aide à la décision.
    Keywords: Q1-390 ; aménagement hydroélectrique ; écosystème ; irrigation ; Niger cours d’eau ; aménagement hydroagricole ; Mali ; exploitation des ressources naturelles ; eau ; bassin versant ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: French
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    Ricerche sull'organizzazione del territorio nella Liguria medievale (2021)
    Firenze University Press
    Details
    Publication Date: 2024-04-01
    Description: The organisation of the territory is the outcome of strategies of varying scope, in which a number of agents interact to shape out the areas of operation. The Liguria reality is probed here through four different situations - separated in chronological terms but sharing the poor visibility and limited efficacy of the fortified settlements. These focus on Genoa, both in the definition of its hinterland between the tenth and the eleventh centuries, and in establishing the bulwarks of coastal territorial expansion in the twelfth; the powerful groups of feudal lords who remoulded the rural settlement layout in the thirteenth century; finally, a village of the hinterland explored right through to the modern age.
    Keywords: D111-203 ; Comuni medievali ; Open Access ; Storia ; Societ&agrave ; Liguria ; Signorie ; Medioevo ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500
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    Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-04-05
    Description: Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies is a Special Issue of the International Journal of Neonatal Screening. Sickle cell disease is one of the most common inherited blood disorders, with a huge impact on health care systems due to high morbidity and high mortality associated with the undiagnosed disease. Newborn screening helps to make the diagnosis early and to prevent fatal complications and diagnostic odysseys. This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.
    Keywords: QD1-999 ; Q1-390 ; glucose-6-phosphate dehydrogenase ; hydroxyurea/hydroxycarbamide ; n/a ; cord blood ; screening ; hemoglobin pattern ; capillary electrophoresis ; sickle cell disease ; (recommended) screening panel ; vaso-occlusive crisis ; Guthrie spots ; newborn screening) ; foetal haemoglobin ; harmonisation ; review ; birth prevalence ; G6PD deficiency ; prevention ; end-organ damage ; thalassemia ; MALDI-TOF ; IEF ; acute chest syndrome ; India ; sickle cell and thalassaemia screening programme ; ‘Getting to Outcomes’ ; newborn screening ; hemoglobinopathy ; service users ; public health engagement ; automated HPLC ; Kaduna State ; gene therapy for haemoglobinopathies ; ?-globin gene ; methods ; neonatal screening program ; malaria ; Plasmodium vivax ; sub-Saharan Africa ; patient organisations ; health policy ; pathophysiology ; Sickle Cell Disease ; mass spectrometry ; sickle cell disorder ; neonatal screening ; non-tribal ; Nigeria ; point-of-care ; HPLC ; laboratory methods ; registry ; patient advocacy ; bone marrow transplant ; anaemia ; hemoglobinopathies ; tribal ; newborn ; burden of disease ; patient representatives ; diagnostics ; policy making ; haemolysis ; Caribbean ; high performance liquid chromatography (HPLC) ; sickle cell disease (SCD) ; implementation science ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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    Between State and Church (2021)
    Peter Lang International Academic Publishing Group
    Details
    Publication Date: 2024-04-01
    Description: The different theoretical notions and practices of the relations between the state and religious communities in early modern Europe constitute one of the most interesting problems in historiography. Moving away from a simple «toleration» versus «non-toleration» dichotomy, the author sets out to analyse the inter-confessional relations in selected European territories in a «longue duree» perspective, between Reformation and Enlightenment. Outlining the relations between the state and the different Churches (confessions) in the Polish-Lithuanian Commonwealth, the Holy Roman Empire of Germany, and the Northern Netherlands serves to highlight the specificity of Northern Netherlands serves to highlight the specificity of «free» (non-absolutist) composite states, where the particularly complex process of defining the raison d’etat determined the level of religious toleration that was politically feasible and socially acceptable.
    Keywords: Church ; Church-state relations ; Confessional ; Denominational relations ; Enlightenment ; Germany ; Humanist and political theory ; Kriegseisen ; Lithuania ; Netherlands ; Poland ; Protestant and Catholic reformers ; Reform ; Reformation ; Relations ; State ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::J Society and Social Sciences::JP Politics and government
    Language: English
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    Manipulative approaches to human brain dynamics (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: In this EBook, we highlight how newly emerging techniques for non-invasive manipulation of the human brain, combined with simultaneous recordings of neural activity, contribute to the understanding of brain functions and neural dynamics in humans. A growing body of evidence indicates that the neural dynamics (e.g., oscillations, synchrony) are important in mediating information processing and networking for various functions in the human brain. Most of previous studies on human brain dynamics, however, show correlative relationships between brain functions and patterns of neural dynamics measured by imaging methods such as electroencephalography (EEG), magnetoencephalography (MEG), near-infrared spectroscopy (NIRS), positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). In contrast, manipulative approaches by non-invasive brain stimulation (NIBS) have been developed and extensively used. These approaches include transcranial magnetic stimulation (TMS) and transcranial electric stimulation (tES) such as transcranial direct current stimulation (tDCS), alternating current stimulation (tACS), and random noise stimulation (tRNS), which can directly manipulate neural dynamics in the intact human brain. Although the neural-correlate approach is a strong tool, we think that manipulative approaches have far greater potential to show causal roles of neural dynamics in human brain functions. There have been technical challenges with using manipulative methods together with imaging methods. However, thanks to recent technical developments, it has become possible to use combined methods such as TMS–EEG coregistration. We can now directly measure and manipulate neural dynamics and analyze functional consequences to show causal roles of neural dynamics in various brain functions. Moreover, these combined methods can probe brain excitability, plasticity and cortical networking associated with information processing in the intact human brain. The contributors to this EBook have succeeded in showcasing cutting-edge studies and demonstrate the huge impact of their approaches on many areas in human neuroscience and clinical applications.
    Keywords: RC321-571 ; Q1-390 ; non-invasive brain stimulation NIBS ; TMS-EEG ; Transcranial magnetic stimulation TMS ; transcranial electric stimulation tES ; Coregistration ; Near-infrared spectroscopy NIRS ; Functional magnetic resonance imaging fMRI ; transcranial direct current stimulation tDCS ; transcranial alternating current stimulation tACS ; transcranial random noise stimulation tRNS ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    The enigma of Balint's syndrome: complexity of neural substrates and cognitive deficits (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Bálint’s syndrome is named after the Hungarian physician who first reported a remarkable case of a man with complex visuospatial deficits following bilateral lesions within parietal and occipital cortex (Bálint, 1909). The syndrome has three primary symptoms: simultanagnosia (impaired spatial awareness of more than one object at time), optic ataxia (misreaching to visual targets) and ocular apraxia (described by Bálint as “psychic paralysis of gaze”). Balint’s patients not only cannot perceive more than one object at time and therefore show poor comprehension of multi-object visual scenes i.e. poor detection of all the objects present and difficulty in grasping the relationship between them; in addition they typically fail to reach towards location of the single object, which they can perceive. The deficit of the allocation of spatial attention in Balint’s syndrome has been linked to a problem in feature binding which results in illusory conjunctions. Patients with Balint’s syndrome also show deficits in global processing i.e. when integration of multiple local elements into global compound shapes is required. Consequently, Balint’s syndrome provides a unique opportunity to study the nature and neuroanatomy of human visuospatial processing, in particular multi-level object representation, spatial awareness and the distribution of visual attention. The studies collected here cover both the anatomical and the cognitive mechanisms of the different symptoms associated with the syndrome. Furthermore, the dissociations between the components of Bálints’ syndrome, in particular simultanagnosia and optic ataxia, can also co-occur with visual neglect and extinction and the different combinations of reported lesions raises a question about the status of the syndrome and whether it should be merely treated as a historical compilation of symptoms which may or may not coexist cohesively. This interesting argument is raised here.
    Keywords: RC321-571 ; Q1-390 ; posterior cortical atrophy ; Balints syndrome ; optic ataxia ; Posterior parietal cortex ; simultanagnosia ; ocular apraxia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Ca2+ and Ca2+-interlocked Membrane Guanylate Cyclase Modulation (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: The tale of cyclic GMP has been astonishing. Having overcome an initial disbelief, cyclic GMP has risen to its present eminence as a premium cellular signal transduction messenger of not only hormonal extracellular but also of the intracellular signals. This research topic focuses on the pathways and functions of membrane guanylate cyclases in different tissues of the body and their interplay with intracellular sensory signals where in many cases, cyclic GMP along with Ca2+ have taken on roles as synarchic co-messengers.
    Keywords: RC321-571 ; Q1-390 ; Glaucoma ; Visceral Pain ; Calcium ; membrane guanylate cyclase ; ANF-RGC ; Gene Therapy ; Cyclic GMP ; synaptic plasticity ; trafficking ; ROS-GC ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Noble conceptions of politics in eighteenth-century Sweden (ca 1740–1790) (2021)
    Finnish Literature Society / SKS
    Details
    Publication Date: 2024-04-01
    Description: "Noble conceptions of politics in eighteenth-century Sweden (ca 1740–1790) is a study of how the Swedish nobility articulated its political ideals, self-images and loyalties during the Age of Liberty and under the rule of Gustav III. This book takes a close look at the aristocracy’s understanding of a free constitution and at the nobility’s complex relationship with the monarchy. Central themes are the old notion of mixed government, classical republican conceptions of liberty and patriotism, as well as noble thoughts on the rights and duties of the citizen, including the right to rebellion against an unrighteous ruler. The study is a conceptual analysis of public and private political statements made by members of the nobility, such as Diet speeches and personal correspondence. The book contributes to the large body of research on estate-based identities and the transformation of political language in the second half of the eighteenth century by connecting Swedish political ideals and concepts to their European context."
    Keywords: upper class ; identity (mental qualities) ; political elite ; ideals ; systems of government ; nobility ; Age of Liberty ; Autocracy ; Finland ; Gustav III of Sweden ; Stockholm ; Sweden ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: English
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    Beyond Exceptionalism (2021)
    De Gruyter | De Gruyter Oldenbourg
    Details
    Publication Date: 2024-04-02
    Description: While the economic involvement of early modern Germany in slavery and the slave trade is increasingly receiving attention, the direct participation of Germans in human trafficking remains a blind spot in historiography. This edited volume focuses on practices of enslavement taking place within German territories in the early modern period as well as on the people of African, Asian, and Native American descent caught up in them.
    Keywords: Slavery ; Germany ; Atlantic history ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHB General and world history ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTQ Colonialism and imperialism ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTR National liberation and independence ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTS Slavery and abolition of slavery
    Language: English
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    The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervous system. Ion channels are the large proteins that form regulated pores in the membranes of cells and, in the brain, are essential for the transfer, processing and storage of information. These pores full of twists and turns themselves are not just barren bridges into cells. More and more we are beginning to understand that ion channels are like bustling medieval bridges (packed with apartments and shops) rather than the more sleek modern variety – they are dynamic hubs connected with many structures facilitating associated activities. Our understanding of these networks continues to expand as our investigative tools advance. Together these articles highlight how the complexity of ion channel signaling nexuses is critical to the proper functioning of the nervous system.
    Keywords: RC321-571 ; Q1-390 ; Nervous System ; Ion Channels ; Interactome ; cellular signaling ; Protein complexes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Novel Approaches to the Analysis of Family Data in Genetic Epidemiology (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer.
    Keywords: QH426-470 ; Q1-390 ; Regional heritability ; prostate cancer ; infectious diseases ; MCMC ; combining studies screening ; conditional-logistic linkage ; Informatics ; autism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Language: English
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    Pathologic Conditions of the Human Nervous and Muscular Systems Associated with Mutant Chaperones: Molecular and Mechanistic Aspects (2021)
    Frontiers Media SA
    Details
    Publication Date: 2022-01-31
    Description: This eBook presents illustrative examples of genetic chaperonopathies affecting primarily nerves and muscles and discusses molecular mechanisms and treatment targeting chaperones, i.e., chaperonotherapy.
    Keywords: Q1-390 ; small-Hsp ; Hsp60/CCT/BBS ; Indirect/Secondary Chaperonopathies ; Genetic Chaperonopathies ; Hsp40/DnaJ ; chaperonotherapy
    Language: English
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    Pathophysiology and epidemiology of virus-induced asthma (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Virus-caused asthma, we now call a phenotype of asthma. Regardless of the significance and popularity of this disease, the etiology of the virus-induced asthma have not well understood. In addition, a few effective vaccines have been applied to prevent respiratory virus infection. To solve the issues, it is essential to clarify and delineate both aspects of the virus and host defense systems including acute/chronic inflammation and airway tissue remodeling. To deeply review and discuss pathophysiology and epidemiology of virus-induced asthma, this topics includes new findings of the host immunity, pathology, epidemiology, and virology of asthma/chronic obstructive pulmonary disease (COPD). We believe that these works are well summarized and informative to glimpse the field of virus- associated asthma and COPD, and may help understanding the basic and clinical aspects of the diseases.
    Keywords: QR1-502 ; QK1-989 ; Q1-390 ; virus-induced asthma ; Pathology ; respiratory virus ; human immunity ; Epidemiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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    Auf die Tour!: Jüdinnen und Juden in Singspielhalle, Varieté und Kabarett – Habsburgermonarchie bis Amerika (2021)
    Böhlau
    Details
    Publication Date: 2024-04-01
    Description: In the monography Auf die Tour, I analyze the participation of Jews in popular culture in Vienna, Budapest and New York. I argue that entertainment in vaudevilles was shaped between the perception of difference and similarity, between human trafficking, covert prostitution, anti-Semitism and nationalism. Ultimately, my research shows how a space for Jewish-non-Jewish people was created in the coinciding of the mass migration movement and the emerging mass culture between the Habsburg Monarchy and the United States.
    Description: Auf die Tour berichtet von der Teilhabe von Jüdinnen und Juden an der populären Kultur in Wien, Budapest und New York. Zwischen Differenzwahrnehmungen und Ähnlichkeitsdenken, zwischen Menschenhandel, verdeckter Prostitution, Antisemitismus und Nationalismus gestaltete sich Unterhaltung in Varietés. Meine Forschung zeigt, wie sich ein Raum für jüdisch-nichtjüdische Begegnungen in der Massenmigrationsbewegung und der entstehenden Massenkultur zwischen der Habsburgermonarchie und den Vereinigten Staaten ergab.
    Keywords: Jews, fin-de-siècle, Jewish and non-Jewish Relations, cultural exchange, Habsburg Empire, popular entertainment, Vienna, Budapest, New York ; ÖFOS 2012, Regional history ; ÖFOS 2012, Cultural studies ; ÖFOS 2012, Gender studies ; ÖFOS 2012, Global history ; Jüdinnen und Juden, jüdisch-nichtjüdische Beziehungen, kultureller Austausch, Jahrhundertwende, Habsburgermonarchie, Populärkultur, Wien, Budapest, New York ; ÖFOS 2012, Regionalgeschichte ; ÖFOS 2012, Kulturwissenschaft ; ÖFOS 2012, Gender Studies ; ÖFOS 2012, Globalgeschichte ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999 ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSR Social groups: religious groups and communities ; thema EDItEUR::5 Interest qualifiers::5P Relating to specific groups and cultures or social and cultural interests::5PG Relating to religious groups::5PGJ Relating to Jewish people and groups
    Language: German
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    Le mouvement hibiste (2023)
    Presses universitaires de Rennes
    Details
    Publication Date: 2024-04-02
    Description: Au début du siècle dernier, le sultan du Maroc vient de signer un traité qui place désormais son pays sous le protectorat de la France (30 mars 1912). À l’ombre du maréchal Lyautey, un sultan de substitution, totalement soumis aux nouveaux maîtres français, a été proclamé. Cependant, nombreux sont ceux qui, au Maroc, refusent le fait accompli et se révoltent face à la mainmise étrangère sur le pays. Ainsi, dans le Sud marocain, Moulay Ahmed el Hiba, fils d’un marabout ouest-saharien (Ma el Aïnin), se fait proclamer sultan du Jihad en 1912 ; une première fois à Tiznit, la seconde à Marrakech. Ces événements ont donné naissance à un mouvement qui pendant plus de vingt ans (1912-1934) symbolisera pour ces populations berbères et ouest-sahariennes la résistance à l’avancée inéluctable des troupes coloniales françaises et espagnoles. Fondée sur une analyse croisée d’archives inédites, aussi bien françaises que marocaines, l’auteur fait la lumière sur un événement fondateur de la conquête coloniale du Maroc. Mythifiée, récupérée ou occultée, la figure fondatrice du mouvement hibiste est encore aujourd’hui le sujet d’un conflit mémoriel ayant pour objet l’Ouest saharien.
    Keywords: Berbères ; colonialisme ; protectorat ; thema EDItEUR::N History and Archaeology::NH History::NHH African history ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999
    Language: French
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    Transfer Cells (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Transfer cells are anatomically specialized cells optimized to support high levels of nutrient transport in plants. These cells trans-differentiate from existing cell types by developing extensive and localized wall ingrowth labyrinths to amplify plasma membrane surface area which in turn supports high densities of membrane transporters. Unsurprisingly, therefore, transfer cells are found at key anatomical sites for nutrient acquisition, distribution and exchange. Transfer cells are involved in delivery of nutrients between generations and in the development of reproductive organs and also facilitate the exchange of nutrients that characterize symbiotic associations. Transfer cells occur across all taxonomic groups in higher plants and also in algae and fungi. Deposition of wall ingrowth-like structures are also seen in “syncytia” and “giant cells” which function as feeding sites for cyst and root-knot nematodes, respectively, following their infection of roots. Consequently, the formation of highly localized wall ingrowth structures in diverse cell types appears to be an ancient anatomical adaption to facilitate enhanced rates of apoplasmic transport of nutrients in plants. In some systems a role for transfer cells in the formation of an anti-pathogen protective barrier at these symplastic discontinuities has been inferred. Remarkably, the extent of cell wall ingrowth development at a particular site can show high plasticity, suggesting that transfer cell differentiation might be a dynamic process adapted to the transport requirements of each physiological condition. Recent studies exploiting different experimental systems to investigate transfer cell biology have identified signaling pathways inducing transfer cell development and genes/gene networks that define transfer cell identity and/or are involved in building the wall ingrowth labyrinths themselves. Further studies have defined the structure and composition of wall ingrowths in different systems, leading in many instances to the conclusion that this process may involve previously uncharacterized mechanisms for localized wall deposition in plants. Since transfer cells play important roles in plant development and productivity, the latter being relevant to crop yield, especially so in major agricultural species such as wheat, barley, soybean and maize, understanding the molecular and cellular events leading to wall ingrowth deposition holds exciting promise to develop new strategies to improve plant performance, a key imperative in addressing global food security. This Research Topic presents a timely and comprehensive treatise on transfer cell biology to help define critical questions for future research and thereby generating a deeper understanding of these fascinating and important cells in plant biology.
    Keywords: QK1-989 ; Q1-390 ; Wall ingrowth ; Arabidopsis thaliana ; synctial cells ; Zea mays ; transfer cells ; endosperm transfer cells ; Giant Cells ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Language: English
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    Neuroendocrine mechanisms that connect feeding behavior and stress (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Research during the past decade highlights the strong link between appetitive feeding behavior, reward and motivation. Interestingly, stress levels can affect feeding behavior by manipulating hypothalamic circuits and brain dopaminergic reward pathways. Indeed, animals and people will increase or decrease their feeding responses when stressed. In many cases acute stress leads to a decrease in food intake, yet chronic social stressors are associated to increases in caloric intake and adiposity. Interestingly, mood disorders and the treatments used to manage these disorders are also associated with changes in appetite and body weight. These data suggest a strong interaction between the systems that regulate feeding and metabolism and those that regulate mood. This Research Topic aims to illustrate how hormonal mechanisms regulate the nexus between feeding behavior and stress. It focuses on the hormonal regulation of hypothalamic circuits and/or brain dopaminergic systems, as the potential sites controlling the converging pathways between feeding behavior and stress.
    Keywords: RC321-571 ; Q1-390 ; stress ; Obesity ; Dopamine ; Ghrelin ; Leptin ; Seasonal regulation ; feeding ; HPA axis ; Hypothalamus ; circadian rhythms ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Enteric Viruses in Aquatic Environments (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2023-12-20
    Description: This Special Issue contains one review and five original articles, all of which address cutting-edge research in the field of water and environmental virology. The review article by Gerba and Betancourt summarizes the current status and future needs for the development of virus detection methods in water reuse systems, especially focusing on methods to assess the infectivity of enteric viruses. Original papers cover a variety of research topics, such as an environmental monitoring survey of group A rotaviruses in sewage and oysters in Japan, the occurrence and genetic diversity of noroviruses and rotaviruses in a wastewater reclamation system in China, the detection of viruses and their indicators in tanker water and its sources in Nepal, integrated culture next-generation sequencing to identify the diversity of F-specific RNA coliphages in wastewater, and the development of a portable collection and detection method for viruses from ambient air and its application to a wastewater treatment plant.
    Keywords: Q1-390 ; reuse ; aerosols ; viral indicator ; wastewater treatment ; microbial contamination ; index virus ; real-time PCR ; tanker water ; virus ; wastewater reclamation ; pathogenic virus ; infectivity ; chlorination ; molecular methods ; wastewater ; next-generation sequencing ; fecal source tracking ; oyster ; fecal-source marker ; viral contamination ; cell culture ; pathogenic microorganisms ; rotavirus ; ultraviolet disinfection ; F-specific RNA bacteriophage strain ; sewage ; waterborne gastroenteritis viruses ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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    The Clinical and Ethical Practice of Neuromodulation - Deep Brain Stimulation and Beyond (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: euromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
    Keywords: RC321-571 ; Q1-390 ; Informed Consent ; Deep Brain Stimulation ; Depression ; Neurosurgery ; Movement Disorders ; Neuromodulation ; Enhancement ; Neuroethics ; Philosophy ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Zeitgeschichte in Lebensbildern Band 12 (2024)
    Aschendorff Verlag | Aschendorff Verlag
    Details
    Publication Date: 2024-04-01
    Description: Volume 12 contains the biographies of Rainer Barzel (1924-2006), Alfred Dregger (1920-2002), Johannes Dyba (1929-2000), Hermann von Grauert (1850-1924), Paulus van Husen (1891-1971), Richard Jaeger (1913-1998), Thusnelda Lang-Brumann (1880-1953), Amalie Lauer (1882-1950), Franz Meyers (1908-2001), Hermann Platz (1880-1945), Otto B. Roegele (1920-2005), Wilfried Schreiber (1904-1975), Josef Stingl (1919-2004), Arthur F. Utz (1908-2001), Hermann Kardinal Volk (1903-1988), Wilhelm Weber (1925-1983).
    Keywords: history ; biography ; catholic personalities ; german personalities ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999
    Language: German
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    Multisensory Integration in Action Control (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-03-29
    Description: The integration of multisensory information is an essential mechanism in perception and in controlling actions. Research in multisensory integration is concerned with how the information from the different sensory modalities, such as the senses of vision, hearing, smell, taste, touch, and proprioception, are integrated to a coherent representation of objects. Multisensory integration is central for action control. For instance, when you grasp for a rubber duck, you can see its size and hear the sound it produces. Moreover, identical physical properties of an object can be provided by different senses. You can both see and feel the size of the rubber duck. Even when you grasp for the rubber duck with a tool (e.g. with tongs), the information from the hand, from the effect points of the tool and from the eyes are integrated in a manner to act successfully. Over the recent decade a surge of interest in multisensory integration and action control has been witnessed, especially in connection with the idea that multiple sensory sources are integrated in an optimized way. For this perspective to mature, it will be helpful to delve deeper into the information processing mechanisms and their neural correlates, asking about the range and constraints of this mechanisms, about its localization and involved networks.
    Keywords: BF1-990 ; Q1-390 ; recalibration ; haptic ; Human Information Processing ; Vision ; Perception ; reference frame ; Acoustics ; Tool Use ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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    Augmentation of Brain Function: Facts, Fiction and Controversy. Volume I: Brain-Machine Interfaces (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Volume I, entitled “Augmentation of Brain Functions: Brain-Machine Interfaces”, is a collection of articles on neuroprosthetic technologies that utilize brain-machine interfaces (BMIs). BMIs strive to augment the brain by linking neural activity, recorded invasively or noninvasively, to external devices, such as arm prostheses, exoskeletons that enable bipedal walking, means of communication and technologies that augment attention. In addition to many practical applications, BMIs provide useful research tools for basic science. Several articles cover challenges and controversies in this rapidly developing field, such as ways to improve information transfer rate. BMIs can be applied to the awake state of the brain and to the sleep state, as well. BMIs can augment action planning and decision making. Importantly, BMI operations evoke brain plasticity, which can have long-lasting effects. Advanced neural decoding algorithms that utilize optimal feedback controllers are key to the BMI performance. BMI approach can be combined with the other augmentation methods; such systems are called hybrid BMIs. Overall, it appears that BMI will lead to many powerful and practical brain-augmenting technologies in the future.
    Keywords: RC321-571 ; Q1-390 ; microcircuits ; Brain machine interface (BMI) ; nootropics ; tDCStranscranial direct current stimulation ; neural networks ; neuroprosthesis ; TMS ; implants ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Mary Shelley et le baiser : figures romantiques ? (2023)
    UGA Éditions
    Details
    Publication Date: 2024-04-01
    Description: La figure du baiser occupe une place de choix dans les romans de Mary Shelley (1797-1851), femme de lettres anglaise traditionnellement attachée au courant romantique. Cet ouvrage veut contribuer à la connaissance, encore trop peu développée en France, de cette romancière, par le biais d’une figure littéraire qui entretient un rapport fort à la littérature en général et au romantisme en particulier. Il s’agira d’étudier les modalités de la représentation du baiser dans les sept romans que Mary Shelley produisit entre 1818 et 1837. Figure de la rencontre de deux subjectivités, le baiser se décline sur un mode sensible, mythique et philosophique chez la romancière. Au terme de ce parcours, c’est une figure bien particulière de l’écrivain qui sera (re)découverte.
    Keywords: Frankenstein ; érotique ; esthétique ; éthique ; XIXe siècle ; romancière britannique ; les précieuses ; baiser ; romantisme anglais ; romantique ; littérature féminine ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: French
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    Working At Night (2022)
    De Gruyter | De Gruyter Oldenbourg
    Details
    Publication Date: 2024-04-01
    Description: The night has always and almost universally represented a special ‘out of the ordinary’ temporal zone with its own meanings, possibilities, and dangers. It is only since the modern era that the night has become increasingly ‘normalised’. Although 24/7 industrial production is often seen as a consequence of capitalist expansion, other political and economic regimes adopted the ‘night shift’, normalising it as part of an alternative modernity.
    Keywords: night shift work ; industrial labour ; labour history ; modernity ; 24/7. ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999 ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTK Industrialisation and industrial history
    Language: English
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    Athanasius Raczyński (1788–1874). Aristocrat, Diplomat, and Patron of the Arts (2024)
    Brill
    Details
    Publication Date: 2024-03-23
    Description: This book depicts the long rich life and wide ranging work of Count Athanasius Raczyński (1788–1874). By exploring his complex personality, his processes of thought and his accomplishments, it reveals a man at once a wealthy aristocrat, a Pole in the Prussian diplomatic service, an active participant in and perceptive observer and critical commentator on political life, a connoisseur and art collector of European renown, and the author of ground breaking studies on German and Portuguese art – in short a distinguished and fascinating nineteenth century figure.
    Keywords: 19th-century Berlin ; aristocracy ; art collecting ; art historiography ; German painting ; History of collections ; history of diplomacy ; thema EDItEUR::A The Arts::AG The Arts: treatments and subjects::AGA History of art ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: English
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    Global War, Global Catastrophe (2022)
    Bloomsbury Academic | Bloomsbury Academic
    Details
    Publication Date: 2024-04-02
    Description: Winner of the World War One Historical Association’s 2021 Norman B. Tomlinson, Jr. Prize Global War, Global Catastrophe presents a history of the First World War as an all-consuming industrial war that forcibly reshaped the international environment and, with it, impacted the futures of all the world’s people. Narrated chronologically, and available open access, the authors identify key themes and moments that radicalized the war’s conduct and globalized its impact, affecting neutral and belligerent societies alike. These include Germany’s invasion of Belgium and Britain’s declaration of war in 1914, the expansion of economic warfare in 1915, anti-imperial resistance, the Russian revolutions of 1917 and the United States’ entry into the war. Each chapter explains how individuals, communities, nation-states and empires experienced, considered and behaved in relationship to the conflict as it evolved into a total global war. Above all, the book argues that only by integrating the history of neutral and subject communities can we fully understand what made the First World War such a globally transformative event. This book offers an accessible and readable overview of the major trajectories of the global history of the conflict. It offers an innovative history of the First World War and an important alternative to existing belligerent-centric studies. The ebook editions of this book are available open access under a CC BY-NC-ND 3.0 licence on bloomsburycollections.com.
    Keywords: First World War ; General and world history ; thema EDItEUR::N History and Archaeology::NH History::NHB General and world history ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999 ; thema EDItEUR::N History and Archaeology::NH History::NHW Military history::NHWR Specific wars and campaigns::NHWR5 First World War ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999::3MPB Early 20th century c 1900 to c 1950::3MPBF c 1910 to c 1919::3MPBFB c 1914 to c 1918 (World War One period)
    Language: English
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    Movable Inn. The Rural Jewish Population of Minsk Guberniya in 1793-1914 (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Description: The book presents the results of a systematic survey, the first of its kind, on the rural Jews in the Minsk Guberniya, from its establishment as a major administrative unit within the Russian Empire in 1793, to the outbreak of the First World War in 1914.
    Keywords: D204-475 ; DJK1-77 ; family structure ; Jews ; demography ; culture ; landlords ; Belarus ; genealogy ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: English
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    Jugendbewegung, Antisemitismus und rechtsradikale Politik (2022)
    De Gruyter | De Gruyter Oldenbourg
    Details
    Publication Date: 2024-04-01
    Description: The year 2013 marks the centennial of the first "Free-German Youth Day" that took place on the Meissner massif. Anti-Semitic outbursts erupted at the margins of this historical gathering. In its wake, a right-wing populist faction of the youth movement arose for the first time. This collected volume examines the interface between the youth movement, nationalism, and anti-Semitism.
    Keywords: Anti-Semitism ; the youth movement ; right-wing extremism ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999 ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPF Political ideologies and movements
    Language: German
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    Assembly of the Photosystem II Membrane-Protein Complex of Oxygenic Photosynthesis (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Photosystem II is a 700-kDa membrane-protein super-complex responsible for the light-driven splitting of water in oxygenic photosynthesis. The photosystem is comprised of two 350-kDa complexes each made of 20 different polypeptides and over 80 co-factors. While there have been major advances in understanding the mature structure of this photosystem many key protein factors involved in the assembly of the complex do not appear in the holoenzyme. The mechanism for assembling this super-complex is a very active area of research with newly discovered assembly factors and subcomplexes requiring characterization. Additionally the ability to split water is inseparable from light-induced photodamage that arises from radicals and reactive O2 species generated by Photosystem II chemistry. Consequently, to sustain water splitting, a “self repair” cycle has evolved whereby damaged protein is removed and replaced so as to extend the working life of the complex. Understanding how the biogenesis and repair processes are coordinated is among several important questions that remain to be answered. Other questions include: how and when are the inorganic cofactors inserted during the assembly and repair processes and how are the subcomplexes protected from photodamage during assembly? Evidence has also been obtained for Photosystem II biogenesis centers in cyanobacteria but do these also exist in plants? Do the molecular mechanisms associated with Photosystem II assembly shed fresh light on the assembly of other major energy-transducing complexes such as Photosystem I or the cytochrome b6/f complex or indeed other respiratory complexes? The contributions to this Frontiers in Plant Science Research Topic are likely to reveal new details applicable to the assembly of a range of membrane-protein complexes, including aspects of self-assembly and solar energy conversion that may be applied to artificial photosynthetic systems. In addition, a deeper understanding of Photosystem II assembly — particularly in response to changing environmental conditions — will provide new knowledge underpinning photosynthetic yields which may contribute to improved food production and long-term food security.
    Keywords: QK1-989 ; Q1-390 ; Arabidopsis thaliana ; photoactivation ; photosynthesis ; Chlamydomonas reinhardtii ; cyanobacteria ; biogenesis ; Photosystem II ; photodamage ; Nicotiana tabacum ; Synechocystis sp. PCC 6803 ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Language: English
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    Recent Advances and Challenges on Big Data Analysis in Neuroimaging (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Big data is revolutionizing our ability to measure and study the human brain. New technology increases the resolution of images that are being study as well as enables researchers to study the brain as it functions. These technological advances are combined with efforts to collect neuroimaging data on large numbers of subjects, in some cases longitudinally. This combination of advances in measurement and scope of studies requires novel development in the statistical analysis. Fast, scalable, robust and accurate models and approaches need to be developed to make headway on these problems. This volume represents a unique collection of researchers providing deep insights on the statistical analysis of big neuroimaging data.
    Keywords: RC321-571 ; Q1-390 ; fMRI ; Neuroscience ; functional connectivity ; EEG ; Classification ; prediction ; big data ; MEG ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    The Routledge Companion to Global Renaissance Art (2024)
    Taylor & Francis | Routledge
    Details
    Publication Date: 2024-03-23
    Description: This companion examines the global Renaissance through object-based case studies of artistic production from Africa, Asia, the Americas, and Europe in the early modern period. The international group of contributors take an art historical approach characterized by close analysis of form and meaning as well as function, and a focus on questions of crosscultural dialogue and adaptation. Seeking to de-emphasize the traditional focus on Europe, this book is a critical guide to the literature and the state of the field. Chapters outline new questions and agendas while pushing beyond familiar material. Main themes include workshops, the migrations of artists, objects, technologies, diplomatic gifts, imperial ideologies, ethnicity and indigeneity, sacred spaces and image cults, as well as engaging with the open questions of "the Renaissance" and "the global." This will be a useful and important resource for researchers and students alike and will be of interest to scholars working in art history, visual culture, material culture, and Renaissance studies. The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license
    Keywords: Renaissance ; early modern ; art ; art history ; visual studies ; material culture ; objects ; Europe ; Americas ; Africa ; Asia ; Australia ; Oceania ; cross-cultural ; inter-cultural ; global ; colonialism ; colonization ; pre-modern ; geography ; exchange ; trade ; politics ; empire ; influence ; imperialism ; mobility ; cartography ; markets ; courts ; thema EDItEUR::A The Arts::AB The arts: general topics ; thema EDItEUR::A The Arts::AG The Arts: treatments and subjects::AGA History of art ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTQ Colonialism and imperialism ; thema EDItEUR::A The Arts::AF The Arts: art forms::AFK Non-graphic and electronic art forms::AFKB Sculpture ; thema EDItEUR::A The Arts::AF The Arts: art forms::AFC Paintings and painting
    Language: English
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    Phonology in the Bilingual and Bidialectal Lexicon (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-03-29
    Description: A conversation between two people can only take place if the words intended by each speaker are successfully recognized. Spoken word recognition is at the heart of language comprehension. This automatic and smooth process remains a challenge for models of spoken word recognition. Both the process of mapping the speech signal onto stored representations for words, and the format of the representation themselves are subject to debate. So far, existing research on the nature of spoken word representations has focused mainly on native speakers. The picture becomes even more complex when looking at spoken word recognition in a second language. Given that most of the world’s speakers know and use more than one language, it is crucial to reach a more precise understanding of how bilingual and multilingual individuals encode spoken words in the mental lexicon, and why spoken word recognition is more difficult in a second language than in the native language. Current models of native spoken word recognition operate under two assumptions: (i) that listeners’ perception of the incoming speech signal is optimal; and (ii) that listeners’ lexical representations are accurate. As a result, lexical representations are easily activated, and intended words are successfully recognized. However, these assumptions are compromised when applied to a later-learned second language. For a variety of reasons (e.g., phonetic/phonological, orthographic), second language users may not perceive the speech signal optimally, and they may still be refining the motor routines needed for articulation. Accordingly, their lexical representations may differ from those of native speakers, which may in turn inhibit their selection of the intended word forms. Second language users also have to solve a larger selection challenge—having words in more than one language to choose from. Thus, for second language users, the links between perception, lexical representations, orthography, and production are all but clear. Even for simultaneous bilinguals, important questions remain about the specificity and interdependence of their lexical representations and the factors influencing cross-language word activation. This Frontiers Research Topic seeks to further our understanding of the factors that determine how multilinguals recognize and encode spoken words in the mental lexicon, with a focus on the mapping between the input and lexical representations, and on the quality of lexical representations.
    Keywords: BF1-990 ; Q1-390 ; Phonological knowledge ; Second-language speech ; bilingual and bidialectal lexicon ; spoken word recognition ; lexical access ; orthographic knowledge ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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    The Pathogenetic Mechanisms at the Basis of Aortopathy Associated with Bicuspid Aortic Valve: Insights from "Omics", Models of Disease and Emergent Technologies (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-03-31
    Description: This forum of comprehensive reviews and research studies on distinct aspects of the pathophysiology of BAV aortopathy provides both the state of the art in the knowledge on this complex disease and novel insights into its causes and consequences. The present collection of focused papers also envisions and proposes new therapeutic strategies, novel biomarkers and original risk stratification criteria, for the improvement of patient management.
    Keywords: QP1-981 ; Q1-390 ; smooth muscle cells ; microRNAs ; aortic root ; endothelial cells ; aortic surgery ; bicuspid aortic valve ; 4DFlow analysis ; aortopathy ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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    Interdisciplinary Approaches to Multilingualism (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-03-29
    Description: This research topic stems from the "Interdisciplinary Approaches to Multilingualism" conference, which was hosted by the Language Research Centre at the University of Calgary. It was the first conference of its kind, which brought together the work of researchers, educators, and policy makers in the areas of first and second language acquisition from psycholinguistic and pedagogical perspectives. The goal was to provide an opportunity for participants to engage with the implications of multilingualism from a range of perspectives, including the effects of being bilingual from infancy to adulthood, the process and benefits of learning multiple languages, and the impact of multilingualism on society.
    Keywords: BF1-990 ; Q1-390 ; Developmental psycholinguistics ; second language literacy development ; Multilingualism ; psycholinguistic research methods ; Second language pedagogy ; bilingualism ; Second Language Acquisition ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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    Església i franquisme: De la col·laboració amb el franquisme al seu combat (2021)
    Publicacions Universitat Rovira i Virgili
    Details
    Publication Date: 2024-04-01
    Description: Este libro quiere aportar conocimiento y arrojar luz sobre los hechos transcurridos durante la Guerra Civil y tras los años de dictadura, en relación al papel que jugó la Iglesia en esta época histórica. Los lectores verán enseguida cómo las relaciones entre religión y Estado pasaron por diferentes vicisitudes y etapas, y que en puridad deberíamos hablar del papel que jugaron las Iglesias (en plural) o si se prefiere de los papeles (en plural) que jugó la Iglesia. En los largos cuarenta años de la dictadura, la Iglesia sufrió importantes transformaciones, al compás de las que se experimentaban en el tejido social. Los lectores las encontrarán en estas páginas y comprobarán, una vez más, que la historia no se escribe de forma lineal.
    Keywords: D204-475 ; Guerra Civil española ; franquismo ; Iglesia ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: Catalan , Spanish
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    Personalized Nutrition (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-04-05
    Description: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    Sleep Spindles: Breaking the Methodological Wall (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: In the last decade, sleep spindles have attracted steadily increasing attention. This interest is motivated by the many intriguing relationships between spindles and various diseases (e.g., schizophrenia, Parkinson, Alzheimer, autism, mental retardation), recovery processes (e.g., post brain stroke), and cognitive faculties (e.g., memory consolidation, intelligence, dream recall, sleep preservation). Nonetheless, a methodological wall has impeded the study of sleep spindles. Their investigation rests heavily on our ability to reliably and consistently identify spindle patterns from background EEG activity, a task involving many obstacles, including: a fuzzy definition of spindles, low inter-expert agreement on their scoring, lack of consensus on standard techniques for their automated detection, low reproducibility of observed characteristics and correlates, unavailability of large, standardized, high-quality databases, and inconsistencies in the methods used to evaluate the performance of automated detectors. The primary aims of this research topic were to bring together world-class researchers on a project designed to facilitate exchanges on methodological difficulties encountered in assessing sleep spindles and to promote standardized spindle-related resources. In preparing their contributions, authors were encouraged to use existing – or to propose new – publicly available resources for assessing sleep spindles. To allow fair and accurate comparison of reported results, the authors were also encouraged to validate their tools on a common benchmark. A database containing expert spindle scoring (i.e., the Montreal Archive of Sleep Studies) was made publicly available for that purpose.
    Keywords: RC321-571 ; Q1-390 ; Neural oscillations ; Electroencephalography (EEG) ; Sleep ; Sleep Spindles ; Memory ; IQ ; sigma waves ; automatic detection ; biomarker ; Open access ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Energy metabolism (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-03-31
    Description: Energy metabolism is central to life and altered energy expenditure (EE) is often cited as a central mechanism responsible for development of the obese phenotype. Resting EE, EE of physical activity, cold induced thermogenesis and thermic effect of feeding add to produce total EE but can also affect each other. It is thus very important that each component be well measured. Measuring energy expenditure by indirect calorimetry is extremely simple in theory but the practice if far more difficult. Taking into account temperature in small sized animals, measuring accurately the effect of activity on EE, correcting EE for body size body composition, age sex etc… add difficulties in producing reliable data. The goal of this Research Topic was to call for the practical experience of main investigators trained to practice calorimetry in order to get their feedback and the way they deal with the various and specific problems of humans and animal calorimetry. The goal is to share the questions/solutions experienced by the contributors to inititate a “guide of the good practices” that can be periodically updated and used by all those who are and will be interested in measuring energy metabolism from the 20g mouse to the human and large farm animals.
    Keywords: QP1-981 ; Q1-390 ; Body Composition ; Thermogenesis ; brown adipose tissue ; Body Size ; Energy Expenditure ; indirect calorimetry ; physical activity ; metabolic Phenotyping ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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    Landscapes in the Eastern Mediterranean between the Future and the Past (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2023-12-20
    Description: Landscapes have long been viewed as ‘multifunctional’, integrating ecological, economic, sociocultural, historical, and aesthetic dimensions. Landscape science and public awareness in Europe have been progressing in leaps and bounds. The challenges involved in landscape-related issues and fields, however, are multiple and refer to landscape stewardship and protection, as well as to the development of comprehensive theoretical and methodological approaches, in tandem with public sensitization and participatory governance and in coordination with appropriate top-down planning and policy instruments. Landscape-scale approaches are fundamental to the understanding of past and present cultural evolution, and are now considered to be an appropriate spatial framework for the analysis of sustainability. Methods and tools of landscape analysis and intervention have also gone a long way since their early development in Europe and the United States. Although significant progress has been made, there remain many issues which are understudied or not investigated at all—at least in a Mediterranean context. This Special Issue addresses the application of landscape theory and practice in the Eastern Mediterranean and mainly, but not exclusively, reports on the outcomes of an international conference held in Jordan, in December 2015, with the title “Landscapes of Eastern Mediterranean: Challenges, Opportunities, Prospects and Accomplishments”. The focus of this Special Issue, landscapes of the Eastern Mediterranean region, thus constitutes a timely area of research interest, not only because these landscapes have so far been understudied, but also as a rich site of strikingly variegated, long-standing multicultural human–environmental interactions. These interactions, resting on and taking shape through millennia of continuity in tradition, have been striving to adapt to technological advances, while currently juggling with manifold and multilayered socioeconomic and climate–environmental crises.
    Keywords: G1-922 ; Q1-390 ; n/a ; landscape archaeology ; Cyprus ; Landscape Character Assessment (LCA) ; Eastern Mediterranean ; Land Description Units ; stakeholders’ analysis ; UK ; local authority ; ancient sanctuaries ; East Med landscape ; Twain-born Border Lord ; Landscape Decision Support System ; mapping ; topography ; Byzantine landscape and garden art ; economy ; LCA ; classification ; churches ; Arabic-speaking ; participatory ; Landscape Risk Assessment Model ; landforms ; GIS ; planning ; typology ; Greek-speaking ; public realm ; landscape changes ; sacred space ; comparative study ; urban environment ; ideology ; political power ; Arabic landscape and garden art ; cultural sustainability ; historical maps ; religion ; rural land ; multi-functional landscapes ; Lebanon ; Mediterranean ; geographical information system ; spatial distributions ; Land Description Unit (LDU) ; political sustainability ; landscape ; landscape character assessment ; governance ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
    Language: English
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    Châteaux et maisons fortes en Lorraine centrale (2022)
    Éditions de la Maison des sciences de l’homme
    Details
    Publication Date: 2024-04-01
    Description: An exhaustive inventory of fortified residences is compared here to written evidence, figurative representations and fieldwork. It retraces the evolution of seigneurial residences of the Xth to XVth centuries. These elements are reinsered into the domaine and social context thanks to the drawing up of unpublished genealogies. In this imposing work a continual contact is maintained between past and present outlining the progress of archaeological research. Actual problems such as the protection of this threatened heritage are also evoked here.
    Keywords: Moyen Âge ; château ; habitat seigneurial ; Lorraine ; maison forte ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500
    Language: French
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    Akten zur Auswärtigen Politik der Bundesrepublik Deutschland 1974 (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Keywords: D204-475 ; DD1-905 ; JA1-92 ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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    Inventar der Offenen Befehle der Sowjetischen Militaeradministration des Landes Brandenburg (2021)
    Peter Lang International Academic Publishing Group
    Details
    Publication Date: 2024-04-01
    Description: Die Publikation ist ein Gemeinschaftsprojekt des Lehrstuhls Geschichte der Militäruniversität des Verteidigungsministeriums der Russischen Föderation (Moskau), des Zentrums für Zeitgeschichte von Bildung und Wissenschaft der Universität Hannover und des Brandenburgischen Landeshauptarchivs (Potsdam). Erstmals wird hier ein Überblick über die im Staatsarchiv der Russischen Föderation in Moskau vorhandene Offene Serie der Befehle der Sowjetischen Militäradministration des Landes Brandenburg – SMAB – gegeben. Einleitend erfolgen quellenkritische und institutionsgeschichtliche Untersuchungen zur Thematik. Den Hauptteil bildet das Inventar der von der Verwaltung der SMAB zwischen 1945 und 1949 erlassenen Offenen Befehle. Auf Interesse dürfte ebenfalls die Übersicht über die von der SMAB erlassenen «Anweisungen» stoßen.
    Keywords: Befehle ; Brandenburg ; Brandenburgisches ; Föderation ; Inventar ; Landes ; Landeshauptarchiv ; Militäradministration ; Offene ; Offenen ; Russischen ; Sowjetischen ; Staatsarchiv ; Überlieferung ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MR 21st century, c 2000 to c 2100 ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPP Public administration
    Language: German
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    Global health issues of aflatoxins in food and agriculture: Challenges and opportunities (2021)
    Frontiers Media SA
    Details
    Publication Date: 2023-12-21
    Description: Aflatoxins are a group of polyketide mycotoxins that are produced mainly by members of the genus Aspergillus. Production of these toxic secondary metabolites is closely related to fungal development (Keller et al., 2005; Jamali et al., 2012). Contamination of food, feed and agricultural commodities by aflatoxins poses enormous economic and serious health concerns because these chemicals are highly carcinogenic and can directly influence the structure of DNA. The resulting genetic defects can lead to fetal misdevelopment and miscarriages; aflatoxins are also known to suppress immune systems (Razzaghi-Abyaneh et al., 2013). In a global context, aflatoxin contamination is a constant concern between the 35N and 35S latitude where developing countries are mainly situated. With expanding boundaries of developing countries, aflatoxin contamination has become a persistent problem to those emerging areas (Shams-Ghahfarokhi et al., 2013). The continuing threat by aflatoxin contamination of food, feed and agricultural commodities to the world population has made aflatoxin research one of the most exciting and rapidly developing study areas of microbial toxins. The present research topic includes six review articles, three mini reviews and four original research articles. Contributors highlight current global health issues arising from aflatoxins and aflatoxigenic fungi and cover important aspects of aflatoxin research including contamination of crops, epidemiology, molecular biology and management strategies. Special attention is given to fungus-plant host interactions, biodiversity and biocontrol, sexual recombination in aflatoxigenic aspergilli, potential biomarkers for aflatoxin exposure in humans and safe storage programs.
    Keywords: R5-920 ; QR1-502 ; Q1-390 ; TX341-641 ; genetic diversity ; Public Health ; Aspergillus flavus ; Genomics ; MicroRNAs ; Fungus host interactions ; biological control ; aflatoxin ; agricultural crops ; bic Book Industry Communication::M Medicine
    Language: English
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    Diplomatie mit Gefühl. Vertrauen, Misstrauen und die Außenpolitik der Bundesrepublik Deutschland (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Description: Following the Second World War, Germany no longer enjoyed the trust of other nations. What did West Germany do to rebuild confidence? What was the role of trust, mistrust, and supervision during the East-West conflict as West Germany was integrated into the Western alliance, and how did they affect international relations between the two blocs? This study examines personal ties, rhetorical strategies, and institutional connections.
    Keywords: D204-475 ; JZ2-6530 ; DD1-905 ; Foreign policy East-Western conflict Germany ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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    DNA helicases: expression, functions and clinical implications (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Helicases are the proteins that bind to double- or single-stranded DNA and/or RNA chains to unwind higher order structures, usually consuming energy from the hydrolysis of ATP molecules. The biological roles of helicases are associated with a variety of DNA and/or RNA metabolisms, including DNA-replication, -repair, -recombination, RNA processing, and transcription. Dysfunctions of helicases cause various diseases, such as xeroderma pigmentosum (XP), premature aging syndrome, cancer and immunodeficiency, in humans. Moreover, recent genetic analyses revealed that mutations in helicase-encoding genes are frequently found in patients of specific diseases. Some helicases regulate cellular senescence by controlling integrity of genomes, and others play a role in neuromuscular functions presumably by modulating processing of mRNAs. However, the molecular mechanisms of how helicases are regulated in order to maintain our health are not yet fully understood. In this research topic, we will focus on the expression and functions of helicases and their encoding genes, reviewing recent research progresses that provide new insights into development of clinical and pharmaceutical treatments targeting helicases.
    Keywords: QH426-470 ; Q1-390 ; DNA Repair ; Aging ; helicases ; Telomere ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Language: English
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    Coastal Resources Economics and Ecosystem Valuation (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2023-12-20
    Description: The practical importance of economic valuation information can hardly be overstated. Coastal and marine resource policy planning and management benefit from complete information on the impact of policy decisions.
    Keywords: Q1-390 ; internet survey ; open access ; contingent valuation method ; coastal management ; tourism ; Thailand ; marine ; wetlands ; harmful algae blooms ; environmental valuation ; quota ; cyanobacteria ; estuarine and coastal ecosystems ; wealth accounting ; seawater quality ; economic analysis ; remote sensing ; ecosystem restoration ; coastal ecosystems ; random utility model ; contingent behavior ; public policy ; habitat–fishery linkages ; Barbados ; coastal ecosystem services valuation ; fishery ; mangroves ; ecosystem services valuation ; coral reefs valuation ; recreational boating ; regulated open access ; non-market value ; economic valuation ; ecosystem services ; coastal ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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    Militaer und Gesellschaft in Preußen – Quellen zur Militaersozialisation 1713–1806 (2022)
    Peter Lang International Academic Publishing Group
    Details
    Publication Date: 2024-04-01
    Description: Für Alltag, Sozialleben und Erfahrungshorizont der Menschen in der Vormoderne waren militärische Aspekte allgegenwärtig. Das gesellschaftsgeschichtlich ausgerichtete Quelleninventar für die preußische Zentrallandschaft von der Elbe bis zur Oder führt tief in diese Welt. Es stellt eine Arbeitsgrundlage für ein breites historisches Forschungsspektrum zur Verfügung. Dieser erste von drei Teilen enthält eine ausführliche Einleitung mit Benutzungshinweisen und erschließt über 6.000 Archivalien des Brandenburgischen Landeshauptarchivs aus Oberbehörden der Kurmark Brandenburg von 1713 bis 1806.
    Keywords: 1713–1806 ; Archivalien ; Bahl ; Bearbeitet ; Brandenburg ; Brandenburgisches ; Claudia ; Gesellschaft ; Hälfte ; Joafchimsthaler Gymnasium ; Kloosterhuis ; Kurmärkische Domänenkammer ; Kurmärkische Kriegskammer ; Kurmärkisches Kammergericht ; Land ; Landeshauptarchiv ; Militär ; Militärsozialisation ; Nowak ; Peter ; Preußen ; Preußische Militärgeschichte ; Pröve ; Quellen ; Ralf ; Sozialgeschichte Preußens ; Teil ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history
    Language: German
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    Wie der Krieg ins Museum kam (2022)
    transcript Verlag | transcript Verlag
    Details
    Publication Date: 2024-04-01
    Description: Der »Große Vaterländische Krieg 1941-1945« machte die Mitarbeiterinnen und Mitarbeiter der sowjetischen Museen, die ›muzejsciki‹, zu Akteuren der Erinnerung. An der Front, im Hinterland und in den besetzten Gebieten sammelten sie Relikte von Kämpfen und erlittenem Leid. Ihre zeitnahen und überraschend vielschichtigen Kriegsausstellungen fanden große Resonanz bei den Besucherinnen und Besuchern. Anne E. Hasselmann setzt den Fokus auf die Sammel-, Ausstellungs- und Vermittlungsarbeit der ›muzejsciki‹ am Übergang von Erlebnis zur Erinnerung. Damit eröffnet sie neue Einblicke in die Gesellschaft im Stalinismus und schließt eine Lücke in der Erinnerungsgeschichte des Krieges, der das Selbstverständnis der russischen Gesellschaft bis heute prägt.
    Keywords: Museum ; Sowjetunion ; Zweiter Weltkrieg ; Agency ; Erinnerung ; Russland ; Stalinismus ; Vernichtungskrieg ; Erinnerungskultur ; Geschichte des 20. Jahrhunderts ; Museumswissenschaft ; Zeitgeschichte ; Geschichtswissenschaft ; Soviet Union ; Second World War ; Memory ; Russia ; Stalinism ; Memory Culture ; History of the 20th Century ; Museology ; Contemporary History ; History ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999 ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GL Library and information sciences / Museology::GLZ Museology and heritage studies ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies
    Language: German
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    Women and Power at the French Court, 1483-1563 (2021)
    Amsterdam University Press | Pallas Publications
    Details
    Publication Date: 2024-04-01
    Description: Women and Power at the French Court, 1483—1563 explores the ways in which a range of women “ as consorts, regents, mistresses, factional power players, attendants at court, or as objects of courtly patronage “ wielded power in order to advance individual, familial, and factional agendas at the early sixteenth-century French court. Spring-boarding from the burgeoning scholarship of gender, the political, and power in early modern Europe, the collection provides a perspective from the French court, from the reigns of Charles VIII to Henri II, a time when the French court was a renowned center of culture and at which women played important roles. Crossdisciplinary in its perspectives, these essays by historians, art and literary scholars investigate the dynamic operations of gendered power in political acts, recognized status as queens and regents, ritualized behaviors such as gift-giving, educational coteries, and through social networking, literary and artistic patronage, female authorship, and epistolary strategies.
    Keywords: History ; women ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: English
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    Disease and the Hippo Pathway: Cellular and Molecular Mechanisms (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-04-05
    Description: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Keywords: QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    Feedforward and Feedback Processes in Vision (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-03-29
    Description: The visual system consists of hierarchically organized distinct anatomical areas functionally specialized for processing different aspects of a visual object (Felleman & Van Essen, 1991). These visual areas are interconnected through ascending feedforward projections, descending feedback projections, and projections from neural structures at the same hierarchical level (Lamme et al., 1998). Accumulating evidence from anatomical, functional and theoretical studies suggests that these three projections play fundamentally different roles in perception. However, their distinct functional roles in visual processing are still subject to debate (Lamme & Roelfsema, 2000). The focus of this Research Topic is the roles of feedforward and feedback projections in vision. Even though the notions of feedforward, feedback, and reentrant processing are widely accepted, it has been found difficult to distinguish their individual roles on the basis of a single criterion. We welcome empirical contributions, theoretical contributions and reviews that fit into any one (or a combination) of the following domains: 1) their functional roles for perception of specific features of a visual object 2) their contributions to the distinct modes of visual processing (e.g., pre-attentive vs. attentive, conscious vs. unconscious) 3) recent techniques/methodologies to identify distinct functional roles of feedforward and feedback projections and corresponding neural signatures. We believe that the current Research Topic will not only provide recent information about feedforward/feedback processes in vision but also contribute to the understanding fundamental principles of cortical processing in general.
    Keywords: BF1-990 ; Q1-390 ; projections ; processes ; Feedback ; Vision ; feedforward ; Visual System ; mechanisms ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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    Enklaven (2022)
    De Gruyter | De Gruyter Oldenbourg
    Details
    Publication Date: 2024-04-02
    Description: Die Bezeichnung „Enklave“ wird für unterschiedliche Phänomene und Prozesse verwendet. Enklaven sind in sozialer, politischer oder wirtschaftlicher Hinsicht von den sie umgebenden Räumen wie Nationalstaaten, Städten oder Wirtschaftssektoren abgegrenzt. Enklaven umschließen soziokulturelle Minderheiten, „Staaten im Staate“ oder Produktionszonen, die den Interessen auswärtiger Akteure oder bestimmter Interessengruppen dienen. Innerhalb von Enklaven gelten eigene Regeln. Dieser Band beleuchtet Enklavenbildung am Beispiel der Förderung von Rohstoffen in Afrika
    Keywords: Enclaves ; Raw Materials ; Africa ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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    Building Strategies for Porcine Cancer Models (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: The eBook "Building Strategies for Porcine Cancer Models" presents a series of articles demonstrating the state-of-the-art developments in pig models for cancer research. Renowned researchers dedicated to the reproduction, genomic and biological engineering of the pig model for biomedicine contribute to this special research area. Although advances in these areas are occurring at surprising speeds, they are still far from realizing all the potential benefits that this biological model could provide to science. The current biomedical models may limit the frontier of knowledge in the cancer research.
    Keywords: QH426-470 ; Q1-390 ; Pigs ; Cloning ; Genetic engineering ; Comparative Genomics ; Gene Editing ; Animal Models ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Language: English
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    Smelly Fumes: Volatile-Mediated Communication between Bacteria and Other Organisms (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: This e-book summarizes recent advances in the young and rapidly developing field of microbial volatiles. Articles included here reveal novel information about the chemical diversity of bacterial and fungal volatiles, their functions, their roles in inter-specific and inter-kingdom interactions and the metabolic and physiological changes their exposure causes in the target organisms. The e-book is divided in three chapters: (1) Natural Functions of Microbial Volatiles; (2) Volatile Production and Ecosystem Functioning and (3) Volatile Detection and Identification.
    Keywords: QR1-502 ; Q1-390 ; microorganisms ; infochemicals ; natural functions ; induced systemic resistance ; Plants ; antimicrobials ; plant growth promotion ; volatiles ; interactions ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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    Deutsche und polnische Juden vor dem Holocaust. Jüdische Identität zwischen Staatsbürgerschaft und Ethnizität 1933-1940 (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Keywords: D204-475 ; DD1-905 ; JA1-92 ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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    Agroforestry Systems: The Role of Trees in Ecosystem Services—A Special Issue in Collaboration with the 4th World Congress on Agroforestry (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-04-05
    Description: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    Handwerk und Kleinhandel in der Bundesrepublik Deutschland. Sozialökonomischer Wandel und Mittelstandspolitik 1949–1961 (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Keywords: D204-475 ; DD1-905 ; JA1-92 ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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    Conceptual Categories and the Structure of Reality: Theoretical and Empirical Approaches (2021)
    Frontiers Media SA
    Details
    Publication Date: 2023-12-20
    Description: In this eBook, Conceptual Categories and the Structure of Reality, the title very well describes the book's content. Within the book's pages a selection of academics from a variety of human behaviour, human/social science and humanities disciplines write about their research all of which can be typified by their consideration of how categories are used to structure understanding of phenomena. These authors have considered how reality may be understood through notions such as categorial and structural ontologies, part-whole relatoinships (mereology), the qualitative, quantitative and philosophical use of the facet theory approach to research, mapping sentences and declarative mapping sentence, hermeneutics, concepts and constructs, similarities and differences. The resulting collection presents the foregoing conceptual and empirical approaches to knowledge development in general (chapter 1&3 Hackett); Phillips and Wislons' review of compositional syntax in bird calls (chapter 2); neurobehavioral decision systems (chapter 4 Foxall); representations of human psychological processes (chapter 5 Juan-Miguel López-Gil; Rosa Gil; Roberto García); free associations mirroring and its relation to self- and world-related concepts (chapter 6 Martin Kuška; Radek Trnka; Aleš Antonín Kuběna; Jiří Růžička); local knowledge and going beyond the data (chapter 7 Steven Phillips); categorical etiologies of speech sound disorders (chapter 8 Kelly Farquharson); similarity of visual appearance (chapter 9 Nao Nakatsuji; Hisayasu Ihara; Takeharu Seno; Hiroshi Ito); and a consideration of the seminal writing of David Oderberg's on the categorial classification of reality (chapter 10 Hackett).
    Keywords: BF1-990 ; Q1-390 ; mereology ; similarities ; hermeneutics ; concepts ; category ; ontology ; facet theory ; declarative mapping sentence ; bic Book Industry Communication::J Society & social sciences::JM Psychology
    Language: English
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    Catálogo dos estágios iniciais de desenvolvimento dos peixes da bacia de Campos (2021)
    SciELO Books - Sociedade Brasileira de Zoologia
    Details
    Publication Date: 2023-12-20
    Description: Foram identificados 4.490 indivíduos incluindo 17 ordens, 68 famílias e 160 espécies de peixes nos estágios de larvas e juvenis. Foram elaborados textos com informações gerais das ordens e famílias, descrição das principais características das espécies, fotografias dos diferentes estágios de desenvolvimento, georeferrenciamento, habitat da espécie, nome vulgar e as referências utilizadas para a identificação.
    Keywords: Q1-390 ; SCIENCE ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: Portuguese
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    Racism in Modern Russia (2022)
    Bloomsbury Academic | Bloomsbury Academic
    Details
    Publication Date: 2024-04-02
    Description: In October 2013, one of the largest anti-migrant riots took place in Moscow. Clashes and arrests continued late into the night. Some in the crowd, which grew to several thousand people, could be heard chanting “Russia for the Russians” with their animus directed towards dark-skinned labor migrants from the southern border. The slogan “Russia for the Russians” is not a recent invention. It first gained notoriety in the very last years of the tsarist regime, appealing primarily to individuals drawn to the radical right. Analyzing a wide range of printed and visual sources, Racism in Modern Russia marks the first serious attempt to understand the history of racism over a span of 150 years. A brilliant examination of the complexities of racism, Eugene M. Avrutin’s panoramic book asks powerful questions about inequality and privilege, denigration and belonging, power and policy, and the complex historical links between race, whiteness, and geography. The ebook editions of this book are available open access under a CC BY-NC-ND 4.0 license on www.bloomsburycollections.com.
    Keywords: Society ; culture ; racial studies ; race ; prejudice ; hate crimes ; modern history ; Russian history ; social history ; discrimination ; anti-racism ; anti-racist ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999 ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MR 21st century, c 2000 to c 2100
    Language: English
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    Meine Vertreibung aus Prag. Erinnerungen an den Prager Aufstand 1945 und seine Folgen (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Keywords: D204-475 ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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    Die Kreuzfahrerstaaten als multikulturelle Gesellschaft. Einwanderer und Minderheiten im 12. und 13. Jahrhundert (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Description: Das international besetzte Kolloquium vom September 1994 widmete sicheinem zuvor vernachlässigten Thema. Es ist eine wesentliche Erkenntnisdes Kolloquiums, daß die Einwanderung - die hier untersucht wird fürden Adel, die Kirche, die Zentralverwaltung, die Wirtschaft und dieKunst - die Kreuzfahrerstaaten vor intellektueller und kulturellerVersteinerung bewahrte und sie auf der Höhe der europäischenEntwicklung hielt. Bei den Minderheiten zeigen mehrere Beiträge dieSchwierigkeiten im Zusammenleben mit den lateinischen Eroberern, mitdenen man trotz aller Abneigung zu fragilen Symbiosen kommen mußte.
    Keywords: D111-203 ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500
    Language: English , French , German
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    Deutsche in Polen nach 1945. Gefangene und Fremde (2021)
    De Gruyter
    Details
    Publication Date: 2024-04-01
    Keywords: D204-475 ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day
    Language: German
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    Chapter 4 Quarantine in Ceuta and Malta in the travel writings of the late-eighteenth-century Moroccan ambassador Ibn Uthmân Al-Meknassî (2021)
    Manchester University Press | Mediterranean quarantines, 1750–1914: Space, identity and power
    Details
    Publication Date: 2024-04-02
    Description: This chapter examines the writings of the renowned late-eighteenth-century Moroccan ambassador Ibn Uthmân Al-Meknassî, the first known traveller from his country to leave an account of European quarantine as experienced during his two diplomatic missions in Spain’s Ceuta (1779) and Malta’s Valletta (1782). It shows that quarantine, on the one hand, acted as a marker of otherness by which Ibn Othman was identified as a Muslim, though this was not a uniform process, owing to the fact that significant differences existed in the degree of alterity experienced in Spain and Malta, and indeed other parts of the Mediterranean. The subjective opinion on quarantine, on the other hand, was also one of the means through which Ibn Uthmân situated himself within Makhzen (Moroccan government) elites at a time when a division between those who declared themselves in favour of European-style modernisation and those who advocated a rejection of European novelties was already visible.
    Keywords: ibn uthmân al-meknassî ; spain ; diplomatic missions ; morocco ; 18th century ; quarantine ; malta ; muslim identity ; ibn uthmân al-meknassî ; spain ; diplomatic missions ; morocco ; 18th century ; quarantine ; malta ; muslim identity ; Ceuta ; Epidemic ; Mediterranean Sea ; Tangier ; Travel literature ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history ; thema EDItEUR::J Society and Social Sciences ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine
    Language: English
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    Applied Olfactory Cognition (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-03-29
    Description: Foreword by Richard J. Stevenson, Macquarie University (Australia): It was long thought that the human nose might be able to discriminate somewhere in the order of 10,000 different odourants. The recent finding that the human nose can discriminate something like a trillion different smells serves as yet another reminder that we have again underestimated the capacity of our sense of smell (Bushdid, Magnasco, Vosshall & Keller, 2014). This volume serves as a further corrective for anyone who should hold the view that olfaction is unimportant in human affairs. The papers presented in this ebook, carefully collated and overseen by Aldo Zucco, Benoist Schaal, Mats Olsson and Ilona Croy, showcase a large number of quite different reasons for studying the applied side of olfaction, and indeed human olfaction in general. The 23 contributions presented here cover a broad range of topics, which illustrate contemporary interests in our field. Although with a strong applied focus, a noteworthy feature of this ebook is the richness of the theoretical perspectives that are developed. These range from considerations of olfactory perception, memory, expertise, and priming right the way through to receptor genetics. These contributions, from many leading experts in the field, will surely shape much of the applied work linking olfaction to disease, which is a further focus of this ebook. In respect to health and disease, the chapters on aging, pregnancy, depression, alcohol dependency and environmental odours, present overviews and rich new data on many contemporary problems, to which the study of olfaction is now contributing. A particularly notable aspect of olfactory experience is the affective impact that odours can have on people and their lives. The ebook covers some particularly intriguing aspects of work in this area, with empirical studies investigating dissociations between wanting and liking, stress reduction in the elderly, mother-infant bonding, and the emotions that different odourants can evoke. This affective line of work is nicely complemented by empirical studies on expertise, the effect of odours on visual attention, and the relationship between particular personality traits and interest in olfaction. The gradual appropriation of methods from cognitive neuroscience into olfaction is also nicely represented in this ebook, with at least three of the chapters reporting data using neuroimaging, including a particular intriguing study looking at recognition of odours in mixtures. Finally, the close links between olfactory perception and sensory evaluation are also reflected in a chapter on wine. I hope that readers of this e-book will be struck, as I have been in reading its various chapters, how much olfaction affects our lives, and how the study of this sense can enrich it.
    Keywords: BF1-990 ; Q1-390 ; Disease ; Health ; Everyday Life ; Cognition ; Applied olfaction ; Expertise ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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    Advances in Airborne Lidar Systems and Data Processing (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2022-01-31
    Description: This edition is a reprint of the Special Issue published online in the open access journal Remote Sensing (ISSN 2072-4292) from 2016–2017 (available at: http://www.mdpi.com/journal/remotesensing/special issues/rsALS), complemented by selected articles published in Remote Sensing
    Keywords: G1-922 ; Q1-390 ; Airborne Lidar Systems ; Data Processing
    Language: English
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    Genetics and epigenetics of fetal alcohol spectrum disorders (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: Women drinking during pregnancy can result in Fetal Alcohol Spectrum Disorder (FASD), which may feature variable neurodevelopmental deficits, facial dysmorphology, growth retardation, and learning disabilities. Research suggests the human brain is precisely formed through an intrinsic, genetic-cellular expression that is carefully orchestrated by an epigenetic program. This program can be influenced by environmental inputs such as alcohol. Current research suggests the genetic and epigenetic elements of FASD are heavily intertwined and highly dependent on one another. As such, now is the time for investigators to combine genetic, genomic and epigenetic components of alcohol research into a centralized, accessible platform for discussion. Genetic analyses inform gene sets which may be vulnerable to alcohol exposure during early neurulation. Prenatal alcohol exposure indeed alters expression of gene subsets, including genes involved in neural specification, hematopoiesis, methylation, chromatin remodeling, histone variants, eye and heart development. Recently, quantitative genomic mapping has revealed loci (QTLs) that mediate alcohol-induced phenotypes identified between two alcohol-drinking mouse strains. One question to consider is (besides the role of dose and stage of alcohol exposure) why only 5% of drinking women deliver newborns diagnosed with FAS (Fetal Alcohol Syndrome)? Studies are ongoing to answer this question by characterizing genome-wide expression, allele-specific expression (ASE), gene polymorphisms (SNPs) and maternal genetic factors that influence alcohol vulnerability. Alcohol exposure during pregnancy, which can lead to FASD, has been used as a model to resolve the epigenetic pathway between environment and phenotype. Epigenetic mechanisms modify genetic outputs through alteration of 3D chromatin structure and accessibility of transcriptional machinery. Several laboratories have reported altered epigenetics, including DNA methylation and histone modification, in multiple models of FASD. During development DNA methylation is dynamic yet orchestrated in a precise spatiotemporal manner during neurulation and coincidental with neural differentiation. Alcohol can directly influence epigenetics through alterations of the methionine pathway and subsequent DNA or histone methylation/acetylation. Alcohol also alters noncoding RNA including miRNA and transposable elements (TEs). Evidence suggests that miRNA expression may mediate ethanol teratology, and TEs may be affected by alcohol through the alteration of DNA methylation at its regulatory region. In this manner, the epigenetic and genetic components of FASD are revealing themselves to be mechanistically intertwined. Can alcohol-induced epigenomic alterations be passed across generations? Early epidemiological studies have revealed infants with FASD-like features in the absence of maternal alcohol, where the fathers were alcoholics. Novel mechanisms for alcohol-induced phenotypes include altered sperm DNA methylation, hypomethylated paternal allele and heritable epimutations. These studies predict the heritability of alcohol-induced epigenetic abnormalities and gene functionality across generations. We opened a forum to researchers and investigators the field of FASD to discuss their insights, hypotheses, fresh data, past research, and future research themes embedded in this rising field of the genetics and epigenetics of FASD. This eBook is a product of the collective sharing and debate among researchers who have contributed or reviewed each subject.
    Keywords: QH426-470 ; QH301-705.5 ; Q1-390 ; DNA Methylation ; Fetal Alcohol Syndrome ; histone modification ; Epigenetic medicine ; Genomics ; Alcoholism ; transgenerational ; Pregnancy drinking ; FASD ; Gene environmental interaction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Language: English
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    Adaptive Function and Brain Evolution (2021)
    Frontiers Media SA
    Details
    Publication Date: 2024-04-05
    Description: The brain of each animal shows specific traits that reflect its phylogenetic history and its particular lifestyle. Therefore, comparing brains is not just a mere intellectual exercise, but it helps understanding how the brain allows adaptive behavioural strategies to face an ever-changing world and how this complex organ has evolved during phylogeny, giving rise to complex mental processes in humans and other animals. These questions attracted scientists since the times of Santiago Ramon y Cajal one of the founders of comparative neurobiology. In the last decade, this discipline has undergone a true revolution due to the analysis of expression patterns of morphogenetic genes in embryos of different animals. The papers of this e-book are good examples of modern comparative neurobiology, which mainly focuses on the following four Grand Questions: a) How are different brains built during ontogeny? b) What is the anatomical organization of mature brains and how can they be compared? c) How do brains work to accomplish their function of ensuring survival and, ultimately, reproductive success? d) How have brains evolved during phylogeny? The title of this e-book, Adaptive Function and Brain Evolution, stresses the importance of comparative studies to understand brain function and, the reverse, of considering brain function to properly understand brain evolution. These issues should be taken into account when using animals in the research of mental function and dysfunction, and are fundamental to understand the origins of the human mind.
    Keywords: RC321-571 ; Q1-390 ; comparative neurobiology ; brain evolution ; phylogeny ; ontogeny ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    An Equal Burden (2021)
    Oxford University Press
    Details
    Publication Date: 2024-04-01
    Description: "An Equal Burden forms the first scholarly study of the Army Medical Services in the First World War to focus on the roles and experiences of the men of the ranks of the Royal Army Medical Corps (RAMC). These men, through their work as stretcher bearers and orderlies, provided a range of labour, both physical and emotional, in aid of the sick and wounded. They were not professional medical caregivers, yet were called upon to provide medical care, however rudimentary; they served in uniform, under military discipline, yet were forbidden, as non-combatants, from carrying weapons. Their service as men in wartime, was thus unique. Structured both chronologically and thematically, this study examines both the work that RAMC rankers undertook and its importance to the running of the chain of medical evacuation. It additionally explores the gendered status of these men within the medical, military and cultural hierarchies of a society engaged in total war, locating their service within the context of that of doctors, female nurses and combatant servicemen. Through close readings of official documents, personal papers, and cultural representations, both verbal and visual, it argues that the ranks of the RAMC formed a space in which non-commissioned servicemen, through their many roles, defined and redefined medical caregiving as men’s work in wartime."
    Keywords: Royal Army Medical Corps ; First World War ; masculinity ; non-combatants ; military medicine ; care giving ; gender history ; cultural representation ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999 ; thema EDItEUR::N History and Archaeology::NH History::NHW Military history::NHWR Specific wars and campaigns::NHWR5 First World War ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MP 20th century, c 1900 to c 1999::3MPB Early 20th century c 1900 to c 1950::3MPBF c 1910 to c 1919::3MPBFB c 1914 to c 1918 (World War One period) ; thema EDItEUR::M Medicine and Nursing
    Language: English
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    Earth Observation Data Cubes (2021)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2023-12-20
    Description: Satellite Earth observation (EO) data have already exceeded the petabyte scale and are increasingly freely and openly available from different data providers. This poses a number of issues in terms of volume (e.g., data volumes have increased 10
    Keywords: G1-922 ; Q1-390 ; knowledge base ; metadata ; Synthetic Aperture Radar ; versioning ; web services ; web application ; sustainable development goals ; earth observations ; FAIR principles ; land cover classification ; semantic enrichment ; satellite imagery ; imagery ; analysis ; information extraction ; ARD ; analysis ready data ; swiss DC ; data cube ; Open Data Cube ; UN 2030 Agenda for Sustainable Development ; time-series ; graph data ; Digital Earth Australia ; query store ; open data cube ; pyroSAR ; R ; earth oberservation ; image cube ; sentinel ; open science ; Sentinel ; reproducibility ; change ; big EO data ; earth observation ; big Earth data ; Earth Observations ; Australia ; geospatial standards ; big earth data ; visualization ; UN System of Environmental Economic Accounting ; interferometric coherence ; dynamic data citation ; intelligent semantic agents ; data curation ; snow cover ; big data ; Analysis Ready Data ; climate change ; topology based map algebra ; data provenance ; Sentinel-1 ; Sentinel-2 ; remote sensing ; interoperability ; image data cube ; optical remote sensing ; dual-polarimetric decomposition ; GIS ; Gran Paradiso National Park ; data sharing ; SAR ; map algebra ; Earth observation ; Armenian DC ; data cubes ; Data Cube ; data discovery ; Earth observation data ; persistent identifier ; Landsat ; GRASS GIS ; subset ; landsat ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
    Language: English
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