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  • Oxford University Press  (23,294)
  • National Academy of Sciences  (10,184)
  • Nature Publishing Company
  • 1985-1989  (35,237)
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Keywords
Publisher
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Patent Fights Generating Late Summer Heat (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 849-851 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Some suing, one settling. The hottest item this month is the start of the long-awaited trial between Amgen (Thousand Oaks, CA) and Genetics Institute (Cambridge, MA) over patent rights to erythropoietin (EPO). While the parties may indeed be negotiating a settlement behind the scenes (presumably a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0989-849
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  • 2
    Electronic Resource
    Electronic Resource
    Role for Public Interest Groups Discussed (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 860-860 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] OXFORD, U.K.—As the U.K. government prepares to publish legislative proposals concerning the release of genetically engineered organisms into the environment, it is facing calls from prominent biotechnologists for public interest groups to be actively involved in the regulatory process. The ...
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    URL: http://dx.doi.org/10.1038/nbt0989-860
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  • 3
    Electronic Resource
    Electronic Resource
    Of Bioprogramming, and a New Program (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 654-654 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Neutering agents (successful in early animal trials), a possible synthetic peptide-based vaccine for acquired immunodeficiency syndrome, a new polymer anti-skid runway coating, and a compound for treating prostate cancer, are four patented developments to emerge thus far from the ...
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    URL: http://dx.doi.org/10.1038/nbt0789-654
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  • 4
    Electronic Resource
    Electronic Resource
    World Bank to Help Weave a ‘Seamless Web’ (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 856-857 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—The role of multilateral agencies such as The World Bank (The Bank, Washington, DC) in stimulating Third World agricultural development is well documented. The Green Revolution, which permitted food production to keep pace with population growth in the 1960s, was in large measure a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0989-856
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  • 5
    Electronic Resource
    Electronic Resource
    Comparing the Efficacy of CSFs in Therapy (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 859-859 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] ORLANDO, Fla.—These are still the early days of immunotherapy, but clinicians and researchers alike respect the fact that they are playing with a new set of rules—even if they don't know what they all are yet. Still, some of the differences between chemotherapy and immunotherapy are ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0989-859
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  • 6
    Electronic Resource
    Electronic Resource
    Fish Drift Between Agencies' Guidelines (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 865-865 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Last March the Agricultural Biotechnology Research Advisory Committee (ABRAC) of the U.S. Department of Agriculture (USDA) reviewed a proposal from researchers at Auburn University (Auburn, AL) to test genetically engineered carp in outdoor ponds (Bio/Technology 7: 424, May ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0989-865
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  • 7
    Electronic Resource
    Electronic Resource
    Safe Process-Scale Chromatographs: Standards and Options (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 721-721 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Recent advances in high-performance liquid chromato-graphic column design, packings, and automation have made the technique indispensable for purifying pharmaceuticals. But moving liquid chromatography (LC) to an industrial setting brings new issues. Safety, both for the plant personnel and the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0789-721
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  • 8
    Electronic Resource
    Electronic Resource
    New Products (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 960-964 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Retinoblastoma Antibody PharMingen (San Diego, CA) will make available monoclonal antibodies specific for the human retinoblastoma (RB) gene product, a protein thought to be important in cancer suppression and cell growth regulation. These antibodies immunoprecipitate authentic RB proteins, are ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0989-960
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  • 9
    Electronic Resource
    Electronic Resource
    Observations on the Development of Biotechnology Centers: The Birth of the CBC (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 684-685 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The first centers devoted to local, regional, or statewide development of biotechnology were started in North Carolina and Michigan only eight years ago. Subsequently more than 50 of these centers in more than 30 states have emerged as clear catalysts in the advancement of biotechnology in the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0789-684
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  • 10
    Electronic Resource
    Electronic Resource
    High-Level Expression and In Vivo Processing of Chimeric Ubiquitin Fusion Proteins in Saccharomyces Cerevisiae (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 705-709 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have developed a system for the regulatable production of high levels of correctly processed heterologous proteins in the yeast Saccharomyces cerevisiae. An expression vector, pBS24Ub, that contains a synthetic gene for yeast ubiquitin (Ub) was constructed. The gene was expressed under the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0789-705
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  • 11
    Electronic Resource
    Electronic Resource
    Corn: From Protoplasts to Fertile Plants (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 548-548 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Plant biotechnologists have taken another important step towards the genetic engineering of maize. Two papers in this issue of Bio/Technology report the regeneration of fertile corn plants from protoplasts. Although our group had previously demonstrated the regeneration of mature plants from the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0689-548
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  • 12
    Electronic Resource
    Electronic Resource
    Of EPA, Risks, and Rule Making (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 555-555 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—The specter of biotechnology gone amok continues to haunt the Environmental Protection Agency (EPA). Charged under the Toxic Substances Control Act (TSCA) with regulating the commercial use of microorganisms, the agency does not want to risk public disapproval by appearing to ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0689-555
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  • 13
    Electronic Resource
    Electronic Resource
    Wistar Frustrated Over Rabies Test Plans (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 541-543 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Researchers at the Wistar Institute (Philadelphia, PA) are feeling frustrated in their efforts to field test a genetically engineered rabies vaccine. Officials at the U.S. Department of Agriculture (USDA) Animal and Plant Health Inspection Service (APHIS) concluded in a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0689-541
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  • 14
    Electronic Resource
    Electronic Resource
    A Prospectus for Multispectral-Multiplex DNA Sequencing (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 576-580 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] First-generation automated DNA sequencers are based on operations, manipulations, and methodologies not unlike those performed by their human predecessors. While these instruments may reduce labor, they do not increase sequencing rates by exponential factors. Here we review several new ...
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    URL: http://dx.doi.org/10.1038/nbt0689-576
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  • 15
    Electronic Resource
    Electronic Resource
    Announcements (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 387-387 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] APRIL MEETINGS Apr. 17–22. 2nd Cuban and International Seminar on Biotechnology. Havana, Cuba. Info: Interferón y Biotecnología '89, Apartado Postal 6162, La Habana, Cuba. Apr. 24–25. Cancer Progress IV. New York, NY. Info: Communitech Market Intelligence. P.O. Box 67, ...
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    URL: http://dx.doi.org/10.1038/nbt0489-387
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  • 16
    Electronic Resource
    Electronic Resource
    And Software Too (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 386-386 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: In the article by Mark Ratner, “Dynamic Market Emerging for Molecular Modeling”(Bio/Technology 7: 43, Jan. '89), you did not mention BioDesign, another leading supplier of molecular modeling software packages. Our two major products, Biograf™ and Polygraf™, ...
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    URL: http://dx.doi.org/10.1038/nbt0489-386d
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  • 17
    Electronic Resource
    Electronic Resource
    Regeneration of Fertile Plants from Protoplasts of Elite Inbread Maize. (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 581-587 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have obtained friable, non-mucilaginous embryogenic callus from cultured immature embryos of an elite maize inbred line derived from Iowa stiff stalk synthetic germplasm. This callus was used to generate embryogenic cell suspensions containing compact clumps of densely cytoplasmic cells. Plants ...
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    URL: http://dx.doi.org/10.1038/nbt0689-581
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  • 18
    Electronic Resource
    Electronic Resource
    Amplifying Probe Assays with Q-Beta Replicase (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 609-610 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] DNA and RNA probe assays—for genetic analyses, clinical diagnostics, and food safety testing—are powerful tools for determining the presence of specific nucleic acid sequences. Amplification methods that increase the amount of DNA or RNA available for detection add speed and sensitivity ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0689-609
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  • 19
    Electronic Resource
    Electronic Resource
    A Ray of Hope for Animal Patents in Europe (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 221-221 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] ITHACA, N.Y.—One topic generating much discussion at the Cornell University Animal Patent Symposium, held here in December, was inventors' frustrations at their inability to patent higher plants and animals in Europe. Although most of the symposium dealt with U.S. patent issues and their ...
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    URL: http://dx.doi.org/10.1038/nbt0389-221
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  • 20
    Electronic Resource
    Electronic Resource
    European Restraints Tie Up U.S. Beef Exports (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 111-113 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Deadlocked over the issue of beef treated with growth promoters, the European Community (EC) and the U.S. are resorting to retaliatory restrictions in what threatens to escalate into an all-out trade war. On January 1, the EC, citing health concerns, began acting on a decision it ...
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    URL: http://dx.doi.org/10.1038/nbt0289-111
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  • 21
    Electronic Resource
    Electronic Resource
    Biotech in Full Bloom at Coast Conference (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 119-119 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SAN FRANCISCO—A mixture of pragmatism and optimism imbued the Hambrecht & Quist Seventh Annual Health Care Conference held here January 9–11. Among the 140 presenting companies numbered 40 biotechnology companies and two major pharmaceutical firms—Glaxo (London) and Squibb ...
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    URL: http://dx.doi.org/10.1038/nbt0289-119
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  • 22
    Electronic Resource
    Electronic Resource
    Success in Engineering E. Coli Secretion (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 209-209 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A bicomponent system for secreting foreign proteins from E. coli. One plasmid expresses bacteriocin release protein (BRP) that renders the outer membrane permeable. The other encodes the synthesis of human growth hormone (hGH) fused to a signal peptide (OmpA), allowing the hormone to enter the ...
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    URL: http://dx.doi.org/10.1038/nbt0389-209
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  • 23
    Electronic Resource
    Electronic Resource
    Biotech: Experimental Subject (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 216-216 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Two Cornell University (Ithaca, NY) professors are attempting to determine the most effective ways to finance and manage the transfer of basic biotechnology research to the marketplace. In a study expected to take three to five years, John Freeman of the Johnson School of Management ...
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    URL: http://dx.doi.org/10.1038/nbt0389-216
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  • 24
    Electronic Resource
    Electronic Resource
    Solving Scale–Up: Radial Flow Chromatography (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 250-255 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] FIGURE 1. RADIAL FLOW CHROMATOGRAPHY. INSTEAD OF FLOWING DOWN THE LENGTH OF THE COLUMN, AS IN CONVENTIONAL CHROMATOGRAPHY, SAMPLES TO BE PURIFIED FLOW ACROSS THE COLUMN, FROM THE OUTER TO THE INNER COMPARTMENT. Chromatography-based purification is emerging as a critical unit operation in ...
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    URL: http://dx.doi.org/10.1038/nbt0389-250
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  • 25
    Electronic Resource
    Electronic Resource
    Efficient Degradation of Trichloroethylene by a Recombinant Escherichia Coli (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 282-285 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have identified a strain of Pseudomonas mendocina that oxidizes trichloroethylene (TCE) after growth in the presence of toluene. A DNA fragment from this organism, when introduced into the appropriate expression vector system, conferred upon Escherichia coli the ability to oxidize both toluene ...
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    URL: http://dx.doi.org/10.1038/nbt0389-282
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  • 26
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    Electronic Resource
    Patents and Secondary Considerations (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 312-312 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A basic fact of free enterprise is this: unless someone has a chance to make a profit by developing a new product, then no one will make the investments necessary to bring that product to the marketplace. A second basic fact is equally obvious: unless a product is manufactured and sold, it cannot ...
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  • 27
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    Electronic Resource
    More Than Meats the Eye (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 103-103 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Back when life was, if not simpler, complex in different ways, we read not Nature and Yachting but Scientific American and Boys' Life, and took as our guide in all things temporal and spiritual a burro named Pedro. It is hard to confess these things, harder still to admit to the bits of boyhood ...
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  • 28
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    Electronic Resource
    Genentech: Don't Sell the Company Short (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 114-114 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SAN FRANCISCO—The tissue plasminogen activator (t-PA) saga has been the Genentech (So. San Francisco, CA) story over the past year. There is more, however, to Genentech's business development strategy. Two announcements made here in January—the planned development and distribution of ...
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  • 29
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    Common Denominators of Promoter Control in Pseudomonas and Other Bacteria (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1249-1254 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The analysis of gene regulation in bacteria is entering a new phase. Global regulatory networks, signal processing, responses of complexly regulated sets of genes, and interactions between regulatory systems are becoming a focus of intensive research efforts. Our understanding of how bacteria ...
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    URL: http://dx.doi.org/10.1038/nbt1289-1249
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  • 30
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    Microenvironment: The Key to Improved Cell Culture Products (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 143-145 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biopharmaceutical manufacturing using mammalian cell cultures demands attention not only to the amount of protein secreted, but also to the quality of this protein. By optimizing the cellular microenvironment, one can increase cell-specific productivity, influence protein glycosylation, and limit ...
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    URL: http://dx.doi.org/10.1038/nbt0289-143
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  • 31
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    Free Literature (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 301-301 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Titration in Progress, a 16-page color pamphlet from Radiometer Analytical A/S (Bagsvaerd, Denmark), provides a survey of systems, including titration for water analysis, COD determinations, and pH control. The brochure, outlining selection criteria, is available in both English and German. Write ...
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  • 32
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    Company Pacts Signal Commercial Progress (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 107-108 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Hambrecht & Quist (H & Q, San Francisco, CA) Seventh Annual Healthcare Conference provided the forum for a slew of corporate announcements. Among them, Cetus (Emeryville, CA) and Hoffmann-La Roche (Roche, Nutley, NJ) will collaborate on the development and commercialization of human ...
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  • 33
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    Implantable Glucose Sensor Expected Soon (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 116-116 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] GöHREN, G.D.R.—For patients afflicted with insulin-dependent diabetes mellitus (IDDM), controlling blood glucose at near-normal levels can best reduce the disease's long-term, life-threatening cardiovascular side effects. An implantable glucose sensor would greatly aid in controlling ...
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  • 34
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    Human Disease Genes Elude Identification (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 120-120 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TORONTO, Ont.—“On Chorea,” the only scientific treatise by Long Island, NY physician George Huntington, is over a century old. Yet, despite decades of concentrated effort by scores of research scientists, the gene that causes Huntington's disease remains unidentified. So, too, for ...
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    Somatic Embryogenesis and Plant Regeneration in Suspension Cultures of Dessert (AA and AAA) and Cooking (ABB) Bananas ( Musa spp.) (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 154-159 
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    Notes: [Auszug] Proembryogenic calli were initiated from basal leaf sheaths and rhizome tissue on modified Schenk and Hildebrandt (SH) medium with 30 μM 3,6–dichloro–2–meth–oxybenzoic acid (Dicamba). Cell suspensions were maintained in half–strength Murashige and Skoog (MS) medium ...
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    Different Approaches to Stabilize a Recombinant Fusion Protein (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 165-168 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We have used a fusion protein between staphylococcal protein A and E. coli β–galactosidase as a model system to investigate different approaches to stabilize recombinant gene products. First, growth conditions were adapted to preferentially produce insoluble inclusion bodies. This ...
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    New Products (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 179-182 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Many of this month's new products will be on display at the Miami Bio/Technology Winter Symposium, February 6–10. For a closer look, visit the manufacturers at their booths. Preparative HPLC packings. Bakerbond™ wide-pore bulk packings (15-micron diameter) from J. T. Baker ...
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    Immunex Turns a Triple Play (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1115-1117 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—A series of bold strategic moves announced in September by Immunex (Seattle, WA) has left analysts buzzing and the company's stock price inching higher. By reacquiring proprietary rights it previously had traded away to its partners—in particular North American marketing rights ...
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    Environmental Research Gets a Boost (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1223-1223 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—Research into the fate of pollutants in the environment and their effects on ecosystems, and developing biotechnologies to remove toxic chemicals from effluents and waterways, are among the principal objectives of the new European Environmental Research Organization (EERO). Established ...
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    New FDA Biotech Office (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1228-1228 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] WASHINGTON, D.C.—The U.S. Food and Drug Administration (FDA, Bethesda, MD) recently established a new Office of Biotechnology within the Office of the Commissioner, to be headed by Henry Miller, formerly a special assistant to FDA Commissioner Frank Young. Miller, who has been an aggressive ...
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    Enzymes in the Fine Chemicals Industry: Dreams and Realities (1989)
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    Nature biotechnology 7 (1989), S. 1238-1241 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Although there's been considerable interest in using biocatalysts to produce fine organic chemicals, they are still made mainly by classic synthetic routes. Even after 20 years, biocatalysts haven't come into their own as major production tools in this area: nor will they—the markets just ...
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    Big vs. Little (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1248-1248 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: You seem to concentrate on the spectacular success stories of transference like Genentech, some of the firms along Route 128 in Boston, or the California companies. How about talking about some of the losers…the little guys who tried it with little or no money and almost made ...
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    Panel Considers Broadening Its Mandate (1989)
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    Nature biotechnology 7 (1989), S. 1120-1120 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] WASHINGTON, D.C.—During its October meeting, the Recombinant DNA Advisory Committee (NIH-RAC) of the National Institutes of Health (NIH, Bethesda, MD) tentatively recommended changing an essential definition that determines the scope of the committee's activities. The change would ...
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    A Perilous Path to Privatization? (1989)
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    Nature biotechnology 7 (1989), S. 846-846 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Exactly a decade ago, Britain's Microbiological Research Establishment (MRE), based at Porton Down near Salisbury, became thoroughly civilized. A Ministry of Defence station until that time, charged with maintaining a defensive capability against attack by biological weapons, MRE was transferred to ...
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    NIH Invention Development Program Advances (1989)
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    Nature biotechnology 7 (1989), S. 866-866 
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    Notes: [Auszug] WASHINGTON, D.C.—With some 5,000 researchers at its disposal, the National Institutes of Health (NIH, Bethesda, MD) churns out a great deal of biomedical know-how—much of it with commercial potential. To realize this potential more fully, NIH and other Public Health Service (PHS) ...
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    Synergen Suddenly a Hit with Investors (1989)
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    Nature biotechnology 7 (1989), S. 873-873 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] NEW YORK—Not too long ago, Synergen (Boulder, CO) was thought to be a company about to run into trouble. As recently as the beginning of this year, rumors were flying that it was being shopped around. A series of agreements with major collaborators, announced over the past few months, and the ...
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    The Reality of Capillary Electrophoresis (1989)
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    Nature biotechnology 7 (1989), S. 903-911 
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    Notes: [Auszug] Let's face it, life is wet,” says Richard Zare of Stanford University (Stanford, CA) when asked to explain the tremendous interest in capillary electrophoresis (CE). “You have to realize that most forms of high-performance liquid chromatography require non-aqueous solvents. So it's ...
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    Polymemse Chain Reaction Using Mixed Primers: Cloning of Human Monoclonal Antibody Variable Region Genes from Single Hybridoma Cells (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 934-938 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We describe a general approach to rapidly obtain the DNA sequence encoding the variable region of any immunoglobulin chain using the polymerase chain reaction and a mixture of upstream primers corresponding to the leader sequence, and one downstream primer designed from the conserved nucleotide ...
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    Microscopy and Image Analysis Products (1989)
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    Nature biotechnology 7 (1989), S. 957-958 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Densitometry Package Shimadzu Scientific Instruments (Columbia, MD) offers the QuantScan 2D software program and CS9000U scanning densitometer for acquiring and analyzing data from two-dimensional gels, thin-layer chromatography plates, blots, and autoradio-grams. Controlled with the Microsoft ...
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    Animal Welfare Taken Seriously (1989)
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    Nature biotechnology 7 (1989), S. 967-967 
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    Notes: [Auszug] To the editor: I am writing this letter with some trepidation since it is at risk of misinterpretation. I was very disturbed by “The First Word” (Bio/Technology 7:533 June '89). Although at first sight the article is amusing and was undoubtedly meant to be so, articles of this kind ...
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    IL-2 in Europe, Trade Groups to Merge? (1989)
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    Nature biotechnology 7 (1989), S. 745-748 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Denmark approves an interleukin. The announcement that Cetus (Emeryville, CA) may begin selling interleukin-2 (IL-2) there as a treatment for advanced renal-cell carcinoma comes less than six weeks after an advisory panel for the European Economic Community (EEC) recommended approval for the drug. ...
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    Critical U.K. Manpower Shortage Discussed (1989)
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    Nature biotechnology 7 (1989), S. 761-761 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—The demand for skilled manpower by Great Britain's biotechnology industry is likely to outstrip supply during the 1990s, according to a report by the U.K. Interest Group on Education in Biotechnology. The Group represents over 20 organizations—including the Royal Society of ...
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    Opinion: Reference Cell Lines (1989)
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    Nature biotechnology 7 (1989), S. 759-759 
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    Notes: [Auszug] Choosing the “right” bioreactor for growing one's particular cell line is getting harder all the time. There are more reactor designs available today, and plenty of data describing each one's performance characteristics. Yet very few of these studies use the same combination of cell ...
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    U.S/Japanese Biotech Coorporation (1989)
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    Nature biotechnology 7 (1989), S. 789-792 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] True or not, businessmen of all disciplines have long believed Japan to be procedurally slow, culturally complex, and possessing an impregnable distribution system. The central question now facing the biotech community is whether these stereotypical confines will help set the stage for yet another ...
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    Transgenic Tobacco Plants Expressing a Bacterial Detoxifying Enzyme are Resistant to 2,4-D (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 811-816 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We have used a gene from the soil bacterium Alcaligenes eutrophus JMP134 to introduce a herbicide degrading mechanism into plants. The gene, tfdA, which encodes a 2,4-dichlorophenoxyacetate monooxygenase (DPAM) catalyzing the first step in the bacterial 2,4-D degradative pathway, has recently been ...
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    Ultra-Thermostable Cellulases From Acidothermus cellulolyticus : Comparison of Temperature Optima with Previously Reported Cellulases (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 817-820 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The recent discovery of Acidothermus cellulolyticus genus novum, species novum, ATCC 43068, a moderately thermophilic, aerobic, cellulolytic bacterium in wood samples recovered from the acidic hot springs of northern Yellowstone National Park, Wyoming, affirms the notion that hitherto unknown ...
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    New Products (1989)
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    Nature biotechnology 7 (1989), S. 828-830 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Fraction Collector/Dialyzer InstruMed (Union Bridge, NJ) introduces the DiaFract-36, which combines column fraction collection with dialysis and concentration capabilities. Users may concentrate fractions with an osmotic agent, or first dialyze and then concentrate. Applications include rapid ...
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    Not As Easy As It Looked (1989)
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    Nature biotechnology 7 (1989), S. 629-629 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] A rosy glow has long suffused our vision of biotechnology in Japan: government support, public acceptance, highly motivated researchers, the happy reports of American research executives with joint development agreements—it sounded ideal, a model and a challenge. So it was a shock to ...
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    Social Policy Matters (1989)
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    Nature biotechnology 7 (1989), S. 840-840 
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    Notes: [Auszug] In 1988 the United States Patent and Trademark Office (PTO) issued the first patent on a vertebrate animal— the “Harvard mouse.” The PTO decision aroused considerable public response and protest, both upon review of the application and after granting the actual patent. While the ...
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    The Methionine Problem Solved, Ubiquitously (1989)
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    Nature biotechnology 7 (1989), S. 649-649 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Although biotechnologists have very successfully exploited microorganisms such as Escherichia coli and yeast as vehicles for producing a variety of eukaryotic proteins, there are still a number of difficulties to overcome before these genetically most-manipulable, and cost-efficient, expression ...
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    Opinion: Was It the Conference or the Climate? (1989)
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    Nature biotechnology 7 (1989), S. 655-655 
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    Notes: [Auszug] Arriving at the Annual Alex. Brown Health Care Seminar this past May, I carried little baggage—physical or otherwise. With the lineup for our June issue already set, there was none of the angst that often accompanies journalists hunting for a story—no space was reserved for meeting ...
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    Lymphokine Receptors as Therapeutics? (1989)
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    Nature biotechnology 7 (1989), S. 668-669 
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    Notes: [Auszug] For neuropharmacology, understanding how drugs interact with their receptors is already leading to a rational approach to drug design. For immunology, understanding the complexities of the cytokine/lymphokine network—the hormones, their cell-surface receptors, and the cellular responses they ...
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    Protein Folding Intermediates and Inclusion Body Formation. (1989)
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    Nature biotechnology 7 (1989), S. 690-697 
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    Notes: [Auszug] The accumulation of newly synthesized polypeptide chains expressed from cloned genes as non native aggregates has become an important factor in the recovery of such proteins. Studies of both the refolding of denatured proteins in vitro, and of in vivo folding and maturation pathways, indicate that ...
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    Screening of Muteins Secreted by Yeast: Random Mutagenesis of Human Interleukin-2 (1989)
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    Nature biotechnology 7 (1989), S. 716-720 
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    Notes: [Auszug] We have generated random variants of human interleukin-2 (hIL-2) and assayed them using a rapid method that is generally applicable to proteins secreted by yeast. Mutein screening is performed in three steps: (1) in vitro mutagenesis of the target gene and selection of mutant genes by a physical ...
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    Announcements (1989)
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    Nature biotechnology 7 (1989), S. 728-728 
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    Notes: [Auszug] JULY MEETINGS July 16–21. The 2nd International Conference on Health Law and Ethics. London, U.K. Info: British Medical Association, London '89, Tavistock Square, London WC1H 9JP, U.K. July 17–21. Advanced Techniques in Food Biotechnology. Lisbon, Portugal. Info: V. Loureiro, Dept. de ...
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    Can We Play, Too? (1989)
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    Nature biotechnology 7 (1989), S. 533-533 
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    Notes: [Auszug] It is painful to watch month after month while one's friends and professional acquaintances commercialize their research and carve out new markets. What, we ask ourselves, have they got that we haven't? They have companies (and stock options), and we want that, ...
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    Digesting Genzyme's Integrated Deal (1989)
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    Nature biotechnology 7 (1989), S. 544-544 
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    Notes: [Auszug] NEW YORK—Biotechnology companies get a lot of financial advice these days: Focus research only on areas where you can achieve a significant market position—areas that emphasize strengths in technology and/or production. Plan on financing long-term research with present revenues. Make ...
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    Interferon Trials Proliferate (1989)
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    Nature biotechnology 7 (1989), S. 549-549 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] HAVANA, Cuba—Research scientists the world over—including from Yugoslavia, Italy, U.S.S.R., Sweden, China, and Argentina—continue to explore the possible clinical applications of the interferons, both natural and recombinant. And in Cuba, more than 10,000 patients over the last ...
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    Japan Roundup (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 557-557 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Scientists at Tokyo's Kitasato Research Institute have isolated a novel cholesterol synthesis inhibitor from a strain of the fungus Scopulariopsis. Researchers in Satoshi Omura's group isolated and characterized the compound, designated A1233, last year. They found that it inhibits ...
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    Monocional Antibodies into the '90s: The All-Purpose Tool (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 567-573 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] FAb antibody fragments arrayed in a hypothetical p2 two-dimensional crystal. (Only C-alpha are shown, with each domain in a different color.) To meet the challenges of a dazzling array of antigens, the B cells of the immune system have developed mechanisms for producing antibodies from more than ...
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    Serum-Free Media Markets (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 574-575 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Many of today's—and tomorrow's—genetically engineered biologicals are being produced by cultured mammalian cells. As the number of real and potential products increases, so does the sheer volume of medium necessary to grow and maintain the billions of cells that make them. Basically, ...
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    A Novel Fungal Expression System: Secretion of Active Calf Chymosin from the Filamentous Fungus Trichoderma Reesei (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 596-603 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have studied the expression of a bovine chymosin cDNA in Trichoderma reesei to test the ability of this novel fungal host vector system to express and secrete heterologous gene products. Four different expression plasmids were constructed to determine the optimum manner to fuse the chymosin cDNA ...
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    New Products (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 613-616 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Diagen (Düsseldorf, F.R.G.) offers Qiagen plasmid kits for mini-, midi-, and maxipreps of high-purity plasmids. Kits include buffers and solutions for preparing plasmids as templates for sequencing reactions, cloning or transfection experiments, or other applications. Write in 601 on Reader ...
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    How Neurotransmitters Deliver the Message (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 407-407 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MIAMI, Fla.—How do neurotransmitters, operating at specific synapses on certain neurons, change behavior patterns? That question—central to neurobiology and neuropharmacology—remains unanswered. Even for those experiments conducted at the molecular and cellular level, “we ...
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    Lessons on Learning from Snails and Flies (1989)
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    Nature biotechnology 7 (1989), S. 409-411 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SAN FRANCISCO—“Memories are made of this…” What lyricists and poets already know, psychologists and molecular biologists are still trying to figure out. The molecular biologists, taking their clues from model systems as unlikely as flies and snails, have begun to dissect ...
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    Biotech's Major Impact Yet a Decade Away (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 420-420 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] PARIS—Biotechnology could, through rapid scientific and technical advances, become a net creator of employment beyond the next decade. Among developments contributing to this trend will be an increase in the number of new (rather than substitution) products in industry, innovations in ...
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    Ag Investors Growing Excited (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 423-423 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] ARLINGTON, Va.—The common wisdom says that biotech investments have been in the doldrums largely due to the effects of the 1987 stock market crash. The agribusiness sector, to many, is particularly adrift and rudderless. But don't tell that to the agri-venture capitalists and corporate ...
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    Hollow Fiber Bioreactors for Mammalian Cell Culture (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 459-461 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Hollow fiber bioreactors are growing in popularity as an alternative to tank-type systems. Although they have a few hurdles still to vault— notably sterility problems—hollow fiber systems offer many advantages: they support large numbers of mammalian cells in a small volume, they ...
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    Manufacturers: Equipment and Specifications (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 464-466 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] EQUIPMENT IN ORDER OF ASCENDING VOLUME Maker & Model Total Volume (Liters) Cell Type Equipment Type Anch Charles River Biotechnical Services Opticell 5200R (lab scale) m closed loop yes perfusion Wheaton MBF Fermentors 0.5 b, m, p stirred tank yes Ventrex Cellift 0.57 b, m, i loop ...
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    Expression of Human Anti-Hemophilic Factor IX in the Milk of Transgenic Sheep (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 487-492 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Transgenic livestock may prove useful for the large scale production of valuable proteins. By targeting expression to the mammary gland these proteins could be harvested from milk. To this end, we have designed a hybrid gene to direct the synthesis of human anti-hemophilic factor IX to the mammary ...
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    Transgenic Plants of Lettuce ( Lactuca sativa ) Obtained Through Electroporation of Protoplasts (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 503-508 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Protoplasts from adult leaves of lettuce were electroporated in osmotically adjusted and buffered solutions containing plasmid DNA of either pCAMV CAT or pABDl. Transient CAT activity measurements and selection for kanamycin resistance showed that expression of foreign genes and stable ...
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    Announcements (1989)
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    Nature biotechnology 7 (1989), S. 521-521 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MAY MEETINGS May 14–18. 89th Annual Meeting of the American Society for Microbiology. New Orleans, LA. Info: 1913 I St. NW, Washington, DC 20006. May 15–16. The 4th Princeton-Liposome Conference: From Bench to Bedside. Princeton, NJ. Info: P. Pluta, Conference Coordinator, The 4th ...
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    Biotech Products in Japanese Pipeline (1989)
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    Nature biotechnology 7 (1989), S. 326-327 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The U.S. Food and Drug Administration recently conducted a survey of Japanese biotechnology-derived pharmaceutical R&D. Eighty-four companies responded: They ranged from established, vertically integrated companies to those testing products obtained from foreign affiliates, as well as others ...
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    On Morphogenesis, Muscles, and Memory (1989)
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    Nature biotechnology 7 (1989), S. 323-324 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MIAMI, Fla.—Morphogenesis and learning both can be viewed as the acquisition, over time, of persistent patterns. And as participants at this year's Miami Bio/Technology Winter Symposium learned from Jean Pierre Changeux (Institut Pasteur, Paris) and Daniel Alkon (National Institutes of ...
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    Japan Roundup (1989)
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    Nature biotechnology 7 (1989), S. 332-332 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Thirty–six Japanese companies have agreed to participate in a program— under the auspices of the Japanese Ministry of Public Welfare—to develop drugs to treat AIDS (acquired immunodeficiency syndrome) and AIDS-related diseases. The research will focus on five areas: drugs to kill ...
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    UK Biotech Spending Spree, of a Sort (1989)
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    Nature biotechnology 7 (1989), S. 334-334 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—United Kingdom universities and research institutes will receive an extra $100 million of public funds for biotechnology-related research in 1989-1992. The money will provide major new support for programs in plant molecular biology, transgenic animals, protein engineering, ...
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    Recovery of Antigens From Immunoadsorbents Using High Pressure (1989)
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    Nature biotechnology 7 (1989), S. 369-373 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We report the use of pressures ranging to 2000 atm to elute bovine serum albumin from a moderate affinity monoclonal antibody immunoadsorbent (K = 2.4 × 107 M−1). Over 75 percent of reversibly bound protein was recovered following a single 15 minute incubation at 2000 atm, and over 90 ...
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    New Products (1989)
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    Nature biotechnology 7 (1989), S. 380-382 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A rapid method for T- and B- lymphocyte isolation uses Pan T (CD2) and Pan B (CD 19) monoclonal-antibody-coated Dynabeads™ from Dynal (Great Neck, NY). This immunomagnetic method speeds the isolation of lymphocytes into subsets; specific target cells, resetted with coated Dynabeads, can be ...
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    More Modeling Tools (1989)
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    Nature biotechnology 7 (1989), S. 386-386 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: The article “Dynamic Market Emerging for Molecular Modeling”(Bio/Technology 7: 43, Jan. '89) failed to mention one of the most exciting developments worldwide. Chemical Design (Oxford, U.K.) is using transputer-based computing “surfaces” from Meiko to build ...
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    Patents in Play: Suits and Settlements (1989)
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    Nature biotechnology 7 (1989), S. 199-202 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] While Amgen (Thousand Oaks, CA) awaits Food and Drug Administration (FDA) approval to market eryth-ropoietin (EPO) in the U.S., the company has been busy in court, asserting various claims against competitors it believes are infringing its patent. In January, the company unsuccessfully challenged ...
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    Serial RFLPs for Cereal Grains (1989)
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    Nature biotechnology 7 (1989), S. 211-211 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Five European seed companies will help U.K. plant scientists complete restriction fragment length polymorphism (RFLP) maps of wheat and barley, Europe's two major cereal crops. In return, over the next three years the companies will gain sole access to new RFLP probes and the maps they ...
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    R&D The Key to Danish Corporate Combination (1989)
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    Nature biotechnology 7 (1989), S. 211-212 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—A more natural merger than that planned for Nordisk Gentofte (Gentofte, Denmark) and Novo Industri (Bagsvaerd, Denmark), Denmark's two largest pharmaceutical companies, would be hard to imagine. Both are headquartered in the suburbs of Copenhagen, both have invested heavily in the ...
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    Japan Roundup (1989)
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    Nature biotechnology 7 (1989), S. 220-220 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Scientists at the Tokyo Metropolitan General Research Institute for Clinical Medicine have discovered that medroxyprogesterone acetate (MPA) can inhibit angiogenesis (the formation of new blood vessels). One hundred micrograms injected into chicken embryos (where it is easy to observe angiogenesis) ...
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    Biotherapy: A New Dimension in Cancer Treatment (1989)
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    Nature biotechnology 7 (1989), S. 231-240 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The biomedical community has spent the last 40 years searching for new and effective ways to treat cancer. During this time, research scientists have made great strides in understanding the nature of neoplastic cell transformation and the body's reaction to it. From this, new ways to treat cancer ...
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    The Genetic Engineering of Two Commercial Potato Cultivars for Resistance to Potato Virus X (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 273-278 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We efficiently transformed the commercial cultivars of potato (Solanum tuberosum) Bintje, Desiree and Escort after optimizing the conditions for regeneration from potato tuber discs. For transformation, tuber discs were cocultivated with Agrobacterium tumefaciens using a disarmed binary vector ...
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    Products for DNA Analysis (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 296-297 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Hybriwix™ probe systems use Diagnostic Hybrids' (Athens, OH) patented wicking technique for DNA purification and hybridization. This separation and purification method increases hybridization reactivity by providing higher retention of target DNA or RNA. Lysing, denaturing, and separating DNA ...
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    New Products (1989)
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    Nature biotechnology 7 (1989), S. 298-300 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Manufacturers of some of the following products are exhibiting at the Pittsburgh Conference (PITCON, March 6–10, Atlanta, GA) and at FASEB (March 19–24, New Orleans, LA). Molecular Dynamics (Sunnyvale, CA) introduces a high-resolution dynamic imaging instrument, the Autophoresis 1000A, ...
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    British Don't Buy Beef Ban (1989)
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    Nature biotechnology 7 (1989), S. 113-113 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Officially, the British government fully supports the European Community (EC) policy, now extended to imports, banning beef from cattle treated with steroid hormones. “Britain was party to the 1985 EC decision and acted upon the directive,” says a Ministry of Agriculture, ...
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    High Marks for U.K. Biotechnology Directorate (1989)
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    Nature biotechnology 7 (1989), S. 117-117 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—An independent review panel urges strong support for the seven-year-old U.K. Science and Engineering Research Council's (SERC) Biotechnology Directorate. Chaired by Tom Blundell of Birkbeck College (London), the 10-person panel consisted of seven academics, industry representatives ...
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    Proposed EPA Rules Go Another Round (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 122-122 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Last summer, draft biotechnology rules that the Environmental Protection Agency (EPA) sought to publish in the Federal Register seemed headed for early burial (Bio/Technology 6:1002, Sept. '88). By the new year, however, the proposals were given an unusual semi-official ...
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