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  • Nature Publishing Company
  • 1985-1989  (1,759)
  • 1
    Electronic Resource
    Electronic Resource
    Comparing the Efficacy of CSFs in Therapy (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 859-859 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] ORLANDO, Fla.—These are still the early days of immunotherapy, but clinicians and researchers alike respect the fact that they are playing with a new set of rules—even if they don't know what they all are yet. Still, some of the differences between chemotherapy and immunotherapy are ...
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    URL: http://dx.doi.org/10.1038/nbt0989-859
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  • 2
    Electronic Resource
    Electronic Resource
    NIH Invention Development Program Advances (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 866-866 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—With some 5,000 researchers at its disposal, the National Institutes of Health (NIH, Bethesda, MD) churns out a great deal of biomedical know-how—much of it with commercial potential. To realize this potential more fully, NIH and other Public Health Service (PHS) ...
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    URL: http://dx.doi.org/10.1038/nbt0989-866
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  • 3
    Electronic Resource
    Electronic Resource
    1989 Compensation Survey (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 875-880 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] At the beginning of July, Bio/Technology sent questionnaires to a cross-section of readers, 671 in the United States and 259 in Europe. We received 304 U.S. responses in time for this report, of which 293 were complete enough to be included in this analysis. Because of postal delays and the added ...
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    URL: http://dx.doi.org/10.1038/nbt0989-875
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  • 4
    Electronic Resource
    Electronic Resource
    Homologies in the Structures of G-Binding Proteins: An Analysis Based on Elongation Factor EF-TU (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 913-920 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The defining property of G binding proteins is their ability to bind guanine nucleotides, and in this review we shall concentrate upon the domain or subunit responsible for carrying out this function. A common function of such a general nature, exercised in so many different biological organisms ...
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    URL: http://dx.doi.org/10.1038/nbt0989-913
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  • 5
    Electronic Resource
    Electronic Resource
    Enkephalins Prouduced in Transgenic Plants Using Modified 2S Seed Storage Proteins (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 929-932 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have explored the possibility of producing large amounts of biologically active peptides as part of chimeric plant seed storage proteins, the 2S albumins. A portion of an Arabidopsis thaliana 2S albumin gene, encoding a region of the protein whose sequence is not highly conserved among different ...
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    URL: http://dx.doi.org/10.1038/nbt0989-929
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  • 6
    Electronic Resource
    Electronic Resource
    Patent Fights Generating Late Summer Heat (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 849-851 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Some suing, one settling. The hottest item this month is the start of the long-awaited trial between Amgen (Thousand Oaks, CA) and Genetics Institute (Cambridge, MA) over patent rights to erythropoietin (EPO). While the parties may indeed be negotiating a settlement behind the scenes (presumably a ...
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    URL: http://dx.doi.org/10.1038/nbt0989-849
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  • 7
    Electronic Resource
    Electronic Resource
    Role for Public Interest Groups Discussed (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 860-860 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] OXFORD, U.K.—As the U.K. government prepares to publish legislative proposals concerning the release of genetically engineered organisms into the environment, it is facing calls from prominent biotechnologists for public interest groups to be actively involved in the regulatory process. The ...
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    URL: http://dx.doi.org/10.1038/nbt0989-860
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  • 8
    Electronic Resource
    Electronic Resource
    Japan Roundup (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 870-870 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Scientists at Kewpie Jyozo Co., Ltd. (Tokyo), working in collaboration with Tokyo Metropolitan University's Katsutoshi Yoshisato, have isolated a novel cell growth and adhesion factor from the membranes that line the inner surface of egg shells. This factor stimulates the growth of cultured human ...
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    URL: http://dx.doi.org/10.1038/nbt0989-870
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  • 9
    Electronic Resource
    Electronic Resource
    Opinion: Reference Cell Lines (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 759-759 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Choosing the “right” bioreactor for growing one's particular cell line is getting harder all the time. There are more reactor designs available today, and plenty of data describing each one's performance characteristics. Yet very few of these studies use the same combination of cell ...
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    URL: http://dx.doi.org/10.1038/nbt0889-759
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  • 10
    Electronic Resource
    Electronic Resource
    Protein Patent Problem to Hinder Research? (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 764-764 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BERNE, Switzerland—Will the commercial development and patenting of useful pharmacologically active proteins cease, once substantial parts of the human genome have been sequenced? The question was raised by Norman Carey, director of scientific affairs at Celltech (Slough, U.K.), during a ...
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    URL: http://dx.doi.org/10.1038/nbt0889-764b
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  • 11
    Electronic Resource
    Electronic Resource
    Direct Somatic Embryogenesis in Peanut (Arachis Hypogea) (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 949-951 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have regenerated plants of Arachis hypogea cultivar SB-11 from immature zygotic embryo axis via direct somatic embryogenesis without an intermediate callus stage. Induction and maturation of the somatic embryos was achieved on the same medium. 2,4-dichlorophenoxy acetic acid (2,4-D) was ...
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    URL: http://dx.doi.org/10.1038/nbt0989-949
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  • 12
    Electronic Resource
    Electronic Resource
    Amgen Drug Approved, Rivals Remain Riled (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 635-638 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] At long last, EPO. On June 1, the Food and Drug Administration (FDA) approved Amgen's (Thousand Oaks, CA) recombinant erythropoietin (EPO) for use in treating anemia associated with chronic renal failure. For the time being, only Amgen can sell the drug in the U.S., but disputes with both its ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0789-635
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  • 13
    Electronic Resource
    Electronic Resource
    Missing Microbial (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 967-967 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: It was delight turned chagrin when I picked up the May '89 issue of Bio/Technology and found your article “Microbial Product Discovery in the Biotech Age” (Bio/Technology 7:427, May '89). My delight quickly faded as I failed to find reference to Panlabs Inc., which is ...
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    URL: http://dx.doi.org/10.1038/nbt0989-967c
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  • 14
    Electronic Resource
    Electronic Resource
    IL-2 in Europe, Trade Groups to Merge? (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 745-748 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Denmark approves an interleukin. The announcement that Cetus (Emeryville, CA) may begin selling interleukin-2 (IL-2) there as a treatment for advanced renal-cell carcinoma comes less than six weeks after an advisory panel for the European Economic Community (EEC) recommended approval for the drug. ...
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    URL: http://dx.doi.org/10.1038/nbt0889-745
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  • 15
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    Electronic Resource
    Screening of Muteins Secreted by Yeast: Random Mutagenesis of Human Interleukin-2 (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 716-720 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have generated random variants of human interleukin-2 (hIL-2) and assayed them using a rapid method that is generally applicable to proteins secreted by yeast. Mutein screening is performed in three steps: (1) in vitro mutagenesis of the target gene and selection of mutant genes by a physical ...
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    URL: http://dx.doi.org/10.1038/nbt0789-716
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  • 16
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    Electronic Resource
    Free Literature (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 727-727 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] VWR Scientific (San Francisco, CA) introduces the VWR Safety Showcase catalog, featuring descriptions and photos of personal protection and employee safety products for science and industry. Write in 701 on Reader Service Card A color brochure from JM Science (Buffalo, NY) describes recycling ...
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    URL: http://dx.doi.org/10.1038/nbt0789-727
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  • 17
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    Silent Science (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 534-534 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Injured pride, even in small quantities, is a dubious starting point for a rational discussion of anything. So I have waited several months before telling the story of the scientific meeting I was not permitted to attend—months in which, though the pique has dispersed, my perplexity has grown ...
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    URL: http://dx.doi.org/10.1038/nbt0689-534
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  • 18
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    New Filtration Products (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 826-827 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Vacuum Cleaner The model GS 801 from Nifilsk (Malvern, PA) cleans production areas such as those used in large-scale mammalian cell culture facilities. The compact filtration device weighs under 15 lb. and can hold up to 3.25 gal. of dry bulk. When equipped with HEPA filters, it collects and ...
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    URL: http://dx.doi.org/10.1038/nbt0889-826
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  • 19
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    Filtering Out Inhibition (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 462-463 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Since the birth of hollow fiber bioreactor technology in the 1970s1, this method for growing cells in a three-dimensional environment similar to solid tissues has proved useful for recovering products secreted by cells2. By using ultrafiltration membrane-based hollow fiber cartridges with low ...
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    URL: http://dx.doi.org/10.1038/nbt0589-462
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  • 20
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    Japan Roundup (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 332-332 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Thirty–six Japanese companies have agreed to participate in a program— under the auspices of the Japanese Ministry of Public Welfare—to develop drugs to treat AIDS (acquired immunodeficiency syndrome) and AIDS-related diseases. The research will focus on five areas: drugs to kill ...
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    URL: http://dx.doi.org/10.1038/nbt0489-332
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  • 21
    Electronic Resource
    Electronic Resource
    Watson's Great Human Chromosome Auction (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 559-559 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—The mammoth project of mapping and sequencing the human genome (Bio/Technology 7:223, Mar. '89) might best be managed by “auctioning off the chromosomes”—perhaps country by country, suggests James Watson, director of the Cold Spring Harbor Laboratory (Cold ...
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    URL: http://dx.doi.org/10.1038/nbt0689-559
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  • 22
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    A Prospectus for Multispectral-Multiplex DNA Sequencing (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 576-580 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] First-generation automated DNA sequencers are based on operations, manipulations, and methodologies not unlike those performed by their human predecessors. While these instruments may reduce labor, they do not increase sequencing rates by exponential factors. Here we review several new ...
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    URL: http://dx.doi.org/10.1038/nbt0689-576
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  • 23
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    Electronic Resource
    Enzyme Immobilization Using the Cellulose-Binding Domain of a Cellulomonas Fimi Exoglucanase (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 604-607 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have constructed a fusion between the gene (abg) for a β-glucosidase (Abg) of an Agrobacterium sp. and part of the gene (cex) for an exoglucanase (Cex) of Cellulomonas fimi. The abg-cex fusion encodes a fusion protein (Abg-CBDCex) with the cellulose-binding properties of Cex and ...
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    URL: http://dx.doi.org/10.1038/nbt0689-604
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  • 24
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    Electronic Resource
    Name-Calling (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 197-197 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In the beginning, of course, was the Word. And the creation was a process of naming names and pronouncing judgment…by saying, it became so. The first man affirmed his proprietorship of the beasts, birds, and fishes by giving them their names. The first-comers to any frontier have this ...
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    URL: http://dx.doi.org/10.1038/nbt0389-197
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  • 25
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    Announcements (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 618-618 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] JUNE MEETINGS June 18–21. 16th Annual International Health Conference. Arlington, VA. Info: 1989 Member Conference Registration, National Council for International Health, Suite 600, 1701 K St. NW, Washington, DC 20006. June 19–20. Drugs Affecting Ion Channels. Boston, MA. Info: ...
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    URL: http://dx.doi.org/10.1038/nbt0689-618
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  • 26
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    Major Mergers, Crop Companies Combine (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 401-404 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Beecham moves in, Beckman out.The Philadelphia, PA-based firm SmithKline Beckman (SKB) and Beecham Group PLC (London, U.K.) will merge. The new entity—SmithKline Beecham PLC—will become the second-largest pharmaceutical company in the world, based on combined 1988 revenues of ...
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    URL: http://dx.doi.org/10.1038/nbt0589-401
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  • 27
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    Electronic Resource
    Debate Continues on Patenting Organisms (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 414-414 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Representative Robert Kastenmeier (D-WI) reintroduced in March two bills from 1988 addressing transgenic animal issues—one calls for restrictions on the applicability of patents to farm animal use, and the other asks for a new federal regulatory regime for all ...
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    URL: http://dx.doi.org/10.1038/nbt0589-414
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  • 28
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    RFLP Mapping in Plant Breeding: New Tools for an Old Science (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 257-264 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Breeders have traditionally improved plant varieties by selecting on the basis of phenotype. Now restriction fragment length polymorphism (RFLP) linkage maps are being constructed for most major crop plants and these maps provide a more direct method for selecting desirable genes via their linkage ...
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    URL: http://dx.doi.org/10.1038/nbt0389-257
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  • 29
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    Novel Expression of Chimeric Plasminogen Activators in Insect Cells (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 286-292 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The isolated protease domain of single chain urokinase–type plasminogen activator (scu–PA) preferentially activates fibrin–associated plasminogen in plasma, yet scu–PA binds poorly to forming fibrin clots. We are investigating the effect of combining this protease domain ...
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    URL: http://dx.doi.org/10.1038/nbt0389-286
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  • 30
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    Free Literature (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 301-301 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Titration in Progress, a 16-page color pamphlet from Radiometer Analytical A/S (Bagsvaerd, Denmark), provides a survey of systems, including titration for water analysis, COD determinations, and pH control. The brochure, outlining selection criteria, is available in both English and German. Write ...
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  • 31
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    Company Pacts Signal Commercial Progress (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 107-108 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Hambrecht & Quist (H & Q, San Francisco, CA) Seventh Annual Healthcare Conference provided the forum for a slew of corporate announcements. Among them, Cetus (Emeryville, CA) and Hoffmann-La Roche (Roche, Nutley, NJ) will collaborate on the development and commercialization of human ...
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    URL: http://dx.doi.org/10.1038/nbt0289-107
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  • 32
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    Implantable Glucose Sensor Expected Soon (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 116-116 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] GöHREN, G.D.R.—For patients afflicted with insulin-dependent diabetes mellitus (IDDM), controlling blood glucose at near-normal levels can best reduce the disease's long-term, life-threatening cardiovascular side effects. An implantable glucose sensor would greatly aid in controlling ...
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  • 33
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    Human Disease Genes Elude Identification (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 120-120 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TORONTO, Ont.—“On Chorea,” the only scientific treatise by Long Island, NY physician George Huntington, is over a century old. Yet, despite decades of concentrated effort by scores of research scientists, the gene that causes Huntington's disease remains unidentified. So, too, for ...
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  • 34
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    New Products (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 298-300 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Manufacturers of some of the following products are exhibiting at the Pittsburgh Conference (PITCON, March 6–10, Atlanta, GA) and at FASEB (March 19–24, New Orleans, LA). Molecular Dynamics (Sunnyvale, CA) introduces a high-resolution dynamic imaging instrument, the Autophoresis 1000A, ...
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    Crop Biotech '89: Research Efforts are Market Driven (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 337-341 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Investing in an unproven research area entails a considerable economic risk. Outside capital is limited, and corporations today are definitely risk averse, forcing biotech companies to devote their resources to fewer and more targeted projects—usually those with well-defined prospects for ...
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    High Expression in Mammalian Cells Without Amplification (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 359-362 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have used mammalian cell lines, constructed with the expression system described, to express high levels of a heterologous gene product (human growth hormone) without recourse to gene amplification. The system employs commonly available components that combine efficiently to yield high ...
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    New Products (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 380-382 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] A rapid method for T- and B- lymphocyte isolation uses Pan T (CD2) and Pan B (CD 19) monoclonal-antibody-coated Dynabeads™ from Dynal (Great Neck, NY). This immunomagnetic method speeds the isolation of lymphocytes into subsets; specific target cells, resetted with coated Dynabeads, can be ...
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    End-User Searching of Biotech Databases (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 378-379 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Database searching, once confined to the ranks of information specialists and trained librarians, is becoming a research tool that anyone can use with a minimum of preparation. Offered by several commercial database vendors, end-user systems guide the uninitiated through on-line searches. These ...
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    More Modeling Tools (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 386-386 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: The article “Dynamic Market Emerging for Molecular Modeling”(Bio/Technology 7: 43, Jan. '89) failed to mention one of the most exciting developments worldwide. Chemical Design (Oxford, U.K.) is using transputer-based computing “surfaces” from Meiko to build ...
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    Patents in Play: Suits and Settlements (1989)
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    Nature biotechnology 7 (1989), S. 199-202 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] While Amgen (Thousand Oaks, CA) awaits Food and Drug Administration (FDA) approval to market eryth-ropoietin (EPO) in the U.S., the company has been busy in court, asserting various claims against competitors it believes are infringing its patent. In January, the company unsuccessfully challenged ...
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    Biotech: Experimental Subject (1989)
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    Nature biotechnology 7 (1989), S. 216-216 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Two Cornell University (Ithaca, NY) professors are attempting to determine the most effective ways to finance and manage the transfer of basic biotechnology research to the marketplace. In a study expected to take three to five years, John Freeman of the Johnson School of Management ...
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    Genetic Variation in Wheat HMW Glutenin Subunits and the Molecular Basis of Bread-Making Quality (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1281-1285 
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    Notes: [Auszug] For successful bread-making, dough made from wheat flour needs to have considerable elasticity. The elasticity is provided in part by seed storage proteins called high molecular weight (HMW) glutenin subunits. Two particular HMW subunits, numbers 12 and 10 have been found previously to confer ...
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    Immunex Turns a Triple Play (1989)
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    Nature biotechnology 7 (1989), S. 1115-1117 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—A series of bold strategic moves announced in September by Immunex (Seattle, WA) has left analysts buzzing and the company's stock price inching higher. By reacquiring proprietary rights it previously had traded away to its partners—in particular North American marketing rights ...
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    Sometimes a Great Motion (1989)
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    Nature biotechnology 7 (1989), S. 1121-1122 
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    Notes: [Auszug] Mobile DNA. Edited by D. Berg and M. Howe. Pp. 972. ISBN 1-55581-005-5. $75.00 (American Society for Microbiology, Washington, D.C.: 1989). How does selfish DNA behave? What's today's thinking on the evolution of chromosome structure? How are mutagenic mobile elements regulated? Mobile DNA ...
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    Production of Leukemia Inhibitory Factor in Escherichia coli by a Novel Procedure and Its Use in Maintaining Embryonic Stem Cells in Culture (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1157-1161 
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    Notes: [Auszug] Leukemia inhibitory factor [LIF] is a glycoprotein that is able to induce the differentiation of M1 myeloid leukemic cells and prevent the differentiation of murine embryonic stem [ES] cells. This report presents a simple method for the production and purification of large amounts of recombinant ...
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    Increased Biomass Production in a Benchtop Fermentor (1989)
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    Nature biotechnology 7 (1989), S. 1178-1181 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Optimization of a fermentation process means different things in different situations. One may optimize for nutrient consumption (as in waste treatment), for product output, or for biomass production. For any of these goals, the main development paths are 1) biological approaches, in which ...
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    Free Literature (1989)
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    Nature biotechnology 7 (1989), S. 1192-1192 
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    Notes: [Auszug] Cryopreservation. Cole-Parmer (Chicago, IL) has a new brochure highlighting its biological mini-freezer, cryogenic refrigerator, Locator™ sample inventory system, controlled-rate freezing elevator, and micro-cooling bath. Write in 701 on Reader Service Card Chromatography. Alltech ...
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    Announcements (1989)
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    Nature biotechnology 7 (1989), S. 1247-1247 
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    Notes: [Auszug] DECEMBER MEETINGS Dec. 17–22. The 1989 International Chemical Congress of Pacific Basin Societies. Honolulu, Hawaii. Info: Nancy En-right, American Chemical Society, News Service, Rm 211, 1155 Sixteenth St. N.W., Washington, DC 20036. Dec. 20. The Terminology of Biotechnology: A ...
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    Merged Novo-Nordisk on the Right Course (1989)
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    Nature biotechnology 7 (1989), S. 1006-1006 
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    Notes: [Auszug] LONDON—Novo-Nordisk (Bagsvaerd, Denmark), the pharmaceuti-cals and biotechnology group formed earlier this year following a merger between Novo Industri and Nordisk Gentofte, has reported its first financial results. The new company achieved a 17-percent increase in sales, to $493 ...
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    Dealing with Large Companies (1989)
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    Nature biotechnology 7 (1989), S. 1013-1019 
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    Notes: [Auszug] A merger is like a marriage, while a collaboration is closer to cohabitation. Both agreements bring the parties close together, and both can be highly fulfilling. But one route clearly offers more freedom and independence to pursue other interests. While it is up to the parties to decide, case by ...
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    Low Frequency Restriction Enzymes in Pulsed Field Electrophoresis (1989)
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    Nature biotechnology 7 (1989), S. 1033-1036 
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    Notes: [Auszug] Pulsed field electrophoresis (PFE) separates very large DNA fragments—even whole chromosomes. It does this not by the usual gel sieving mechanism, but rather by taking advantage of the size dependence of reorientation times for molecules forced to migrate alternately in two different ...
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    New Products (1989)
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    Nature biotechnology 7 (1989), S. 960-964 
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    Notes: [Auszug] Retinoblastoma Antibody PharMingen (San Diego, CA) will make available monoclonal antibodies specific for the human retinoblastoma (RB) gene product, a protein thought to be important in cancer suppression and cell growth regulation. These antibodies immunoprecipitate authentic RB proteins, are ...
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    Will Research Success Increase Risk of Bias? (1989)
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    Nature biotechnology 7 (1989), S. 753-753 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Because of their growing potential for commercial payoffs, federally sponsored bio-medical research programs are coming under sharp scrutiny. Borderlines between basic and applied commercial research have blurred, raising concerns that increased numbers of researchers are ...
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    Critical U.K. Manpower Shortage Discussed (1989)
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    Nature biotechnology 7 (1989), S. 761-761 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—The demand for skilled manpower by Great Britain's biotechnology industry is likely to outstrip supply during the 1990s, according to a report by the U.K. Interest Group on Education in Biotechnology. The Group represents over 20 organizations—including the Royal Society of ...
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    Japan Roundup (1989)
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    Nature biotechnology 7 (1989), S. 766-766 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Scientists at the Industrial Research Council's Research Institute for Techniques in Industrial Microbiology (Tokyo) have discovered a new biopolymer that can absorb 500 times its own weight in salt water. Its ability to absorb fresh water is even greater—one gram can absorb one liter. Unlike ...
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    Growth Factors For Wound Healing (1989)
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    Nature biotechnology 7 (1989), S. 793-798 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The process of wound healing begins immediately following surface lesions or when skin proteins become exposed to radiation, chemical damage or extreme temperatures. Wound repair requires close control of degradative and regenerative processes, involving numerous cell types and complex interactions ...
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    Ultra-Thermostable Cellulases From Acidothermus cellulolyticus : Comparison of Temperature Optima with Previously Reported Cellulases (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 817-820 
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    Notes: [Auszug] The recent discovery of Acidothermus cellulolyticus genus novum, species novum, ATCC 43068, a moderately thermophilic, aerobic, cellulolytic bacterium in wood samples recovered from the acidic hot springs of northern Yellowstone National Park, Wyoming, affirms the notion that hitherto unknown ...
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    New Products (1989)
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    Nature biotechnology 7 (1989), S. 828-830 
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    Notes: [Auszug] Fraction Collector/Dialyzer InstruMed (Union Bridge, NJ) introduces the DiaFract-36, which combines column fraction collection with dialysis and concentration capabilities. Users may concentrate fractions with an osmotic agent, or first dialyze and then concentrate. Applications include rapid ...
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    Not As Easy As It Looked (1989)
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    Nature biotechnology 7 (1989), S. 629-629 
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    Notes: [Auszug] A rosy glow has long suffused our vision of biotechnology in Japan: government support, public acceptance, highly motivated researchers, the happy reports of American research executives with joint development agreements—it sounded ideal, a model and a challenge. So it was a shock to ...
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    The Methionine Problem Solved, Ubiquitously (1989)
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    Nature biotechnology 7 (1989), S. 649-649 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Although biotechnologists have very successfully exploited microorganisms such as Escherichia coli and yeast as vehicles for producing a variety of eukaryotic proteins, there are still a number of difficulties to overcome before these genetically most-manipulable, and cost-efficient, expression ...
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    Opinion: Was It the Conference or the Climate? (1989)
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    Nature biotechnology 7 (1989), S. 655-655 
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    Notes: [Auszug] Arriving at the Annual Alex. Brown Health Care Seminar this past May, I carried little baggage—physical or otherwise. With the lineup for our June issue already set, there was none of the angst that often accompanies journalists hunting for a story—no space was reserved for meeting ...
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    Regional Development: The Role and Effectiveness of Governmental Agencies (1989)
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    Nature biotechnology 7 (1989), S. 671-683 
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    Notes: [Auszug] In the early 1980s, the national mood concerning the commercial potential of biotechnology was decidedly upbeat. Every region of the country saw itself as the hub of a great new industrial machine, rivalling the success of California and Massachusetts in establishing a high-tech identity. As far ...
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    Expression of Human β1 and β2 Adrenergic Receptors in E. Coli As a New Tool for Ligand Screening (1989)
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    Nature biotechnology 7 (1989), S. 923-927 
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    Notes: [Auszug] E. coli transformed with appropriate plasmid vectors express human β1 and β2-adrenergic receptors that retain the binding properties of the corresponding receptors in mammalian tissues. The experimental procedure required for pharmacological studies on active receptors expressed in ...
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    Proposed Rules for Deposits (1989)
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    Nature biotechnology 7 (1989), S. 556-556 
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    Notes: [Auszug] ST. LOUIS, Mo.—In October 1988, the U.S. Patent and Trademark Office (PTO) proposed a new set of rules in Title 37 of the Code of Federal Regulations, sections 1.200-208. These rules, which probably will be finalized in July and become effective next January, will govern deposits of ...
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    Non-Transformed Cell Lines: The Problems of Being Human (1989)
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    Nature biotechnology 7 (1989), S. 561-563 
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    Notes: [Auszug] Mammalian cells—especially human cells—are complicated entities we understand only imperfectly. Yet often they are the only appropriate sources from which to isolate therapeutic compounds. And for expressing genetically engineered human proteins that require absolute fidelity of ...
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    Amgen, GI Heading for Patent Showdown (1989)
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    Nature biotechnology 7 (1989), S. 764-764 
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    Notes: [Auszug] NEW YORK—The battle between Amgen (Thousand Oaks, CA) and Genetics Institute (GI, Cambridge, MA) over patent rights relating to the invention and production of recombinant erythropoietin (EPO) is rapidly coming to a head—on multiple fronts. Trial dates are scheduled in both ...
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    Biotechnology Falls Foul of the Environment in the USSR (1989)
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    Nature biotechnology 7 (1989), S. 783-788 
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    Notes: [Auszug] Until last month, industrial biotechnology was a rapidly growing sector of the Soviet economy. But now, nation-wide environmental protests have forced the government to abandon its single cell protein (SCP) program, which involves over 100 production facilities. Construction projects costing ...
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    Functional Expression of Human Monoclonal Antibody Genes Directed Against Pseudomonal Exotoxin A in Mouse Myeloma Cells (1989)
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    Nature biotechnology 7 (1989), S. 805-810 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We have cloned immunoglobulin (Ig) genes from an Epstein-Barr (EB) virus-transformed human B cell line, FK-001, which produced a monoclonal human IgM that specifically binds Pseudomonas aeruginosa exotoxin A (Ex-A). Cloned Ig genomic DNA was introduced into Ig non-producing mouse myeloma cells, ...
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    Composite Filters for the Lab (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 825-825 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Filtration is a universal step for cleaning up samples before chromatography or other analytical procedures. An effective filtration process improves the accuracy of subsequent steps and extends the lifetime of more expensive separation media. But filtration is difficult with protein-rich fluids, ...
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    Social Policy Matters (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 840-840 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In 1988 the United States Patent and Trademark Office (PTO) issued the first patent on a vertebrate animal— the “Harvard mouse.” The PTO decision aroused considerable public response and protest, both upon review of the application and after granting the actual patent. While the ...
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    Genome Technology: What Will It All Mean? (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 639-649 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SANTA MARGHERITA LIGURE, Italy—The impact of the newer genome technologies on our understanding of human genetics was the focus of the European Molecular Biology Organization (Heidelberg, F.R.G.)-International School of Pediatric Sciences (Genoa, Italy) joint workshop held here recently. One ...
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    Of Bioprogramming, and a New Program (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 654-654 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Neutering agents (successful in early animal trials), a possible synthetic peptide-based vaccine for acquired immunodeficiency syndrome, a new polymer anti-skid runway coating, and a compound for treating prostate cancer, are four patented developments to emerge thus far from the ...
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    Lymphokine Receptors as Therapeutics? (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 668-669 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] For neuropharmacology, understanding how drugs interact with their receptors is already leading to a rational approach to drug design. For immunology, understanding the complexities of the cytokine/lymphokine network—the hormones, their cell-surface receptors, and the cellular responses they ...
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    Renaturation and Purification of Biologically Active Recombinant Human Macrophage Colony-Stimulating Factor Expressed in E. Coli (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 710-715 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Recombinant human macrophage colony-stimulating factor (M-CSF), a disulfide-linked dimeric protein containing 18 cysteines, has been purified in monomeric form from E. coli and renatured to generate fully active dimers with an overall yield of 25 percent. M-CSF monomers were quantitatively refolded ...
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    Coming Clean (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 317-317 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Joshua Lederberg does it right. Whenever we have heard him publicly address a public issue, the Nobel Prize winner and president of the Rockefeller University has prefaced his comments with a resume of his own biases—including a list of those commercial ventures in which he has an interest. ...
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    Corn: From Protoplasts to Fertile Plants (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 548-548 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Plant biotechnologists have taken another important step towards the genetic engineering of maize. Two papers in this issue of Bio/Technology report the regeneration of fertile corn plants from protoplasts. Although our group had previously demonstrated the regeneration of mature plants from the ...
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    Of EPA, Risks, and Rule Making (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 555-555 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—The specter of biotechnology gone amok continues to haunt the Environmental Protection Agency (EPA). Charged under the Toxic Substances Control Act (TSCA) with regulating the commercial use of microorganisms, the agency does not want to risk public disapproval by appearing to ...
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    Measuring Contaminating DNA in Bioreactor Derived Monoclonals (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 343-347 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Pharmaceutical manufacturers need to accurately quantity picogram amounts of contaminating DNA in recombinant proteins and monoclonal antibodies intended for therapeutic use. Generally, this requires an assay capable of detecting 10 picograms or less of contaminating DNA per dose of product. ...
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    Bacterial Expression, Facile Purification and Properties of Recombinant Human Lymphotoxin (Tumor Necrosis Factor Beta) (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 363-368 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have expressed a synthetic recombinant human TNF–β(rhTNF–β) gene in Escherichia coli to give rhTNF–β in a soluble, highly active and intact form. The specific activity of rhTNF–β purified in a single, convenient step from bacterial lysates was ...
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    Immobilization Methods for Piezoelectric Biosensors (1989)
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    Nature biotechnology 7 (1989), S. 349-351 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Conceptually, biosensors are relatively simple measuring devices that incorporate a biologically active sensing material into a transducer. In practice, researchers continue to search for ideal combinations of biocatalysts—enzymes, antibodies, antigens, bacteria, whole cells, plant slices, ...
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    Free Literature (1989)
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    Nature biotechnology 7 (1989), S. 617-617 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Pierce Europe (Oud-Beijerland, The Netherlands) introduces its 1989 handbook and general catalog, which lists over 1,000 products for chromatography and immunology. This year's volume includes 230 antibody and detection systems. Write in 701 on Reader Service Card The six-page 1989 price list ...
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    Success in Engineering E. Coli Secretion (1989)
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    Nature biotechnology 7 (1989), S. 209-209 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A bicomponent system for secreting foreign proteins from E. coli. One plasmid expresses bacteriocin release protein (BRP) that renders the outer membrane permeable. The other encodes the synthesis of human growth hormone (hGH) fused to a signal peptide (OmpA), allowing the hormone to enter the ...
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    A Ray of Hope for Animal Patents in Europe (1989)
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    Nature biotechnology 7 (1989), S. 221-221 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] ITHACA, N.Y.—One topic generating much discussion at the Cornell University Animal Patent Symposium, held here in December, was inventors' frustrations at their inability to patent higher plants and animals in Europe. Although most of the symposium dealt with U.S. patent issues and their ...
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    The Genetic Engineering of Two Commercial Potato Cultivars for Resistance to Potato Virus X (1989)
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    Nature biotechnology 7 (1989), S. 273-278 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We efficiently transformed the commercial cultivars of potato (Solanum tuberosum) Bintje, Desiree and Escort after optimizing the conditions for regeneration from potato tuber discs. For transformation, tuber discs were cocultivated with Agrobacterium tumefaciens using a disarmed binary vector ...
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    Efficient Degradation of Trichloroethylene by a Recombinant Escherichia Coli (1989)
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    Nature biotechnology 7 (1989), S. 282-285 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We have identified a strain of Pseudomonas mendocina that oxidizes trichloroethylene (TCE) after growth in the presence of toluene. A DNA fragment from this organism, when introduced into the appropriate expression vector system, conferred upon Escherichia coli the ability to oxidize both toluene ...
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    New Clues on Folding (1989)
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    Nature biotechnology 7 (1989), S. 324-325 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SAN FRANCISCO—Some experimental model systems are as comfortable and familiar to scientists as old friends. Generations of geneticists and molecular biologists have been raised on bacterial enzymes—such as tryptophan synthase—and bacterial viruses—such as phage f1. What more ...
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    British Don't Buy Beef Ban (1989)
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    Nature biotechnology 7 (1989), S. 113-113 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—Officially, the British government fully supports the European Community (EC) policy, now extended to imports, banning beef from cattle treated with steroid hormones. “Britain was party to the 1985 EC decision and acted upon the directive,” says a Ministry of Agriculture, ...
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    Genentech: Don't Sell the Company Short (1989)
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    Nature biotechnology 7 (1989), S. 114-114 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] SAN FRANCISCO—The tissue plasminogen activator (t-PA) saga has been the Genentech (So. San Francisco, CA) story over the past year. There is more, however, to Genentech's business development strategy. Two announcements made here in January—the planned development and distribution of ...
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    Biotech in Full Bloom at Coast Conference (1989)
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    Nature biotechnology 7 (1989), S. 119-119 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] SAN FRANCISCO—A mixture of pragmatism and optimism imbued the Hambrecht & Quist Seventh Annual Health Care Conference held here January 9–11. Among the 140 presenting companies numbered 40 biotechnology companies and two major pharmaceutical firms—Glaxo (London) and Squibb ...
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    USDA Panel Evaluates Cattle Vaccine Test (1989)
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    Nature biotechnology 7 (1989), S. 123-123 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] WASHINGTON, D.C.—The Agricultural Biotechnology Research Advisory Committee (ABRAC), still negotiating its proper mandate, also for the first time tackled a far more concrete issue during its meeting early in January at U.S. Department of Agriculture (USDA) headquarters. The committee ...
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    Claim Language in Biotechnology Patents (1989)
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    Nature biotechnology 7 (1989), S. 138-140 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Before the discovery of DNA or the creation of genetic engineering, Judge Learned Hand said that drafting good patent claims is one of the most difficult tasks in all of law. Molecular biology has added another layer, indeed another dimension, of tremendous complexity and difficulty to that job. ...
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    Big vs. Little (1989)
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    Nature biotechnology 7 (1989), S. 1248-1248 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] To the editor: You seem to concentrate on the spectacular success stories of transference like Genentech, some of the firms along Route 128 in Boston, or the California companies. How about talking about some of the losers…the little guys who tried it with little or no money and almost made ...
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    Protection Against Potyvirus Infection in Transgenic Plants: Evidence for Broad Spectrum Resistance (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1257-1262 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Expression in transgenic plants of the coat protein (CP) gene from a virus pathogenic to that plant confers protection to the plant against this or closely related viruses. To expand our understanding of the breadth of protection conferred by CP genes, transgenic tobacco plants were produced that ...
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    Biotech Changing Agribusiness (1989)
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    Nature biotechnology 7 (1989), S. 219-219 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] SAN FRANCISCO—Biotechnology stands poised to catalyze a major change in the structure of worldwide agribusiness. According to John M. Hardinger, director of biotechnology at E. I. du Pont de Nemours' (Wilmington, DE) agricultural products department, the increasing application of molecular ...
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    Biotherapy: A New Dimension in Cancer Treatment (1989)
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    Nature biotechnology 7 (1989), S. 231-240 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The biomedical community has spent the last 40 years searching for new and effective ways to treat cancer. During this time, research scientists have made great strides in understanding the nature of neoplastic cell transformation and the body's reaction to it. From this, new ways to treat cancer ...
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    Catching the Fever, Faster (1989)
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    Nature biotechnology 7 (1989), S. 1211-1211 
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    Notes: [Auszug] On Wednesday morning, with the news that Jordi Casals was going downhill more rapidly than ever, a major meeting was called in Room 608 of the library of the Yale arbovirus laboratory. Just before the meeting, Wil Downs put through a phone call to his colleague, Dr. Karl Johnson, a leading ...
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    Conflict of Interest (1989)
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    Nature biotechnology 7 (1989), S. 1207-1207 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Put your books under your seats and take out a pencil. We're going to start today's class with a role-playing quiz on political science…or is it science policy? In any case, the objective is to locate those instances in which the declared policies of governments seem to conflict with the ...
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    1990 Funding Uncertain for NIH Effort (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1222-1222 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] WASHINGTON, D.C.—The National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH, Bethesda, MD) recently awarded the first postdoctoral fellowships and predoctoral training grants in the new Chiles biotechnology training program. The program's future ...
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    Announcements (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 302-303 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] MARCH MEETINGS Mar. 27–Apr. 3. Molecular Mechanisms in DNA Replication and Recombination. Keystone, CO. Info: UCLA Symposia, 2032 Armacost Ave., Los Angeles, CA 90025. Mar. 28–30. AgBiotech '89. Arlington, VA. Info: Sharon Green, Conference Management Corporation, 200 Connecticut ...
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    DNA Probes Revisited (1989)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 7 (1989), S. 1227-1227 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] SAN DIEGO, Calif.—Every year about this time scientists and analysts alike try to get a feel for the size of the DNA probes market. Today's fortune tellers may be a bit more reliable than their predecessors, their vision tempered by the reality of 1988's $25-million DNA probes market ...
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