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  • Books  (87)
  • bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology  (80)
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  • Books  (87)
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  • 1
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-07
    Description: This book offers a comprehensive overview of recent developments in the field of obesity. The chapters are authored by prominent scholars in the field with direct knowledge, through practice and research, of the real-world problems associated with obesity. Chapters address such topics as obesity in children, stigmatization of people with obesity, metabolic effects of obesity, recent advances in pharmacology and surgical interventions for obesity, and more.
    Keywords: inflammation ; oxidative stress ; energy ; metabolism ; neurodegeneration ; leptin ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 2
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-07
    Description: Beta Cells in Health and Disease presents the latest information on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This book includes chapters on a variety of topics, including the importance and the biology of insulin hormone, pancreatic beta cell dysfunction in type 1 diabetes, the biological importance of physical activity in managing type 1 diabetes, the use of stem cell therapy for the treatment of diabetes, the role of microRNAs in modulating beta cell function, and more.
    Keywords: Insulin ; Hyperglycemia ; Beta-Cells ; Diabetes Mellitus ; Oxidative Stress ; Type 1 Diabetes ; ER Stress ; Reactive Oxygen Species ; Sex Steroids ; GLP-1 ; Insulin Secretion ; Hypogonadism ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 3
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-07
    Description: The book presents an in-depth exploration of adrenal anatomy, physiology, and pathology, authored by a multidisciplinary team of international experts, providing an exposition of the current state of knowledge in the field of adrenal diseases and offering insights into the evolution of their management. The addressed pathologies are intricate and diverse, encompassing conditions such as Cushing’s disease, primary aldosteronism, pheochromocytoma, and congenital adrenal hyperplasia. Each pathology chapter delves into etiopathogenic aspects, clinical evidence, and therapeutic recommendations. This publication caters equally to endocrinologists and professionals from various medical disciplines, serving as a valuable resource for information on the adrenal gland from both a physiological and pathological perspective.
    Keywords: bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 4
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-07
    Description: Welcome to the world of Oxytocin and Social Function, an in-depth exploration of the powerful role of this neuropeptide in shaping our social behaviors and interactions. The book delves into the rich and complex relationship between oxytocin and our social functions. Featuring contributions from leading experts in the field, this book offers a comprehensive understanding of oxytocin’s role in our social lives. It goes beyond the laboratory to explore the hormone’s potential in real-world applications. The book also highlights recent research on oxytocin’s role in enhancing empathy, reducing stress, and promoting overall well-being. With this book, readers will gain a deeper understanding of the intricate workings of oxytocin and how it shapes our social behaviors and relationships. Oxytocin and Social Function is a must-read for anyone interested in human behavior, psychology, neuroscience, or the ever-growing field of oxytocin research. Turn the page and embark on a captivating journey into the hidden potentials of oxytocin and its transformative effects on our social function.
    Keywords: bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 5
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-07
    Description: This book, The Pituitary Gland - An Overview of Pathophysiology and Current Management Techniques, provides a comprehensive overview of key pituitary diseases and their profound impact across a diverse spectrum of medical disciplines. It explores acromegaly management, presenting the latest treatment guidelines and precision-based management techniques. It also discusses neurosurgical operative techniques to ensure adequate decompression of the optic chiasm, providing useful information for both surgical and non-surgical practitioners. The book also examines the critical topic of fertility preservation. Finally, it offers a complementary perspective on pituitary gland stimulation and activation. This book promises an engaging and informative journey for all curious minds in the medical and academic spheres.
    Keywords: Acromegaly ; Hypothyroidism ; Hyperthyroidism ; Growth Hormone ; Molecular Genetics ; Stem Cells ; Receptors ; Co-localization ; Pituitary Dysfunction ; MR Features ; Deep Learning ; Radiomics ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 6
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-07
    Description: Maintaining an ideal weight throughout life is the most beneficial thing someone can do for their body. A healthy body and ideal weight can be achieved with proper nutrition and lifestyle, starting from childhood and even infancy. Therefore, it is important for those raising children to be conscious of this issue and to be good role models and guides for their children by exhibiting the healthiest lifestyle habits. We know that it is almost impossible to remove excess fat tissue acquired during childhood from the body at later ages. Body fat accumulation is usually evaluated by body mass index (BMI), which is calculated using weight and height proportions. BMI is an effective and useful tool for both people and healthcare professionals to track body fat percentage. However, when monitoring body fat with BMI special adjustments need to be made in children, the elderly, different genders, and individuals with high muscle mass. This book provides a comprehensive overview of BMI as a screening measure.
    Keywords: bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 7
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Green computing involves developing, designing, engineering, producing, using, and disposing of computing modules and devices to reduce environmental hazards and pollution. Green computing technologies are crucial for protecting the planet from environmental hazards and pollution. This book presents new subjects and innovations in green computing technologies and in green computing and electronics industries. Chapters address such topics as green wearable sensors, variable renewable energy, managing energy consumption using the Internet of Things (IoT) and big data, using forest waste to produce biofuel and biodiesel, green computing in ophthalmological practice, and much more.
    Keywords: agriculture ; renewable energy ; biodiversity ; energy ; big data ; iot ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQD Environmental monitoring
    Language: English
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  • 8
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Solar energy is a significant renewable energy source that is abundant and environmentally friendly. Solar PV Panels – Recent Advances and Future Prospects provides a comprehensive overview of solar photovoltaic (PV) panels for direct electric power production. Chapters address such topics as fundamentals of solar PV panels; modeling, simulations, optimization, and economics of solar panels; solar panels testing; semiconductor materials for solar cells and panels; solar PV applications and policies; and solar PV and battery storage sizing for stand-alone and grid-connected applications.
    Keywords: solar cells ; renewable energy ; energy ; cfd ; 2d materials ; solar energy ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THV Alternative and renewable energy sources and technology
    Language: English
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  • 9
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Type 1 diabetes is a complex and challenging health condition that affects up to 2% percent of the global population. This book provides a comprehensive overview of this chronic clinical entity, focusing on causes, development, and management. It includes nine chapters that address such topics as managing diabetes using insulin and medical devices such as pens and pumps, how lifestyle affects diabetes, biomarkers for the disease, and much more.
    Keywords: insulin ; type 1 diabetes mellitus ; artificial intelligence ; biomarkers ; apoptosis ; diabetes mellitus ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 10
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: Melatonin, the pineal neurohormone, is a pleiotropic molecule acting in the center of the integrative molecular mechanisms of the organism, based on interconnections of the regulatory systems: neural, endocrine, immune, and genetic, conveying into the uniqueness of human architecture. This book provides a systematic and updated overview of melatonin biochemical mechanisms of action, pharmacological features, and clinical uses, clutching the subject with complete details of pharmaceutical formulations designed for different routes of administration and different health issues, aiming at optimal melatonin bioavailability when therapeutically delivered. The book addresses a broad range of audiences, from healthcare professionals, medically and pharmaceutically based, to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge of the physiological and pathological implications of melatonin and its metabolites.
    Keywords: tryptophan, oxidative stress, antioxidant, epilepsy, autism, anti-inflammatory ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 11
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: This is a small book containing various aspects of thyroid gland disorders. Congenital hypothyroidism chapter emphasizes early diagnosis in prevention of irreparable damage to growth and brain of infants. Role of nuclear medicine in diagnosis and treatment is outlined. Last few chapters deal with congenital hypothyroidism, thyroid carcinoma, its diagnosis, treatment and preservation of posterior parathyroid gland during thyroid surgery. The purpose of the book is to disseminate knowledge on thyroid diseases. It will be a good reference book both for students of medicine and general practitioners.
    Keywords: surgery, ultrasound, hypothyroidism, congenital, thyrotoxicosis, thyroidectomy ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 12
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    IntechOpen | IntechOpen
    Publication Date: 2023-02-15
    Description: Melatonin is a powerful hormone and antioxidant with numerous effects on metabolism and human health. Available as a dietary supplement for many years, it is one of the most popular over-the-counter alternative medicines available. Featuring contributions from researchers investigating the role of melatonin in various diseases and physiological conditions, this comprehensive book offers a wide range of expert reviews on the synthesis, regulation, and physiological effects of melatonin as well as its role in various diseases.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 13
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Malnutrition is the specific condition produced by the intake of too few macronutrients, too many macronutrients (obesity), or inordinate amounts of inappropriate substances such as alcohol. Globally, malnutrition is a major nutritional disorder, especially in developing economies. Poor dietary habits and imbalanced nutrient intake result in adverse consequences on normal body functionality. This book highlights the major causes of malnutrition and how to overcome this problem. Chapters address such topics as energy metabolism and balance, diagnosis of malnutrition, negative effects of malnutrition, sugar and its impact on health, malnutrition in the elderly and children, and much more.
    Keywords: public health ; undernutrition ; cancer ; inflammation ; energy ; metabolism ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine::MBNH Personal & public health::MBNH3 Dietetics & nutrition
    Language: English
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  • 14
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Estrogen - Recent Advances explores the role of estrogen in many disease processes and organ systems. Chapters discuss G-protein estrogen receptor signaling and estrogen’s effect on the oral cavity, olfactory mucosae, and the prostate. The book presents cutting-edge research and developments in the field. Understanding the many effects estrogen has on the body will help the reader better understand disease processes and provide a framework for future discoveries.
    Keywords: alveolar bone ; oral cavity ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 15
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: The Renin-Angiotensin Aldosterone System (RAAS) plays an important role not only in salt and water homeostasis but also in the cardiovascular system, the kidney, and the brain. While several volumes address different aspects of the RAAS function, this book provides cutting-edge information on the pathogenesis of various disorders related to RAAS overactivation. It also presents unique aspects of RAAS functioning that have not been sufficiently described in the literature. Topics covered include assessment of hypoaldosteronism in infancy, RASS and cognitive decline, and the role of RAAS in the pathogenesis of COVID-19. Written by experts in the field in an easy-to-follow and illustrated format, this volume will benefit students and practitioners, as well as clinical and basic science investigators alike.
    Keywords: covid-19, hypertension, ace2, oxidative stress, diabetes, alzheimer’s disease ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 16
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.
    Keywords: alzheimer’s disease, neuroprotection, estrogens, testosterone, androgens, progesterone ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 17
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: The book presents a qualitative and quantitative approach to understand, manage and enforce the integration of insulin into diabetes mellitus. Utilizing a sound theoretical and practical foundation and illustrating procedural techniques through scientific examples, the book bridges the gap between insulin and diabetes mellitus management. Detailed procedures have been omitted because of the variety of equipment and commercial kits used in today's clinical laboratories.
    Keywords: insulin resistance, biomarkers, obesity, diabetes, cytokines, metabolic syndrome ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 18
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Parathyroid glands regulate the levels of calcium, phosphorus, magnesium, and vitamin D in the human body via the secretion of parathyroid hormone (PTH). There are several disorders that can affect the parathyroid glands. These can be genetic, idiopathic, or iatrogenic and can cause poor quality of life, depression, and anxiety. This book discusses parathyroid glands, the importance of proper detection of PTH, parathyroid gland pathophysiology, bone dynamics and dentistry, and genetic diseases of the parathyroid glands.
    Keywords: hyperparathyroidism ; dentistry ; parathyroid hormone ; hypoparathyroidism ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 19
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: Aortic aneurysms are very silent, insidious, and sudden complicated pathologies with high incidence of sudden death. The aorta has several different parts, which are affected by aneurysmal pathology independently and separately or conjointly. Preventive medicine and determinative genetic heritage are the first steps during diagnosis and precaution. Preventive screening of the general population seems the best way for diagnosing early asymptomatic aneurysms with increased health cost. Because sudden death is the first symptom of aortic aneurysms, early interventional treatment is essential to protect fatal complications. In spite of open surgical repair which is the standard procedure, isolated or hybrid endovascular approaches are used widespread in the last decade due to reduction of procedural complications. This book is composed of the main topics on aortic aneurysms and surgical treatments to extend scientific and therapeutic perspective and vision of cardiac teams.
    Keywords: inflammation, gender, cfd, macrophage, hemodynamics, computational fluid dynamics (cfd) ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 20
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: This Edited Volume “Nanogenerators and Self-Powered Systems” is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of nanotechnology and nanomaterials. The book comprises single chapters authored by various researchers and edited by an expert active in harnessing the ubiquitously available biomechanical energies to power portable electronics research area. All chapters are complete in themselves but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on nanotechnology and nanomaterials and opening new possible research paths for further novel developments.
    Keywords: energy ; sensors ; mems ; solar energy ; solar cells ; photovoltaic ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THV Alternative and renewable energy sources and technology
    Language: English
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  • 21
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    IntechOpen | IntechOpen
    Publication Date: 2023-02-15
    Description: Over the last decades, the growing prevalence of insulin resistance has dramatically contributed to the global epidemic of metabolic syndrome, obesity, type 2 diabetes mellitus, and cardiovascular disease. Therefore, there is an unmet need for novel nutritional and pharmacological strategies aimed to prevent or treat insulin resistance and its related comorbidities. This book presents a comprehensive overview of the pathophysiology and clinical consequences of insulin resistance in different settings, describing novel diagnostic biomarkers and molecular targets of this condition.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 22
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.
    Keywords: oxidative stress, heart failure, hypertension, stress, inflammation, obesity ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 23
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Carbon Nanotubes - Recent Advances, New Perspectives and Potential Applications covers all the important nanotechnological aspects of carbon materials, including their growth and characterization, processing and fabrication, development and potential applications. Recent developments, innovative preparation methods and promising new frontiers around this advanced nanotechnology are reviewed under the editorship of an internationally renowned scientist. This book will be useful to a diverse range of readers and will be important for research organizations, government research centers, academic libraries, and those involved in the research and development of carbon materials.
    Keywords: nanoparticles ; nanocomposites ; energy ; wastewater treatment ; nanofibers ; conductivity ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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  • 24
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Corals have thrived on the bottom of the ocean for millions of years. These fascinating animals are currently forced to cope with the rapid changes caused by humans to avoid extinction. How are corals changing their way of processing energy from different sources? What do we know about the corals living in the unseen depths of certain seamounts? What is the impact of oil spills and what can we do? How are coral reefs all over the world to be restored? What is the socioeconomic importance of these habitats, and what do we gain or lose with their survival or their demise? By involving scientists and conservationists from different areas of the world, this book answers these and other questions about corals, the habitat they form, and the influence that we have on them.
    Keywords: climate change ; conservation ; energy ; bioremediation ; metabolism ; probiotics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSP Hydrobiology::PSPM Marine biology
    Language: English
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  • 25
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: Diabetes mellitus is a metabolic disease characterized by chronic high blood glucose levels. Of the various types of diabetes, type 2 diabetes is increasing in prevalence due to obesity, aging, sedentarism, and other factors. This book presents a novel approach to preventing and treating type 2 diabetes. Chapters cover such topics as diagnosis, pathogenesis, management, lifestyle and nutritional intervention, and systems to support early diagnosis and prevention of prediabetes.
    Keywords: diabetes mellitus, insulin resistance, metabolic syndrome, type 2 diabetes mellitus, oxidative stress, machine learning ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 26
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: The World Health Organization estimated that each year there are more than 13 million deaths caused by environmental causes. Exposure to endocrine disrupting chemicals (EDCs) during development may cause long-term health outcomes. This book, Endocrine Disruptors, includes eight chapters that illustrate potential endocrine-disrupting activities in water, sediments, crops, animals, and humans. This book assesses the relationship between the EDCs and development, reproduction, or obesity. Finally, detection of the levels of EDCs by autobioluminescent cellular bioreporters is discussed. Scientists, physicians, neuroendocrinologists, neurotoxicologists, and lay readers who have engaged in EDC studies or practice will discover that this book offers insight into all areas of EDC research.
    Keywords: phthalates, reproduction, estrogen, sediments, bisphenol a, water pollution ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 27
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    IntechOpen | IntechOpen
    Publication Date: 2023-02-15
    Description: Management of hypoglycemia in diabetes mellitus is a landmark achievement, especially in patients who take insulin. This book provides a comprehensive overview of hypoglycemia, including its pathophysiology, causes, clinical manifestations, management, and screening. It presents recent findings and research in the field and discusses new advancements in hypoglycemic control, including recently developed point-of-care devices for the home and the clinic.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 28
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: Corticosteroids are mainly used to reduce inflammation and suppress the immune system. Corticosteroids will only be prescribed if the potential benefits of treatment outweigh the risks. They will also be prescribed at the lowest effective dose for the shortest possible time. This book will strive to highlight the importance of corticosteroids, to focus on minimizing side effects, to monitor and sensitize the population on the potential adverse effects of misuse, to provide additional knowledge about the design and development of new drug delivery systems loaded with corticosteroids potentially useful in the treatment of chronic inflammatory-based diseases, and to reduce inflammation and affect the immune system. The major objective of this book will be to present the information in a lucid, condensed, and cohesive form and to specially cater to the needs of readers in medicine and pharmacy.
    Keywords: glucocorticoids, cortisol, epigenetics, stress, pathophysiology, asthma ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 29
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    IntechOpen | IntechOpen
    Publication Date: 2023-02-15
    Description: The physiological or pathological variations in the amount or mass of each component of body weight can lead to an increase or a decrease in total body weight, with a potential risk of increased morbidity and mortality. This book presents an overview of current knowledge about different types of body weight changes, with a special emphasis on obesity.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 30
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: Exploring the contractile activity of smooth muscle segments isolated from various organs of healthy animals and animals with experimentally induced diabetes, she obtained original data about angiotensin II-induced force and time parameters. For the first time, she established the effect of ghrelin on angiotensin II-provoked contraction of the urinary bladder. Original data on the role of both types of angiotensin receptors for the contractile activity of the various segments of the gastrointestinal tract and bladder were obtained. By applying specific software for force and time parameter analysis, the contribution of different types of angiotensin receptors on muscle contractility has been shown. The new methodology was used to analyze the data obtained during the registration of smooth muscle relaxation activity, which allows the determination of not only the magnitude of the mechanical response but also the parameters related to the time and speed of the contractions. Plasma renin activity models have been developed using mathematical approaches to predict the effect of different drug doses on the behavior of the system.
    Keywords: hypertension, biomarkers, heart failure, atherosclerosis, reactive oxygen species, chronic kidney disease ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 31
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: Adipose tissue is a specialized connective tissue which, depending on type, plays different and significant roles in the human body: protects against environmental factors, stores lipids and triacylglycerol, synthesizes fatty acids and is involved in the process of thermogenesis. It is also a major secretory organ and highly active metabolic tissue. It secretes, for example, cholesterol, retinol, steroid hormones, prostaglandins and proteins known as "adipokines". Some of these molecules may be associated with pathologies such as obesity and insulin resistance. In humans, there are two main sites of adipose tissue accumulation: visceral and subcutaneous. Obesity is a worldwide health problem. This book also discusses a series of up-to-date topics about this pathology.
    Keywords: inflammation, obesity, diabetes, adipogenesis, adipocyte, cancer ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 32
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: Oxytocin is a nonapeptide hormone with a central role in the regulation of parturition and lactation. Oxytocin receptors can be found in many tissues in humans. Oxytocin exerts a direct as well as an indirect effect on metabolism and energy balance. Considering the positive effects of oxytocin on the brain and the reproductive, immune, and autonomic nervous systems, it shows promise as a future treatment agent for anxiety, autism, personality disorders, and neurodegenerative disorders. This book focuses on oxytocin and health from the aspects of molecular and structure activity, physiological and pathological functions, and clinical applications.
    Keywords: obesity, inflammation, diabetes, pregnancy, nanomaterials, drug delivery ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2023-02-15
    Description: Lifestyle-related diseases are caused by an unbalanced diet and irregular, undesirable lifestyle, leading to a condition called metabolic syndrome. Rather like dominoes falling, these diseases develop one after another. Owing to changes in dietary habits and working environments, the incidence of lifestyle-related diseases, obesity, and metabolic syndrome is increasing globally, resulting in a serious social problem that needs to be solved. This book deals with recent studies on lifestyle-related diseases and metabolic syndrome, and the following three topics are discussed: (1) characteristics of metabolic syndrome and lifestyle-related diseases; (2) the relationship between metabolic syndrome and several diseases; and (3) effective interventions to prevent lifestyle-related diseases. This book provides new ideas for the treatment and prevention of metabolic syndrome and lifestyle-related diseases.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 34
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    Publication Date: 2023-12-01
    Description: Saliva is a complex fluid that maintains oral health and has many physiological functions. It is a noninvasive diagnostic fluid as well. Lately, salivary diagnostics has proven its potential to reach clinical practice in the near future for the early detection, diagnosis, and monitoring of various diseases. Salivary Glands - New Approaches in Diagnostics and Treatment is a comprehensive reference, which brings together information on salivary secretion and its disorders, the novel salivary diagnostic methods for numerous diseases, and new techniques in the treatment of salivary diseases. This book contains information for a diverse audience, including dentists, oral biologists, experimental biologists, molecular biologists, oncologists, radiologists, oral and maxillofacial surgeons, and otorhinolaryngologists.
    Keywords: etiology, biomarkers, mass spectrometry, proteomics, liquid biopsy, chromatography ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 35
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: The field of endocrinology and metabolism represents a complex and multifaceted specialty in medicine that may be affected by different factors. This book presents an overview of several endocrine-disrupting chemicals, especially those affecting the reproductive system and adipose tissue. It also discusses the endocrine and metabolic impacts of the COVID-19 pandemic and the pathogenesis of lipedema.
    Keywords: covid-19, inflammation, obesity, pandemic, gut microbiota, reproduction ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 36
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Growth Hormone - Impact and Insights in Human Beings presents aspects of the importance of growth hormone and the complexity of its actions, from biochemistry to its relevance to the growth of an individual. The gene family that generates isoforms of the GH, as well as the pituitary growth hormone secretion and signaling pathways, are discussed. Interventions to prevent disease or increase the serum concentration of growth hormone, such as physical exercises, are also explored. This information aims to contribute to understanding the management of clinical conditions involving the growth hormone and to support readers in decision-making.
    Keywords: obesity ; metabolism ; hypothalamus ; igf-1 ; carbohydrate ; exercise ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 37
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    Publication Date: 2023-09-05
    Description: Diabetic foot ulcers are a common complication of diabetes, and their treatment depends on the underlying causes. This book provides a basic understanding of diabetic foot ulcers (DFUs), including their pathophysiology, assessment, and treatment. Chapters present recent research findings with a focus on advancements in the treatment of DFUs, such as point-of-care devices for use at home and in the clinic.
    Keywords: diabetes ; inflammation ; machine learning ; epigenetics ; diabetes mellitus ; quality of life ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 38
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Hyperthyroidism is a condition caused by physiological, biological, and clinical findings that cause hypermetabolism as a result of the excessive elevation of thyroid hormones in the blood and the surrounding tissues under the influence of high levels of hormones. There is a general acceleration in metabolism. There are a wide variety of methods in the treatment of hyperthyroidism, such as antithyroid drugs, lithium carbonate, radioactive iodine, and dexamethasone. This comprehensive book, with contributions from various researchers on thyroid hormones and hyperthyroidism, offers a wide range of expert reviews on the release of thyroid hormones, their physiological effects, and the occurrence of hyperthyroidism as well as its types, effects, and treatment options.
    Keywords: graves’ disease ; radioactive iodine ; thyrotoxicosis ; surgery ; infertility ; blood pressure ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 39
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: Neurodegenerative diseases are severe, rapidly developing, and currently incurable conditions that result in progressive degeneration and the death of neurons. This causes dementia, movement problems, and essentially loss of personal identity. Amyloids attempts to answer the following questions: (1) why do we develop these severe neurodegenerative diseases? (2) what histological and physiological changes are observed upon development and progression of these diseases? and (3) how can we treat amyloid-associated diseases?
    Keywords: inflammation, alzheimer’s disease, dementia, diabetes mellitus, insulin resistance, polymer ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 40
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    Publication Date: 2023-09-05
    Description: Solid Waste and Landfills Management - Recent Advances outlines the fundamental ideas and most recent developments for managing solid waste in an environmentally responsible manner. Globally, the quantity of solid trash is increasing, but its environmental impact is also a concern, especially with the advent of elements that are detrimental to ecosystems. This book examines all aspects of solid waste from a global perspective, including waste minimization, waste as a resource, proper disposal, and efficient systems promoted by sound public policy. It includes eight chapters written by eminent specialists that examine the essential topics to be considered during the various phases of a waste management program. Among the topics covered in this book are public policies focusing on reducing waste at its source, recycling, and minimizing disposal amounts; technologies for treating and recycling solid waste; safe, efficient treatment and disposal of hazardous and other special wastes; development and maintenance of engineered landfills and landfill mining; and legal frameworks and the use of life-cycle assessment as a tool for the waste management industry. This book is an indispensable resource for municipal engineers, environmental managers, researchers, students, policymakers, and planners interested in social and technological challenges connected to sustainable solid waste management.
    Keywords: environment ; energy ; biofuels ; ethanol ; recycling ; waste management ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNH Waste management
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  • 41
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    Publication Date: 2023-12-01
    Description: Testosterone regulates the physiological functions and morphology of biological organisms including humans at multiple stages of development. Understanding what is currently known about testosterone is important for specialists in many branches of science, including internal medicine, veterinary medicine, sports science, economics, cognitive neuroscience, and psychology. This book describes what is currently known about the androgenic function and its underlying mechanisms as well as reviews ethical and safety issues surrounding the clinical and practical application of achievements in testosterone research.
    Keywords: inflammation, mass spectrometry, adverse effects, androgens, lung, cytochrome p450 ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 42
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    Publication Date: 2023-12-01
    Description: This book is a very provocative addition to the literature on pituitary diseases, it delivers lots of stimulating work and offers rich scientific material for readers in different disciplines. The book provides a detailed update on current diagnostic and therapeutic techniques useful in the management of pituitary diseases. Microsurgical surgery, medical treatment, and radiotherapy has been used in the last decades; however, the prediction of post-medical, postsurgical treatment, and post-radiotherapy treatment is still controversial. The book contents reflect the multidisciplinary approach needed for patients with pituitary diseases with contribution from neurosurgeons, endocrinologists, neurologists, radiologists, ophthalmologists, pathologists, and radiation oncologists. The book focuses on some pituitary diseases especially the most controversial subjects in the medical and surgical treatment such as dedicated surgical technique by huge pituitary adenoma, the management of celiac patients with growth failure, pituitary apoplexy, neuro ophthalmology findings in pituitary disease, and the immunohistochemical studies in pituitary adenomas, moreover there is a special chapter about transoral robotic surgery (TORS) with the da Vinci system.
    Keywords: celiac disease, pituitary adenoma, growth hormone deficiency, short stature, craniopharyngioma ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 43
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    Publication Date: 2023-12-01
    Description: Rates of diabetes are increasing worldwide with cases spreading to various regions of both developing and developed countries, increasing the risk of various organ diseases. Nutritional interventions such as low-calorie, low-sugar diets have now become critical for combatting the disease. Written by experts from around the globe, this book examines the risks and benefits of sugar intake and the critical role of functional foods in treating diabetes. The chapters provide information to control sugar intake and to prevent the induction of organ disease in diabetic individuals.
    Keywords: obesity, glucose metabolism, cancer, inflammation, oxidative stress, pregnancy ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 44
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    Publication Date: 2023-12-01
    Description: Diabetes is a complex, progressive disease, which is accompanied by several complications. It is listed among the most common endocrine disorders and a global metabolic epidemic disease. This book focuses on the recent progress in diabetes research worldwide. It has been written by extensively acknowledged experts, with each chapter providing a unique data on developing features of diabetes. It covers the interactions between diabetes and several disorders. Also, it suggests some treatments for this disease offering us hope in prevention and successful improvement.
    Keywords: oxidative stress, aging, diabetes mellitus, cancer, inflammation, obesity ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 45
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: This book is the second in a series of two, featuring the Adiposity - Omics and Molecular Understanding, serving as an introduction to modern views on how the adipocytes are reciprocally interacting with organ systems in order to explain the biology of the body's fat cells and how they are integrated with other organ systems, like muscle cells and the liver, in order to control the lipid metabolism in our bodies, to finally preserve a positive balance between white and brown/beige adipocyte tissues (WAT and BAT). The understanding of the "omics" of obesity will therefore enable clinicians and researchers to better pursue the untoward incidents of metabolic deviations from a defined and health-bringing homeostasis, with fully responding WAT and BAT, being able to preserve a healthy balance between fat-producing and fat-metabolizing tissues for the benefit of the host, and thus longevity (optimal health with healthy, well-functioning organ systems) throughout a lifetime.
    Keywords: inflammation, obesity, diabetes, cytokines, pregnancy, hypoxia ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 46
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    Publication Date: 2022-07-27
    Description: Hypothyroidism is an endocrine disorder commonly caused by Hashimoto’s disease. Nowadays, autoimmune diseases appear to be on the rise. As such, there is renewed interest in hypothyroidism. This book presents a comprehensive overview of the disorder with chapters on etiology and pathogenesis, precision medicine tools for detection, diagnosis and treatment, the morphology of the thyroid gland, the effect of hypothyroidism on various organ systems, and much more.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    Publication Date: 2022-01-31
    Description: We are truly in an era of change not only in terms of technology but in the type of patient we are caring for. That is why I feel this book is exciting in that it presents the team approach to the transplant patient. I am confident that the pioneers of cardiac transplantation would be pleased with our response to challenges in healthcare today and be pleased with the final product.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 48
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    Publication Date: 2022-01-31
    Description: Hypothyroidism is the most common thyroid disorder. It can cause a variety of changes in women's menstrual periods, reduce their chances of becoming pregnant, as well as affect both the course of pregnancy and the neuropsychological development of babies. During pregnancy there is a substantially increased need for thyroid hormones and a substantial risk that a previously unnoticed, subclinical or latent hypothyroidism will turn into overt hypothyroidism. The thyroid inflammation caused by the patient's own immune system may form autoimmune thyroiditis (Hashimoto's thyroiditis). Congenital hypothyroidism (CH) occurs in approximately 1:2,000 to 1:4,000 newborns. Nearly all of the developed world countries currently practice newborn screening to detect and treat congenital hypothyroidism in the first weeks of life. "A New Look at Hypothyroidism" contains many important specifications and innovations for endocrine practice.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 49
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    Publication Date: 2022-01-31
    Description: Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed insulin secretion in both healthy individuals and in patients with type 2 diabetes. Because of the risk associated with progression from insulin resistance to diabetes and cardiovascular complications increases along a continuum, we included several chapters on the damage of endothelial cells in type 2 diabetes and genetic influences on endothelial cell dysfunction. Cardiovascular complications occur at a much lower glucose levels, thus a review on the oral glucose tolerance test compared to other methods was included. The medical conditions associated with type 2 diabetes such as pancreatic cancer, sarcopenia and sleep disordered breathing with diabetes were also discussed. The book concludes with several chapters on the treatments for this disease offering us hope in prevention and successful alleviation of the co-morbidities associated with obesity and type 2 diabetes.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 50
    Publication Date: 2022-01-31
    Description: Type 2 diabetes "mellitus" affects nearly 120 million persons worldwide- and according to the World Health Organization this number is expected to double by the year 2030. Owing to a rapidly increasing disease prevalence, the medical, social and economic burdens associated with the microvascular and macrovascular complications of type 2 diabetes are likely to increase dramatically in the coming decades. In this volume, leading contributors to the field review the pathogenesis, treatment and management of type 2 diabetes and its complications. They provide invaluable insight and share their discoveries about potentially important new techniques for the diagnosis, treatment and prevention of diabetic complications.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    Publication Date: 2022-01-31
    Description: This book is a collection of essays and papers from around the world, written by surgeons who look after patients of all ages with abdominal pain, many of whom have appendicitis. All general surgeons maintain a fascination with this important condition because it is so common and yet so easy to miss. All surgeons have a view on the literature and any gathering of surgeons embraces a spectrum of opinion on management options. Many aspects of the disease and its presentation and management remain controversial. This book does not answer those controversies, but should prove food for thought. The reflections of these surgeons are presented in many cases with novel data. The chapters encourage us to consider new epidemiological views and explore clinical scoring systems and the literature on imaging. Appendicitis is discussed in patients of all ages and in all manner of presentations.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 52
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    Publication Date: 2022-01-31
    Description: In this book, several important points regarding Crohn's disease are discussed. In the first section, we focus on etiopathogeny of Crohn's disease and the recent advances in our overall understanding of the disease - specifically, the role of the gut epithelium, alterations of the epithelial crypts, and the roles of the different cytokines in the pathophysiology of Crohn's disease. In the second section, a diagnosis of Crohn's disease is discussed. Another particular area of focus is in the diagnosis of intestinal tuberculosis, and the role of mycobacterium avium in Crohn's disease. In the third and final section, the management of Crohn's disease is discussed, with a focus on recent evidence-based medicine recommendations.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 53
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    Publication Date: 2022-01-31
    Description: Currently, aortic stenosis is the most frequent heart valve disease in developed countries and its prevalence increases with the aging of the population. Affecting 3-5 percent of persons older than 65 years of age, it makes a large personal and economical impact. The increasing number of elderly patients with aortic stenosis brings advances in all medical specialties dealing with this clinical entity. Patients previously considered too old or ill are now indicated for aortic valve replacement procedures. This book tries to cover current issues of aortic valve stenosis management with stress on new trends in diagnostics and treatment.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 54
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    Publication Date: 2022-01-31
    Description: Acute Pancreatitis (AP) in approximately 80% of cases, occurs as a secondary complication related to gallstone disease and alcohol misuse. However there are several other different causes that produce it such as metabolism, genetics, autoimmunity, post-ERCP, and trauma for example... This disease is commonly associated with the sudden onset of upper abdominal pain that is usually severe enough to warrant the patient seeking urgent medical attention. Overall, 10-25% of AP episodes are classified as severe. This leads to an associated mortality rate of 7-30% that has not changed in recent years. Treatment is conservative and generally performed by experienced teams often in ICUs. Although most cases of acute pancreatitis are uncomplicated and resolve spontaneously, the presence of complications has a significant prognostic importance. Necrosis, hemorrhage, and infection convey up to 25%, 50%, and 80% mortality, respectively. Other complications such as pseudocyst formation, pseudo-aneurysm formation, or venous thrombosis, increase morbidity and mortality to a lesser degree. The presence of pancreatic infection must be avoided.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    Publication Date: 2022-01-31
    Description: Adipocytes are important in the body for maintaining proper energy balance by storing excess energy as triglycerides. However, efforts of the last decade have identified several molecules that are secreted from adipocytes, such as leptin, which are involved in signaling between tissues and organs. These adipokines are important in overall regulation of energy metabolism and can regulate body composition as well as glucose homeostasis. Excess lipid storage in tissues other than adipose can result in development of diabetes and nonalcoholic fatty liver disease (NAFLD). In this book we review the role of adipocytes in development of insulin resistance, type 2 diabetes and NAFLD. Because type 2 diabetes has been suggested to be a disease of inflammation we included several chapters on the mechanism of inflammation modulating organ injury. Finally, we conclude with a review on exercise and nutrient regulation for the treatment of type 2 diabetes and its co-morbidities.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 56
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    Publication Date: 2022-01-31
    Description: Chronic pancreatitis is a disease of diverse etiologies in which pain can be devastating, severely impairing quality of life, and treatment is a challenge. This book covers cutting edge basic science research and clinical diagnosis and treatment issues in chronic pancreatitis. Basic science chapters include studies on amelioration of chronic pancreatitis in rats by bone marrow derived mesenchymal cells; on gene therapy using HSV-Enkephalin to reduce fibrosis, inflammation and pain in a rats; and on pancreatic acinar and island neogenesis according to vascular and matrix dynamics of human and animal tissue. In regard to the clinical aspects, the role of endoscopic ultrasound in detecting the changes of chronic pancreatitis are addressed as well as the endoscopic treatment via duct drainage procedures or stone removal. Finally, the surgical options for chronic pancreatitis (there are well over 20 procedures) are extensively discussed, with a final chapter on total pancreatectomy and islet autotransplant to definitively remove the root cause of the pain with preservation of endocrine function. This book will be valued by basic scientists and clinicians striving to understand the mechanisms of pain in chronic pancreatitis and the treatment options in patients so afflicted.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    Publication Date: 2022-01-31
    Description: Over the last decade, it is becoming increasingly clear that diabetes mellitus is a global epidemic. The influence of diabetes is most readily apparent in its manifestation in foot complications across cultures and continents. In this unique collaboration of global specialists, we examine the explosion of foot disease in locations that must quickly grapple with both mobilizing medical expertise and shaping public policy to best prevent and treat these serious complications. In other areas of the world where diabetic foot complications have unfortunately been all too common, diagnostic testing and advanced treatments have been developed in response. The bulk of this book is devoted to examining the newest developments in basic and clinical research on the diabetic foot. It is hoped that as our understanding of the pathophysiologic process expands, the devastating impact of diabetic foot complications can be minimized on a global scale.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 58
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    Publication Date: 2022-01-31
    Description: Liver biopsy is recommended as the gold standard method to determine diagnosis, fibrosis staging, prognosis and therapeutic indications in patients with chronic liver disease. However, liver biopsy is an invasive procedure with a risk of complications which can be serious. This book provides the management of the complications in liver biopsy. Additionally, this book provides also the references for the new technology of liver biopsy including the non-invasive elastography, imaging methods and blood panels which could be the alternatives to liver biopsy. The non-invasive methods, especially the elastography, which is the new procedure in hot topics, which were frequently reported in these years. In this book, the professionals of elastography show the mechanism, availability and how to use this technology in a clinical field of elastography. The comprehension of elastography could be a great help for better dealing and for understanding of liver biopsy.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 59
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    Publication Date: 2022-01-31
    Description: This book covers different aspects on the understanding of mechanisms, effects, and management of cholestasis. This unique compendium contains important citations, an invaluable amount of research work, and many applications, which are outstanding resources for clinicians, pharmacists, biochemists, upper-level undergraduate, graduate, and continuing-education students who are dedicated to discovering new knowledge on cholestasis.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 60
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    Publication Date: 2022-01-31
    Description: Currently, aortic stenosis (AS) is the most prevalent valvular disease in developed countries. Pathological and molecular mechanisms of AS have been investigated in many aspects. And new therapeutic devices such as transcatheter aortic valve implantation have been developed as a less invasive treatment for high-risk patients. Due to advanced prevalent age of AS, further discovery and technology are required to treat elderly patients for longer life expectancy. This book is an effort to present an up-to-date account of existing knowledge, involving recent development in this field. Various opinion leaders described details of established knowledge or newly recognized advances associated with diagnosis, treatment and mechanism. Thus, this book will enable close intercommunication to another field and collaboration technology for new devices. We hope that it will be an important source, not only for clinicians, but also for general practitioners, contributing to development of better therapeutic adjuncts in the future.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 61
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    Publication Date: 2022-01-31
    Description: Gestational diabetes mellitus is defined as hyperglycemia with onset or first recognition during pregnancy. The incidence of gestational diabetes is still increasing and this pathological condition has strong association with adverse pregnancy outcomes. Since gestational diabetes can have long-term pathological consequences for both mother and the child, it is important that it is promptly recognized and adequately managed. Treatment of gestational diabetes is aimed to maintain euglycemia and it should involve regular glucose monitoring, dietary modifications, life style changes, appropriate physical activity, and when necessary, pharmacotherapy. Adequate glycemic control throughout the pregnancy can notably reduce the occurrence of specific adverse perinatal and maternal outcomes. In a long-term prospect, in order to prevent development of diabetes later in life, as well to avoid associated complications, an adequate education on lifestyle modifications should start in pregnancy and continue postpartum.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    Publication Date: 2022-01-31
    Description: This book is dedicated to inflammatory bowel disease, and the authors discuss the advances in the pathogenesis of inflammatory bowel disease, as well as several new parameters involved in the etiopathogeny of Crohn's disease and ulcerative colitis, such as intestinal barrier dysfunction and the roles of TH 17 cells and IL 17 in the immune response in inflammatory bowel disease. The book also focuses on several relevant clinical points, such as pregnancy during inflammatory bowel disease and the health-related quality of life as an end point of the different treatments of the diseases. Finally, advances in management of patients with inflammatory bowel disease are discussed, especially in a complete review of the recent literature.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    Publication Date: 2022-01-31
    Description: Ulcerative Colitis (UC) is a rapidly evolving medical field, and will continue to be very exiting in the next few decades. Although the underlying cause of this disease is still unknown, results in research dealing with various issues related to this disease are published every day. Chapters included in this book review the most recent literature on related advancements in regard to this chronic disease, which is controllable but not curable. Aspects like epidemiology, pathophysiology, genetics, incriminated etiologies, clinical aspects, complications, and disease management, including advancements in the diagnostic and therapeutic options, were documented by well known clinicians, researchers, and world wide authorities in their fields. This book on UC will be a valuable addition to each doctor's library interested in this subject, or for physicians dealing with patients suffering from this disease. Authors have also included figures and diagrams to depict their point, and to easily reach the minds of the readers in the simplest way.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Endocarditis is a disease that occurs as a result of the inflammation of the endocardium. It is an inflammatory process located in the inner lining of the cardiac chambers and native or prosthetic valves. It is characterized by colonization or invasion of the heart valve vegetations composed of platelets forming, fibrin and microcolonies of microorganisms, and occasionally of inflammatory cells. Other structures may also be affected, such as the interventricular septum, chordae tendineae, the mural endocardium or even intra-cardiac implants. The book covers, with scientific rigour, the most prevalent causes and current treatments of endocarditis, as well as the cases when the organs remote from the heart are affected by this disease.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Liver biopsy, first performed by Paul Ehrlich in 1883, remains an important diagnostic procedure for the management of hepatobiliary disorders and the candidate/donated organ for transplantation. The book "Liver biopsy in Modern Medicine" comprises 21 chapters covering the various aspects of the biopsy procedure in detail and provides an up-to-date insightful coverage to the recent advances in the management of the various disorders with liver biospy. This book will keep up with cutting edge understanding of liver biopsy to many clinicians, physicians, scientists, pharmaceutics, engineers and other experts in a wide variety of different disciplines.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 66
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book is intended to act as an up-to-date reference point and knowledge developer for all readers interested in the area of gastroenterology and in particular, Ulcerative Colitis. All authors of the chapters are experts in their fields of publication, and deserve individual credit and praise for their contributions to the world of Ulcerative Colitis. We hope that you will find this publication informative, stimulating, and a reference point for the area of Ulcerative colitis as we move forward in our understanding of the field of medicine.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book aims to provide readers with a general as well as an advanced overview of the key trends in endocrine disorders. While covering a variety of topics ranging from thyroid carcinogenesis and pituitary adenomas to adrenal tumors and metabolic bone disease, this book also focuses on more specific issues not yet fully elucidated (e.g. the molecular pathways involved in thyrotropin beta gene regulation or monogenic phosphate balance disorders). Readers of different fields and background will have the opportunity to update their knowledge and more importantly to clarify areas of uncertainty and controversies in several topics of endocrine disorders.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book provides the most up-to-date information on the basic and clinical aspects of endocrinology. It offers both researchers and clinicians experts, gold-standard analysis of endocrine research and translation into the treatment of diseases such as insulinoma, endocrine disease in pregnancy and steroid induced osteoporosis. Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. Presents a uniquely comprehensive look at all aspects of endocrine changes in pregnancy and cardiovascular effects of androgens.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Alcoholic liver disease occurs after prolonged heavy drinking. Not everyone who drinks alcohol in excess develops serious forms of alcoholic liver disease. It is likely that genetic factors determine this individual susceptibility, and a family history of chronic liver disease may indicate a higher risk. Other factors include being overweight and iron overload. This book presents state-of-the-art information summarizing the current understanding of a range of alcoholic liver diseases. It is hoped that the target readers - hepatologists, clinicians, researchers and academicians - will be afforded new ideas and exposed to subjects well beyond their own scientific disciplines. Additionally, students and those who wish to increase their knowledge will find this book a valuable source of information.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 70
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book is a compilation of reviews about the complication of Type 1 Diabetes. T1D is a classic autoimmune disease. Genetic factors are clearly determinant but cannot explain the rapid, even overwhelming expanse of this disease. Understanding etiology and pathogenesis of this disease is essential. The complications associated with T1D cover a range of clinical obstacles. A number of experts in the field have covered a range of topics for consideration that are applicable to researcher and clinician alike. This book provides apt descriptions of cutting edge technologies and applications in the ever going search for treatments and cure for diabetes.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 71
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 72
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Type 2 diabetes is estimated to affect 120 million people worldwide- and according to projections from the World Health Organization this number is expected to double over the next two decades. Novel, cost-effective strategies are needed to reverse the global epidemic of obesity which is driving the increased occurrence of type 2 diabetes and to less the burden of diabetic vascular complications. In the current volume, Topics in the Prevention, Treatment and Complications of Type 2 Diabetes, experts in biology and medicine from four different continents contribute important information and cutting-edge scientific knowledge on a variety of topics relevant to the management and prevention of diabetes and related illnesses.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 73
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Endoscopy has had a big role in the development of modern gastroenterology. Modern endoscopy will certainly be more therapeutic. It started with endoscopic hemostasis and polipectomy, than beginning of the 1970's with the advent of endoscopic sphincterotomy extended to biliopancreatic pathology and has a huge impact in this difficult pathology. Plastic stents made the first steps in endoscopic palliation of neoplastic jaundice, metallic stents, covered or uncovered are better for biliary palliation and can be used also for palliation neoplastic obstruction at different levels of the digestive tube. Resection of digestive tumors has evolved now to sub-mucosal resection, looking to have one-piece complete resection. Interventional endoscopy is now very complex and takes a lot of time for endoscopists to learn properly these techniques. This book is a very good up-to-date overview of new techniques of interventional endoscopy for those who want to learn or develop their knowledges in this field.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: As result of progress, endoscopy has became more complex, using more sophisticated devices and has claimed a special form. In this moment, the gastroenterologist performing endoscopy has to be an expert in macroscopic view of the lesions in the gut, with good skills for using standard endoscopes, with good experience in ultrasound (for performing endoscopic ultrasound), with pathology experience for confocal examination. It is compulsory to get experience and to have patience and attention for the follow-up of thousands of images transmitted during capsule endoscopy or to have knowledge in physics necessary for autofluorescence imaging endoscopy. Therefore, the idea of an endoscopist has changed. Examinations mentioned need a special formation, a superior level of instruction, accessible to those who have already gained enough experience in basic diagnostic endoscopy. This is the reason for what these new issues of endoscopy are presented in this book of New techniques in Gastrointestinal Endoscopy.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 75
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Pituitary Adenomas is a comprehensive book about the most common pathology of the pituitary gland in the sellar region. The book chapters include epidemiology, symptoms and signs, clinical, imaging, immunohistochemical and ultrastructural pathological diagnosis, therapeutic approaches and outcome of the functional and non-functional pituitary tumors. Therapies include medications, endoscopic transphenoidal and open surgeries; radiotherapy includes gamma knife radiosurgery. Visual symptoms has important and characteristic patterns which has discussed in one specific chapter. Endocrine secretion is another characteristic in 40% of pituitary adenomas. Therefore, another chapter presents it. Stereotactic radiosurgery and endoscopic surgery both have special role in recent decades. Thus, they have considered specifically, too. Authors expect to give excellent insight in pituitary adenoma to the book readers.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Peptic ulcer disease is one of the most common chronic infections in human population. Despite centuries of study, it still troubles a lot of people, especially in the third world countries, and it can lead to other more serious complications such as cancers or even to death sometimes. This book is a snapshot of the current view of peptic ulcer disease. It includes 5 sections and 25 chapters contributed by researchers from 15 countries spread out in Africa, Asia, Europe, North America and South America. It covers the causes of the disease, epidemiology, pathophysiology, molecular-cellular mechanisms, clinical care, and alternative medicine. Each chapter provides a unique view. The book is not only for professionals, but also suitable for regular readers at all levels.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book explains the basic science of steroids and is targeted towards professionals engaged in health services. It should be noted that medical science evolves rapidly and some information like the understanding of steroids and their therapeutic use may change with new concepts quickly. Steroids are either naturally occurring or synthetic fat-soluble organic compounds. They are found in plants, animals, and fungi. They mediate a very diverse set of biological responses. The most widespread steroid in the body is cholesterol, an essential component of cell membranes, and the starting point for the synthesis of other steroids. Since the science of steroids has an enormous scope, we decided to put the clinical aspects of steroids in a different book titled "Steroids-Clinical Aspects". The two books complete each other. We hope that the reader will gain valuable information from both books and enrich their knowledge about this fascinating topic.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Glucose is an essential metabolic substrate of all mammalian cells being the major carbohydrate presented to the cell for energy production and also many other anabolic requirements. Hypoglycemia is a disorder where the glucose serum concentration is usually low. The organism usually keeps the glucose serum concentration in a range of 70 to 110 mL/dL of blood. In hypoglycemia the glucose concentration normally remains lower than 50 mL/dL of blood. This book provides an abundance of information for all who need them in order to help many people worldwide.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book is intended as an overview of recent progress in type 1 diabetes research worldwide, with a focus on different research areas relevant to this disease. These include: diabetes mellitus and complications, psychological aspects of diabetes, perspectives of diabetes pathogenesis, identification and monitoring of diabetes mellitus, and alternative treatments for diabetes. In preparing this book, leading investigators from several countries in these five different categories were invited to contribute a chapter to this book. We have striven for a coherent presentation of concepts based on experiments and observation from the authors own research and from existing published reports. Therefore, the materials presented in this book are expected to be up to date in each research area. While there is no doubt that this book may have omitted some important findings in diabetes field, we hope the information included in this book will be useful for both basic science and clinical investigators. We also hope that diabetes patients and their family will benefit from reading the chapters in this book.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: The first chapter of the book reports on the management of Langerhans cell histiocytosis (LCH)-induced central diabetes insipidus and its associated endocrinological/neurological sequelae in the national survey. The next chapter addresses DI and head injuries. Next, the management of neuroendocrine instability during maintenance of potential organ donors is described. Organ transplants have gradually increased worldwide. To have maintenance of appropriate potential organs, AVP is needed. Furthermore, nephrogenic DI-the potential therapeutic drugs and analysis of membrane protein stability is the topic of the next two chapters, followed by new insights into the diagnosis and management of pregnancy-related DI. The seventh chapter reports on the problems with differential diagnosis in a case of central DI in a female patient with bipolar disorder. The lithium treatment usually resulted in nephrogenic DI. Finally, over the last years, the development of MRI imaging on the pituitary gland with the stalk and hypothalamus has advanced. The final chapter interprets imaging techniques in DI in detail.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Over the last few decades the prevalence of diabetes has dramatically grown in most regions of the world. In 2010, 285 million people were diagnosed with diabetes and it is estimated that the number will increase to 438 million in 2030. Hypoglycemia is a disorder where the glucose serum concentration is usually low. The organism usually keeps the serum glucose concentration in a range of 70 to 110 mL/dL of blood. In hypoglycemia the glucose concentration normally remains lower than 50 mL/dL of blood. Hopefully, this book will be of help to many scientists, doctors, pharmacists, chemicals, and other experts in a variety of disciplines, both academic and industrial. In addition to supporting researcher and development, this book should be suitable for teaching.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 82
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book is a compilation of reviews about the pathogenesis of Type 1 Diabetes. T1D is a classic autoimmune disease. Genetic factors are clearly determinant but cannot explain the rapid, even overwhelming expanse of this disease. Understanding etiology and pathogenesis of this disease is essential. A number of experts in the field have covered a range of topics for consideration that are applicable to researcher and clinician alike. This book provides apt descriptions of cutting edge technologies and applications in the ever going search for treatments and cure for diabetes. Areas including T cell development, innate immune responses, imaging of pancreata, potential viral initiators, etc. are considered.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book is intended to act as an up to date reference point and knowledge developer for all readers interested in the area of gastroenterology and in particular Ulcerative Colitis. All of the chapter authors are experts in their fields of publication and deserve individual credit and praise for their contributions to the world of Ulcerative Colitis. We hope that you will find this publication informative, stimulating and a reference point for the area of Ulcerative colitis as we move forward in our understanding of the field of medicine.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 84
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Dyslipidemia has a complex pathophysiology consisting of various genetic, lifestyle, and environmental factors. It has many adverse health impacts, notably in the development of chronic non-communicable diseases. Significant ethnic differences exist due to the prevalence and types of lipid disorders. While elevated serum total- and LDL-cholesterol are the main concern in Western populations, in other countries hypertriglyceridemia and low HDL-cholesterol are more prevalent. The latter types of lipid disorders are considered as components of the metabolic syndrome. The escalating trend of obesity, as well as changes in lifestyle and environmental factors will make dyslipidemia a global medical and public health threat, not only for adults but for the pediatric age group as well. Several experimental and clinical studies are still being conducted regarding the underlying mechanisms and treatment of dyslipidemia. The current book is providing a general overview of dyslipidemia from diverse aspects of pathophysiology, ethnic differences, prevention, health hazards, and treatment.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 85
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Endoscopy has had a major impact in the development of modern gastroenterology. By using different data it provided a better understanding of pathogenic mechanisms, described new entities and changed diagnostic and therapeutic strategies. Meanwhile, taking advantage of many technical advances, endoscopy has had a developed spectacularly. Video-endoscopes, magnification, confocal and narrow-band imaging endoscopes, endoscopic ultrasounds and enteroscopes emerged. Moreover, endoscopy has surpassed its function as an examination tool and it became a rapid and efficient therapeutic tool of low invasiveness. InTech Open Access Publisher selected several known names from all continents and countries with different levels of development. Multiple specific points of view, with respect to different origins of the authors were presented together with various topics regarding diagnostic or therapeutic endoscopy. This book represents a valuable tool for formation and continuous medical education in endoscopy considering the performances or technical possibilities in different parts of the world.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 86
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: The gastrostomy placement is a method of providing nutrition to the patients who are unable to eat. In this book you can find chapters focused on the use of gastrostomy in children, patients with neurological impairment and patients with head and neck tumours. Home enteral nutrition is suitable for all of these groups of patients and is far easier with gastrostomy. The new indications (especially in very young children) required new techniques such as: laparoscopic gastrostomy, laparoscopy assisted endoscopic gastrostomy with/without fundoplication, ultrasonography assisted gastronomy. All information about these techniques can be found in this book. This book does not serve as a basic textbook, but as an interesting reading material and as an aid for physicians who are already familiar with the indication for gastrostomy and want to know more.
    Keywords: Hepatology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
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  • 87
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Hypothyroidism is the most common thyroid disorder and it is significantly more frequent than presented - millions of people suffer from this disease without knowing it. People with this condition will have symptoms associated with slow metabolism. Estimates of subclinical hypothyroidism range between 3 to 8 %, increasing with age, whereas it more likely affects women than men. About 10% of women may have some degree of thyroid hormone deficiency. Hypothyroidism may affect lipid metabolism, neurological diseases or other clinical conditions. The book includes studies on advancements in diagnosis, regulation and replacement therapy, thyroid ultrasonography and radioiodine therapy for hypothyroidism. "Hypothyroidism - Influences and Treatments" contains many important specifications, results of scientific studies and innovations for endocrine practice.
    Keywords: Endocrinology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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