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  • Books  (221)
  • thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology  (97)
  • Oncology  (89)
  • thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering  (88)
  • Cell & Developmental Biology
  • Chemical Engineering
  • Humans
  • Inorganic Chemistry
  • energy
  • IntechOpen  (221)
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  • Books  (221)
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  • 1
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: In the past decade, we have witnessed innovation in surgical treatment for renal cell carcinoma (RCC), including robotic platforms with integration of imaging approaches, and advances in targeted therapy, immunotherapy, and combination therapy to treat patients with advanced RCC. This book presents updated information on the epidemiology, genetics, diagnosis, screening, and advances in the treatment and management of RCC. It is a useful resource for any clinician involved in the management of patients with RCC, as well as other physicians, researchers, and patients.
    Keywords: immunotherapy ; genetics ; ultrasound ; mri ; targeted therapy ; epigenetic ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 2
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: A dynamic system’s performance and stability can be significantly impacted by regular disturbance. Techniques for disturbance rejection control aim to reduce the effects of disturbances while maintaining desired system behavior. This book explores the definition, objectives, mechanisms of control, and applications of disturbance rejection control. It also examines the theoretical underpinnings and practical implementations of various disturbance rejection control systems with a focus on the significance of flexibility and resilience. Disturbances will occur in any dynamic system and they can be brought on by both internal and external uncertainties. The performance of the system is significantly impacted by these interruptions, which can also cause it to depart from intended set points or trajectories. To mitigate the impact of disturbances and maintain desired system behavior, disturbance rejection control mechanisms are employed. This book provides a summary of disturbance rejection control and its importance in numerous applications.
    Keywords: artificial intelligence ; genetic algorithm ; robust control ; pid controller ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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  • 3
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Pancreatic Cancer - Updates in Pathogenesis, Diagnosis and Therapies presents the most recent knowledge on pancreatic cancer, which is a deadly, challenging and catastrophic tumor with a high mortality rate. It is the seventh leading cause of cancer-related mortality worldwide. Pancreatic cancer can be diagnosed clinically, by laboratory measures, by imaging, and by pathological detection. Understanding tumor pathogenesis as well as tumor risk factors is necessary for successful treatment, as is early detection and multidisciplinary treatment. This book provides a comprehensive overview of pancreatic cancer in four sections. Chapters address such topics as prevention, screening, and detection; pathogenesis and risk factors; and pathology and management.
    Keywords: pancreas ; obesity ; epidemiology ; risk factors ; screening ; pathology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 4
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-07
    Description: This book offers a comprehensive overview of recent developments in the field of obesity. The chapters are authored by prominent scholars in the field with direct knowledge, through practice and research, of the real-world problems associated with obesity. Chapters address such topics as obesity in children, stigmatization of people with obesity, metabolic effects of obesity, recent advances in pharmacology and surgical interventions for obesity, and more.
    Keywords: inflammation ; oxidative stress ; energy ; metabolism ; neurodegeneration ; leptin ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 5
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book offers outstanding approaches to understanding the role of the tumor microenvironment (TME) in cancer development and metastasis. The TME, with its multifaced role, is fundamental in the control and exacerbation of almost all cancer types. The outcome of many solid tumors is dependent on the modulation of the TME. Local tumor immunity, which is crucial in the control of cancer promotion, is one of the leading compounds of the TME. This book presents new insights and provides detailed and updated descriptions of the role of the TME in the control and the development of almost all cancer types. This book is an authentic source of knowledge, useful for researchers, medical doctors, students, and all individuals interested in understanding the mechanisms of cancer control and development.
    Keywords: cancer ; metabolism ; lung cancer ; nutrients ; minimally invasive surgery ; liquid biopsy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 6
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book describes and discusses numerous new concepts and procedures for the diagnosis and management of all types of neurofibromatosis (NF). It includes five chapters that address numerous topics in the field, including the management of toxicities associated with NF treatment modalities. It provides useful information and data for both researchers and practitioners to develop new approaches for the management of NF.
    Keywords: Neurofibromatosis 1 ; Schwannomatosis ; Risk Factors ; Neurofibromatosis 2 ; Epidemiology ; Diagnosis ; Cancer Therapies ; Physiological Dysfunction ; Chemotherapy ; Surgery ; Monitoring ; Gene Immunotherapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 7
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: The book presents some recent specialized theoretical and practical works in the field of process control based on the model predictive control (MPC) method. It includes seven chapters that present studies on the application of MPC in various technical processes, such as the atmospheric plasma spray process, permanent magnet synchronous motors, monitoring of the pose of a walking person, monitoring of the heat treatment process of raw materials, discrete event processes, control of passenger vehicles, and natural gas sweetening processes. Chapters include examples and case studies from researchers in the field. This volume provides readers with new solutions and answers to questions related to the emerging applications of MPC and their implementation.
    Keywords: Plant Models Optimization ; Minimization Algorithms ; Control Strategies ; Stability ; Robustness ; Real-Time Applications ; Neural Network Model ; Predictive Control ; Adaptive Model ; Industry ; Smart Manufacturing ; Economy ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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  • 8
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Green computing involves developing, designing, engineering, producing, using, and disposing of computing modules and devices to reduce environmental hazards and pollution. Green computing technologies are crucial for protecting the planet from environmental hazards and pollution. This book presents new subjects and innovations in green computing technologies and in green computing and electronics industries. Chapters address such topics as green wearable sensors, variable renewable energy, managing energy consumption using the Internet of Things (IoT) and big data, using forest waste to produce biofuel and biodiesel, green computing in ophthalmological practice, and much more.
    Keywords: agriculture ; renewable energy ; biodiversity ; energy ; big data ; iot ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQD Environmental monitoring
    Language: English
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  • 9
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Solar energy is a significant renewable energy source that is abundant and environmentally friendly. Solar PV Panels – Recent Advances and Future Prospects provides a comprehensive overview of solar photovoltaic (PV) panels for direct electric power production. Chapters address such topics as fundamentals of solar PV panels; modeling, simulations, optimization, and economics of solar panels; solar panels testing; semiconductor materials for solar cells and panels; solar PV applications and policies; and solar PV and battery storage sizing for stand-alone and grid-connected applications.
    Keywords: solar cells ; renewable energy ; energy ; cfd ; 2d materials ; solar energy ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THV Alternative and renewable energy sources and technology
    Language: English
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  • 10
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book provides a comprehensive overview of multiple myeloma. It is organized into three sections with chapters addressing topics such as diagnosis, risk stratification, and management of multiple myeloma; treatment of multiple myeloma at diagnosis and at relapse; management of disease complications; and stem cell therapies, including autologous and allogeneic hematopoietic stem cell transplantation with a focus on autologous grafting using non-cryopreserved stem cells and performance of stem cell transplantation in outpatient settings.
    Keywords: cryopreservation ; chemotherapy ; quality of life ; hematopoietic stem cell transplantation ; monoclonal antibodies ; adverse effects ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 11
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: The idea of using robots in our daily lives was an inspiring research in the field of robotics during the last decades. Service robots can be found nowadays in warehouses, hospitals, retail stores, city streets, and industrial parks or as personal assistants. The effort on the development of these robots is confirmed by the amount of money invested in projects and companies, the creation on new start-ups worldwide, and, not less important, the quantity and quality of the manuscripts published in journals and conferences worldwide. This book is an outcome of research done by several researchers who have highly contributed to the field of service robots. The main goal of this book is to present the recent advances in the field of service robots.
    Keywords: robotics, agriculture, numerical simulation, uav, greenhouse, wireless networks ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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  • 12
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: This book presents recent research advances in autonomous mobile mapping robots, covering a range of topics. These include unconventional trajectories for mobile 3D scanning, key software components such as lidar odometry, look closure, pose graph SLAM, map refinement, path planning, and coverage algorithms. The book also explores multi-robot mapping and scalable algorithms for simultaneous localization and mapping. Finally, it delves into real-world applications like aerial 3D mapping and automotive SLAM in urban environments.
    Keywords: artificial intelligence ; path planning ; gnss ; uav ; mobile robots ; lidar ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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  • 13
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: With numerous new opportunities and challenges emerging from the topic of the cognition and control of complex systems, the methods related to PID control, or control based on a PID framework, will continue to grow and expand. This book covers some of the recent results that include improvements to the PID controller. Some examples of these improvements are as follows: •The novelty method of the variable, fractional-order PID controller •The optimization of PID controller, such as the hybrid LQR-PID controller by using genetic algorithm (GA) with the application for the control of helicopter systems •The optimized tuning approach of PID controller with disturbance rejection •A controller adjustment method based on the internal product of PID terms •The PI-PD controller, incorporated with the model-based feedforward control (FF) and the disturbance compensator (Kz), which is used for the control of magnetic levitation systems •The proper control with PID framework used to improve the cognition or identification for complex systems
    Keywords: parameter estimation, pid controller, robustness, disturbance rejection, industrial processes ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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  • 14
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: A proportional-integral-derivative (PID) controller is an instrument used in industrial control applications to regulate process variables such as temperature, pressure, flow, etc. PID controllers are still very much preferred in the industry due to their simplicity and ability to yield reasonable closed-loop performance. About 90% of industrial controllers are of the PID type. To meet the continuously evolving challenges in industrial process control, it is essential to formulate PID-based control strategies which can yield improved performance. The contents of this book will serve as a good introduction to PID controllers and equip readers to design such controllers for various industrial applications.
    Keywords: pid controller ; lung cancer ; microrna ; mimo ; numerical solution ; process control ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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  • 15
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: There are many different types of cancer. Some are very common; others are rare. Having some similar features, each cancer has its own characteristics and symptoms, which vary according to the type of cancer and where it is in the body. The treatment selected may be influenced by the patient's age, concurrent health problems, life expectancy, characteristics of the individual's cancer, the patient's goals of treatment, and the bias of the treating physician. In preparing this book, we have considered and reflected on the concept of the recent advances in cancer management and therapy as well as molecular applications in cancer therapy. The readers can find detailed information about the treatment and management of specific cancers in these book chapters.
    Keywords: breast cancer, immunotherapy, apoptosis, colorectal cancer, lung cancer, targeted therapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 16
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book covers specific chapters with fundamental and current concepts about the main primary intracranial tumors, aimed at general neurosurgeons, neurologists, oncologists, radiotherapists, and residents. They are everyday situations from the subspecialist routine that can become challenging for professionals outside referenced centers or working alone.
    Keywords: glioblastoma, magnetic resonance imaging, gliomas, immunotherapy, biomarker, chemotherapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 17
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: The current volume entitled, "Free Radicals and Diseases" integrates knowledge in free radical-associated diseases from the basic level to the advanced level, and from the bench side to bed side. The chapters in this book provide an extensive overview of the topic, including free radical formations and clinical interventions.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 18
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: This book covers a wide range of topics relating to advanced industrial robotics, sensors and automation technologies. Although being highly technical and complex in nature, the papers presented in this book represent some of the latest cutting edge technologies and advancements in industrial robotics technology. This book covers topics such as networking, properties of manipulators, forward and inverse robot arm kinematics, motion path-planning, machine vision and many other practical topics too numerous to list here. The authors and editor of this book wish to inspire people, especially young ones, to get involved with robotic and mechatronic engineering technology and to develop new and exciting practical applications, perhaps using the ideas and concepts presented herein.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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  • 19
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    IntechOpen | IntechOpen
    Publication Date: 2023-12-01
    Description: It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.
    Keywords: Oncology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 20
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Pancreatic cancer is one of the most lethal solid organ tumors with a poor five-year survival rate despite current oncological advances. The early and proper diagnosis of pancreatic cancer is of great importance for the improvement of the overall prognosis. This book provides an overview of the current challenges and states of pancreatic cancer and pancreatic neuroendocrine tumors, including information on diagnostic tools, treatment strategies, and mechanisms of pancreatic cancer therapy resistance.
    Keywords: immunotherapy, tumor microenvironment, irreversible electroporation, therapy, computer-assisted surgery ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 21
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Malnutrition is the specific condition produced by the intake of too few macronutrients, too many macronutrients (obesity), or inordinate amounts of inappropriate substances such as alcohol. Globally, malnutrition is a major nutritional disorder, especially in developing economies. Poor dietary habits and imbalanced nutrient intake result in adverse consequences on normal body functionality. This book highlights the major causes of malnutrition and how to overcome this problem. Chapters address such topics as energy metabolism and balance, diagnosis of malnutrition, negative effects of malnutrition, sugar and its impact on health, malnutrition in the elderly and children, and much more.
    Keywords: public health ; undernutrition ; cancer ; inflammation ; energy ; metabolism ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine::MBNH Personal & public health::MBNH3 Dietetics & nutrition
    Language: English
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  • 22
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book entitled Cervical Cancer - Screening, Treatment and Prevention Universal Protocols for Ultimate Control is the fourth successful endeavor of the Editor with InTech publisher. The four books serve as four pillars in cervical cancer control, globally. This book is unique and sensational. Public health "topics" are assuming a status of "phenomenon," through deliberations and research. Screening is riddled with global limitations of availability, affordability, acceptability, and accessibility. The treatment of precancers has questionable efficiency. Prevention is costly with the inclusion of HPV vaccine. This book helps to find the solutions. The authors, editor, and InTech publisher wish the readers a pleasant and purposeful reading. This book is a "readers' feast," "receivers' choice," and "respondents' delight." Enjoy and treasure the international facts and flavors.
    Keywords: human papillomavirus, biomarker, microbiome, carcinogenesis, radiation, genetic variation ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 23
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viruses. These carcinogens can induce specific genetic and epigenetic alterations in these tissues, leading to aberrant functioning of oncogenes and tumor suppressor genes. On the microRNAs (miRNAs) there are significant modifiers of both transcription and translation of oncogenes in carcinogenesis. In the last 50 years, several oncogenes and microRNAs related to these oncogenes have been identified in different types of human cancers. It is now clear that high expression of oncogenes, DNA damage response, and regulation of the cell cycle are related to the circadian clock. This book will mainly focus on the expressions of different oncogenes in breast, colon, and lung cancers. Moreover, readers will gain qualified scientific knowledge of the alterations in miRNAs in different types of cancers and the effects of the circadian clock on the expression of oncogenes in carcinogenesis.
    Keywords: breast cancer, colorectal cancer, lung cancer, mirna, dna repair, arsenic ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 24
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Pheochromocytoma, paraganglioma and neuroblastoma are the most common neural crest-derived tumors in adults and children, respectively. These neoplasms are associated with significant morbidity and mortality. Some international studies currently underway are researching and evaluating the presence of any similarities and differences between these tumors. Hopefully, future results will reveal several potential novel genes and pathways that might have major roles in the pathogenesis and progression of these neoplasms. This book discusses epidemiology, genetics, and treatment of these malignancies.
    Keywords: chemotherapy, metastasis, mirna, dna methylation, epigenetic, laparoscopic surgery ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 25
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book discusses the application of bioinformatics in cancer disease management. It covers general aspects of cancer as a disease but also as a success story in the translation of omics data in clinical settings. It provides an overview of the specific applications of bioinformatics tools in cancer epidemiology, prevention, and screening and in the identification of novel genetic and molecular biomarkers involved in cancer development. This is accomplished through the inclusion of numerous examples of the use of bioinformatics in precision oncology.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 26
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: New technological developments expand the technical connotation of industrial automation with control objects and control objectives also greatly expanded, thus promoting development direction of industrial automation technology to intellectualization. This book is a collection of articles on novel approaches to current problems in industrial automation and encompasses multidisciplinary areas such as distributed system architecture, application of non-destructive distributed sensor system, joint simulation technology, and a summary of intelligent transition. New Trends in Industrial Automation provides useful reference material for technical workers in the field of industrial automation, including undergraduate and postgraduate students, academicians, researchers, and practicing engineers.
    Keywords: vibration, distributed computing, inverse problem, dynamic characteristics, oee ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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  • 27
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Glioblastoma (GBM) is a common and aggressive brain cancer with features of necrosis and endothelial proliferation in the histopathologic examination. Its presentation and management depend on tumor location, size, grade, and underlying histopathological characteristics. GBM tumors have clinical features of increased intracranial pressure, focal neurological deficits, or seizures (generalized or partial) with rapid progression. This book discusses GBM and its diagnosis, treatment, and management.
    Keywords: immunotherapy ; chemotherapy ; glioma ; genetics ; biomarker ; elderly ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 28
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Hepatocellular carcinoma (HCC) currently ranks as the third most common cause of death. As the primary malignancy of the liver is directly related to an underlying liver condition, its incidence and profile are expected to change soon. While effective prevention programs and antiviral therapies for hepatitis B and C will lower the incidence of HCC, emerging socioeconomic issues will deliver new at-risk populations. Moreover, diagnostic techniques and protocols have undergone significant advancements. Reliance on contrast enhanced ultrasound has been re-evaluated, imaging methods being considered as sufficient diagnostic tools. Molecular characterization remains desirable, since chemotherapeutic agents still have limited applicability. In light of recent diagnostic advancements and novel therapeutic solutions, it is our belief that a comprehensive update on recent paradigm shifts and interesting upcoming developments is highly needed.
    Keywords: cancer, targeted therapy, obesity, immunotherapy, metabolism, microrna ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 29
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Metastasis is the major cause of cancer-related death. It is a multistep process. The mechanism underlying metastasis is complicated and poorly understood. Recent advances in tumor metastasis research have led to improved diagnosis and clinical management of cancer. However, new strategies on metastasis treatment are urgently needed, especially the novel biomarkers discovery and targeted therapy. This book is designed to present the most recent advances in tumor metastasis.
    Keywords: cancer, breast cancer, drug delivery, exosomes, extracellular matrix, ovarian cancer ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 30
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Melanoma is an aggressive type of cancer for which treatment has dramatically evolved during the last 15 years, improving response and survival figures. This book, written by a diverse panel of experts, presents a description of the most relevant aspects of the epidemiology, diagnosis, local treatment, prognostic biomarkers and treatment for advanced disease, including the most recent research on novel molecules that are either approved or are undergoing clinical development. It includes insights on such challenging topics as when immunotherapy should be started in BRAF mutant patients, or which is the most appropriate treatment algorithm in those cases, as well as how to handle difficult and poor-prognosis melanoma cases, such as patients with brain metastases or patients with the uveal disease.
    Keywords: immunotherapy ; targeted therapy ; histopathology ; cancer ; radiotherapy ; immune checkpoint inhibitors ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 31
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas.
    Keywords: biomarkers, immunotherapy, chemotherapy, melanoma, targeted therapy, squamous cell carcinoma ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 32
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a number of putative therapeutic targets, including signal transduction pathways, metabolic and epigenetic alterations in tumor cells, the tumor microenvironment, the gut microbiome, and functions of immune effector cells. Given the multi-step nature of most cancers, including HCC, future drug development will most likely require combination therapies that will simultaneously target multiple steps in hepatocarcinogenesis.
    Keywords: hepatocellular carcinoma ; liver cirrhosis ; inflammation ; biomarkers ; immunotherapy ; gene expression ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-04-11
    Description: This Edited Volume “Nanogenerators and Self-Powered Systems” is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of nanotechnology and nanomaterials. The book comprises single chapters authored by various researchers and edited by an expert active in harnessing the ubiquitously available biomechanical energies to power portable electronics research area. All chapters are complete in themselves but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on nanotechnology and nanomaterials and opening new possible research paths for further novel developments.
    Keywords: energy ; sensors ; mems ; solar energy ; solar cells ; photovoltaic ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THV Alternative and renewable energy sources and technology
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    Publication Date: 2024-04-11
    Description: The Industrial Revolution introduced machines to humankind. In the 20th century, robots, which were produced only as toys before, began to be used for business applications. This robotic technology, which has spread to the world in a short time, is now being used in a variety of areas, from cargo transportation to car painting, from electronic card production to material selection, and from surgery to rehabilitation. This book explores the fantastic world of robotics, including current technology and applications as well as the latest advancements.
    Keywords: Electronics & communications engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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  • 35
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    Publication Date: 2024-03-31
    Description: Recent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin’s drug resistance and critical side effects.
    Keywords: immunotherapy, doxorubicin, cancer immunotherapy, cancer, optimization, nanoparticles ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 36
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    Publication Date: 2024-04-11
    Description: The automobile industry is tremendously peculiar due to several strict requirements regarding functional reliability, safety standards, comfort level, high-volume production, and environmental limits. In addition, the industry is experiencing a disruptive evolution of modern vehicle research and design: electrification, connectivity, and autonomous driving. This book provides a robust overview of automotive engineering, including new proposals and the latest trends in road vehicle systems and sub-systems. Each chapter presents a rigorous analysis or a new solution in a clear and concise manner, such that professional and academic readers will appreciate both the theory dissertation and the industrial application.
    Keywords: hydrogen storage, graphene, simulation, nanocomposites, energy, kinetics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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  • 37
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    Publication Date: 2024-03-31
    Description: This book deals with the rapid progress in the area of myelodysplastic syndromes (MDS). MDS are a group of age-associated heterogeneous malignant bone marrow stem cell disorders. MDS are characterized by ineffective hematopoiesis, which leads to refractory cytopenias and to clonal instability. Patients with MDS have myeloid dysplasia, intramedullary apoptosis and an increased risk of transformation to acute myeloid leukemia (AML). The use of next generation sequencing has allowed for the identification of molecular mutations in several genes in about 90% of MDS patients. Several mutations will likely be incorporated into future prognostic scoring systems for MDS. About 50% of MDS cases are characterized by the presence of cytogenetic abnormalities. The correct morphological and cytogenetic analysis interpretation plays an important role in diagnosis and prognosis of these disorders. Cell death and an inflammatory gene signature are associated with MDS. Better understanding of the genetic and molecular mechanisms of MDS pathogenesis provides an opportunity for new treatment strategies to be developed. Promising novel therapies targeting pathophysiological mechanisms of MDS are being studied but the drugs currently used in MDS therapy remain limited. The only curative therapy for MDS is allogeneic hematopoietic stem cell transplantation. Recent advances in strategies to minimize transplant-related toxicity make this treatment possible for more MDS patients who are sufficiently fit.
    Keywords: cytokines, pathogenesis, micrornas, dendritic cells, behçet’s disease, vasculitis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 38
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    Publication Date: 2024-03-31
    Description: This book is a comprehensive overview of the recent developments in the clinical and research fields of multiple myeloma. It is divided into three main sections that cover a wide range of topics, including: epidemiology and pathogenesis of the disease, genetic targets and pathways, resistance to novel therapies, angiogenesis and anti-angiogenesis, hematopoietic stem cell transplantation, role of radiology and radiotherapy in myeloma, infectious complications, and management of multiple myeloma in resource-poor countries.
    Keywords: hematopoietic stem cell transplantation, monoclonal antibodies, novel therapies, epidemiology, risk factors, angiogenesis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-03-31
    Description: This book aims to foster collaboration between world-class bench scientists and clinicians in the fields of oncology, surgery, and pathology as they come together to highlight the complexity and diversity of soft tissue tumors as well as recent advances in their diagnosis and clinical management.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 40
    Publication Date: 2024-03-31
    Description: The aim of this book is to provide an overview of the importance of exosomes in the biomedical field, which involves in novel implications of exosomes in diagnosis and treatment of cancer and infectious diseases. The book would definitely be an ideal source of scientific information of exosomes to researchers and scientists involved in biomedicine, biology, and other areas involving cancer and infectious diseases.
    Keywords: biomarkers, extracellular vesicles, pathogenesis, multiple myeloma, liquid biopsy, endothelial cells ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 41
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    Publication Date: 2024-04-11
    Description: Carbon Nanotubes - Recent Advances, New Perspectives and Potential Applications covers all the important nanotechnological aspects of carbon materials, including their growth and characterization, processing and fabrication, development and potential applications. Recent developments, innovative preparation methods and promising new frontiers around this advanced nanotechnology are reviewed under the editorship of an internationally renowned scientist. This book will be useful to a diverse range of readers and will be important for research organizations, government research centers, academic libraries, and those involved in the research and development of carbon materials.
    Keywords: nanoparticles ; nanocomposites ; energy ; wastewater treatment ; nanofibers ; conductivity ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 42
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    Publication Date: 2024-03-31
    Description: Lung cancer continues to be the leading cause of cancer mortality worldwide among both men and women. Recent advances in prevention, screening and management in the past decade have led to significant improvements in survival and quality of life. Local treatments like minimally invasive surgery, radiotherapy, and image-guided ablation have contributed to improving the effectiveness and tolerability of potentially curative treatments in early-stage, locally advanced, and oligometastatic/oligoprogressive disease. Chemotherapy, targeted therapy, immunotherapy, and palliative local therapy options have expanded rapidly, with new regimens showing improved outcomes even for those with widely metastatic disease. This book comprehensively reviews the evidence that has driven personalized medicine, based on a variety of multidisciplinary perspectives by international lung cancer experts.
    Keywords: minimally invasive surgery, robotic surgery, immunotherapy, radiotherapy, mirna, liquid biopsy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-03-31
    Description: Cancer mortality and morbidity are primarily brought on by metastasis. The ability of neoplastic cells to spread and colonize distant tissues is their most dangerous trait. Most malignancies are curable when they are detected early and have not spread outside of the original tissue. However, cancer is frequently incurable when tumor cells have created colonies elsewhere. Thus, the book content This book provides comprehensive information on cancer metastasis, along with references to specific cancer cases. The topics discussed include invasion by perturbation of cell-cell and cell-matrix adhesion, matrix degradation, motility, intravasation, extravasation, metastatic colonization, metastasis and angiogenesis. Molecular mechanisms, the metastatic process, and palliative bone metastasis therapy are also considered.
    Keywords: breast cancer ; immunotherapy ; epigenetics ; lung cancer ; extracellular vesicles ; targeted therapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-04-11
    Description: Collaborative and Humanoid Robots guides readers through the fundamentals and state-of-the-art concepts and future expectations of robotics. It showcases interesting research topics on robots and cobots by researchers, industry practitioners, and academics. Divided into two sections on “Collaborative Robots” and “Humanoid Robots,” this book includes surveys of recent publications that investigative the interaction between humanoid robots and humans; safe adaptive trajectory tracking control of robots; 3D printed, self-learning robots; robot trajectory, guidance, and control; social robots; Tiny Blind assistive humanoid robots; and more.
    Keywords: safety, artificial intelligence, alzheimer’s disease, dementia, industry 4.0, security ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-03-31
    Description: Among the deadliest type of cancers, lung cancer faces several challenges in diagnosis and treatment: late diagnosis and misdiagnosis, inadequate tumor sampling, and resistance development to current therapies, among others. Together with advances in the understanding of molecular features, factors, and mechanisms involved in initiation and tumor progression, important improvements have occurred in diagnostics and therapeutics in the shape of advances in molecular genotyping, procedures for sampling, new potential, and less invasive sources of samples for the diagnosis and development of new targeted therapies. The aim of this book is to provide an exciting read on strategies in the diagnosis and therapy of lung cancer.
    Keywords: immunotherapy, biomarker, metabolomics, epigenetic, cancer stem cells, methylation ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-04-05
    Description: Corals have thrived on the bottom of the ocean for millions of years. These fascinating animals are currently forced to cope with the rapid changes caused by humans to avoid extinction. How are corals changing their way of processing energy from different sources? What do we know about the corals living in the unseen depths of certain seamounts? What is the impact of oil spills and what can we do? How are coral reefs all over the world to be restored? What is the socioeconomic importance of these habitats, and what do we gain or lose with their survival or their demise? By involving scientists and conservationists from different areas of the world, this book answers these and other questions about corals, the habitat they form, and the influence that we have on them.
    Keywords: climate change ; conservation ; energy ; bioremediation ; metabolism ; probiotics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSP Hydrobiology::PSPM Marine biology
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    Publication Date: 2024-04-11
    Description: The purpose of this book is to present some uses of the Kalman filter (KF) in engineering activities that can produce a robust and technically acceptable result while keeping as close as possible to the optimal (most accurate) solution. KF sub-optimization is often required, due to the realities of implementation and real-life operational conditions. The book brings together the experiences of specialists from different engineering areas using the KF in their practice.
    Keywords: Electronics & communications engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: Mass production companies have become obliged to reduce their production costs and sell more products with lower profit margins in order to survive in competitive market conditions. The complexity and automation level of machinery are continuously growing. This development calls for some of the most critical issues that are reliability and dependability of automatic systems. In the future, machines will be monitored remotely, and computer-aided techniques will be employed to detect faults in the future, and also there will be unmanned factories where machines and systems communicate to each other, detect their own faults, and can remotely intercept their faults. The pioneer studies of such systems are fault diagnosis studies. Thus, we hope that this book will contribute to the literature in this regard.
    Keywords: condition monitoring, fault detection, fault isolation, kalman filter, signal processing, principal component analysis ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: The book "RoCKIn - Benchmarking Through Robot Competitions" describes the activities and achievements on the promotion of Robotics research and benchmarking in Europe through robot competitions, carried out within the framework of the RoCKIn ("Robot Competitions Kick Innovation in Cognitive Systems and Robotics") Coordination Action, a project funded by the European Commission (EC) 7th Framework Programme (FP7). RoCKIn was one of the two pioneer projects on robot competitions in Europe funded by the EC, representing the acknowledgment of robot competitions as important tools to advance research on Robotics, besides education and public awareness of Robotics. Two challenges were selected for the RoCKIn competitions due to their high relevance and impact on Europe's societal and industrial needs: domestic service robots (RoCKIn@Home) and innovative robot applications in industry (RoCKIn@Work). Along the book chapters the reader will find details on RoCKIn@Home and RoCKIn@Work, and about the activities carried out during the project lifetime, namely the developed open domain test beds for competitions targeting the two challenges and usable by researchers worldwide; the scoring and benchmarking methods to assess the performance of robot systems and subsystems; and the building up of a community of new teams. The book ends with an assessment by the project industrial partner about the impact of RoCKIn and other robot competitions on the industrial robot markets. The project work was funded by the European Commission (EC) 7th Framework Programme (FP7), under the 9th Call for projects on Information and Communication Technologies. The publishing of this book was funded by the EC FP7 Post-Grant Open Access Pilot programme.
    Keywords: robotics, domestic robots, industrial robots, person and object detection and recognition, ground truth ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-03-31
    Description: Human life relies on two basic supplies from nature: oxygen and food. Oxygen can be utilized directly, but food has to go through a process of digestion to become usable nutrients. The esophagus represents the beginning of this long journey. Because of its critical location, esophageal cancer is one of the deadliest malignancies in the world, and furthermore its incidence has been rising steadily year after year while other cancers are declining. It is predicted that by the year 2035 the esophageal cancer population will increase by 77.4% and become one of top global concerns. This book covers many aspects of esophageal cancer, through which we hope to raise the awareness of professionals as well as non-professionals about this disease.
    Keywords: immunotherapy, regenerative medicine, tumor microenvironment, gerd, laryngectomy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-04-11
    Description: This book focuses on the applications of robust and adaptive control approaches to practical systems. The proposed control systems hold two important features: (1) The system is robust with the variation in plant parameters and disturbances (2) The system adapts to parametric uncertainties even in the unknown plant structure by self-training and self-estimating the unknown factors. The various kinds of robust adaptive controls represented in this book are composed of sliding mode control, model-reference adaptive control, gain-scheduling, H-infinity, model-predictive control, fuzzy logic, neural networks, machine learning, and so on. The control objects are very abundant, from cranes, aircrafts, and wind turbines to automobile, medical and sport machines, combustion engines, and electrical machines.
    Keywords: adaptive control, sliding mode control, machine learning, energy, neural networks, uav ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-03-31
    Description: In this book the reader will find a collection of chapters written by different research teams describing different aspects of peripheral T-cell lymphoma pathobiology, classification, and treatment. This work is mainly addressed to researchers already working in this area, but it is also accessible to anyone with a scientific background who desires to have an updated overview of the recent progress in this domain. It will also be valuable to scientists and physicians who have become newly involved in this field. Each chapter is self-contained and can be read independently of the others. This book intends to provide highlights of the current research as well as the current gold standards for diagnosis and treatment of these diseases, showing the recent advances in the personalized approach to T-cell derived lymphomas.
    Keywords: epigenetics, genomics, targeted therapy, precision medicine, transcriptomics, tyrosine kinase inhibitors ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-03-31
    Description: Colorectal cancer is the third most common cancer diagnosed in both men and women worldwide. This book examines state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. It emphasizes the importance of a multidisciplinary approach involving multiple specialties, including surgery, gastroenterology, radiology, biology, oncology, radiotherapy, nuclear medicine, and physiotherapy.
    Keywords: colon cancer, immunotherapy, mri, targeted therapy, mortality, imaging ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-04-11
    Description: PID Control for Industrial Processes presents a clear, multidimensional representation of proportional - integral - derivative (PID) control for both students and specialists working in the area of PID control. It mainly focuses on the theory and application of PID control in industrial processes. It incorporates recent developments in PID control technology in industrial practice. Emphasis has been given to finding the best possible approach to develop a simple and optimal solution for industrial users. This book includes several chapters that cover a broad range of topics and priority has been given to subjects that cover real-world examples and case studies. The book is focused on approaches for controller tuning, i.e., method bases on open-loop plant tests and closed-loop experiments.
    Keywords: pid controller, evolutionary algorithms, distillation column, process control, pso ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: Progress in industrialization and automation engineering is creating many new opportunities in the autonomous systems industry. With the uncertain and highly nonlinear dynamics of the real world where these new technologies will be deployed, a reliable control strategy is necessary. This book provides a high-level discussion on model-based control engineering and its various applications.
    Keywords: Electronics & communications engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: Over the past few decades, extensive research has been conducted on the applications of agricultural robots and automation to a variety of field and greenhouse operations, and technical fundamentals and their feasibility have also been widely demonstrated. Due to the unstructured environment, adverse interference and complicated and diversified operation process are the key of blocking its commercialization in robotic agricultural operations. Because of the development of automation techniques, smart sensors, and information techniques, some types of agricultural robots have achieved considerable success in recent years. This book intends to provide the reader with a comprehensive overview of the current state of the art in agricultural robots, fundamentals, and applications in robotic agricultural operations.
    Keywords: precision agriculture, image processing, neural network, ros, greenhouse, weed control ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-03-31
    Description: An understanding of the molecular pathogenesis of colorectal cancer by researchers and clinicians is essential to facilitate progress in improving patient outcomes in this common cancer that still carries a poor prognosis if not identified early. This book covers the major areas of importance in the field, incorporating new knowledge that has arisen due to the advancement of molecular techniques and the ability to correlate molecular changes with clinical behaviour of tumours. Each chapter is a summary written by experts, concisely summarising current data as well as highlighting potential areas for advancement. Appreciating the differences between tumours on a molecular level is the key to developing and delivering precision medicine, and nowhere is this more critically required than in the field of colorectal cancer.
    Keywords: epigenetics, biomarker, mass spectrometry, proteomics, dna methylation, personalized medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-03-31
    Description: Neoplasm refers to an abnormal tissue growth that arises as a consequence of rapid cell proliferation and continues to grow abnormally even after terminating the stimuli that had instigated the change. It lacks partial or complete functional coordination with that of the normal tissues. Neoplasms are classified depending on the degree and type of tissues involved. Carcinogenesis is a multistep process where a plethora of endogenous and exogenous factors turns out genetic and epigenetic modifications, which collectively amend some critical cellular pathways controlling the proliferation, apoptosis, and differentiation. The cells having aberrant modifications are transformed into malignant ones of which the clonal expansion results in the development of cancer. This book provides the reader with a comprehensive overview of various cancer types along with their molecular mechanisms of initiation and progression. It also describes the current knowledge about the state-of-the-art measures being employed in cancer diagnosis and therapeutics. Particular attention is paid to make this book equally useful for students, practitioners, and expert scientists.
    Keywords: cancer, biomarkers, immunotherapy, surgery, chemotherapy, metabolism ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-03-31
    Description: This book includes useful and recent information to the readers regarding the following topics: Signs and symptoms and etiology and risk factors of head and neck cancer, Epidemiology and the role of microRNAs in nasopharyngeal carcinoma and oral carcinogenesis, History, classifications, and managements of salivary gland cancer, Considerations, classifications, and managements of thyroid gland cancer, Updates in the diagnosis and management of medullary thyroid carcinoma, Interventional techniques used for the relief of head and neck cancer pain, Oral side effects of head and neck irradiation, Health-related quality of life in maxillectomy patients rehabilitated with obturator prostheses
    Keywords: epidemiology, biomarker, chemotherapy, radiotherapy, micrornas, carcinoma ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-03-31
    Description: For the past two decades, the protein kinase family has been an intense area of research for developing anticancer drugs. Despite tremendous advancements in kinase drug expansion, many kinases are still unexplored. As such, this book includes research and review articles from experts that focus on protein kinase signalling pathways as a molecular drug target. Chapters include illustrations and cover such topics as the mechanism of action and anticancer activity of protein kinase inhibitors on various cancer types. They also discuss new opportunities, challenges, and future perspectives in the field.
    Keywords: toxicity, targeted therapy, drug resistance, clustering, inhibitor, cancer therapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-03-31
    Description: This book is a feast of knowledge, yet a balanced diet of healthy foods. There are high values of rich essential nutrients from top-quality medical research. But they are made easily digestible and absorbable, even by health care providers and planners, working in resource-limited settings, in all parts of the world, through social implications and community applications. All the chapters are value-added master pieces. The book would serve both as a scientific reference guide and a practical work manual. The authors, editor, and Intech publishers, together, are pleased to provide the readers a precious blend of scientific excellence and social relevance, for health empowerment, globally. We wish the readers great success, savoring science and sociology together.
    Keywords: cervical cancer, hpv, cancer, epidemiology, vaccine, colorectal cancer ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Solid Waste and Landfills Management - Recent Advances outlines the fundamental ideas and most recent developments for managing solid waste in an environmentally responsible manner. Globally, the quantity of solid trash is increasing, but its environmental impact is also a concern, especially with the advent of elements that are detrimental to ecosystems. This book examines all aspects of solid waste from a global perspective, including waste minimization, waste as a resource, proper disposal, and efficient systems promoted by sound public policy. It includes eight chapters written by eminent specialists that examine the essential topics to be considered during the various phases of a waste management program. Among the topics covered in this book are public policies focusing on reducing waste at its source, recycling, and minimizing disposal amounts; technologies for treating and recycling solid waste; safe, efficient treatment and disposal of hazardous and other special wastes; development and maintenance of engineered landfills and landfill mining; and legal frameworks and the use of life-cycle assessment as a tool for the waste management industry. This book is an indispensable resource for municipal engineers, environmental managers, researchers, students, policymakers, and planners interested in social and technological challenges connected to sustainable solid waste management.
    Keywords: environment ; energy ; biofuels ; ethanol ; recycling ; waste management ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNH Waste management
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: This book includes a selection of research work in the mobile robotics area, where several interesting topics are presented. In this way we find a review of multi-agents, different techniques applied to the navigation systems, artificial intelligence algorithms, which include deep learning applications, systems where a Kalman filter estimator is extended for visual odometry, and finally the design of an on-chip system for the execution of cognitive agents. Additionally, the development of different ideas in mobile robot applications are included and hopefully will be useful and enriching for readers.
    Keywords: machine learning, artificial intelligence, navigation, motion control, robot navigation, distributed control ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: The main purpose of control engineering is to steer the regulated plant in such a way that it operates in a required manner. The desirable performance of the plant should be obtained despite the unpredictable influence of the environment on the control system and no matter if the plant parameters are precisely known. Even though the parameters may change with time and load, still the system should preserve its nominal properties and ensure the required behavior of the plant. In other words, the principal objective of control engineering is to design systems that are robust with respect to external disturbances and modeling uncertainty. This objective may be very well achieved using the sliding mode technique, which is the subject of this book.
    Keywords: robust control, auv, microsoft flight simulatorr, uav predator, discrete time ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: This book presents an overview of Industry 4.0 (IR4.0) technologies including the Internet of Things (IoT), big data, data mining, deep learning, machine learning, Artificial Intelligence (AI), and cloud/edge computing. It also provides detailed insight into the impact of cutting-edge technologies such as the Internet of Services (IoS), innovative sensing strategies, and cyber-physical systems on IR4.0 as well as data-driven, real-time detection, and condition monitoring applications.
    Keywords: machine learning ; artificial intelligence ; deep learning ; internet of things ; cyber-physical systems ; big data ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: Robotic technology has increasingly been preferred by the medical professionals since they have been used for several clinical applications. Medical robots are preferred since they present better results compared to traditional methods such as smaller incision, higher accuracy, and lesser recovery time. Medical robots can be divided into three progressive generations. The first-generation robots were originally industrial robots that had been modified for performing medical applications in orthopedics, neurosurgery, radiology, and radiotherapy in the 1980s. The second-generation robots have been especially developed for executing surgical operations in the 1990s. After the 2000s, the third-generation medical robots have been designed for performing difficult surgical and medical operations. From the first approved surgical robot AESOP to the current da Vinci Surgical System, there have been several different kinds of surgical robots produced until now. Although the history of surgical robots is very short compared to the history of surgery, thousands of surgical robots have been installed in hospitals worldwide, and hundreds of thousands of people have been treated by these surgical robots. Nowadays, the achievements of the surgical robotics amaze both medical professionals and the patients. It is noteworthy to follow up on the evolution of surgical robotics in the future.
    Keywords: surgery, learning, hernia, oncology, robotic surgery, thyroidectomy ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Skin cancers, basal and squamous cell carcinomas, malignant melanomas, and Merkel cell carcinomas, constitute arguably the most common and increasingly prevalent human neoplasms. Here we discuss the epigenetic changes in DNA and chromatin, which are increasingly associated with melanoma. Several chapters focus on the posttranscriptional modification of the proteins at the melanocyte cell surface, their role in tumorigenesis, and their potential as therapeutic targets. Specifically, extracellular modifications of integrins, glycosylation of cell surface proteins, and changes of cadherins are presented. In a very interesting approach, a potential to target the mitochondria of melanoma cells is investigated. In conclusion, this volume presents various aspects of human skin cancers, components of the large worldwide effort to combat and eradicate this growing health concern.
    Keywords: melanoma, glycosylation, epigenetics, metastasis, cytotoxicity, migration ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2022-07-27
    Description: Though the treatment of central nervous system (CNS) tumors has been challenging, new advances have helped us better understand the molecular and genetic makeup of many tumor types, and new chemotherapies and immunotherapies have extended survival in patients with aggressive primary CNS tumors. This book discusses pediatric and adult tumors of the CNS, the classification schemes used to categorize them, advances in surgical techniques, and several important genetic alterations found in these tumors. We hope this book contributes to the reader’s understanding of these tumors and provides the most up-to-date and cutting-edge discoveries in this exciting field.
    Keywords: Oncology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Brain tumors comprise a spectrum of histological patterns. Their presentation and management depend on their location, size, and grade of lesions. This book is a collection of high-quality research work from global experts on brain tumors, including meningiomas, and their treatment.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Oral cancer is a common disease with a high incidence of morbidity and mortality. Despite technological advancements in diagnosis and treatment, the five-year survival rate is low. Researchers worldwide are attempting to identify new and novel methods for early diagnosis and better treatment of oral cancer to improve survival rate and quality of life post recovery. This book examines current concepts in oral cancer and emphasizes future perspectives for diagnosis and treatment of disease for better clinical outcomes and patient care.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: The portfolio diversification strategy study is useful to help investors to plan for the best investment strategy in maximizing return with the given level of risk or minimizing risk. Further, a new set of generalized sufficient conditions for the existence and uniqueness of the solution and finite-time stability has been achieved by using Generalized Gronwall-Bellman inequality. Moreover, a novel development is proposed to solve classical control theory’s difference diagrams and transfer functions. Advanced TCP strategies and free parametrization for continuous-time LTI systems and quality of operation of control systems are presented.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    IntechOpen | IntechOpen
    Publication Date: 2022-07-27
    Description: Hepatocellular carcinoma (HCC) represents one of the most significant global health issues, given its high prevalence and the challenging nature and physiology of the liver and hepatic surgery, in its many forms. This means that the most appropriate management for HCC should incorporate a multidisciplinary approach, combining the expertise from several different specialties. This book showcases the various steps in the development, diagnosis, staging, and management of HCC and provides views and thoughts from true experts in the field. As such, it is a useful resource for any physician or surgeon, whether training or practicing, who is interested in caring for patients with HCC.
    Keywords: Oncology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2022-07-27
    Description: Lymphoma is a group of malignant diseases caused by the clonal proliferation of lymphocytes. Current treatment options include chemotherapy, radiotherapy, and bone marrow/stem cell transplantation. Development of new treatment options for cancer medications include small molecules and monoclonal antibodies for immunotherapy. In addition, the discovery of new phytochemical agents used in complementary and alternative medicine adds perspective to the treatment of lymphoma. This book highlights recent developments in the treatment of lymphoma. Chapters discuss different types of lymphomas, such as follicular lymphoma, gastrointestinal lymphoma, splenic B-cell lymphoma, and others, as well as the available treatment options for each.
    Keywords: Oncology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: The purpose of this volume is to encourage and inspire the continual invention of robot manipulators for science and the good of humanity. The concepts of artificial intelligence combined with the engineering and technology of feedback control, have great potential for new, useful and exciting machines. The concept of eclecticism for the design, development, simulation and implementation of a real time controller for an intelligent, vision guided robots is now being explored. The dream of an eclectic perceptual, creative controller that can select its own tasks and perform autonomous operations with reliability and dependability is starting to evolve. We have not yet reached this stage but a careful study of the contents will start one on the exciting journey that could lead to many inventions and successful solutions.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-03-31
    Description: A multidisciplinary understanding of the various processes leading to colorectal cancer progression is important for creating promising methods of therapy. Therefore it is necessary to scrutinize the progression of cancer and the therapeutic process through various academic theories. This book examines colorectal cancer - its prevention, pathogenesis, and treatment - through a multidisciplinary lens in an effort to advance understanding of the disease and improve therapeutic efficacy.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: This book represents the contributions of the top researchers in the field of robotics, automation and control and will serve as a valuable tool for professionals in these interdisciplinary fields. It consists of 25 chapter that introduce both basic research and advanced developments covering the topics such as kinematics, dynamic analysis, accuracy, optimization design, modelling , simulation and control. Without a doubt, the book covers a great deal of recent research, and as such it works as a valuable source for researchers interested in the involved subjects.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: To design a team of robots which is able to perform given tasks is a great concern of many members of robotics community. There are many problems left to be solved in order to have the fully functional robot team. Robotics community is trying hard to solve such problems (navigation, task allocation, communication, adaptation, control, ...). This book represents the contributions of the top researchers in this field and will serve as a valuable tool for professionals in this interdisciplinary field. It is focused on the challenging issues of team architectures, vehicle learning and adaptation, heterogeneous group control and cooperation, task selection, dynamic autonomy, mixed initiative, and human and robot team interaction. The book consists of 16 chapters introducing both basic research and advanced developments. Topics covered include kinematics, dynamic analysis, accuracy, optimization design, modelling, simulation and control of multi robot systems.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: Factory automation has evolved significantly in the last few decades, and is today a complex, interdisciplinary, scientific area. In this book a selection of papers on topics related to factory automation is presented, covering a broad spectrum, so that the reader may become familiar with the various fields, and also study them in more depth where required. Within various chapters in this book, special attention is given to distributed applications and their use of networks, since it is one of the most relevant subjects in the evolution of factory automation. Different Medium Access Control and networks are analyzed, while Ethernet and Wireless networks are looked at in more detail, since they are among the hottest topics in recent research. Another important subject is everything concerning the increase in the complexity of factory automation, and the need for flexibility and interoperability. Finally the use of multi-agent systems, advanced control, formal methods, or the application in this field of RFID, are additional examples of the ideas and disciplines that experts around the world have analyzed in their work.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-03-31
    Description: “Gynaecological Malignancies - Updates and Advances” aims to present a review of the significant advances in the understanding and management of gynaecological malignancies. Major areas of importance in this field will be covered, incorporating new knowledge that has arisen due to the advancements in molecular techniques and the ability to correlate these molecular changes with clinical behaviour of gynaecologic tumours. The therapeutic implications of molecular subtyping to match appropriate therapies and the appreciation of the use of up to date radiotherapy techniques will be explored.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Publication Date: 2024-03-31
    Description: This book provides an excellent overview of how melanoma is treated in the clinic. Since oncologists and clinicians across the globe contributed to this book, each area also explores the unique burdens that geographical areas experience from melanoma subtypes and how these are treated in different settings. It also includes several chapters that illustrate novel methods for diagnosing melanoma in the clinic using new technologies, which are likely to significantly improve outcomes. Several chapters cover surgical techniques and other present very rare or challenging clinical cases of melanoma and how these were treated. The book is geared towards informing clinicians and even patients how melanoma arises, what tools are available and which decisions need to be made by patients and their families in order to treat this devastating disease.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-04-11
    Description: Since the introduction of the first industrial robot Unimate in a General Motors automobile factory in New Jersey in 1961, robots have gained stronger and stronger foothold in the industry. In the meantime, robotics research has been expanding from fix based robots to mobile robots at a stunning pace. There have been significant milestones that are worth noting in recent decades. Examples are the octopus-like Tentacle Arm developed by Marvin Minsky in 1968, the Stanford Cart crossing a chair-filled room without human assistance in 1979, and most recently, humanoid robots developed by Honda. Despite rapid technological developments and extensive research efforts in mobility, perception, navigation and control, mobile robots still fare badly in comparison with human abilities. For example, in physical interactions with subjects and objects in an operational environment, a human being can easily relies on his/her intuitively force-based servoing to accomplish contact tasks, handling and processing materials and interacting with people safely and precisely. The intuitiveness, learning ability and contextual knowledge, which are natural part of human instincts, are hard to come by for robots. The above observations simply highlight the monumental works and challenges ahead when researchers aspire to turn mobile robots to greater benefits to humankinds. This book is by no means to address all the issues associated mobile robots, but reports current states of some challenging research projects in mobile robotics ranging from land, humanoid, underwater, aerial robots, to rehabilitation.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: Model Predictive Control (MPC) usually refers to a class of control algorithms in which a dynamic process model is used to predict and optimize process performance, but it is can also be seen as a term denoting a natural control strategy that matches the human thought form most closely. Half a century after its birth, it has been widely accepted in many engineering fields and has brought much benefit to us. The purpose of the book is to show the recent advancements of MPC to the readers, both in theory and in engineering. The idea was to offer guidance to researchers and engineers who are interested in the frontiers of MPC. The examples provided in the first part of this exciting collection will help you comprehend some typical boundaries in theoretical research of MPC. In the second part of the book, some excellent applications of MPC in modern engineering field are presented. With the rapid development of modeling and computational technology, we believe that MPC will remain as energetic in the future.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-04-11
    Description: Despite the great technological advancement experienced in recent years, Programmable Logic Controllers (PLC) are still used in many applications from the real world and still play a central role in infrastructure of industrial automation. PLC operate in the factory-floor level and are responsible typically for implementing logical control, regulatory control strategies, such as PID and fuzzy-based algorithms, and safety logics. Usually PLC are interconnected with the supervision level through communication network, such as Ethernet networks, in order to work in an integrated form. In this context, this book was written by professionals that work and research in automation area and it has two major objectives. The first objective is present some advances in methodologies and techniques for development of industrial programs based on PLC. The second objective is present some PLC-based real applications from various areas such as manufacturing system, robotics, power system, communication system, and education.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: Skin cancers are the fastest growing type of cancer in the United States and represent the most commonly diagnosed malignancy, surpassing lung, breast, colorectal and prostate cancer. In Europe, the British Isles have been the highest rates of skin cancer in children and adolescents. The overall idea of this book is to provide the reader with up to date information on the possible tools to use for prevention, diagnosis and treatment of skin cancer. Three main issues are discussed: risk factors, new diagnostic tools for prevention and strategies for prevention and treatment of skin cancer using natural compounds or nano-particle drug delivery and photodynamic therapy.
    Keywords: Oncology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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    Publication Date: 2024-04-11
    Description: The book presents an excellent overview of the recent developments in the different areas of Robotics, Automation and Control. Through its 24 chapters, this book presents topics related to control and robot design; it also introduces new mathematical tools and techniques devoted to improve the system modeling and control. An important point is the use of rational agents and heuristic techniques to cope with the computational complexity required for controlling complex systems. Through this book, we also find navigation and vision algorithms, automatic handwritten comprehension and speech recognition systems that will be included in the next generation of productive systems developed by man.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-03-31
    Description: Hematology encompasses the physiology and pathology of blood and of the blood-forming organs. In common with other areas of medicine, the pace of change in hematology has been breathtaking over recent years. There are now many treatment options available to the modern hematologist and, happily, a greatly improved outlook for the vast majority of patients with blood disorders and malignancies. Improvements in the clinic reflect, and in many respects are driven by, advances in our scientific understanding of hematological processes under both normal and disease conditions. Hematology - Science and Practice consists of a selection of essays which aim to inform both specialist and non-specialist readers about some of the latest advances in hematology, in both laboratory and clinic.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-04-11
    Description: This book is the result of inspirations and contributions from many researchers worldwide. It presents a collection of wide range research results of robotics scientific community. Various aspects of current research in robotics area are explored and discussed. The book begins with researches in robot modelling & design, in which different approaches in kinematical, dynamical and other design issues of mobile robots are discussed. Second chapter deals with various sensor systems, but the major part of the chapter is devoted to robotic vision systems. Chapter III is devoted to robot navigation and presents different navigation architectures. The chapter IV is devoted to research on adaptive and learning systems in mobile robots area. The chapter V speaks about different application areas of multi-robot systems. Other emerging field is discussed in chapter VI - the human- robot interaction. Chapter VII gives a great tutorial on legged robot systems and one research overview on design of a humanoid robot.The different examples of service robots are showed in chapter VIII. Chapter IX is oriented to industrial robots, i.e. robot manipulators. Different mechatronic systems oriented on robotics are explored in the last chapter of the book.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2024-03-31
    Description: Colorectal cancer is a common disease, affecting millions worldwide and represents a global health problem. Effective therapeutic solutions and control measures for the disease will come from the collective research efforts of clinicians and scientists worldwide. This book presents the current status of the strides being made to understand the fundamental scientific basis of colorectal cancer. It provides contributions from scientists, clinicians and investigators from 20 different countries. The four sections of this volume examine the evidence and data in relation to genes and various polymorphisms, tumor microenvironment and infections associated with colorectal cancer. An increasingly better appreciation of the complex inter-connected basic biology of colorectal cancer will translate into effective measures for management and treatment of the disease. Research scientists and investigators as well as clinicians searching for a good understanding of the disease will find this book useful.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Publication Date: 2024-04-11
    Description: Biped robots represent a very interesting research subject, with several particularities and scope topics, such as: mechanical design, gait simulation, patterns generation, kinematics, dynamics, equilibrium, stability, kinds of control, adaptability, biomechanics, cybernetics, and rehabilitation technologies. We have diverse problems related to these topics, making the study of biped robots a very complex subject, and many times the results of researches are not totally satisfactory. However, with scientific and technological advances, based on theoretical and experimental works, many researchers have collaborated in the evolution of the biped robots design, looking for to develop autonomous systems, as well as to help in rehabilitation technologies of human beings. Thus, this book intends to present some works related to the study of biped robots, developed by researchers worldwide.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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    Publication Date: 2022-01-31
    Description: This book points to some new areas for investigation on squamous cell carcinoma (SCC). Firstly, the features and management of some specific SCC is discussed to give the readers the general principles in dealing with these uncommon and sophisticated conditions. Some new concepts in adjuvant therapy including neoadjuvant therapy and gold nanoparticle-based photo dynamic therapy are introduced. Secondly, a detailed discussion of molecular aspects of tumor invasion and progression in SCC is provided with the emphasis on the roles of some important factors. The role of tumor microenvironment in head and neck SCC is specifically discussed. Thirdly, the roles of cancer stem cells (CSC) in cancer therapy of SCC are described. Molecular mechanisms involving therapeutic resistance and new therapeutic strategies targeting CSC are discussed in detail. Finally, other aspects concerning SCC are included, which involve the assessment, genetic manipulation and its possible clinical implications for the treatment of SCC.
    Keywords: Oncology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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    Publication Date: 2024-04-11
    Description: Humanoid robots are developed to use the infrastructures designed for humans, to ease the interactions with humans, and to help the integrations into human societies. The developments of humanoid robots proceed from building individual robots to establishing societies of robots working alongside with humans. This book addresses the problems of constructing a humanoid body and mind from generating walk patterns and balance maintenance to encoding and specifying humanoid motions and the control of eye and head movements for focusing attention on moving objects. It provides methods for learning motor skills and for language acquisition and describes how to generate facial movements for expressing various emotions and provides methods for decision making and planning. This book discusses the leading researches and challenges in building humanoid robots in order to prepare for the near future when human societies will be advanced by using humanoid robots.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
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  • 92
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: This book titled Advances in Malignant Melanoma - Clinical and Research Perspectives represents an international effort to highlight advances in our understanding of malignant melanoma from both clinical and research perspectives. The authors for this book consist of an international group of recognized leaders in melanoma research and patient care, and they share their unique perspectives regarding melanoma epidemiology, risk factors, diagnostic and prognostic tools, phenotypes, treatment, and future research directions. The book is divide into four sections: (1) Epidemiology and Risk Factors of Melanoma, (2) Clinical Phenotypes of Melanoma, (3) Investigational Treatments for Melanoma and Pigmentary Disorders, and (4) Advances in Melanoma Translational Research. This book does not attempt to exhaustively cover all aspects of the aforementioned topics. Rather, it is a compilation of our authors' pearls and unique perspectives on the relevant advances in melanoma during the recent years.
    Keywords: Oncology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 93
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: In this book the variety of humanoid robotic research can be obtained. This book is divided in four parts: Hardware Development: Components and Systems, Biped Motion: Walking, Running and Self-orientation, Sensing the Environment: Acquisition, Data Processing and Control and Mind Organisation: Learning and Interaction. The first part of the book deals with remarkable hardware developments, whereby complete humanoid robotic systems are as well described as partial solutions. In the second part diverse results around the biped motion of humanoid robots are presented. The autonomous, efficient and adaptive two-legged walking is one of the main challenge in humanoid robotics. The two-legged walking will enable humanoid robots to enter our environment without rearrangement. Developments in the field of visual sensors, data acquisition, processing and control are to be observed in third part of the book. In the fourth part some "mind building" and communication technologies are presented.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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  • 94
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    IntechOpen | IntechOpen
    Publication Date: 2022-01-31
    Description: The book "Intraepithelial neoplasia" is till date the most comprehensive book dedicated entirely to preinvasive lesions of the human body. Created and published with an aim of helping clinicians to not only diagnose but also understand the etiopathogenesis of the precursor lesions, the book also attempts to identify its molecular and genetic mechanisms. All of the chapters contain a considerable amount of new information, with an updated bibliographical list as well as the latest WHO classification of intraepithelial lesions that has been included wherever needed. The text has been updated according to the latest technical advances.This book can be described as concise, informative, logical and useful at all levels discussing thoroughly the invaluable role of molecular diagnostics and genetic mechanisms of the intraepithelial lesions. To make the materials easily digestive, the book is illustrated with colorful images.
    Keywords: Oncology ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 95
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Vibrations are a part of our environment and daily life. Many of them are useful and are needed for many purposes, one of the best example being the hearing system. Nevertheless, vibrations are often undesirable and have to be suppressed or reduced, as they may be harmful to structures by generating damages or compromise the comfort of users through noise generation of mechanical wave transmission to the body. the purpose of this book is to present basic and advanced methods for efficiently controlling the vibrations and limiting their effects. Open-access publishing is an extraordinary opportunity for a wide dissemination of high quality research. This book is not an exception to this, and I am proud to introduce the works performed by experts from all over the world.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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  • 96
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: This book book is a collection of 18 chapters written by internationally recognized experts and well-known professionals of the field. Chapters contribute to diverse facets of contemporary robotics and autonomous systems. The volume is organized in four thematic parts according to the main subjects, regarding the recent advances in the contemporary robotics. The first thematic topics of the book are devoted to the theoretical issues. This includes development of algorithms for automatic trajectory generation using redudancy resolution scheme, intelligent algorithms for robotic grasping, modelling approach for reactive mode handling of flexible manufacturing and design of an advanced controller for robot manipulators. The second part of the book deals with different aspects of robot calibration and sensing. This includes a geometric and treshold calibration of a multiple robotic line-vision system, robot-based inline 2D/3D quality monitoring using picture-giving and laser triangulation, and a study on prospective polymer composite materials for flexible tactile sensors. The third part addresses issues of mobile robots and multi-agent systems, including SLAM of mobile robots based on fusion of odometry and visual data, configuration of a localization system by a team of mobile robots, development of generic real-time motion controller for differential mobile robots, control of fuel cells of mobile robots, modelling of omni-directional wheeled-based robots, building of hunter- hybrid tracking environment, as well as design of a cooperative control in distributed population-based multi-agent approach. The fourth part presents recent approaches and results in humanoid and bioinspirative robotics. It deals with design of adaptive control of anthropomorphic biped gait, building of dynamic-based simulation for humanoid robot walking, building controller for perceptual motor control dynamics of humans and biomimetic approach to control mechatronic structure using smart materials.
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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  • 97
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: During the last decades, numerous studies about stem cells and regenerative medicine highlighted new therapeutic approaches to treat several neurological disorders. It is noteworthy that the current optimism over potential stem cell therapies is driven by new understandings of stem cell biology leading to specific cell fate decision. The objectives of this book were: 1) to offer a general understanding of signaling pathways underlying the capacity of differentiation of several types of stem cells into neurons, during the development; 2) to understand how those pathways are altered in pathological conditions; 3) to describe advances in cellular therapy that could be use to restore central nervous system dysfunction in pathological conditions.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 98
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: In spite of advances in the cancer research field, cancer treatment still challenges researchers and clinicians, as proven by the still impressive and increasing number of worldwide cancer-related deaths. Updates on Cancer Treatment is an attempt to integrate into a book volume various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 99
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book offers significant coverage on different aspects of cancer from risk factors to the mechanisms leading to tumor progression and metastasis. Although tremendous progress has been made in cancer research and treatment, cancer metastasis remains a major unmet clinical need. The life and death of many cancer patients hangs on the degree of metastasis. This book provides new perspectives for diagnosis and cancer therapy. It includes new technologies and a new basis for current cancer therapies. To guarantee the high quality of this book, important topics are included and rigorously discussed in a simple and authentic way. The book addresses important challenges governing tumor progression and metastasis and brings new responses to both diagnosis and therapy. This book is a great source of knowledge and will be useful for researchers, medical doctors, oncologists, graduate and medical students, continued medical educators, health care providers, and all individuals interested in understanding cancer and its challenges.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 100
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Frontiers of Model Predictive Control Robust Model Predictive Control Nonlinear Model Predictive Control Excellent Applications Guide for Researchers and Engineers Recent Achievements of Authors over the World Theory with Practical Examples Kinds of Algorithms for Choice
    Keywords: Automatic control engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering
    Language: English
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