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  • Books  (255)
  • Open Access  (144)
  • thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology  (102)
  • Cell & Developmental Biology
  • Chemical Engineering
  • Humans
  • Inorganic Chemistry
  • energy
  • Springer  (147)
  • IntechOpen  (105)
  • CRC Press
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  • 1
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: In the past decade, we have witnessed innovation in surgical treatment for renal cell carcinoma (RCC), including robotic platforms with integration of imaging approaches, and advances in targeted therapy, immunotherapy, and combination therapy to treat patients with advanced RCC. This book presents updated information on the epidemiology, genetics, diagnosis, screening, and advances in the treatment and management of RCC. It is a useful resource for any clinician involved in the management of patients with RCC, as well as other physicians, researchers, and patients.
    Keywords: immunotherapy ; genetics ; ultrasound ; mri ; targeted therapy ; epigenetic ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 2
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Pancreatic Cancer - Updates in Pathogenesis, Diagnosis and Therapies presents the most recent knowledge on pancreatic cancer, which is a deadly, challenging and catastrophic tumor with a high mortality rate. It is the seventh leading cause of cancer-related mortality worldwide. Pancreatic cancer can be diagnosed clinically, by laboratory measures, by imaging, and by pathological detection. Understanding tumor pathogenesis as well as tumor risk factors is necessary for successful treatment, as is early detection and multidisciplinary treatment. This book provides a comprehensive overview of pancreatic cancer in four sections. Chapters address such topics as prevention, screening, and detection; pathogenesis and risk factors; and pathology and management.
    Keywords: pancreas ; obesity ; epidemiology ; risk factors ; screening ; pathology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 3
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-07
    Description: This book offers a comprehensive overview of recent developments in the field of obesity. The chapters are authored by prominent scholars in the field with direct knowledge, through practice and research, of the real-world problems associated with obesity. Chapters address such topics as obesity in children, stigmatization of people with obesity, metabolic effects of obesity, recent advances in pharmacology and surgical interventions for obesity, and more.
    Keywords: inflammation ; oxidative stress ; energy ; metabolism ; neurodegeneration ; leptin ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJG Endocrinology
    Language: English
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  • 4
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book offers outstanding approaches to understanding the role of the tumor microenvironment (TME) in cancer development and metastasis. The TME, with its multifaced role, is fundamental in the control and exacerbation of almost all cancer types. The outcome of many solid tumors is dependent on the modulation of the TME. Local tumor immunity, which is crucial in the control of cancer promotion, is one of the leading compounds of the TME. This book presents new insights and provides detailed and updated descriptions of the role of the TME in the control and the development of almost all cancer types. This book is an authentic source of knowledge, useful for researchers, medical doctors, students, and all individuals interested in understanding the mechanisms of cancer control and development.
    Keywords: cancer ; metabolism ; lung cancer ; nutrients ; minimally invasive surgery ; liquid biopsy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 5
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book describes and discusses numerous new concepts and procedures for the diagnosis and management of all types of neurofibromatosis (NF). It includes five chapters that address numerous topics in the field, including the management of toxicities associated with NF treatment modalities. It provides useful information and data for both researchers and practitioners to develop new approaches for the management of NF.
    Keywords: Neurofibromatosis 1 ; Schwannomatosis ; Risk Factors ; Neurofibromatosis 2 ; Epidemiology ; Diagnosis ; Cancer Therapies ; Physiological Dysfunction ; Chemotherapy ; Surgery ; Monitoring ; Gene Immunotherapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 6
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Green computing involves developing, designing, engineering, producing, using, and disposing of computing modules and devices to reduce environmental hazards and pollution. Green computing technologies are crucial for protecting the planet from environmental hazards and pollution. This book presents new subjects and innovations in green computing technologies and in green computing and electronics industries. Chapters address such topics as green wearable sensors, variable renewable energy, managing energy consumption using the Internet of Things (IoT) and big data, using forest waste to produce biofuel and biodiesel, green computing in ophthalmological practice, and much more.
    Keywords: agriculture ; renewable energy ; biodiversity ; energy ; big data ; iot ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQD Environmental monitoring
    Language: English
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  • 7
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Solar energy is a significant renewable energy source that is abundant and environmentally friendly. Solar PV Panels – Recent Advances and Future Prospects provides a comprehensive overview of solar photovoltaic (PV) panels for direct electric power production. Chapters address such topics as fundamentals of solar PV panels; modeling, simulations, optimization, and economics of solar panels; solar panels testing; semiconductor materials for solar cells and panels; solar PV applications and policies; and solar PV and battery storage sizing for stand-alone and grid-connected applications.
    Keywords: solar cells ; renewable energy ; energy ; cfd ; 2d materials ; solar energy ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THV Alternative and renewable energy sources and technology
    Language: English
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  • 8
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book provides a comprehensive overview of multiple myeloma. It is organized into three sections with chapters addressing topics such as diagnosis, risk stratification, and management of multiple myeloma; treatment of multiple myeloma at diagnosis and at relapse; management of disease complications; and stem cell therapies, including autologous and allogeneic hematopoietic stem cell transplantation with a focus on autologous grafting using non-cryopreserved stem cells and performance of stem cell transplantation in outpatient settings.
    Keywords: cryopreservation ; chemotherapy ; quality of life ; hematopoietic stem cell transplantation ; monoclonal antibodies ; adverse effects ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 9
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: There are many different types of cancer. Some are very common; others are rare. Having some similar features, each cancer has its own characteristics and symptoms, which vary according to the type of cancer and where it is in the body. The treatment selected may be influenced by the patient's age, concurrent health problems, life expectancy, characteristics of the individual's cancer, the patient's goals of treatment, and the bias of the treating physician. In preparing this book, we have considered and reflected on the concept of the recent advances in cancer management and therapy as well as molecular applications in cancer therapy. The readers can find detailed information about the treatment and management of specific cancers in these book chapters.
    Keywords: breast cancer, immunotherapy, apoptosis, colorectal cancer, lung cancer, targeted therapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 10
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book covers specific chapters with fundamental and current concepts about the main primary intracranial tumors, aimed at general neurosurgeons, neurologists, oncologists, radiotherapists, and residents. They are everyday situations from the subspecialist routine that can become challenging for professionals outside referenced centers or working alone.
    Keywords: glioblastoma, magnetic resonance imaging, gliomas, immunotherapy, biomarker, chemotherapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 11
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: The current volume entitled, "Free Radicals and Diseases" integrates knowledge in free radical-associated diseases from the basic level to the advanced level, and from the bench side to bed side. The chapters in this book provide an extensive overview of the topic, including free radical formations and clinical interventions.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 12
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Pancreatic cancer is one of the most lethal solid organ tumors with a poor five-year survival rate despite current oncological advances. The early and proper diagnosis of pancreatic cancer is of great importance for the improvement of the overall prognosis. This book provides an overview of the current challenges and states of pancreatic cancer and pancreatic neuroendocrine tumors, including information on diagnostic tools, treatment strategies, and mechanisms of pancreatic cancer therapy resistance.
    Keywords: immunotherapy, tumor microenvironment, irreversible electroporation, therapy, computer-assisted surgery ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 13
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Malnutrition is the specific condition produced by the intake of too few macronutrients, too many macronutrients (obesity), or inordinate amounts of inappropriate substances such as alcohol. Globally, malnutrition is a major nutritional disorder, especially in developing economies. Poor dietary habits and imbalanced nutrient intake result in adverse consequences on normal body functionality. This book highlights the major causes of malnutrition and how to overcome this problem. Chapters address such topics as energy metabolism and balance, diagnosis of malnutrition, negative effects of malnutrition, sugar and its impact on health, malnutrition in the elderly and children, and much more.
    Keywords: public health ; undernutrition ; cancer ; inflammation ; energy ; metabolism ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine::MBNH Personal & public health::MBNH3 Dietetics & nutrition
    Language: English
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  • 14
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book entitled Cervical Cancer - Screening, Treatment and Prevention Universal Protocols for Ultimate Control is the fourth successful endeavor of the Editor with InTech publisher. The four books serve as four pillars in cervical cancer control, globally. This book is unique and sensational. Public health "topics" are assuming a status of "phenomenon," through deliberations and research. Screening is riddled with global limitations of availability, affordability, acceptability, and accessibility. The treatment of precancers has questionable efficiency. Prevention is costly with the inclusion of HPV vaccine. This book helps to find the solutions. The authors, editor, and InTech publisher wish the readers a pleasant and purposeful reading. This book is a "readers' feast," "receivers' choice," and "respondents' delight." Enjoy and treasure the international facts and flavors.
    Keywords: human papillomavirus, biomarker, microbiome, carcinogenesis, radiation, genetic variation ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 15
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viruses. These carcinogens can induce specific genetic and epigenetic alterations in these tissues, leading to aberrant functioning of oncogenes and tumor suppressor genes. On the microRNAs (miRNAs) there are significant modifiers of both transcription and translation of oncogenes in carcinogenesis. In the last 50 years, several oncogenes and microRNAs related to these oncogenes have been identified in different types of human cancers. It is now clear that high expression of oncogenes, DNA damage response, and regulation of the cell cycle are related to the circadian clock. This book will mainly focus on the expressions of different oncogenes in breast, colon, and lung cancers. Moreover, readers will gain qualified scientific knowledge of the alterations in miRNAs in different types of cancers and the effects of the circadian clock on the expression of oncogenes in carcinogenesis.
    Keywords: breast cancer, colorectal cancer, lung cancer, mirna, dna repair, arsenic ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 16
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Pheochromocytoma, paraganglioma and neuroblastoma are the most common neural crest-derived tumors in adults and children, respectively. These neoplasms are associated with significant morbidity and mortality. Some international studies currently underway are researching and evaluating the presence of any similarities and differences between these tumors. Hopefully, future results will reveal several potential novel genes and pathways that might have major roles in the pathogenesis and progression of these neoplasms. This book discusses epidemiology, genetics, and treatment of these malignancies.
    Keywords: chemotherapy, metastasis, mirna, dna methylation, epigenetic, laparoscopic surgery ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 17
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book discusses the application of bioinformatics in cancer disease management. It covers general aspects of cancer as a disease but also as a success story in the translation of omics data in clinical settings. It provides an overview of the specific applications of bioinformatics tools in cancer epidemiology, prevention, and screening and in the identification of novel genetic and molecular biomarkers involved in cancer development. This is accomplished through the inclusion of numerous examples of the use of bioinformatics in precision oncology.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 18
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Glioblastoma (GBM) is a common and aggressive brain cancer with features of necrosis and endothelial proliferation in the histopathologic examination. Its presentation and management depend on tumor location, size, grade, and underlying histopathological characteristics. GBM tumors have clinical features of increased intracranial pressure, focal neurological deficits, or seizures (generalized or partial) with rapid progression. This book discusses GBM and its diagnosis, treatment, and management.
    Keywords: immunotherapy ; chemotherapy ; glioma ; genetics ; biomarker ; elderly ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 19
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Hepatocellular carcinoma (HCC) currently ranks as the third most common cause of death. As the primary malignancy of the liver is directly related to an underlying liver condition, its incidence and profile are expected to change soon. While effective prevention programs and antiviral therapies for hepatitis B and C will lower the incidence of HCC, emerging socioeconomic issues will deliver new at-risk populations. Moreover, diagnostic techniques and protocols have undergone significant advancements. Reliance on contrast enhanced ultrasound has been re-evaluated, imaging methods being considered as sufficient diagnostic tools. Molecular characterization remains desirable, since chemotherapeutic agents still have limited applicability. In light of recent diagnostic advancements and novel therapeutic solutions, it is our belief that a comprehensive update on recent paradigm shifts and interesting upcoming developments is highly needed.
    Keywords: cancer, targeted therapy, obesity, immunotherapy, metabolism, microrna ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 20
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Metastasis is the major cause of cancer-related death. It is a multistep process. The mechanism underlying metastasis is complicated and poorly understood. Recent advances in tumor metastasis research have led to improved diagnosis and clinical management of cancer. However, new strategies on metastasis treatment are urgently needed, especially the novel biomarkers discovery and targeted therapy. This book is designed to present the most recent advances in tumor metastasis.
    Keywords: cancer, breast cancer, drug delivery, exosomes, extracellular matrix, ovarian cancer ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 21
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Melanoma is an aggressive type of cancer for which treatment has dramatically evolved during the last 15 years, improving response and survival figures. This book, written by a diverse panel of experts, presents a description of the most relevant aspects of the epidemiology, diagnosis, local treatment, prognostic biomarkers and treatment for advanced disease, including the most recent research on novel molecules that are either approved or are undergoing clinical development. It includes insights on such challenging topics as when immunotherapy should be started in BRAF mutant patients, or which is the most appropriate treatment algorithm in those cases, as well as how to handle difficult and poor-prognosis melanoma cases, such as patients with brain metastases or patients with the uveal disease.
    Keywords: immunotherapy ; targeted therapy ; histopathology ; cancer ; radiotherapy ; immune checkpoint inhibitors ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 22
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas.
    Keywords: biomarkers, immunotherapy, chemotherapy, melanoma, targeted therapy, squamous cell carcinoma ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 23
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a number of putative therapeutic targets, including signal transduction pathways, metabolic and epigenetic alterations in tumor cells, the tumor microenvironment, the gut microbiome, and functions of immune effector cells. Given the multi-step nature of most cancers, including HCC, future drug development will most likely require combination therapies that will simultaneously target multiple steps in hepatocarcinogenesis.
    Keywords: hepatocellular carcinoma ; liver cirrhosis ; inflammation ; biomarkers ; immunotherapy ; gene expression ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 24
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: This Edited Volume “Nanogenerators and Self-Powered Systems” is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of nanotechnology and nanomaterials. The book comprises single chapters authored by various researchers and edited by an expert active in harnessing the ubiquitously available biomechanical energies to power portable electronics research area. All chapters are complete in themselves but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on nanotechnology and nanomaterials and opening new possible research paths for further novel developments.
    Keywords: energy ; sensors ; mems ; solar energy ; solar cells ; photovoltaic ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THV Alternative and renewable energy sources and technology
    Language: English
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  • 25
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Recent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin’s drug resistance and critical side effects.
    Keywords: immunotherapy, doxorubicin, cancer immunotherapy, cancer, optimization, nanoparticles ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 26
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book deals with the rapid progress in the area of myelodysplastic syndromes (MDS). MDS are a group of age-associated heterogeneous malignant bone marrow stem cell disorders. MDS are characterized by ineffective hematopoiesis, which leads to refractory cytopenias and to clonal instability. Patients with MDS have myeloid dysplasia, intramedullary apoptosis and an increased risk of transformation to acute myeloid leukemia (AML). The use of next generation sequencing has allowed for the identification of molecular mutations in several genes in about 90% of MDS patients. Several mutations will likely be incorporated into future prognostic scoring systems for MDS. About 50% of MDS cases are characterized by the presence of cytogenetic abnormalities. The correct morphological and cytogenetic analysis interpretation plays an important role in diagnosis and prognosis of these disorders. Cell death and an inflammatory gene signature are associated with MDS. Better understanding of the genetic and molecular mechanisms of MDS pathogenesis provides an opportunity for new treatment strategies to be developed. Promising novel therapies targeting pathophysiological mechanisms of MDS are being studied but the drugs currently used in MDS therapy remain limited. The only curative therapy for MDS is allogeneic hematopoietic stem cell transplantation. Recent advances in strategies to minimize transplant-related toxicity make this treatment possible for more MDS patients who are sufficiently fit.
    Keywords: cytokines, pathogenesis, micrornas, dendritic cells, behçet’s disease, vasculitis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 27
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book is a comprehensive overview of the recent developments in the clinical and research fields of multiple myeloma. It is divided into three main sections that cover a wide range of topics, including: epidemiology and pathogenesis of the disease, genetic targets and pathways, resistance to novel therapies, angiogenesis and anti-angiogenesis, hematopoietic stem cell transplantation, role of radiology and radiotherapy in myeloma, infectious complications, and management of multiple myeloma in resource-poor countries.
    Keywords: hematopoietic stem cell transplantation, monoclonal antibodies, novel therapies, epidemiology, risk factors, angiogenesis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 28
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book aims to foster collaboration between world-class bench scientists and clinicians in the fields of oncology, surgery, and pathology as they come together to highlight the complexity and diversity of soft tissue tumors as well as recent advances in their diagnosis and clinical management.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 29
    Publication Date: 2024-03-31
    Description: The aim of this book is to provide an overview of the importance of exosomes in the biomedical field, which involves in novel implications of exosomes in diagnosis and treatment of cancer and infectious diseases. The book would definitely be an ideal source of scientific information of exosomes to researchers and scientists involved in biomedicine, biology, and other areas involving cancer and infectious diseases.
    Keywords: biomarkers, extracellular vesicles, pathogenesis, multiple myeloma, liquid biopsy, endothelial cells ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 30
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Carbon Nanotubes - Recent Advances, New Perspectives and Potential Applications covers all the important nanotechnological aspects of carbon materials, including their growth and characterization, processing and fabrication, development and potential applications. Recent developments, innovative preparation methods and promising new frontiers around this advanced nanotechnology are reviewed under the editorship of an internationally renowned scientist. This book will be useful to a diverse range of readers and will be important for research organizations, government research centers, academic libraries, and those involved in the research and development of carbon materials.
    Keywords: nanoparticles ; nanocomposites ; energy ; wastewater treatment ; nanofibers ; conductivity ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 31
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Lung cancer continues to be the leading cause of cancer mortality worldwide among both men and women. Recent advances in prevention, screening and management in the past decade have led to significant improvements in survival and quality of life. Local treatments like minimally invasive surgery, radiotherapy, and image-guided ablation have contributed to improving the effectiveness and tolerability of potentially curative treatments in early-stage, locally advanced, and oligometastatic/oligoprogressive disease. Chemotherapy, targeted therapy, immunotherapy, and palliative local therapy options have expanded rapidly, with new regimens showing improved outcomes even for those with widely metastatic disease. This book comprehensively reviews the evidence that has driven personalized medicine, based on a variety of multidisciplinary perspectives by international lung cancer experts.
    Keywords: minimally invasive surgery, robotic surgery, immunotherapy, radiotherapy, mirna, liquid biopsy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 32
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Cancer mortality and morbidity are primarily brought on by metastasis. The ability of neoplastic cells to spread and colonize distant tissues is their most dangerous trait. Most malignancies are curable when they are detected early and have not spread outside of the original tissue. However, cancer is frequently incurable when tumor cells have created colonies elsewhere. Thus, the book content This book provides comprehensive information on cancer metastasis, along with references to specific cancer cases. The topics discussed include invasion by perturbation of cell-cell and cell-matrix adhesion, matrix degradation, motility, intravasation, extravasation, metastatic colonization, metastasis and angiogenesis. Molecular mechanisms, the metastatic process, and palliative bone metastasis therapy are also considered.
    Keywords: breast cancer ; immunotherapy ; epigenetics ; lung cancer ; extracellular vesicles ; targeted therapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Among the deadliest type of cancers, lung cancer faces several challenges in diagnosis and treatment: late diagnosis and misdiagnosis, inadequate tumor sampling, and resistance development to current therapies, among others. Together with advances in the understanding of molecular features, factors, and mechanisms involved in initiation and tumor progression, important improvements have occurred in diagnostics and therapeutics in the shape of advances in molecular genotyping, procedures for sampling, new potential, and less invasive sources of samples for the diagnosis and development of new targeted therapies. The aim of this book is to provide an exciting read on strategies in the diagnosis and therapy of lung cancer.
    Keywords: immunotherapy, biomarker, metabolomics, epigenetic, cancer stem cells, methylation ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Corals have thrived on the bottom of the ocean for millions of years. These fascinating animals are currently forced to cope with the rapid changes caused by humans to avoid extinction. How are corals changing their way of processing energy from different sources? What do we know about the corals living in the unseen depths of certain seamounts? What is the impact of oil spills and what can we do? How are coral reefs all over the world to be restored? What is the socioeconomic importance of these habitats, and what do we gain or lose with their survival or their demise? By involving scientists and conservationists from different areas of the world, this book answers these and other questions about corals, the habitat they form, and the influence that we have on them.
    Keywords: climate change ; conservation ; energy ; bioremediation ; metabolism ; probiotics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSP Hydrobiology::PSPM Marine biology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Human life relies on two basic supplies from nature: oxygen and food. Oxygen can be utilized directly, but food has to go through a process of digestion to become usable nutrients. The esophagus represents the beginning of this long journey. Because of its critical location, esophageal cancer is one of the deadliest malignancies in the world, and furthermore its incidence has been rising steadily year after year while other cancers are declining. It is predicted that by the year 2035 the esophageal cancer population will increase by 77.4% and become one of top global concerns. This book covers many aspects of esophageal cancer, through which we hope to raise the awareness of professionals as well as non-professionals about this disease.
    Keywords: immunotherapy, regenerative medicine, tumor microenvironment, gerd, laryngectomy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: In this book the reader will find a collection of chapters written by different research teams describing different aspects of peripheral T-cell lymphoma pathobiology, classification, and treatment. This work is mainly addressed to researchers already working in this area, but it is also accessible to anyone with a scientific background who desires to have an updated overview of the recent progress in this domain. It will also be valuable to scientists and physicians who have become newly involved in this field. Each chapter is self-contained and can be read independently of the others. This book intends to provide highlights of the current research as well as the current gold standards for diagnosis and treatment of these diseases, showing the recent advances in the personalized approach to T-cell derived lymphomas.
    Keywords: epigenetics, genomics, targeted therapy, precision medicine, transcriptomics, tyrosine kinase inhibitors ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Colorectal cancer is the third most common cancer diagnosed in both men and women worldwide. This book examines state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. It emphasizes the importance of a multidisciplinary approach involving multiple specialties, including surgery, gastroenterology, radiology, biology, oncology, radiotherapy, nuclear medicine, and physiotherapy.
    Keywords: colon cancer, immunotherapy, mri, targeted therapy, mortality, imaging ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: An understanding of the molecular pathogenesis of colorectal cancer by researchers and clinicians is essential to facilitate progress in improving patient outcomes in this common cancer that still carries a poor prognosis if not identified early. This book covers the major areas of importance in the field, incorporating new knowledge that has arisen due to the advancement of molecular techniques and the ability to correlate molecular changes with clinical behaviour of tumours. Each chapter is a summary written by experts, concisely summarising current data as well as highlighting potential areas for advancement. Appreciating the differences between tumours on a molecular level is the key to developing and delivering precision medicine, and nowhere is this more critically required than in the field of colorectal cancer.
    Keywords: epigenetics, biomarker, mass spectrometry, proteomics, dna methylation, personalized medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Neoplasm refers to an abnormal tissue growth that arises as a consequence of rapid cell proliferation and continues to grow abnormally even after terminating the stimuli that had instigated the change. It lacks partial or complete functional coordination with that of the normal tissues. Neoplasms are classified depending on the degree and type of tissues involved. Carcinogenesis is a multistep process where a plethora of endogenous and exogenous factors turns out genetic and epigenetic modifications, which collectively amend some critical cellular pathways controlling the proliferation, apoptosis, and differentiation. The cells having aberrant modifications are transformed into malignant ones of which the clonal expansion results in the development of cancer. This book provides the reader with a comprehensive overview of various cancer types along with their molecular mechanisms of initiation and progression. It also describes the current knowledge about the state-of-the-art measures being employed in cancer diagnosis and therapeutics. Particular attention is paid to make this book equally useful for students, practitioners, and expert scientists.
    Keywords: cancer, biomarkers, immunotherapy, surgery, chemotherapy, metabolism ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book includes useful and recent information to the readers regarding the following topics: Signs and symptoms and etiology and risk factors of head and neck cancer, Epidemiology and the role of microRNAs in nasopharyngeal carcinoma and oral carcinogenesis, History, classifications, and managements of salivary gland cancer, Considerations, classifications, and managements of thyroid gland cancer, Updates in the diagnosis and management of medullary thyroid carcinoma, Interventional techniques used for the relief of head and neck cancer pain, Oral side effects of head and neck irradiation, Health-related quality of life in maxillectomy patients rehabilitated with obturator prostheses
    Keywords: epidemiology, biomarker, chemotherapy, radiotherapy, micrornas, carcinoma ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: For the past two decades, the protein kinase family has been an intense area of research for developing anticancer drugs. Despite tremendous advancements in kinase drug expansion, many kinases are still unexplored. As such, this book includes research and review articles from experts that focus on protein kinase signalling pathways as a molecular drug target. Chapters include illustrations and cover such topics as the mechanism of action and anticancer activity of protein kinase inhibitors on various cancer types. They also discuss new opportunities, challenges, and future perspectives in the field.
    Keywords: toxicity, targeted therapy, drug resistance, clustering, inhibitor, cancer therapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book is a feast of knowledge, yet a balanced diet of healthy foods. There are high values of rich essential nutrients from top-quality medical research. But they are made easily digestible and absorbable, even by health care providers and planners, working in resource-limited settings, in all parts of the world, through social implications and community applications. All the chapters are value-added master pieces. The book would serve both as a scientific reference guide and a practical work manual. The authors, editor, and Intech publishers, together, are pleased to provide the readers a precious blend of scientific excellence and social relevance, for health empowerment, globally. We wish the readers great success, savoring science and sociology together.
    Keywords: cervical cancer, hpv, cancer, epidemiology, vaccine, colorectal cancer ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Solid Waste and Landfills Management - Recent Advances outlines the fundamental ideas and most recent developments for managing solid waste in an environmentally responsible manner. Globally, the quantity of solid trash is increasing, but its environmental impact is also a concern, especially with the advent of elements that are detrimental to ecosystems. This book examines all aspects of solid waste from a global perspective, including waste minimization, waste as a resource, proper disposal, and efficient systems promoted by sound public policy. It includes eight chapters written by eminent specialists that examine the essential topics to be considered during the various phases of a waste management program. Among the topics covered in this book are public policies focusing on reducing waste at its source, recycling, and minimizing disposal amounts; technologies for treating and recycling solid waste; safe, efficient treatment and disposal of hazardous and other special wastes; development and maintenance of engineered landfills and landfill mining; and legal frameworks and the use of life-cycle assessment as a tool for the waste management industry. This book is an indispensable resource for municipal engineers, environmental managers, researchers, students, policymakers, and planners interested in social and technological challenges connected to sustainable solid waste management.
    Keywords: environment ; energy ; biofuels ; ethanol ; recycling ; waste management ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNH Waste management
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Skin cancers, basal and squamous cell carcinomas, malignant melanomas, and Merkel cell carcinomas, constitute arguably the most common and increasingly prevalent human neoplasms. Here we discuss the epigenetic changes in DNA and chromatin, which are increasingly associated with melanoma. Several chapters focus on the posttranscriptional modification of the proteins at the melanocyte cell surface, their role in tumorigenesis, and their potential as therapeutic targets. Specifically, extracellular modifications of integrins, glycosylation of cell surface proteins, and changes of cadherins are presented. In a very interesting approach, a potential to target the mitochondria of melanoma cells is investigated. In conclusion, this volume presents various aspects of human skin cancers, components of the large worldwide effort to combat and eradicate this growing health concern.
    Keywords: melanoma, glycosylation, epigenetics, metastasis, cytotoxicity, migration ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 45
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    Springer Nature | Springer
    Publication Date: 2024-04-14
    Description: This open access book as one of the fastest-growing areas of research in machine learning, metalearning studies principled methods to obtain efficient models and solutions by adapting machine learning and data mining processes. This adaptation usually exploits information from past experience on other tasks and the adaptive processes can involve machine learning approaches. As a related area to metalearning and a hot topic currently, automated machine learning (AutoML) is concerned with automating the machine learning processes. Metalearning and AutoML can help AI learn to control the application of different learning methods and acquire new solutions faster without unnecessary interventions from the user. This book offers a comprehensive and thorough introduction to almost all aspects of metalearning and AutoML, covering the basic concepts and architecture, evaluation, datasets, hyperparameter optimization, ensembles and workflows, and also how this knowledge can be used to select, combine, compose, adapt and configure both algorithms and models to yield faster and better solutions to data mining and data science problems. It can thus help developers to develop systems that can improve themselves through experience. This book is a substantial update of the first edition published in 2009. It includes 18 chapters, more than twice as much as the previous version. This enabled the authors to cover the most relevant topics in more depth and incorporate the overview of recent research in the respective area. The book will be of interest to researchers and graduate students in the areas of machine learning, data mining, data science and artificial intelligence. ; Metalearning is the study of principled methods that exploit metaknowledge to obtain efficient models and solutions by adapting machine learning and data mining processes. While the variety of machine learning and data mining techniques now available can, in principle, provide good model solutions, a methodology is still needed to guide the search for the most appropriate model in an efficient way. Metalearning provides one such methodology that allows systems to become more effective through experience. This book discusses several approaches to obtaining knowledge concerning the performance of machine learning and data mining algorithms. It shows how this knowledge can be reused to select, combine, compose and adapt both algorithms and models to yield faster, more effective solutions to data mining problems. It can thus help developers improve their algorithms and also develop learning systems that can improve themselves. The book will be of interest to researchers and graduate students in the areas of machine learning, data mining and artificial intelligence.
    Keywords: Metalearning ; Automating Machine Learning (AutoML) ; Machine Learning ; Artificial Intelligence ; algorithm selection ; algorithm recommendation ; algorithm configuration ; hyperparameter optimization ; automating the workflow/pipeline design ; metalearning in ensemble construction ; metalearning in deep neural networks ; transfer learning ; algorithm recommendation for data streams ; automating data science ; Open Access ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence ; thema EDItEUR::U Computing and Information Technology::UN Databases::UNF Data mining ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence::UYQM Machine learning
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Brain tumors comprise a spectrum of histological patterns. Their presentation and management depend on their location, size, and grade of lesions. This book is a collection of high-quality research work from global experts on brain tumors, including meningiomas, and their treatment.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Oral cancer is a common disease with a high incidence of morbidity and mortality. Despite technological advancements in diagnosis and treatment, the five-year survival rate is low. Researchers worldwide are attempting to identify new and novel methods for early diagnosis and better treatment of oral cancer to improve survival rate and quality of life post recovery. This book examines current concepts in oral cancer and emphasizes future perspectives for diagnosis and treatment of disease for better clinical outcomes and patient care.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 48
    Publication Date: 2024-04-03
    Description: This book presents an up to date ethical framework for radiological protection in medicine. It is consistent with the requirements of the system of radiation protection and with the expectations of medical ethics. It presents an approach rooted in the medical tradition, and alert to contemporary social expectations. It provides readers with a practical framework against which they can assess the safety and acceptability of medical procedures, including patients’ concerns. It will be an invaluable reference for radiologists, radiation oncologists, regulators, medical physicists, technologists, other practitioners, as well as academics, researchers and students of radiation protection in medicine. Features: An authoritative and accessible guide, authored by a team who have contributed to defining the area internationally Includes numerous practical examples/clinical scenarios that illustrate the approach, presenting a pragmatic approach, rather than dwelling on philosophical theories Informed by the latest developments in the thinking of international organizations
    Keywords: Dosimetry;Health physics;Medical ethics;Morality in medicine;Radiation dose;Radiation risk ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKS Medical imaging::MKSH Medical imaging: radiology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Springer Nature | Springer
    Publication Date: 2022-03-16
    Description: This open access book presents original contributions and thought leadership on academic integrity from a variety of Canadian scholars. It showcases how our understanding and support for academic integrity have progressed, while pointing out areas urgently requiring more attention. Firmly grounded in the scholarly literature globally, it engages with the experience of local practicioners. It presents aspects of academic integrity that is specific to Canada, such as the existence of an "honour culture", rather than relying on an "honour code". It also includes Indigenous voices and perspectives that challenge traditional understandings of intellectual property, as well as new understandings that have arisen as a consequence of Covid-19 and the significant shift to online and remote learning. This book will be of interest to senior university and college administrators who are interested in ensuring the integrity of their institutions. It will also be of interest to those implementing university and college policy, as well as those who support students in their scholarly work.
    Keywords: Academic Integrity in Canada ; Academic Integrity in Higher Education ; Academic Integrity Policy ; Academic Misconduct in Canada ; Academic Misconduct in Higher Education ; Academic Misconduct Policy ; Academic Dishonesty in Canada ; Indigenous Perspectives on Academic Integrity ; Teaching and Learning Ethically ; Assessment and Academic Integrity ; Online and Remote Learning and Academic Integrity ; Covid-19 and Academic Integrity ; Open Access ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy ; bic Book Industry Communication::J Society & social sciences::JN Education::JNK Organization & management of education
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    Springer Nature | Springer
    Publication Date: 2024-03-24
    Description: This open access book addresses communicative aspects of the current COVID-19 pandemic as well as the epidemic of misinformation from the perspective of argumentation theory. Argumentation theory is uniquely placed to understand and account for the challenges of public reason as expressed through argumentative discourse. The book thus focuses on the extent to which the forms, norms and functions of public argumentation have changed in the face of the COVID-19 pandemic. This question is investigated along the three main research lines of the COST Action project CA 17132: European network for Argumentation and Public PoLicY analysis (APPLY): descriptive, normative, and prescriptive. The volume offers a broad range of contributions which treat argumentative phenomena that are directly related to the changes in public discourse in the wake of the outburst of COVID-19. The volume additionally places particular emphasis on expert argumentation, given (i) the importance expert discourse has had over the last two years, and (ii) the challenges that expert argumentation has faced in the public sphere as a result of scientific uncertainty and widespread misinformation. Contributions are divided into three groups, which (i) examine various features and aspects of public and institutional discourse about the COVID-19 pandemic, (ii) scrutinize the way health policies have been discussed, debated, attacked and defended in the public sphere, and (iii) consider a range of proposals meant to improve the quality of public discourse, and public deliberation in particular, in such a way that concrete proposals for argumentative literacy will be brought to light. Overall, this volume constitutes a timely inquiry into all things argumentative in pandemic discourse. This volume is of interest to a broad readership including philosophers, linguists, communication and legal scholars, and members of the wider public who seek to better understand the discourse surrounding communicative phenomena in times of crisis. COST (European Cooperation in Science and Technology) is a funding organisation for research and innovation networks. For more information: www.cost.eu
    Keywords: Argument Propagation ; Fake News Propagation ; Argumentation Covid ; Misinformation Pandemic ; Conspiracy Theory Covid ; Argumentative Literacy ; Public Debate ; Trust/Mistrust in Science ; Public Health Discourse ; Political Interference and Argumentative Styles ; Metalinguistic Arguments on What Counts As “Covid-19 Death” ; Evaluative Component in Pragmatic Argumentation ; public Discourse First Wave Sars-Cov-2 Pandemic in Italy ; Controversies and Dispute in France During the Covid-19 Crisis ; Analysing the Public Debate About Lockdown ; Responding to the COVID Conspiracy Theories ; Why Narratives are More Powerful Arguments than Fact-Checking ; Expanded Understanding of the Role of Analogy ; Argumentative Dark Side of Pandemic Discourse ; Open Access ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFA Philosophy of language ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::J Society and Social Sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCT Media studies
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    Springer Nature | Springer
    Publication Date: 2024-03-24
    Description: This open access book provides a detailed and up-to-date account of the relevant literature on the legibility of different kinds of typefaces, which goes back over 140 years in the case of reading from paper and more than 50 years in the case of reading from screens. It describes the origins of serif and sans serif styles in ancient inscriptions, their adoption in modern printing techniques, and their legibility in different situations and in different populations of readers. It also examines recent research on the legibility of serif and sans serif typefaces when used with internet browsers, smartphones and other hand-held devices. The book investigates the difference in the legibility of serif typefaces and sans serif typefaces when they are used to produce printed material or when they are used to present material on computer monitors or other screens and it explores the differences in readers’ preferences among typefaces. The book’s main focus is on the psychology of reading, but there are clear implications for education and publishing. Indeed, the book can be read with benefit by anyone concerned with communicating with others through written text, whether it is printed on paper or displayed on computer screens.
    Keywords: Legibility of text ; Reading from paper ; Reading from screens ; Sans serif typefaces ; Serif typefaces ; Typography and typographic design ; Open Access ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFC Literacy ; thema EDItEUR::C Language and Linguistics::CB Language: reference and general ; thema EDItEUR::J Society and Social Sciences::JN Education::JNU Teaching of a specific subject
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    Springer Nature | Springer
    Publication Date: 2024-04-05
    Description: This open access book offers a multidisciplinary dialogue on relational anthropology in contemporary economics. A particular view of the human being is often assumed in economic models, but seldom acknowledged let alone explicated. Addressing this neglected area of research in economic studies, altogether the contributors touch upon the importance and potential of virtues, the notions of freedom and self-love, the potential of simulation models, the dialectics of love, and questions of methodology in constructing a relational anthropology for contemporary economics. The overall result is a highly informative and constructive dialogue, establishing inter alia a research agenda for future collaborative and multidisciplinary study.
    Keywords: Reasonable Compromise ; Relational Anthropology for Contemporary Economics ; Towards a Relational Anthropology Fostering ; Economics of Human Flourishing ; God’s Work in the World ; The Deep Compatibility of Real Liberalism ; Homo Amans in the Economy: A Utopia? ; Homo Amans and Revolutionary Altruism ; the Anthropological Foundations of Economic Practice ; How to Change What Cannot be Changed ; Open Access ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies
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    Springer Nature | Springer
    Publication Date: 2024-04-14
    Description: This open access book establishes a dialog among the medical and intelligent system domains for igniting transition toward a sustainable and cost-effective healthcare. The Person-Centered Care (PCC) positions a person in the center of a healthcare system, instead of defining a patient as a set of diagnoses and treatment episodes. The PCC-based conceptual background triggers enhanced application of Artificial Intelligence, as it dissolves the limits of processing traditional medical data records, clinical tests and surveys. Enhanced knowledge for diagnosing, treatment and rehabilitation is captured and utilized by inclusion of data sources characterizing personal lifestyle, and health literacy, and it involves insights derived from smart ambience and wearables data, community networks, and the caregivers’ feedback. The book discusses intelligent systems and their applications for healthcare data analysis, decision making and process design tasks. The measurement systems and efficiency evaluation models analyze ability of intelligent healthcare system to monitor person health and improving quality of life.
    Keywords: Person-centered Healthcare Model ; Heterogeneous Healthcare Data ; Remote Care Feedback Mechanisms ; Monitoring Health Status ; Data-driven Decision Making for Person Health ; Efficiency of Healthcare ; Quality of Person-centered Care ; Big Data for Personal Self-sustainment ; Open Access ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence ; thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering
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  • 54
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    Springer Nature | Springer
    Publication Date: 2022-03-16
    Description: This open access book provides an analysis of contemporary societies and schools shaped by cultural diversity, globalization and migration. This diversity is necessarily reflected in education systems and requires the promotion of intercultural approaches able to improve learning processes and the quality of education. From an international and comparative perspective, this book first presents theoretical and conceptual foundations for seriously considering cultural diversity. The book also compares intercultural approaches and debates generated in countries as diverse as the United States, Canada, Brazil, Switzerland and France. For each national context, the book addresses both the historical roots of intercultural approaches and the concrete initiatives driven by educational policies for their implementation in schools and classrooms. Finally, the book presents discussions surrounding the treatment of linguistic or religious diversity in schools, the emergence of global citizenship education and the key role of teachers in intercultural approaches. This is an open access book.
    Keywords: Multicultural Education ; Intercultural Education ; Diversity in Education ; Ethnic Groups in Education ; Racism and Education ; Ethnocentrism in Education ; Integration and Education ; Assimilation through Education ; Social Justice and Education ; United States and Intercultural Education ; Canada and Intercultural Education ; France and Intercultural Education ; Switzerland and Intercultural Education ; Brazil and Intercultural Education ; Bilingual Education ; Multilingualism and Education ; Religious Diversity ; Global Citizenship Education ; Teacher Education ; Open Access ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy ; bic Book Industry Communication::J Society & social sciences::JN Education
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: A multidisciplinary understanding of the various processes leading to colorectal cancer progression is important for creating promising methods of therapy. Therefore it is necessary to scrutinize the progression of cancer and the therapeutic process through various academic theories. This book examines colorectal cancer - its prevention, pathogenesis, and treatment - through a multidisciplinary lens in an effort to advance understanding of the disease and improve therapeutic efficacy.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Springer Nature | Springer
    Publication Date: 2024-04-08
    Description: This book is open access under a CC BY 4.0 license. This book addresses the age-old problem of infinite regresses in epistemology. How can we ever come to know something if knowing requires having good reasons, and reasons can only be good if they are backed by good reasons in turn? The problem has puzzled philosophers ever since antiquity, giving rise to what is often called Agrippa's Trilemma. The current volume approaches the old problem in a provocative and thoroughly contemporary way. Taking seriously the idea that good reasons are typically probabilistic in character, it develops and defends a new solution that challenges venerable philosophical intuitions and explains why they were mistakenly held. Key to the new solution is the phenomenon of fading foundations, according to which distant reasons are less important than those that are nearby. The phenomenon takes the sting out of Agrippa's Trilemma; moreover, since the theory that describes it is general and abstract, it is readily applicable outside epistemology, notably to debates on infinite regresses in metaphysics. The book is a potential game-changer and a must for any advanced student or researcher in the field.
    Keywords: Epistemology ; Mathematical Logic and Foundations ; Statistical Theory and Methods ; History and Philosophical Foundations of Physics ; Operations Research/Decision Theory ; Philosophical Foundations of Physics and Astronomy ; Operations Research and Decision Theory ; Epistemic Justification ; Infinite Regress ; Regresses in Epistemology ; Regresses in Ethics ; Regresses in Metaphysics ; Regresses in Philosophy of Mind ; Open Access ; Philosophy: epistemology & theory of knowledge ; Mathematical foundations ; Mathematical logic ; Probability & statistics ; History of science ; Operational research ; Management decision making ; bic Book Industry Communication::H Humanities::HP Philosophy::HPK Philosophy: epistemology & theory of knowledge ; bic Book Industry Communication::P Mathematics & science::PB Mathematics::PBC Mathematical foundations ; bic Book Industry Communication::P Mathematics & science::PB Mathematics::PBT Probability & statistics ; bic Book Industry Communication::P Mathematics & science::PD Science: general issues::PDX History of science ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJT Operational research ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTK Philosophy: epistemology and theory of knowledge ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBC Mathematical foundations ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBT Probability and statistics ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDX History of science ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJT Operational research
    Language: English
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: This open access book provides anthropological insights into the arduous yet rewarding journeys involved in selected TESOL teachers’ pedagogical transition to teaching English for Academic Purposes (EAP) at universities in Shanghai, the largest metropolitan area in China. Applying a unique combination of ethnography and phenomenology, the book offers innovative new perspectives on teacher education research. Drawing on the latest language education theory, it outlines a practitioner-friendly approach to EAP literacy. Teacher readers will especially benefit from the case studies presented here, which provide role models for teacher change in educational reform, as well as advice on their academic careers. In addition to addressing a timely and important research gap on EAP teachers in non-Western countries, the book is the ideal choice for readers interested in an update on English education in China.
    Keywords: Philosophy of Education ; Language Education ; Teaching and Teacher Education ; Social Anthropology ; EAP Teacher Education ; EAP Teaching ; University English Teaching ; China Higher Education ; Teacher Change ; Open Access ; Philosophy & theory of education ; Language: reference & general ; Teacher training ; Social & cultural anthropology ; bic Book Industry Communication::J Society & social sciences::JN Education::JNA Philosophy & theory of education ; bic Book Industry Communication::C Language::CB Language: reference & general ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education::JNMT Teacher training ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHM Anthropology::JHMC Social & cultural anthropology, ethnography
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: “Gynaecological Malignancies - Updates and Advances” aims to present a review of the significant advances in the understanding and management of gynaecological malignancies. Major areas of importance in this field will be covered, incorporating new knowledge that has arisen due to the advancements in molecular techniques and the ability to correlate these molecular changes with clinical behaviour of gynaecologic tumours. The therapeutic implications of molecular subtyping to match appropriate therapies and the appreciation of the use of up to date radiotherapy techniques will be explored.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book provides an excellent overview of how melanoma is treated in the clinic. Since oncologists and clinicians across the globe contributed to this book, each area also explores the unique burdens that geographical areas experience from melanoma subtypes and how these are treated in different settings. It also includes several chapters that illustrate novel methods for diagnosing melanoma in the clinic using new technologies, which are likely to significantly improve outcomes. Several chapters cover surgical techniques and other present very rare or challenging clinical cases of melanoma and how these were treated. The book is geared towards informing clinicians and even patients how melanoma arises, what tools are available and which decisions need to be made by patients and their families in order to treat this devastating disease.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: This open access book is based on selected presentations from Topic Study Group 21: Mathematical Applications and Modelling in the Teaching and Learning of Mathematics at the 13th International Congress on Mathematical Education (ICME 13), held in Hamburg, Germany on July 24–31, 2016. It contributes to the theory, research and teaching practice concerning this key topic by taking into account the importance of relations between mathematics and the real world. Further, the book addresses the “balancing act” between developing students’ modelling skills on the one hand, and using modelling to help them learn mathematics on the other, which arises from the integration of modelling into classrooms. The contributions, prepared by authors from 9 countries, reflect the spectrum of international debates on the topic, and the examples presented span schooling from years 1 to 12, teacher education, and teaching modelling at the tertiary level. In addition the book highlights professional learning and development for in-service teachers, particularly in systems where the introduction of modelling into curricula means reassessing how mathematics is taught. Given its scope, the book will appeal to researchers and teacher educators in mathematics education, as well as pre-service teachers and school and university educators
    Keywords: Mathematics Education ; Learning & Instruction ; Teaching and Teacher Education ; Education ; Pedagogical issues of integration into classroom practice ; assessment of modelling competencies ; teachers as learners of mathematical modelling ; technological influences on modelling education ; managing group interactions in modelling ; mathematical model ; modelling problems ; heuristic strategies ; teaching mathematical modelling ; modelling competencies ; learning mathematics modelling ; interpretations modelling ; pedagogical practice and research ; modelling perspective ; teaching practices in mathematical modelling ; Open Access ; Teaching of a specific subject ; Mathematics ; Teaching skills & techniques ; Cognition & cognitive psychology ; Teacher training ; bic Book Industry Communication::J Society & social sciences::JN Education::JNU Teaching of a specific subject ; bic Book Industry Communication::J Society & social sciences::JN Education::JNT Teaching skills & techniques ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education::JNMT Teacher training
    Language: English
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: This open access volume provides insight into how organizations change through the adoption of digital technologies. Opportunities and challenges for individuals as well as the organization are addressed. It features four major themes: 1. Current research exploring the theoretical underpinnings of digital transformation of organizations. 2. Insights into available digital technologies as well as organizational requirements for technology adoption. 3. Issues and challenges for designing and implementing digital transformation in learning organizations. 4. Case studies, empirical research findings, and examples from organizations which successfully adopted digital workplace learning.
    Keywords: Administration, Organization and Leadership ; Computers and Education ; Educational Technology ; Organization and Leadership ; Education ; Open Access ; Digital technologies for education ; Digital transformation ; Digital organizational learning and education ; Digital tools for change management ; Transformational learnins ; Transformation of educational organizations ; Educational administration & organization ; Educational equipment & technology, computer-aided learning (CAL) ; bic Book Industry Communication::J Society & social sciences::JN Education::JNK Organization & management of education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNV Educational equipment & technology, computer-aided learning (CAL)
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-04-01
    Description: ​This open access book describes modern applications of computational human modeling in an effort to advance neurology, cancer treatment, and radio-frequency studies including regulatory, safety, and wireless communication fields. Readers working on any application that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest models and techniques available to assess a given technology’s safety and efficacy in a timely and efficient manner. Describes computational human body phantom construction and application; Explains new practices in computational human body modeling for electromagnetic safety and exposure evaluations; Includes a survey of modern applications for which computational human phantoms are critical.
    Keywords: Biomedical Engineering and Bioengineering ; Biomedical Engineering/Biotechnology ; Circuits and Systems ; Biotechnology ; Electronic Circuits and Systems ; Electromagnetic Modeling for Electrical and Biological Systems ; Anatomical Models for Radiation Dosimetry ; Computational Human Phantoms ; Computational Human Models ; Electromagnetic safety and exposure evaluations ; Open Access ; Biomedical engineering ; Electronics: circuits & components ; thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFC Electronics: circuits and components
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    Springer Nature | Springer
    Publication Date: 2024-03-29
    Description: This open access book shows the breadth and various facets of e-Science, while also illustrating their shared core. Changes in scientific work are driven by the shift to grid-based worlds, the use of information and communication systems, and the existential infrastructure, which includes global collaboration. In this context, the book addresses emerging issues such as open access, collaboration and virtual communities and highlights the diverse range of developments associated with e-Science. As such, it will be of interest to researchers and scholars in the fields of information technology and knowledge management.
    Keywords: Science and Technology Studies ; Media and Communication ; Business Information Systems ; Computer Applications ; Education, general ; Knowledge Management ; Science Communication ; Computer and Information Systems Applications ; Digital Education and Educational Technology ; Open Access ; Grid computing ; Science 2.0 ; Research network ; Education portal ; Virtual organization ; Governance ; Social control ; Science collaboration ; Digitization ; Digital research infrastructures ; Cyberinfrastructure software ; Sustainability ; Software sustainability ; Sociology ; Media studies ; Business mathematics & systems ; Information technology: general issues ; Education ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCT Media studies ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJQ Business mathematics and systems ; thema EDItEUR::U Computing and Information Technology::UB Information technology: general topics ; thema EDItEUR::J Society and Social Sciences::JN Education ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMK Knowledge management
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-04-05
    Description: This open access book provides an extensive review of ethical and regulatory issues related to human infection challenge studies, with a particular focus on the expansion of this type of research into endemic settings and/or low- and middle-income countries (LMICs). Human challenge studies (HCS) involve the intentional infection of research participants, and this type of research is rapidly increasing in frequency worldwide. HCS are widely considered to be an especially promising approach to vaccine development, including for pathogens endemic to LMICs. However, challenge studies are sometimes controversial and raise complex ethical issues, some of which are especially salient in endemic and/or LMIC settings. Informed by qualitative interviews with experts in infectious diseases and bioethics, this book highlights areas of ethical consensus and controversy concerning this kind of research. As the first volume to focus on ethical issues associated with human challenge studies, it sets the agenda for further work in this important area of global health research; contributes to current debates in research ethics; and aims to inform regulatory policy and research practice. Insofar as it focuses on HCS in (endemic) settings where diseases are present and/or widespread, much of the analysis provided here is directly relevant to HCS involving pandemic diseases including COVID19.
    Keywords: Bioethics ; Infectious Diseases ; Vaccine ; Development and Health ; Moral Philosophy and Applied Ethics ; Internal Medicine ; Pharmacology ; Development Studies ; human challenge studies ; Open Access ; capacity building in low-income countries ; capacity building in middle-income countries ; malariotherapy ; intentional infection ; ethics of challenge studies ; challenge studies in endemic settings ; challenge studies and vulnerable populations ; Falciparum malaria challenge studies in Africa ; Infectious & contagious diseases ; Immunology ; Development studies ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAD Bioethics ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTP Development studies
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-04-01
    Description: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
    Keywords: Imaging / Radiology ; Neurology ; Neurosurgery ; Radiology ; Health Sciences ; Open Access ; Neuro ; IDKD ; Diagnostic Imaging ; Medical imaging ; Neurology & clinical neurophysiology ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKS Medical imaging::MKSH Medical imaging: radiology ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology ; thema EDItEUR::M Medicine and Nursing::MN Surgery::MNN Neurosurgery
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    Springer Nature | Springer
    Publication Date: 2024-04-11
    Description: This open access book explores supply chains strategies to help companies face challenges such as societal emergency, digitalization, climate changes and scarcity of resources. The book identifies industrial scenarios for the next decade based on the analysis of trends at social, economic, environmental technological and political level, and examines how they may impact on supply chain processes and how to design next generation supply chains to answer these challenges. By mapping enabling technologies for supply chain innovation, the book proposes a roadmap for the full implementation of the supply chain strategies based on the integration of production and logistics processes. Case studies from process industry, discrete manufacturing, distribution and logistics, as well as ICT providers are provided, and policy recommendations are put forward to support companies in this transformative process.
    Keywords: Engineering Economics, Organization, Logistics, Marketing ; R & D/Technology Policy ; Supply Chain Management ; Industrial Management ; Economics ; Operations Management ; Open Access ; Logistics ; Discrete Manufacturing ; Supply Chain Models ; human-centered supply chain ; customer-driven supply chain ; Engineering: general ; Management of specific areas ; Research & development management ; Purchasing & supply management ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBC Engineering: general ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMV Management of specific areas::KJMV6 Research and development management ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMV Management of specific areas::KJMV8 Purchasing and supply management
    Language: English
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: Das Open-Access-Buch untersucht am Beispiel des Europäischen Gerichtshofs für Menschenrechte (EGMR) und des Interamerikanischen Menschenrechtsgerichtshofs (IAGMR), welche Rolle innerstaatliche Gerichte bei der Umsetzung internationaler Entscheidungen wahrnehmen. Wann sind sie bereit ihre Pendants in Straßburg bzw. San José bei der Umsetzung ihrer Entscheidungen zu unterstützen und diese gleichsam unmittelbar „anzuwenden“, und wo ziehen sie Grenzen und rote Linien? Was sind die Probleme, die ihnen begegnen, und befinden sich Gerichte tatsächlich im Wandel hin zu einer defensiveren und weniger völkerrechtsfreundlichen Haltung, wie einige jüngere Beispiele vermuten lassen? Das Werk widmet sich der Frage, welche Wirkungen innerstaatliche Gerichte bereit sind, den Entscheidungen der Menschenrechtsgerichte zukommen zu lassen – und zwar genau dann, wenn sich das innerstaatliche Recht nicht dazu äußert. Es zeigt auf, dass hinter der vermeintlich technischen Ausgangsfrage fundamentale Fragen verfassungsrechtlicher Natur stehen und sich am Beispiel der Menschenrechtsgerichte einige der zentralen Schwierigkeiten und Probleme zeigen, wie sie beim Zusammenspiel von Rechtsordnungen in Zeiten globalen Regierens entstehen.
    Keywords: Human Rights ; European Fundamental Rights and Freedoms ; EGMR ; IAGMR ; Unmittelbare Anwendbarkeit von Völkervertragsrecht ; Regionale Menschenrechtssysteme ; Inter-partes-Bindungswirkung ; Open Access ; Human rights, civil rights ; Public international law: human rights ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPV Political control & freedoms::JPVH Human rights ; bic Book Industry Communication::L Law::LB International law::LBB Public international law::LBBR International human rights law
    Language: German
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    Springer Nature | Springer
    Publication Date: 2024-04-14
    Description: This open access book proposes a novel approach to Artificial Intelligence (AI) ethics. AI offers many advantages: better and faster medical diagnoses, improved business processes and efficiency, and the automation of boring work. But undesirable and ethically problematic consequences are possible too: biases and discrimination, breaches of privacy and security, and societal distortions such as unemployment, economic exploitation and weakened democratic processes. There is even a prospect, ultimately, of super-intelligent machines replacing humans. The key question, then, is: how can we benefit from AI while addressing its ethical problems? This book presents an innovative answer to the question by presenting a different perspective on AI and its ethical consequences. Instead of looking at individual AI techniques, applications or ethical issues, we can understand AI as a system of ecosystems, consisting of numerous interdependent technologies, applications and stakeholders. Developing this idea, the book explores how AI ecosystems can be shaped to foster human flourishing. Drawing on rich empirical insights and detailed conceptual analysis, it suggests practical measures to ensure that AI is used to make the world a better place.
    Keywords: Artificial Intelligence ; Ethics ; Computers and Society ; Philosophy of Technology ; Business Ethics ; Applied Ethics ; Ethics of Technology ; Computer Ethics ; Information Ethics ; Responsible Research and Innovation ; Innovation Ecosystem ; Engineering Ethics ; Corporate Social Responsibility ; Open Access ; Ethics & moral philosophy ; Ethical & social aspects of IT ; Philosophy ; Business ethics & social responsibility ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTQ Ethics and moral philosophy ; thema EDItEUR::U Computing and Information Technology::UB Information technology: general topics::UBJ Digital and information technologies: social and ethical aspects ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJG Business ethics and social responsibility
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Hematology encompasses the physiology and pathology of blood and of the blood-forming organs. In common with other areas of medicine, the pace of change in hematology has been breathtaking over recent years. There are now many treatment options available to the modern hematologist and, happily, a greatly improved outlook for the vast majority of patients with blood disorders and malignancies. Improvements in the clinic reflect, and in many respects are driven by, advances in our scientific understanding of hematological processes under both normal and disease conditions. Hematology - Science and Practice consists of a selection of essays which aim to inform both specialist and non-specialist readers about some of the latest advances in hematology, in both laboratory and clinic.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-04-11
    Description: This open access book introduces design for Sustainable Product-Service Systems (S.PSS) and for Sustainable Distributed Economies (S.DE). These are introduced as technical and operative tools for the development of a new generation of designers, responsible and capable of designing environmentally, socially and economically sustainable solutions, accessible to all. The book provides a comprehensive framework and also practical tools to support the system design for sustainability process. It overviews methodologies, tools and strategies for Sustainable PSS design applied to Distributed Economies (DE) and provides strategies and design guidelines. All of these are highlighted and expanded upon with international case studies.
    Keywords: Engineering Design ; Sustainability Management ; Development and Sustainability ; Industrial and Production Engineering ; Management ; Development Studies ; Design for Sustainability ; Product-Service System (PSS) ; Sustainable Development ; Distributed Economies (DE) ; Circular Economy ; Social Equity and Cohesion ; Open Access ; Technical design ; Business & the environment ; ‘green’ approaches to business ; Sustainability ; Production engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBD Technical design ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJJ Business and the environment; ‘green’ approaches to business ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RNU Sustainability ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGP Production and industrial engineering
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Colorectal cancer is a common disease, affecting millions worldwide and represents a global health problem. Effective therapeutic solutions and control measures for the disease will come from the collective research efforts of clinicians and scientists worldwide. This book presents the current status of the strides being made to understand the fundamental scientific basis of colorectal cancer. It provides contributions from scientists, clinicians and investigators from 20 different countries. The four sections of this volume examine the evidence and data in relation to genes and various polymorphisms, tumor microenvironment and infections associated with colorectal cancer. An increasingly better appreciation of the complex inter-connected basic biology of colorectal cancer will translate into effective measures for management and treatment of the disease. Research scientists and investigators as well as clinicians searching for a good understanding of the disease will find this book useful.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-04-11
    Description: This book is open access under a CC BY 4.0 license. It presents the results of the ComBoNDT European project, which aimed at the development of more secure, time- and cost-saving extended non-destructive inspection tools for carbon fiber reinforced plastics, adhered surfaces and bonded joints. The book reports the optimal use of composite materials to allow weight savings, reduction in fuel consumptions, savings during production and higher cost efficiency for ground operations.
    Keywords: Structural Materials ; Aerospace Technology and Astronautics ; Manufacturing, Machines, Tools, Processes ; Characterization and Evaluation of Materials ; Surfaces and Interfaces, Thin Films ; Ceramics, Glass, Composites, Natural Materials ; Machines, Tools, Processes ; Characterization and Analytical Technique ; Surfaces, Interfaces and Thin Film ; Ceramics ; NDT composites ; NDT aircraft ; CFRP NDT testing ; innovative lightweight materials ; aircraft lifecycle ; adhesive bonding ; adhesively bonded joints ; surface cleaning ; ComBoNDT ; Open Access ; Materials science ; Structural engineering ; Aerospace & aviation technology ; Astronautics ; Production engineering ; Testing of materials ; Surface chemistry & adsorption ; Industrial chemistry & chemical engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TR Transport technology and trades::TRP Aerospace and aviation technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGP Production and industrial engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science::TGMT Testing of materials ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering::TDCQ Ceramic and glass technology
    Language: English
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: This open access book contributes to the creation of a cyber ecosystem supported by blockchain technology in which technology and people can coexist in harmony. Blockchains have shown that trusted records, or ledgers, of permanent data can be stored on the Internet in a decentralized manner. The decentralization of the recording process is expected to significantly economize the cost of transactions. Creating a ledger on data, a blockchain makes it possible to designate the owner of each piece of data, to trade data pieces, and to market them. This book examines the formation of markets for various types of data from the theory of market quality proposed and developed by M. Yano. Blockchains are expected to give data itself the status of a new production factor. Bringing ownership of data to the hands of data producers, blockchains can reduce the possibility of information leakage, enhance the sharing and use of IoT data, and prevent data monopoly and misuse. The industry will have a bright future as soon as better technology is developed and when a healthy infrastructure is created to support the blockchain market.
    Keywords: IT in Business ; Economic Theory/Quantitative Economics/Mathematical Methods ; Computer Appl. in Social and Behavioral Sciences ; Computational Social Sciences ; Social Policy ; Open Access ; Blockchain ; cyber ecosystem ; decentralized ledger ; Crypt Data ; IoT ; Cryptocurrency ; Business mathematics & systems ; Business applications ; Economic theory & philosophy ; Computer applications in the social & behavioural sciences ; Political economy ; Social & ethical issues ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJQ Business mathematics & systems ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCA Economic theory & philosophy ; bic Book Industry Communication::J Society & social sciences ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCP Political economy
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: This open access handbook brings together the latest research from a wide range of internationally influential scholars to analyze educational policy research from international, historical and interdisciplinary perspectives. By effectively breaking through the boundaries between countries and disciplines, it presents new theories, techniques and methods for contemporary education policy, and illustrates the educational policies and educational reform practices that various countries have introduced to meet the challenges of continuous change. This volume focuses on policies and changes in schools and classrooms. The studies on school changes present the differences in the policies and challenges of K-12 schools and universities in different countries and regions, and in connection with the contradictions and conflicts between tradition and modernization, as well as the changing roles of various stakeholders, especially that of teachers. In terms of curriculum and instruction, many countries have undertaken experiments and introduced changes based on two major themes: “what to teach” and “how to teach”. International education assessments represented by PISA not only promote the improvement and extensive application of educational assessment and testing techniques, but have also had far-reaching impacts on education policies and education reforms in many countries. Focusing on the changes in educational policies at the micro level, this volume comprehensively reveals the complex interactions between school organizations, teachers, curricula, teaching and learning, evaluation and other elements within the education system, as well as the latest related reforms worldwide. ; Brings together in a single volume a collection of international scholars from multiple disciplines Pushes the boundaries of education policy studies through its insightful analyses Equips readers to handle the complexities of policy research by employing critical thinking
    Keywords: Educational Policy and Politics ; International and Comparative Education ; International assessments ; Globalization and educational reform ; International cooperation ; International "agents" in modernizing ; Educational change ; The politics of education ; International/ transnational studies ; Historical studies ; Cultural diversity ; Regional differences ; Open Access ; Educational strategies & policy ; Education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy ; bic Book Industry Communication::J Society & social sciences::JN Education
    Language: English
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: This open access book explores the transformative experiences of participants in the University of Sydney’s National Centre for Cultural Competence (NCCC) programs. The establishment of the NCCC was viewed as a critical point of departure for developing an institution-wide agenda of cultural competence. The NCCC’s work since its inception reflects efforts to lay important foundations for cultural change at the University. With the ultimate aim of establishing cultural competence as an agent for transformational change and social justice education, the NCCC has steadily expanded its research and teaching work both within and beyond the University of Sydney. Further, it has developed foundational resources to support and encourage University staff to integrate cultural competence philosophy and pedagogy in their curricula, teaching and research. This includes the ability to engage meaningfully with the cultures, histories and contemporary issues in Aboriginal and Torres Strait Islander communities. The NCCC programs have been designed to encourage participants to learn about who they are and how they can positively impact the transformational change the University has begun. The book presents participants’ reflections on their experiences at the organisational and personal level. Readers will gain insights into a range of topics including cultural competence, communities of practice, policy implementation, and transformative leadership at the interface between higher education and professional lives.
    Keywords: Higher Education ; Sociology of Education ; Educational Policy and Politics ; Education Policy ; Cultural competence in the higher education sector ; Transformative leadership in professional development programs ; Intercultural capabilities for academic and professional staff ; cultural competence for academic and professional staff ; Cultural competence embedded in professional lives ; transformative nature of professional development programs ; building communities of practice ; policy implementation in the higher education sector ; critical reflection and transformative leadership ; learning cultural competence ; best practices for professional development programs ; culturally competent organisational wide ; Open Access ; Higher & further education, tertiary education ; Education ; Social research & statistics ; Educational strategies & policy ; Central / national / federal government policies ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education ; bic Book Industry Communication::J Society & social sciences::JN Education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPQ Central government::JPQB Central government policies
    Language: English
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: This Open Access book is about the development of a common understanding of environmental citizenship. It conceptualizes and frames environmental citizenship taking an educational perspective. Organized in four complementary parts, the book first explains the political, economic and societal dimensions of the concept. Next, it examines environmental citizenship as a psychological concept with a specific focus on knowledge, values, beliefs and attitudes. It then explores environmental citizenship within the context of environmental education and education for sustainability. It elaborates responsible environmental behaviour, youth activism and education for sustainability through the lens of environmental citizenship. Finally, it discusses the concept within the context of different educational levels, such as primary and secondary education in formal and non-formal settings. Environmental citizenship is a key factor in sustainability, green and cycle economy, and low-carbon society, and an important aspect in addressing global environmental problems. It has been an influential concept in many different arenas such as economy, policy, philosophy, and organizational marketing. In the field of education, the concept could be better exploited and established, however. Education and, especially, environmental discourses in science education have a great deal to contribute to the adoption and promotion of environmental citizenship.
    Keywords: Science Education ; Sustainable Development ; Social Justice, Equality and Human Rights ; Environmental and Sustainability Education ; Environmental Social Sciences ; Human Rights ; Sustainability / sustainable development ; Environmental citizenship ; Environmental citizen ; Environmental education ; Education for environmental citizenship ; Education for sustainability ; ENEC ; EU Horizon 2020 ; EU-roadmap 2050 ; European Network for Environmental Citizenship ; Environmental Behavior ; Environmental citizenship from educational perspective ; Open Access ; Teaching of a specific subject ; Science: general issues ; Sustainability ; Politics & government ; Education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNU Teaching of a specific subject ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNU Sustainability ; bic Book Industry Communication::J Society & social sciences::JP Politics & government ; bic Book Industry Communication::J Society & social sciences::JN Education
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    Springer Nature | Springer
    Publication Date: 2024-03-29
    Description: This Open Access book presents an international group of scholars seeking to understand how youth from different cultures relate to modern multidimensional concepts of citizenship, and the roles that education and society have in shaping the views of the world’s future citizens. The book also explores how different aspects of citizenship, such as attitudes towards diverse population groups and concerns for social issues, relate to classical definitions of norm-based citizenship from the political sciences. Authors from Asia, Europe, and Latin America provide a series of in-depth investigations into how concepts of “good citizenship” are shaped in different regions of the globe, using the rich comparative data from the IEA’s International Civic and Citizenship Study (ICCS) 2016. In twelve chapters, the authors review the concept of “good citizenship”; how citizenship norms adherence is configured into profiles across countries; and what country, school, and background factors are related to how students adhere to citizenship norms. Recognizing contingent social and political situations in specific regions of the world, the present books offer six chapters where authors apply their expertise to offer locally relevant and pertinent observations on how young people from diverse cultures understand and relate to different dimensions of citizenship in countries of Asia, Europe, and Latin America. The present book is of relevance for different audiences interested in civic education and political socialization, including social sciences and education, integrating topics from political science, sociology, political psychology, and law.
    Keywords: IEA ; Large-scale studies in education ; Open Access ; Civic education ; School effectiveness ; International Civics and Citizenship Study ; ICCS ; Large-scale assessment ; ICCS data in civic education ; Comparative research in civic education ; Latin American political culture and citizenship norms ; Corruption among students in Latin America ; Citizenship norms among native and immigrant students ; Asian adolescents’ understanding of democracy ; Asian dtudents and civic engagement ; bic Book Industry Communication::J Society & social sciences::JN Education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNK Organization & management of education::JNKD Examinations & assessment ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPV Political control & freedoms::JPVH Human rights::JPVH1 Civil rights & citizenship ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy ; thema EDItEUR::J Society and Social Sciences::JN Education ; thema EDItEUR::J Society and Social Sciences::JN Education::JND Educational systems and structures::JNDH Education: examinations and assessment ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPV Political control and freedoms::JPVC Civics and citizenship ; thema EDItEUR::J Society and Social Sciences::JN Education::JNF Educational strategies and policy
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  • 78
    Publication Date: 2024-04-04
    Description: This open access volume is based on the 'Early Carnap in Context’ workshop that took place in Konstanz in 2017 and looks at Rudolf Carnap’s philosophy, documented in his recently released diaries, from a combination of historical, cultural and philosophical perspectives. It enables further evaluation of the diaries and traces newly found interrelationships and their systematic definition. From a cultural and historical point of view, Logical Empiricism and Carnap’s pivotal opus, The Logical Structure of the World, did not evolve in a vacuum. This applies equally in a history of philosophy context as well as under consideration of contemporary historical and cultural influences such as the socio-cultural setting in Vienna and Prague, the correlation between Logical Empiricism and Bauhaus modernism, the connection to the Life Reform Movement or the Youth Movement with its own life philosophy. Pursuing Carnap’s progression on a micro level of history and referring the results back to Carnap’s philosophy is now facilitated by recent access to his Diaries from 1908–1935. These shorthand records, reading lists, travel reports and notes constitute a valuable source for the research of networks and social movements which left their mark on him.
    Keywords: Philosophy of Science ; European History ; Rudolf Carnap ; Carnap’s Diaries ; The Logical Structure of the World ; Life Reform Movement ; Vienna Circle ; Open Access ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDA Philosophy of science ; thema EDItEUR::N History and Archaeology::NH History::NHD European history
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-04-14
    Description: This open access book covers the use of data science, including advanced machine learning, big data analytics, Semantic Web technologies, natural language processing, social media analysis, time series analysis, among others, for applications in economics and finance. In addition, it shows some successful applications of advanced data science solutions used to extract new knowledge from data in order to improve economic forecasting models. The book starts with an introduction on the use of data science technologies in economics and finance and is followed by thirteen chapters showing success stories of the application of specific data science methodologies, touching on particular topics related to novel big data sources and technologies for economic analysis (e.g. social media and news); big data models leveraging on supervised/unsupervised (deep) machine learning; natural language processing to build economic and financial indicators; and forecasting and nowcasting of economic variables through time series analysis. This book is relevant to all stakeholders involved in digital and data-intensive research in economics and finance, helping them to understand the main opportunities and challenges, become familiar with the latest methodological findings, and learn how to use and evaluate the performances of novel tools and frameworks. It primarily targets data scientists and business analysts exploiting data science technologies, and it will also be a useful resource to research students in disciplines and courses related to these topics. Overall, readers will learn modern and effective data science solutions to create tangible innovations for economic and financial applications.
    Keywords: Data Mining and Knowledge Discovery ; Machine Learning ; Business Information Systems ; Big Data/Analytics ; Computer Appl. in Administrative Data Processing ; Information Storage and Retrieval ; IT in Business ; Computer and Information Systems Applications ; Open Access ; Data Mining ; Big Data ; Data Analytics ; Decision Support Systems ; Semantics and Reasoning ; Expert systems / knowledge-based systems ; Business mathematics & systems ; Public administration ; Information technology: general issues ; Information retrieval ; Data warehousing ; thema EDItEUR::U Computing and Information Technology::UN Databases::UNF Data mining ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence::UYQM Machine learning ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJQ Business mathematics and systems ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPP Public administration ; thema EDItEUR::U Computing and Information Technology::UN Databases::UNH Information retrieval
    Language: English
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  • 80
    Publication Date: 2021-02-10
    Description: This open access book presents up-to-date analyses of community-based approaches to sustainable resource management of SEPLS (socio-ecological production landscapes and seascapes) in areas where a harmonious relationship between the natural environment and the people who inhabit it is essential to ensure community and environmental well-being as well as to build resilience in the ecosystems that support this well-being. Understanding SEPLS and the forces of change that can weaken their resilience requires the integration of knowledge across a wide range of academic disciplines as well as from indigenous knowledge and experience. Moreover, given the wide variation in the socio-ecological makeup of SEPLS around the globe, as well as in their political and economic contexts, individual communities will be at the forefront of developing the measures appropriate for their unique circumstances. This in turn requires robust communication systems and broad participatory approaches. Sustainability science (SuS) research is highly integrated, participatory and solutions driven, and as such is well suited to the study of SEPLS. Through case studies, literature reviews and SuS analyses, the book explores various approaches to stakeholder participation, policy development and appropriate action for the future of SEPLS. It provides communities, researchers and decision-makers at various levels with new tools and strategies for exploring scenarios and creating future visions for sustainable societies.
    Keywords: Environmental Management ; Landscape Ecology ; Development and Sustainability ; Landscape/Regional and Urban Planning ; Environmental Sociology ; Sustainable Development ; Development Studies ; Geography ; Biotechnology ; Environmental Social Sciences ; Indigenous and local knowledge ; Science-policy interface ; Ecosystem services ; Future scenarios ; Stakeholder analysis ; Visualization ; Satoyama ; Satoumi ; SEPLS ; Social-ecological system ; Open Access ; Environmental management, ; Botany & plant sciences ; Sustainability ; Regional & area planning ; Sociology ; The environment ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNF Environmental management ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PST Botany & plant sciences::PSTS Plant ecology ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNU Sustainability ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RP Regional & area planning ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHB Sociology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: During the last decades, numerous studies about stem cells and regenerative medicine highlighted new therapeutic approaches to treat several neurological disorders. It is noteworthy that the current optimism over potential stem cell therapies is driven by new understandings of stem cell biology leading to specific cell fate decision. The objectives of this book were: 1) to offer a general understanding of signaling pathways underlying the capacity of differentiation of several types of stem cells into neurons, during the development; 2) to understand how those pathways are altered in pathological conditions; 3) to describe advances in cellular therapy that could be use to restore central nervous system dysfunction in pathological conditions.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: In spite of advances in the cancer research field, cancer treatment still challenges researchers and clinicians, as proven by the still impressive and increasing number of worldwide cancer-related deaths. Updates on Cancer Treatment is an attempt to integrate into a book volume various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book offers significant coverage on different aspects of cancer from risk factors to the mechanisms leading to tumor progression and metastasis. Although tremendous progress has been made in cancer research and treatment, cancer metastasis remains a major unmet clinical need. The life and death of many cancer patients hangs on the degree of metastasis. This book provides new perspectives for diagnosis and cancer therapy. It includes new technologies and a new basis for current cancer therapies. To guarantee the high quality of this book, important topics are included and rigorously discussed in a simple and authentic way. The book addresses important challenges governing tumor progression and metastasis and brings new responses to both diagnosis and therapy. This book is a great source of knowledge and will be useful for researchers, medical doctors, oncologists, graduate and medical students, continued medical educators, health care providers, and all individuals interested in understanding cancer and its challenges.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-04-14
    Description: This Open Access book presents the results of the "Collaborative Embedded Systems" (CrESt) project, aimed at adapting and complementing the methodology underlying modeling techniques developed to cope with the challenges of the dynamic structures of collaborative embedded systems (CESs) based on the SPES development methodology. In order to manage the high complexity of the individual systems and the dynamically formed interaction structures at runtime, advanced and powerful development methods are required that extend the current state of the art in the development of embedded systems and cyber-physical systems. The methodological contributions of the project support the effective and efficient development of CESs in dynamic and uncertain contexts, with special emphasis on the reliability and variability of individual systems and the creation of networks of such systems at runtime. The project was funded by the German Federal Ministry of Education and Research (BMBF), and the case studies are therefore selected from areas that are highly relevant for Germany’s economy (automotive, industrial production, power generation, and robotics). It also supports the digitalization of complex and transformable industrial plants in the context of the German government's "Industry 4.0" initiative, and the project results provide a solid foundation for implementing the German government's high-tech strategy "Innovations for Germany" in the coming years.
    Keywords: Software Engineering ; Software Management ; Automotive Engineering ; Special Purpose and Application-Based Systems ; IT in Business ; Model-Driven Software Development ; Requirements Engineering ; Automotive Software Engineering ; Embedded Systems ; Open Access ; SPES Methodology ; Simulation ; Co-Design of Systems ; Business mathematics & systems ; Business applications ; Automotive technology & trades ; Automotive (motor mechanic) skills ; Expert systems / knowledge-based systems ; thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering::UMZ Software Engineering ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJQ Business mathematics and systems ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TR Transport technology and trades::TRC Automotive technology and trades ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence::UYQE Expert systems / knowledge-based systems
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Acute lymphoblastic leukemia (ALL) has turned from a universally fatal to a highly curable disease in little more than four decades. Even though differences in outcome continue to exist between children and adults, intense efforts are under way to overcome this discrepancy and improve the prognosis of adult patients as well. This exemplary progress in ALL therapy has been possible by the combination of an increasingly better understanding of the biology of the disease, availability of a range of effective drugs, and astute designs and relentless executions of many clinical trials. ALL is a complex disease requiring complex therapy. Whereas this book cannot provide a comprehensive review of every one of its many facets, the chapters from many investigators from around the world nevertheless cover a number of relevant topics: aspects of the epidemiology of ALL in Hispanics, ophthalmologic manifestations of ALL, overviews of current therapy and drug-resistance mechanisms, novel biological pathways and targets, new drugs in development, and long-term consequences of CNS prophylaxis and therapy. The publishers and editor therefore hope that the prospective readers will find enough insight and information for their own endeavors.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Soft tissue tumors include a heterogeneous group of diagnostic entities, most of them benign in nature and behavior. Malignant entities, soft tissue sarcomas, are rare tumors that account for1% of all malignancies. These are predominantly tumors of adults, but 15% arise in children and adolescents. The wide biological diversity of soft tissue tumors, combined with their high incidence and potential morbidity and mortality represent challenges to contemporary researches, both at the level of basic and clinical science. Determining whether a soft tissue mass is benign or malignant is vital for appropriate management. This book is the result of collaboration between several authors, experts in their fields; they succeeded in translating the complexity of soft tissue tumors and the diversity in the diagnosis and management of these tumors.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Cancer is the leading cause of death in economically developed countries and the second leading cause of death in developing countries. It is an enormous global health encumbrance, growing at an alarming pace. Global statistics show that in 2030 alone, about 21.4 million new cancer cases and 13.2 million cancer deaths are expected to occur, simply due to the growth, aging of the population, adoption of new lifestyles and behaviors. Amongst the several modes of treatment for cancer available, Radiation treatment has a major impact due to technological advancement in recent times. This book discusses the pros and cons of this treatment modality. This book "Modern Practices in Radiation Therapy" has collaged topics contributed by top notch professionals and researchers all around the world.
    Keywords: Radiotherapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 88
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    Springer Nature | Springer
    Publication Date: 2024-04-14
    Description: This open access book details the relationship between the artist and their created works, using tools such as information technology, computer environments, and interactive devices, for a range of information sources and application domains. This has produced new kinds of created works which can be viewed, explored, and interacted with, either as an installation or via a virtual environment such as the Internet. These processes generate new dimensions of understanding and experience for both the artist and the public’s relationships with the works that are produced. This has raised a variety of interdisciplinary opportunities and issues, and these are examined. The symbiotic relationship between artistic works and the cultural context in which they are produced is reviewed. Technology can provide continuity by making traditional methods and techniques more efficient and effective. It can also provide discontinuity by opening up new perspectives and paradigms. This can generate new ideas, and produce a greater understanding of artistic processes and how they are implemented in practice. Tools have been used from the earliest times to create and modify artistic works. For example, naturally occurring pigments have been used for cave paintings. What has been created provides insight into the cultural context and social environment at the time of creation. There is an interplay between the goal of the creator, the selection and use of appropriate tools, and the materials and representations chosen. Technology, Design and the Arts - Opportunities and Challenges is relevant for artists and technologists and those engaged in interdisciplinary research and development at the boundaries between these disciplines.
    Keywords: User Interfaces and Human Computer Interaction ; Computer Appl. in Arts and Humanities ; Media Design ; Information Systems Applications (incl. Internet) ; Computer and Information Systems Applications ; Information Systems Applications (incl.Internet) ; Interactive Arts ; Digital Art ; Creativity and Virtual Reality ; Technology, Design and the Arts ; Open Access ; Collaborative Art and Design ; User interface design & usability ; Computer applications in the arts & humanities ; Graphical & digital media applications ; Information retrieval ; Internet searching ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYZ Human–computer interaction::UYZG User interface design and usability ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::U Computing and Information Technology::UG Graphical and digital media applications ; thema EDItEUR::U Computing and Information Technology::UN Databases::UNH Information retrieval
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    Springer Nature | Springer
    Publication Date: 2024-04-11
    Description: This open access book reports on cutting-edge electrical engineering and microelectronics solutions to foster and support digitalization in the semiconductor industry. Based on the outcomes of the European project iDev40, which were presented at the two first conference editions of the European Advances in Digital Transformation Conference (EADCT 2018 and EADTC 2019), the book covers different, multidisciplinary aspects related to digital transformation, including technological and industrial developments, as well as human factors research and applications. Topics include modeling and simulation methods in semiconductor operations, supply chain management issues, employee training methods and workplaces optimization, as well as smart software and hardware solutions for semiconductor manufacturing. By highlighting industrially relevant developments and discussing open issues related to digital transformation, the book offers a timely, practice-oriented guide to graduate students, researchers and professionals interested in the digital transformation of manufacturing domains and work environments.
    Keywords: Cyber-physical systems, IoT ; Engineering Economics, Organization, Logistics, Marketing ; Robotics and Automation ; Cyber-Physical Systems ; Industrial Management ; Industrial Automation ; Open Access ; Semantic Web Technologies ; Simulation-based Decision Making ; Cycle Time Modeling ; Automated Material Handling system ; Material Flow Simulation ; Digitalized Workplaces ; Automated Decision-making ; Cross Factory Decision-making ; Mixed Criticality Systems ; Digital twin ; Rapid Prototyping ; System dynamic simulation ; Return on quality ; iDev40 ; EADTC 2018 ; EADTC 2019 ; Electrical engineering ; Cybernetics & systems theory ; Engineering: general ; Management of specific areas ; Robotics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THR Electrical engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBC Engineering: general ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering::TJFM1 Robotics
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Multiple myeloma is a malignant disorder characterized by the proliferation of plasma cells. Much insight has been gained into the molecular pathways that lead to myeloma and indeed much more remains to be done. The understanding of these pathways is closely linked to their therapeutic implications and is stressed upon in the initial chapters. Recently, the introduction of newer agents such as bortezomib, lenalidomide, thalidomide, liposomal doxorubicin, etc. has led to a flurry of trials aimed at testing various combinations in order to improve survival. Higher response rates observed with these agents have led to their integration into induction therapies. The role of various new therapies vis a vis transplantation has also been examined. Recent advances in the management of plasmacytomas , renal dysfunction, dentistry as well as mobilization of stem cells in the context of myeloma have also found exclusive mention. Since brevity is the soul of wit our attempt has been to present before the reader a comprehensive yet brief text on this important subject.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Springer Nature | Springer
    Publication Date: 2022-05-02
    Description: This open access book takes a critical and international perspective to the mainstreaming of the Global Citizenship Concept and analyses the key issues regarding global citizenship education across the world. In that respect, it addresses a pressing need to provide further conceptual input and to open global citizenship agendas to diversity and indigeneity. Social and political changes brought by globalisation, migration and technological advances of the 21st century have generated a rise in the popularity of the utopian and philosophical idea of global citizenship. In response to the challenges of today’s globalised and interconnected world, such as inequality, human rights violations and poverty, global citizenship education has been invoked as a means of preparing youth for an inclusive and sustainable world. In recent years, the development of global citizenship education and the building of students’ global citizenship competencies have become a focal point in global agendas for education, international educational assessments and international organisations. However, the concept of global citizenship education still remains highly contested and subject to multiple interpretations, and its operationalisation in national educational policies proves to be challenging. This volume aims to contribute to the debate, question the relevancy of global citizenship education’s policy objectives and to enhance understanding of local perspectives, ideologies, conceptions and issues related to citizenship education on a local, national and global level. To this end, the book provides a comprehensive and geographically based overview of the challenges citizenship education faces in a rapidly changing global world through the lens of diversity and inclusiveness. ;
    Keywords: International and Comparative Education ; Social Justice, Equality and Human Rights ; Sociology of Education ; Environmental and Sustainability Education ; Educational Policy and Politics ; Human Rights ; Global social justice in education ; Global Citizenship Education GCE ; Preparing youth for a sustainable world ; 2030 Agenda for Sustainable Development ; United Nations ; Citizenship education ; Intercultural education ; Multicultural education ; Education for sustainable development ; Education for social justice ; Global competence ; International educational policies ; UNESCO ; Open Access ; Education ; Politics & government ; Social research & statistics ; Sustainability ; Educational strategies & policy ; bic Book Industry Communication::J Society & social sciences::JN Education ; bic Book Industry Communication::J Society & social sciences::JP Politics & government ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-04-14
    Description: This open access book provides a broad range of insights on market engineering and information management. It covers topics like auctions, stock markets, electricity markets, the sharing economy, information and emotions in markets, smart decision-making in cities and other systems, and methodological approaches to conceptual modeling and taxonomy development. Overall, this book is a source of inspiration for everybody working on the vision of advancing the science of engineering markets and managing information for contributing to a bright, sustainable, digital world. Markets are powerful and extremely efficient mechanisms for coordinating individuals’ and organizations’ behavior in a complex, networked economy. Thus, designing, monitoring, and regulating markets is an essential task of today’s society. This task does not only derive from a purely economic point of view. Leveraging market forces can also help to tackle pressing social and environmental challenges. Moreover, markets process, generate, and reveal information. This information is a production factor and a valuable economic asset. In an increasingly digital world, it is more essential than ever to understand the life cycle of information from its creation and distribution to its use. Both markets and the flow of information should not arbitrarily emerge and develop based on individual, profit-driven actors. Instead, they should be engineered to serve best the whole society’s goals. This motivation drives the research fields of market engineering and information management. With this book, the editors and authors honor Professor Dr. Christof Weinhardt for his enormous and ongoing contribution to market engineering and information management research and practice. It was presented to him on the occasion of his sixtieth birthday in April 2021. Thank you very much, Christof, for so many years of cooperation, support, inspiration, and friendship.
    Keywords: Computer Applications ; IT in Business ; e-Commerce/e-business ; Computer and Information Systems Applications ; e-Commerce and e-Business ; Information Systems ; Information Management ; Business Information Systems ; e-Services ; e-Finance ; Decision Support Systems ; Open Access ; Information technology: general issues ; Business mathematics & systems ; Business applications ; E-commerce: business aspects ; thema EDItEUR::U Computing and Information Technology::UB Information technology: general topics ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJQ Business mathematics and systems ; thema EDItEUR::U Computing and Information Technology::UF Business applications
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: This open access handbook brings together the latest research from a wide range of internationally influential scholars to analyze educational policy research from international, historical and interdisciplinary perspectives. By effectively breaking through the boundaries between countries and disciplines, it presents new theories, techniques and methods for contemporary education policy, and illustrates the educational policies and educational reform practices that various countries have introduced to meet the challenges of continuous change. Based on an analysis of the nature of education policy and education reform, this volume focuses on education reform and the concept of education quality. Adopting a historical and comparative perspective, it examines the dialectical relationship between education policy and education reform in various countries, assesses theoretical and practical issues in the process of moving from regulation to multiple governance in contemporary education administration, and explores the impact of globalization on national education reform and the interdependence between countries. In addition, it presents studies addressing educational policy research methodology from multiple perspectives. Highlighting the changes in national education macro policies, this volume comprehensively reveals the complex relationship between contemporary education reform and social change, and explores the links between contemporary social, political and economic systems and educational policy research and practice, offering a holistic portrait of macro trends in contemporary education reform. ; Brings together in a single volume a collection of international scholars from multiple disciplines Pushes the boundaries of education policy studies through its insightful analyses Equips readers to handle the complexities of policy research by employing critical thinking
    Keywords: Educational Policy and Politics ; International and Comparative Education ; Policy studies ; Educational reforms ; Educational research ; Educational knowledge ; Educational change ; The politics of education ; Contextual factors ; Policy analyses ; Policy process ; Public policy ; Open Access ; Educational strategies & policy ; Education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy ; bic Book Industry Communication::J Society & social sciences::JN Education
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-03-29
    Description: The world is currently undergoing an historic energy transition, driven by increasingly stringent decarbonisation policies and rapid advances in low-carbon technologies. The large-scale shift to low-carbon energy is disrupting the global energy system, impacting whole economies, and changing the political dynamics within and between countries. This open access book, written by leading energy scholars, examines the economic and geopolitical implications of the global energy transition, from both regional and thematic perspectives. The first part of the book addresses the geopolitical implications in the world’s main energy-producing and energy-consuming regions, while the second presents in-depth case studies on selected issues, ranging from the geopolitics of renewable energy, to the mineral foundations of the global energy transformation, to governance issues in connection with the changing global energy order. Given its scope, the book will appeal to researchers in energy, climate change and international relations, as well as to professionals working in the energy industry.
    Keywords: International Relations ; Energy Policy, Economics and Management ; Natural Resource and Energy Economics ; Climate Change/Climate Change Impacts ; Environmental Economics ; Earth System Sciences ; Energy transition geopolitics ; International decarbonisation policies ; Global warming ; Global energy system ; Geopolitics of the global energy transition ; Economic and political impacts of low-carbon technologies ; Power generation mix ; Geopolitical implications of global warming ; Governance of the global energy order ; Open Access ; International relations ; Energy technology & engineering ; Energy industries & utilities ; Environmental economics ; Climate change ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RNP Pollution and threats to the environment::RNPG Climate change
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Prostate cancer is one of the most common types of cancer in men and its treatment was constricted to surgery for confined state and androgen ablation for advanced disease until new options have become available. The present book covers a broad range of novel aspects of prostate cancer diagnosis, treatment and patient care, as well as new research on relevant cell biology. In detail, this special volume focusses on supportive modalities for prostate cancer patients, appropriate selection of novel therapeutic regimens, including inhibitors of steroidal synthesis, cytotoxic agents, as well as intermittent androgen suppression and the roles of prostate cancer stem cells and inflammatory processes.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book is oriented towards clinicians and scientists in the field of the management of patients with liver tumors. As many unresolved problems regarding primary and metastatic liver cancer still await investigation, I hope this book can serve as a tiny step on a long way that we need to run on the battlefield of liver tumors.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Hodgkin's Lymphoma is the book consisting of 11 chapters: Recent insights into the biology of Hodgkin's lymphoma, including historical aspects, epidemiology, pathophysiology, genetic defects, and prognostic indicators are explained in the intro chapters. After a translational chapter from tumor microenvironment to immunotherapeutic approach, treatment of early stage, advanced, and refractory Hodgkin's lymphoma are explained in the following chapters. MALT lymphoma and adverse effects of chemotherapy and radiotherapy in the affected patients are discussed in the subsequent chapters, while the final chapter is focused on survivorship in Hodgkin's lymphoma. The book is intended to present recent advances in the pathophysiology of Hodgkin's lymphoma as well as practical approach to diagnosis and management in clinical practice, which is hoped to be welcomed by the physicians, who wish to learn more about Hodgkin's lymphoma.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-03-29
    Description: This open access edited volume is a comparative effort to discern the short-term educational impact of the covid-19 pandemic on students, teachers and systems in Brazil, Chile, Finland, Japan, Mexico, Norway, Portugal, Russia, Singapore, Spain, South Africa, the United Kingdom and the United States. One of the first academic comparative studies of the educational impact of the pandemic, the book explains how the interruption of in person instruction and the variable efficacy of alternative forms of education caused learning loss and disengagement with learning, especially for disadvantaged students. Other direct and indirect impacts of the pandemic diminished the ability of families to support children and youth in their education. For students, as well as for teachers and school staff, these included the economic shocks experienced by families, in some cases leading to food insecurity and in many more causing stress and anxiety and impacting mental health. Opportunity to learn was also diminished by the shocks and trauma experienced by those with a close relative infected by the virus, and by the constrains on learning resulting from students having to learn at home, where the demands of schoolwork had to be negotiated with other family necessities, often sharing limited space. Furthermore, the prolonged stress caused by the uncertainty over the resolution of the pandemic and resulting from the knowledge that anyone could be infected and potentially lose their lives, created a traumatic context for many that undermined the necessary focus and dedication to schoolwork. These individual effects were reinforced by community effects, particularly for students and teachers living in communities where the multifaceted negative impacts resulting from the pandemic were pervasive. This is an open access book.
    Keywords: Open Access ; Education and Covid-19 ; Educational Inequality ; Education Disruption ; Education Policy ; Education Technology ; Comparative Education ; Remote learning ; Schooling during a pandemic ; Distance teaching ; post-pandemic educational policies ; Homeschooling during Pendemic ; understanding Inequities in Instruction and Learning ; Education in the times of Covid-19 ; Unequal Impacts of COVID-19 ; bic Book Industry Communication::J Society & social sciences::JN Education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy ; bic Book Industry Communication::J Society & social sciences::JN Education::JNZ Study & learning skills: general ; bic Book Industry Communication::J Society & social sciences::JN Education::JNK Organization & management of education ; thema EDItEUR::J Society and Social Sciences::JN Education ; thema EDItEUR::J Society and Social Sciences::JN Education::JNF Educational strategies and policy ; thema EDItEUR::J Society and Social Sciences::JN Education::JNZ Study and learning skills: general ; thema EDItEUR::J Society and Social Sciences::JN Education::JNK Educational administration and organization
    Language: English
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    Springer Nature | Springer
    Publication Date: 2024-04-08
    Description: This open access textbook offers a practical guide into research ethics for undergraduate students in the social sciences. A step-by-step approach of the most viable issues, in-depth discussions of case histories and a variety of didactical tools will aid the student to grasp the issues at hand and help him or her develop strategies to deal with them. This book addresses problems and questions that any bachelor student in the social sciences should be aware of, including plagiarism, data fabrication and other types of fraud, data augmentation, various forms of research bias, but also peer pressure, issues with confidentiality and questions regarding conflicts of interest. Cheating, ‘free riding’, and broader issues that relate to the place of the social sciences in society are also included. The book concludes with a step-by-step approach designed to coach a student through a research application process.
    Keywords: Research Ethics ; Methodology of the Social Sciences ; Psychological Methods/Evaluation ; Moral Philosophy and Applied Ethics ; Biotechnology ; Psychological Methods ; conceptualizing research ethics ; research ethics in the social sciences ; definition of plagiarism ; factors that facilitate plagiarism ; ghostwriting ; measures to counter plagiarism ; fabrication and cheating ; research bias ; science's self-correction ; publication bias ; Open Access ; Ethics & moral philosophy ; Philosophy of science ; Social research & statistics ; Psychological methodology ; bic Book Industry Communication::H Humanities::HP Philosophy::HPQ Ethics & moral philosophy ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHB Sociology::JHBC Social research & statistics ; bic Book Industry Communication::J Society & social sciences::JM Psychology::JMB Psychological methodology ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTQ Ethics and moral philosophy ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics ; thema EDItEUR::J Society and Social Sciences::JM Psychology::JMB Psychological methodology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Oncogenomics and Cancer Proteomics - Novel Approaches in Biomarkers Discovery and Therapeutic Targets in Cancer presents comprehensive reviews of the most common cancers from bench to bedside applications by an international team of experts. This book will contribute to the scientific and medical community by providing up-to-date discoveries of oncogenomics and their potential applications in cancer translational research. It is intended for students, scientists, clinicians, oncologists and health professionals working in cancer research.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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