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  • thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics  (133)
  • thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)  (119)
  • Chemistry
  • Inorganic Chemistry
  • ddc:330
  • IntechOpen  (273)
  • Berlin : Schmidt  (16)
Collection
Keywords
Publisher
Language
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  • 1
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    Gene Therapy (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: The aim of this book is to cover key aspects of existing problems in the field of development and future perspectives in gene therapy. Contributions consist of basic and translational research, as well as clinical experiences, and they outline functional mechanisms, predictive approaches, patient-related studies and upcoming challenges in this stimulating but also controversial field of gene therapy research. This source will make our doctors become comfortable with the common problems of gene therapy and inspire others to delve a bit more deeply into a topic of interest.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 2
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    Mutations in Human Genetic Disease (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Different types of mutation can vary in size, from structural variants to single base-pair substitutions, but what they all have in common is that their nature, size and location are often determined either by specific characteristics of the local DNA sequence environment or by higher order features of the genomic architecture. The genomes of higher organisms are now known to contain "pervasive architectural flaws" in that certain DNA sequences are inherently mutation prone by virtue of their base composition, sequence repetitivity and/or epigenetic modification. In this volume, a number of different authors from diverse backgrounds describe how the nature, location and frequency of different types of mutation causing inherited disease are shaped in large part, and often in remarkably predictable ways, by the local DNA sequence environment.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 3
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    Recent Advances in Nanofabrication Techniques and Applications (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Nanotechnology has experienced a rapid growth in the past decade, largely owing to the rapid advances in nanofabrication techniques employed to fabricate nano-devices. Nanofabrication can be divided into two categories: "bottom up" approach using chemical synthesis or self assembly, and "top down" approach using nanolithography, thin film deposition and etching techniques. Both topics are covered, though with a focus on the second category. This book contains twenty nine chapters and aims to provide the fundamentals and recent advances of nanofabrication techniques, as well as its device applications. Most chapters focus on in-depth studies of a particular research field, and are thus targeted for researchers, though some chapters focus on the basics of lithographic techniques accessible for upper year undergraduate students. Divided into five parts, this book covers electron beam, focused ion beam, nanoimprint, deep and extreme UV, X-ray, scanning probe, interference, two-photon, and nanosphere lithography.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 4
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    Mineralogy (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Mineralogy includes thirteen chapters that discuss the methodology of specific mineralogical methods, the composition of minerals from different igneous rocks, and the composition of minerals from different sedimentary rocks.It contains detailed mineralogical studies from Africa, Asia, and Europe. Chapters present different scientific mineralogical methods and detailed descriptions of minerals from different magmatic and sedimentary rocks.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNV Chemistry of minerals, crystals and gems
    Language: English
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  • 5
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    Benzimidazole (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Benzimidazole is a comprehensive survey of the known and new methods of benzimidazole synthesis, the spectral and theoretical aspects of existing benzimidazole derivatives, and the anticancer properties of a new class of benzimidazole derivatives. This book examines aspects and newer mechanisms of benzimidazoles containing heterocyclic moiety. Chapters report on anticancer properties of benzimidazole derivatives, novel methods of synthesis of benzimidazoles, versatile nature of the benzimidazoles, spectral and theoretical studies of benzimidazole derivatives, and medicinal importance and pharmacological aspects of benzimidazole derivatives.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 6
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    Flow Cytometry (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: "Flow Cytometry - Recent Perspectives" is a compendium of comprehensive reviews and original scientific papers. The contents illustrate the constantly evolving application of flow cytometry to a multitude of scientific fields and technologies as well as its broad use as demonstrated by the international composition of the contributing author group. The book focuses on the utilization of the technology in basic sciences and covers such diverse areas as marine and plant biology, microbiology, immunology, and biotechnology. It is hoped that it will give novices a valuable introduction to the field, but will also provide experienced flow cytometrists with novel insights and a better understanding of the subject.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 7
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    Electrospinning and Electrospraying (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book focuses on the recent advancements in the process parameters, research, and applications of electrospinning and electrospraying. The first chapter introduces the techniques and the effect of the parameters on the morphology of the nanofiber and nanoparticles and then the subsequent chapters focus on the applications of these techniques in different areas. This book will attract a broad audience including postgraduate students and industrial and academic investigators in sciences and engineering who wish to enhance their understanding of the emerging technologies and use this book as reference.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 8
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    New Advances in Powder Technology (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: This book discusses the basics of powder metallurgy and its interesting applications along with various powder manufacturing techniques. It also reviews the wettability of powders and the properties and applications of various metal powders. It is a great tool for understanding the various parameters of sintering techniques. The book includes seven chapters that describe basic concepts of powder metallurgy, sintering, and related applications.
    Keywords: wettability ; microstructure ; composite ; iron ; porosity ; sintering ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 9
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    Genetic Polymorphisms (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: The objective of this Genetic Polymorphisms book is to rehighlight and provide few updates on the role of genetic polymorphisms in medicine and agriculture, which void emerging opinion on "full death" of genetic polymorphisms as useful genetic markers. Chapters presented here demonstrate the future benefit of SNPs in many genetic studies as well as prognosis disease and diagnosis.
    Keywords: atherosclerosis, cancer, hepatocellular carcinoma, colorectal cancer, multiple sclerosis, microrna ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 10
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    Green Chemistry (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Green Chemistry - New Perspectives is at the frontiers of this continuously evolving interdisciplinary science, and publishes research that attempts to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The book covers all aspects of green chemistry, including chemical synthesis, nano synthesis, eco-friendly processes, biomass, extraction techniques, environmental remediation, and energy, making it a unique reference resource. This will continue to encourage scientists around the world to develop novel synthetic methods or improve the existing ones to circumvent some of the problems and favours all aspects of green chemistry. This book is intended for academia, professionals, scientists, as well as graduate and undergraduate students without any geographical limitations.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 11
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    Electrodeposited Nanowires and their Applications (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The book offers a new and complex perspective on the fabrication and use of electrodeposited nanowires for the design of efficient and competitive applications. While not pretending to be comprehensive, the book is addressing not only to researchers specialized in this field, but also to Ph.D. students, postdocs and experienced technical professionals.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 12
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    The Delivery of Nanoparticles (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Nanoparticle is a general challenge for today's technology and the near future observations of science. Nanoparticles cover mostly all types of sciences and manufacturing technologies. The properties of this particle are flying over today scientific barriers and have passed the limitations of conventional sciences. This is the reason why nanoparticles have been evaluated for the use in many fields. InTech publisher and the contributing authors of this book in nanoparticles are all overconfident to invite all scientists to read this new book. The book's potential was held until it was approached by the art of exploring the most advanced research in the field of nano-scale particles, preparation techniques and the way of reaching their destination. 25 reputable chapters were framed in this book and there were alienated into four altered sections; Toxic Nanoparticles, Drug Nanoparticles, Biological Activities and Nano-Technology.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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  • 13
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    New Research on Silicon (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The knowledge of fundamental silicon questions and all aspects of silicon technology gives the possibility of improvement to both initial silicon material and devices on silicon basis. The articles for this book have been contributed by the much respected researchers in this area and cover the most recent developments and applications of silicon technology and some fundamental questions. This book provides the latest research developments in important aspects of silicon including nanoclusters, solar silicon, porous silicon, some technological processes, and silicon devices and also fundamental question about silicon structural perfection. This book is of interest both to fundamental research and to practicing scientists and also will be useful to all engineers and students in industry and academia.
    Keywords: graphene, thin films, dft, membrane, mems, raman spectroscopy ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 14
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    Density Functional Theory (2024)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book presents a comprehensive overview of density functional theory (DFT), from its basics to its practical application and implementation. It also discusses the breakthroughs in the field and the complete integration of physical and chemical aspects. It examines both orbital and time-dependent functions along with their variations according to semiquantitative analysis. The book also discusses analytical and computational techniques and principles, considering the classical and quantum approaches. Also covered are important topics such as HOMO (highest occupied molecular orbital), LUMO (lowest unoccupied molecular orbital), MEP (minimum energy paths), KS-DFT (Kohn-Sham density functional theory), UHFD (Unrestricted Hartree-Fock-Dirac), and Gaussian methods.
    Keywords: thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 15
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    Magnetic Materials and Magnetic Levitation (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Magnetic materials are important materials for high-tech areas and technological development, which are being classified not only based on their origin but also by the nature of processing, properties, functions, and applications. This book presents an overview of the different types of new magnetic materials and hybrid structures that exhibit different magnetic phenomena and interesting properties. The reported materials are studied theoretically and experimentally, which are the building blocks of all technological innovations. Topics such as magnetic levitation are given for industrial applications. The chapters of the book provide a key description of magnetic materials. This book is suitable for undergraduate and graduate students and professionals including engineers, scientists, researchers, technicians, and technology managers. This book gives an idea to readers for scientific innovation in this field.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 16
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    Biosensors (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Nowadays, the implementation of novel technological platforms in biosensor-based developments is primarily directed to the miniaturization of analytical systems and lowering the limits of detection. Rapid scientific and technological progress enables the application of biosensors for the online detection of minute concentrations of different chemical compounds in a wide selection of matrixes and monitoring extremely low levels of biomarkers even in living organisms and individual cells. This book, including 16 chapters, characterizes the present state of the art and prospective options for micro and nanoscale activities in biosensors construction and applications.
    Keywords: graphene, immunoassay, fluorescence, microfluidics, electrochemistry, nitric oxide ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 17
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    Recent Applications in Sol-Gel Synthesis (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Versatility, extended compositional ranges, better homogeneity, lesser energy consumption, and requirement of nonexpensive equipments have boosted the use of sol-gel process on top of the popularity in the synthesis of nanosystems. The sol-gel technique has not only revolutionized oxide ceramics industry and/or material science but has also extended widely into multidimensional applications. The book Recent Applications in Sol-Gel Synthesis comprises 14 chapters that deal mainly with the application-oriented aspects of the technique. Sol-gel prepared metal oxide (MO) nanostructures like nanospheres, nanorods, nanoflakes, nanotubes, and nanoribbons have been employed in biomedical applications involving drug deliveries, mimicking of natural bone, and antimicrobial activities. The possibility of controlling grain size in aerogel and preparation of ultrahigh-temperature ceramic (UHTC)-based materials, fluorescent glasses, ultraviolet photosensors, and photocatalysts have been discussed in detail by the experts in the field. The usefulness of sol-gel materials as active GRIN, as textile finisher, and as leather modifier with water-repellent and oil-resistive properties would be an incentive for researchers keen to pursue the field.
    Keywords: tio2, zinc oxide, water, mass spectrometry, fluorescence, thin films ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 18
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    Chromosomal Abnormalities (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Chromosomes are vital components of genetic material, and, as such, distruption or changes to the structure of chromosomes can result in different health problems and deficits. This book explains chromosomal abnomalities and their effects on living organisms, including humans and plants. Classical and molecular cytogenetics techniques have a considerable number of potential applications, especially in clinical trials and biomedical diagnosis, making them a strong and insightful complement to other molecular and genomic approaches. Chapters cover topics including Down syndrome, fetal ultrasounds, acute myeloid leukemia, and Phelan-McDermid syndrome, among others.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 19
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    Point Mutation (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book concerns the signatures left behind in chromosomes by the forces that drive DNA code evolution in the form of DNA nucleotide substitutions. Since the genetic code predetermines the molecular basis of life, it could have been about any aspect of biology. As it happens, it is largely about recent adaptation of pathogens and their human host. Nine chapters are medically oriented, two are bioinformatics-oriented and one is technological, describing the state of the art in synthetic point mutagenesis. What stands out in this book is the increasing rate at which DNA data has been amassed in the course of the past decade and how knowledge in this vibrant research field is currently being translated in the medical world.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 20
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    Gene Expression and Regulation in Mammalian Cells (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Sixty years after the "central dogma," great achievements have been developed in molecular biology. We have also learned the important functions of noncoding RNAs and epigenetic regulations. More importantly, whole genome sequencing and transcriptome analyses enabled us to diagnose specific diseases. This book is not only intended for students and researchers working in laboratory but also physicians and pharmacists. This volume consists of 14 chapters, divided into 4 parts. Each chapter is written by experts investigating biological stresses, epigenetic regulation, and functions of transcription factors in human diseases. All articles presented in this volume by excellent investigators provide new insights into the studies in transcriptional control in mammalian cells and will inspire us to develop or establish novel therapeutics against human diseases.
    Keywords: cancer, dna methylation, inflammation, breast cancer, apoptosis, aging ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 21
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    Nanowires (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: One dimensional nanoscale structures such as nanowires have drawn extensive research interests in recent years. The size miniature brings unique properties to nanowires due to quantum confinement. The large surface-to-volume ratio renders nanowires with high sensitivity to surface effects. The unique geometrical advantages and properties facilitate the utilization of nanowires in nano-electronics. InTech scientific publisher has initialized a series of books focusing on fundamental research in nanowires, which largely boosted the widespread of knowledge among the research society. This book is intended to provide an updated review on the applications of various nanowires and the associated advancements in synthesis and properties characterization. The topics include recent progress in metal oxide nanowires, silicon nanowires, carbon based nanotubes and nanowires.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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  • 22
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    Piezoelectricity (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Scientifically defined in 1880 by the Curie brothers, piezoelectricity - from the Greek piezein, meaning to press (squeeze), and ilektron, meaning amber, a material with electrostatic properties - is a phenomenon with many applications. The related piezoelectric materials have been undergoing a long-lasting evolution over the years until today. The field of organic and inorganic piezoelectric materials is continuously expanding in terms of new substances used, new structures, and new applications. The seven chapters of this book present modern aspects and technological advances in the field of piezoelectric materials and applications. To present a balanced view of the field, some chapters focus on new piezoelectric materials and structures, while others examine interesting applications of piezoelectric sensors, energy harvesters, and actuators.
    Keywords: aluminum nitride, machine learning, biotechnology, sensors, thin film, nanocellulose ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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  • 23
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    Mutagenesis and Mitochondrial-Associated Pathologies (2022)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Reactive oxygen species (ROS) and DNA double-strand breaks can result from mitochondrial defects and external sources, such as ionizing radiation. If not repaired properly, pathogenic mutations are generated. Human diseases resulting from inherited mitochondrial defects manifest in organs that physiologically require a high level of ATP synthesis. These diseases are clinically challenging, but new experimental clinical therapies include gene editing and mitochondrial transplants. Pathogenic ROS-associated cellular damage includes DNA double-strand breaks, and mouse models are now available to study multiple repair pathways. This book discusses the clinical manifestations of mitochondrial diseases in both the eye and the kidney, and presents new insights into double-strand break repair pathways and developmental phenotypes of g-ray-associated ontogenic mutations of Drosophila melanogaste.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 24
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    Nanofiber Research (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book titled Nanofiber Research - Reaching New Heights contains a number of latest research results on growth and developments on material fibers in nanoscale. It is a promising novel research area that has received a lot of interest in recent years. This book includes interesting reports on cutting-edge science and technology related to synthesis, morphology, control, self-assembly and prospective application of nanofibers. I hope that the book will lead to systematization of nanofiber science, creation of new nanofiber research field and further promotion of nanofiber technology. This potentially unique work offers various approaches on the implementation of nanofibers. As it is widely known, nanotechnology presents the control of matter at the nanoscale and nano-dimensions within few nanometers, whereas this exclusive phenomenon enables us to regulate and control novel applications with nanofibers. This book presents an overview of recent and current nanofibers fundamental, significant applications and implementation research worldwide. It examined the methods of nanofiber synthesis, types of fibers used and potential applications associated with nanofiber researches. It is an important booklet for research organizations, governmental research centers, academic libraries and R&D affianced in recent research and development of nanofibers.
    Keywords: electrospinning, tissue engineering, nanofibers, nanoparticles, drug delivery, chitosan ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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  • 25
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    Smart Nanoparticles Technology (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: In the last few years, Nanoparticles and their applications dramatically diverted science in the direction of brand new philosophy. The properties of many conventional materials changed when formed from nanoparticles. Nanoparticles have a greater surface area per weight than larger particles which causes them to be more reactive and effective than other molecules. In this book, we (InTech publisher, editor and authors) have invested a lot of effort to include 25 most advanced technology chapters. The book is organised into three well-heeled parts. We would like to invite all Nanotechnology scientists to read and share the knowledge and contents of this book.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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  • 26
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    Reviews on Selected Topics of Telomere Biology (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Telomeres, located at the ends of linear chromosomes, are essential for genome stability and integrity. Advances in telomere researches have linked telomere dysfunction with cellular aging and a number of age-related human diseases. Recent studies further expanded our knowledge of telomere functions - telomeres are shown to be important for microbial pathogen virulence and telomere proteins have important non-telomeric cellular functions. This book includes current opinions on selected aspects of telomere research and their implication, in hope to help us focus better on future studies and enhance our research progress.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 27
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    On the Properties of Novel Superconductors (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Since the discovery of superconductivity, a great number of theoretical and experimental efforts have been made to describe this new phase of matter that emerged in many body systems. In this regard, theoretical models have been presented; the most famous of which was the BCS theory that can only describe conventional superconductors. With the discovery of new class superconductors, the superconducting mechanism became a new challenge in the field of condensed matter physics. This unexpected discovery opened a new area in the history of superconductivity, and experimental researchers started trying to find new compounds in this class of superconductors. These superconductors are often characterized by the anisotropic character in the superconducting gap function with nodes along a certain direction in the momentum space. Since the pairing interaction has an important role in the superconducting gap structure, its determination is very important to explain the basic pairing mechanism.In this regard, this book includes valuable theoretical and experimental discussions about the properties of superconductors. Here you will find valuable research describing the properties of unconventional superconductors.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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  • 28
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    Molecular Mechanisms of the Aging Process and Rejuvenation (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: Numerous studies had been performed to elucidate the mechanisms of aging and to achieve rejuvenation, with some success reported in recent years. However, at present, the findings from those studies are not sufficient to resolve the issue of aging. This book presents an overview of recent topics on cellular aging and rejuvenation. In the early chapters, the molecular mechanisms of aging via the activities of clock and ion channel proteins, in addition to overall aspects, are discussed. In the latter part, the aging of the skin, immune system, and brain is discussed. This book will prove useful for those studying or developing new drugs to counter the aging process and will encourage the development of novel ideas for rejuvenation.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Nanomaterials (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This edited book, Nanomaterials - Toxicity and Risk Assessment, is a collection of current research and information on numerous advances on the toxicity and hazardous effects of nanomaterials, including theoretical and experimental approaches as well as nanotechnology applications in the field of medicine, pharmacology, and the manufacture of nanoscale materials. Based on the large number of nanomaterial applications, a careful understanding of the associated systemic and local toxicity is critically required.
    Keywords: nanoparticles, cancer, inflammation, oxidative stress, apoptosis, drug delivery ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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    Viral Gene Therapy (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: The development of technologies that allow targeting of specific cells has progressed substantially in recent years for several types of vectors, particularly viral vectors, which have been used in 70% of gene therapy clinical trials. Particular viruses have been selected as gene delivery vehicles because of their capacities to carry foreign genes and their ability to efficiently deliver these genes associated with efficient gene expression. This book is designed to present the most recent advances in viral gene therapy
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Analytical Liquid Chromatography (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book consists of several selected chapters on important subjects in modern high-performance liquid chromatography (HPLC) and ultra-performance liquid chromatography (UPLC). The content addresses aspects related to both improvements in the mainstream HPLC/UPLC technology and utilization, as well as developments of exploratory new materials and equipment. The book presents useful details about the presented subjects as well as describes new applications and/or relevant case studies for each subject. It is addressed to a large audience of analytical chemists involved in separation science. Each chapter is authored by scientists with considerable field and academic experience.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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    Antisense Therapy (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Antisense Therapy offers a comprehensive, state-of-the art perspective on the role of antisense therapy in the treatment of human disease, with a special focus on cancer. Use of antisense oligonucleotides is a growing field of pharmaceutical and biotech companies and research programs for treatment of several diseases. This book summarizes and presents the best updates, therapeutic principles, methods, and applications in the field and offers meaningful information to move treatment discovery forward.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Progress in Understanding Cystic Fibrosis (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Congenital defects in humans are of greater concern, and in that line, cystic fibrosis (CF) has been one of the most complex diseases posing treatment challenge till date. Though it is a chronic condition, CF is closely associated with dysfunction of various organ systems of the human body, which in turn results in secondary infections by microbes. Decades of research by scientists worldwide has narrowed down the cause of CF to a single target gene. But the complexity of the disease is the prime impediment to finding a single-shot cure. Fortunately, the multidisciplinary approach toward understanding and management of the CF condition has certainly increased the level of life expectancy among CF patients. In particular, the "omics" and the "systems biology" approach have greatly widened the focal area for better understanding of the disease. This book includes a collection of interesting chapters contributed by eminent scientists around the world who have been striving to improve the life of those affected by CF.
    Keywords: biofilm, pseudomonas aeruginosa, inflammation, wound healing, microbiome, insulin ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Advances in Graphene Science (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Graphene is proving to be the magic material of the 21th century. It is widely accepted that it is the strongest material ever studied and can be an efficient substitute for silicon. Besides, fascinating properties of graphene, such as the highest electrical conductivity among the discovered substances, have dramatically shocked science and technology world. Graphene is a carbon based layer with high atomic density. Its extraordinary characteristics such as extremely high mechanical strength, hardness, and adjustable thermal and electrical conductivity, as well as excellent surface and optical feature through chemical marking, have received great deal of attention by many researchers. This book collects new advances of this interesting nanomaterial.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Industrial Applications of Ionic Liquids (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Due to their very low volatility, high thermal stability, and ability to dissolve a wide variety of compounds, ionic liquids appear to meet the rigorous criteria for industrial applications. Among other uses, ionic liquids appear to be efficient for gas capture, biomass pretreatment, separation problems, and electrochemistry. They are also used in electrolytes, as lubricants, catalysts, or as antistatic agents. This book discusses the various uses of ionic liquids. Chapters discuss such topics as the use of ionic liquids in batteries, new mono, di, and trimeric imidazolium and pyridinium ionic liquids as catalysts in organic chemistry, the physico-chemical properties of ionic liquid-substituted double-network gels for industrial applications, the use of paramagnetic ionic liquids in magnetic resonance imaging, the compatibility of filter materials used with ionic liquids, and the development of low-friction ion gels for industrial applications.
    Keywords: Physics ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Carbon Nanotubes (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book has been outlined as follows: A review on the literature and increasing research interests in the field of carbon nanotubes. Fabrication techniques followed by an analysis on the physical properties of carbon nanotubes. The device physics of implemented carbon nanotubes applications along with proposed models in an effort to describe their behavior in circuits and interconnects. And ultimately, the book pursues a significant amount of work in applications of carbon nanotubes in sensors, nanoparticles and nanostructures, and biotechnology. Readers of this book should have a strong background on physical electronics and semiconductor device physics. Philanthropists and readers with strong background in quantum transport physics and semiconductors materials could definitely benefit from the results presented in the chapters of this book. Especially, those with research interests in the areas of nanoparticles and nanotechnology.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Genotoxicity and Mutagenicity (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This edited book, “Genotoxicity and Mutagenicity - Mechanisms and Test Methods”, aims to present the latest developments from different fields, highlighting the detrimental influence that mutagenic and genotoxic agents inflict on DNA and how antimutagenic and anticarcinogenic modulators are able to reduce the negative impact of such toxic agents on living species.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Gene Expression (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Gene expression is dependent on multiple steps, including transcription, RNA processing, and translation. Importantly, recent studies revealed that gene expression is regulated by chromatin structures and non-coding RNA profiles. Elucidating the molecular mechanisms may contribute to the development of novel therapeutics for aging-related diseases, including cancer and neurodegenerative diseases. This book provides a comprehensive overview of gene expression and its role in human disease. It consists of nine chapters organized into two sections on molecular mechanisms in controlling gene expression and the relationships between transcriptional control and human disease.
    Keywords: Pre-clinical medicine: basic sciences ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Next Generation Sequencing (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Telomere (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book, Telomere - A Complex End of a Chromosome, is organized into nine chapters containing the latest aspects of the current knowledge about the structure of telomeres and the crucial role that telomerase plays not only in maintaining chromosomal stability but also in relation to cell immortality, cell instability, and cancer biology. We now appreciate that these unusual complexes of DNA and proteins we all know as "telomeres" are dynamic and key structures that depend on telomerase and other cellular factors for continuance. Regulation of telomere activity is a dynamic area of current research, and new insights into telomeres and their role in aging and cancer, among other biological functions and pathologies, appear regularly in the scientific world. However, one fact is more than understandable in this difficult biological conundrum: the end of the telomere story is far from being totally unraveled.
    Keywords: cancer, oxidative stress, biomarkers, chemotherapy, human health, transplantation ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Epigenetics to Optogenetics (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Epigenetics, which deals with the study of heritable gene expression that takes place independent of changes in DNA sequence, and optogenetics, which deals with the study of genes expressed under the influence of light, are two emerging areas of study and research that have contributed immensely to our current knowledge of mechanisms and disease processes in humans. These disciplines are interrelated in the broader picture of biology and one can be used to change or modify the other. The complexity of the techniques involved in these disciplines often leads to a lack of proper understanding by researchers from other disciplines and the scientific community at large. As such, this book provides simple and easy-to-follow explanations of some of the most exciting areas of research in these disciplines.
    Keywords: Pre-clinical medicine: basic sciences ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    In Vivo and Ex Vivo Gene Therapy for Inherited and Non-Inherited Disorders (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Ongoing advances in pharmaceutical biotechnology have paved the way to ground-breaking new biological therapeutic modalities, offering the possibility of a durable curative approach for a number of life-threatening diseases, for which the medical need is as yet unmet. Over the past decades, gene therapy has seen a massive transformation from a proof-of-concept approach to a clinical reality culminating in the regulatory approval of state-of-the-art products in the European Union and in the United States. This book captures some of the scientific progresses notably in gene transfer technologies and translational development of in vivo and ex vivo gene therapy interventions in the treatment of a broad range of complex and debilitating non-inherited and inherited disorders such as: human immunodeficiency virus 1 (HIV-1) infection, cancer, cystic fibrosis, hereditary retinopathies, haemophilia B, cardiac diseases, and chronic liver fibrosis.
    Keywords: nanoparticles, heart failure, drug delivery, vaccine, hiv, cardiomyopathy ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Inelastic X-Ray Scattering and X-Ray Powder Diffraction Applications (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book illustrates a few exemplary scientific topics addressed through the use of two complementary x-ray scattering techniques: inelastic x-ray scattering and x-ray powder diffraction. These scattering methods are the focus of the two main sections of this book. These sections are subdivided into chapters discussing specific applications. The general aim of this volume is providing a concise overview of the opportunities disclosed by these two experimental methods, providing some guidance for scientists picking up this field and, hopefully, inspiring more mature scientists towards the achievement of new advances in this area.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Recent Advances in Chemical Kinetics (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Recent Advances in Chemical Kinetics provides a comprehensive overview of several types of chemical reactions. It includes six chapters that discuss solvent catalysis, customized flow reactors, p-conjugation in kinetics, kinetics of autoxidation, molecular chameleon for cations and anions, and internal clocks of atoms.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
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    Carbon Nanotubes (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book shows the recent advances of the applications of carbon nanotubes (CNTs), in particular, the polymer functionalized carbon nanotubes. It also includes a comprehensive description of carbon nanotubes’ preparation, properties, and characterization. Therefore, we have attempted to provide detailed information about the polymer-carbon nanotube composites. With regard to the unique structure and properties of carbon nanotubes, a series of important findings have been reported. The unique properties of carbon nanotubes, including thermal, mechanical, and electrical properties, after polymer functionalization have been documented in detail. This book comprises 18 chapters. The chapters include different applications of polymer functionalization CNTs, e.g. photovoltaic, biomedical, drug delivery, gene delivery, stem cell therapy, thermal therapy, biological detection and imaging, electroanalytical, energy, supercapacitor, and gas sensor applications.
    Keywords: graphene, nanocomposites, nanomaterials, additive manufacturing, 3d printing, polymers ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Fundamental Aspects of DNA Replication (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: DNA replication, the process of copying one double stranded DNA molecule to produce two identical copies, is at the heart of cell proliferation. This book highlights new insights into the replication process in eukaryotes, from the assembly of pre-replication complex and features of DNA replication origins, through polymerization mechanisms, to propagation of epigenetic states. It also covers cell cycle control of replication initiation and includes the latest on mechanisms of replication in prokaryotes. The association between genome replication and transcription is also addressed. We hope that readers will find this book interesting, helpful and inspiring.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    DNA Methylation (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Epigenetics is one of the most exciting and rapidly developing areas of modern genetics with applications in many disciplines from medicine to agriculture. The most common form of epigenetic modification is DNA methylation, which plays a key role in fundamental developmental processes such as embryogenesis and also in the response of organisms to a wide range of environmental stimuli. Indeed, epigenetics is increasing regarded as one of the major mechanisms used by animals and plants to modulate their genome and its expression to adapt to a wide range of environmental factors. This book brings together a group of experts at the cutting edge of research into DNA methylation and highlights recent advances in methodology and knowledge of underlying mechanisms of this most important of genetic processes. The reader will gain an understanding of the impact, significance and recent advances within the field of epigenetics with a focus on DNA methylation.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Gene Therapy (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Gene therapy is becoming a promising technology for the management of many human diseases. Hereditary and acquired disorders can both be tackled using the technique of gene therapy. This book provides detailed, up-to-date topics addressing basic principles of gene therapy and discussing some of the challenges encountered by scientists in developing this relatively novel technology. The development of new and efficient gene transfer vectors is of utmost importance in the progress of the field of gene therapy. Both viral and non-viral vectors are extensively discussed. A detailed chapter elaborates the problem of host immune rejection of transplanted donor cells or engineered tissue that can be avoided using the encapsulation of transgenic cells, thus avoiding the use of drugs that achieve immunosuppression.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Genetic Diversity (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Genetic diversity is the entire amount of genes and genotypes in a group of organisms and is of vital importance for their adaptation to different living conditions. If, for example, all humans were identical, the extinction of the entire kind could happen very fast. Let us care and nourish differences! The goal of this book is to present some of the contemporary thoughts on understandings of the genetic diversity patterns and their altering in a changing world. The book is aimed to the ones inspired to study and contemplate genetic diversity and to the audience beyond any frames.
    Keywords: environment, biodiversity, mutation, polymorphism, hiv-1, legislation ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Osteogenesis (2021)
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    Publication Date: 2024-03-31
    Description: This book provides an in-depth overview of current knowledge about Osteogenesis, including molecular mechanisms, transcriptional regulators, scaffolds, cell biology, mechanical stimuli, vascularization and osteogenesis related diseases. Hopefully, the publication of this book will help researchers in this field to decide where to focus their future efforts, and provide an overview for surgeons and clinicians who wish to be directed in the developments related to this fascinating subject.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Plasmid (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book captures in a single volume the wealth of information on the plasmid structure, function, and biology of all organisms that have been examined to date. Plasmids exhibit wide variations in size, modes of replication and transmission, host ranges, and the genes they carry and have provided us with a great understanding of basic life principles at the molecular level. Written by experts in the field, this book is a valuable source of up-to-date information, delivering the latest impacts on studies in the areas of plasmid types, genomes, purification analysis, and expression of recombinant proteins in bacteria. Plasmid utilization in the synthesis of plasmid-based vaccines, plasmids as genetic tools, and their applications in ecology and the evolutionary process are also covered. This book is a single source of valuable information for instructors and students in advanced undergraduate and graduate courses on plasmids. It will also appeal to researchers seeking to find new relationships between biological processes that are linked by plasmids to the environment.
    Keywords: immunotherapy, calcium, infectious diseases, vaccines, antigen, rna ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Updates in Advanced Lithography (2021)
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    Publication Date: 2024-04-05
    Description: Advanced lithography grows up to several fields such as nano-lithography, micro electro-mechanical system (MEMS) and nano-phonics, etc. Nano-lithography reaches to 20 nm size in advanced electron device. Consequently, we have to study and develop true single nanometer size lithography. One of the solutions is to study a fusion of top down and bottom up technologies such as EB drawing and self-assembly with block copolymer. In MEMS and nano-photonics, 3 dimensional structures are needed to achieve some functions in the devices for the applications. Their formation are done by several methods such as colloid lithography, stereo-lithography, dry etching, sputtering, deposition, etc. This book covers a wide area regarding nano-lithography, nano structure and 3-dimensional structure, and introduces readers to the methods, methodology and its applications.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Perovskite and Piezoelectric Materials (2021)
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    Publication Date: 2024-04-05
    Description: Investigating in the area of perovskite materials and the fabrication of devices for properties in optoelectronics, we have presented a brief outline of perovskite materials. The authors present a fairly comprehensive arrangement of this very active area of research, with its past changes and present position and outlooks. Discussions are presented regarding photocatalysis, fabrication of solar cell devices and their stability, lead-free materials, as well as thermoelectric and piezoelectric applications. In view of the present status of perovskite materials, I am assured that each chapter of the book will be of boundless encouragement for researchers, scientists, and academicians working in this field.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Gene Therapy (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: The Gene Therapy field is living exciting times after more than 20 years of poor results. Scientist and clinicians working in the gene therapy field have encountered many problems in the past that are now starting to be solved. The development of safer and more efficient gene transfer vectors and the advances on the cell therapy field have open new opportunities to tackle different diseases. The aim of this book is to bring together information about the different gene therapy tools, the clinical successes of gene therapy and the future applications.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Syntheses and Applications of Carbon Nanotubes and Their Composites (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Carbon nanotubes are rolled up graphene sheets with a quasi-one-dimensional structure of nanometer-scale diameter. In these last twenty years, carbon nanotubes have attracted much attention from physicists, chemists, material scientists, and electronic device engineers, because of their excellent structural, electronic, optical, chemical and mechanical properties. More recently, demand for innovative industrial applications of carbon nanotubes is increasing. This book covers recent research topics regarding syntheses techniques of carbon nanotubes and nanotube-based composites, and their applications. The chapters in this book will be helpful to many students, engineers and researchers working in the field of carbon nanotubes.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Apoptosis and Medicine (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book looks at the latest research studies on apoptosis in medicine. It is divided into three sections for convenient and easy reading. The first section which comprises two chapters is an introduction of the subject of apoptosis to the uninitiated. The second section which comprises a single solitary chapter looks at apoptosis in normal physiology during bone resorption under mechanical stress. The third and the final section reviews apoptosis in a number of pathological conditions with an emphasis on cancer.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Molecular Cloning (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: The development of molecular cloning technology in the early 1970s created a revolution in the biological and biomedical sciences that extends to this day. The contributions in this book provide the reader with a perspective on how pervasive the applications of molecular cloning have become. The contributions are organized in sections based on application, and range from cancer biology and immunology to plant and evolutionary biology. The chapters also cover a wide range of technical approaches, such as positional cloning and cutting edge tools for recombinant protein expression. This book should appeal to many researchers, who should find its information useful for advancing their fields.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Health Problems in Down Syndrome (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book provides a concise yet comprehensive source of current information on Down syndrome. It focuses on exciting areas of research on diseases associated with Down syndrome. Inside, you will find state-of-the-art information on diseases associated with Down syndrome; improvement of cognitive skills in Down syndrome; and research approaches on Down syndrome. Although aimed primarily at research workers on Down syndrome, we hope that the appeal of this book extends beyond the narrow confines of academic interest and reaches a wider audience, especially parents, relatives, and health care providers who work with infants and children with Down syndrome.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Nanowires (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: One-dimensional nanostructures, such as nanowires, have drawn extensive research interests in the recent years. The smaller size brings unique properties to the nanowires due to the finite size effect (quantum confinement effects). The unique geometrical features of the nanowires bring their utilization in many practical applications in the recent advanced technology. This book provides an updated review on fabrication, properties, and applications of various nanowires. This book is aimed to provide solid foundation of nanowires to the students, scientists, and engineers working in the field of material science and condensed matter physics.
    Keywords: mechanical properties, nanocomposite, surface modification, solar cells, self-assembly, photovoltaics ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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    Cytogenetics (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This edited book, Cytogenetics - Classical and Molecular Strategies for Analysing Heredity Material, presents recent advances in the field of cytogenetics, paying special attention to methodological achievements developed worldwide that have driven the field forward. The contributors clearly discuss several concepts and approaches useful for understanding chromosomal structure and function at its various levels, highlighting chromosomes as visible carriers of heredity material.
    Keywords: chromatin, aneuploidy, chromosomes, next-generation sequencing, in vitro fertilization, acute lymphoblastic leukemia ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Genetic Diversity in Microorganisms (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Genetic Diversity in Microorganisms presents chapters revealing the magnitude of genetic diversity of microorganisms living in different environmental conditions. The complexity and diversity of microbial populations is by far the highest among all living organisms. The diversity of microbial communities and their ecologic roles are being explored in soil, water, on plants and in animals, and in extreme environments such as the arctic deep-sea vents or high saline lakes. The increasing availability of PCR-based molecular markers allows the detailed analyses and evaluation of genetic diversity in microorganisms. The purpose of the book is to provide a glimpse into the dynamic process of genetic diversity of microorganisms by presenting the thoughts of scientists who are engaged in the generation of new ideas and techniques employed for the assessment of genetic diversity, often from very different perspectives. The book should prove useful to students, researchers, and experts in the area of microbial phylogeny, genetic diversity, and molecular biology.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    DNA Replication and Related Cellular Processes (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Since the discovery of the DNA structure researchers have been highly interested in the molecular basis of genome inheritance. This book covers a wide range of aspects and issues related to the field of DNA replication. The association between genome replication, repair and recombination is also addressed, as well as summaries of recent work of the replication cycles of prokaryotic and eukaryotic viruses. The reader will gain an overview of our current understanding of DNA replication and related cellular processes, and useful resources for further reading.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Nondestructive Testing Methods and New Applications (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Nondestructive testing enables scientists and engineers to evaluate the integrity of their structures and the properties of their materials or components non-intrusively, and in some instances in real-time fashion. Applying the Nondestructive techniques and modalities offers valuable savings and guarantees the quality of engineered systems and products. This technology can be employed through different modalities that include contact methods such as ultrasonic, eddy current, magnetic particles, and liquid penetrant, in addition to contact-less methods such as in thermography, radiography, and shearography. This book seeks to introduce some of the Nondestructive testing methods from its theoretical fundamentals to its specific applications. Additionally, the text contains several novel implementations of such techniques in different fields, including the assessment of civil structures (concrete) to its application in medicine.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    State-of-the-Art of Quantum Dot System Fabrications (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The book "State-of-the-art of Quantum Dot System Fabrications" contains ten chapters and devotes to some of quantum dot system fabrication methods that considered the dependence of shape, size and composition parameters on growth methods and conditions such as temperature, strain and deposition rates. This is a collaborative book sharing and providing fundamental research such as the one conducted in Physics, Chemistry, Material Science, with a base text that could serve as a reference in research by presenting up-to-date research work on the field of quantum dot systems.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Fingerprints in the Optical and Transport Properties of Quantum Dots (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The book "Fingerprints in the optical and transport properties of quantum dots" provides novel and efficient methods for the calculation and investigating of the optical and transport properties of quantum dot systems. This book is divided into two sections. In section 1 includes ten chapters where novel optical properties are discussed. In section 2 involve eight chapters that investigate and model the most important effects of transport and electronics properties of quantum dot systems This is a collaborative book sharing and providing fundamental research such as the one conducted in Physics, Chemistry, Material Science, with a base text that could serve as a reference in research by presenting up-to-date research work on the field of quantum dot systems.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Phylogenetics (2023)
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    Publication Date: 2024-03-31
    Description: Phylogenetics aims to study the evolutionary relatedness of living organisms in our planet. Its application is extended to the key areas such as evolution, classification and taxonomy of living organisms; ecology, diversity, and conservation biology of agrobiocenosis; monitoring of pathogen spread, outbreaks and source of transmissions, forensic analyses, etc. Historically, phylogenetics studies were prevalently based on morphological features of species that helped to classify the 'Tree of Life' on Earth. Modern phylogenetics studies, however, rely more heavily on DNA sequences. In this Phylogenetics book, we aimed to present readers the latest developments in phylogenetics studies that highlight multi-kingdom systems, reticulated evolution and conservation biology of living organisms as well as 'omics'-based phylogenetics advances.
    Keywords: bacteria, convergence, species diversity, cytogenetics, archaea ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Selected Topics in Plasma Physics (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book is planned to introduce the advances topics of plasma physics for research scholars and postgraduate students. This book deals with basic concepts in plasma physics, non-equilibrium plasma modeling, space plasma applications, and plasma diagnostics. It also provides an overview of the linear and nonlinear aspects of plasma physics. Chapters cover such topics as plasma application in space propulsion, microwave–plasma interaction, plasma antennas, solitary waves, and plasma diagnostic techniques.
    Keywords: Plasma physics ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Genetics and Etiology of Down Syndrome (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book provides a concise yet comprehensive source of current information on Down syndrome. Research workers, scientists, medical graduates and paediatricians will find it an excellent source for reference and review. This book has been divided into four sections, beginning with the Genetics and Etiology and ending with Prenatal Diagnosis and Screening. Inside, you will find state-of-the-art information on: 1. Genetics and Etiology 2. Down syndrome Model 3. Neurologic, Urologic, Dental & Allergic disorders 4. Prenatal Diagnosis and Screening Whilst aimed primarily at research workers on Down syndrome, we hope that the appeal of this book will extend beyond the narrow confines of academic interest and be of interest to a wider audience, especially parents and relatives of Down syndrome patients.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Advances in Diverse Industrial Applications of Nanocomposites (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Nanocomposites are attractive to researchers both from practical and theoretical point of view because of combination of special properties. Many efforts have been made in the last two decades using novel nanotechnology and nanoscience knowledge in order to get nanomaterials with determined functionality. This book focuses on polymer nanocomposites and their possible divergent applications. There has been enormous interest in the commercialization of nanocomposites for a variety of applications, and a number of these applications can already be found in industry. This book comprehensively deals with the divergent applications of nanocomposites comprising of 22 chapters.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Targets in Gene Therapy (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book aims at providing an up-to-date report to cover key aspects of existing problems in the emerging field of targets in gene therapy. With the contributions in various disciplines of gene therapy, the book brings together major approaches: Target Strategy in Gene Therapy, Gene Therapy of Cancer and Gene Therapy of Other Diseases. This source enables clinicians and researchers to select and effectively utilize new translational approaches in gene therapy and analyze the developments in target strategy in gene therapy.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Gene Editing (2021)
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    Publication Date: 2024-03-31
    Description: Gene-editing technologies (e.g., ZFNs, TALENs, and CRISPRs/Cas9) have been extensively used as tools in basic research. They are further applied in manufacturing agricultural products, food, industrial products, medicinal products, etc. Particularly, the discovery of medicinal products using gene-editing technologies will open a new era for human therapeutics. Though there are still many technical and ethical challenges ahead of us, more and more products based on gene-editing technologies have been approved for marketing. These technologies are promising for multiple applications. Their development and implications should be explored in the broadest context possible. Future research directions should also be highlighted. In this book, the applications, perspectives, and challenges of gene-editing technologies are significantly demonstrated and discussed.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Redox Chemistry (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Redox reactions are involved in biochemistry, energy, corrosion, and much more. In both biology and electrochemistry, the redox reaction is complex and varied. For example, redox shuttles in supercapacitors show aspects of molecular electrochemistry applied to electrode porosity. In pseudocapacitors, the formalism associated with their electrochemical response requires investigation and formalism. Similarly, the simple definition of redox potential opens fundamental questions about its measurement in solutions without supporting salts. This book illustrates the variety of redox reactions in its examination of the importance of redox molecules in the development of new electrical energy storage devices.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRH Electrochemistry and magnetochemistry
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    Carbon Nanotubes (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Carbon Nanotubes are among the strongest, toughest, and most stiff materials found on earth. Moreover, they have remarkable electrical and thermal properties, which make them suitable for many applications including nanocomposites, electronics, and chemical detection devices. This book is the effort of many scientists and researchers all over the world to bring an anthology of recent developments in the field of nanotechnology and more specifically CNTs. In this book you will find: - Recent developments in the growth of CNTs- Methods to modify the surfaces of CNTs and decorate their surfaces for specific applications- Applications of CNTs in biocomposites such as in orthopedic bone cement- Application of CNTs as chemical sensors- CNTs for fuelcells- Health related issues when using CNTs
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Ferroelectrics and Their Applications (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Ferroelectricity is a symptom of inevitable electrical polarization changes in materials without external electric field interference. Ferroelectricity is a phenomenon exhibited by crystals with a spontaneous polarization and hysteresis effects associated with dielectric changes when an electric field is given. Our fascination with ferroelectricity is in recognition of a beautiful article by Itskovsky, in which he explains the kinetics of a ferroelectric phase transition in a thin ferroelectric layer (film). We have been researching ferroelectric materials since 2001. There are several materials known for their ferroelectric properties. Barium titanate and barium strontium titanate are the most well known. Several others include tantalum oxide, lead zirconium titanate, gallium nitride, lithium tantalate, aluminium, copper oxide, and lithium niobate. There is still a blue ocean of ferroelectric applications yet to be expounded. It is and hopefully always will be a bright future.
    Keywords: chitosan, mathematical model, ceramics, biopolymers, polarization, biocomposites ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Advances in Nanofibers (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Book Advances in Nanofibers is a research publication that covers original research on developments within the Nanofibers field of study. The book is a collection of reviewed scholarly contributions written by different authors. Each scholarly contribution represents a chapter and each chapter is complete in itself but related to the major topics and objectives. The target audience comprises scholars and specialists in the field.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Mitochondrial Diseases (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Mitochondria are crucial organelles for any cell type. Mitochondria take responsibility for not only energy production but also regulation of cell death, also called apoptosis; calcium storage; and heat production. Therefore, mitochondrial disease is implicated in the mode of action of many harmful factors for cells such as drugs and environmental contaminants, dysfunction of the oxygen transport system, malnutrition, intense exercise, and genetic variations. This book presents up-to-date knowledge about mitochondrial disease and its complex relation to some diseases such as cardiac failure, cancer, and Alzheimer's and Parkinson's diseases. This book will, therefore, be essential for readers who are interested in life sciences, especially in medicine.
    Keywords: heart failure, aging, metabolism, calcium, heart, cancer ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Clinical Flow Cytometry (2021)
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    Publication Date: 2024-03-31
    Description: "Clinical Flow Cytometry - Emerging Applications" contains a collection of reviews and original papers that illustrate the relevance of flow cytometry for the study of specific diseases and clinical evaluations. The chapters have been contributed by authors from a wide variety of countries showing the broad application and importance of this technology in medicine. Examples include chapters on autoimmune disease, cancer, and the evaluation of new drugs. The book is intended to give newcomers a helpful introduction, but also to provide experienced flow cytometrists with novel insights and a better understanding of clinical cytometry.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Muscular Dystrophies (2023)
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    Publication Date: 2024-03-31
    Description: Skeletal muscle is a highly plastic organ that is modulated by various pathways controlling protein turnover. Muscle loss is common in muscular dystrophy, in which marked loss of various proteins such as the dystrophin-glycoprotein complex occurs around muscle fibers. This book provides a comprehensive overview of the various muscular dystrophies, including characteristics, diagnosis, and classification. General treatment of drugs (e.g. corticosteroids) and physical therapy for muscular dystrophies are discussed. In addition, current applications for cell and tissue engineering using muscle stem cells or gene therapy are introduced. This book also deals with the recent advances in appropriate models of drug screening using cell cultures or mammalian organs in vitro in this field.
    Keywords: muscular dystrophy, duchenne muscular dystrophy, quality of life, pathology, physical activity, adipogenesis ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Senescence (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: In the second half of the twentieth century, life expectancy was prolonged, and the number of elderly people increased. The effect of population aging increases in the frequency of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, epilepsy, and stroke. Also, a higher incidence of infections, autoimmune diseases, and malignant cancers is observed in elderly people. The aging process is difficult to define. Are physiological changes in elderly people controlled by specific genes? Is aging process a pathophysiology affecting different organs with different severity? Finding answers to these questions may help prevent age-related diseases and improve the quality of life of old people. This book was made as a compendium on contemporary challenges in senescence.
    Keywords: aging, inflammation, oxidative stress, alzheimer’s disease, apoptosis, epigenetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Advances in the Study of Genetic Disorders (2021)
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    Publication Date: 2024-03-31
    Description: The studies on genetic disorders have been rapidly advancing in recent years as to be able to understand the reasons why genetic disorders are caused. The first Section of this volume provides readers with background and several methodologies for understanding genetic disorders. Genetic defects, diagnoses and treatments of the respective unifactorial and multifactorial genetic disorders are reviewed in the second and third Sections. Certainly, it is quite difficult or almost impossible to cure a genetic disorder fundamentally at the present time. However, our knowledge of genetic functions has rapidly accumulated since the double-stranded structure of DNA was discovered by Watson and Crick in 1956. Therefore, nowadays it is possible to understand the reasons why genetic disorders are caused. It is probable that the knowledge of genetic disorders described in this book will lead to the discovery of an epoch of new medical treatment and relieve human beings from the genetic disorders of the future.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Nanocrystals (2021)
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    Publication Date: 2024-04-05
    Description: This book contains a number of latest research developments on nanocrystals. It is a promising new research area that has received a lot of attention in recent years. Here you will find interesting reports on cutting-edge science and technology related to synthesis, morphology control, self-assembly and application of nanocrystals. I hope that the book will lead to systematization of nanocrystal science, creation of new nanocrystal research field and further promotion of nanocrystal technology for the bright future of our children.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
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    Phase Equilibria With Supercritical Carbon Dioxide (2023)
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    Publication Date: 2024-04-05
    Description: We are living in a critical time, both for humanity and the planet, which has led us to look for more sustainable formulas to interact with the environment. One of the important changes in the design and operation of chemical processes is the search for environmentally friendly technologies. Supercritical carbon dioxide has been revealed as a promising environmentally friendly solvent that is energy efficient, selective and capable of reducing waste, making it a promising alternative to conventional organic solvents. However, reliable and versatile mathematical models of phase equilibrium thermodynamics are needed for the use of supercritical carbon dioxide in process design and viability studies. This book reviews experimental procedures for obtaining high-pressure phase equilibria data and describes the phase diagrams of binary mixtures and some thermodynamic models capable of determining the conditions of phase equilibria at high pressures. These concepts are applied to the components of the transesterification reaction of rac-2-pentanol with a vinyl ester, which is important in the pharmaceutical industry because (S)-2-pentanol can be obtained as a reaction product. This product is a key intermediate in the synthesis of drugs against Alzheimer’s disease.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
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    Protein Phosphorylation in Human Health (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: 15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human health and diseases. Detailed and comprehensive text with excellent figure illustration.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Chromatin Remodelling (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: The term "chromatin remodelling" is widely used to describe changes in chromatin structure which is controlled by histone-modifying enzymes, chromatin remodelling complexes, non-histone DNA-binding proteins and noncoding RNAs. Many human diseases such as cancer, various genetic syndromes, autism and infectious disease have been linked to the disruption of these control processes by genetic, environmental or microbial factors. Therefore, to unravel the mechanisms by which they operate is one of the most exciting and rapid developing fields of modern biology and will contribute to new ways in treatment of these diseases. The chapters in this book will focus on recent advances in our understanding of the mechanisms that govern the dynamic structural of chromatin, thereby providing important insights into gene regulation, DNA repair, and human diseases.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    DNA Replication (2023)
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    Publication Date: 2024-03-31
    Description: The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. However, it also created conceptual shortcuts, beliefs and misunderstandings that obscure the natural phenomena, hindering its better understanding. The deep conviction that no human knowledge is perfect, but only perfectible, should function as a fair safeguard against scientific dogmatism and enable open discussion. With this aim, this book will offer to its readers 30 chapters on current trends in the field of DNA replication. As several contributions in this book show, the study of DNA will continue for a while to be a leading front of scientific activities.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Colloids (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Colloids are submicron particles that are ubiquitous in both natural and industrial products. Colloids and colloidal systems play a significant role in human health as well as commercial and industrial situations. Colloids have important applications in medicine, sewage disposal, water purification, mining, photography, electroplating, agriculture, and more.This book gathers recent research from experts in the field of colloids and discusses several aspects of colloid morphology, synthesis, and applications. The book is divided into three sections that cover different techniques for the synthesis of colloids, the structure, dynamic and stability of colloids, and applications of colloidal particles, respectively.
    Keywords: adsorption, optimization, cellulose, biofuels, copper, dentistry ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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    Genetic Diversity and Disease Susceptibility (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Polymorphism or variation in DNA sequence can affect individual phenotypes such as color of skin or eyes, susceptibility to diseases, and response to drugs, vaccines, chemicals, and pathogens. Especially, the interfaces between genetics, disease susceptibility, and pharmacogenomics have recently been the subject of intense research activity. This book is a self-contained collection of valuable scholarly papers related to genetic diversity and disease susceptibility, pharmacogenomics, ongoing advances in technology, and analytic methods in this field. The book contains nine chapters that cover the three main topics of genetic polymorphism, genetic diversity, and disease susceptibility and pharmacogenomics. Hence, this book is particularly useful to academics, scientists, physicians, pharmacists, practicing researchers, and postgraduate students whose work relates to genetic polymorphisms.
    Keywords: cancer, pharmacogenetics, polymorphisms, molecular markers, drug development, pharmacokinetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Laser Ablation (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Shortly after the demonstration of the first laser, the most intensely studied theoretical topics dealt with laser-matter interactions. Many experiments were undertaken to clarify the major ablation mechanisms. At the same time, numerous theoretical studies, both analytical and numerical, were proposed to describe these interactions. These studies paved the ways toward the development of numerous laser applications, ranging from laser micro- and nanomachining to material analysis, nanoparticle and nanostructure formation, thin-film deposition, etc. Recently, more and more promising novel fields of laser applications have appeared, including biomedicine, catalysis, photovoltaic cells, etc. This book intends to provide the reader with a comprehensive overview of the current state of the art in laser ablation, from its fundamental mechanisms to novel applications.
    Keywords: pulsed laser deposition, nanoparticles, nanocomposites, thin films, mathematical modeling, hydrodynamics ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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    RNA Processing (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: RNA functions broadly as informational molecule, genome, enzyme and machinery for RNA processing. While these functions reflect ancient activities, they also remain vital components of contemporary biochemical pathways. In eukaryotic cells RNA processing impacts the biogenesis of RNA molecules of essentially every shape and function. The collection of articles in this volume describes the current state of understanding of the broad array of RNA processing events in animal and plant cells, key unanswered questions, and cutting edge approaches available to address these questions. Some questions discussed in this volume include, how viruses subvert the RNA processing machinery of the host cell, how the coordination of co-transcriptional RNA processing is regulated at the level of chromatin, the status of RNA processing in plant organelles, and how micro RNA machinery is biosynthesized and regulated.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Application of Nanotechnology in Drug Delivery (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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    Covalent Organic Frameworks (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: In recent decades, artificial porous structures have attracted increasing enthusiasm from researchers inspired by the fascinating molecular pores in nature and their unique biological functions. Although substantial achievements in porous materials have been realized, the construction of topologically designed pores is still challenging. Recently, the emergence of covalent organic frameworks (COFs), which are constructed based on organic and polymer chemistry, has made it possible to design artificial pores with controlled pore size, topology and interface properties. COFs are crystalline porous materials constructed by the precise reticulation of organic building blocks via dynamic covalent bonds. Distinct from non-covalent interactions which tend to produce isostructures, covalent bonds enable accurate pore design owing to their predetermined reaction pathways. In addition, the appropriate polycondensation of organic building units enables the formation of extended two-dimensional (2D) and three-dimensional (3D) polymer architectures with periodically ordered skeletons and well-defined pores. With their large surface area, tailorable structures, and tunable chemistry, COFs are regarded as potentially superior candidates for various applications including catalysis, energy storage and conversion, mass transport and biotechnology. This book examines the historic achievement of COFs, providing clear and comprehensive guidance for researchers on their structural design, synthetic protocols and functional exploration.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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    Heterojunctions and Nanostructures (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The current book entitled Heterojunctions and Nanostructures is divided into two sections. In Section 1, the chapters are related to topological insulators where their theoretical aspects, their current experiments, and their applications are presented. A few presented topics are, among others, the topological phases of matter, band topology of insulators and also of Weyl semimetals, transport properties of 3D topological insulator quantum wires and the influence of disorder, transport properties of quasi-1D (and 2D) topological surface states, quantum coherence, and topological insulator thin-film Hall bar device. In Section 2, the chapters are related to light devices such as laser diodes and their fabrication techniques. This section includes, among others, topics such as semiconductor quantum nanowire laser diodes, solutions of Schrodinger equation in nanostructures, numerical methods, light-to-electricity conversion devices, photoexcited carrier transportation process in quantum wells and quantum dots, growth mode and characterization of heterostructure of large lattice mismatch, and photoionization cross section.
    Keywords: quantum confinement, boundary condition, disorder, dirac fermions ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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    Methylation (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Alterations in the normal DNA methylation processes are known to have major consequences for embryonic development and are associated with congenital defects, autoimmunity, aging and malignant transformation. The main purpose of this book is to provide information about the importance of methylation mechanisms in human health and disease. The book, covers the basic mechanism of DNA and protein methylation, aiming at the advanced undergraduate and graduate biomedical students and researchers working in the epigenetic area. The textbook chapters provide background as well as advanced information in the methylation area. On the other hand, it provide readers with both classical and relevant recent discoveries that have been made in the field, pointing out pathways where questions remain.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Nanomaterials Based Gas Sensors for SF6 Decomposition Components Detection (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The insulating medium used in gas-insulated switchgear is SF6 gas, which has been widely used in substations. Energy generated by discharge will cause the composition of SF6 and generate characteristic component gases. Diagnosing the insulation defect through analyzing the decomposed gases of SF6 by chemical gas sensors is the optimal method due to its advantages. Carbon nanotubes, TiO2 nanotubes and graphene are chosen as the gas-sensing materials to build specific gas sensors for detecting each kind of SF6 decomposed gases and then enhance the gas sensitivity and selectivity by material modification. The properties and preparation methods are introduced in this book. The author studied the micro-adsorption mechanism and macro-gas sensing properties by theoretical calculation and sensing experiment.
    Keywords: carbon nanotubes, density functional theory, graphene, adsorption, sensing mechanism ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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    Fluoride (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Fluoride covers a continuum of topics that are frequently studied in the broad area of fluoride (F) research. It provides an overview of the primary sources of environmental fluoride in typical high-fluoride environments and demonstrates the transitions and transformations that emerge and culminate in hydro-geochemical interactions that result in fluoride-fouling of large portions of the world’s water and agricultural resources. This way, the book pinpoints the connection between F enrichment of water sources and the prevalence of endemic fluorosis in certain areas of the world. In order to contribute to a better understanding of the global fluoride problem, new fluoride detection and quantification technologies are proposed with an in-depth analysis of emerging trends in the use of portable user-friendly devices in point-of-use measurements of water fluoride. This has been presented against the backdrop of a robust overview of traditional fluoride quantification methodologies that are still in wide application among the scientific communities. In addressing fluoride toxicities, which are not limited to dental and skeletal dilapidations, the authors have explored the role of natural antioxidants in ameliorating physiological fluoride-induced noxious effects in mammalian systems. Nonetheless, since community dependence on high-fluoride water due to a lack of alternative clean water sources remains to be the principal pathway of human fluoride over-exposure, a review chapter on F mitigation techniques applied all over the world is incorporated aiming at providing a succinct overview of water defluoridation techniques and strategies being used to combat the impacts of human F overexposure around the globe. Since every cloud has a silvery lining, the possibility of using ammonium fluorides as a novel reagent in mineral processing has been considered convenient industrial fluorinating agents, which present the possibility of complete regeneration that is not afforded by the reagents presently used in decomposing silicon component of the ores.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
    Language: English
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    Magnetometers (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The stars as well as the Earth and its defects, materials, and gases have magnetic fields. To measure these fields, magnetometers are used. This book includes contributions from a variety of experts that examine the typical properties, uses, novel developments, and calibration of sensing magnetic devices. Chapters cover topics related to recent advances in the modeling and application of magnetometers.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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    Current Progress in Biological Research (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Current Progress in Biological Research presents new insights into key topics from different areas of the biological sciences. Some of the topics covered in the book are antibiotic susceptibility, genomic rearrangement, historical biogeography, biogeographic patterns, endemism and the use of microorganisms for pest control. The book is an interesting collection of 16 original research articles written by respected experts in their fields. It is hoped that readers will be stimulated and challenged by the contents of this book.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    The Role of Matrix Metalloproteinase in Human Body Pathologies (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair. However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body.
    Keywords: matrix metalloproteinases, mmps, biomarkers, heart failure, risk factors, atherosclerosis ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Progress in Fine Particle Plasmas (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: In the field of plasma physics, plasmas (including charged fine particles) have been actively studied for more than 40 years, and special features of wave phenomena, self-organizations of the particles, potential formations, fluid-like motions of the particles, generations of fine particles in the plasmas, etc. have been investigated. Here, these plasmas are called “fine particle plasmas”, which are also called “dusty plasmas” and “complex plasmas”. This book intends to provide the reader with the recent progress of studies of fine particle plasmas from the viewpoints of wide and interdisciplinary directions, such as self-organized fine particles, Coulomb crystal formation, behaviors of fine particles, their stability, and syntheses of nano-sized particles in reactive plasmas. Further, the phenomena of dense grain particles and the effects of massive neutrinos in galaxy clustering are included.
    Keywords: Condensed matter physics (liquid state & solid state physics) ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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    Nanomechanics (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: In recent years, nanotechnology is the basis for the development of modern production. This determined the urgency of the intensive development of the new direction of mechanics and nanomechanics, for the scientific description of nanotechnological processes and the solution of several topical nanotechnology problems. Topics included in the book cover a wide range of research in the field of nanomechanics: thermomass theory of nanosystems; deformation of nanomaterials; interface mechanics of assembly carbon nanotube; nanomechanics on surface; molecular interactions and transformations; nanomechanical sensors, nanobeams, and micromembranes; nanostructural organic and inorganic materials; green synthesis of metallic nanoparticles. The main goal of these works is the establishment of the nanosystem macroparameter dependence on its nanoparameters using nanomechanics. This book will be useful for engineers, technologists, and researchers interested in methods of nanomechanics and in advanced nanomaterials with complex behavior and their applications.
    Keywords: mechanical properties, carbon nanotubes, finite element method, thermal conductivity, green synthesis, interface ; thema EDItEUR::P Mathematics and Science::PH Physics::PHF Materials / States of matter::PHFC Condensed matter physics (liquid state and solid state physics)
    Language: English
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