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  • bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences  (482)
  • thema EDItEUR::P Mathematics and Science::PS Biology, life sciences  (404)
  • bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology  (372)
  • integrated flood risk management
  • MDPI - Multidisciplinary Digital Publishing Institute  (1,259)
  • American Chemical Society
  • Blackwell Publishing Ltd
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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This reprint is the printed edition of the Special Issue published in Materials. The reprint provides an overview on current international research activities in the field of advanced pulse laser machining technology. It covers fundamental and applied aspects and collects contributions of renowned scientists from academics and industries working in the fields of laser processing, materials science, physics, chemistry, and engineering in order to foster the current knowledge and present new ideas for future applications and new technologies.
    Keywords: multi-beam micromachining ; beam splitting ; invar ; shadow masks ; OLED ; nanosecond laser ; direct laser interference patterning ; design of experiments ; central composite design ; morphological filtering ; surface texture homogeneity ; micro structuring ; bearing steel ; dual laser beam processing ; excited state absorption ; semiconducting thin films ; stimulated emission depletion ; femtosecond laser ; silicon ; amorphization ; crystallization ; spectroscopic imaging ellipsometry ; transmission electron microscopy ; atomic force microscopy ; laser ablation ; ultrafast ; re-deposition ; fs-laser writing ; waveguides ; element redistribution ; Soret effect ; diffusion competition effects ; ultra-short pulses ; double pulses ; burst processing ; MHz bursts ; GHz bursts ; X-ray emission ; micromachining ; dose rate ; X-ray spectrum ; ultrafast laser ; laser ; ultrashort pulse ; plasma ; X-ray ; Bremsstrahlung ; resonance absorption ; burst ; bi-burst ; beam shaping ; squared top-hat ; fs-laser ; laser surface structuring ; laser-induced periodic surface structures ; micro-channels ; glass ; ultrafast laser processing ; Bessel beam ; X-ray emission hazards ; ultrashort pulsed laser ; radiation protection ; industrial applications ; protection housing ; ambient dose rate ; pulsed laser ; laser micromachining ; mechanical shutter ; solenoid shutter ; electro-optic modulator shutter ; opening time ; lifetime ; X-ray energies ; X-ray dose rate ; laser printing ; laser-induced forward transfer (LIFT) ; digital manufacturing ; additive manufacturing ; printing of materials ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 2
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: Landscapes and cultural heritage have faced many challenges over time, including modifications and degradation that appear with time, overlaps with other challenges not previously observed, and the influence of cities and management. One of the most visible and globally discussed challenges is climate change. Therefore, there is an urgent need to launch initiatives to tackle climate change and other current challenges from the perspective of landscape and cultural heritage protection. This Special Issue presents selected papers of studies conducted in relation to the 28th Conference on the Series of Garden Art and Historical Dendrology entitled “Climate Change and Current Challenges for Landscapes and Cultural Heritage” that was held on 28 and 29 October 2021. This collection serves as a platform for the exchange of experiences among researchers from different scientific domains.
    Keywords: nature reserves ; landscape fragmentation ; north–south transitional zone ; spatial differentiation ; Qinling–Daba Mountains ; habitat quality ; water dams ; Krakow fortress ; climate change ; environmental management ; cultural heritage conservation ; urban densification ; prefabricated housing estates ; spatial devastation ; protection of urban layout ; Cracow ; climate change mitigation ; cultural heritage ; urban renewal ; urban parks ; therapeutic landscapes ; climate resilience ; vernacular heritage ; climate narratives ; climate adaptation ; climate stories ; courtyard ; urban green infrastructure ; urban pattern ; supervised classification ; ecosystem services (ES) ; urban cemeteries ; biocultural diversity (BCD) ; urban green infrastructure (UGI) ; questionnaire survey ; Leipzig ; Łódź ; sensory gardens ; urban green spaces ; aromatic herbs ; plant smell memory ; stress ; human wellbeing in urban areas ; restorative environments ; history of gardens ; castle garden ; goosefoot avenue ; star-shaped garden layout ; Austro-Hungarian Empire ; Transylvania as part of Romania ; green infrastructure ; resilience management ; biodiversity ; scenario analysis ; cellular automata model ; historic psychiatric hospitals ; therapeutic landscape ; green therapy ; horticulture therapy ; historical commons ; human cultural heritage ; local development ; landscape values ; rainwater management ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Language: English
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  • 3
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Wildfire risk can be perceived as the combination of wildfire hazards (often described by likelihood and intensity) with the susceptibility of people, property, or other valued resources to that hazard. Reflecting the seriousness of wildfire risk to communities around the world, substantial resources are devoted to assessing wildfire hazards and risks. Wildfire hazard and risk assessments are conducted at a wide range of scales, from localized to nationwide, and are often intended to communicate and support decision making about risks, including the prioritization of scarce resources. Improvements in the underlying science of wildfire hazard and risk assessment and in the development, communication, and application of these assessments support effective decisions made on all aspects of societal adaptations to wildfire, including decisions about the prevention, mitigation, and suppression of wildfire risks. To support such efforts, this Special Issue of the journal Fire compiles articles on the understanding, modeling, and addressing of wildfire risks to homes, water resources, firefighters, and landscapes.
    Keywords: wildfire risk ; object-oriented image analysis ; Sentinel-2 ; fire behavior ; flammap ; wildfire management ; water supply ; erosion ; wildfire containment ; Potential fire Operational Delineations ; Monte Carlo simulation ; transmission risk ; WUI ; fire ; defensible space ; prescribed fire ; community vulnerability ; fire suppression costs ; Zillow ; wildfire ; predictive modeling ; fire spread model ; Monte Carlo ; spatial modeling ; area difference index ; statistics ; precision ; recall ; principal components analysis ; risk assessment ; structure loss ; wildland–urban interface ; mitigation ; mapping ; land use ; disaster ; fire spread models ; surrogate modeling ; sensitivity analysis ; global sensitivity analysis ; colour coding ; communication ; forest fire ; ordinal categorization ; palette ; risk ; firefighter safety ; safe separation distance ; safety zones ; LCES ; Google Earth Engine ; lidar ; LANDFIRE ; Landsat ; GEDI ; parcel-level risk ; post-fire analysis ; risk mitigation ; rapid assessment ; natural hazards ; fuels ; fire hazard ; remote sensing ; LiDAR ; Sentinel ; modeling ; simulation ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: This book introduces novel results on mathematical modelling, parameter identification, and automatic control for a wide range of applications of mechanical, electric, and mechatronic systems, where undesirable oscillations or vibrations are manifested. The six chapters of the book written by experts from international scientific community cover a wide range of interesting research topics related to: algebraic identification of rotordynamic parameters in rotor-bearing system using finite element models; model predictive control for active automotive suspension systems by means of hydraulic actuators; model-free data-driven-based control for a Voltage Source Converter-based Static Synchronous Compensator to improve the dynamic power grid performance under transient scenarios; an exact elasto-dynamics theory for bending vibrations for a class of flexible structures; motion profile tracking control and vibrating disturbance suppression for quadrotor aerial vehicles using artificial neural networks and particle swarm optimization; and multiple adaptive controllers based on B-Spline artificial neural networks for regulation and attenuation of low frequency oscillations for large-scale power systems. The book is addressed for both academic and industrial researchers and practitioners, as well as for postgraduate and undergraduate engineering students and other experts in a wide variety of disciplines seeking to know more about the advances and trends in mathematical modelling, control and identification of engineering systems in which undesirable oscillations or vibrations could be presented during their operation.
    Keywords: B-spline neural networks ; adaptive power system control ; coordinated multiple controllers ; StatCom ; exact plate theory ; thick plate ; bending vibration ; partial differential operator theory ; gauge condition ; data-driven control ; reactive power compensation ; STATCOM ; voltage control ; voltage source converter ; quadrotor UAV ; artificial neural networks ; robust control ; Taylor series ; B-splines ; particle swarm optimization ; active suspension ; model predictive control ; linear parameter varying ; ellipsoidal set ; attraction sets ; quadratic stability ; algebraic identification ; rotor-bearing system ; finite element model ; rotordynamic coefficients ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
    Language: English
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This Reprint Book provides recent studies addressing encapsulation systems for active compounds (e.g., drugs and food ingredients) to improve the quality of life around the world. The content may be helpful for the colleagues and students working on encapsulation of active compounds.
    Keywords: carboxymethyl chitosan ; mangosteen ; deodorant ; skin moisturizing ; trans-2-nonenal ; accelerated stability test ; guava ; carotenoids ; microencapsulation ; mucilage ; spray-drying ; aloe vera ; Opuntia ficus-indica ; ar-turmerone ; polymeric nanoparticles ; anticancer activity ; release study ; biodegradable polymers ; apple fiber ; trehalose ; sucrose ; blackberry phenolics ; blackberry volatiles ; starch ; Bisphenol A ; Moringa leaf extract ; encapsulating Moringa leaf extract ; nanoparticles ; alginate ; chitosan ; Ib-M peptides ; E. coli ; peptide stability ; polyethylene glycol methacrylate ; oregano ; phenolic compounds ; nanoencapsulation ; bioaccessibility ; curcumin ; zebrafish embryogenesis ; oxidative stress ; neuroprotection ; PCL nanoparticles ; paraquat ; grafted microparticles ; sodium hyaluronate ; crosslinked microparticles ; metronidazole adsorption ; adsorption isotherm ; adsorption kinetics ; metronidazole release ; polyelectrolyte ; complex coacervate ; polyamine ; stimulus-responsive materials ; controlled release ; encapsulation ; hybrids ; clay ; sodium alginate ; rosemary essential oil ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
    Language: English
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: This Special Issue highlights fundamental changes to the questions that we can ask about both the recent past and deep time. Delve into the forefront of paleontological research with this Special Issue reprint. Renowned paleontologists from around the world share groundbreaking insights into ancient life on Earth. Discover the latest advances in fossil discovery, analytical techniques, interdisciplinary collaborations, and technological innovations that are shaping our understanding of evolution and the Earth's history. This collection of cutting-edge research is a must-read for scientists, researchers, and enthusiasts interested in the dynamic field of paleontology in the modern era.
    Keywords: REE ; Tyrannosaurus rex ; molecular paleontology ; geochemical taphonomy ; diagenesis ; bone ; protein ; collagen ; Hell Creek Formation ; cuticle ; Eocene ; Fur Formation ; insects ; melanin ; mo-clay ; pigment ; Stolleklint Clay ; structural coloration ; Ølst Formation ; fossil ; dinosaur ; paleoproteomics ; porphyrin ; keratin ; feather ; taphonomy ; degradation ; microbes ; CO2 ; apatite ; paleontology ; China ; history ; 20th century ; 21th century ; paleobiology ; history and philosophy of paleontology ; twenty-first-century paleontology ; paleobiological revolution ; technoscience and global issues ; fossil proteins ; rare earth elements ; soft-tissue preservation ; geochemistry ; soft tissues ; molecular preservation ; Hornerstown Formation ; shallow marine ; glauconite ; hybridization ; introgression ; ancient DNA (aDNA) ; hominin paleontology ; paleoanthropology ; Brachylophosaurus ; Judith River Formation ; ELISA ; RIA ; Venta Micena site ; VM-0 ; VM-1960 ; taxonomy ; morphometrics ; phylogeny ; evolution ; morphological clock ; molecular clock ; biodiversity ; palaeobiogeography ; macroevolution ; primates ; Cercopithecidae ; monkeys ; genotype:phenotype mapping ; dentition ; Equidae ; Equinae ; hipparionini ; protohippini ; equini ; paleoecology ; paleoclimatology ; biochronology ; steroids ; diet ; coprolites ; Gryphaea dilatata ; crystallographic texture ; pole figures ; neutron diffraction ; recrystallization ; thick-walled shells ; molecular taphonomy ; fossils ; preservation ; mass spectrometry ; dinosaurs ; Neanderthal ; Combe-Grenal ; juvenile ; mandible ; periodontitis ; tooth ; tartar ; SEM analysis ; n/a ; terrestrialization ; artrhopods ; Cambrian explosion ; molecular clocks ; palaeontology ; phylogenomics ; teeth ; enamel ; microanalysis ; Purussaurus ; Neoepiblema ; miocene ; ICP-MS ; MEV ; microscopy ; magnetic resonance imaging ; micro-computed tomography ; radiocarbon dating ; DNA barcoding ; synchrotron ; bone remodeling ; elemental analysis ; diagenetic alteration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: This Special Issue introduces recent research results on MEMS packaging and 3D integration whose subjects can be divided as follow; three papers on biocompatible implantable packaging, three papers on interconnect, three papers on bonding technologies, one paper on vacuum packaging, and three papers on modeling and simulation.
    Keywords: heterogeneous integration ; wafer bonding ; wafer sealing ; room-temperature bonding ; Au-Au bonding ; surface activated bonding ; Au film thickness ; surface roughness ; microelectromechanical systems (MEMS) packaging ; inkjet printing ; redistribution layers ; capacitive micromachined ultrasound transducers (CMUT) ; fan-out wafer-level packaging (FOWLP) ; adhesion ; thin film metal ; parylene ; neural probe ; scotch tape test ; FEM ; MEMS resonator ; temperature coefficient ; thermal stress ; millimeter-wave ; redundant TSV ; equivalent circuit model ; S-parameters extraction ; technology evaluation ; MEMS and IC integration ; MCDM ; fuzzy AHP ; fuzzy VIKOR ; fan-out wafer-level package ; finite element ; glass substrate ; reliability life ; packaging-on-packaging ; thermal sensors ; TMOS sensor ; finite difference time domain ; optical and electromagnetics simulations ; finite element analysis ; ultrasonic bonding ; metal direct bonding ; microsystem integration ; biocompatible packaging ; implantable ; reliability ; Finite element method (FEM) ; simulation ; multilayer reactive bonding ; integrated nanostructure-multilayer reactive system ; spontaneous self-ignition ; self-propagating exothermic reaction ; Pd/Al reactive multilayer system ; Ni/Al reactive multilayer system ; low-temperature MEMS packaging ; crack propagation ; microbump ; deflection angle ; stress intensity factor (SIF) ; polymer packaging ; neural interface ; chronic implantation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: The World Health Organization recommends the consumption of plant foods instead of animal-origin foods due to their high levels of saturated fat and cholesterol. Consumption of plant products has led to research on the beneficial properties of their components beyond basic nutrients. Vegetable-derived peptides have shown multifunctional effects related to chronic diseases, attracting interest from the food, nutraceutical, and pharmaceutical industries. This reprint highlights studies on various vegetable extracts, such as chestnut, quinoa, amaranth, buckwheat, and Protium heptaphyllum gum resin, which have demonstrated antimicrobial, anti-inflammatory, and cholesterol-regulating properties. Specific compounds derived from plants, such as methyl p-coumarate and lupin protein hydrolysate, have shown effectiveness in reducing inflammation and anxiety, respectively. A vegetable extract of rosemary has been studied for its potential to treat osteogenesis imperfecta. Moreover, this repprint reviews Lycium barbarum berries, essential oils from Annonaceae species, antioxidant compounds, phytosterols, and natural compounds for the prevention and treatment of oral mucositis was discussed. Overall, these studies suggest that vegetable-derived bioactive compounds could serve as new nutraceuticals to prevent and treat a wide range of chronic diseases.
    Keywords: hypercholesterolemia ; gene expression ; HMGCR ; PCSK9 ; PPARα ; enzymatic activity ; molecular docking ; statin ; monacolin ; breu branco ; seed storage proteins ; peptides ; anti-inflammatory ; antioxidant ; trypsin inhibitors ; quinoa ; amaranth ; buckwheat ; in vitro gastro-intestinal digestion ; natural products ; Brazilian species ; essential oil ; applications ; phytosterols ; neurodegeneration ; Alzheimer’s disease ; blood brain barrier ; obesity ; oxidative stress ; dyslipidemia ; diabetes ; enzyme-assisted extraction ; plant material ; phenolic compounds ; oligosaccharides ; prebiotic ; nanocellulose ; nanofibers ; fermentation ; sustainability ; cancer ; drug delivery ; oral mucositis ; treatment ; lupin ; protein hydrolysates ; anxiety ; ApoE−/− ; functional foods ; peptidomics ; rosemary extract ; collagen type I ; unfolded protein response ; autophagy ; proteasome ; skin fibroblasts ; apoptosis ; osteogenesis imperfecta ; asthma ; methyl p-coumarate ; Th2 cytokines ; eosinophil ; NF-κB ; Castanea sativa shells ; Subcritical Water Extraction (SWE) ; antimicrobial activity ; goji berries ; pro-healthy effects ; phenolics ; biological properties ; functional ingredients ; in vitro cultures ; Ruta montana ; coumarins ; alkaloids ; antibiofilm formation ; antibacterial activity ; antioxidant activity ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Keywords: QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 10
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Nondestructive testing and evaluation (NDT&E) is one of the most important techniques for determining the quality and safety of materials, components, devices, and structures. NDT&E technologies include ultrasonic testing (UT), magnetic particle testing (MT), magnetic flux leakage testing (MFLT), eddy current testing (ECT), radiation testing (RT), penetrant testing (PT), and visual testing (VT), and these are widely used throughout the modern industry. However, some NDT processes, such as those for cleaning specimens and removing paint, cause environmental pollution and must only be considered in limited environments (time, space, and sensor selection). Thus, NDT&E is classified as a typical 3D (dirty, dangerous, and difficult) job. In addition, NDT operators judge the presence of damage based on experience and subjective judgment, so in some cases, a flaw may not be detected during the test. Therefore, to obtain clearer test results, a means for the operator to determine flaws more easily should be provided. In addition, the test results should be organized systemically in order to identify the cause of the abnormality in the test specimen and to identify the progress of the damage quantitatively.
    Keywords: composites ; multi-scale ; embedded damage ; non-destructive testing ; photoacoustic ; ultrasonic representation ; terahertz ; coded-aperture imaging ; convolution neural network (CNN) ; fast image reconstruction ; nondestructive evaluation ; acoustic nonlinearity parameter ; indirect method ; laser ultrasound ; fully non-contact ; surface acoustic wave ; UWB-PPM ; UWB-OOK ; buried objects ; nondestructive environment ; Levenberg–Marquardt method ; textured surface anomaly detection ; computer vision ; deep learning ; attention mechanism ; adaptive fusion ; power quality disturbances ; long short term memory ; convolutional neural network ; short time Fourier transform ; leaky Lamb wave ; semi-analytical finite element (SAFE) ; waveguide sensor ; finite-width plate ; waveguide plate ; width modes ; spatial beating ; Rayleigh–Sommerfeld integral (RSI) ; weld cracks ; eddy current nondestructive testing ; gradiently relative magnetic permeability ; heat affected zone ; austenitic stainless steel ; circulating fluidized bed combustion boiler ; water-cooled wall tube ; magnetic sensor array ; magnetic flux density ; flexible ultrasonic probe ; neutron irradiation embrittlement ; reactor pressure vessel ; magnetic nondestructive evaluation ; micromagnetic multiparameter microstructure and stress analysis 3MA ; magnetic adaptive testing ; 3D imaging of metal grains ; non-destructive testing methods ; stacking images ; SA106 carbon steel ; terahertz waves ; refractive index ; thickness measurement ; Shim stock films ; composite materials ; reflection mode ; neutron radiography ; Bragg-edge imaging ; gas tungsten arc welding (GTAW) ; low transformation temperature (LTT) steel ; austenite-to-martensite transformation ; Debye–Waller factor ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: This reprint focuses on both advanced metals and their alloys and the areas of physical and process metallurgy, materials science, and processing techniques. Specific areas of interest also include titanium/nickel-based superalloys, intermetallics, advanced metallic materials, nanomaterials, metal matrix composites, functional materials, related synthesis and processing techniques, finite element modelling, statistical analysis, physical/mechanical property characterization, experimental validation, and other relevant phenomena. Physical metallurgy is important in the design and optimization of advanced materials with superior physical and mechanical properties through microstructural modifications and processing techniques. The goal of reprint was to bring together recent progress, novel technologies, and advanced equipment for the design and development of advanced metals and alloys and provide guidelines/benchmarks for further research in related areas. Composites, intermetallics, and nanomaterials as well as functional materials will be also included. Some of the recent advances in the field of advanced metals and alloys include novel material processing techniques, manufacturing methods and theories, microstructural characterization, modelling development, and advanced equipment. Conventional and nonconventional processes related to machining, forming, laser processing, additive/subtractive manufacturing, surface modification, and the solidification of high-performance alloys/metals are also included.
    Keywords: Fe-rich Al–Si alloy ; β-Al5FeSi phase ; cooling rate ; melt spinning ; microstructure ; strengthening mechanisms ; Zn-Mg-Ti alloy ; biodegradable metals ; mechanical properties ; cytotoxicity ; Fe-B-W alloy ; manganese ; aluminum ; molten zinc ; microanalysis ; corrosion ; hydrogenated–dehydrogenated titanium powder ; laser directed energy deposition ; mechanical property ; radio frequency plasma technique ; high entropy alloy ; bulk metallic glass ; similar element substitution/addition ; glass forming ability ; lattice distortion ; sapphire ; surface metallization ; deposition mechanism ; wettability ; low-temperature joining ; silver alloy bonding wire ; bonding strength ; vulcanization resistance ; cathodic passivation ; Mg–Nd alloy ; precipitate ; eutectic growth ; modelling and simulation ; recrystallization ; microstructure-property characterization simulation and modeling ; heat treatment and surface treatment ; TC4 alloy ; EBCHM ; aging treatment ; glass-forming ability ; corrosion behavior ; amorphous alloy ; phase transformation ; mechanical behavior ; corrosion wear resistance ; gear grinding ; white layer ; grinding temperature ; surface integrity ; AlSi10Mg alloy ; friction stir processing ; grain boundary ; texture ; dynamic recrystallization ; silver wire ; wire bonding ; chloride ions ; ion migration ; galvanic corrosion ; Cu-15Ni-8Sn alloys ; grain size ; solution treatment ; microalloying ; microstructural evolution ; laser-powder bed fusion ; MgAl2O4 ; TiB2 ; metallothermic reduction ; SHS powder metallurgy ; combustion wave propagation ; HSLA steel ; microstructural characterization ; laser welding ; thick plate ; corrosion resistance ; high entropy alloys ; lightweight ; magnesium alloys ; ultrasound treatment ; solution ; aging ; Mg17Al12 ; converter ; vortex ; flow field analysis ; numerical simulation ; steel ball ; skew rolling ; cold forming ; stainless steel ; copper–scandium CuSc ; copper alloy ; differential scanning calorimetry DSC ; precipitation kinetics ; cold-working ; cold-rolling ; activation energy ; Kissinger method ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-03-21
    Description: This book captures advancements in the applications of computational intelligence (artificial intelligence, machine learning, etc.) to problems in the mineral and mining industries. The papers present the state of the art in four broad categories: mine operations, mine planning, mine safety, and advances in the sciences, primarily in image processing applications. Authors in the book include both researchers and industry practitioners.
    Keywords: truck dispatching ; mining equipment uncertainties ; orebody uncertainty ; discrete event simulation ; Q-learning ; grinding circuits ; minerals processing ; random forest ; decision trees ; machine learning ; knowledge discovery ; variable importance ; mineral prospectivity mapping ; random forest algorithm ; epithermal gold ; unstructured data ; blast impact ; empirical model ; mining ; fragmentation ; mine worker fatigue ; random forest model ; health and safety management ; stockpiles ; operational data ; mine-to-mill ; geostatistics ; ore control ; mine optimization ; digital twin ; modes of operation ; geological uncertainty ; multivariate statistics ; partial least squares regression ; oil sands ; bitumen extraction ; bitumen processability ; mine safety and health ; accidents ; narratives ; natural language processing ; random forest classification ; hyperspectral imaging ; multispectral imaging ; dimensionality reduction ; neighbourhood component analysis ; artificial intelligence ; mining exploitation ; masonry buildings ; damage risk analysis ; Bayesian network ; Naive Bayes ; Bayesian Network Structure Learning (BNSL) ; rock type ; mining geology ; bluetooth beacon ; classification and regression tree ; gaussian naïve bayes ; k-nearest neighbors ; support vector machine ; transport route ; transport time ; underground mine ; tactical geometallurgy ; data analytics in mining ; ball mill throughput ; measurement while drilling ; non-additivity ; coal ; petrographic analysis ; macerals ; image analysis ; semantic segmentation ; convolutional neural networks ; point cloud scaling ; fragmentation size analysis ; structure from motion ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 13
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-07-06
    Description: It is our pleasure to present this Special Issue of Molecules entitled “Food Processing and Its Impact on Phenolic and other Bioactive Constituents in Food”. Bioactive compounds including phenolic ingredients have long been used as important constituents of a healthy diet. As a result, consumer awareness about the important role of high-quality products rich in bioactive compounds—especially phenolic compounds—in human nutrition, health, and prevention against diseases has increased. Additionally, methods for food processing, regardless of the technology used, have a huge impact on the quality of the final products. Therefore, the big challenges for scientists lie in the monitoring of changes during food processing and the optimization of technology to achieve the minimal degradation of nutrients (including phenolic compounds). Thus, for this Special Issue, I encourage you to read some interesting papers aimed at bringing the latest scientific news, insights, and advances in the field of food processing and its impact on bioactive constituents in food, especially phenolic compounds. The information presented will certainly arouse considerable interest among a large group of our readers from different disciplines and research fields.
    Keywords: apple ; phenolic compounds ; genetic resources ; HPLC-DAD ; thyme ; oregano ; dry herbs ; polyphenols ; chlorophyll ; carotenoids ; microbial ; cytotoxicity ; dissolution test ; functional food ; innovative food ; drying ; natural food ; Helianthus tuberosus ; pro-healthy properties ; plant polyphenols ; food processing ; phenolic content ; bioavailability ; bioaccessibility ; coffee Arabica ; roasting process ; brewing methods ; antioxidant activity ; flavonoids ; caffeine ; pH of infusions ; tannins ; snack ; baking ; carotenoids content ; chlorophyll content ; total polyphenols content ; calorific value ; sensory properties ; sourdough fermentation ; inoculation ; lactic acid bacteria ; FODMAP ; fructans ; antioxidants ; chocolate ; free radical scavenging activity ; reducing power ; functionalization of food ; electronic nose analysis ; isoflavone conversion ; thermal process ; immature seeds ; mature seeds ; internal water content ; konjac ; linseed flour ; fat substitute ; volatile compounds ; lipid oxidation ; encapsulation ; Mauritia flexuosa (aguaje) ; controlled dehydration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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  • 14
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: The eradication of vector-borne diseases is threatened by the limited range of available insecticides, leading, inevitably, to the development of resistance. This is particularly concerning for malaria control, which relies heavily on insecticide-treated nets (ITNs) and indoor residual sprays (IRS). New chemistries are being developed, and innovative deployment of insecticides may play a role in overcoming resistance, either through new types of tools or new means of distribution. A variety of novel product types and vector control strategies are under development and evaluation, which is to be celebrated, but a strong evidence base is needed to guide effective operational deployment decisions. Novel approaches should be supported by robust data collected using appropriate and validated methods to monitor efficacy, durability, and any emerging resistance. This reprint presents original research into developing and characterizing new vector control products, as well as understanding and monitoring insecticide resistance. Review articles explore the impact of insecticide resistance and offer guidance on insecticide choice in the face of pyrethroid resistance. Consensus methodologies are presented, in the form of standard operating procedures (SOPs) designed to be adopted and used to generate reproducible data that can be compared and interpreted across and between studies. It is hoped that this collection of articles offers inspiration and guidance on how consistent data can be generated to inform more effective development, evaluation, and use of new and existing vector control tools.
    Keywords: prallethrin ; insecticide ; spatial treatment ; mosquito fitness ; protection ; pyrethroids ; Aedes albopictus ; Culex pipiens ; life tables ; mosquito ; bite-proof garment ; model ; textile ; non-insecticidal ; physical barrier ; insecticide selection ; out-crossing ; strain authentication ; laboratory screening ; pyrethroid ; pyrethroid resistance ; insecticide resistance ; insecticide resistance management ; vector control ; malaria ; malaria control ; Anopheles ; host-seeking behavior ; insecticide exposure ; pathogen transmission ; Aedes aegypti ; Anopheles gambiae ; ATSB ; Culex quinquefasciatus ; Iroquois ; RNAi ; Saccharomyces cerevisiae ; yeast ; Anopheles mosquito ; fertility ; ovary development ; pyriproxyfen (PPF) ; side-effects ; machine learning ; image classification ; automated identification ; convolutional neural network ; insecticide-treated net (ITN) ; PBO ITN ; synergist ITN ; dual-AI ITN ; insecticide resistance management (IRM) ; method validation ; durability monitoring ; bioinsecticide ; disease transmission ; insecticide-resistance ; mosquito-borne disease ; mosquito control ; natural compounds ; phytochemical ; malaria vector ; insecticide treated nets ; cytochrome P450s ; kdr ; cuticular resistance ; deltamethrin ; imidacloprid ; bifenthrin ; β-cyfluthrin ; etofenprox ; α-cypermethrin ; λ-cyhalothrin ; thiacloprid ; mosquitoes ; Attractive Toxic Sugar Bait (ATSB) ; Attractive Targeted Sugar Bait (ATSB) ; diagnostic bioassay ; resistance monitoring ; insecticide-treated nets (ITN) ; strain characterisation ; method development ; product evaluation ; quality control (QC) ; dual active ingredients (dual-AI) ; bioefficacy ; IRS ; application technology ; broflanilide ; clothianidin ; pirimiphos-methyl ; WHO tube ; WHO tunnel test ; ITNs ; interceptor ; interceptor G2 ; membrane ; human arm ; rabbit ; bioassay ; bio-efficacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-07-06
    Description: Connected intelligent sensing reshapes our society by empowering people with increasing new ways of mutual interactions. As integration technologies keep their scaling roadmap, the horizon of sensory applications is rapidly widening, thanks to myriad light-weight low-power or, in same cases even self-powered, smart devices with high-connectivity capabilities. CMOS integrated circuits technology is the best candidate to supply the required smartness and to pioneer these emerging sensory systems. As a result, new challenges are arising around the design of these integrated circuits and systems for sensory applications in terms of low-power edge computing, power management strategies, low-range wireless communications, integration with sensing devices. In this Special Issue recent advances in application-specific integrated circuits (ASIC) and systems for smart sensory applications in the following five emerging topics: (I) dedicated short-range communications transceivers; (II) digital smart sensors, (III) implantable neural interfaces, (IV) Power Management Strategies in wireless sensor nodes and (V) neuromorphic hardware.
    Keywords: wake-up receiver ; digital controller ; reliability ; electronic toll collection (ETC) system ; dedicated short range communication (DSRC) ; temperature compensation ; piezoresistive ; pressure sensor ; negative temperature coefficient ; ACE-Q100 ; CMOS ; epilepsy ; seizure ; multichannel neural recording ; feature extraction ; closed-loop neurostimulator ; low-power ; low-noise amplifier ; implantable medical device ; switched capacitor ; voltage converter ; wide load range ; multiphase operation ; variable frequency ; integrated circuits ; EEPROM reprogrammable fuses ; memory cells ; trimming techniques with fuses ; digital temperature sensor ; temperature sensor with digital serial interface ; asynchronous control logic ; successive approximation register (SAR) ; wireless access in vehicular environments (WAVE) ; low power consumption ; capacitive digital to analog converter (CDAC) ; CMOS neural amplifier ; AC coupling ; pseudoresistor ; nonlinear distortion ; area-efficient design ; sensor node ; power mode ; wireless sensor networks ; power management ; spiking neural network ; leaky integrate and fire ; neuromorphic ; artificial neural networks ; artificial intelligence ; image classification ; capacitance-to-digital converter ; iterative-delay-chain discharge ; CMOS capacitive sensor interface ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 16
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Phenolic compounds in food such as fruits, vegetables, wine, spices, and oils have been characterized and their possible effects on human health has been studied in depth. Several technological aspects have also been considered concerning the sustainable extraction of phenolic compounds, the long-term storage effects, and the influence of fermentation and boiling techniques on their properties.
    Keywords: chestnut ; water curing ; non-targeted MS analysis ; antioxidants ; Arecaceae ; polyphenols ; volatile content ; antioxidant activity ; liquid chromatography ; inflammation ; lung ; oxidative damage ; antiviral ; polyphenol ; phenolic acids ; flavonoids ; Vicia faba ; functional food ; green solvents ; biologically active compounds ; selective separation ; medicinal plants ; ultrasonic-assisted extraction ; microwave-assisted extraction ; kombucha ; black tea ; long-term storage ; antioxidant scavenging activity ; total phenolic content ; meat quality ; antimicrobial activity ; C. scolymus ; food quality ; beverages ; health properties ; antioxidant activities ; fibrinogen ; albumin ; rutin ; tannic acid ; resveratrol ; binding properties ; first order ; kinetic modelling ; zero order ; food processing ; herbal tea ; boiling ; EVOO ; vegetables ; phenolic compounds ; thermal treatment ; processing techniques ; bioaccessibility ; bioavailability ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-07-06
    Description: The articles in this Special Issue cover a very wide range of topics related to the cultivation, management and use of fast-growing tree species. In addition to research on breeding and on the influence of pruning practices on the height growth of paulownia, three articles deal with the influence of site characteristics and nutrient availability on the physiology and yield security of fast-growing tree species. Another article focuses on the modeling of soil carbon in Salix plantations, while the article by Boruszewski et al. reports on potentially suitable areas for the planting of fast-growing tree species in Poland. Zitzmann and Rode examine the impact of short-rotation plantation management on phytodiversity, while Helbig et al. deal with the influence of leaf feeding on the growth of poplars and willows. Finally, Hernandez-Estrada et al. describe the dry matter loss of poplar wood chips during storage.
    Keywords: woody biomass crops ; bioenergy ; biodiversity ; species richness ; flora ; vascular plants ; short rotation coppices ; poplars ; willows ; feeding simulation ; defoliation ; herbivory ; short rotation coppice ; phosphatase activity ; nutrient content ; growth stages ; biomass ; willow ; Salix ; capacity ; European larch ; fast-growing trees ; plantations ; plantation area ; poplar cultivar “Hybrid 275” ; sown area ; biomass production ; life cycle assessment ; climate impact ; soil organic carbon ; genotypic difference ; CRISPR/Cas9 ; genome editing ; Populus ; INRA 717-1B4 ; pyramidal plant habitus ; leaf petiole angle ; branch angle ; nitrogen ; phosphorus ; carbon ; physiology ; F. mandshurica ; Robinia pseudoacacia L. ; photosynthetic vitality ; chlorophyll and phenol content ; nutrition supply ; dry matter yield ; land reclamation ; spring pruning ; year-long pruning ; branching ; angle diversion of sprout ; dry matter losses ; poplar wood chips ; laboratory scale ; cultivable saproxylic microbiota ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Today, the flow of electricity is bidirectional, and not all electricity is centrally produced in large power plants. With the growing emergence of prosumers and microgrids, the amount of electricity produced by sources other than large, traditional power plants is ever-increasing. These alternative sources include photovoltaic (PV), wind turbine (WT), geothermal, and biomass renewable generation plants. Some renewable energy resources (solar PV and wind turbine generation) are highly dependent on natural processes and parameters (wind speed, wind direction, temperature, solar irradiation, humidity, etc.). Thus, the outputs are so stochastic in nature. New data-science-inspired real-time solutions are needed in order to co-develop digital twins of large intermittent renewable plants whose services can be globally delivered.
    Keywords: self-healing grid ; machine-learning ; feature extraction ; event detection ; optimization techniques ; manta ray foraging optimization algorithm ; multi-objective function ; radial networks ; optimal power flow ; automatic P2P energy trading ; Markov decision process ; deep reinforcement learning ; deep Q-network ; long short-term delayed reward ; inter-area oscillations ; modal analysis ; reduced order modeling ; dynamic mode decomposition ; machine learning ; artificial neural networks ; steady-state security assessment ; situation awareness ; cellular computational networks ; load flow prediction ; contingency ; fuzzy system ; change detection ; data analytics ; data mining ; filtering ; optimization ; power quality ; signal processing ; total variation smoothing ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: This book presents the advances in plant salinity stress and tolerance, including mechanistic insights revealed using powerful molecular tools and multi-omics and gene functions studied by genetic engineering and advanced biotechnological methods. Additionally, the use of plant growth-promoting rhizobacteria in the improvement of plant salinity tolerance and the underlying mechanisms and progress in breeding for salinity-tolerant rice are comprehensively discussed. Clearly, the published data have contributed to the significant progress in expanding our knowledge in the field of plant salinity stress and the results are valuable in developing salinity-stress-tolerant crops; in benefiting their quality and productivity; and eventually, in supporting the sustainability of the world food supply.
    Keywords: watermelon ; salt stress ; RNA-seq ; amino acids ; endocytosis ; Arabidopsis thaliana ; halophyte ; high-affinity potassium transporter (HKT) ; Na+ transporter ; salt tolerance ; Sporobolus virginicus ; aquaporins ; barley ; ion transport ; oocytes ; plasma membrane intrinsic proteins (PIPs) ; GmbZIP15 ; transcription factor ; drought stress ; soybean ; biotechnology breeding ; high-throughput sequencing ; QTLs ; rice ; halophytic wild barley ; salinity ; osmotic stress ; metabolome ; transcriptome ; ionome ; stress adaptation ; Hordeum marinum ; aquaporin ; Zygophyllum xanthoxylum ; plant growth ; abiotic stress ; sensing ; signaling ; transcription factors ; osmoregulation ; antioxidation ; ion homeostasis ; jasmonates ; jasmonate signaling pathway ; crosstalk ; exogenous jasmonate applications ; GWAS ; PGPR ; ACC deaminase ; seed priming ; IAA ; cell wall integrity ; cell wall sensor ; LRXs ; CrRLK1Ls ; Millettia pinnata ; calmodulin-like ; heterologous expression ; halophiles ; plant growth-promoting rhizobacteria (PGPR) ; RNA sequence analysis (RNA-seq) ; quantitative reverse transcriptase PCR (qRT-PCR) ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: In recent years, new and emerging digital technologies applied to food science have been gaining attention and increased interest from researchers and the food/beverage industries. In particular, those digital technologies that can be used throughout the food value chain are accurate, easy to implement, affordable, and user-friendly. Hence, this Special Issue (SI) is dedicated to novel technology based on sensor technology and machine/deep learning modeling strategies to implement artificial intelligence (AI) into food and beverage production and for consumer assessment. This SI published quality papers from researchers in Australia, New Zealand, the United States, Spain, and Mexico, including food and beverage products, such as grapes and wine, chocolate, honey, whiskey, avocado pulp, and a variety of other food products.
    Keywords: sensory ; physicochemical measurements ; artificial neural networks ; near infra-red spectroscopy ; wine quality ; machine learning modeling ; weather ; consumer acceptance prediction ; data fusion ; emotion recognition ; facial expression recognition ; galvanic skin response ; machine learning ; neural networks ; sensory analysis ; avocado ; cultivars ; preference mapping ; sensory evaluation ; sensory descriptive analysis ; consumer science ; unifloral honeys ; botanical origin ; physicochemical parameters ; classification ; natural language processing ; deep learning ; sensory science ; flavor lexicon ; long short-term memory ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-12-06
    Description: The second volume of the book contains the manuscripts that were accepted for publication in the MDPI Special Topic "Cyber Security and Critical Infrastructure" after a rigorous peer-review process. Authors from academia, government and industry contributed their innovative solutions, consistent with the interdisciplinary nature of cybersecurity. The book contains 16 articles, including an editorial that explains the current challenges, innovative solutions and real-world experiences that include critical infrastructure and 15 original papers that present state-of-the-art innovative solutions to attacks on critical systems.
    Keywords: Cybersecurity ; critical Infrastructures ; privacy preservation ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Recombinant viruses expressing reporter fluorescent or bioluminescent proteins are an excellent option to evaluate the dynamics of viral infection progression in both cultured cells and/or validated animal models of viral infection. Reporter proteins are valid surrogates for direct detection of infected cells in vitro and in vivo, without the use of secondary methodologies to identify infected cells. By eliminating the need of secondary labeling, tractable replicating-competent, reporter-expressing viruses provide an ideal approach to monitor viral infections in real time, representing a significant advance in the study of the biology of viruses, to evaluate vaccination approaches, and to identify new therapeutics against viral infections using high-throughput screening settings. In this Special Issue “Replication-Competent Reporter-Expressing Viruses” we review replication-competent, reporter-expressing viruses belonging to different families, methods of characterization, and applications to facilitate the study of in vitro and in vivo viral infections. We also seek to discuss disadvantages and limitations associated with these reporter-expressing viruses. Finally, we provide rational future perspectives and additional avenues for the development, characterization, and applications of recombinant, reporter-expressing, competent viruses.
    Keywords: QH301-705.5 ; luminescence ; virus rescue approaches ; fluorescence ; Recombinant viruses ; plasmid-based reverse genetics ; reporter genes ; replicating-competent reporter-expressing viruses ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 23
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Introducing “A Feasible Approach for Natural Products to Treatment of Diseases”–an exploration of the therapeutic potential locked within nature’s abundant offerings. This comprehensive reprint delves into the fascinating realm of natural products, uncovering their inherent properties, mechanisms of action, and potential roles in effective disease management. Through extensive scientific research and reviews, the authors shed light on the immense potential of natural products as a viable approach to enhancing health and combating diseases. This reprint presents a diverse and multidimensional exploration, bridging the gap between traditional wisdom and contemporary scientific understanding and offering new avenues for healthcare professionals, researchers, and enthusiasts to harness the power of nature’s remarkable resources. As a catalyst for unlocking the healing potential of natural products, this reprint inspires further investigation and innovation, and drives us towards a future where their integration into mainstream healthcare becomes indispensable. Discover the possibilities and embark on a health and well-being journey with “A Feasible Approach for Natural Products to Treatment of Diseases”.
    Keywords: cancer immunotherapy ; fructan ; FT-IR ; mass spectrometry ; young green barley ; COVID-19 ; β-glucans ; immunomodulation ; anti-inflammation ; anti-oxidant ; ACE2 regulation ; impedance ; ECIS ; antitumor activity ; anticancer properties ; betulin ; betulinic acid ; Amadori rearrangement compounds ; barley ; anti-obesity ; arginyl-fructose ; adipogenic ; ergosta-5,7,22,24(28)-tetraenol (ERGT) ; cholesta-5,7,22,24-tetraenol (CHT) ; ergosterol biosynthesis ; antimetabolite ; suicide substrate ; Trypanosoma brucei ; coronavirus SARS-CoV-2 ; main protease ; Saussurea costus ; molecular docking ; GC-MS profiling ; Molineria recurvata ; diabetic nephropathy ; urinary biomarkers ; inflammation ; oxidative stress ; walnut ; Juglans regia ; high-fat diet ; insulin resistance ; cognitive function ; JNK/NFκB pathway ; Citri Reticulatae Pericarpium ; flavonoids ; anticancer ; mechanism ; phenotype ; Angelica sinensis polysaccharide ; Astragalus membranaceus polysaccharide ; hexokinase 2 ; glycolysis ; JAK2/STAT3 pathway ; liver regeneration ; Holoptelea integrifolia ; MMP-9 ; wound healing ; friedelin ; oxalactam A ; macrolactam ; anti-Rhizoctonia solani ; Penicillium oxalicum ; molecular dynamics ; non-alcoholic fatty liver disease (NAFLD) ; natural products ; terpenoids ; mechanisms ; treatment ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-10-25
    Description: The recent successes of machine learning, especially regarding systems based on deep neural networks, have encouraged further research activities and raised a new set of challenges in understanding and designing complex machine learning algorithms. New applications require learning algorithms to be distributed, have transferable learning results, use computation resources efficiently, convergence quickly on online settings, have performance guarantees, satisfy fairness or privacy constraints, incorporate domain knowledge on model structures, etc. A new wave of developments in statistical learning theory and information theory has set out to address these challenges. This Special Issue, "Machine Learning and Information Theory", aims to collect recent results in this direction reflecting a diverse spectrum of visions and efforts to extend conventional theories and develop analysis tools for these complex machine learning systems.
    Keywords: supervised classification ; independent and non-identically distributed features ; analytical error probability ; empirical risk ; generalization error ; K-means clustering ; model compression ; population risk ; rate distortion theory ; vector quantization ; overfitting ; information criteria ; entropy ; model-based clustering ; merging mixture components ; component overlap ; interpretability ; time series prediction ; finite state machines ; hidden Markov models ; recurrent neural networks ; reservoir computers ; long short-term memory ; deep neural network ; information theory ; local information geometry ; feature extraction ; spiking neural network ; meta-learning ; information theoretic learning ; minimum error entropy ; artificial general intelligence ; closed-loop transcription ; linear discriminative representation ; rate reduction ; minimax game ; fairness ; HGR maximal correlation ; independence criterion ; separation criterion ; pattern dictionary ; atypicality ; Lempel–Ziv algorithm ; lossless compression ; anomaly detection ; information-theoretic bounds ; distribution and federated learning ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Several epidemiological studies have demonstrated that oxidative stress is associated with a number of health disorders, including cardiovascular malfunction, certain types of cancer, diabetes mellitus, many other auto-immune diseases, and even ageing. The body possesses multiple mechanisms to counteract oxidative stress, which employ antioxidant compounds that are either naturally generated in situ (endogenous antioxidants) or externally supplied through food (exogenous antioxidants). These antioxidants are able to counteract oxidative stress, thanks to their ability to neutralize excess free radicals and protect the cellular lipids, proteins, and DNA from molecular damage. Exogenous antioxidants from the diet are of increasing interest because of their beneficial role in maintaining good health and in preventing chronic diseases. Indeed, a diet rich in dietary antioxidants, especially from fruits and vegetables, has been correlated with a successful prevention and lower incidence of several degenerative pathologies, including obesity, diabetes, cardiovascular diseases, and cancer. This Special Issue of Nutrients welcomes the submission of manuscripts, either describing original research or reviewing scientific literature, examining the role of diets rich in antioxidant compounds in the prevention of chronic diseases and the characteristics of the antioxidants included in such diets.
    Keywords: QH301-705.5 ; antioxidants ; chronic diseases ; dietary supplementation ; human health ; prevention ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: Information is key, which means that measurements are key. For this reason, this book provides unique insight into state-of-the-art research works regarding optical measurement systems. Optical systems are fast and precise, and the ongoing challenge is to enable optical principles for in-process measurements. Presented within this book is a selection of promising optical measurement approaches for real-world applications.
    Keywords: speckle photography ; in-process measurement ; deep rolling process ; generalized phase shifting interferometry ; dual-aperture common-path interferometer ; real-time optical instrumentation ; optomechatronic systems ; electrical steel ; optical coherence tomography ; OCT ; scanning ; process monitoring ; laser material processing ; spot compensation ; low coherence interferometry ; LCI ; wind lidar ; Doppler lidar ; bistatic ; metrology ; traceability ; wind energy ; meteorology ; diffraction grating ; grating pitch ; mode-locked femtosecond laser ; laser diffraction ; diffraction equation ; measurement uncertainty analysis ; image processing ; pattern recognition ; wind energy turbines ; turbulence wedges ; coherence scanning interferometry ; in-process application ; Mirau interferometer ; vibration compensation ; interferometric distance sensor ; optical path length modulation ; oscillating reference mirror ; hairpin ; laser welding ; semantic segmentation ; dilated convolution ; sdu-net ; spatter detection ; quality assurance ; fast prediction time ; in situ measurement ; optical metrology ; quality control ; interferometry ; fringe projection ; computational shear interferometry ; coherence function ; structure function ; additive manufacturing ; medium voltage switchgear ; SF6 alternatives ; UV-Vis spectroscopy ; gas mixing modeling ; multicomponent diffusion analysis ; explosion ; coal dust ; methane ; explosion suppression ; spectral characteristics ; explosion pressure ; radiation intensity ; free radicals ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 27
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Diet and nutrition are key tools in promoting health and reducing the comorbidities of chronic diseases. There are thousands of biomolecules in fruits, vegetables, wild and medicinal plants, other land and marine organisms, which can exert functional and health-promoting effects through bioactivity beyond nutrition. From the enormous amount of knowledge generated from different natural bioactive ingredients present in foods, we are aiming to bring together experts working in different fields of food, nutrition, and health, in order to work on this Special Issue, with a comprehensive collection of papers to gain insight into the most promising bioactive compounds in different foods, to improve the preservation of bioactivity during the food processing chain, and to provide scientific evidence of the efficacy of key bioactives in foods in preventing disease and improving health and wellbeing.
    Keywords: QH301-705.5 ; TX341-641 ; Health ; Bioactives ; Nutrition and Metabolism ; Nutrients ; Bioavailability ; Food ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Processing and Conversion of Oil and Gas: Modeling, Control, Simulation, and Optimization describes the core of the activity of petrochemical engineers, process controller engineers, industrial engineers, energy engineers, and researchers in the oil and gas field. This reprint explores the modeling, control, simulation, and optimization of new and revamped petrochemical processes using proven software. Thus, it offers novel illustrative examples, prospective applications, and solutions to improve these processes. This reprint aims to combine theoretical principles with examples modeled by commonly used simulation software employing steady-state or dynamic process simulation. Furthermore, applying numerical methods and optimization at both the theoretical and practical levels is within the scope of this reprint.
    Keywords: jet stability ; swirl ; twist ; dominant mode ; Brassica Napus ; fatty acid methyl esters ; 2-Ethyl-2-hydroxymethyl-1,3-propanediol ; viscosity ; batch reactor ; kinetics ; self-excited oscillation pulse jet ; nozzle ; large eddy simulation ; peak velocity ; cavitation number ; coal tar ; wash oil ; nitrogen-containing compounds ; indole ; formamide equilibrium extraction ; price bubbles ; bubble length ; petroleum products ; GSADF ; Pakistan ; pipeline safety ; risk classification ; pipeline failure ; fuzzy analytic hierarchy process ; pipeline risk assessment ; shale gas pipelines ; pressure gradient ; gas–liquid two-phase flow ; flow patterns ; Generalized Additive Model ; dimensionless numbers ; discrete element method ; optimal design ; simulation analysis ; anti-corrosion pill particles ; butyl acetate ; acetic acid ; n-butanol ; esterification ; membrane reactor ; reactive distillation ; amberlyst-15 catalyst ; energy efficiency ; economic evaluation ; methyl isobutyl ketone (MIBK) ; acetone self-condensation ; selective hydrogenation ; process development ; heat integration ; economic analysis ; nano-Pd/nano-ZnCr2O4 catalyst ; dimethyl carbonate ; dimethyl oxalate ; oxidative carbonylation ; azeotropic distillation ; profitability analysis ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-12-06
    Description: Vegetable crops provide valuable minerals and vitamins that are indispensible for human health. Scientists have been working on the genetics of vegetable crops, deciphering the molecular bases of agronomically important traits. These genetic bases and variations in vegetable traits will greatly facilitate vegetable genetic improvement. Therefore, the genes of and genetic research on vegetable crops are of great importance. This Special Issue is a collection of 13 important research papers addressing the genes, genetics, and breeding of major vegetable crops. In the present book, the authors described the genes and QTLs responsible for stress tolerance, disease resistance, vegetable yield, and quality. The 13 research papers cover germplasm enhancement and evaluation, QTL mapping, gene isolation, marker development, and gene expression as well as gene editing in a wide range of vegetable species, including broccoli, pepper, eggplant, onion, and Cucurbita species. Readers from all over the globe are expected to greatly benefit from this Special Issue collection regarding their own work and the goal of improving breeding efficiency with molecular breeding to generate environment-adaptive, high-yield, and high-quality vegetable crops with which to feed the global population of 9.7 billion in an extreme climate by 2050.
    Keywords: pepper ; Capsicum annuum ; Phytophthora capsici ; high-density genetic map ; QTL ; Capcicum annuum L. ; RNA-Seq ; nitrogen-use efficiency ; low-nitrogen tolerance ; CaHSP18.1a ; gene silencing ; transgenic Arabidopsis ; heat stress ; gene expression ; pumpkin ; simple sequence repeat (SSR) ; syntenic relationship ; cross-species markers ; population structure ; eggplant ; heat shock factor (Hsf) ; heat shock protein (Hsp) ; thermotolerance ; C. frutescens ; SSR ; germplasm ; genetic diversity ; CRISPR/Cas ; gene knockout ; genome editing ; germplasm resource ; precision editing ; regulatory framework ; trait improvement ; Brassica oleracea ; broccoli ; candidate gene ; anthocyanin ; allelochemicals ; VOCs properties ; VOCs action ; VOCs detection ; green agriculture ; progress ; genetic researches ; molecular breeding ; transcriptomics ; transcription factor ; heritability ; genetic advance ; multi-trait selection ; principal component analysis ; HRM ; molecular marker ; phylogenetic analysis ; RNA sequencing ; SCAR ; SNP ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The Special Issue “Demand Response in Smart Grids” includes 11 papers on a variety of topics. The success of this Special Issue demonstrates the relevance of demand response programs and events in the operation of power and energy systems at both the distribution level and at the wide power system level. This reprint addresses the design, implementation, and operation of demand response programs, with focus on methods and techniques to achieve an optimized operation as well as on the electricity consumer.
    Keywords: demand response ; population evolution ; irrational behavior ; Markov state ; non-cooperative game ; solid electric thermal storage ; cyber–physical model ; K-means ; support vector machine ; neural network ; data analysis ; demand response (DR), load profile clustering ; k-means ; targeting of customer ; aggregator ; ramp period ; real-time simulation ; multi-objective optimization ; social welfare metrics ; energy allocation ; load disaggregation ; percentage total harmonic distortion and non-intrusive identification of load pattern ; charging strategy ; optimization ; electricity pricing ; electric vehicle ; flexibility ; flexibility market ; home energy management system ; energy flexibility ; industrial energy management ; demand side management ; control approaches ; energy management ; optimization method ; objective function ; control constraints ; Demand Response ; dynamic thermal rating ; hosting capacity ; transformer ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The diversity of wood and non-wood forest products is enormous and reflected in their anatomical, physical and chemical properties as well as their potential applications. Special attention should be given to lesser-known species and even to invasive species, which may be profitable when properly managed, thereby decreasing the overexploitation of threatened species. Besides the market importance of stem wood, other tree components and non-wood forest products, often regarded simply as forest residual materials, are valuable forest resources with various potential applications that can strengthen the circular economy. Assessing the characteristics of these diverse materials, such as their structure and anatomy as well as their physical and chemical properties, is fundamental for evaluating their potential and increasing high-quality end-uses. This knowledge will also contribute to sustainable forest management with enhanced forest diversity and species conservation in addition to the reinforcement of certification and environmental policies.
    Keywords: Calamus zollingeri ; Calamus ornatus ; dynamic vapor sorption ; basic density ; volumetric swelling ; white rot ; mold ; Quercus suber L. ; seasonal variation ; cuticular waxes ; leaves ; new species ; morphology ; wood ; properties ; chemical composition ; spectroscopy ; chemometrics ; unconventional species ; Quercus suber ; cork borer ; cork ; phenolics ; tropical species ; wood anatomy ; wood density ; wood color ; multivariate analysis ; species diversity ; dark-brown zone ; lenticular filling tissue ; quantitative anatomical characteristics ; Quercus variabilis ; reproduction cork ; scanning electron microscopy ; sclereid ; virgin cork ; Cytisus scoparius ; liquefied ; optimization ; eco-valorization ; agro-industrial residues ; Asparagaceae ; lignocellulose ; crystalline cellulose ; syringyl/guaiacyl ; anatomy ; Tilia amurensis Rupr. ; Tilia mandshurica Rupr. & Maxim. ; branch ; wood properties ; papermaking material ; tropical timber ; color parameters ; mid-infrared spectroscopy ; FTIR ratios ; environmental factors ; West African Sahel ; Cupressus funebris Endl. wood ; wood knots ; physical properties ; wood color properties ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAL Forestry industry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: New scientific advances in different areas have allowed the design of more precise strategies for the prevention and treatment of metabolic disorders through nutrition. In this context emerges the term Precision Nutrition, a new approach that takes advantage of scientific knowledge about the interaction of internal and external environmental factors to develop dynamic and precise nutritional recommendations. Therefore, Precision Nutrition includes personalized advice based on genetics and well-documented gene–nutrient–phenotype interactions, as well as other factors such as individual metabolome, transcriptome, and microbiota profile; food behavior; and dietary, physical activity, and life-style habits; and the resulting interactomes. Precision Nutrition should be based at least on three sequential steps: conventional nutritional approaches (considering age, gender, and physiological states); the incorporation of nutritional and health status information (e.g., metabolites, physical and nutritional behavior); and the genetic baggage including multiomics functional integration.
    Keywords: dietary parameters ; carbohydrate intake ; obesity ; single nucleotide polymorphism ; CLOCK gene ; rs3749474 ; sodium intake ; hypertension ; single-nucleotide polymorphism ; personalized nutrition ; dietary vitamin A ; body fat ; UCP ; retinoic acid ; PBMC ; genetic variant ; weight loss ; nutrigenomics ; dietary intervention ; FTO gene ; dietary protein ; dietary carbohydrates ; dietary fat ; macronutrients ; gene-diet interaction ; glucose homeostasis ; glaucoma ; polygenetic-risk scores ; gene-gene interaction ; gene-nutrient interaction ; precision medicine ; childhood ; insulin resistance ; adipokine ; metabolomics ; biomarkers ; ELOVL ; metabolic alterations ; Mexican population ; Single Nucleotide Polymorphisms ; pediatrics ; cardiometabolic risk factors ; precision nutrition ; eating behavior ; nutrigenetics ; microbiota ; metabolic syndrome ; Mediterranean diet ; genetic risk score ; HELENA ; adolescents ; sex ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Keywords: QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 35
    Publication Date: 2024-04-05
    Description: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-11-17
    Description: This Special Issue provides a collection of recent research and reviews that investigate many areas of welfare assessment, such as novel approaches and technologies used to evaluate the welfare of farmed, captive, or wild animals. Research in this Special Issue includes welfare assessment related to pilot whales, finishing pigs, commercial turkey flocks, and dairy goats; the use of sensors or wearable technologies, such as heart rate monitors to assess sleep in dairy cows, ear tag sensors, and machine learning to assess commercial pig behaviour; non-invasive measures, such as video monitoring of behaviour, computer vision to analyse video footage of red foxes, remote camera traps of free-roaming wild horses, infrared thermography of effort and sport recovery in sport horses; telomere length and regulatory genes as novel biomarkers of stress in broiler chickens; the effect of environment on growth physiology and behaviour of laboratory rare minnows and housing system on anxiety, stress, fear, and immune function of laying hens; and discussions of natural behaviour in farm animal welfare and maintaining health, welfare, and productivity of commercial pig herds.
    Keywords: bioethics ; domestication ; genetic selection ; animal behavior ; animal welfare ; eye caruncle temperature ; Spanish Sport Horse ; performance test ; genetic lines ; heritability ; infrared thermography ; pigs ; welfare ; health ; herd management ; monitoring technologies ; animal husbandry ; welfare assessment ; wellbeing ; goat ; caprine ; dairy ; dairy cows ; heart rate ; sleep ; heart rate variability ; polysomnography ; animal-based welfare indicators ; camera traps ; wild horses ; precision swine farming ; ear tag pig sensor ; behavioral monitoring ; machine intelligence ; technology adoption ; broiler ; corticosterone ; performance ; telomeres ; telomere regulators ; stress biomarkers ; horse ; equine ; lying ; time budget ; locomotion ; geriatric ; orthopedic ; recumbency ; mixed commercial turkey flocks ; on-farm assessment ; YOLOv4 ; computer vision ; animal monitoring ; animal activity ; body posture ; rare minnow ; environmental enrichment ; growth ; physiology ; anxiety-like behavior ; enrichment ; hospitalization requirement ; lameness ; lesions ; tail biting ; attention bias ; conventional cage ; environmental complexity ; feather corticosterone ; IgA ; laying hen ; animal welfare assessment ; behaviour ; human intervention ; marine mammal ; cetacean ; management ; stranding ; wildlife ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: With the announcement of the European Green Deal, which defines a set of policy initiatives aimed at achieving a 50–55% reduction in carbon emissions by 2030 and making Europe climate neutral in 2050, the challenge of energy transition becomes even more critical. The transformation of national energy systems towards sustainability is progressing throughout all Central and Eastern European (CEE) countries, yet the goals and results are different. Most EU Member States have made substantial progress towards meeting their long-term commitments of emissions reductions. However, some bloc members have struggled to meet their obligations. An effective energy transition requires the introduction of appropriately designed policy instruments and of robust economic analyses that ensure the best possible outcomes at the lowest costs for society. In this context, this Special Issue aims to bring into the discussion the challenges that CEE countries have to face and overcome while undergoing energy transition.
    Keywords: climate change ; food security ; grand challenges ; multiple factor analysis ; regional studies ; renewable energy ; sustainable development goals ; support systems ; energy policy ; cogeneration ; capacity market ; individual cogeneration premium ; trade globalization ; financial globalization ; CO2 emissions ; real GDP per capita ; bootstrap panel Granger causality ; EU transition economies ; photovoltaics ; renewable energy sources ; “My Electricity” ; renewable energy policy ; Poland ; “Mój Prąd” ; grant ; renewable energy grants ; renewable energy support ; economic appraisal ; social discount rate ; Ramsey formula ; consumption rate of interest ; social opportunity cost ; renewable energy sources (RES) ; green energy transformation ; sustainable development ; energy cooperatives ; coopetition ; Renewable Energy Communities ; management ; households ; energy consumption ; platform ; EU ETS ; CO2 ; emissions trading ; energy companies from Central and Eastern Europe ; decarbonisation ; energy transition ; low-carbon technology ; climate and energy policy ; indicators ; biomass ; electric vehicle ; electromobility ; energy balance ; efficiency engines ; clustering ; charging stations ; data analysis ; hydrogen cells ; energy law ; customer preferences ; electric car ; PHEV ; driving technique ; limestone sorbents ; flue gas desulphurisation ; FGD gypsum ; coal-fired power plants ; climate policy ; capacity adequacy ; linear programming ; COVID-19 pandemic ; lockdown ; electricity demand profiles ; Polish energy mix ; energy transition in Poland ; social acceptance ; carbon emissions ; fleet electrification ; sustainable mobility ; fleet management ; energy mix ; onshore wind ; risk assessment ; cash-flows ; discount rate ; cost of capital ; cost of equity ; district heating ; decarbonization ; energy efficiency ; Hubgrade ; remuneration mechanism ; power generation ; new investments ; combined heat and power ; optimization ; thermal energy storage ; uncertainty ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The intention of this Special Issue is to focus on new aspects of drug discovery, including the search for new molecular targets of various diseases, the creation of new modern methods for diagnosing diseases, the development of new test systems and kits for assessing the selectivity and effectiveness of new drugs, the study of the molecular mechanisms of biologically active compounds, the formulation of new drugs, pharmacokinetic and pharmacodynamic studies, and preclinical trials of important molecules.
    Keywords: Streptococci ; antimicrobials ; QSAR ; MD simulation ; Kunitz-type peptides ; neuroprotective activity ; sea anemones ; TRPV1 ; P2X7R ; Parkinson’s disease (PD) ; diffuse large B cell lymphoma (DLBCL) ; deep neural network ; drug discovery ; drug combination ; biomarker ; cancer severity ; cancer prognosis ; MAFB ; tumor-associated macrophages ; prostate cancer ; photodynamic therapy ; magnetic resonance imaging ; ex vivo ; anti-inflammatory substance ; N-acylhydrazone ; naphthyl-N-acylhydrazone ; LASSBio-1524 analogues ; phosphacoumarin ; azomethine ylide ; cycloaddition ; anti-cancer ; cytotoxicity ; quantum chemistry ; pravastatin ; metformin ; radiation-induced intestinal injury ; minipigs ; epithelial regeneration ; inflammation ; arylazo sulfones ; DNA binding ; DNA cleavage ; DNA photocleavage ; A375 melanoma cells ; molecular docking ; radicals ; N–S bond homolysis ; platinum(II) ; five-coordinate complexes ; glycoconjugation ; cytotoxic activity ; protein X-ray structure ; lipophilicity ; natural products ; acetylcholinesterase inhibitors ; butyrylcholinesterase inhibitors ; Alzheimer’s disease ; central nervous system ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: Animal production (e.g., milk, meat, and eggs) provides valuable protein production for human beings and animals. However, animal production is facing several challenges worldwide such as environmental impacts and animal welfare/health concerns. In animal farming operations, accurate and efficient monitoring of animal information and behavior can help analyze the health and welfare status of animals and identify sick or abnormal individuals at an early stage to reduce economic losses and protect animal welfare. In recent years, there has been growing interest in animal welfare. At present, sensors, big data, machine learning, and artificial intelligence are used to improve management efficiency, reduce production costs, and enhance animal welfare. Although these technologies still have challenges and limitations, the application and exploration of these technologies in animal farms will greatly promote the intelligent management of farms. Therefore, this Special Issue will collect original papers with novel contributions based on technologies such as sensors, big data, machine learning, and artificial intelligence to study animal behavior monitoring and recognition, environmental monitoring, health evaluation, etc., to promote intelligent and accurate animal farm management.
    Keywords: pig weight ; body size ; estimation ; deep learning ; convolutional neural network ; pig identification ; mask scoring R-CNN ; soft-NMS ; group-housed pigs ; audio ; dairy cow ; mastication ; jaw movement ; forage management ; precision livestock management ; equine behavior ; wearable sensor ; intermodality interaction ; class-balanced focal loss ; absorbing Markov chain ; cow behavior analysis ; prediction of calving time ; cow identification ; EfficientDet ; YOLACT++ ; cascaded model ; instance segmentation ; generative adversarial network ; machine learning ; automated medical image processing ; deep neural network ; animal science ; CT scans ; computer vision ; cow ; extensive livestock ; sensorized wearable device ; monitoring ; parturition prediction ; radar sensors ; radar signal processing ; animal farming ; computational ethology ; signal classification ; wavelet analysis ; dairy welfare ; hierarchical clustering ; mutual information ; precision livestock farming ; time budgets ; unsupervised machine learning ; wearables design ; animal-centered design ; animal telemetry ; modularity ; smart collar ; design contributions ; additive manufacturing ; low-frequency tracking ; commercial aviary ; laying hens ; false registrations ; tree-based classifier ; animal behaviour ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-11-17
    Description: This book focuses on the modelling and the design process of gas bearings, on the experimental validation of such models, and on their applications. In particular, recent developments about foil bearings, aerostatic bearings, porous bearings, and non-contact precision positioning systems are shown.
    Keywords: aerostatic spindle ; fluid–structure interaction ; restrictor geometrical parameters ; structural dimension ; optimal design ; bump foil gas bearing ; thermo-hydrodynamic model ; temperature field ; thermal characteristics analysis ; foil bearing ; turbo machinery ; gas bearing ; industrial application ; air-bearing ; precision positioning ; tribotronics ; rotation accuracy ; roundness ; cylindricity ; dispersion coefficient ; gas bearings ; porous materials ; rotordynamics ; force coefficients ; aerostatic journal bearings ; porous bearing ; annular-thrust bearing ; numerical simulation ; finite element method ; dynamic coefficients ; eccentricity ; tilting ; tilting velocity ; partial arc ; PCB spindles ; dynamic identification ; logarithmic decrement method ; complex exponential method ; half-power method ; damping factor identification ; rigid rotor ; modal analysis ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 41
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: This book presents 22 of the accepted presentations at the 1st International Electronic Conference on Algorithms which was held completely online from September 27 to October 10, 2021. It contains 16 proceeding papers as well as 6 extended abstracts. The works presented in the book cover a wide range of fields dealing with the development of algorithms. Many of contributions are related to machine learning, in particular deep learning. Another main focus among the contributions is on problems dealing with graphs and networks, e.g., in connection with evacuation planning problems.
    Keywords: bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-03-21
    Description: One of the great challenges of contemporary society is establishing a sustainable way of life in harmony with the environment without compromising economic growth and technological development. On the other hand, the increase in the world population has driven per capita consumption, and consequently, the generation of waste. Because of this, new materials are being developed from different types of waste. This Special Issue aims to highlight and share recent scientific findings in the area of “New Environmentally Friendly and Sustainable Materials” manufactured from different material types (polymers, ceramics, metallics, and composites) and urban, industrial, mining and agricultural wastes. Moreover, scientific topics such as improving performance and durability, materials characterization, hybrid materials, foams and porous materials, trends and advances, and mechanical, electrical, magnetic, optical, and thermal properties will also be accepted.
    Keywords: palygorskite ; adsorption ; anionic dye ; cationic dye ; water treatment ; perlite tailings ; aggregate ; alkali–silicate reaction ; ceramic residue ; alkaline activation ; experimental design ; durability tests ; kaolin ; solid residues ; pozzolanic activity ; cement mortar ; carbonation ; poly (lactic acid) ; high-density biopolyethylene ; bioblends ; compatibilization ; scheelite tailings ; sustainable ceramic mass ; red ceramic ; firing parameters ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 43
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The range of human neurodegenerative diseases continues to pose significant unmet medical needs for societies around the world. The progressive and terminal nature of these conditions places a considerable personal burden on the individual affected but also on public health systems and health services. Tens of millions of people are indiscriminately affected by various dementias, which are rising at an alarming rate. There are no cures for many conditions, and it is clear that treatments applied as early as possible could greatly improve outcomes for patients. Therefore, new disease classification and diagnostic tools should be a key priority. Metabolomics represents a relatively new field of analytical science, which can be extremely useful in the early diagnosis of disease. The relatively unique feature of metabolites is that they sit at the intersection between the genetic background of an organism and its environment. Because many neurodegenerative diseases are not genetically inherited (instead having a range of known genetic risk factors and also a large number of unknown environmental triggers) the field of metabolomics offers great promise for the discovery of new, biologically, and clinically relevant biomarkers for neurodegenerative disorders. It is already bringing forward new knowledge in terms of the mechanisms of neurodegenerative disease.
    Keywords: QH301-705.5 ; Q1-390 ; glutamic acid ; n/a ; direct mass spectrometry ; neurodegeneration ; 6-OHDA ; targeted mass spectrometry ; mitochondrial dysfunction ; myo-inositol ; metabolomics ; bile acids ; subacute mild traumatic brain injury ; age-related macular degeneration ; metabolic pathways ; energy metabolism ; midbrain ; Alzheimer’s disease ; biomarkers ; 1H NMR ; Parkinson’s disease dementia ; GC-MS ; pathogenesis ; tricarboxylic acid cycle ; micro-dialysis ; 13C-labeled succinate ; metabolism ; lipidomics ; dementia with Lewy bodies ; fatty acid ; prodromal Parkinson’s disease ; malonate ; cerebral ischemia ; mass spectrometry ; retinal pigment epithelium ; excitotoxicity ; endothelin-1 ; reperfusion ; C. elegans ; Streptomyces venezuelae ; ?-synuclein aggregates ; natural product ; fatty acid metabolism ; imaging mass spectrometry ; LC-MS ; drusen ; cerebral palsy ; plasma ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 44
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.
    Keywords: QH301-705.5 ; SF1-1100 ; Q1-390 ; n/a ; muscle texture ; fractal analysis ; fish welfare ; Danio rerio ; motivation ; histopathology ; elevated phosphate concentrations ; sharks ; welfare ; African catfish (Clarias gariepinus) ; feed efficiency ; fighting ability ; aggressive interaction ; social rank ; boldness ; ethology ; fisheries management ; physiological response ; FishEthoBase ; welfare scores ; welfare criteria ; stress ; pain ; stereotypical behaviour ; Scyliorhinus canicula ; animal behavior ; welfare enhancement ; social communication ; nociception ; negative and positive affect ; aggression ; fertilisation success ; risk analysis ; aquaculture ; hematology ; Amyloodinium ocellatum ; framework ; structural complexity ; territorial ; growth ; positive welfare ; social stress ; age ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 45
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The re-use of industrial food residues is essential in the general framework of rational waste handling and recycling, which aims at the minimizing environmental impact of food production and producing functional food ingredients. Agri-food processing waste has long been considered a valuable biomass with a significant polyphenol load and profile. Polyphenols, aside from being powerful antioxidants that confer inherent stability to a variety of foods, may possess versatile bioactivities including anti-inflammatory and chemopreventive properties. The valorization of agri-food waste as a prominent source of polyphenols stems from the enormous amount of food-related material discharged worldwide and the emerging eco-friendly technologies that allow high recovery, recycling, and sustainable use of these materials. This book addresses the concept of recovering natural polyphenolic antioxidants from waste biomass generated by agri-food and related industrial processes and presents state-of-the-art applications with prospect in the food, cosmetic, and pharmaceutical industries.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; valorization ; ultrasound assisted extraction ; microwave assisted extraction ; Box–Behnken design ; HPLC-DAD-q-TOF-MS ; Dioscorea batatas ; green oleo-extraction ; grape marc ; quantitative analysis ; natural antioxidants and flavors ; antioxidant ; infrared-assisted extraction ; anti-ageing ; anthocyanins ; liquid chromatography-mass spectrometry ; Chinese yam ; functional food ; extraction ; olive mill wastewater ; adsorbents ; relative solubility simulation ; HPLC-fluorometric detector (FLD)–MS ; saffron ; antioxidants ; food-grade solvents ; Mango ; zero-waste biorefinery ; response surface methodology ; ophthalmic hydrogel ; olive leaves ; sonotrode ultrasonic-assisted extraction ; vegetable oils and derivatives ; anti-inflammatory ; skin whitening ; phenolics ; Brewers’ spent grains ; proanthocyanidins ; brewer’s spent grain ; anti-inflammatory and antioxidant activity ; antimicrobial activity ; by-products ; antiplatelet activity ; phenanthrenes ; wine lees ; bioactive compounds ; deep eutectic solvents ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The aim of this Special Issue is to gather recent advances and development in target tracking techniques to determine how they can be adapted for modern radar and sonar systems. After peer review, 17 articles in related areas have been accepted for publishing in this Special Issue. The published articles cover a range of topics and applications central to target tracking. There are eight papers about general multi-target tracking, including the topics of joint tracking and classification [3], adaptive estimation using clutter measurement probability [6], joint localization and tracking [7], extended target tracking [8], tracking with smoothing [11], DOA tracking [12], tracking under low detection probability [14], and sonar tracking and interception [17]. Three papers address multi-sensor multi-target tracking methods. Specifically, a multi-target estimating method for pulsed radar systems is proposed in [2], a joint dwell time and bandwidth optimization method in a radar network is proposed in [4], a and multiple marine ship tracking method with unknown backgrounds is presented in [9]. There are 2 papers [10,15] on the problem of target assignment in multi-sensor multi-target tracking. Moreover, Mallick et al. considered measures of nonlinearity of a polynomial curve in two dimensions [1], Zhao et al. explored the use of calibration targets for which the positions are known to the MPR system, to counter the loss in target localization accuracy arising from transmitter/receiver position errors [13], and Li et al. proposed an algorithm to apply the frequency diversity technique to passive azimuth estimation in [16].
    Keywords: Target tracking ; target detection ; radar system ; sonar system ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 47
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Thanks to their rich chemodiversity, marine natural products represent a unique source of new bioactive metabolites. As the new leading compounds in drug discovery and development, these molecules may represent challenges for the treatment of a number of human diseases, attracting the attention of many researchers during their chemical and biological studies. This Special Issue covers all fields of drugs research in which marine natural products are involved, including their isolation and characterization, biological activities, and medicinal applications as well as synthetic approaches and their related analogues. The cover picture shows “The Nudibranch mollusk Godiva quadricolor on a sponge, reflected under the surface during the low tide. Fusaro Lagoon, Bacoli (Naples)”.
    Keywords: alginate ; Sargassum duplicatum ; okra ; antioxidant ; diabetic ; wound healing ; sulfavant ; sulfoquinovosyldiacylglycerols ; sulfoglycolipids ; mass spectrometry ; UHPLC-MS ; lipids ; cancer therapy ; gold nanoparticles ; marine products ; natural products ; photosensitizer ; purpurin 18 ; reactive oxygen species ; seaweed ; biosilica ; diatom frustule ; sustainable production ; drug delivery ; Sargassum ilicifolium ; mangosteen rind ; diabetic mice ; Aquimarina sp. ; diketopiperazine ; N-phenethylacetamide ; epithelial-mesenchymal transition (EMT) ; A549 cells ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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  • 48
    Publication Date: 2023-04-05
    Description: This reprint includes papers from different research fields, reflecting the sectional talks presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, which took place in June 2021. The objective of the 2021 Conference was to bring together perspectives and challenges in doctoral research in a common forum and to provide a platform enabling doctoral researchers to meet and share state-of-the-art developments in their fields. It consists of 16 papers presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, in several fields such as: mechanical and industrial engineering, food science and biotechnology, electrical/electronic engineering, systems engineering and information technologies, chemistry, electrochemistry, and economic models and strategies.
    Keywords: incremental pumps ; profiling of generating tools ; helical surfaces ; Romania ; coastal area ; wind energy ; measurements ; IEC classes ; wind turbines ; mass tourism ; management model ; Constanta ; PESTEL ; Black Sea ; sustainability ; eggplant peels ; bioactive compounds ; hydrogels ; anthocyanins ; beetroot peel ; betalains ; polyphenols ; CCD-RSM ; optimal control ; metaheuristic algorithms ; evolutionary algorithms ; simulation ; ventilation on ships ; HVAC requirements ; COVID-19 ; spread the disease ; airborne transmission ; HEPA filtration ; UV disinfection ; heat recovery ; L-tryptophan ; polypyrrole ; sensor ; amino acid ; cyclic voltammetry ; chronoamperometry ; atorvastatin ; carbon nanotubes ; gold nanoparticles ; Hippophae rhamnoides L. ; carotenoids ; flavonoids ; antioxidant activity ; microencapsulation ; modulation ; electromagnetic disturbances ; electromagnetic compatibility ; military ship ; communication systems ; navigation conditions ; Danube River ; management tool ; quality function deployment ; house of quality ; enwrapping surfaces ; profiling ; geometrical methods ; tower ; wind turbine ; load ; offshore wind ; marine renewable energy ; living labs ; design thinking ; coastal zone ; integrated coastal zone management (ICZM) ; Romanian coastal zone ; Black Sea basin ; wind parameters ; historical data ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCM Development economics & emerging economies
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  • 49
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Mycotoxins are secondary metabolites produced by molds. Although the primary role of these toxins is thought to be related to the colonisation of the environment by the fungi—mycotoxins are able to kill other micro-organisms (antimicrobial effect) and/or plant cells (mycotoxin-producing fungi being necrophagic)—the exposure of animals and humans to mycotoxins through the consumption of mycotoxin-contaminated food and feeds leads to diseases and death. Among the different mycotoxins described (more than 350 mycotoxins have been identified), deoxynivalenol (DON or vomitoxin) produced by Fusarium species has attracted the most attention due to its prevalence and toxicity. DON is part of a family of mycotoxins called trichothecenes that are small sesquiterpenoids with an epoxide group at positions 12–13 allowing their binding to ribosomes causing the so-called ribosome stress response, characterized by the activation of various protein kinases that lead to alterations in gene expression and cellular toxicity in animals, humans and plants. Here, we compiled very recent findings regarding DON and its derivatives: i) their prevalence in human food; ii) the estimation of the exposure of humans to them using biological markers; iii) their roles during plant–fungi interaction; iv) the alteration caused by them in animals and humans, particularly at low doses that are close to those observed in farm animals and human consumers; v) possible strategies to decrease their presence in food and feeds. Overall, this book will give the reader a clear and global view on this important mycotoxin produced by Fusarium species which is responsible for huge economic loss and health issues.
    Keywords: QH301-705.5 ; cell entry ; deoxynivalenol ; DON derivative ; cell effect ; trichothecene ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 50
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Fire regimes (occurrence, cycle, severity, size, etc.) are key factors in many forest ecosystems, as they are often critical drivers of forest composition, dynamics, and ecosystem processes. Fire regimes vary in space and time according to climatic, physical and biological factors. A better understanding of the interacting factors controlling fire regimes may contribute to improving fire and forest management and their future projection in the context of global change. Knowledge of how fire regimes affect natural landscapes is also used in forestry as a template to manage the forest for wood production. This approach, keeping biodiversity and ecological processes associated with natural fire regimes, may also help in maintaining forest productivity and resilience in the face of climate change. This Special Issue aims to synthesize current understanding of factors affecting fire regime characteristics, to present recent research on fire regimes and their effects on forest ecosystems, and to illustrate how this knowledge could be translated into forest or fire management strategies in the context of global change.
    Keywords: QH301-705.5 ; Fire regime ; Natural disturbances ; Wildfire ; Global change ; Forest management ; Forest ecosystems ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 51
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: This Urological Cancer 2020 collection contains a set of multidisciplinary contributions to the extraordinary heterogeneity of tumor mechanisms, diagnostic approaches, and therapies of the renal, urinary tract, and prostate cancers, with the intention of offering to interested readers a representative snapshot of the status of urological research.
    Keywords: renal cell carcinoma ; iron ; macrophages ; chelation therapy ; urothelial carcinoma ; transcriptome ; microtubule ; MAP1B ; prognosis ; KLF5 ; androgen receptor ; cell proliferation ; tumorigenesis ; prostate cancer ; precision medicine ; whole genome sequencing ; optical mapping ; therapy ; prostate carcinoma ; prostate mpMRI ; machine learning ; artificial intelligence ; deep learning ; neural network ; angiogenesis ; angiogenic growth factors ; antiangiogenic therapy ; renal tumors ; prevention ; α1-adrenoceptor antagonists ; anoikis ; vascularity ; research model ; oncogenes ; tumor suppressor genes ; MR-guided ; radiotherapy ; MRgRT ; stereotactic ablative radiotherapy ; stereotactic ablative radiation therapy (SABR) ; renal cell cancer ; RCC ; online adaptive ; [68Ga]Ga-PSMA PET/CT ; dual-time point imaging ; delayed imaging ; biphasic imaging ; lesion positivity rate ; CXCL9 ; PD1 ; PD-L1 ; stage T1 NMIBC ; prostatic neoplasms/mortality ; prostatic neoplasms/epidemiology ; SEER Program ; bladder cancer ; transurethral resection ; en-bloc resection ; CPT1A ; fatty acids ; serine ; androgen response ; ROS ; oxidative stress ; DONSON ; Downstream Neighbor of SON ; biomarker ; metastatic spread ; diagnosis ; differential diagnosis ; histopathology ; immunohistochemistry ; stroma signature ; patient-derived xenografts ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 52
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Due to the intensive development of the global economy, many problems are constantly emerging connected to the safety of ships’ motion in the context of increasing marine traffic. These problems seem to be especially significant for the further development of marine transportation services, with the need to considerably increase their efficiency and reliability. One of the most commonly used approaches to ensuring safety and efficiency is the wide implementation of various automated systems for guidance and control, including such popular systems as marine autopilots, dynamic positioning systems, speed control systems, automatic routing installations, etc. This Special Issue focuses on various problems related to the analysis, design, modelling, and operation of the aforementioned systems. It covers such actual problems as tracking control, path following control, ship weather routing, course keeping control, control of autonomous underwater vehicles, ship collision avoidance. These problems are investigated using methods such as neural networks, sliding mode control, genetic algorithms, L2-gain approach, optimal damping concept, fuzzy logic and others. This Special Issue is intended to present and discuss significant contemporary problems in the areas of automatic control and the routing of marine vessels.
    Keywords: collision avoidance ; ship domain ; fuzzy inference ; collision risk ; early warning system ; marine vessel ; tracking controller ; stability ; functional ; optimal damping ; fin stabilizer ; ship turning ; heel/roll reduction ; L2-gain ; uncertainty ; non-linearity ; ship motion control ; path-following ; guidance algorithm ; nonlinear feedback ; AIS Data ; trajectory prediction ; waterway transportation ; neural networks ; autonomous navigation ; multi-joint autonomous underwater vehicle (MJ-AUV) ; 3-dimensional modeling ; LQR ; LESO ; multicriteria route planning ; genetic algorithm ; particle swarm optimization ; oceanic meteorological routing ; cooperative game theory ; supply chain management ; supply disruption ; unmanned surface vehicle ; Guidance, Navigation and Control ; course keeping ; adaptive sliding mode ; unmanned surface vehicle (USV) ; system identification ; traditional neural network ; physics-informed neural network ; zigzag test ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 53
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer’s disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms and therapeutic potentials of repositioning drugs and new agents for Alzheimer’s disease and related dementias. These findings are expected to contribute to the development of innovative strategies for the prevention and treatment of such diseases.
    Keywords: activation phenotypes ; microglia ; neuroinflammation ; immunohistochemistry ; temporal cortex ; Alzheimer’s disease ; amyloid ; amyloid β-protein (Aβ) ; mAb158 ; oligomers ; protofibrils ; amyloid aggregation ; supported lipid bilayers ; time-lapse AFM ; molecular dynamics simulation ; alzheimer’s disease ; amyloid β ; bryostatin-1 ; ECE1 ; iPS ; nELAV ; neurotoxicity ; oligomer ; protein kinase C ; α-secretase ; APP mutation ; recessive inheritance ; familial Alzheimer’s disease ; Aβ oligomers ; amyloid imaging ; microbiota ; bacterial amyloid ; FUBA ; curli ; CsgA ; amyloid beta ; oxidative stress ; supplement ; phosphodiesterase III inhibitor ; cerebral micro-hemorrhage(s) ; cerebral amyloid angiopathy ; amyloid-β protein ; transgenic mice ; NMR ; CD ; Aβ ; β-amyloid peptide ; α/β-discordant ; Dutch-type mutation ; E22Q ; FAD ; Amyloid β ; Polyphenol ; Pro-oxidant ; Alzheimer’s Disease ; molecular imaging ; amyloid β-peptides ; islet amyloid polypeptide ; high-speed atomic force microscopy ; amyloid PET ; tau PET ; amyloid precursor protein ; mutation ; cerebellum ; PBB3 ; PiB ; axon ; traditional medicines ; Polygalae Radix ; diosgenin ; naringenin ; kihito ; amyloid-β ; antimicrobial ; antiviral ; antimicrobial peptide ; neurodegenerative disease ; misfolding ; fluorescence microscopy ; FRET ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 54
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Concerns have been raised with respect to the state of high-altitude and high-latitude treelines, as they are anticipated to undergo considerable modifications due to global changes, and especially due to climate warming. As high-elevation treelines are temperature-limited vegetation boundaries, they are considered to be sensitive to climate warming. As a consequence, in this future, warmer environment, an upward migration of treelines is expected because low air and root-zone temperatures constrain their regeneration and growth. Despite the ubiquity of climate warming, treeline advancement is not a worldwide phenomenon: some treelines have been advancing rapidly, others have responded sluggishly or have remained stable. This variation in responses is attributed to the potential interaction of a continuum of site-related factors that may lead to the occurrence of locally conditioned temperature patterns. Competition amongst species and below-ground resources have been suggested as additional factors explaining the variability in the movement of treelines. This Special Issue (book) is dedicated to the discussion of treeline responses to changing environmental conditions in different areas around the globe.
    Keywords: QH301-705.5 ; QK1-989 ; Q1-390 ; n/a ; tree seedling recruitment ; shrubline ; light quality ; higher altitude ; precipitation ; experimental rain exclusion ; Pinus cembra ; Changbai Mountain ; treeline dynamics ; fungal ecology ; thermal continentality ; tree regeneration ; elevational transect ; monitoring ; conifer shrub ; plant water availability ; permafrost ; foehn winds ; treeline ; Holocene ; nitrogen cycling ; carotenoids ; timberline ; 15N natural abundance ; spectrometer ; basal area increment ; palynology ; xylem embolism ; diversity ; elevational treeline ; European Alps ; temperature ; tree line ; winter stress ; photosynthetic pigments ; Pinus sibirica ; westerly winds ; relative air humidity ; ecosystem manipulation ; Larix decidua ; microsite ; polar treeline ; Central Austrian Alps ; Switzerland ; multi-stemmed growth form ; conifers ; forest edge ; history of treeline research ; soil drought ; dendroclimatology ; knowledge engineering ; Rocky Mountains ; apical control ; cloud ; postglacial ; alpine timberline ; space-for-time substitution ; climate change ; expert elicitation ; shoot elongation ; pit aspiration ; climate warming ; climate zone ; alpine treeline ; refilling ; Abies sibirica ; growth trend ; western Montana ; light quantity ; Picea abies ; Mediterranean climate ; forest climatology ; altitude ; environmental stress ; sub-Antarctic ; Erman’s birch ; photoinhibition ; tocopherol ; elevational gradients ; NDVI ; long-term trends ; sap flow ; peat ; tree seedlings ; Southern Ocean ; chlorophyll ; non-structural carbohydrates (NSCs) ; drought ; upward advance ; remote sensing data ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 55
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: This Special Issue, “Plant Oxidative Stress: Biology, Physiology, and Mitigation”, published 11 original research works and 1 review article that discussed the various aspects of ROS Biology, metabolism, and the physiological mechanisms and approaches to mitigating oxidative stress. These types of research studies show further directions for the development of crop plants that are tolerant to abiotic stress in the era of climate change.
    Keywords: heat stress ; grafting ; cucumber ; bitter-melon rootstock ; polyamines ; photosynthesis ; salicylic acid ; chlorophyll fluorescence ; excess boron ; lipid peroxidation ; enzymatic antioxidant ; glutathione ; proline ; stomatal conductance ; arsenic stress ; soybean ; growth ; antioxidant enzymes ; ascorbate–glutathione cycle ; glyoxalase system ; altitudinal variation ; antioxidant activity ; bioactive compounds ; endemic species ; oxidative damage ; sequential application of antioxidants ; salinity ; Cucumis sativus ; photosynthetic efficiency ; antioxidant defense systems ; antioxidants ; cadmium ; oxidative stress ; peptone ; spinach ; alpha-tocopherol ; foliar spray ; okra varieties ; salt ; drought ; plants ; ROS ; genomics ; approaches ; integration ; abiotic stress ; antioxidant defense ; phytohormones ; pulse crop ; water deficit ; AsA-GSH pathway ; methylglyoxal ; micronutrient ; osmoregulation ; reactive oxygen species ; trace elements ; Olea europaea L. ; selenium biofortification ; olive pollen ; cytosolic Ca2+ ; Cucurbita pepo (L.) ; mineral uptake ; nucleic acids ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PST Botany & plant sciences
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  • 56
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Water resource systems planning and management issues are often very complex. The pressures on water resources are increasing with the expanding scale of global development involving ecological and hydrological consequences in river basins and groundwater aquifers, and water-quality deterioration. All this leads to the increasing need for investigating the effects of different human influences and impacts on the hydrological regime and on water quality like as land-use changes, climatic variability and climate changes, and intensified water and land-use practices. The Special Issue “Advances in Flow Modeling for Water Resources and Hydrological Engineering” presents a collection of scientific contributions that provides a sample of the state-of-the-art and forefront research in this field. In particular, basin-wide water resources planning, watershed management, flood forecasting, droughts, climate change impacts on flood risk and water resources, reservoir operation and management, river morphology and sediment transport, river water quality, and irrigation were the main research and practice targets that the papers published in this Special Issue aimed to address.
    Keywords: stream discharge ; near-natural catchment ; trend analysis ; NW Spain ; field-scale hydrological models ; DRAINMOD ; tile drainage ; nitrate leaching ; climate change ; venturi flume ; CFD ; OpenFOAM ; RANS ; turbulence model ; numerical simulation ; Parshall flume ; water balance ; Thornthwaite–Mather method ; Python ; serverless computing approach ; watershed hydrology ; Yukon River plume ; river discharge ; sediment load ; flocculation ; plunging ; underflow ; flood ; geological categories ; probability ; Medvednica Mt. ; Croatia ; numerical model ; shallow water equations ; dam break ; dry and wet beds modeling ; river flow ; open channels ; eddy viscosity ; parabolic profile ; streamwise velocity distribution ; turbulent kinetic energy (TKE) ; mixing length ; log law ; log wake ; hydrological modeling ; streamflow ; SWAT ; Venturi flume ; nonlinear model ; burned areas ; hydrological modelling ; infiltration capacity ; SCS-CN ; post-fire ; shock wave ; spillway ; spillway pier ; flat chute ; physical modeling ; hydrology ; tiling ; subsurface flow ; Iowa ; variational ensemble forecasting ; hydrologic processing strategies or hypotheses ; SR2MR streamflow forecasting ; real-time hydrologic forecasting system ; satellite precipitation products ; multi models ; best streamflow prediction ; inverse variance weighting ; inverse probability weighting ; representative concentration pathways 4.5 and 8.5 ; modified Mann–Kendall trend test ; Ziway Lake Basin ; Rift Valley ; Ethiopia ; maximum precipitation ; maximum flow ; gravel bed rivers ; skin friction ; flow resistance ; bed forms ; energy slope ; boundary layer characteristics ; abrupt negative step ; hydraulic jump ; energy loss ; momentum closure ; Boussinesq equations ; specified intervals ; MODIS ; evapotranspiration ; multi-variable calibration ; regional flood frequency ; ungauged catchments ; direct rainfall modelling ; headwater catchments ; Australia ; drought ; water ; water resources modelling ; flood forecast ; climate-change impacts ; river quality ; river morphology ; watershed management ; reservoir management ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 57
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: According to the National Research Council, the use of embedded systems throughout society could well overtake previous milestones in the information revolution. Mechatronics is the synergistic combination of electronic, mechanical engineering, controls, software and systems engineering in the design of processes and products. Mechatronic systems put “intelligence” into physical systems. Embedded sensors/actuators/processors are integral parts of mechatronic systems. The implementation of mechatronic systems is consistently on the rise. However, manufacturers are working hard to reduce the implementation cost of these systems while trying avoid compromising product quality. One way of addressing these conflicting objectives is through new automatic control methods, virtual sensing/estimation, and new innovative hardware topologies.
    Keywords: independent-wheel drive ; steering assistance ; nonlinear system ; active disturbance rejection control ; smooth road feeling ; city bus transport ; electric vehicles ; electrification ; software tool ; planning ; control ; charging management ; simulation ; analysis ; energy management ; hybrid electric vehicle ; powertrain electrification ; equivalent consumption minimization ; supercharging ; hardware-in-the-loop experiments ; driving force distribution ; decentralized traction system ; 4WD electric vehicle ; energy efficiency ; traction control ; efficiency optimization ; air mobility ; fuel cell hybrid aircraft ; stochastic optimal control ; drift counteraction optimal control ; normal force estimation ; unbiased minimum variance estimation ; controller output observer ; youla parameterization ; adaptive cruise control ; automated driving ; energy-saving ; fuel-saving ; optimal control ; passenger comfort ; new energy vehicles ; speed prediction ; macroscopic traffic model ; traffic big-data ; deep learning ; vehicle lateral dynamic and control ; unresolved issues ; application of speed prediction ; electric vehicle ; hybrid vehicle ; lithium ion ; ultracapacitor ; battery aging ; EHB ; EMB ; EWB ; system modeling ; bond graph ; optimization ; control design ; Youla parameterization ; robust control ; nonlinear optimization ; brake-by-wire ; actuator ; electro-mechanical brake ; electronic wedge brake ; electro-hydraulic brake ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 58
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Forests cover 30% of the Earth’s land area, or nearly four billion hectares. Enhancing the benefits and ecosystem services of forests has been increasingly recognized as an essential part of nature-based solutions for solving many emerging global environmental problems today. A core science supporting forest management is understanding the interactions of forests, water, and people. These interactions have become increasingly complex under climate change and its associated impacts, such as the increases in the intensity and frequency of drought and floods, increasing population and deforestation, and a rise in global demands for multiple ecosystem services including clean water supply and carbon sequestration. Forest watershed managers have recognized that water management is an essential component of forest management. Global environmental change is posing more challenges for managing forests and water toward sustainable development. New science on forest and water is critically needed across the globe. The International Forests and Water Conference 2018, Valdivia, Chile (http://forestsandwater2018.cl/), a joint effort of the 5th IUFRO International Conference on Forests and Water in a Changing Environment and the Second Latin American Conference on Forests and Water provided a unique forum to examine forest and water issues in Latin America under a global context. This book represents a collection of some of the peer-reviewed papers presented at the conference that were published in a Special Issue of Forests.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; social capital ; Cambodia ; forest and water policy ; land use and land cover change ; shrubland ; “Forests to Faucets” ; precipitation gradient ; forest ecosystem management ; afforestation ; connectivity ; land use change ; forest operations ; Chile ; catchment management ; forest plantation ; climate change ; compound wildfire-water risk ; native forest ; hydrology ; wetland ; streamside native buffer ; sustainability ; participatory monitoring ; hydrological modeling ; timber harvesting ; water quality ; native forests ; source water protection ; global change ; forest hydrology ; community drinking-water ; SDGs ; drinking-water security ; Oregon ; forest ; aquatic-riparian ecosystems ; NDC ; heat: moisture index ; watershed management ; load ; Rhyacotriton ; ecohydrology ; nutrient concentrations ; multi-criteria analysis ; Loess Plateau ; dissolved organic matter ; US Pacific Northwest ; soil moisture ; agricultural lands ; water management ; water provision ; water supply ; forests ; post-fire hydrology ; grassland ; forest plantations ; restoration strategy ; riparian buffer zones ; Mekong ; riparian vegetation ; density management harvest ; SWAT model ; forest watersheds ; water governance ; Nenjiang River ; forestry ; ecosystem services ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 59
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: In the last few years, huge amounts of progress have been made regarding remote sensing in the field of computer vision. This success and progress is mostly due to the effectiveness of deep learning (DL) algorithms. In addition, the remote sensing community has shifted its attention to DL, and DL algorithms have been used to achieve significant success in many image analysis tasks. However, with regard to remote sensing, a number of challenges caused by difficulties in data acquisition and annotation have not been fully solved yet. This reprint is a collection of novel developments in the field of remote sensing using computer vision, deep learning, and artificial intelligence. The articles published involve fundamental theoretical analyses as well as those demonstrating their application to real-world problems.
    Keywords: tropical cyclone detection ; meteorological satellite images ; deep learning ; deep transfer learning ; generative adversarial networks ; image target detection ; multiple scales ; any angle object ; remote sensing of small objects ; point clouds ; 3D tracking ; state estimation ; Siamese network ; deep LK ; convolutional neural networks (CNNs) ; multilayer feature aggregation ; attention mechanism ; remote sensing image scene classification (RSISC) ; hyperspectral image classification ; variational autoencoder ; generative adversarial network ; crossed spatial and spectral interactions ; crater detection algorithm (CDA) ; R-FCN ; self-calibrated convolution ; split attention mechanism ; transfer learning ; remote sensing ; oriented object detection ; rotated inscribed ellipse ; remote sensing images ; keypoint-based detection ; gated aggregation ; eccentricity-wise ; object detection ; remote sensing image ; anchor free ; oriented bounding boxes ; deformable convolution ; three-dimensional radar imaging ; convolution neural network ; super-resolution ; side-lobe suppression ; terahertz radar ; aerial image generation ; satellite image generation ; structure map ; style vector ; high resolution image ; self-constructing graph ; semantic segmentation ; GAN ; image generation ; data augmentation ; remote sensing disaster image ; convolutional neural network ; double-stream structure ; feedback ; encoder–decoder network ; dense connections ; instance segmentation ; Swin transformer ; cascade mask R-CNN ; remote sensing image retrieval ; hashing algorithm ; binary code ; triplet ordinal relation preserving ; cross entropy ; feature distillation ; forest fire ; smoke segmentation ; Smoke-Unet ; residual block ; Landsat-8 ; band sensibility ; unsupervised domain adaptation ; bidirectional domain adaptation ; image-to-image translation ; generative adversarial networks (GANs) ; U-Net ; high-density laser scanning ; logging trails ; digital surface model ; canopy height model ; commercial thinning ; convolutional neural networks ; multiview ; satellite and UAV image ; joint description ; image matching ; neural network ; contextual information ; Anchor Free Region Proposal Network ; polar representation ; 3D object detection ; point cloud ; sampling ; single-stage ; rotated object detection ; angle-based detector ; angle-free framework ; rotated region of interests (RRoIs) ; representative points ; plastic ; UAVs ; contrastive learning ; mutual guidance ; spatial misalignment ; vehicle detection ; ANN ; automatic classification ; risk mitigation ; machine learning ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 60
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-08-12
    Description: This reprint describes recent advances made in the field of antifungal development, especially the discovery of new drugs and drug repurposing. The articles presented in this book provide useful information and insight for the development of new antifungal drugs or intervention strategies. The identification of new, safe molecules, and cellular targets, as well as the elucidation of their antifungal mechanisms of action, will further the effective control of fungal pathogens, especially those resistant to current therapeutic agents.
    Keywords: nanoparticles ; fungi ; drug delivery systems ; marine ; biological synthesis ; myconanotechnology ; canesten ; clotrimazole ; vulvovaginal ; vaginitis ; mycosis ; candidosis ; yeast infection ; candida ; candida albicans ; vaginal health ; anticandidal activity ; indazole ; pyrazole ; 3-phenyl-1H-indazole ; drug design ; acetylsalicylic acid (ASA, aspirin) ; capsule ; CAP64 ; Cryptococcus ; membrane potential (ΔΨM) ; photodynamic treatment ; photosensitiser ; ultrastructure ; drug repurposing ; antifungals ; repositioning ; yeasts ; emerging fungi ; multidrug resistance ; therapeutic alternatives ; new targets ; Candida auris ; Aspergillus spp. ; antifungal ; beta-glucan ; polycations ; Galleria mellonella model ; retinoids ; Candida spp. ; onychomycosis ; Malassezia spp. ; dermatophytes ; microbiology ; mycology ; all-trans retinoic acid ; Acanthamoeba ; free-living ameba ; Acanthamoeba keratitis ; isavuconazonium sulfate ; cyst ; drug ; drug discovery ; drug targets ; invasive aspergillosis treatment ; invasive fungal infections ; fission yeast ; cell wall ; β(1,3)-D-glucan synthase ; antifungal drugs ; echinocandin drugs ; echinocandin resistance ; Fks resistance hot spots ; cytokinesis ; septation ; cell separation ; cell integrity ; cell lysis ; sporotrichosis ; Felis catus ; quinones ; hydrazones ; zoonoses ; host-directed drug therapy ; azoles ; polyenes ; echinocandins ; viral infections ; azole ; synergy ; resistance ; Candida ; natural products ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-24
    Description: This reprint contains contributions focusing on recent developments in the design, synthesis, and characterization of nanocatalysts intended for applications in environmental protection and low carbon footprint power generation processes thanks to the overall effort of scientists and researchers for a cleaner and more sustainable future. New synthetic approaches to the production and in-depth characterization of innovative nanostructured composites and hybrid materials with well-controlled textural and surface chemistry properties that give performance advantages in a variety of important environmental and energy applications such as CO2 utilization/recycling, hydrogen and syngas production, biosensing, and biocatalysis as well as in ways to obtain useful materials from waste are included, among others. This reprint is the result of one of the cutting-edge Special Issues in the field of Nanoscience and Nanotechnology organized by Nanomaterials to celebrate its 10th anniversary.
    Keywords: nanocarbon ; rocket fuels ; furfuryl alcohol ; fuming nitric acid ; waste ; hypergolics ; carbon materials ; CO2 methanation ; bimetallic catalysts ; Ni-based catalysts ; promoters ; alloy nanoparticles ; bimetallic synergy ; hybrid nanoflowers ; biosynthesis ; influencing factors ; biosensing cues ; bio-catalysis ; propane ; steam reforming ; hydrogen production ; perovskite ; ruthenium ; rhodium ; La2O2CO3 ; stability ; propane steam reforming ; H2 production ; Ni ; TiO2 ; CeO2 ; YSZ ; ZrO2 ; Al2O3 ; drifts ; n/a ; HDO reaction ; transition metal phosphides ; structure ; acidity ; characterization ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    Publication Date: 2023-09-11
    Description: This Proceedings reprint is a collection of papers from the E-Textiles 2022 Conference and represents the state of the art from both academia and industry in the development of smart fabrics that incorporate electronic and sensing functionality. The Proceedings reprint presents a wide range of applications of the technology, including wearable textile devices for healthcare applications such as ECG measurements and functional electrical stimulation. Manufacturing approaches include printed smart materials, knitted e-textiles and flexible electronic circuit assembly within fabrics and garments. Supplying power is a constant challenge for all wireless wearable technologies, and therefore this collection includes papers on triboelectric energy harvesting and zinc-ion batteries fabricated on top of textile substrates.
    Keywords: electronics ; wearables ; smart fabrics ; e-textiles ; sensing ; healthcare devices ; textile antennas ; energy harvesting ; printed electronics ; knitted e-textiles ; functional yarns&nbsp ; &nbsp ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Additive manufacturing (AM) has been at the center of attention of studies and industry. The AM process involves gradual build-up in layers, and capability in the fabrication of complex shapes with low cost. Advances in the processing of polymers and polymer composites with this method are in the domain of this journal, which can provide a vital resource for anyone involved in additive manufacturing. This Special Issue cover original reviews and research articles dedicated to: AM processes of manufacturing and materials; Process–microstructure/morphology–properties relationships; Optimization of process parameters; Mechanical properties of fabricated parts; Modeling and simulation.
    Keywords: hybrid bio-inspired design ; nacre ; woodpecker beak ; mechanical performance ; failure mode ; finite element simulation ; Taguchi design ; ANOVA ; FFF ; response surface ; cylindricity ; process optimization ; polymer gear ; additive manufacturing ; differential pressure vacuum casting ; polyurethane resin ; abrasion ; fused filament fabrication ; temperature distribution modelling ; dynamic and static model ; thermal history ; impeller ; polymers ; polymer composites ; manufacturing process ; conventional manufacturing ; injection moulding ; performance ; face mask ; medical devices ; filtration performance ; 3D reconstruction ; customized implant ; PEEK ; accuracy evaluation ; finite element analysis ; 3D printing ; fused deposition modeling ; tensile testing ; infill rate ; crystallizable PET ; micromechanical model ; viscoplasticity ; temperature effect ; biaxial loading ; polylactic acid (PLA) ; dimensional deviation ; definitive screening design ; desirability function ; material extrusion ; rheological behavior ; mechanical properties ; temperature profile ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: The worldwide emergence of antimicrobial-resistant bacteria, specially those resistant to last-resource antibiotics, is now a common problem being defined as one of three priorities for the safeguarding of One Health by the Tripartite Alliance, which includes the World Health Organization (WHO), the Food and Agriculture Organization (FAO) and the Office International des Epizooties (OIE). Bacteria resistance profiles, together with the expression of specific virulence markers, have a major influence on the outcomes of infectious diseases. These bacterial traits are interconnected, since not only the presence of antibiotics may influence bacterial virulence gene expression and consequently infection pathogenesis, but some virulence factors may also contribute to an increased bacterial resistance ability, as observed in biofilm-producing strains. The surveillance of important resistant and virulent clones and associated mobile genetic elements is essential for decision making in terms of mitigation measures to be applied for the prevention of such infections in both human and veterinary medicine. However, the role of natural environments as important components of the dissemination cycle of these strains has not been consider until recently. This Special Issue aims to publish manuscripts that contribute to the understanding of the impact of bacterial antimicrobial resistance and virulence in the three areas of the One Health triad–i.e., animal, human and environmental health.
    Keywords: MRSA ; EMRSA-15 ; MLSB ; bacteremia ; bloodstream infections ; antibiotic resistance ; aquatic contamination ; probabilistic sampling ; San Francisco Estuary ; coast ; Pseudomonas ; Shewanella algae ; Vibrio parahaemolyticus ; biocide ; Listeria monocytogenes ; biofilm ; planktonic culture ; pulsed-field gel electrophoresis ; Escherichia coli ; fosfomycin ; nitrofurantoin ; antimicrobial resistance ; antibiotic susceptibility ; WGS ; phylogenetic analysis ; DNA mismatch repair system ; Salmonella Choleraesuis ; Iberian pig ; wild boar ; phylogenetic relationship ; plasmid replicon typing ; colistin ; carcass ; cfr gene ; fexA gene ; linezolid ; mutation ; pig ; public health ; S. aureus ; avian colibacillosis ; salmonellosis ; MDR ; tetA ; nisin ; mutant prevention concentration ; mutant selection window ; antimicrobial susceptibility testing ; horizontal gene transfer ; Salmonella ; reptiles ; isolation ; biofilms ; chlorhexidine gluconate ; wounds ; Gram-negative bacteria ; colonization ; infection ; clonal lineages ; resistance genes ; virulence factors ; Staphylococcus aureus ; skin and soft-tissue infections ; plasmids ; Panton–Valentine leucocidin ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSG Microbiology (non-medical)
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.
    Keywords: QH301-705.5 ; Q1-390 ; thermodynamic modeling ; molecular dynamics simulation ; poorly soluble drugs ; amorphous solid dispersions ; dissolution enhancement ; crystallization tendency ; continuous processing ; stability ; milling ; granulation ; thermal analysis ; amorphous ; ball milling ; pharmaceutical glass ; dissolution ; rebamipide ; poloxamer ; classification ; polyelectrolytes ; amorphisation ; self-assembly ; dissolution rate ; miscibility ; bioavailability ; solubility ; evaporation ; mesoporous ; polyelectrolyte excipient matrix ; polymer ; bicaludamide ; phase diagram ; Weibull dissolution model ; spectroscopic techniques ; anticancer drugs ; manufacturing methods ; nucleation ; molecular complex ; nanoaggregates ; enrofloxacin ; accelerated stability test ; solubility enhancement ; amorphous solid dispersion ; tadalafil ; process development ; amorphous polymeric salt ; Wood’s apparatus ; hot melt extrusion ; solid dispersions ; intrinsic dissolution rate ; solid dispersion ; interaction ; crystallization ; spray drying ; characterization ; ciprofloxacin ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: The plant kingdom, with its terrestrial and marine natural products, has been widely explored. Plant-based products have long been used to prevent and treat various ailments. Many natural compounds have been reported to have a variety of interesting and significant biological activities, including antioxidant, anti-inflammatory, antitumor, antibacterial, antiviral, antifungal, antiparasitic, analgesic, antidiabetic, anti-atherogenic, and antiproliferative, as well as cardioprotective and neuroprotective properties. Therefore, researchers pay special attention to the bioactive compounds synthesized by plants. Opportunities in functional ingredients and treatment of NCDs (oxidative stress, diabetes, obesity, metabolic syndrome, etc.) are widely explored. However, many therapeutic properties of plants are still to be discovered. This Special Issue reprint intends to substantially contribute to our knowledge of their beneficial properties. Natural products could be a vast resource in respect of human well-being improvement. This Special Issue reprint also aims to disseminate some of the most recent and significant contributions in natural product research on phytochemicals and biological activity.
    Keywords: Sempervivum tectorum L. ; mineral content ; bioavailable fraction ; heavy metals ; open-field plants ; tissue culture plants ; in vitro callus culture ; Rubus subg. Rubus Watson ; Vaccinium corymbosum L. ; phenolics ; radical scavenging activities ; ferric reducing power ; waste peel ; essential oil ; GC-MS ; volatile compounds ; antimicrobial activity ; chemical composition ; antioxidant activity ; fluorescence ; total phenolic content ; Aspergillus flavus ; maize ; peel extracts ; AFB1 ; qRT-PCR ; Opuntia spp. ; phytochemicals ; biological activities ; antioxidant capacity ; chemopreventive effect ; integrated pest management ; Oriental fruit fly ; pomology ; post-harvest disease control ; Sambucus nigra L. ; medicinal plants ; flavonoids ; phenols ; carbohydrates ; amino acids ; Flos Abelmoschus manihot ; medicinal part ; non-medicinal parts ; UFLC-Triple TOF-MS/MS ; metabolite profiling ; multivariate statistical analysis ; juniper ; natural products ; tree ; leaves ; disease ; bioactive compounds ; microbial resistance ; turmeric ; Curcuma aromatica ; Curcuma caesia ; Curcuma longa ; Curcuma zanthorrhiza ; enantiomeric distribution ; chiral ; cultivars ; foliar sprays ; Humulus lupulus ; liming ; phenolic compounds ; plant vigour ; polyphenols ; antimicrobial activity enhancement ; ascorbic acid ; Maillard reaction products ; laccase–mediator system ; horseradish peroxidase–H2O2 system ; tomato pomace ; by-product utilization ; finger millet ; gluten-free ; potato flour ; convenience food ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: This Proceedings reprint comprises a collection of the papers presented at the second International Conference on Computational Engineering and Intelligent Systems, held online in the period 18–20 November 2022. The conference focused on computational engineering including modeling, simulation, analysis, and intelligent systems driven by computing and artificial intelligence. The papers included in this collection deal with a range of topics including smart grids, renewable energies, intelligent safety and control systems, power quality and cloud computing.
    Keywords: Computational Engineering ; Intelligent systems ; Optimization ; Artificial Intelligence ; &nbsp ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint compiles several studies on radiation interactions with biomolecules. The fragmentation induced by slow electron and electron scattering processes are described, and the induced processes by UV radiation are characterised. The present Special Issue offers complementary studies on radiation induced by photons and electrons in biological (and related) target molecules. The present collection provides important insights on radiation physics and chemistry and the advances in knowledge in these areas.
    Keywords: methane ; cross-section ; elastic scattering ; electrons ; CRISPR/Cas9 ; DNA cleavage ; ECD ; spectroscopy ; guide RNA ; RNP complex ; SpCas9 ; radiosensitizer ; low-energy electron ; dissociative electron attachment ; roaming ; tirapazamine ; predissociation ; electron scattering cross sections ; benzene ionization ; VUV photoabsorption ; halopyrimidines ; valence and Rydberg states ; time-dependent density functional theory ; radiosensitizers ; taurine ; elastic constant ; Brillouin scattering ; acoustic mode ; negative ions ; oxaloacetic acid ; citric acid ; mass spectrometry ; anticancer drugs ; cisplatin ; platinum (II) halo-carbonyl complexes ; low-energy electrons ; dissociative ionization ; focused electron beam induced deposition ; sevoflurane ; pheomelanin ; nitrotyrosine ; dityrosine ; photooxidation ; photosensitizer ; IR radiation ; horseradish peroxidase ; catalase ; alkaline phosphatase ; antioxidant ; vapor ; coherent domain ; anion–molecule collisions ; electron detachment cross sections ; positive ion-induced fragmentation ; molecular dynamics ; radiotherapy ; X-ray ; modified nucleosides ; DNA damage ; hypoxia ; chemoradiation ; low-energy electron interaction ; perfluorination ; HF formation ; pentafluorothiophenol ; 2-fluorothiophenol ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSG Microbiology (non-medical)
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Agricultural production management is facing a new era of intelligence and automation. With developments in sensor technologies, the temporal, spectral, and spatial resolution from ground/air/space platforms have been notably improved. Optical sensors play an essential role in agriculture production management. Specifically, monitoring plant health, growth conditions, and insect infestation has traditionally involved extensive fieldwork. We believe that sensors, artificial intelligence, and machine learning are not simply scientific experiments but opportunities to make our agricultural production management more efficient and cost-effective, further contributing to the healthy development of natural–human systems. This reprint compiles the latest research on optical sensors and machine learning in agricultural monitoring, including related topics: Machine learning approaches for crop health, growth, and yield monitoring; Combined multisource/multi-sensor data to improve the crop parameters mapping; Crop-related growth models, artificial intelligence models, algorithms, and precision management; Farmland environmental monitoring and management; Ground, air, and space platforms application in precision agriculture; Development and application of field robotics; High-throughput field information survey; Phenological monitoring.
    Keywords: soil moisture content ; spectral processing technology ; hyperspectral ; principal component analysis ; feature parameters extraction ; yield estimation ; rice ; unmanned aerial vehicle (UAV) ; tasseled cap transformation ; precision agriculture ; weed identification ; YOLOv4-Tiny ; attention mechanism ; multiscale detection ; angle normalization ; vegetation canopy reflectance ; geostationary satellite ; path length correction ; Minnaert model ; GOCI ; winter wheat ; LSTM ; LAI ; deep learning ; land use ; land cover ; classification ; random forest ; Sentinel data ; SRTM ; feature selection ; accuracy ; validation ; unmanned aerial vehicle ; soybean ; convolutional neural network ; multispectral imagery ; fusarium head blight ; texture indices ; machine learning ; cropland ; multi-seasonal ; fractal feature ; feature extraction ; accuracy evaluation ; black soil ; UAV ; chlorophyll ; fractional vegetation cover ; maturity monitoring ; anomaly detection ; smart agriculture ; detection of apple leaf diseases ; YOLOv5 ; transformer ; CBAM ; crop type classification ; multi-temporal ; remote sensing ; dairy cows ; body condition score ; 3D TOF sensor ; non-contact evaluation ; recognize area of interest ; sugarcane clones ; canopy cover ; light interception ; biomass ; cane yield ; peanut southern blight ; reflection spectrum ; spectral index ; continuous wavelet transform ; VGNet ; corn diseases ; leaf detection ; lightweight ; transfer learning ; agriculture ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Rivers have been intensively degraded due to increasing anthropogenic impacts from a growing population in a continuously developing world. Accordingly, most rivers suffer from pressures as a result of increasing dam and weir construction, habitat degradation, flow regulation, water pollution/abstraction, and the spread of invasive species. Science-based knowledge regarding solutions to counteract the effects of river degradation, and melding principles of aquatic ecology and engineering hydraulics, is thus urgently needed to guide present and future river restoration actions. This Special Issue gathers a coherent set of studies from different geographic contexts, on fundamental and applied research regarding the integration of ecohydraulics in river restoration, ranging from field studies to laboratory experiments that can be applied to real-world challenges. It contains 13 original papers covering ecohydraulic issues such as river restoration technologies, sustainable hydropower, fish passage designs and operational criteria, and habitat modeling. All papers were reviewed by international experts in ecology, hydraulics, aquatic biology, engineering, geomorphology, and hydrology. The papers herein well represent the wide applicability of ecohydraulics in river restoration and serve as a basis to improve current knowledge and management and to reduce arguments between different interests and opinions.
    Keywords: QH301-705.5 ; Q1-390 ; Fish passage and migration ; Prioritization of river connectivity for sustainable fisheries ; Sustainable hydropower ; Spawning grounds ; Invasive species management ; Environmental flows ; Habitat modeling ; Dam/weir retrofitting and removal ; Riparian and aquatic vegetation dynamics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Cement and lime currently are the most common binders in building materials. However, alternative materials and methods are needed to overcome the functional limitations and environmental footprint of conventional products. This Special Issue dedicated to “New frontiers in cementitious and lime-based materials and composites” gathers selected reviews and experimental articles that showcase the most recent trends in this multidisciplinary field. Authoritative contributions from all around the world provide important insights into all areas of research related to cementitious and lime-based materials and composites, spanning from structural engineering to geotechnics, including materials science and processing technology. This Topical Collection is intended to foster innovation and help researchers and developers to identify new solutions for a more sustainable and functional built environment.
    Keywords: durability ; hardened properties ; green composite ; fresh properties ; recycled concrete aggregates ; natural coarse aggregates ; enzyme-induced calcite precipitation ; microbial-induced calcite precipitation ; geotechnical engineering ; geoenvironmental engineering ; precast concrete wall ; interfacial bonding strength ; joint concrete ; interface processing ; washed rough surface ; roughness ; storage time ; cement mortar ; End-of-Life Tyre ; waste ; surface treatment ; compressive strength ; flexural strength ; workability ; fly ash ; freezing shaft sinking ; shaft lining structure ; uneven pressure ; hybrid fiber-reinforced concrete ; crack ; autogenous self-healing ; curing conditions ; supplementary cementitious materials (SCMs) ; GRC-PC ; integrated wall panels ; composite method ; shrinkage properties ; dissipation energy density ; high-strength concrete ; Weibull distribution ; damage mechanics ; constitutive model ; repeated impact ; ACI 544-2R ; high temperatures ; fire ; residual strength ; lime-cement mortar ; air-entrained agent ; heritage conservation ; reconstruction and restoration of historical buildings ; properties ; mechanical ; electrical resistivity ; ecofriendly ternary concrete ; SCBA ; SF ; coastal cemented soil ; nano silica ; iron tailings ; mechanical properties ; microscopic mechanism ; granite dust ; stabilizer ; particle size ; plasticity ; unconfined compression strength ; cement ; lime ; sustainable materials ; fibre-reinforced composite ; recycled aggregates ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level.
    Keywords: QH301-705.5 ; genome stability ; Trisomies ; microtubule dynamics ; Checkpoints ; Inheritance ; Cell division ; centrosome ; Down Syndrome ; Cell motility ; Cell regulation ; chromosome segregation ; Microtubules ; Cell cycle ; kinetochore ; Cytoskeleton ; Cell reproduction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: Glycosaminoglycans are linear, anionic polysaccharides (GAGs) consisting of repeating disaccharides. GAGs are ubiquitously localized throughout the extracellular matrix (ECM) and to the cell membranes of cells in all tissues. They are either conjugated to protein cores in the form of proteoglycans, e.g., chondroitin/dermatan sulfate (CS/DS), heparin/heparan sulfate (Hep/HS) and keratan sulfate (KS), as well as non-sulfated hyaluronan (HA). By modulating biological signaling GAGs participate in the regulation of homeostasis and also participate in disease progression. The book, entitled “Exploring the multifaceted roles of glycosaminoglycans (GAGs)—new advances and further challenges”, features original research and review articles. These articles cover several GAG-related timely topics in structural biology and imaging; morphogenesis, cancer, and other disease therapy and drug developments; tissue engineering; and metabolic engineering. This book also includes an article illustrating how metabolic engineering can be used to create the novel chondroitin-like polysaccharide.A prerequisite for communicating in any discipline and across disciplines is familiarity with the appropriate terminology. Several nomenclature rules exist in the field of biochemistry. The historical description of GAGs follows IUPAC and IUB nomenclature. New structural depictions such as the structural nomenclature for glycan and their translation into machine-readable formats have opened the route for cross-references with popular bioinformatics resources and further connections with other exciting “omics” fields.
    Keywords: GAGs: ; Hyaluronic ; Acid, ; Heparan ; (Sulfate) ; Heparin, ; Heparosan ; Chondroitin ; Dermatan ; Keratan, ; GAGs ; like ; Peri ; and ; Extracellular ; Matrix ; Regulation ; &amp ; Biosynthesis ; of ; GAG ; Extraction ; Synthesis ; (chemical, ; metabolic ; engineering,...) ; Characterization ; sequence ; molecular ; weight, ; degree ; polymerization, ; 3D ; structures,....) ; structure/properties ; relationships ; oligosaccharides ; Glycobiology ; structure/function ; relationship ; Protein-GAG ; complexes ; in ; disease ; GAG-based ; biomaterials ; as ; nanocarriers ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Exceptional loads on buildings and structures are known to take origin and manifest from different causes, like natural hazards and possible high-strain dynamic effects, human-made attacks and impact issues for load-bearing components, possible accidents, and even unfavorable/extreme operational conditions. All these aspects can be critical for specific structural typologies and/or materials that are particularly sensitive to external conditions. In this regard, dedicated analysis methods and performance indicators are required for the design and maintenance under the expected lifetime. Typical issues and challenges can find huge efforts and clarification in research studies, which are able to address with experiments and/or numerical analyses the expected performance and capacity of a given structural system, with respect to demands. Accordingly, especially for existing structures or strategic buildings, the need for retrofit or mitigation of adverse effects suggests the definition of optimal and safe use of innovative materials, techniques, and procedures. This Special Issue follows the first successful edition and confirms the need of continuous research efforts in support of building design under extreme loads, with a list of original research papers focused on various key aspects of structural performance assessment for buildings and systems under exceptional design actions and operational conditions.
    Keywords: blast loads ; slab-column joints ; prediction model ; damage level ; progressive collapse ; steel beam-to-column connections ; catenary mechanism ; double-span assemblies ; stiffness degradation ; timber-to-timber composite (TCC) joints ; push-out (PO) test setup ; inclined self-tapping screws (STSs) ; finite-element (FE) method ; cohesive zone modelling (CZM) method ; boundaries ; friction ; sensitivity study ; prototype abutment ; non-destructive test ; surcharge load ; mode number ; scour ; steel truss ; roof structure ; partial collapse ; finite element analysis ; lightning strike ; cable-stayed bridge ; social disaster ; blast scenario ; blast analysis ; LS-DYNA ; balau wood ; cross-arm ; transmission tower ; bracing system ; creep ; findley’s power law model ; burger model ; top-seat angle connections (TSACW) ; component-based models ; initial stiffness ; ultimate moment capacity ; moment-rotation relation ; artificial neural network (ANN) ; sensitivity analysis (SA) ; reinforced concrete column ; multi-column pier ; seismic behavior ; lap-splice ; transverse reinforcement ; plastic hinge ; ductility ; bonded-in rod (BiR) connections ; adhesives ; fracture modes ; moisture ; experiments ; linear elastic fracture mechanics (LEFM) ; analytical model ; aeroelastic experiments ; experimental uncertainty ; singular value decomposition ; correlation field ; cathedral ; foundation rehabilitation ; jacked-in piles ; soil injection ; cracks ; masonry ; differential equation of motion ; Legendre–Galerkin matrix (LGM) method ; algebraic polynomials ; single degree of freedom (SDOF) ; multi degree of freedom (MDOF) ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: A disease model displays pathological processes observed in human or animal diseases. The models are fundamental tools in biomedical research, and they are invaluable for providing new insights into mechanisms underlying organ function, establishing the pathophysiology of a disease, and testing potential therapeutic approaches.Models have been long used to study several diseases, including cardiovascular, oncologic, metabolic, infectious, and neurological diseases, among others. Animals or cells displaying pathological processes observed in human or animal diseases have been used as models. Moreover, mathematical models are also of great importance to disease modeling. Animal models offer the unique opportunity to investigate the function of genes and pathways and the in vivo effects of drugs, bridging the gap between basic science and the treatment of diseases. The selection of a suitable model system is a crucial step in research design. For disease modeling to be meaningful, a relevant cellular or genetic phenotype must be observed. Without the use of models, both research and clinical practice worldwide would be vastly different today.This Special Issue aimed to publish original research works or reviews with models of disease, highlighting their importance to search for new therapeutic strategies.
    Keywords: spontaneous models ; induced models ; genetically engineered models ; acute kidney injury ; biomarkers ; coagulation ; ischemia-reperfusion injury ; shock ; newborn lamb ; multiple intestinal loop model ; 3R ; Cryptosporidium parvum ; yeast cell wall fractions ; fatty liver disease ; glucose ; imipramine ; insulin ; obesity ; renal impairment ; retinal injury ; xenograft ; ectopic ; orthotopic ; hIBC ; cIMC ; whole-body ischemia ; cardiopulmonary resuscitation ; drug-induced hypothermia ; spinal motor neuron ; inflammation ; paraplegia ; virucidal drugs ; IBV ; chickens ; Coronaviridae ; silver nanoparticles ; artificial ribonuclease ; monoglyceride lauryl acid ; spinal cord hemisection ; Macaca radiata ; predegenerated nerve transplantation ; locomotor recovery ; Cornu Ammonis 1 ; glutaminergic synapse ; memory function ; oligodendrocyte ; pyramidal cells ; animal model ; trichotillomania ; hair-pulling ; body-focused repetitive disorder ; transitional cell carcinoma ; urothelial carcinoma ; histology ; therapeutic marker ; prognosis ; mandibular growth ; mandibular posterior displacement ; mandibular length ; condylar growth ; rat ; class III malocclusion ; orthodontic treatment ; antebrachial growth deformity ; dog ; osteotomy ; patient-specific instrumentation ; 3-D ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: Electrical machines are one of the most important components of the industrial world. They are at the heart of the new industrial revolution, brought forth by the development of electromobility and renewable energy systems. Electric motors must meet the most stringent requirements of reliability, availability, and high efficiency in order, among other things, to match the useful lifetime of power electronics in complex system applications and compete in the market under ever-increasing pressure to deliver the highest performance criteria. Today, thanks to the application of highly efficient numerical algorithms running on high-performance computers, it is possible to design electric machines and very complex drive systems faster and at a lower cost. At the same time, progress in the field of material science and technology enables the development of increasingly complex motor designs and topologies. The purpose of this Special Issue is to contribute to this development of electric machines. The publication of this collection of scientific articles, dedicated to the topic of electric machine design and application, contributes to the dissemination of the above information among professionals dealing with electrical machines.
    Keywords: electric AWD tractor ; SOC level ; simulation model ; load measurement system ; driving test ; brushless direct current motor with permanent magnet (BLDCM) ; winding configurations ; star ; delta ; star–delta ; fault states ; open circuit (OC) ; FFT ; neutral-point voltage ; electrical machine ; hydro generator ; faulty synchronization ; finite element method ; field-circuit modeling ; permanent magnet machines ; hybrid excitation ; electric vehicles ; wind power generator ; finite element methods ; variable speed machines ; synchronous generator ; permanent magnets ; demagnetization ; motor control ; switched reluctance motor ; MATLAB ; simulation ; wheel hub motor ; electric drive ; permanent magnet synchronous motor ; electrical machines ; thermal modeling ; preformed coils ; insulation systems ; pre-shaped conductor ; system model ; structural dynamics ; multibody simulation ; transient electrical machine model ; permanent magnet synchronous machine ; induction machine ; dynamic gear forces ; planetary gear ; synchronous condenser ; different materials ; magnetic flux leakage in the end ; eddy current loss ; fluid–solid coupling ; finite element analysis (FEA) ; interior PM synchronous motor ; surface PM synchronous motor ; traction applications ; finite element analysis ; flux switching machine ; flux bridge ; magnetic flux leakage ; variable flux machine ; axial flux generator ; spatial harmonic interaction ; harmonic balance method ; turbo-generator ; eddy current losses ; data driven ; support vector regression ; multi-layer perceptron ; vane pump ; electric motor ; integrated motor-pump assembly (IMPA) ; balanced vane pump ; fluid power drives ; brushless DC electric motor ; permanent magnet machine ; measurements ; high-speed motor ; electromagnetic analysis ; mechanical analysis ; thermal analysis ; electromechanical convertor ; drive system component ; electromagnetic calculation ; MR fluids ; MR multi-disc clutch ; clutch design ; electric train ; hybrid excited linear flux switching machine ; rope-less elevator ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: This Special Issue was intended to contribute to the sustainable mobility agenda through enhanced scientific and multi-disciplinary knowledge to investigate concerns and real possibilities in the achievement of a greener mobility and to support the debate between industry and academic researchers, providing an interesting overview on new needs and investigation topics required for future developments.
    Keywords: digging trajectory ; cable shovel ; robotic excavation ; multi-objective genetic algorithm ; electric vehicle ; propulsion cooling system ; modularity ; thermal management ; control optimization ; driving cycle ; energy consumption ; Markov chains ; driving range ; electrification ; green mobility ; compact off-highway vehicles ; battery electric ; urban air mobility ; WTW emissions ; hybrid electric vehicles ; battery aging ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 78
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This reprint is mainly aimed at economists involved in the energy market. Energy market processes have an enormous impact on people's day-to-day economic activities. The economics of sustainability leads the way in theorizing how best to prevent environmental degradation whilst also fostering positive economic development. For these reasons, the focus of this reprint is mainly on pollution and the energy transition. Works on energy resources and future-oriented solutions that reduce the consumption of classical energy resources are explored in the reprint. Papers relating to contemporary accounting and the stock market are also presented. The geographical area of the works showcased here essentially covers the entire eastern hemisphere of the globe (Asia, Africa and Europe). They are mainly empirical studies, although in one case a bibliometric analysis is included.
    Keywords: energy market ; stock market ; mood ; emotions ; weather ; causality ; industry ; renewable energy ; CO2 emissions ; Sub-Saharan Africa ; pollution charges ; green technology innovation ; industrial enterprise ; heterogeneity analysis ; oil prices ; inflation ; exchange rate ; goodwill ; impairment of goodwill ; quality of financial statements ; energy sector ; mining ; fuel ; disclosures of financial information ; nearly zero-energy housing ; NZEB ; barriers ; perceptions ; housing professionals ; sustainability transition ; energy ; green indicators ; blue indicators ; carbon neutrality ; nonlinear ARDL ; European Union ; sustainable energy development ; energy transformation ; energy strategy ; taxonomical analysis ; ranking ; TOPSIS method ; renewable energy transition ; non-euro area ; panel data ; Granger causality ; VECM ; human capital ; CO2 emission ; FDI ; technological innovation ; carbon emission efficiency ; carbon emission ; renewable energy sources ; government regulations ; subsidy programmes ; prosumers ; micro-installations ; regression discontinuity design ; green taxes ; greenhouse gas emissions ; indicators of reduction in greenhouse gas emissions ; sustainable development ; green energy ; innovation ; trends ; bibliometric analysis ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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  • 79
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Dear Colleagues, When Hayflick and Moorhead coined the term “cellular senescence” (CS) almost 60 years ago, this phenomenon was understood as a mechanism, usually induced by activation of the DNA-repair machinery, to prevent uncontrolled proliferation. Meanwhile, additional beneficial roles for CS have been identified, such as embryonic development and wound healing. The senescence associated secretory phenotype (SASP) activated in most senescent cells (SC) signals to the immune system “come here and remove me”. In organisms with young and functional immune systems, occurring SC are usually detected and removed. If SC remain in the tissue expressing the SASP, this will cause not just a damaging local inflammation but can also induce remodeling and regeneration of the surrounding tissue as well as spreading of senescence. Old organisms show reduced regenerative potential and immune function which leads to accumulation of SC. Accordingly, accumulation of SC was observed in tissues of aged individuals, but importantly also in the context of age-related disorders, neurodegenerative, or cardiovascular diseases and others. Because of its detrimental effect of the surrounding tissue, accumulation of SC is not just a consequence, but can rather been understood as a major driver of aging. In line with this, recent studies described that removal of SC showed beneficial effects on healthspan and lifespan. This exciting research led to the discovery of “senolytics”, drugs which can kill SC. Given the heterogeneity of cell types that show senescence-like phenotypes, including heart muscle and post-mitotic neuronal cells, further research is required to unravel the molecular background that renders a cell type vulnerable to senesce. Additionally, it will be important to understand how senescence is cell type-specifically induced and which molecules serve as drug targets to prevent senescence and its spreading, or actively kill SC. This special issue will shed light on the molecular pathways of CS and inflammaging and on possible strategies to interfere with these processes. Dr. Markus Riessland Guest Editor
    Keywords: γH2AX ; Alzheimer’s disease ; DNA damage ; mild cognitive impairment ; senescence ; secreted protein acidic and rich in cysteine ; regeneration ; homeostasis ; cellular senescence ; biology of aging ; neurodegeneration ; brain ; geroscience ; senolytics ; tauopathy ; cancer ; stress response ; post-mitotic ; neuronal senescence ; amyotrophic lateral sclerosis ; senescence-associated secretory phenotype (SASP) ; cell-cycle ; melanoma ; pancreatic adenocarcinoma ; tumor infiltration ; chemotherapy resistance ; prostate ; inflammation ; AIM2 inflammasome ; POP3 ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: This reprint aims to collect state-of-the-art research contributions that address challenges in the emerging 5G networks design, dimensioning and optimization. Designing, dimensioning and optimization of communication networks resources and services have been an inseparable part of telecom network development. The latter must convey a large volume of traffic, providing service to traffic streams with highly differentiated requirements in terms of bit-rate and service time, required quality of service and quality of experience parameters. Such a communication infrastructure presents many important challenges, such as the study of necessary multi-layer cooperation, new protocols, performance evaluation of different network parts, low layer network design, network management and security issues, and new technologies in general, which will be discussed in this book.
    Keywords: bit error rate (BER) ; space-time coding (STC) ; Singular Value Decomposition (SVD) ; massive MIMO ; orthogonal transform division multiplexing (OTDM) ; Toeplitz matrix ; 5G networks ; BBU centralization ; cloud radio access networks ; eCPRI ; fronthaul ; filter bank multicarrier ; isotropic orthogonal transfer algorithm ; intrinsic interference ; Co-time Co-frequency Full Duplex (CCFD) ; self-interference (SI) signal cancellation ; RF domain ; optimize Least Mean Square (LMS) algorithm ; interference cancellation ratio (ICR) ; 5G core network slice ; network slicing ; resource attributes ; slice provisioning ; topology attributes ; beamforming ; interference management ; throughput ; fairness index, small cell networks ; OFDM ; congestion ; random ; quasi-random ; recursive ; restricted ; reservation ; complete sharing ; D2D communication ; 5G IoT network ; lightweight cryptography ; authentication ; midhaul ; radio-over-fiber ; optical gNB-DU ; RRH ; A-RoF ; D-RoF ; BBU ; all-optical network ; handover ; HetNets ; mobility management ; self-optimization ; spectrum handoff ; spectrum sensing ; cognitive radio networks ; cognitive radio user ; primary and secondary user ; 5G mobile communication network ; multi-access edge computing ; centralized cloud computing ; hybrid cloud computing ; Palm-Jacobaeus loss formula ; blocking probability ; multi-service traffic ; separated resources ; performance evaluation ; cellular systems ; channel emulator ; non-stationary MIMO channel ; discrete channel model ; field-programmable gate array (FPGA) platform ; Cloud Radio Access Network (C-RAN) ; Microwave Radio Transmission (MRT) ; Free Space Optics (FSO) ; Fiber Optics (FO) ; multi-agent systems ; laplacian eigenvalues ; augmented Lagrange based Alternating Direction Inexact Newton (ALADIN) method ; consensus algorithms ; Alternating Direction of Multipliers Method (ADMM) ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 81
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: This book focuses on fundamental and applied research on construction project management. It presents research papers and practice-oriented papers. The execution of construction projects is specific and particularly difficult because each implementation is a unique, complex, and dynamic process that consists of several or more subprocesses that are related to each other, in which various aspects of the investment process participate. Therefore, there is still a vital need to study, research, and conclude the engineering technology and management applied in construction projects. This book present unanimous research approach is a result of many years of studies, conducted by 35 well experienced authors. The common subject of research concerns the development of methods and tools for modeling multi-criteria processes in construction engineering.
    Keywords: earned value method—EVM ; time variances ; cost variances ; schedule ; cadastre ; land surveyor ; construction surveying ; building layout ; polar coordinates ; stake-out methods ; total station ; construction reports ; construction contracts ; natural language processing ; machine learning ; simulation modeling ; bridge expansion and contraction installation (BECI) ; decision making (DM) ; technical condition assessment ; analytic hierarchy process (AHP) ; whale optimization algorithm ; Tent chaotic mapping ; Lévy flight ; resilience ; baseline schedule ; uncertainty ; taxonomy ; construction project ; PERT ; theory of constraint (TOC) ; drum-buffer-rope (DBR) ; construction schedule ; monitoring progress ; construction phase ; automated monitoring ; digital tools ; as-built ; as-planned ; efficiency ; risk ; randomization ; association analysis ; tabu search ; delay ; time schedules ; project risk ; construction project management ; Time-at-Risk (TaR) ; investment-construction process model ; Monte Carlo simulation ; decision-making process ; decision modelling in construction activities ; decisions in civil engineering ; liquid cooling system ; flow calibration ; differential pressure ; experimental method ; aircraft ; building information modelling (BIM) ; automatisation ; facilities design ; domestic plumbing and sanitation ; management ; project cost ; investment schedule ; risk mitigation ; randomness ; fuzziness ; health and safety control ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This Special Issue explores empirical studies of emotional mechanisms, qualitative and quantitative measurements of emotion, the recognition of emotional contexts, and the application of emotion. We introduce fourteen papers, ranging from lab-based studies aimed at understanding emotional mechanisms to applying emotion recognition in the real world (e.g., in driving, games, education, and virtual avatars). This Special Issue explores empirical studies of emotional mechanisms, qualitative and quantitative measurements of emotion, the recognition of emotional contexts, and the application of emotion. We introduce fourteen papers, ranging from lab-based studies aimed at understanding emotional mechanisms to applying emotion recognition in the real world (e.g., in driving, games, education, and virtual avatars).
    Keywords: speech emotion recognition ; domain adaptation ; SER generalization ; Korean Emotional Speech Database ; ensemble model ; multi-path ; group-loss ; BLSTM network ; facial micromovement ; emotion recognition ; emotion authenticity ; HRV parameter ; game addiction ; League of Legends ; stress response ; sensitivity ; specificity ; logistic regression ; facial action unit ; facial aging ; facial expression ; posed emotion ; virtual avatar ; virtual human ; virtual character ; embodied conversational agent ; social interaction ; empathy ; CNN ; cognitive workload ; functional connectivity analysis ; LSTM ; mental workload ; mutual information ; phase locking value ; phase transfer entropy ; deep learning ; facial expression recognition (FER) ; 3D convolutional neural network (3D CNN) ; multirate signal processing ; minimum overlapped frame structure ; self-attention ; multi-depth network ; video content empathy ; micro-movement synchronization ; non-contact empathy measurement ; empathic advertisement ; multimodal affective computing ; catecholamines ; emotion classification ; wearable devices ; deep neural networks ; multispectral imaging ; face recognition ; in the wild ; driver emotion recognition ; multimodal ; self-report ; real-world driving ; EEG ; learning emotions ; attention ; convolutional neural network ; multi-channel band features ; eye movement ; brain connectivity ; review ; human emotions ; affective and physiological states ; Plutchik’s wheel of emotions ; sensors ; methods and applications ; statistical and multiple criteria analysis ; country success and publications maps of the world ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Civil engineering structures may vibrate due to different sources of excitations such as earthquakes, wind, traffic, humans, etc. The resulting vibrations may not be acceptable from the perspective of vibration comfort or can even impair the structure's safety. Depending on the excitation mechanism, anti-vibration measures range from increasing the structural damping using local dampers, decoupling the structure from the disturbance using vibration isolators and compensating for the excitation forces using vibration compensators. The Special Issue "Efficient Damping and Isolation Systems for Civil Structures" presents some of the recent advances in the associated fields of research and development.
    Keywords: isolation ; high damping rubber bearing ; low shape factor ; performance test ; experiment ; three-dimensional (3D) seismic isolation ; vertical seismic isolation device ; disc spring ; helical coil spring ; steel damper ; laminated rubber bearing ; seismic energy dissipation ; nuclear power plant equipment ; seismic isolation frequency ; hysteretic behavior ; cable ; control ; damping ; semi-active ; negative stiffness ; vibration ; liquid storage tank ; MetaFoundation ; time domain analysis ; earthquake ; passive control ; stop band ; suspended ceiling systems ; passively controlled structure ; pulley tackle mechanism ; shake table test ; simulation analysis ; tower-like structures ; tuned liquid gas damper ; elastic membrane ; gas spring ; gas volume ; SA-TLGD ; TLCGD ; TLCD ; TMD ; inerter ; optimization ; TMDI ; vibration mitigation ; tuned sloshing damper ; TSD ; tuned mass damper ; numerical simulation ; coupled simulation ; computational wind engineering ; CWE ; hysteresis ; internal resonances ; nonlinear modal interaction ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: This reprint includes contributions from leaders in the field of personalized medicine in ophthalmology. The contributions are diverse and cover pre-clinical and clinical topics. We hope you enjoy reading the articles.
    Keywords: subthreshold micropulse laser ; 577-nm laser ; laser fixed parameters ; diabetic retinopathy ; diabetic macular edema ; optical coherence tomography ; autofluorescence ; real-life ; diabetic macular oedema ; visual prognosis ; indicators ; personalized medicine ; age-related macular degeneration ; choroidal neovascularization ; classification ; machine learning ; type 2 diabetes ; retinopathy ; ethnicity ; general practice ; risk factors ; progression ; glycemic gap ; glucose variability ; ETDRS classification ; biomarkers ; phenotypes ; anti-vascular endothelial growth factor ; diabetic retinopathy severity scale ; panretinal leakage index ; neovascular age-related macular degeneration ; anti-VEGF therapy ; retinal thickness ; visual acuity ; variability ; leakage index ; microaneurysms ; intravitreal aflibercept ; neovascularization ; ultra-widefield fluorescein angiography ; retinal imaging ; quantitative biomarkers ; precision medicine ; autoantibodies ; AT1-receptor ; PAR1 ; VEGF-A ; VEGF-B ; VEGF-receptor 2 ; AMD ; complement system ; semi-quantitative multiplex profilin ; mass spectrometry ; C4 ; vitronectin ; factor I ; genetic variants ; metabolites ; HDL ; central area thickness ; biomarker ; microRNA ; anti-VEGF ; retina ; edema ; OCT ; tomography ; microphysiological systems ; blood-neural barriers ; neurovascular unit ; disease modeling ; 3D models ; organ-on-a-chip ; inner blood-retinal barrier ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 85
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-10-25
    Description: Patient outcomes remain poor for many cancers despite improvements in treatments and new molecular-targeted biomedicines for certain cancer types or subtypes. Dose-limiting toxicity, a narrow therapeutic index, and the development of resistance to traditional anti-cancer agents are well-established. It is apparent that inherent and acquired drug resistance are major challenges with molecular-targeted agents and that on- as well as off-target side effects can still occur. Other issues include drug metabolism by the body and safely supplying a sufficient amount of active drug to the tumor cells. There is a clear and urgent need for new molecular targets and drugs that specifically target cancer cells in different ways to existing approved drugs. This book, through a collection of eight research articles and two review articles from the Biomedicines themed Special Issue ‘Novel Anti-Cancer Agents and Cellular Targets and Their Mechanism(s) of Action’, provides a snapshot of some of the diverse and exciting research approaches being taken by the cancer research community in trying to address some of these therapeutic challenges.
    Keywords: microtubule acetylation ; triple-negative breast cancer ; anti-cancer agent ; apoptosis ; K562 ; 8-hydroxydaidzein ; autophagy ; BCR-ABL ; MAPK ; NF-κB ; c-myc ; RNA interference ; siRNA ; oncogene ; gene silencing ; expression ; nanosystems ; Cytochrome P450 ; CYP1A1 ; CYP1B1 ; CYP2W1 ; breast cancer ; prodrug ; bioprecursor ; duocarmycin ; phortress ; AQ4N ; 5-FU resistance ; colorectal cancer ; drug repurposing ; Genomics of Drug Sensitivity in Cancer ; Connectivity Map ; anticancer drug ; B-lactam steroid alkylators ; synthetic lethality ; poly (ADP-ribose) polymerase inhibitors ; ovarian cancer ; hybrid steroidal alkylating agents ; migration ; invasion ; glioblastoma ; CCN1 ; mesenchymal–amoeboid transition ; biomarker ; HepG2 ; Huh7 ; isatin sulfonamides ; angiogenesis ; cancer hallmarks ; molecular docking ; EGFR tyrosine kinase inhibitor ; photon upconversion ; triplet-triplet annihilation ; in vivo imaging ; PLGA ; nanoparticles ; affibody molecule ; human epidermal growth factor receptor 3 (HER3) ; BxPC-3 ; emtansine ; DM1 ; albumin binding domain ; affibody drug conjugate (AffiDC) ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 86
    Publication Date: 2024-04-05
    Description: Ranaviruses and other viruses within the family Iridoviridae, infect a wide range of ecologically and commercially important ectothermic vertebrates, i.e., bony fish, amphibians, and reptiles, and invertebrates, including agricultural and medical pests and cultured shrimp and crayfish, and are responsible for considerable morbidity and mortality. Understanding the impact of these various agents on diverse host species requires the combined efforts of ecologists, veterinarians, pathologists, comparative immunologists and molecular virologists. Unfortunately, investigators involved in these studies often work in discipline-specific silos that preclude interaction with others whose insights and approaches are required to comprehensively address problems related to ranavirus/iridovirus disease. Our intent here is to breakdown these silos and provide a forum where diverse researchers with a common interest in ranavirus/iridovirus biology can profitably interact. As a colleague once quipped, “Three people make a genius.” We are hoping to do something along those lines by presenting a collection of research articles dealing with issues of anti-viral immunity, identification of a potentially novel viral genus exemplified by erythrocytic necrosis virus, viral inhibition of innate immunity, identification of novel hosts for lymphocystivirus and invertebrate iridoviruses, and modelling studies of ranavirus transmission. Collectively these and others will exemplify the breadth of ongoing studies focused on this virus family.
    Keywords: QH301-705.5 ; Q1-390 ; risk assessment ; n/a ; CQIV ; mathematical models ; amphibian ; iridovirus ; ISDL ; Exopalaemon carinicauda ; viral load ; virus isolation ; European chub ; outbreak ; Unconventional T cell ; early detection ; susceptible species ; viral immune evasion ; DNA virus ; Rana grylio virus ; antibody ; intracellular localization ; Rana grylio virus (RGV) ; British Columbia ; Iridoviridae ; Andrias davidianus ranavirus ; viral infection ; susceptible-infected (SI) models ; yeast two-hybrid (Y2H) ; prevalence ; host-pathogen interactions ; Pacific herring ; Procambarus clarkii ; Bayesian inference ; eDNA ; amphibians ; Artemia spp. ; ranavirosis ; cross-species transmission ; FV3 ; SHIV ; Gryllus bimaculatus ; Pacific salmon ; NF-?B ; cricket ; IIV-6 ; virus binding ; erythrocytic necrosis virus (ENV) ; envelope protein ; iridovirus core proteins ; emerging infection ; host ; Ranavirus ; white head ; Rana temporaria ; Imd ; biosecurity ; antiviral immunity ; Decapodiridovirus ; endemic disease ; Macrobrachium rosenbergii ; co-immunoprecipitation (Co-IP) ; Common frog ; aquatic animals ; virus surveillance ; immunomodulators ; frog virus 3 ; ELISA ; DIV1 ; megalocytivirus ; Lymphocystis disease virus ; bearded dragon ; susceptibility ; protein interaction ; Pogona vitticeps ; viral erythrocytic necrosis (VEN) ; histopathology ; epidemiology ; native-fish conservation ; viral transmission ; Sparus aurata ; immunohistochemistry ; lizard ; disease dynamics ; immunofluorescence ; transmission modelling ; Macrobrachium nipponense ; interferon ; nonclassical MHC ; heparan sulfate ; ranavirus ; Mexico ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Myxobacteria are fascinating and important prokaryotes. They have large genomes and exhibit a wide range of interesting behaviors, including multicellular fruiting body formation, social interaction, predation, and secondary metabolite production. Substantial progress is being made in understanding their ecological roles and the evolutionary forces that have shaped their phenotypes and behaviors. Novel species of myxobacteria are regularly described, often producing unusual metabolites and enzymes which can be of significant biotechnological interest. Molecular studies, ranging in subject from individual enzymes to entire ‘omes, continue to provide rich insights into myxobacterial biology. This collected volume brings together five research articles and three reviews, to provide a snapshot of current myxobacterial research in all its diversity.
    Keywords: carotenoids ; comparative genomics ; development ; fruiting body formation ; one-component systems ; quorum signalling ; two-component systems ; myxobacteria ; Myxococcales ; germination ; bacterial cell wall ; sporulation ; morphology ; photoreceptor ; photosensitizer ; photoregulation ; singlet oxygen ; plasmalogens ; CarF ; vitamin B12 ; CarH ; ECF-sigma ; CarD-CdnL ; microbial food web ; trophic interactions ; predator–prey interactions ; mesopredator ; social bacteria ; nematodes ; experimental community ; behavior ; Myxococcus sp. ; Corallococcus sp. ; Melittangium sp. ; Archangium sp. ; biosynthetic gene clusters ; Myxococcus xanthus ; phase contrast microscopy ; fluorescence microscopy ; aggregation ; rippling ; deep learning ; generative adversarial network ; pretator-prey coevolution ; antagonism ; mucoidy ; predatory bacteria ; bacterial predation ; prey diversity ; negative frequency dependence ; experimental evolution ; MyxoEE-6 ; functional genomics ; genome evolution ; genome organisation ; pan-genome ; proteomics ; taxonomy ; transcriptomics ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSG Microbiology (non-medical)
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Land use is the projection of human activities in space, and it has become an important insight into the transformation and reconstruction of human society and economy. Rural land use in China is undergoing rapid transformation driven by the rapid development of science and technology. Effectively grasping the change and transformation process of rural land use and its internal mechanism provides an important reference for revealing the inherent laws of China's rural development. Rural land use is closely related to the rural vitalization strategy and urban–rural integration in the new era. An in-depth study of China's rural land use and policy reform provides the basis of knowledge for formulating and optimizing urban–rural relations. This Special Issue focuses on the changes, effects, and regulation of rural land use in China, focusing on its main contradictions and solutions, building a cooperative network and sharing platform for rural land use research from a multidisciplinary perspective, and further deepening the theoretical innovation and practical application of rural land use research. We invited scholars from various disciplines to contribute to the Special Issue, especially with papers on the subjects of theoretical innovation, technological innovation, and practical innovation in this field.
    Keywords: family farm ; efficiency ; DEA model ; Tobit model ; farm operation ; influencing factors ; soybean ; production pattern ; spatial agglomeration ; policy implications ; spatiotemporal changes ; crop planting structure ; black soil region ; Northeast China ; county-level ; geographic characteristics ; hollow village ; actor–network ; governance mode ; operation process ; appropriate tillage sand land ; land survey ; limiting factor ; land evaluation ; cultivated land protection ; Green Transition of Cultivated Land-use (GTCL) ; Water-Land-Food-Carbon (WLFC) ; coupling coordination ; land use change ; rural settlements ; spatial pattern evolution ; land policy ; China ; different modes ; land transfer ; livelihood capital ; difference-in-differences model ; Land Certificated Program (LCP) ; farmland “stickiness” ; land production function ; property rights ; agricultural policy ; cultivated land multifunctionality ; coupling coordination degree ; spatial-temporal pattern ; driving force ; major grain-producing areas ; northeast China ; comprehensive land consolidation ; pilot project ; decision-making evaluation ; farmers ; social investors ; non-agriculturalization rate ; ecological risk ; cultivated land change ; landform ; land management ; increasing versus decreasing balance (IVDB) ; balanced quota ; revenue ; inverted U-shaped curve ; Zhejiang province ; territorial space ; production–living–ecological space ; spatio-temporal variation ; eco-environment effect ; territorial spatial pattern ; eco-environmental quality ; soil contamination ; phytoremediation ; passivation ; farmer ; questionnaire survey ; paddy field ; dryland ; topographic gradient ; landscape characteristics ; land-use change ; rural settlement ; spatial distribution ; scale distribution ; morphological distribution ; the metropolitan fringe area ; Nanjing ; farmland transfer ; farmland function ; income structure ; rural household consumption ; consumption structure ; Yunnan Province ; farmers’ land transfer behavior ; herd effect ; geo-network ; the farmland right system reform ; creditor rights ; real rights ; agricultural modernization ; labor migration ; spatio-temporal evolution ; driving factor ; family structure ; heterogeneity ; area of land transfer ; rural–urban migration ; rural development ; land consolidation ; income distribution ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: In the past 20 years, karst desertification control has produced remarkable results, and the South China karst has been a global hotspot for greening. However, in the new stage of karst desertification control, the functional lag of forest ecosystems and the insufficient supply capacity of ecosystem services are gradually becoming prominent. We not only lack systematic research on vulnerability and resilience, structure and stability, ecological assets and services, carrying capacity and ecological security, and service trade-offs/synergies and optimization in controlled ecosystems. There is still a lack of research on the ecological processes of newly constructed forests in improving ecosystem functions and services. Therefore, this reprint mainly focuses on the research improvement of forest ecosystem functions in karst desertification control. This includes the improvement mechanism of ecosystem structure, function, and services, the mechanism of ecosystem service tradeoff/synergy, and function optimization. An optimization model of ecosystem function and an improvement path for eco-product supply are introduced. The role of functional traits in the maintenance of ecological function and services is also established, and social–ecological responses to afforestation in karst desertification control are discussed.
    Keywords: structural trait ; element trait ; physiological trait ; leaf ; root ; karst ; ecosystem service supply ; value accounting ; eco-industry ; karst desertification environment ; farmland hydrological cycle ; agroforestry ; agronomic measures to water saving ; planting combinations ; investment strategy ; plant adaptability ; soil ; response ; biodiversity ; ecosystem services ; forests ; karst desertification ; plant functional traits ; structure ; landscape security pattern ; sensitivity ; landscape connectivity ; Guanling County ; Guizhou ; ecological products ; value realization ; ecological industry ; resilient landscape ; rural planning ; resilience assessment ; karst rocky desertification control areas ; karst forest ; vegetation water use strategy ; hydrogen and oxygen stable isotopes ; hydrologic niche separation ; principal component analysis ; redundancy analysis ; karst rocky desertification area ; species diversity ; evaluation indicator systems ; fuzzy integrated evaluation ; karst spring ; dissolved organic carbon/nitrogen ; rocky desertification ; terrestrial ecosystem ; soil aggregate stability ; soil nutrients ; vegetation restoration ; karst rocky desertification ; forest ; karst desertification control ; loquat ; intercropping peanut ; N2O emission ; Abies fanjingshanensis ; microbial carbon use efficiency ; physicochemical indices ; bacteria ; fungus ; structural optimization ; water and fertilizer regulation ; functional improvement ; forests ecosystem ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: Processing and Conversion of Oil and Gas: Modeling, Control, Simulation, and Optimization describes the core of the activity of petrochemical engineers, process controller engineers, industrial engineers, energy engineers, and researchers in the oil and gas field. This reprint explores the modeling, control, simulation, and optimization of new and revamped petrochemical processes using proven software. Thus, it offers novel illustrative examples, prospective applications, and solutions to improve these processes. This reprint aims to combine theoretical principles with examples modeled by commonly used simulation software employing steady-state or dynamic process simulation. Furthermore, applying numerical methods and optimization at both the theoretical and practical levels is within the scope of this reprint.
    Keywords: jet stability ; swirl ; twist ; dominant mode ; Brassica Napus ; fatty acid methyl esters ; 2-Ethyl-2-hydroxymethyl-1,3-propanediol ; viscosity ; batch reactor ; kinetics ; self-excited oscillation pulse jet ; nozzle ; large eddy simulation ; peak velocity ; cavitation number ; coal tar ; wash oil ; nitrogen-containing compounds ; indole ; formamide equilibrium extraction ; price bubbles ; bubble length ; petroleum products ; GSADF ; Pakistan ; pipeline safety ; risk classification ; pipeline failure ; fuzzy analytic hierarchy process ; pipeline risk assessment ; shale gas pipelines ; pressure gradient ; gas–liquid two-phase flow ; flow patterns ; Generalized Additive Model ; dimensionless numbers ; discrete element method ; optimal design ; simulation analysis ; anti-corrosion pill particles ; butyl acetate ; acetic acid ; n-butanol ; esterification ; membrane reactor ; reactive distillation ; amberlyst-15 catalyst ; energy efficiency ; economic evaluation ; methyl isobutyl ketone (MIBK) ; acetone self-condensation ; selective hydrogenation ; process development ; heat integration ; economic analysis ; nano-Pd/nano-ZnCr2O4 catalyst ; dimethyl carbonate ; dimethyl oxalate ; oxidative carbonylation ; azeotropic distillation ; profitability analysis ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: It is currently apparent that extracellular ATP's physiological effect is mediated by its interaction with specific purinergic receptors. All purinergic receptors are divided into P1-purinoreceptors and P2-purinoreceptors. Each of the subtypes is divided into a number of families. For instance, P2 receptors are divided into P2X and P2Y receptors according to the mechanism by which their effect is realized: P2Y are G-protein-coupled receptors, while P2X receptors are ligand-operated ion channels. P2X receptors are important molecular therapeutic targets, the malfunctioning of which leads to severe complications in the physiology of humans and animals and causes dangerous diseases. The search for compounds that can modulate the function of purinergic receptors can lead to the creation of new drugs that are effective in central and peripheral nervous system and immune system disease treatment, including neuroinflammation, hypoxia/ischemia, epilepsy and neuropathic pain. In this Special Issue, we wish to offer a platform for high-quality publications on the latest advances in the identification of P2X/Y- and P1-receptor blockers, functions and regulation by them; the characterization of these receptor signaling networks and crosstalk; mechanisms underlying the role of purinoceptors in neurodegenerative illnesses as well as chronic neuronal changes following acute noxious damage and therapeutic opportunities associated with regulation of purinergic receptor activity.
    Keywords: adenosine receptors ; adipogenesis ; osteogenesis ; adipose tissue ; bone marrow ; obesity ; neonatal seizures ; development ; ATP ; purinergic signalling ; P2X7 receptor ; endometriosis ; adenosine ; P2Y ; P2X ; ectonucleotidases ; pain ; inflammation ; endometrium ; CD73 ; CD39 ; P2Y2 receptor ; P2X4 receptor ; canine ; dog ; DH82 ; macrophage ; neuroinflammation ; antinociception ; cerebral ischemia ; oxygen-glucose deprivation ; A2B receptors ; oligodendrocyte differentiation ; demyelination ; retina ; purinergic modulation ; glycinergic neurotransmission ; microglia ; neurodegeneration ; glycine transporters ; guanosine ; stroke ; neuroprotection ; purinergic signaling ; purinergic receptors ; autoimmune disease ; astroglia ; G protein-coupled receptor 17 (GPR17) ; neurite outgrowth ; montelukast ; NG2 ; ex vivo organotypic brain slice co-culture ; neurodegeneration and neuroregeneration ; n/a ; macrophages ; P2X7R ; pore formation ; inflammasome activation ; inflammatory diseases ; gallic acid ; visceral pain ; depression ; hippocampus ; spinal cord ; dorsal root ganglion ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: The reprint provides the most relevant and state-of-the-art in the field, including recent developments in the production of natural compounds from various bioresources, and their formulations as bioactives. This reprint also covered the engineered approaches for enhanced biological properties and their potential applications. Identification of novel compounds and bioprocess tools to improve the quantity and quality of bioactive compounds and their formulations are exclusively covered in this reprint.
    Keywords: anti-solvent ; enzymatic saccharification ; EMIM-Ac ; ethanol ; ionic liquid ; lignocellulosic biomass ; recycling ; agro-industry ; microencapsulation ; bioactive compounds ; in vitro digestion ; yogurt ; cannabis ; cannabinoids ; postharvest ; drying ; curing ; storage ; biosynthesis ; pre-treatments ; sorption isotherm ; Raphanus sativus L. ; recombinant IFN-α2a ; apoptosis ; antiviral and antitumor activity ; Japanese knotweed rhizome bark ; SARS-CoV-2 ; COVID-19 ; virus neutralization test ; nano-formulation ; nutraceuticals ; prebiotics ; nanofabricated delivery system ; liposomes ; nano-emulsions ; Abelmoschus manihot ; neurodegenerative disease ; oxidative stress ; proliferation ; inflammation ; nucleotide excision repair ; Actinosynnema pretiosum ; ansamitocin P-3 ; ssgA ; AdpA ; morphological differentiation ; pomegranate ; pomace ; extraction ; biological activity ; functional beverages ; sensory quality ; vitamins ; formulation ; homogeneous systems ; hydrophile–lipophile balance ; Emblica officinalis ; phytochemicals ; hyperlipidemia ; pharmacology ; nanoformulation ; Prunus mume ; vasorelaxant ; hypertension ; angiotensin receptor blockers ; agro-waste ; valorization ; value-added bioproducts ; micro/nano encapsulation ; agri-food-pharma applications ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: The papers published in this Special Issue report on recent studies investigating the exploitation of by-products produced by the food industry. The topics investigated include the extraction setups used for valuable food waste by-products and their applications as adjuncts to food preparation; the appropriate selection of solvents and extraction processes; and the interactions between extracted fractions and supplementary foods. The papers evaluate a wide variety of foodstuffs and provide results regarding the extension their shelf-lives and activities as functional foods.
    Keywords: by-product ; rheological properties ; optimization ; melting profile ; antioxidant activity ; mayonnaise ; olive mill wastewater ; oxidative stability ; phenolic extract ; pork ; fatty acid ; amino acid ; mineral ; meat ; sustainability ; spent biomass ; prebiotic potential ; enzymatic digestion ; biorefinery ; circular economy ; by-products ; ovine scotta ; bioactive peptides ; bromelain ; pancreatin ; dipeptidyl peptidase IV inhibition ; ovine second whey cheese ; enzymatic hydrolysis ; wasted bread ; bioprocessing ; lactic acid bacteria ; soil amendment ; byproducts ; vegetable oil industry ; phenolics ; flavonoids ; photochemiluminescence ; cold-pressed oil by-product ; gum ; thixotropic behavior ; low-fat vegan mayonnaise ; thickeners ; gelling agents ; tomato pomace ; lycopene ; β-carotene ; extraction ; food by-products ; deep eutectic solvents ; non-thermal drying ; stilbene ; vine shoots ; viticulture waste ; trans-resveratrol ; ε-viniferin ; Italian varieties ; no-waste ; omega-3 ; smart sensors ; reuse ; fish oil industry ; recovery ; chemometrics ; lipid profile ; aquafaba ; cold-pressed oils ; confocal laser scanning microscopy ; egg replacement ; physicochemical properties ; radical scavenging activity ; vegan mayonnaise ; Amberlite resin ; hazelnut skin ; polyphenols ; Pinot noir pomace ; solid–liquid extraction ; valorization ; fatty acids ; derivatization ; cranberry pomace ; dietary fiber ; technological properties ; kiwi byproducts ; probiotic ; prebiotic ; Lactobacillus casei ; ingredients ; functional foods ; microbial spoilage ; lipidic oxidation ; antioxidant ; predictive microbiology ; food preservation ; food safety ; sustainable strategy ; by-product reuse ; kinetic parameters ; Olea europaea ; waste reuse ; inulin ; high polymerization degree ; functional pasta ; glycemic index ; prebiotics growth ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint presents the published papers of a Special Issue titled Antioxidant Activity of Essential Oils, of the journal Antioxidants, MDPI. Obviously, essential oils are a point of huge interest, due to them being rich in bioactive substances (with their recognised antioxidant, immunomodulatory, antibacterial, antiviral, etc., effects) and are also used extensively in the beauty/cosmetic industry, food products, etc. Considering the global trend of "return to nature", both in eating habits/nutrition, and in the adjuvant therapies (implying essential oils) addressed in the case of numerous diseases, and taking into account the interest of the authors who submitted their papers, the current topic can be considered to be of great interest and with increased and promising potential for future research.
    Keywords: allyl compounds ; molecular dynamic ; antioxidant enzyme ; oxidative stress ; phytochemical study ; Artemisia judaica ; essential oil ; wound healing ; inflammatory markers ; antibiofilm activity ; antioxidant activity ; Ammi visnaga L. ; chemical composition ; gas chromatography-mass spectrometry ; circular economy ; volatile compounds ; antioxidants ; pro-oxidants ; enzymatic activity ; gas chromatography ; proanthocyanidins ; polyphenols ; Salvia officinalis ; chemical analysis ; aromatherapy ; inhalation ; TBARS ; FRAP ; colour parameter ; linseed and vitamin E ; oregano and rosemary ; microbiological profile ; beef meat ; phytochemicals ; medicinal plants ; plant-based nanostructures ; eco-friendly nanotherapeutics ; therapeutics ; phytobiotics ; apiaceae family ; Valeriana pilosa ; antioxidant activities ; molecular docking ; Embelia ribes Burm. ; Vidanga ; essential oils/extracts ; embelin ; vilangin ; pharmacology ; phytochemistry ; plant-based compounds ; natural products ; Amazon ; medicinal plant ; bioactive compounds ; S. edelbergii ; essential oils ; GC-MS analysis ; in vitro and in vivo biological activities ; antioxidant ; phytotoxic ; molecular modeling ; virtual ligand screening ; Amazonian natural products ; Artemia salina ; 1,8-cineole ; (Z)-α-trans-bergamotene ; citrus essential oils ; natural aromatic compounds ; therapeutic effects of citrus EOs ; characterization of citrus EOs ; new species ; Rosmarinus officinalis ; Salvia rosmarinus ; aromatic herbs ; wastes ; residues ; LC-HRMS/MS ; sweet orange ; cold pressing ; hydrodistillation ; scavenging activity ; reducing capacity ; virulence factors ; quorum sensing ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-07-14
    Description: The reprint focused on innovative developments in the fields of advanced propulsion system and thermal management technology. Propulsion systems develop along the direction of wide speed range and long endurance both for civil aircrafts and military applications. The research works of propulsion systems mainly include overall design, combustion, aerodynamic, internal flows and heat transfer etc. High efficiency is pursed not only by optimized designs but also from development of materials as well as application of new fuel. Along with development of high efficiency propulsion system, thermal management technology is also developed to meet the demand of external aerodynamic heating and internal combustion heat at a high flight speed. Common thermal management technology includes blade cooling in gas turbines and regenerative cooling in rocket engines. Thermal protection of engines achieves high efficiency by heat transfer enhancement, such as use of superficial fluid, nanofluids and new designed roughened surfaces. Also, some heat transfer enhancement methods in heat exchangers, battery and fuel cells are also introduced into propulsion systems.
    Keywords: auto-ignition ; supersonic flow ; initial flame kernel ; oblique shock ; recirculating region ; improved body force model ; off-design ; Reynolds-averaged Navier–Stokes equations ; meridional entropy gradient ; rotor 37 ; rolling motion ; subcooled flow boiling ; transverse flow ; subchannel ; VOF ; printed circuit heat exchanger ; NACA airfoil fins ; micro gas turbine recuperator ; thermo-hydraulic ; parametric study ; ventilation ; solar greenhouse ; numerical simulation ; system design ; n/a ; thrust vector control ; supersonic jet ; nozzle ; flow entrainment ; Coanda effect ; schlieren method ; scramjet ; regenerative cooling ; coupled heat transfer ; pyrolysis ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Afforestation/reforestation (or forestation) has been implemented worldwide as an effective measure towards sustainable ecosystem services and addresses global environmental problems such as climate change. The conversion of grasslands, croplands, shrublands, or bare lands to forests can dramatically alter forest water, energy, and carbon cycles and, thus, ecosystem services (e.g., carbon sequestration, soil erosion control, and water quality improvement). Large-scale afforestation/reforestation is typically driven by policies and, in turn, can also have substantial socioeconomic impacts. To enable success, forestation endeavors require novel approaches that involve a series of complex processes and interdisciplinary sciences. For example, exotic or fast-growing tree species are often used to improve soil conditions of degraded lands or maximize productivity, and it often takes a long time to understand and quantify the consequences of such practices at watershed or regional scales. Maintaining the sustainability of man-made forests is becoming increasingly challenging under a changing environment and disturbance regime changes such as wildland fires, urbanization, drought, air pollution, climate change, and socioeconomic change. Therefore, this Special Issue focuses on case studies of the drivers, dynamics, and impacts of afforestation/reforestation at regional, national, or global scales. These new studies provide an update on the scientific advances related to forestation. This information is urgently needed by land managers and policy makers to better manage forest resources in today’s rapidly changing environments.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; simulation modeling ; shear strength ; stand structure ; vegetation restoration ; surface runoff ; soil and water conservation function ; soil enzymes ; riverbank ; evapotranspiration ; human activity ; afforestation ; Artemisia ordosica ; forest cover ; precipitation variation ; soil bioengineering ; base flow ; Poyang Lake Basin ; in situ calibration ; quantification ; chlorophyll fluorescence ; photoprotection ; remote sensing ; root distribution ; ecosystem model ; CASA ; afforestation ecosystem ; phenophase ; vegetation cover change ; soil characteristics ; Robinia pseudoacacia L. and Pinus tabulaeformis Carr. mixed plantations ; composted pine bark ; water-energy balance ; sediment load ; soil respiration ; energy partitioning ; soil microbial biomass ; transpiration ; net primary productivity ; spatio-temporal scales ; seedling quality ; peat moss ; fresh pine sawdust ; understory plants ; ring-porous trees ; different climatic conditions ; dye tests ; structural equation model ; Loess Plateau ; evapotranspiration (ET) ; Pinus engelmannii Carr. ; empirical statistics ; heat dissipation probes ; MODIS ; slope change ratio of cumulative quantities (SCRCQ) ; soil water balance ; LAI ; climate fluctuation ; BTOPMC model ; living brush mattress ; vegetation greening ; streamflow ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-12-06
    Description: Pumped storage technology is a large-scale, efficient, flexible and clean energy storage technology. The core of it is the design of pumped storage units, which involves the operation and flow characteristics of vane hydraulic machinery under pump and turbine modes, as well as the complex flow conditions of the upstream and downstream flow channels of the units. With this as the background, this book expounds on the relevant problems and their solutions, providing a scientific basis for the development of pumped storage technology. I hope this book can provide as a useful reference for readers.
    Keywords: tip clearance ; vertical axial flow pump ; whole channel numerical simulation ; pressure pulsation ; leakage vortex ; bulb tubular pump ; numerical simulation ; adjusting speed ; transition process ; pressure fluctuation ; pump turbine ; flow energy loss ; flow–head stability ; guide vane opening ; V-inclined pipe ; sand transport ; critical velocity ; flow pattern ; orthogonal test method ; lateral intake ; CFD numerical simulation ; diversion pier ; prefabricated pumping station ; centrifugal pump ; energy characteristics ; internal flow field ; test ; integrated pump gate ; inlet channel ; outlet channel ; hydraulic performance ; “S” shaped airfoil ; bidirectional axial flow pump ; axial flow pumps ; energy ; cavitation ; numerical calculation ; Francis turbine ; sediment erosion ; clearance ; CFD ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: From a biological perspective, the subterranean realm is one of the less studied, but at the same time, one of the most promising, theatres for new findings and research. Compared to those on the surface, the ecological conditions occurring in subterranean habitats are relatively simple, and this may be an optimal scenario for understanding the mechanisms allowing the colonization, adaptation, and evolution of species, as well as their interactions within local communities. Diversity in subterranean habitats is often overlooked, and few studies embrace whole communities or try to assess functional relationships between species. This Special Issue reprint comprises papers covering a wide range of aspects related to the distribution, composition, and roles of subterranean communities occurring in different typologies of subterranean habitats.
    Keywords: cave biology ; subterranean habitats ; vertebrates ; invertebrates ; community dynamics ; biospeleology ; hypogean ; conservation ; biodiversity ; troglobite ; troglophile ; trogloxene ; extreme environment ; niche ; epikarst ; classification trees ; Copepoda ; random forests ; Diptera ; Limonia ; Limonia nubeculosa ; Neolimonia ; Trichoceridea ; cave community ; prey ; food resources ; occupancy ; abundance ; Astyanax ; Spelaeomysis ; Troglomexicanus ; Speocirolana ; Toro cave ; Sierra de El Abra ; troglomorphy ; stygobite ; fieldwork ; wild fish ; comparative biology ; behavior ; troglomorphism ; olfactory test ; infrared movies ; amino acids ; chondroitin ; plasticity ; cybernetics ; ecology ; cavefish ; dissolved oxygen ; cave evolution ; Astyanax mexicanus ; Ostracoda ; Yucatán Peninsula ; cenotes ; mitochondrial marker ; geometric morphometrics ; population ecology ; growth ; movements ; São Domingos karst area ; subterranean fishes ; evolution ; origin of troglobites ; Brazil ; subterranean biology ; environmental science ; biogeography ; distribution records ; groundwater ; underwater caves ; cenote ; mysid ; stygobiont ; bioindicator ; accidental cave visitors ; Arachnida ; Araneae ; arid ; levant ; Mediterranean ; species diversity ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSV Zoology & animal sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-11-17
    Description: Over the last few decades, the Mediterranean Diet (MD), characterized by a high intake of vegetables, legumes, fruits, nuts, dairy products and non-refined cereals, a moderate intake of fish and poultry, and a low intake of red meat and sweets, has been recognized as a model for healthy eating. Indeed, adhering to the MD reduces the risk of metabolic and non-communicable diseases, including type 2 diabetes, metabolic syndrome, obesity cardiovascular disease and cancer. As an integral part of the traditional Mediterranean lifestyle, regular physical activity (PA) is also associated with a reduced risk of chronic degenerative diseases, even if results often vary according to different types, duration and intensity or volume of PA. The World Health Organization recommends performing moderate-intensity PA for ≥150 min/week, and vigorous-intensity PA for ≥2 days/week to have these health benefits. It is viable to hypothesize that promoting adherence to the MD along with PA guidelines might provide a more comprehensive endorsement to obtain greater health benefits, over and above those acquired separately by the MD and PA. Thus, the ongoing promotion and monitoring of the MD pattern, including eating habits and PA, is crucially important at all life stages. Potential topics may include, but are not limited to, examining the impact of adherence to the MD and PA on health in different life stages as well as on metabolic risk factors and subsequent disease outcomes.
    Keywords: Mediterranean diet ; adherence ; Portuguese immigrants ; California ; Mediterranean Diet ; sustainable diet ; food frequency questionnaire ; diet self-perception ; socioeconomic profile ; health status ; adult population ; deprivation index ; lifestyle ; diet ; physical activity ; BMI ; socioeconomic status ; dietary supplements ; fitness ; MDSS ; IPAQ-SF ; cancer ; diet patterns ; cohort study ; epidemiology ; children ; youth ; kindergarten ; primary school ; secondary school ; faculty ; diabetes ; pediatrics ; food ; nutrition ; glucose ; weight ; blood pressure ; adolescence ; metabolic profile ; awareness ; health ; geographical location ; ethnic ; nutrition guidelines ; chronic disease ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Greenhouse cultivation provides an artificially controlled environment for the year-round production of vegetables, and has played an increasingly important role in agriculture production systems in recent decades. Recent works have shown that improving greenhouse conditions can promote the growth of vegetables and enhance the uptake of nutrients, leading to better vegetable quality. Meanwhile, greenhouse conditions not only directly influence soil nutrient cycling processes and properties, but also indirectly affect them by regulating vegetable root growth and plant–soil interactions. This Special Issue features twelve original research articles that deal with the effects of novel greenhouse practices and strategies on the yield and quality of horticulture crops, as well as greenhouse soil properties. Among these publications, three studied the effects of fertilizers, including organic and macro- and micro-nutrient fertilizers, on the growth and nutrient uptake of vegetables. Two articles described the effects of water and nutrient supply using irrigation or hydroponic supplying systems on the yield and quality of vegetables. Four articles investigated the effects of environmental conditions (mainly light and temperature) on the growth and quality of vegetables. In terms of degenerated greenhouse soil, three articles showed how reductive soil disinfestation decreased soil salinity, improved soil quality, and inactivated soil-borne pathogens.
    Keywords: daily light integral ; cucumber seedling ; seedling quality ; flower development ; boron ; application methods ; growth ; fruit quality ; tomato ; protected greenhouse ; soilless culture ; poultry manure ; yield enhancement ; cucumber ; univariate analysis ; multivariate analysis ; nutrient uptake ; sweet onion ; nerokremmydo ; aeroponic ; floating ; nutrient film technique ; bulb ; application rate ; nitrate ; organic acid ; soil-borne pathogens ; soil pH ; sulfate ; growth rate ; root morphology ; ammonium to nitrate ratio ; nutrient solution composition ; nitrogen efficiency ; net assimilation rate (NAR) ; leaf nitrogen ; fruit temperature ; dry matter ; chlorophyll ; microbial activity ; organic fertilizer ; plastic shed cultivation system ; reductive soil disinfestation ; soil quality ; aromatic substances ; carbon exportation ; flavor quality ; nutrient and function indicator ; overall appearance ; microbial community ; microbial function ; co-occurrence network ; soil ecosystem ; alternate drip irrigation under mulch ; water ; zeolite amount ; tomato growth ; water use efficiency ; principal component ; solar radiation ; humidity ; temperature ; irrigation water use efficiency ; yield ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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