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  • Books  (359)
  • Biology Research.  (198)
  • Human geography.  (161)
  • Cham :Springer International Publishing :  (359)
  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biology Technique. ; Medicine Research. ; Biology Research. ; Surgery. ; Experimental Organisms. ; Biomedical Research. ; Biological Techniques. ; Surgery.
    Description / Table of Contents: Chapter 1 -- The Basics -- Chapter 2. Collecting Specimen and Harvesting Tissues -- Chapter 3. Drugs Administration -- Chapter 4. Surgical Principles -- Chapter 5. Vascular Surgery. .
    Abstract: This book fills the current void of academic writings on laboratory mouse operation, giving research scientists, graduate students, and laboratory technicians an authoritative textbook and definitive laboratory companion. It covers mouse anatomy, the handling of the mouse, anesthesia, drug administration, specimen collection, organ harvesting and daily laboratory skills as well as advanced micro-surgery techniques. Its detailed description of mouse anatomy corrects many inaccuracies and misconceptions in the literature. It provides a wealth of basic laboratory skills and numerous advanced surgical techniques. The step-by-step explanations, with extensive photographic images and videos, improve the current understanding and practice of laboratory mouse operations. This book lays the foundation of laboratory mouse operations by offering a clear understanding of the basic principles, updated anatomic studies, and providing invaluable practical tools. It serves a wide audience, including laboratory animal scientists, pharmaceutical science researchers, graduate students in these fields, micro surgeons, veterinarians, and laboratory technicians. .
    Type of Medium: Online Resource
    Pages: XVII, 1070 p. 3067 illus., 3039 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783030745011
    DDC: 570.28
    Language: English
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  • 2
    Keywords: Geography. ; Ethnology. ; Culture. ; Human geography. ; Cultural geography. ; Geography. ; Regional Geography. ; Regional Cultural Studies. ; Social and Cultural Geography.
    Description / Table of Contents: Introduction -- The Physical Environment -- Biological Environment -- The First People -- People on the Landscape -- Making a Living -- Life at Home -- Conclusions.
    Abstract: For the past 9,000 years, people lived and flourished along the 1,000-mile Aleutian archipelago reaching from the American continent nearly to Asia. The Aleutian chain and surrounding waters supported 40,000 or more people before the Russians arrived. Despite the antiquity of continuous human occupation, the size of the area, and the fascinating and complex social organization, the region has received scant notice from the public. This volume provides a thorough review describing the varied cultures of the ancestral Unangax̂, using archaeological reports, articles, and unpublished data; documented Unangax̂ oral histories, and ethnohistories from early European and American visitors, assessed through the authors’ multi-decade experience working in the Aleutian Archipelago. Unangam Tanangin ilan Unangax̂/Aliguutax̂ Maqax̂singin ama Kadaangim Tanangin Anaĝix̂taqangis (Culture and Archaeology of the Ancestral Unangax̂/Aleut of the Aleutian Islands, Alaska) begins with a description of the physical and biological world (The Physical Environment and The Living Environment) of which the Unangax̂ are part, followed by a description of the archaeological research in the region (The People). The rest of the book addresses ancestral Unangax̂ life including settlement on the land, and the characteristics of sites based on the activities that took place there (People on the Landscape). From this broad perspective, the view narrows to the people making a living through hunting, fishing, and collecting food along the shore-line, making their intricate tools, storing and cooking food, and sewing and weaving (Making a Living); household life including house construction, households, and the work done within the home (Life at Home); and the personal changes an individual goes through from the time they are born through death, including spiritual transitions and ceremonies (Transitions), and the evidence for these events in the material record. This book is written in gratitude to the Unangax̂ and Aleut people for the opportunity to work in Unangam Tanangin or the Aleutian Islands, and to learn about your culture. We hope you find this book useful. The purpose of this book is to introduce the broader public to the cultures of this North Pacific archipelago in a single source, while simultaneously providing researchers a comprehensive synthesis of archaeology in the region.
    Type of Medium: Online Resource
    Pages: XXI, 419 p. 64 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031442940
    DDC: 910
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Environment. ; Climatology. ; Sustainability. ; Human geography. ; Urban ecology (Biology). ; Agriculture. ; Environmental Sciences. ; Climate Sciences. ; Sustainability. ; Human Geography. ; Urban Ecology. ; Agriculture.
    Description / Table of Contents: Chapter 1-Introduction -- Chapter 2-Evidences from climate change dynamics -- Chapter 3-Sustaining livelihoods for survival -- Chapter 4-Cultural influence for revitalizing health traditions and vulnerable environments -- Chapter 5-Holistic health for well-being -- Chapter 6-Summary and policy options. .
    Abstract: This book discusses the dynamics and resource management qualities of the peri-urban interface to address climate change consequences, focusing on the peri-urban region of the global city of Bengalaru. In 5 chapters, the authors document the unique challenges experienced in peri-urban areas, including soil-water vegetation dynamics, local and regional impacts on water bodies (surface and groundwater), food production issues, and the inhibited adaptive capacity of local communities. The book also provides knowledge on implementations of environmental management by local institutions, government interventions that have acted as catalysts in promoting community based adaptation strategies, and the physical, social and economic aspects of rural-urban dynamics. The book not only adds to the scarce existing literature on peri-urban contexts, but also addresses the role of culture in protecting ecological landscapes and how traditions play an important role in coping with climate change. Furthermore, the authors expand on these climate change coping mechanisms in peri-urban areas, taking into account local cultural factors and interesting governance interventions in the context of health. The book will be of interest to planners, policy makers, and students and researchers engaged in rural-urban dynamics and climate change adaptation. .
    Type of Medium: Online Resource
    Pages: XX, 164 p. 116 illus., 109 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030185176
    DDC: 333.7
    Language: English
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  • 4
    Keywords: Biotechnology. ; Medicine Research. ; Biology Research. ; Biomedical engineering. ; Biotechnology. ; Biomedical Research. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Introduction -- Part 1. History of UPE research -- Mitogenetic rays -- Oxidation, free-radicals and ultraweak luminescence -- Biophotons and the International Institute of Biophysics (IIB) -- Part 2. Physics of light and light research -- Physics of photon emission -- Chemiluminescence as a tool for free radical research -- Highly sensitive imaging and spectral analysis of UPE from biological systems and their application -- Part 3. Molecular mechnisms of UPE -- Free radicals in biology -- Ultraweak luminescence from aqueous systems -- Chemiluminescence in oxidation of hydrocarbons: mechanistic fundamentals -- Chemiluminescence in oxidation of fatty acids and lipids -- Chemiluminescence in protein oxidation -- Emitters of endogenous biological chemiluminescence: quantum chemical modeling insights -- Enzymatic sources of free radicals -- Part 4. UPE research in life science -- Luminescence of animal tissues and vegetable oils -- Ultraweak photon emission from human body in relation to anatomy and histology -- Chronobiological aspects of spontaneous ultra-weak photon emission in humans: Ultradian, circadian and infradian rhythms -- Autoluminescence in seedlings: applications -- Application potentiality of Delayed Luminescence in Medicine, Biology and Food Quality researches -- Part 5. Mitogenetic effect and related phenomena: unresolved problems of UPE -- Mitogenetic effect: preface -- Mitogenetic effect in biological systems -- Physical properties of mitogenetic radiation -- Secondary, degradation and necrobiotic radiation -- Mitogenetic research in medicine: radiation of blood and cancer diagnostics -- Part 6. Non-chemical distant interaction hypothesis - pro et contra -- Non-chemical distant interaction: preface -- The possible functions of electromagnetic cell communication -- Understanding of Fritz-Albert Popp’s biophoton theory from the viewpoint of a biologist -- Limits to the information transfer through UPE -- Quantum nonlocality and biological coherence -- Part 7. Perspectives -- Integrating ultraweak photon emission in mitochondrial research -- Selected biophysical methods for enhancing biological autoluminescence -- Upconverting nanoparticles as sources of singlet oxygen -- Upconverting nanoparticles as sources of singlet oxygen -- Delayed Luminescence as a tool to study the structures of systems of biological interest and their collective long-living excited states -- Index.
    Abstract: This book addresses the phenomenon of biological autoluminescence (also known as ultraweak photon emission, UPE, biochemiluminescence, or biophotons) and deals with a very broad spectrum of subjects, ranging from basic observational studies to molecular mechanisms, free-radical processes, physics of electron excitation and photon emission, as well as detection techniques. The chapter topics include UPE in plants, animals, and the human body; microorganisms and subcellular structures; and model systems, illustrating its high prevalence. Several sections of the book provide some backstory, with emphasis on methodology, unresolved questions, and existing controversies. The authors raise and discuss complex, potentially divisive aspects: Are there any reasons to assume the existence of non-chemical interaction in biological systems? Can research results in the field of mitogenetic radiation, delayed luminescence, and oxychemiluminescence of model systems, be correctly interpreted? What does the future hold for this area of research? Altogether, this publication gives the reader a thorough overview of biological autoluminescence (UPE, biophotonics) research, making it ideal for students and researchers who are new to the area as well as those who are specializing in it.
    Type of Medium: Online Resource
    Pages: XII, 521 p. 345 illus., 198 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031390784
    DDC: 660.6
    Language: English
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  • 5
    Keywords: Biogeography. ; Physical geography. ; Materials science. ; Medicine Research. ; Biology Research. ; Ecology . ; Biogeosciences. ; Earth System Sciences. ; Materials Science. ; Biomedical Research. ; Terrestial Ecology.
    Description / Table of Contents: Methods for studying the interactions in biogenic–abiogenic systems -- Geochemistry of biogenic-abiogenic systems -- Biomineralization and nature-like materials and technologies-Medical geology -- Organic mineralogy-Biomineral interactions in soil-Effect of microorganisms on natural and artificial materials -- Philosophical and historical aspects of interdisciplinary research.
    Abstract: The book represents a collection of papers presented at VII International Symposium "Biogenic - abiogenic interactions in natural and anthropogenic systems" that was held on 26-29 September 2022 in Saint Petersburg (Russia). Papers in this book cover a wide range of topics connecting with interactions between biogenic and abiogenic components in lithosphere, biosphere and technosphere. The main regarding topics are following: biomineralization in living organisms and nature-like materials; biomineralization in geosystems; geochemistry of biogenic-abiogenic systems; biomineral interactions in soil; interaction of microorganisms with natural and artificial materials; medical geology; philosophical aspects of interdisciplinary researchs.
    Type of Medium: Online Resource
    Pages: XIII, 675 p. 216 illus., 141 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031404702
    Series Statement: Springer Proceedings in Earth and Environmental Sciences,
    DDC: 578.09
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cardiovascular system. ; Physiology. ; Cardiology. ; Medicine Research. ; Biology Research. ; Medical sciences. ; Health. ; Sex. ; Cardiovascular Physiology. ; Cardiology. ; Biomedical Research. ; Health Sciences. ; Gender and Health.
    Description / Table of Contents: Attenuation of Bnip3 Mediated Doxorubicin-Induced Cell Death in Cardiac Myocytes -- Sex Dependent Regulation of Circadian Rhythms in Health and Disease -- Circadian Pharmacological Approach to Treat Myocardial Infarct -- GPER Function as a Determinant of the Progression of Atherosclerotic Disease in Women -- Novel Therapeutic Approach to Treat Cardiac-Rheumatology in Females -- Correlation between Sex, Immigration Status, Ethnicity, and Long-term Outcomes of Ischemic Stroke -- Risk Assessment and Predictive Modelling for The Heart-Brain Interface in Women -- Insomnia Interventions for Female Cardiac Patients -- Aortic Stenosis Progression, Cardiac Damage, and Survival: Comparison Between Men and Women -- Treatment and Management of Valvular Heart Disease and Cost-Effectiveness Analysis -- Association of Mortality and Acute Aortic Events with Ascending Aortic Aneurysm -- Improving Diagnosis and Treatment for Patients Who Suffer Spontaneous Coronary Artery Dissection (SCAD) -- Preeclampsia and Future Cardiovascular Health -- Cardiovascular Disease in Women with a History of Pregnancy Complications -- Hormone Replacement Treatment for Cardiovascular Disease -- Cardiovascular Mortality Following Early-Stage Breast Cancer -- Lipid Management for the Prevention of Atherosclerotic Cardiovascular Disease in Women -- Sex Differences in Cardiac Rehabilitation Enrollment -- Promoting Exercise and Physical Activity in Female Patients with Heart Disease -- Sex and Gender Differences in the Diagnosis, Treatment, and Outcomes of Coronary Artery Disease -- Sex Differences in Arterial Aging and its Implications on Cardiovascular Diseases -- Impact of a Novel Community-Based Lifestyle Intervention Program on Type 2 Diabetes and Cardiovascular Risk -- Clinical Outcomes Related to Heart Failure and Pulmonary Hypertension -- Examination of Health-Related Quality of Life in Women with Coronary Artery Disease -- The Risks and Benefits of Implantable Cardioverter-Defibrillator Generator Replacement -- The Effects and Roles of Estrogen in Managing Hypertension in Menopausal Women -- The Effects of Menopausal Hormone Therapy on the Vascular System -- Influence of Sex Differences in Non-Obstructive Coronary Artery Disease -- Diet1 and Resistance to High Cholesterol Levels and Cardiovascular Disease -- Interventions to Improve Clinical Outcomes Following Hospitalization for Heart Failure -- Sex-Dependent Cardioprotective Effects of the Phytoestrogen Resveratrol -- Blood Pressure Across a Woman's Life Cycle -- Women’s Fitness Levels and Heart Rate Response to Exercise -- Supervised Exercise Therapy Through Cardiac Rehabilitation following Peripheral Arterial Disease -- Sex Differences in ANT2-Mediated ATP Import into Mitochondria for Protection Against Hypoxia Lethal Injury.
    Abstract: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in women and men worldwide and represents a major financial burden to world health care systems. Importantly, CVD has eclipsed cancer as the leading cause of death for women globally. Through advancements in research and clinical testing, the symptoms and risk factors for CVD have been well established for men, but not for women. Consequently, there is an immediate need for new innovative research that will bridge this gap and allow for improved early diagnosis and treatment of CVD in women. This book will serve as a guide for health care providers to better understand the physiological, biochemical, and genetic differences in heart disease in women with the goal of providing improved education, awareness and treatment of cardiovascular disease in women. The book will cover topics such as: sex dependent clinical outcomes of cardiovascular disease, cardiac protection by estrogen, cardiac health during menopause, cardiac rehabilitation programs, fitness and exercise, cardio-oncology, shift work and the CVD risk, and pregnancy related CVD.
    Type of Medium: Online Resource
    Pages: VII, 446 p. 56 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031399282
    Series Statement: Advances in Biochemistry in Health and Disease, 26
    DDC: 573.1
    Language: English
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  • 7
    Keywords: Environmental sciences Social aspects. ; Sustainability. ; Human geography. ; Environmental geography. ; Environmental Social Sciences. ; Sustainability. ; Human Geography. ; Integrated Geography.
    Description / Table of Contents: 1-Environment, Society and Sustainability: A Human-Nature Interface -- 2-Social Welfare and Sustainable Development: Paradigm Shift -- 2-Ensuring Social Security for Child and the Elderly People -- 3-Geo-heritage and Geo-Ecotourism Conservation- Case Study -- 4-Resource Allocation and Sustainable Development -- 5-Welfare Schemes for Socially Vulnerable Segments -- 6-Population Growth, Poverty and Inequality -- 7-Illiteracy, Unemployment, Underemployment and Migration -- 8-Slums and Issues of Educational Sub-normality of Social Poor -- 9-Urbanization & Housing Affordability, Requirements of the Marginalized People -- 10-Gender Inequality, Women Health Issues and Women Empowerment -- 11-Climate Change and its Social Consequences and adaptation -- 12-Flood and its Impact on Human Livelihoods on Global South- Case study -- 13-Drought and its Associated Social Responses- Case study -- 14-Access to Basic Amenities, Healthcare Services and Mass Education -- 15-Sustainable Agriculture & Rural Development, Industrialization as a Source of Employment -- 16-Protection of Civil Rights, Transgender Equality, Vocal for Local and Ecofeminism -- 17-Conclusion.
    Abstract: This volume discusses a broad range of human welfare problems associated with and stemming from social issues, natural resource deficiencies, environmental hazards, vulnerability to climate change, and sustainability challenges. The chapters form a framework centered around the concept of social morphology, i.e. the role of humans in shaping society, and associated human-nature interactions which inform the ability to achieve sustainable welfare and well-being. The book is divided in six sections. Section I contains the introductory chapters where the book explores shifting interfaces between environment, society, and sustainability outcomes. Section II discusses contemporary issues of social welfare, and covers sustainable in geo-heritage and ecotourism. Section III addresses the roots of various social conflicts and inequalities in relation to overpopulation, poverty, illiteracy, employment concerns, and human migration. Section IV highlights social security and areas of social deprivation, including urban affordability, gender equality, and women’s health. Section V covers social issues resulting from natural hazards and disasters. Section VI concludes the book with a discussion of the way forward for social sustainability. The book will be of interest to students, researchers, policy makers, environmentalists, NGOs, and social scientists.
    Type of Medium: Online Resource
    Pages: XXIX, 739 p. 224 illus., 196 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030967604
    DDC: 304.2
    Language: English
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  • 8
    Keywords: Natural disasters. ; Social sciences. ; Human geography. ; Sustainability. ; Earth sciences. ; Natural Hazards. ; Society. ; Human Geography. ; Sustainability. ; Earth Sciences.
    Description / Table of Contents: Part I: Conceptualising Disaster and Risk -- Chapter 1. Hazard and Disaster Perception: Cognition, Response and Adaptation -- Chapter 2. Characterising Hazard and Disaster and Sustainable Development -- Chapter 3. Understanding Disaster Risk Reduction and Resilience -- Chapter 4. Traditional management of Disaster: Indigenous Knowledge, Insights and Strategies -- Part II: Approaches to Disaster Management -- Chapter 5. Different types of Risks and Vulnerability -- Chapter 6. Fields of Response to Disaster: Positive Response and Negative Response -- Chapter 7. Disaster Resilience by Indigenous Communities -- Chapter 8. Capacity Building and Community Based Disaster Preparedness -- Part III: Sustainability Through Indigenous Knowledge and Practice -- Chapter 9. Disaster Risk Identification and Mitigation with the help of Traditional Knowledge -- Chapter 10. Disaster Risk Reduction through local Knowledge and practice-case studies -- Chapter 11. Adaptation to different types of Disaster with Integration of local Knowledge-case studies -- Chapter 12. Climate Risk Management with Indigenous Perception and Strategies- case studies -- Part IV: Science-Policy Interface Through Indigenous Knowledge -- Chapter 13. Integration of Indigenous Knowledge in Policy Formulation -- Chapter 14. Insights from Regional and Field Studies on Micro Policies -- Chapter 15. Perspectives from Indigenous Knowledge in Sustainable Development -- Chapter 16. Integration of Perception Studies and Disaster Risks -- Chapter 17. Development of a holistic Regional Disaster Policy Framework based on Indigenous Knowledge -- Chapter 18. Identifying the gaps and Future Scopes in Disaster Risk Reduction and Resilience -- Chapter 19. Conclusion.
    Abstract: The book seeks to comprehend how indigenous knowledge systems of local communities can be effectively used in disaster management of various types. A prime example is the 2015 Sendai Framework for Disaster Risk Reduction, promoting indigenous environmental management knowledge and practices. Traditional knowledge of indigenous peoples includes information and insight that supplement conventional science and environmental observations, a comprehensive understanding of the environment, natural resources, culture, and human interactions with them which is not documented before. A great deal of this knowledge have been lost in translation. In this book, the authors attempt to keep a record of each and every traditional knowledge study of the indigenous communities in managing the disasters. The use of indigenous knowledge systems in disaster understanding and management is the primary focus of the chapters. This book is organized into four major sections. The first part gives an overview and help in conceptualizing the different concepts of hazard and disaster perception and how response and adaptation are connected with it. This part also discusses the concept of the connection between hazard and sustainable development and how the understanding of risk reduction and resilience can happen with the help of indigenous knowledge, insights, and strategies. The second part of the book introduces the different approaches to disaster and risk management. It establishes how vulnerability influences the risk associated with a hazard and the responses can be both positive and negative in disaster management. The approaches of the indigenous communities in managing a disaster, their resilience, capacity building, and community-based preparedness will be the area of prime focus in this chapter. Part 3 of this book describes the concept of sustainability through indigenous knowledge and practice. The sole highlight of this chapter is the indigenous knowledge efficacies in disaster identification, risk reduction, climate risk management, and climate action. The last section of the book explores how to meet the gaps between local knowledge and policy formulation. It highlights how traditional knowledge of the indigenous communities can prove to be beneficial in developing a holistic regional-based policy framework which will be easily accepted by the target stakeholders since they will be more acquainted with the local strategies and methods. This section ends with an assessment and discussion of the gaps and future scopes in disaster risk reduction through integrating local knowledge and modern technologies.
    Type of Medium: Online Resource
    Pages: XXIX, 604 p. 200 illus., 187 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031261435
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    DDC: 551
    Language: English
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  • 9
    Keywords: Geography. ; Environmental sciences Social aspects. ; Human geography. ; Economic history. ; Economic geography. ; Asia History. ; Regional Geography. ; Environmental Social Sciences. ; Human Geography. ; Economy-wide Country Studies. ; Economic Geography. ; History of South Asia.
    Description / Table of Contents: Preface -- Introduction -- Index -- Glossary -- Part 1 Geo-Physical Dynamics -- Part 2 Bio-Physical Aspects -- Part 3 Changes in Society -- Part 4 Land Resource and Land Use Patterns -- Part 5 Towards Food Security and Food Self-sufficiency -- Part 6 Changing Popular Dynamics -- Part 7 Rural Settlement Pattern -- Part 8 Urbanization: A Future Challenge -- Part 9 Trade, Communication and Industries for Economic Growth -- Part 10 Bangladesh in Growing International Sharing -- Part 11 Natural Hazards and Changes in Livelihood Pattern -- Part 12 Environmental Problems and Policies for Sustainable Living -- Part 13 Bangladesh Under Climate Change Threat -- Part 14 Development Policies and Future of Bangladesh.
    Abstract: This book focuses on the transformation of Bangladesh in respect to its people, geography, economy and environment. The authors discuss current problems such as vulnerability caused by environmental degradation in Bangladesh but also opportunities of this rapidly changing country. The book explains how the country is rapidly transforming from a rural subsistence agrarian based economic system to a new economic partner contributing to global processes. Bangladesh is presented as an example for the changes in the Global South, where a mismatch is often observed in linking resources and activities with environmental sustainability, possibly due to insufficient base-line knowledge. As faster growth is marginalizing resources to increase the GDP, the sustainability of resource exploitation is being questioned. The authors describe the vulnerable situation caused by possible sea-level rise, soil degradation, biodiversity loss, climate extremities, urbanization, and population displacement. This volume offers comprehensive knowledge about the geography and environment of Bangladesh and aims to help readers further investigate the issues and work on solutions. The book appeals to academics, professionals and students at all levels interested in Bangladesh as well as environmental problems and geographical issues in a rapidly transforming country. .
    Type of Medium: Online Resource
    Pages: X, 176 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031450938
    Series Statement: World Regional Geography Book Series,
    DDC: 910.021
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Medicine Research. ; Biology Research. ; Drug Delivery. ; Pharmaceutics. ; Pharmacology. ; Biomedical Research.
    Description / Table of Contents: Part 1: Patient-Centric Considerations.-Medicine Optimisation in Older -- Acceptability of drug formulations in older patients and effect on patient adherence -- Geriatric biopharmaceutics -- Excipient safety in older adults -- Part 2: Pharmaceutical Formulations Development for older Patients -- Oral and oromucosal formulation development and in vitro characterisation – patient-centric approaches for older adults -- Pulmonary drug delivery systems for older people -- Transdermal drug delivery systems for older patients -- Part 3 :Advanced Drug Delivery Systems for Older Patients -- Advanced oral drug delivery systems for older patients -- The ageing microbiome, pharmaceutical considerations and therapeutic opportunities -- Application of 3D printing in geriatric medicines, -- Application of electrospraying and advanced fabrication methods in geriatric medicines -- Vaccine development for older patients.
    Abstract: Pharmaceutical formulation design affects patient acceptability/adherence and pharmacokinetics of the drug. This is particularly important for older patients because of the physiological changes due to ageing and clinical/social circumstances related to medicine taking. This book provides a comprehensive review in the design of formulations to meet the needs of older patients. An overview of the key clinical, social and pharmaceutical factors affecting medication optimization, safety and acceptability in older adults is included, followed by patient-centric considerations including regulatory requirements, dosage form design and human factor studies. Advanced pharmaceutical technologies are discussed for their potential use in older adults such as 3D printing, long-acting oral formulations and novel vaccine technologies. The unique focus of the book will be of interest to pharmaceutical scientists in both industry and academia in searching for better formulations for older patients.
    Type of Medium: Online Resource
    Pages: XIII, 288 p. 63 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031358111
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 51
    DDC: 615.6
    Language: English
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