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  • Articles  (2)
  • Biochemistry and Biotechnology
  • Mice
  • 1970-1974  (2)
  • Medicine  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Post-capillary venules as the pathway for migrating B lymphocytes (1974)
    Springer
    Cell & tissue research 152 (1974), S. 299-303 
    Details
    ISSN: 1432-0878
    Keywords: Post-capillary venules ; Mice ; Pathway of B lymphocytes ; Autoradiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Histological observation on the mesenteric lymph node and Peyer's patches of C3H B mice, neonatally thymectomized, lethally irradiated and reconstituted with syngeneic bone marrow cells, showed that a large number of lymphocytes appeared selectively in the restricted territory surrounding the post-capillary venules. Severe depletion of lymphocytes persisted in most of the thymus-dependent areas. Lymphocytes were also observed passing through the walls of the post-capillary venules. Autoradiographic studies on the mesenteric lymph node of recipient B mice 30 minutes after intravenous injection of cells labelled with 3H-uridine and taken from lymph nodes of donor B mice showed that B lymphocytes could penetrate the walls of the post-capillary venules from the blood into the peripheral lymphoid tissues. The post-capillary venules, which are known as the recirculating route of T lymphocytes in normal animals, are thought to be the pathway of migrating B lymphocytes in B mice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00223952
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cell interaction at the maternal-embryonic interface during implantation in the mouse (1974)
    Springer
    Cell & tissue research 152 (1974), S. 525-542 
    Details
    ISSN: 1432-0878
    Keywords: Nidation ; Mice ; Cell interaction ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The interaction between the trophoblast and the maternal epithelium at early implantation was studied by means of light and electron microscopy. The uterine horns were fixed in situ and a double-embedding method was used to locate implantation sites. Observations were made on mice killed at 2 hour intervals 90–116 h. post coitum which covered the following stages: pre-attachment (i) with zona pellucida intact (ii) with zona pellucida in dissolution (iii) after loss of the zona; attachment; adherence; and invasion. The intact zona pellucida was electron opaque and of uniform density. In the stage of apparent dissolution it became electron dense and was trapped between trophoblast and epithelium. At preattachment the trophoblast cells were round. Subsequently they became long and attenuated, often with lysosomes in the cytoplasm proximal to the epithelial layer. Epithelial cells, which could be seen in various stages of degeneration were apparently phagocytosed by the trophoblast. Occasional pyknotic epithelial cells were seen, as well as some apparently normal ones which contained cytosegresomes. The possible reasons for their presence are discussed. The microvilli of the epithelial cells changed from regular and pointed at preattachment to short and irregular at adherence and invasion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00218936
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    Paper (German National Licenses)
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