ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Technical Procedures for the Synthesis of Carotenoids and Related Compounds from 6-Oxo-isophorone. IV. A Novel Concept for the Synthesis of (3RS, 3′RS)-, (3S, 3′S)- and (3R, 3′R)-9,9′-dicis-7,8,7′,8′-TetradehydroastaxanthinStarting from readily available intermediates of the synthesis of astaxanthin, (3RS, 3′RS)-, (3R, 3′R)- and (3S, 3′S)-9,9′-di-cis-tetradehydroastaxanthin (1, 1a and 1b, resp.) were synthesized, 1 and 1b for the first time. Key features of this concept are: a) use of the unprotected, acetylenic phosphonium salts 8-12, b) a two-step synthesis with 47% overall yield, and c) good chemical and optical purity of the end products.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19810640753
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