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  • Articles  (248,077)
  • Springer  (224,235)
  • American Association for the Advancement of Science  (14,831)
  • National Academy of Sciences  (8,449)
  • Nature Publishing Company
  • 1980-1984  (248,077)
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  • 1
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    Die Geschichte der Antarktisforschung (1984)
    Springer
    In:  EPIC3Naturwissenschaften, Springer, 71(12), pp. 599-608, ISSN: 0028-1042
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    Publication Date: 2014-06-04
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , notRev
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  • 2
    Electronic Resource
    Electronic Resource
    Creating New Enzymes With Chemistry (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 549-551 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] With a global market of $600 million predicted for mid-decade, industrial enzymes are an obvious target for biotechnology R&D. Exploiting recombinant DNA techniques and computer-aided molecular design systems, scientists hope to improve existing—indeed create new “custom ...
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    URL: http://dx.doi.org/10.1038/nbt0684-549
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  • 3
    Electronic Resource
    Electronic Resource
    New Technologies for Fermentation, Biological Conversion (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 555-555 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Although biotechnology is generally not a theoretical discipline, several researchers discussed important kinetic models. R. D. Tanner (Vanderbilt University, Tennessee) described use of non-constant parameters in the Monod model for growth kinetics. Dynamic phenomena such as hysteresis and ...
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    URL: http://dx.doi.org/10.1038/nbt0684-555a
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  • 4
    Electronic Resource
    Electronic Resource
    New Products (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 561-565 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Beckman Instruments, Inc. offers the model 164 UV-VIS variable wavelength absorbance detector for high pressure liquid chromatography. The detector features wavelength monitoring between 190–700 nm, a user-selectable time constant, a variety of flow cells, and wavelength programming. Write ...
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    URL: http://dx.doi.org/10.1038/nbt0684-561
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  • 5
    Electronic Resource
    Electronic Resource
    Citrobacter for Control of Cadmium (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 382-382 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] It's quite an achievement to evolve a scientific theory that is both erroneous and highly influential. Within modern microbiology, one outstanding example comes to mind. It is immortalized in two books: C. N. Hinshelwood's The Chemical Kinetics of the Bacterial Cell, published in 1946, and A. R. C. ...
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    URL: http://dx.doi.org/10.1038/nbt0584-382
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  • 6
    Electronic Resource
    Electronic Resource
    British Drug Giants Move into Biotech (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 388-395 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON, England—The giant British pharmaceutical houses are finally beginning to commit themselves to the new techniques of biotechnology. They are being led by the Boots Company, better known in Britain for its drug stores and its cough and cold remedies than for a massive research and ...
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    URL: http://dx.doi.org/10.1038/nbt0584-388
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  • 7
    Electronic Resource
    Electronic Resource
    NSF Evaluating Biotech Funding (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 396-398 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—The National Science Foundation, the basic science and engineering research grants agency in the U.S., is taking an agency-wide look at the biotechnology projects it is funding. The purpose is to decide how much more to spend and into what disciplines NSF should funnel ...
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    URL: http://dx.doi.org/10.1038/nbt0584-396
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  • 8
    Electronic Resource
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    Hybrid Analytical Techniques Hold Promise (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 432-434 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Instrumentation will be the key to good scientific investigation, according to G. Pimentel (Univ. of California, Berkeley), who provided the keynote address for the New Frontiers in Chemistry symposium at the 35th Pittsburgh Conference on Analytical Chemistry held in Atlantic City, NJ in March. ...
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    URL: http://dx.doi.org/10.1038/nbt0584-432
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  • 9
    Electronic Resource
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    Automated Chemical Synthesis of Peptides and DNA Fragments (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 445-445 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A two day seminar on the automated chemical synthesis of peptides and DNA fragments was scheduled for 14 and 15 February at the Institute of Molecular Biology of the Academy of Sciences of the U.S.S.R. in Moscow. The original plan called for lectures and workshops on DNA and peptide synthesis. ...
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    URL: http://dx.doi.org/10.1038/nbt0584-445
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  • 10
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    Tissue Culture Regeneration of Plants in Zea diploperennis , a Close Relative of Corn (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 455-458 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] High frequency and reliable plant regeneration from somatic cells of Zea mays is the key step in allowing the tools of soma-clonal variation, somatic cell hybridization, and recombinant DNA to be used in the development of improved breeding lines. This communication describes high frequency plant ...
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    URL: http://dx.doi.org/10.1038/nbt0584-455
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  • 11
    Electronic Resource
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    Biotech Europe 84, Wembley, U.K. (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 473-473 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Visiting Biotech 84 in London? Some of the stands and products worth seeing include: The micro-controlled Digital Dilute 9200 from Brinkmann Instruments functions as a diluter, dispenser, automatic pipette, sample distributor, and titrator. It comes equipped with two precision glass syringes (the ...
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    URL: http://dx.doi.org/10.1038/nbt0584-473
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  • 12
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    Solving Regional Development Problems with Biotech: Essential Issues (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 287-287 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] City, state, county, and national programs to revitalize economies through biotechnology development have sprung up throughout the world over the past few years. Experience with these programs has revealed that governments are rarely well equipped to understand the complexity of sponsoring ...
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    URL: http://dx.doi.org/10.1038/nbt0484-287
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  • 13
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    Flourishing Not Easy, German Company Finds (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 292-296 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] HAMBURG, West Germany—Despite their government's declared commitment to biotechnology (See page 291), German scientists who would like to be commercial biotechnologists have found the road to starting a company strewn with obstacles. Take Biosyntech, for example. Hubert Koester of the ...
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    URL: http://dx.doi.org/10.1038/nbt0484-292
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  • 14
    Electronic Resource
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    Baxter Breeds Biotech Executives (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 303-303 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—Although the road to becoming chief executive of a biotech start-up company can be long and indirect, a recent informal survey reveals that a surprising number of these CEOs have put in time at one place: Baxter Travenol Laboratories (Deerfield, IL). Baxter alumni that ...
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  • 15
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    Biotechnology: The Regulatory Revolution (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 342-342 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Regulatory Affairs Professional Society (RAPS), an organization for regulatory affairs officers from the chemical, pharmaceutical, and medical device industries, sponsored an educational seminar titled “Biotechnology: The Regulatory Revolution” late last year. The seminar focused on ...
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    URL: http://dx.doi.org/10.1038/nbt0484-342
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  • 16
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    1983 Financing for Health Applications Increases over Agriculture (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 332-333 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Previously we assembled and analyzed data on private investment in U.S.-based biotechnology through 19821. The major areas of commercialization of the technologies are human health, agricultural production, chemical processes, and the scientific infrastructure, e.g. laboratory technology and ...
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    URL: http://dx.doi.org/10.1038/nbt0484-332
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  • 17
    Electronic Resource
    Electronic Resource
    Enzyme Membrane Immunoassay (EMIA) (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 349-355 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Homogeneous enzyme membrane immunoassays (EMIAs) have been developed for thyroxine (T4) and human immuno-globulin G (IgG). Liposomes tagged with T4 and containing alkaline phosphatase were used as a model system for optimization of (a) liposome membrane attack in the presence of T4 antiserum and ...
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    URL: http://dx.doi.org/10.1038/nbt0484-349
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  • 18
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    New Viral Weapons Against Plant Infections (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 202-268 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Unlike the negative feedback operating in so many biological systems, that which a columnist receives from readers is invariably positive. While people respond to topics they find interesting, they ignore boring ones. And when there is a torrent of positive feedback, as followed my recent ...
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    URL: http://dx.doi.org/10.1038/nbt0384-202
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  • 19
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    R&D Limited Partnerships May Be Declining, IBA Meeting Told (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 210-212 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] FORT LAUDERDALE, Florida– R&D limited partnerships may be declining in popularity as a funding mechanism for biotechnology companies, but short term commercial debt may be on the increase. Murray Robinson, chief financial officer of Agri-genetics Corp. (Boulder, CO), told a gathering of ...
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    URL: http://dx.doi.org/10.1038/nbt0384-210
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  • 20
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    International Competition Spurs Commercial Technology (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 232-239 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The 1984 Office of Technology Assessment (OTA) report, Commercial Biotechnology: An International Analysis, is likely to be turned to eagerly as a source of information by many people with diverse interests in biotechnology. Legislators, policy-makers, scientists, corporate officials, educators, ...
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    URL: http://dx.doi.org/10.1038/nbt0384-232
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  • 21
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    A Bacteriophage λ Cohesive Ends ( cos ) DNA Fragment Enhances the Fitness of Plasmid-Containing Bacteria Growing in Energy-Limited Chemostats (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 251-254 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Evidence is presented showing that the set of broad-range cloning pSa plasmids are stably maintained in Escherichia coli. Cells containing these plasmids are generally less fit in glucose-limited chemostat cultures than plasmid-free cells. However, the insertion of a λ cos-containing DNA ...
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    URL: http://dx.doi.org/10.1038/nbt0384-251
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  • 22
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    The Microbiology Laboratory (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 265-267 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The American Society for Microbiology will meet in St. Louis this month, and many product lines that will be on display—including fume hoods for tissue culture preparations, incubators that provide the necessary environment for cell growth, freezers and water baths, centrifuges, and a variety ...
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  • 23
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    Researchers Seeking New Uses for Lignin (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 111-112 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] GOLDEN, Colorado—New applications are in the works for lignin, the major phenolic component of wood that is most difficult to convert into useful and valuable products, according to a report that the Solar Energy Research Institute (SERI), located here, plans to issue this spring. Industrial ...
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    URL: http://dx.doi.org/10.1038/nbt0284-111
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  • 24
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    Biological Replacement Parts (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 130-137 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Replacing a damaged human organ with an artificial but living part sounds like fantasy. Yet, like many fantastic ideas, it is coming closer to reality thanks to biotechnology. No single dramatic breakthrough has occurred; instead, biological replacement parts and bio-artificial organs are the ...
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  • 25
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    Anaerobic Waste Water Treatment (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 143-146 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Anaerobic waste water treatment kept the attention of almost 300 participants from 21 countries in Noordwijkerhout, Netherlands on 23–25 November. The meeting—celebrating the fifth anniversary of the Netherlands Biotechnological Society—was centered around 86 poster presentations ...
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  • 26
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    Expression of a β-Lactamase Preproinsulin Fusion Protein in Escherichia Coli (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 165-168 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The level of expression of a β-lactamase human preproinsulin fusion protein1 in Escherichia coli was increased by plasmid and host manipulations. The initial expression level (0.01% of total protein) was increased two- to three-fold by replacing the p-lactamase promoter with two strong ...
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  • 27
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    Enhancers and other Regulators of Eukaryotic Gene Expression: A First Account (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 173-173 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Enhancers and Eukaryotic Gene Expression. Edited by Yakov Gluzman and Thomas Shenk. Pp. 218. ISBN 0-87969-161-1. (Current Communications in Molecular Biology, Cold Spring Harbor Laboratory: 1983) $27.00. In multicellular organisms, different sets of genes are switched on in different ...
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  • 28
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    Analytical Chemistry, Microscopy, and Image Analysis (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 176-178 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The annual Pittsburgh Conference features exhibitors offering products applicable to the field of analytical chemistry, including chromatography equipment, spectrometers, chemicals, and gases. This month, the new products section describes examples of these products as well as featuring microscopes ...
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  • 29
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    Do We Need a Special Patent Law for Biological Inventions? (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 192-192 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In 1980 the U.S. Supreme Court held, 5–4, that a living organism could be patented as a “manufacture” or “composition of matter” if it satisfied the other requirements of the patent laws. While this decision was a milestone for the biotechnology industry, it should not ...
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  • 30
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    The Dangers of Nitro Compounds (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1005-1005 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: In their article (BIO/TECHNOLOGY 2:805, 1984) entitled “Chemical and Bacterial Pretreatment of Lignocellulosic Material to Increase Ruminant Digestibility,” Drs. Kerr, Windham, and Benner report that pretreatment with nitric acid is the method of choice for increasing ...
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    URL: http://dx.doi.org/10.1038/nbt1284-1005b
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  • 31
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    RAC Rejects Rifkin's Gene Transfer Ban (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1012-1012 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BETHESDA, Md.—This fall's meeting of the Recombinant DNA Advisory Committee (RAC) yielded few surprises but more than a little bit of heated discussion. Once again, Jeremy Rifkin of the Foundation on Economic Trends (Washington, D.C.) was at the forefront. Speaking with Michael W. Fox of the ...
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    URL: http://dx.doi.org/10.1038/nbt1284-1012
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  • 32
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    Management Shifts Abound in Plant Genetics (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1017-1017 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Although high turnover and revised corporate strategies are endemic in developing industries, the number of such changes in plant genetic engineering companies over the past year has been unusual. Some experts view this as a sign that the field is maturing, some that original ...
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  • 33
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    Time to Educate Legislators and Voters (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1000-1000 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] As biotechnology enters the marketplace, it leaves the relatively cloistered environment of the research laboratory and comes into full contact with society. The future of this promising area of enterprise will be determined by the ability of the industry to come to terms with this collision of ...
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  • 34
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    Chromatographic Removal of Pyrogens (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1035-1038 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Endotoxins are toxic lipopoly-saccharides that are released from the cell wall of gram negative bacteria upon cytolysis. Endotoxins are pyrogenic, that is, they produce a rise in temperature in man or other mammals. Even if the bacteria are killed, the endotoxins remain pyrogenic and thus their ...
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    Use of Synchronous Site-Specific Recombination in Vivo to Regulate Gene Expression (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1045-1049 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We have constructed a plasmid that carries the gene for T4 DNA ligase, the gene II promoter from bacteriophage m13, and analogues of attL and attR. attL and attR are substrates for site specific recombination catalyzed by the Int and Xis proteins of bacteriophage λ. The elements on this ...
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    Current Thoughts on Microbial Fuel Cells (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 921-921 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Electric currents of more than 100 mA, generated recently over several hours by bacteria in a London laboratory, could be the signals which now convince even the greatest skeptics that microbial fuel cells are a practical proposition. If so, all credit to Gerard Delaney, Peter Bennetto, and their ...
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    Irish Eyes Shine on Biotech (1984)
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    Nature biotechnology 2 (1984), S. 929-929 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Ireland is setting up a $10 million fund to create four centers of biotech excellence. The “National Program for Biotechnology Research,” which is still in draft form and awaiting government approval, reaffirms Ireland's emphasis on attracting biotech to the ...
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    Chronicle (1984)
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    Nature biotechnology 2 (1984), S. 930-930 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The first reported expression of HTLV-III virus envelope protein was achieved by Centocor (Malvern, PA). Michael Wall, Centocor's chairman, says the protein is immunoreactive with antibodies in the blood of patients suffering from acquired immunodeficiency syndrome, so the company intends to ...
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    Charged Up Over Biochemical Fuel Cells (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 935-936 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MUNICH—Apart from generating electricity (or serving as ultrasensitive detectors), biochemical fuel cells may hold great potential for producing commercially interesting, high-value substances. That forecast was made recently by a group led by Colja Laane of the Agricultural University at ...
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    Improving Morels via Genetic Engineering (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 936-936 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MUNICH—The possible genetic engineering of morels was a topic of interest at September's biotechnology conference here. Because fruiting bodies of these ascomycetes had not been produced in the laboratory until very recently, they have never been manufactured commercially or subjected to any ...
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    Big Resource for Small Computers (1984)
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    Nature biotechnology 2 (1984), S. 945-952 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Samuel Johnson said (or so Boswell reports) that “Knowledge is of two kinds. We know a subject ourselves, or we know where we can find information upon it.” As the wave of information rises, it becomes more and more difficult to know even where to start in the search for published ...
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    New Products (1984)
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    Nature biotechnology 2 (1984), S. 985-989 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Isolab Inc. now offers three formats for its Quik-Sep® prepackaged Sephadex® G-25 cloumns. The QS-2A features a 2.4 cm bed height, with 5 ml total column volume. The QS-2B format, routinely used for desalting applications, is packed to a bed height of 5.0 cm with 6.5 ml total column volume. ...
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    Patenting Biotechnology (1984)
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    Nature biotechnology 2 (1984), S. 991-992 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biotechnology and the Law. By Iver P. Cooper. Pp. 575. ISBN 0-87632-311-5 (Clark Boardman Company, Ltd, New York: 1983). $75.00. Increased awareness of the existing and potential value of biotechnology has directed attention to strategies for obtaining effective proprietary protection of ...
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    FDA Loosens Restraints on Cell Substrates (1984)
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    Nature biotechnology 2 (1984), S. 842-842 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] BETHESDA, Maryland—The U.S. Food and Drug Administration (FDA) has issued new guidelines that should smooth the regulatory process for biologicals produced by continuous cell lines. Emphasizing that its Points to Consider in the Characterization of Cell Lines Used to Produce Biologicals are ...
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    AGS Head Calls Frost Bug Ruling ‘Farfetched’ (1984)
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    Nature biotechnology 2 (1984), S. 12-13 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] GREENWICH, Connecticut—The head of Advanced Genetic Sciences (AGS) doesn't think much of the U.S. Environmental Protection Agency's recent declaration that a new bacteri um designed to prevent frost damage in plants can be classified as a pesti cide and therefore comes under the agency's ...
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    SBIR Grants Going to Biotech (1984)
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    Nature biotechnology 2 (1984), S. 22-25 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Biotech companies in the United States are taking advantage of new federal funding. Through the recently implemented Small Business Innovation Research program (SBIR), more than 40 bio-technology concerns have received phase I funding on the order of $25,000-50,000 for ...
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    The International Centre for Genetic Engineering and Biotechnology (1984)
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    Nature biotechnology 2 (1984), S. 55-59 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The rapid development of biotechnology in the ad vanced industrial nations in recent years has, like other new technologies that preceded it, called attention once again to the disparity between the haves and have-nots, the North-South gap, or howev er one wishes to refer to the lack of equity in ...
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    Cloning and Expression of Antibiotic Production Genes (1984)
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    Nature biotechnology 2 (1984), S. 63-72 
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    Notes: [Auszug] Recent advances in the molecular genetics of antibiotic biosynthesis open new perspectives for improvement of antibiotic production. Genes coding for enzymes involved in antibiotic biosynthesis appear to be clustered on the DNA of antibiotic producers. Both low and high copy plasmids and phage ...
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    Monsanto Supports Oligosaccharide Research (1984)
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    Nature biotechnology 2 (1984), S. 8-10 
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    Notes: [Auszug] OXFORD, England—Monsanto Com pany (St. Louis, MO) will underwrite research on oligosaccharides at the ancient university here. The deal, for £1.2 million ($1.8 million) over five years, will support work in the uni versity's biochemistry department on the isolation, structure, ...
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    Analysts Predicting Biotech Stock Rises for 1984 (1984)
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    Nature biotechnology 2 (1984), S. 16-20 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—The year 1983 had its ups and downs for bio-tech stocks, but industry analysts are anticipating a successful 1984. Peak prices reached last summer dropped off as much as a third or more by the fall (see chart), and the BIO/TECHNOLOGY Stock Index of Specialty Firms has ...
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    Hybridomas Offer New Hope for Controlling Animal Parasites (1984)
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    Nature biotechnology 2 (1984), S. 22-22 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] BELTSVILLE, Maryland—Parasitic diseases such as coccidiosis and try panosomiasis afflict billions of domes tic animals worldwide, and until re cently the only hope for controlling these plagues was massive doses of antibiotics in feed. Monoclonal anti bodies, however, are providing re ...
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    Chromatographic Gel Media for Large Scale Protein Purification (1984)
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    Nature biotechnology 2 (1984), S. 41-55 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Urease was the first enzyme to be isolated in a crystalline form by Sumner in 19261, and subsequent work on its chemical composition and degradability by proteolytic enzymes led Sumner to the (then) controversial conclusion that enzymes are proteins. Ever since, it has been recognized that ...
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    Plant Viruses and Subviral Agents (1984)
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    Nature biotechnology 2 (1984), S. 86-86 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Plant Infectious Agents: Viruses, Viroids, Virusoids, and Satellites. H. D. Robertson H , S. H. Howell S H, M. Zaitlin M, and R. L. Malmberg R L Pp. 230. ISBN 0-87969-159-X. (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY: 1983) $23(U.S.), $27.60(Outside U.S.). Plant ...
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    Oncogenes, Inositol Lipids and Cellular Proliferation (1984)
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    Nature biotechnology 2 (1984), S. 541-546 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Cells within the body are normally under careful control to ensure that cell growth occurs only when required either for development or for body maintenance. Quiescent cells can be stimulated to grow by a variety of growth factors which act on cell surface receptors to initiate DNA synthesis ...
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    MCAs, Separations, and Biotechnology's Future (1984)
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    Nature biotechnology 2 (1984), S. 555-557 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Keynote lectures provide a speaker with a chance to synthesize, prophesize, and even fantasize. Werner Arber (University of Basel, Switzerland) asserted “There is nearly no limitation to potentially interesting applications for biotechnology.”However, he went on to say that we still ...
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    A Clever Twist on Conventional Microbiology (1984)
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    Nature biotechnology 2 (1984), S. 560-560 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The novelty-generating activity we call science, coupled with the profit motive of capitalism, should ensure that exploitable discoveries are recognized quickly, and then be harnessed to both immediate and unforeseen practical ends. Witness the staggering variety of uses now being found for ...
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    Cohen-Boyer: A Brief History (1984)
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    Nature biotechnology 2 (1984), S. 387-387 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The Cohen-Boyer patent has become a landmark in the genetic engineering industry, albeit a landmark of uncertain fate. The volatile history of the patent has created confusion about both the scope and nature of its claims, and it probably will take several years and millions of dollars to resolve ...
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    Stock Prices of Selected Biotechnology Speciality Firms (1984)
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    Nature biotechnology 2 (1984), S. 403-403 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Price March 15 Price April 15 Percent Change 52 Week Hi-Low Market Capitalization in $ millions (stock price × number of shares outstanding) Companies Emphasizing Recombinant DNA Technology Advanced Genetic Sciences 53/4 43/4 −17 143/4–31/4 52 ...
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    Microbial Insect Control: Using Bugs to Kill Bugs (1984)
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    Nature biotechnology 2 (1984), S. 408-419 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The larva of the yellow fever mosquito, Aedes aegypti, adrift in a lethal cloud of Tolypocladium cylindrosporum, a fungal pathogen. Microorganisms can devastate insects as dramatically as chemicals can. Not just fungi, but also viruses and especially bacteria offer new hope for biological control ...
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    Energy from Biomass and Wastes (1984)
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    Nature biotechnology 2 (1984), S. 434-440 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The effort to develop and apply technology for fuels and energy from biomass and wastes overcame a serious obstacle in 1983—it grew despite reductions in financial support. Presentations at the eighth technical symposium on Energy from Biomass and Wastes, sponsored by the Institute of Gas ...
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    Novel Bioreactor Systems and Their Applications (1984)
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    Nature biotechnology 2 (1984), S. 447-453 
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    Notes: [Auszug] New sophisticated bioreactor designs with unique performance characteristics will play a vital role in the economic manufacture of useful biotechnological products from natural and genetically modified cell systems of microbial, mammalian and plant origin. In this paper we summarize the basic ...
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    Genetic Engineering and Biotechnology Firms (1984)
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    Nature biotechnology 2 (1984), S. 475-475 
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    Notes: [Auszug] Genetic Engineering and Biotechnology Firms Worldwide Directory 1983/1984. Edited by M. Sittig and R. Noyes. Pp. 427. (Sittig and Noyes, Kingston, N.J.: 1983) $177 For a relatively new industry, biotechnology is remarkably well served with information sources. Few researchers or managers ...
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    Putting Sticky Bugs to Work (1984)
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    Nature biotechnology 2 (1984), S. 288-288 
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    Notes: [Auszug] Given the possibility of genetically engineering “a one micron scientist” to study bacterial adhesion at close range, should he/she be a microbiologist or a physical chemist? Such was one of the less serious questions considered in Berlin recently during a Dahlem Conference at which ...
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    Biotechnology Taking Root in West Germany (1984)
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    Nature biotechnology 2 (1984), S. 291-292 
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    Notes: [Auszug] BONN, West Germany—Biotechnology is at last taking root in West Germany. Academics are coming to see biology as an industrial activity, while the big industrial combines increasingly seek collaborative partnerships with centers of excellence in their own country. Government spending on ...
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    Construction of a Live Oral Cholera Vaccine (1984)
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    Nature biotechnology 2 (1984), S. 334-334 
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    Notes: [Auszug] One of the great promises offered by recombinant gene technology is the production of new and more effective vaccines1. In this issue of BIO/TECHNOLOGY, James Kaper and his colleagues at the Center for Vaccine Development (CVD, University of Maryland School of Medicine, Baltimore) describe the ...
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    Biotechnology Trade with Japan (1984)
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    Nature biotechnology 2 (1984), S. 327-332 
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    Notes: [Auszug] Trade in biotechnology products is just beginning as the products start to reach the international marketplace. Even firms not planning to manufacture and market specific products should consider foreign markets for biotechnology products, and the Japanese market certainly will be a key factor in ...
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    Faseb and Fermentation Products (1984)
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    Nature biotechnology 2 (1984), S. 361-363 
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    Notes: [Auszug] April brings the Federations of American Societies for Experimental Biology's (FASEB) annual meeting. A great variety of manufacturers will exhibit their wares at the meeting, and many of the products that will be on display are featured below. In addition, a range of fermentation products are ...
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    The Worldwide Revival of Alcohol Fuels (1984)
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    Nature biotechnology 2 (1984), S. 364-366 
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    Notes: [Auszug] Alcohol Fuels: Options for Developing Countries. Report of an ad hoc panel of the Advisory Committee on Technology Innovation, Board of Science and Technology for International Development. Pp. 109. ISBN 0-309-03386-1 (National Academy Press, Washington, D.C.: 1983). $8.95 The current ...
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    Five Industrial Imperatives (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 200-200 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Readers may benefit themselves and their fields if they consider several imperatives for US biotechnology over the coming year. •Environmental concerns, particularly issues regarding the microbial fitness of future products and known, wild-type pathogens, should be elevated to become strong ...
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    ‘Ice Minus’ Talks Cancelled After Court Action (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 204-207 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.–Legal action against the Recombinant DNA Advisory Committee (RAC) has once again delayed the plans of Advanced Genetic Sciences (AGS) for moving ahead with field testing the genetically engineered strain of Pseudomonas syringae that the company hopes will prevent frost damage ...
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  • 71
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    Interferon on Trial (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 214-228 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Top: Photomicrograph of recombinant alpha-A interferon crystals. Bottom: Record from clinical trial of Hoffmann-La Roche's recombinant alpha-A interferon, showing a patient's blood levels of interferon. This is a time of decision about interferon, the collective name for one group of substances ...
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  • 72
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    Current and Experimental Methods of Rapid Microbial Identification (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 243-248 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Current techniques in the clinical microbiology laboratory, such as radioimmuno-assays (RIA) and enzyme linked immunosorbent assays (ELISA), are examined critically. A conceptually different, still experimental technique, which we believe may alter clinical microbiology testing substantially, is ...
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  • 73
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    Bacterial Fitness and Genetic Engineering (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 239-239 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Genetic engineering companies may soon find it necessary to hire molecular geneticists with expertise in the area of microbial evolution. The reason for this lies in the growing interest in the fitness and adaptation of genetically engineered microorganisms, both in the laboratory and following ...
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  • 74
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    Analysis of Resident and Transformant Plasmids in Bacillus Megaterium (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 254-259 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Bacillus megaterium has been used industrially to produce vitamins, amino acids and proteins. Recently, our laboratory isolated a generalized transducing bacteriophage for this species, and several loci have been mapped. To further study strain QM B1551, we have now analyzed its resident plasmids ...
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  • 75
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    Biocon Scientists Produce Heat-Stable Enzyme from B. Subtilis (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 112-115 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] DUBLIN, Ireland—Researchers here claim that the gene that codes for production of a commercially important, heat-stable form of the enzyme α-amylase has for the first time been cloned and introduced directly into Bacillus subtilis, the bacterial workhorse used widely to produce enzymes ...
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    Industry should Collaborate on Scale up Problems (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 109-109 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Although the laboratory end of biotechnology's stream of development enjoys the lion's share of attention, the scale-up stage of process development determines the feasibility of actually manufacturing a product. The sheer cost in time, equipment, and labor of scaling up presents a roadblock to the ...
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  • 77
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    Reports of its Death were Exaggerated (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1005-1005 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: I am writing in reference to your article entitled “Phillips: Wildcatting in Biotech” (BIO/TECHNOLOGY 2:853, 1984). The article implied that the Bartlesville Energy Technology Center (BETC), including its capabilities in microbial enhanced oil recovery, is now defunct. I ...
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  • 78
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    Firms Seek to Score on Protein Analysis (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1011-1012 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] ROCKVILLE, Md.—Two new companies are seeking to commercialize 2-dimensional gel electrophoresis, a separations technology that has existed for close to a decade. Bioresources Laboratories, the for-profit company started here by the American Type Culture Collection (ATCC) a year-and-a-half ...
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  • 79
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    Canada Contemplates Deliberate Release (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1016-1016 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TORONTO, Ont.—The Canadian Environmental Law Research Foundation (CELRF) has proposed creation of a National Biotechnology Commission to study, assess, and certify all new life forms intended for release into the environment. Such a commission would also administer a nationwide information ...
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  • 80
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    Chronicle (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1021-1021 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] New joint ventures continue to be the rage in biotechnology: • Celltech (Slough, U.K.) has set up its second joint venture company, this one a 50:50 owned project with Air Products Ltd., to be called Apcel. The firm, originally capitalized with £3.2 million , will apply genetic ...
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  • 81
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    How About Contract Research? (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1029-1033 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Make-or-buy is a common and crucial dilemma facing corporate planners throughout the high technology industries—is it better to solve an R&D problem in-house or would it be more economical to deal with it through a joint venture or contract research? While executives are often inherently ...
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  • 82
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    IBA Listens to Calls for Regulation (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1015-1015 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SAN FRANCISCO—Public issues dominated the Third Annual Meeting of the Industrial Biotechnology Association: patent rights, press coverage, and, above all, regulation. Feeling among the hundred-odd industry executives and observers here ran heavily in favor of even-handed federal regulation, ...
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  • 83
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    Cornell Gets $22 Million for Biotech Center (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1017-1018 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] ITHACA, N.Y.—Cornell University held its second annual biotechnology symposium this fall amid excitement surrounding new funding for biotech research here. At a trustees meeting a week earlier, New York Governor Mario Cuomo announced that he will recommend the appropriation of $22 ...
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  • 84
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    Microcomputer Tools for Biotechnology (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 1022-1028 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The newest of the new biology is an information science. It seeks to discover, codify, and interpret the information stored in nucleic acids, expressed in polypeptides. The volume is vast; interpreting it would be impossible without computer help. For about a decade, that help has been available to ...
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  • 85
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    Molecular Biology and Ecology of Diazotrophs Associated with Non-Leguminous Plants (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 967-978 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Only some prokaryotes have evolved the genetic information for nitrogen fixation. These prokaryotes, when associated with plants, can contribute to their growth by providing reduced nitrogen (ammonia). The genetics of nitrogen fixation was elucidated in Klebsietta pneumoniae, where it was found ...
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  • 86
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    IML Introduces Interferon Product for Cattle (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 841-841 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] HOUSTON, Tex.—Interferon is now being marketed in the United States as an orally administered therapeutic agent—not to people, but to cattle. Immuno Modulators Laboratories (IML), located here, recently received Food and Drug Administration approval to sell its alpha interferon product, ...
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    Anti-Idiotypic Antibodies: A Safer Way to Immunize Against Aids? (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 923-927 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BOSTON—Vaccination without direct exposure to any viral nucleic acid, protein, or peptide could become possible using anti-idiotypic antibodies. Researchers here are developing these substances as immunizing agents for two classes of human T-cell leukemia viruses (HTLV): HTLV-I, which causes ...
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    Monitoring Fermentation by Heat (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 936-936 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MUNICH—Prospects for monitoring biomass production by measuring the heat generated during microbial growth were outlined at the biotech meeting here by Urs von Stockar from the Institute de Génie Chimique, EPFL-Ecublens, (Lausanne, Switzerland), and Ian Marison from the University of ...
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  • 89
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    Announcements (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 903-903 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NOVEMBER MEETINGS Nov. 1–2. International Conference on Investment in Biotechnology. London, U.K. Info: Helen Raquet, Oyez Scientific and Technical Services, Bath House (3rd Floor), 56 Hoiborn Viaduct, London EC1, U.K. Nov. 8–10. The 1984 High-Technology Route to Virus Vaccines. ...
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    More Money, Options for SBIR Grants (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 847-847 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] FORT COLLINS, Colo.—Federal funding agencies are gearing up to solicit and fund record levels of Small Business Innovation Research (SBIR) grants. Under Congressional mandate, the share of federal R&D money allocated to the SBIR program will more than double over the next two years. ...
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    Chronicle (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 849-849 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] At presstime, University Genetics' president, Alan G. Walton, reported that UGEN will acquire only 55 percent of Trans World Genetics, instead of the 90 percent reported in a news story in this issue. Walton said UGEN has set up a new 100 percent-owned subsidiary, Applied Animal Genetics (Napa, ...
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    U.K. Starts Cell Bank (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 850-850 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] PORTON DOWN, Wiltshire, U.K.— A National Collection of Animal Cell Cultures (NCACC), set up with funds from the U.K. Department of Trade and Industry, has opened at the Centre for Applied Microbiology and Research. The first of its sort in Europe, the collection was created because of ...
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    Conservation of T-DNA in Plants Regenerated from Hairy Root Cultures (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 73-76 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] T1-plants (first generation of transformed plants) regenerated from hairy root culture lines synthesized the same opines and carried T-DNA with the same restriction pattern as the parental line. Opine synthesis segregated in the progeny of T1-plants (T2-plants), Two opine-positive T2-plants had ...
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    A Polypeptide Fusion Designed for the Purification of Recombinant Proteins (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 76-81 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Recombinant DNA technology was used to produce human urogastrone with a C-terminal polyarginine fusion. This peptide fusion formed the basis of a two-step ion exchange purification that gave 64mg of urogastrone at 〉95% purity with 44% yield. In the first step, a substantial purification was ...
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    Recombinant DNA Technology (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 86-87 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Methods in Enzymology Volumes 100 and 101; Recombinant DNA Parts B and C. S. P. Colowick S P, R. Wu R. Pp. 540. ISBN 012-182-000-9 (Academic Press, Inc. Publishers, New York, NY: 1983) $69.50. Books entitled “Recombinant DNA” have received considerable interest lately. ...
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    Functional morphology of locomotion in Derocheilocaris typica (Crustacea, Mystacocarida) (1982)
    Springer
    Zoomorphology 100 (1982), S. 1-10 
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    ISSN: 1432-234X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The crustacean class Mystacocarida is restricted to the interstitial marine sand environment. A cinemicrographic analysis of the functional morphology of locomotion in the mystacocarid D. typica was undertaken to demonstrate how this species progresses through the interstitial spaces. Locomotion is completely dependent on the presence of dorsal and ventral substrates. The biramous second antennae and mandibles are the force-generating appendages. During a locomotory cycle, the exopods of the second antennae and mandibles are directed dorsolaterally against a dorsal substrate. This creates a downward force enabling the endopods to gain purchase on the ventral substrate. The second antennae and mandibles undergo coordinated cyclic movements. Each cycle results in two power and two recovery strokes. The animals undergo approximately 4 complete cycles per second. The calculated maximum rate of locomotion is 420 μm/s. The measured rate under test conditions is 250 μm/s. A turning-escape reaction in response to air bubbles and other factors results in a 180° turn in a confined space within 1.5 s. These data are discussed in relation to the morphological conservatism of mystacocarids, their presumed neotenic origin and their observed migration over a tidal cycle. It is proposed that all crawling interstitial animals will have developed specific mechanisms to increase frictional forces between their locomotory appendages and the surrounding substrate.
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    Fine structure of the ocellus of Sarsia tubulosa (Hydrozoa, Anthomedusae) (1982)
    Springer
    Zoomorphology 100 (1982), S. 11-22 
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    ISSN: 1432-234X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The fine structure of the ocellus of Sarsia tubulosa is described. The ocellar cup is formed of pigment cells and receptor cells. The receptor cells outnumber the pigment cells in almost a 2:1 ratio. Lateral extensions of neighbouring pigment cells enclose a distal region of 2 to 10 receptor cells. The receptor cell body is 5–7 μm in diameter with an apical extension (20–60 μm long) that reaches the ocellar cavity. A cilium (9+2 microtubules) arises from the distal part of the receptor cell. The ciliary membrane forms lateral microvilli. The tips of a number of cilia are swollen into large vesicles forming a “cornea”. The central region of the ocellar cavity contains extracellular electron dense homogeneous material surrounded by swollen ciliary tips and small vesicles. The close apposition between the plasma membrane covering the distal part of adjacent receptor cells as well as the adjacent ciliary shafts suggests the presence of gap junctions. The basal part of each receptor cell forms an axon. The axons of receptor cells form 3 to 4 nerve bundles that join to form the optic nerve. Synapses occur between receptor cell bodies, between axons and receptor cell bodies and among axons.
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    The anal glands of Rhapidostreptus virgator (Diplopoda: Spirostreptidae) (1982)
    Springer
    Zoomorphology 100 (1982), S. 65-73 
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    ISSN: 1432-234X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary In Rhapidostreptus virgator exocrine gland complexes are found in the anal valves of both sexes. Every gland complex consists of about 200 secretory units, each of which is comprised of four cells: two secretory cells, an intermediary cell, and a canal cell. The amount of secretion produced by these glands varies during the intermoult cycle: it is very small in freshly moulted individuals (postmoult phase), at a medial level during the following intermoult phase, and very large in the premoult phase. The secretion may be used to form the excrement clumps and above all to build the moulting chamber.
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    The morphology of amphibian skin vascularization before and after metamorphosis (1982)
    Springer
    Zoomorphology 100 (1982), S. 55-63 
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    ISSN: 1432-234X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The skin vascularization was investigated troughout the ontogenetic development and in adults of two anurans, Rana temporaria and Bufo bufo, and two urodeles, Triturus vulgaris and Triturus cristatus. It was found that, contrary to the urodele larvae, the anuran tadpoles have a very sparse skin vascularization. During the early stages of anuran metamorphosis the skin capillary network becomes dense; later, during skin metamorphosis, a second, venous, network is formed as anastomoses between the subcutaneous vein ramifications. In the urodeles, metamorphosis is not accompanied by any significant morphological changes in the skin vascularization, and a subcutaneous network is not formed. It is suggested that the reduced skin vascularization in anuran tadpoles is an advanced larval character relative to the rich vascularization of the skin in urodele larvae. It is further suggested that anuran tadpoles have a reduced ability to utilize gaseous exchange through the skin. The function of the subcutaneous venous network found in anurans after metamorphosis is obscure; experiments indicate a vasomotor regulation which is neither adrenergic nor cholinergic.
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    The larval morphology of the marine bryozoan Bowerbankia gracilis (Ctenostomata: Vesicularioidea) (1982)
    Springer
    Zoomorphology 100 (1982), S. 23-54 
    Details
    ISSN: 1432-234X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The larval morphology of the marine bryozoan Bowerbankia gracilis has been investigated by light and electron microscopy. The barrel-shaped larva (200 μm long and 150 μm in diameter) is light yellow without any apparent eyespots, although it is positively phototactic during its brief free-swimming existence. The primary morphological characteristics of the larva are: (1) a large corona that forms most of the larval surface, (2) a small apical disc without blastemas, (3) a deep pallial sinus lined by an extensive pallial epithelium, (4) an internal sac without regional specializations, and (5) a polypide rudiment in the oral hemisphere. This organization is characteristic of larvae of the ctenostome superfamily Vesicularioidea, and differs radically from the organization of all other bryozoan larvae examined. The major morphological differences occur in the size and organization of the apical disc, the pallial epithelium, and the internal sac. In most bryozoans, these regions of the larval epithelium represent rudiments of the polypide and the body wall epidermis of the ancestrula. The oral polypide rudiment, the extensive pallial epithelium, and the reduced internal sac in vesicularioid larvae indicate that their pattern of metamorphosis also differs radically from the metamorphoses of other bryozoans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00312198
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