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  • 1990-1994  (441)
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  • 1
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    Springer
    Computing 51 (1993), S. 271-292 
    ISSN: 1436-5057
    Keywords: 65N15 ; 65N99 ; 35A40 ; Box method ; boundary value problem ; finite volume method ; variational formulation ; stability ; error bounds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Box-Methoden (Finite-Volumen-Methoden) sind verbreitete Verfahren zur Lösung physikalischer Erhaltungsgleichungen, insbesondere in der Strömungsmechanik. In dieser Arbeit werden zwei Methoden für elliptische Differentialgleichungen untersucht, die Diagonal-Boxen und die Schwerpunkt-Boxen. Da die Box-Methoden im Sinne von Petrov-Galerkin-Verfahren interpretiert werden können, erhält man vergleichbar zur Finiten-Element-Methode eine variationsrechnerische Stabilitäts- und Fehleranalyse. Damit werdenO(h)- undO(h 2)-Fehlerabschätzungen hergeleitet. Lokale Eigenwertprobleme führen zu Stabilitätsaussagen. Allerdings ergibt sich eine Abhängigkeit von der Anzahl und Art gestörter Vierecke. Insbesondere die Diagonal-Boxen sind anfällig für lokale Störungen.
    Notes: Abstract Box schemes (finite volume methods) are widely used in fluiddynamics, especially for the solution of conservation laws. In this paper two box-schemes for elliptic equations are analysed with respect to quadrilateral meshes. Using a variational formulation, we gain stability theorems for two different box methods, namely the so-called diagonal boxes and the centre boxes. The analysis is based on an elementwise eigenvalue problem. Stability can only be guaranteed under additional assumptions on the geometry of the quadrilaterals. For the diagonal boxes unsuitable elements can lead to global instabilities. The centre boxes are more robust and differ not so much from the finite element approach. In the stable case, convergence results up to second order are proved with well-known techniques.
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  • 2
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    European journal of nutrition 29 (1990), S. 219-228 
    ISSN: 1436-6215
    Keywords: Vitamin K ; Menadion ; Menadiol ; Bioverfügbarkeit ; Stabilität ; Geflügel ; vitamin K ; menadione ; menadiol ; bioavailability ; stability ; poultry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary A bioassay of vitamin K is described, based on the prothrombin clotting time of 3-week-old, vitamin-K-depleted, and cumatetralyl-sensitized male broiler chicks, using a homologous thrombokinase preparation. With this test it could be shown that the diacetate and dibutyrate esters of menadiol are vitamin-K-active. The bioactivity of menadione from these menadiolesters amounted to about 70 % of the standard menadione from a coated menadione sodium bisulfite (Dohyfral). Menadiol seems to be temperature-resistant under such conditions, whereby two uncoated MSB preparations lost about 60 % of their activity.
    Notes: Zusammenfassung In einem biologischen Testverfahren an Cumatetralyl sensibilisierten Küken konnte in 3 Versuchen anhand des Parameters Thromboplastinzeit mit homologer Thrombokinase gezeigt werden, da\ Menadioldiacetat und Menadioldibutyrat Vitamin-K-wirksam sind. Die biologische Wirksamkeit von Menadion aus diesen Menadiolestern betrug ca. 70 % der Menadionaktivität aus gecoatetem Menadionbisulfit (Dohyfral®). Im Gegensatz zu 2 ungeschützten MSB-Präparationen, welche bei Wärmebelastung ca. 60 % ihrer ursprünglichen Wirkung verloren, waren die Menadiolester temperaturstabil.
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  • 3
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    OR spectrum 16 (1994), S. 47-52 
    ISSN: 1436-6304
    Keywords: Vector optimization ; approximately efficient solutions ; stability ; Vektoroptimierung ; Näherungslösungen ; Stabilität
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Description / Table of Contents: Zusammenfassung Wir führen ein Konzept für Näherungslösungen in der Vektoroptimierung ein und vergleichen dieses mit einem neuen Konzept aus [8]. Weiterhin untersuchen wir Beziehungen zwischen der Menge der Näherungslösungen eines Vektoroptimierungsproblems und den Näherungslösungen eines entsprechenden parametrischen Ersatzproblems. Schließlich beweisen wir Stabilitätseigenschaften des skalaren Ersatzproblems.
    Notes: Abstract We introduce a concept for approximately efficient solutions in vector optimization and compare it with another recent concept given in [8]. Further, we study relations between the set of approximately efficient solutions of a vector optimization problem and the approximate solutions of a corresponding parametric surrogate optimization problem. Finally, we prove stability properties for the scalar surrogate problem.
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  • 4
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    Mathematical programming 47 (1990), S. 117-141 
    ISSN: 1436-4646
    Keywords: Bifurcation ; singularity ; parametric programming ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract The structure of solutions to the nonlinear parametric programming problem with a one dimensional parameter is analyzed in terms of the bifurcation behavior of the curves of critical points and the persistence of minima along these curves. Changes in the structure of the solution occur at singularities of a nonlinear system of equations motivated by the Fritz John first-order necessary conditions. It has been shown that these singularities may be completely partitioned into seven distinct classes based upon the violation of one or more of the following: a complementarity condition, a constraint qualification, and the nonsingularity of the Hessian of the Lagrangian on a tangent space. To apply classical bifurcation techniques to these singularities, a further subdivision of each case is necessary. The structure of curves of critical points near singularities of lowest (zero) codimension within each case is analyzed, as well as the persistence of minima along curves emanating from these singularities. Bifurcation behavior is also investigated or discussed for many of the subcases giving rise to a codimension one singularity.
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  • 5
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    Mathematical programming 54 (1992), S. 57-67 
    ISSN: 1436-4646
    Keywords: Matchings ; stability ; extreme points ; polytope
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract The purpose of this paper is to extend a modified version of a recent result of Vande Vate (1989) which characterizes stable matchings as the extreme points of a certain polytope. Our proofs are simpler and more transparent than those of Vande Vate.
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  • 6
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    Mathematical programming 61 (1993), S. 197-214 
    ISSN: 1436-4646
    Keywords: Epi-convergence ; epi-distance ; stability ; convex optimization ; approximate solutions ; subgradients ; level sets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract We prove that theε-optimal solutions of convex optimization problems are Lipschitz continuous with respect to data perturbations when these are measured in terms of the epi-distance. A similar property is obtained for the distance between the level sets of extended real valued functions. We also show that these properties imply that theε-subgradient mapping is Lipschitz continuous.
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  • 7
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    Computing 44 (1990), S. 187-196 
    ISSN: 1436-5057
    Keywords: 65M10 ; Spectral method ; stability ; stability threshold
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Zur numerischen Lösung einer nichtlinearen Differentialgleichung dritter Ordnung, herrührend aus einem Strömungsproblem bei Gasteilchen, wird ein zeitdiskreter Pseudo-spektral-Algorithmus vorgeschlagen. Stabilität und Konvergenz des neuen Differenzenverfahrens werden analysiert. Numerische Vergleiche mit bestehenden Differenzenschemata sprechen klar zugunsten des neuen Verfahrens.
    Notes: Abstract A time-discrete pseudospectral algorithm is suggested for the numerical solution of a nonlinear third order equation arising in fluidization. The nonlinear stability and convergence of the new scheme are analyzed. Numerical comparisons with available finite-difference methods are also reported which clearly indicate the superiority of the new scheme.
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  • 8
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    Acta biotheoretica 39 (1991), S. 1-14 
    ISSN: 1572-8358
    Keywords: Hematological diseases ; first order partial differential equations ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract To address the possibility that proliferative disorders may originate from interactions between multiple populations of proliferating and maturing cells, we formulate a model for this process as a set of coupled nonlinear first order partial differential equations. Using recent results for the asymptotic behaviour of the solutions to this model, we demonstrate that there exists a region of coupling coefficients, maturation rates, and proliferation rates that will guarantee the stable coexistence of coupled cellular populations. The analysis shows that increases in the coupling between populations may ultimately lead to a loss of stability. Furthermore, the analysis indicates that increases (decreases) in the maturation and/or proliferation rates above (below) critical levels will lead either to instability in the populations or the destruction of one population and the persistence of the other.
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  • 9
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    Journal of intelligent manufacturing 4 (1993), S. 183-198 
    ISSN: 1572-8145
    Keywords: Assembly planning ; subassembly ; liaison graph ; geometric reasoning ; assembly cost ; stability ; partial-order graph
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The distribution of assembly workstations enables assembly operations to be done in parallel, while the multiple routing of parts in flexible assembly systems allows the opportunistic scheduling of assembly operations. This paper presents an assembly planning system, called the Assembly Coplanner, which automatically constructs an assembly partial order and generates a set of assembly instructions from a liaison graph representation of an assembly based on the extraction of preferred subassemblies. Assembly planning in Coplanner is carried out by the co-operation of multiple planning agents, such as the geometric reasoner, the physical reasoner, the resource manager and the plan coordinator, under the constraints of finding a cost-effective assembly plan in a flexible assembly system. The Coplanner identifies spatial parallelism in assembly as a means of constructing temporal parallelism among assembly operations. This is achieved in the following way: (1) the selection of a set of tentative subassemblies by decomposing a liaison graph into a set of subgraphs based on feasibility and difficulty of disassembly; (2) the evaluation of each of the tentative subassemblies in terms of assembly cost represented by subassembly selection indices; and (3) the construction of a hierarchical partial order graph (HPOG) as an assembly plan. A case study applying the Coplanner to a mechanical assembly is illustrated in this paper.
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  • 10
    ISSN: 1572-8900
    Keywords: Chemiluminescence ; oxidation ; stability ; acrylonitrile-butadiene-styrene (ABS) ; ABS/polycarbonate blend
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The thermal oxidative stability of various ABS/PC compounds was studied by means of the chemiluminescence technique. Similarly to pure ABS, Irganox 1076 and Irganox MD 1024 perform as moderate antioxidants in ABS/PC and (ABS/PC + lubricant) blends. Neither Tinuvin 144, Irgaphos 168, nor their mixture affects the durability of the ABS/PC blend. At the same time, (Irgaphos 168 + Tinuvin 144) in combination with Irganoxes was found to provide a noticeable enhancement in durability to the (ABS/PC + lubricant) system. Titanium dioxide pigments by themselves have only a slight influence on the oxidative stability of the ABS/PC blend. Durability of the (ABS/PC + pigment) and (ABS/PC + lubricant) systems was found to be the same and the overall protective effect of Irganox 1076 was similar in both the (ABS/PC + lubricant) and the (ABS/PC + lubricant + pigment) systems. Certain modifiers significantly improve the durability of the ABS/PC compounds, although their function may differ in the systems with and without pigments.
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  • 11
    ISSN: 1572-8900
    Keywords: Chemiluminescence ; oxidation ; stability ; acrylonitrile-butadiene-styrene (ABS)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The influence of lubricants, UV stabilizers, antioxidants, and metal deactivators on the resistance of ABS to thermal oxidation was studied by means of the chemiluminescence technique. Neither of the additives seems to affect significantly the induction period of oxidation. At the same time, the influence of various additives on the oxidation rate constant is remarkably different: the introduction of lubricants and UV stabilizers increases its value, while antioxidants and metal deactivators have the opposite effect. For the particular systems studied durability is decreased in samples containing the lubricant and UV stabilizers and increased in samples stabilized with the antioxidant and metal deactivator.
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  • 12
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    Journal of inorganic and organometallic polymers and materials 2 (1992), S. 79-85 
    ISSN: 1572-8870
    Keywords: Phthalocyanines ; polymers ; siloxanes ; conductivity ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The author's work on the incorporation of phthalocyanines into inorganic polymers is reviewed. The synthesis of poly(siloxane phthalocyanines) and the synthesis and characterization of fluoro(phthalocyanine) Group III compounds and their conducting derivatives are described.
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  • 13
    ISSN: 1572-8927
    Keywords: Chromium(III) ; β-diketones ; β-diketonates ; chelation ; complexation ; correlation ; stability ; equilibrium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract It has been demonstrated that the logarithm of the stability constant of some monochelated chromium(III) compounds, with structurally similar 1,3-dicarbonylic species, is linearly related to the negative logarithm of the acid ionization constant of the ligand. Graphical and analytical correlations which could be useful in predicting equilibrium constants of chromium(III)-β-diketonates, as well as other first-row transition metal derivatives, have been developed. A quantitative evaluation of the complexes stability has been carried out, providing information about the effects of ligand substituents on the equilibrium constants.
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  • 14
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    Catalysis letters 10 (1991), S. 225-232 
    ISSN: 1572-879X
    Keywords: VPI-5 ; stability ; molecular sieve ; post-synthesis treatments
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Thorough washing of a VPI-5 synthesized with n-dipropylamine as template improves greatly its thermal stability while no major change is observed in the template content. A detailed study of the influence of the pretreatment conditions shows that in order to obtain a high thermal stability (up to at least 960 °C) two parameters are of importance. The removal of both the template and the adsorbed water requires either a low heating rate at atmospheric pressure or a low pressure (less than 3 Torr) when the heating rate is 300 ° per hour.
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  • 15
    ISSN: 1572-8773
    Keywords: catalase ; copper resistance ; pH-dependent growth ; Saccharomyces cerevisiae ; superoxide dismutase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract A strain of Saccharomyces cerevisiae has been adapted to increasing concentrations of copper at two different pH values. The growth curve at pH 5.5 is characterized by a time generation increasing with the amount of added copper. A significant decrease of cell volume as compared with the control is also observed. At pH 3 the cells grow faster than at pH 5.5 and resist higher copper concentrations (3.8 against 1.2 mm). Experimental evidence indicates that, after copper treatment, the metal is not bound to the cell wall, but is localized intracellularly. A significant precipitation of copper salts in the medium was observed only at pH 5.5. Increased levels of superoxide dismutase (SOD) activity were observed in copper-treated cells and which persisted after 20 subsequent inocula in a medium without added metal. On the contrary, catalase activity was not stimulated by copper treatment and, hence, not correlated with SOD levels. The mechanism of copper resistance, therefore, probably involves a persistent induction of SOD, but not of catalase, and it is strongly pH-dependent.
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  • 16
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    Journal of dynamics and differential equations 6 (1994), S. 37-51 
    ISSN: 1572-9222
    Keywords: Celestial mechanics ; relative equilibria ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract A criterion for the linear stability of relative equilibria of the Newtoniann-body problem is found in the case whenn−1 of the masses are small. Several stable periodic orbits of the problem are presented as examples.
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  • 17
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    Order 9 (1992), S. 163-175 
    ISSN: 1572-9273
    Keywords: Primary 06A07 ; secondary 05C70 ; Partial order ; interval ; stability ; covering ; Sperner property ; symmetric chains ; NP-completeness
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Given a finite ranked posetP, let α(P) be the maximum size of a subset ofP such that no two elements of it belong simultaneously to some interval ofP and let ϱ(P) be the minimum number of intervals covering all elements ofP. We say thatP has the strong interval stability property (resp. the strong interval covering property) if for each subposetP′ induced by consecutive levels ofP, i.e.,P′=P (l)∪...∪P (u), one has α(P′)=max{|P (l)|, |P (u)|} (resp. ϱ(P′)=max{|P (l)|, |P (u)|}). We prove these properties for several classes of posets and discuss some general facts concerning the numbers α(P) and ϱ(P), e.g., NP-completeness and min-max relations.
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  • 18
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    Queueing systems 12 (1992), S. 369-389 
    ISSN: 1572-9443
    Keywords: Perturbation analysis ; stability ; stochastic difference equations ; simulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract We investigate the stability of waiting-time derivatives when inputs to a queueing system-service times and interarrival times-depend on a parameter. We give conditions under which the sequence of waiting-time derivatives admits a stationary distribution, and under which the derivatives converge to the stationary regime from all initial conditions. Further hypotheses ensure that the expectation of a stationary waiting-time derivative is, in fact, the derivative of the expected stationary waiting time. This validates the use of simulation-based infinitesimal perturbation analysis estimates with a variety of queueing processes. We examine waiting-time sequences satisfying recursive equations. Our basic assumption is that the input and its derivatives are stationary and ergodic. Under monotonicity conditions, the method of Loynes establishes the convergence of the derivatives. Even without such conditions, the derivatives obey a linear difference equation with random coefficients, and we exploit this fact to find stability conditions.
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  • 19
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    Queueing systems 13 (1993), S. 87-110 
    ISSN: 1572-9443
    Keywords: Manufacturing systems ; semiconductor manufacturing ; thin film lines ; re-entrant lines ; scheduling policies ; queueing networks ; buffer priority policies ; due date policies ; stability ; stochastic control ; mean delay ; variance of delay ; machine failures ; set-up times
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Traditionally, manufacturing systems have mainly been treated as either job shops or flow shops. In job shops, parts may arrive with random routes, with each route having a low volume. In flow shops, the routes are fixed and acyclic, as in assembly lines. With the advent of semiconductor manufacturing plants, and more recently, thin film lines, this dichotomy needs to be expanded to consider another class of systems, which we call “re-entrant lines”. The distinguishing feature of these manufacturing systems is that parts visit some machines more than once at different stages of processing. Scheduling problems arise because several parts at different stages of processing may be in contention with each other for service at the same machine. There may be uncertainties in the form of random service or set-up times, as well as random machine failures and repairs. The goal of scheduling is to improve performance measures such as mean sojourn time in the system, which is also known as the mean “cycle-time”, or the variance of the cycle-time. In this paper we provide a tutorial account of some recent results in this field. We describe several scheduling policies of interest, and provide some results concerning their stability and performance. Several open problems are suggested.
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  • 20
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    Queueing systems 15 (1994), S. 279-288 
    ISSN: 1572-9443
    Keywords: Sample-path ; point processes ; workload ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract In this paper, by exploiting recent results on the pathwise behavior of the workload process in single server, work conserving queues of theG/G/1/∞ type, we show that the workload of multiserver, work conserving queues ofG/G/m/∞ (m〈∞) (andG/G/∞) queues satisfies an o(t) growth condition, provided that the time average of the work brought into the system is less thanm form 〈 ∞ (and finite form=∞).
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  • 21
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    Queueing systems 16 (1994), S. 115-137 
    ISSN: 1572-9443
    Keywords: Polling systems ; stability ; stochastic continuity ; general arrival process ; functional limit theorems.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract The stability of a polling system with exhaustive service and a finite number of users, each with infinite buffers is considered. The arrival process is more general than a Poisson process and the system is not slotted. Stochastic continuity of the stationary distributions, rates of convergence and functional limit theorems for the queue length and waiting time processes have also been proved. The results extend to the gated service discipline.
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  • 22
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    Celestial mechanics and dynamical astronomy 56 (1993), S. 45-50 
    ISSN: 1572-9478
    Keywords: Restricted problem ; stability ; planets of double stars
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Numerical simulations are made within the framework of the plane restricted three-body problem, in order to find out if stable orbits for planets around one of the two components in double stars can exist. For any given set of initial parameters (the mass ratio of the two stars and the eccentricity of their orbit around each other), the phase-space of initial positions and velocities is systematically explored. In previous works, systematic exploration of the circular model as well as studies of more realistic (elliptic) cases such as Sun-Jupiter and the nearby α Centauri and Sirius systems, large stable planetary orbits were found to exist around both components of the binary, up to distances from each star of the order or more than half the binary's periastron separation. The first results presented here for the η Coronae Borealis system confirm the previous studies.
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  • 23
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    Celestial mechanics and dynamical astronomy 58 (1994), S. 203-213 
    ISSN: 1572-9478
    Keywords: libration points ; resonances ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The stability of the triangular libration points in the case when the first and the second order resonances appear was investigated. It was proved that the first order resonances do not cause instability. The second order resonances may lead to instability. Domains of the instability in the two-dimensional parameter space were determined.
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  • 24
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    Journal of dynamics and differential equations 5 (1993), S. 625-671 
    ISSN: 1572-9222
    Keywords: Scalar reaction-diffusion equation ; singular perturbation methods ; internal layer ; Neumann layer ; stability ; 35K57 ; 35B25 ; 35B35
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract The multiple existences and their stability properties of stationary solutions with a single transition layer in some scalar reaction-diffusion equation are shown. Each solution is constructed by using classical singular perturbation methods and its stability property is determined by a simple algebraic quantity, say index, appearing in the construction of a solution.
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  • 25
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    Journal of dynamics and differential equations 6 (1994), S. 639-658 
    ISSN: 1572-9222
    Keywords: Symmetry ; parabolic equations ; positive solutions ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Symmetry properties of positive solutions of a Dirichlet problem for a strongly nonlinear parabolic partial differential equation in a symmetric domainD ⊂ R n are considered. It is assumed that the domainD and the equation are invariant with respect to a group {Q} of transformations ofD. In examples {Q} consists of reflections or rotations. The main result of the paper is the theorem which states that any compact inC(D) negatively invariant set which consists of positive functions consists ofQ-symmetric functions. Examples of negatively invariant sets are (in autonomous case) equilibrium points, omega-limit sets, alpha-limit sets, unstable sets of invariant sets, and global attractors. Application of the main theorem to equilibrium points gives the Gidas-Ni-Nirenberg theorem. Applying the theorem to omega-limit sets, we obtain the asymptotical symmetrization property. That means that a bounded solutionu(t) asr→∞ approaches subspace of symmetric functions. One more result concerns properties of eigenfunctions of linearizations of the equations at positive equilibrium points. It is proved that all unstable eigenfunctions are symmetric.
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  • 26
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    Annals of operations research 27 (1990), S. 343-369 
    ISSN: 1572-9338
    Keywords: Bifurcation ; singularities ; continuation ; parametric nonlinear programming ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Notes: Abstract Bifurcation and continuation techniques are introduced as a class of methods for investigating the parametric nonlinear programming problem. Motivated by the Fritz John first-order necessary conditions, the parametric programming problem is first reformulated as a closed system of nonlinear equations which contains all Karush-Kuhn-Tucker and Fritz John points, both feasible and infeasible solutions, and relative minima, maxima, and saddle points. Since changes in the structure of the solution set and critical point type can occur only at singularities, necessary and sufficient conditions for the existence of a singularity are developed in terms of the loss of a complementarity condition, the linear dependence constraint qualification, and the singularity of the Hessian of the Lagrangian on a tangent space. After a brief introduction to elementary bifurcation theory, some simple singularities in this parametric problem are analyzed for both branching and persistence of local minima. Finally, a brief introduction to numerical continuation and bifurcation procedures is given to indicate how these facts can be used in a numerical investigation of the problem.
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  • 27
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    Queueing systems 14 (1993), S. 159-175 
    ISSN: 1572-9443
    Keywords: Queueing networks ; nonproduct form networks ; stability ; stochastic continuity ; functional limit theorems
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract A finite number of nodes, each with a single server and infinite buffers, is considered in discrete time. The service may be FIFO and the service times are constant. The external arrivals and the routing decision variables form a general stationary sequence. Stability of the system is proved under these assumptions. Extension to multiple servers at a node and general stationary distributions holds. If the external input is i.i.d. and the routing is Markovian then stochastic ordering, continuity of stationary distributions, rates of convergence, a functional CLT and a functional LIL and various other limit theorems for the queue length process are also proved. Generalizations to multiple servers at nodes, customers with priority, multiple customer classes, general service length and Markov modulated external arrival cases are discussed.
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    Queueing systems 15 (1994), S. 211-238 
    ISSN: 1572-9443
    Keywords: polling system ; stability ; Markov chain ; stochastic monotonicity ; heavy traffic ; nonpreemptive local priority
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    Topics: Computer Science
    Notes: Abstract This paper deals with the stability of periodic polling models with a mixture of service policies. Customers arrive according to independent Poisson processes. The service times and the switchover times are independent with general distributions. The necessary and sufficient condition for the stability of such polling systems is established. The proof is based on the stochastic monotonicity of the state process at the polling instants. The stability of only a subset of the queues is also analyzed and, in case of heavy traffic, the order of explosion of the queues is given. The results are valid for a model with set-up times, and also when there is a local priority rule at the queues.
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    Queueing systems 17 (1994), S. 317-345 
    ISSN: 1572-9443
    Keywords: Single-server queue ; spatially distributed arrival points ; travelling server ; Brownian motion ; embedded Markov chain ; stability ; Tweedie's lemma ; regenerative processes ; stochastic decomposition ; equilibrium equations ; mean queue length
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    Topics: Computer Science
    Notes: Abstract Consider a queueing system where customers arrive at a circle according to a homogeneous Poisson process. After choosing their positions on the circle, according to a uniform distribution, they wait for a single server who travels on the circle. The server's movement is modelled by a Brownian motion with drift. Whenever the server encounters a customer, he stops and serves this customer. The service times are independent, but arbitrarily distributed. The model generalizes the continuous cyclic polling system (the diffusion coefficient of the Brownian motion is zero in this case) and can be interpreted as a continuous version of a Markov polling system. Using Tweedie's lemma for positive recurrence of Markov chains with general state space, we show that the system is stable if and only if the traffic intensity is less than one. Moreover, we derive a stochastic decomposition result which leads to equilibrium equations for the stationary configuration of customers on the circle. Steady-state performance characteristics are determined, in particular the expected number of customers in the system as seen by a travelling server and at an arbitrary point in time.
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    Queueing systems 11 (1992), S. 7-33 
    ISSN: 1572-9443
    Keywords: Token passing rings ; stability ; substability ; ergodicity ; Markov chains ; Loynes' scheme ; stochastically dominant ; Little's formula ; regenerative processes
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    Topics: Computer Science
    Notes: Abstract A sufficient stability condition for the standard token passing ring has been “known” since the seminal paper by Kuehn in 1979. However, this condition was derived without formal proof, and the proof seems to be of considerable interest to the research community. In fact, Watson observed that in the performance evaluation of token passing rings, “it is convenient to derive stability conditions ... (without proof)”. Our intention is to fill this gap, and to provide a formal proof of thesufficient and necessary stability condition for the token passing ring. In this paper, we present the case when the arrival process to each queue is Poisson but service times and switchover times are generally distributed. We consider in depth a gatedl-limited (l≤ ∞) service discipline for each station. We also indicate that the basic steps of our technique can be used to study the stability of some other multiqueue systems.
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    Celestial mechanics and dynamical astronomy 59 (1994), S. 345-374 
    ISSN: 1572-9478
    Keywords: Lagrangian points ; stability ; oblate primary
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    Topics: Physics
    Notes: Abstract The non-linear stability of the libration pointL 4 in the restricted problem has been studied when there are perturbations in the potentials between the bodies. It is seen that the pointL 4 is stable for all mass ratios in the range of linear stability except for three mass ratios depending upon the perturbing functions. The theory is applied to the following four cases: (i) There are no perturbations in the potentials (classical problem). (ii) Only the bigger primary is an oblate spheroid whose axis of symmetry is perpendicular to the plane of relative motion (circular) of the primaries. (iii) Both the primaries are oblate spheroids whose axes of symmetry are perpendicular to the plane of relative motion (circular) of the primaries. (iv) The primaries are spherical in shape and the bigger is a source of radiation.
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    Journal of dynamics and differential equations 5 (1993), S. 189-218 
    ISSN: 1572-9222
    Keywords: Equivariant bifurcation ; symmetry ; singularity ; equivariant jets and transversality ; normal forms ; universal unfolding ; stability ; structural stability ; 58F14 ; 58E07 ; 58C27
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract The theoretical machinery from singularity theory introduced by Golubitsky, Stewart, and Schaeffer, to study equivariant bifurcation problems, is completed and expanded while generalized to the multiple parameter context. In this setting the finite determinacy theorems or normal forms, the stability of equivariant bifurcation problems, and the structural stability of the universal unfolding are discussed.
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    Journal of dynamics and differential equations 6 (1994), S. 447-486 
    ISSN: 1572-9222
    Keywords: Free boundary problems ; gasless combustion ; stability ; Hopf bifurcation ; 35R35 ; 35B40 ; 80A25
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    Topics: Mathematics
    Notes: Abstract In this paper, we analyze a simple free boundary model associated with solid combustion and some phase transition processes. There is strong evidence that this “one-phase” model captures all major features of dynamical behavior of more realistic (and complicated) combustion and phase transition models. The principal results concern the dynamical behavior of the model as a bifurcation parameter (which is related to the activation energy in the case of combustion) varies. We prove that the basic uniform front propagation is asymptotically stable against perturbations for the bifurcation parameter above the instability threshold and that a Hopf bifurcation takes place at the threshold value. Results of numerical simulations are presented which confirm that both supercritical and subcritical Hofp bifurcation may occur for physically reasonable nonlinear kinetic functions.
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    Set-valued analysis 1 (1993), S. 393-402 
    ISSN: 1572-932X
    Keywords: Primary: 49J40, 65K10, 47A55, 47H05, 65L20 ; Variational inequality ; perturbation ; unbounded and nonsmooth operators ; convex sets ; Hausdorff distance ; regularization ; monotonicity ; convergence ; stability
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    Topics: Mathematics
    Notes: Abstract The stability and convergence of the solutions of perturbed and regularized variational inequality to the solutions of the primary (unstable a priori) variational inequality with proper monotone operator are investigated. All the objects of inequality: the operatorA, the right-hand partf and the set of constrains Ω are to be perturbed. At the same time no assumptions of boundedness and smoothness of the operatorA are used. The connection between the parameters of perturbations, which guarantees strong convergence of approximate solutions, is established. It is proved that the existence of the solution to the unperturbed variational inequality is necessary and sufficient condition for convergence of the regularized perturbed inequality solutions.
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    Queueing systems 6 (1990), S. 335-351 
    ISSN: 1572-9443
    Keywords: State-dependent service and interarrival times ; Lindley equation ; recursive stochastic equations ; stability ; stochastic comparisons ; normal approximations ; scheduling arrivals
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    Topics: Computer Science
    Notes: Abstract We consider a modification of the standardG/G/1 queue with unlimited waiting space and the first-in first-out discipline in which the service times and interarrival times depend linearly and randomly on the waiting times. In this model the waiting times satisfy a modified version of the classical Lindley recursion. We determine when the waiting-time distributions converge to a proper limit and we develop approximations for this steady-state limit, primarily by applying previous results of Vervaat [21] and Brandt [4] for the unrestricted recursionY n+1=C n Y n +X n . Particularly appealing for applications is a normal approximation for the stationary waiting time distribution in the case when the queue only rarely becomes empty. We also consider the problem of scheduling successive interarrival times at arrival epochs, with the objective of achieving nearly maximal throughput with nearly bounded waiting times, while making the interarrival time sequence relatively smooth. We identify policies depending linearly and deterministically upon the work in the system which meet these objectives reasonably well; with these policies the waiting times are approximately contained in a specified interval a specified fraction of time.
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    Journal of dynamics and differential equations 4 (1992), S. 161-190 
    ISSN: 1572-9222
    Keywords: Delay differential equations ; equilibrium ; stability ; limiting equations ; population dynamics ; 34K20 ; 34K25 ; 92A15
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    Topics: Mathematics
    Notes: Abstract Applying an analytical method and several limiting equations arguments, some sufficient conditions are provided for the existence of a unique positive equilibriumK for the delay differential equationx=−γx+D(x t ), which is the general form of many population models. The results are concerned with the global attractivity, uniform stability, and uniform asymptotic stability ofK. Application of the results to some known population models, which shows the effectiveness of the methods applied here, is also presented.
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    Journal of dynamics and differential equations 5 (1993), S. 105-128 
    ISSN: 1572-9222
    Keywords: Delay system ; stability ; relative variance ; dynamical disease
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    Topics: Mathematics
    Notes: Abstract A new approach to the study of delay systems, applicable to physiological control systems and other systems where little information about the time delays is available, is examined. The method is based on the fact that stability information can be deduced from the statistical properties of the probability distribution that encodes the structure of the time delay. The main statistical variables used are the usual expectation parameter,E, and a modified variance, calledrelative variance and denotedR, that is invariant under time scale changes. Recent work of the author has shown that stability often improves asR increases whileE remains fixed. A four-parameter family of delay models is analysed in this paper, and the (E, R) pair is found to be a reliable indicator of stability over the global parameter domain of the family.
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    Journal of dynamics and differential equations 6 (1994), S. 325-334 
    ISSN: 1572-9222
    Keywords: Nonlinear Schrödinger equations ; anisotropic standing waves ; stability ; concentration compactness principle ; Davey-Stewartson system ; 35Q35 ; 35B35
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    Topics: Mathematics
    Notes: Abstract We study the stability of standing waves for a nonlinear Schrödinger equation, which derives from the generalized Davey-Stewartson system in the elliptic-elliptic case. We prove the existence of stable standing waves under certain conditions.
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    Journal of dynamics and differential equations 6 (1994), S. 631-637 
    ISSN: 1572-9222
    Keywords: stability ; fixed point index ; periodic solutions
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    Topics: Mathematics
    Notes: Abstract In this paper, we prove that a stable isolated fixed point of an orientation preserving local homeomorphism onR 2 has fixed point index 1. We also give a number of applications to differential equations. In particular, we deduce that a number of existence methods for producing periodic solutions of differential equations in the plane always produce unstable solutions.
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    Journal of solution chemistry 22 (1993), S. 1151-1158 
    ISSN: 1572-8927
    Keywords: Molecular complexes ; solvent effect ; stability ; solid CT complexes ; nicotine
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    Topics: Chemistry and Pharmacology
    Notes: Abstract Interaction of nicotine with tetracyanoethylene and iodine was investigated spectrophotometrically and found to form strong CT complexes (n−π and n-σ*, respectively). The donor site involved in CT interaction is the pyrrolidine nitrogen. The nicotine-I2 complex exists as the ionic structure (nicotine) I+-I 3 − . Formation constants of the CT complexes in various solvents were determined from 10 to 25°C and are discussed in terms of the nature of the electron acceptor and solvent polarity. Solid CT complexes were synthesized and were characterized by microchemical analysis and infrared spectra techniques.
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    Acta applicandae mathematicae 28 (1992), S. 1-42 
    ISSN: 1572-9036
    Keywords: 35R30 ; Inverse scattering ; stability ; noisy data
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    Topics: Mathematics
    Notes: Abstract An algorithm is given for calculating the solution to the 3D inverse scattering problem with noisy discrete fixed energy data. The error estimates for the calculated solution are derived. The methods developed are of a general nature and can be used in many applications: in nondestructive evaluation and remote sensing, in geophysical exploration, medical diagnostics, and technology.
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    Annals of global analysis and geometry 11 (1993), S. 387-395 
    ISSN: 1572-9060
    Keywords: Curvatures of hypersurfaces ; Reilly's inequality ; stability ; 53 A 10 ; 53 C 42
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    Topics: Mathematics
    Notes: Abstract We generalize Reilly's inequality for the first eigenvalue of immersed submanifolds ofIR m +1 and the total (squared) mean curvature, to hypersurfaces ofIR m +1 and the first eigenvalue of the higher order curvatures. We apply this to stability problems. We also consider hypersurfaces in hyperbolic space.
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    BIT 33 (1993), S. 332-350 
    ISSN: 1572-9125
    Keywords: AMS(MOS): 65L06 ; Multistep collocation method ; continuous solution ; stability
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    Topics: Mathematics
    Notes: Abstract This paper describes an implementation of multistep collocation methods, which are applicable to stiff differential problems, singular perturbation problems, and D.A.E.s of index 1 and 2. These methods generalize one-step implicit Runge-Kutta methods as well as multistep one-stage BDF methods. We give numerical comparisons of our code with two representative codes for these methods, RADAU5 and LSODE.
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    Annals of global analysis and geometry 11 (1993), S. 221-235 
    ISSN: 1572-9060
    Keywords: Second variation formula ; Morse index ; stability ; 53C
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    Topics: Mathematics
    Notes: Abstract Iff is a minimal, isometric immersion of the Riemannian manifoldM of dimensionn in a Riemannian manifold $$\overline M$$ of dimensionm and ifI N is the „differential Jacobi operator” acting on the cross sections of the normal bundleN(M), we obtain some information on the Morse index and on the stability ofM through a detailed geometric analysis of the immersionf obtained when considering the higher fundamental forms off.
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    BIT 30 (1990), S. 332-346 
    ISSN: 1572-9125
    Keywords: 65D05 ; polynomial interpolaton ; Newton form ; stability ; Leja points ; ordering of interpolation points
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    Topics: Mathematics
    Notes: Abstract The Newton form is a convenient representation for interpolation polynomials. Its sensitivity to perturbations depends on the distribution and ordering of the interpolation points. The present paper bounds the growth of the condition number of the Newton form when the interpolation points are Leja points for fairly general compact sets K in the complex plane. Because the Leja points are defined recursively, they are attractive to use with the Newton form. If K is an interval, then the Leja points are distributed roughly like Chebyshev points. Our investigation of the Newton form defined by interpolation at Leja points suggests an ordering scheme for arbitrary interpolation points.
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    BIT 32 (1992), S. 634-649 
    ISSN: 1572-9125
    Keywords: AMS(MOS): 65L20 ; CR: 5.17 ; delay differential equations ; numerical solution ; Runge-Kutta methods ; interpolation procedures ; stability
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    Topics: Mathematics
    Notes: Abstract This paper deals with adapting Runge-Kutta methods to differential equations with a lagging argument. A new interpolation procedure is introduced which leads to numerical processes that satisfy an important asymptotic stability condition related to the class of testproblemsU′(t)=λU(t)+μU(t−τ) with λ, μ ε C, Re(λ)〈−|μ|, and τ〉0. Ifc i denotes theith abscissa of a given Runge-Kutta method, then in thenth stept n−1→t n :=t n−1+h of the numerical process our interpolation procedure computes an approximation toU(t n−1+c i h−τ) from approximations that have already been generated by the process at pointst j−1+c i h(j=1,2,3,...). For two of these new processes and a standard process we shall consider the convergence behaviour in an actual application to a given, stiff problem.
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    Celestial mechanics and dynamical astronomy 49 (1990), S. 219-231 
    ISSN: 1572-9478
    Keywords: n-body problem ; stability ; relative equilibrium
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    Topics: Physics
    Description / Table of Contents: Abstract We prove in this paper the instability, for all n ⩾ 4, of the configurations of relative equilibrium in the n-body problem where the n bodies submitted to newtonian mutual attractions are at the vertices of a regular polypon with n sides. For this proof we show that the equations of variations projected to the n bodies plan P have at least two conjugate characteristic exponents with a strictly positive real part; while these equations projected to an orthogonal axis to P have some solutions with secular terms.
    Notes: Resumé On démontre dans cet article l'instabilité, pour tout n ⩾ 4, des configurations d'équilibre relatif dans le problème des n corps, oú les n corps soumises aux attractions newtonniennes mutuelles se trouvent aux sommets d'un polygone régulier de n cotés. La preuve consiste à montrer que les équations aux variations, projetées sur le plan P des n corps, possèdent au moins deux exposants caractéristiques complexes connugués dont la parr'e réelle est strictement positive; alors que ces equations projetées sur un axe orthogonal à P possèdent des solutions ayant des termes séculaires.
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    Celestial mechanics and dynamical astronomy 53 (1992), S. 145-150 
    ISSN: 1572-9478
    Keywords: Monodromy matrix ; Gauss hypergeometric equation ; stability
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    Notes: Abstract A new class of linear ordinary differential equations with periodic coefficients is found which can be transformed to the Gauss hypergeometric equation, and therefore the monodromy matrices are computable explicitly. These equations appear as the variational equations around a straight-line solution in Hamiltonian systems of the form H = T(p) + V(q), where T(p) and V(q) are homogeneous functions of p and q, respectively.
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    Celestial mechanics and dynamical astronomy 56 (1993), S. 323-324 
    ISSN: 1572-9478
    Keywords: chaos ; stability ; asteroids
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    Celestial mechanics and dynamical astronomy 57 (1993), S. 59-94 
    ISSN: 1572-9478
    Keywords: asteroids ; libration ; proper elements ; stability ; chaos ; families
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    Topics: Physics
    Notes: Abstract I have computed proper elements for 174 asteroids in the 1 : 1 resonance with Jupiter, that is for all the reliable orbits available (numbered and multi-opposition). The procedure requires numerical integration, under the perturbations by the four major planets, for 1,000,000 years; the output is digitally filtered and compressed into a “synthetic theory” (as defined within theLONGSTOP project). The proper modes of oscillation of the variables related to eccentricity, perihelion, inclination and node define proper elements. A third proper element is defined as the amplitude of the oscillation of the semimajor axis associated with the libration period; because of the strong nonlinearity of the problem, this component cannot be determined by a simple Fourier transform to the frequency domain. I therefore give another definition, which results in very good stability with time. For 87% of the computed orbits, the stability of the proper elements-at least over 1M yr-is within the following bounds: 0.001AU in semimajor axis, 0.0025 in eccentricity and sine of inclination. Half of the cases with degraded stability of the proper elements are found to be chaotic, with e-folding times between 16,000 and 660,000yr; in some other cases, chaotic behaviour does not result in a significantly decreased stability of the proper elements (stable chaos). The accuracy and stability of these proper elements is good enough to allow a search for asteroid families; however, the dynamical structure of the Trojan belt is very different from the one of the main belt, and collisional events among Trojans can result in a distribution of fragments difficult to identify. The occurrence of couples of Trojans with very close proper elements is proven not to be statistically significant in almost all cases. As the only exception, the couple 1583 Antilochus — 3801 Thrasimedes is significant; however, it is not easy to account for it by a conventional collisional theory. The Menelaus group is confirmed as a strong candidate collisional family; Teucer and Sarpedon could be considered as significant clusters. A number of other clumps are detected (by the same automated clustering method used for the main belt by Zappalà et al., 1990, 1992), but the total number of Trojans with reliable orbits is not large enough to detect many significant candidate families.
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    Celestial mechanics and dynamical astronomy 49 (1990), S. 249-264 
    ISSN: 1572-9478
    Keywords: Solar sails ; radiation pressure ; stability
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    Topics: Physics
    Notes: Abstract The form of the solar radiation pressure on a heliocentric orbiting solar sail is obtained for a finite angular sized and limb darkened solar disk by the use of the radiation pressure tensor. It is found that the usual inverse square variation of the solar radiation pressure is modified by the finite angular size, and to a lesser extent by the solar limb darkening. The actual magnitude of the modification is in itself small, except at close heliocentric distances. However, its existence has implications for the dynamical stability of solar sails both in parked and circular orbital configurations and for the accuracy of trajectory calculations, particularly for sails in the inner solar system.
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    Celestial mechanics and dynamical astronomy 60 (1994), S. 307-315 
    ISSN: 1572-9478
    Keywords: Asteroid ; libration ; resonance ; stability
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    Topics: Physics
    Notes: Abstract It is known that an abridged case of the averaged planar general three-body problem, at first-order resonance, is analytically integrated, using an expansion of the disturbing function linear in the eccentricities. There exist different methods with the help of which the integration can be performed. For the first time Sessin and Ferraz-Mello in the years 1981–88 (Sessin, 1981, 1983; Ferraz-Mello and Sessin, 1984; Ferraz-Mello, 1987, 1988) did an analytic integration for the restricted elliptic three-body problem, in terms of the variablesK andH (K=ΣD j e j cos (ψ1−π j ),H=ΣD j e j sin (ψ1−π j ),D j = const, wheree j and π j are, respectively, the eccentricity and the longitude of the periapsis of thei-th planet, ψ1 is the Delaunay's anomaly), which is inconvenient for the analytical investigation of the evolution of the major semi-axesa j , the eccentricitiese j and the resonance phases ϕ j =ψ1−π j . Later, a different method for the analytical integration of the general three-body problem, in the variablesa j ,e j and ϕ j , was considered by the author (Shinkin, 1993). A disadvantage of both methods is the fact that they use non-canonical changes of variables. But there exists a third very beautiful canonical method of analytical integration of the general planetary problem, which is briefly considered in the present paper and allows us to describe the bifurcations of separatrices (i.e. appearance, disappearance, splitting and confluence of separatrices) separating the domains of libration and circulation of the resonance phase on the phase plane in the averaged planar general three-body problem at first-order resonance. The bifurcation parameter is analytically found and plays an important role in a qualitative description of all kinds of motion in the examined problem.
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    Acta applicandae mathematicae 37 (1994), S. 129-136 
    ISSN: 1572-9036
    Keywords: 35B35 ; 35Q30 ; 76N10 ; stability ; Navier-Stokes equations ; compressible fluids
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    Topics: Mathematics
    Notes: Abstract We prove that the uniform stability at permanently acting disturbances of a given solution of the Navier-Stokes equations for viscous compressible isothermic fluid is a consequence of the uniform exponential stability of the zero solution of so-called linearized equations.
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    Celestial mechanics and dynamical astronomy 53 (1992), S. 219-226 
    ISSN: 1572-9478
    Keywords: Artificial satellite ; dissipative forces ; stability
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    Notes: Abstract The effects of small external dissipative and disturbing forces on the non-linear planar oscillation of a cable connected satellites system in the central gravitational field of earth have been studied. Typical non-linear oscillation's phenomena arizing from the aforesaid external forces are shown to take place. The presence of these forces enables the application of asymptotic methods of the theory of non-linear oscillations due to Bogoliubov and Mitropolsky to the equation characterizing the non-linear oscillation of the system.
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    Celestial mechanics and dynamical astronomy 60 (1994), S. 249-271 
    ISSN: 1572-9478
    Keywords: Chaos ; periodic orbits ; stability ; asymptotic curves ; homoclinic points ; heteroclinic points
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    Topics: Physics
    Notes: Abstract We study the structure of chaos in a simple Hamiltonian system that does no have an escape energy. This system has 5 main periodic orbits that are represented on the surface of section $$(y,\dot y)$$ by the points (1)O(0,0), (2)C 1,C 2(±y c, 0), (3)B 1,B 2(O,±1) and (4) the boundary $$y^2 + \dot y^2 = 1$$ . The periodic orbits (1) and (4) have infinite transitions from stability (S) to instability (U) and vice-versa; the transition values of ε are given by simple approximate formulae. At every transitionS →U a set of 4 asymptotic curves is formed atO. For larger ε the size and the oscillations of these curves grow until they destroy the closed invariant curves that surroundO, and they intersect the asymptotic curves of the orbitsC 1,C 2 at infinite heteroclinic points. At every transitionU →S these asymptotic curves are duplicated and they start at two unstable invariant points bifurcating fromO. At the transition itself the asymptotic curves fromO are tangent to each other. The areas of the lobes fromO increase with ε; these lobes increase even afterO becomes stable again. The asymptotic curves of the unstable periodic orbits follow certain rules. Whenever there are heteroclinic points the asymptotic curves of one unstable orbit approach the asymptotic curves of another unstable orbit in a definite way. Finally we study the tangencies and the spirals formed by the asymptotic curves of the orbitsB 1,B 2. We find indications that the number of spiral rotations tends to infinity as ε → ∞. Therefore new tangencies between the asymptotic curves appear for arbitrarily large ε. As a consequence there are infinite new families of stable periodic orbits that appear for arbitrarily large ε.
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    Celestial mechanics and dynamical astronomy 55 (1993), S. 249-259 
    ISSN: 1572-9478
    Keywords: Asteroid ; libration ; resonance ; stability
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    Notes: Abstract This paper investigates the stability of the motion in the averaged planar general three-body problem in the case of first-order resonance. The equations of the averaged motion of bodies near the resonance surface is obtained and is analytically integrated by quadratures. The stability of the averaged motion is analytically investigated in relation to the semi-major axes, the eccentricities and the resonance phases. An autonomous second-order equation is obtained for the deviation of semiaxes from the resonance surface. This equation has an energy integral and is analytically integrated by quadratures. The quasi-periodic dependence on time with two-frequency basis of the averaged motion of bodies is found. The basic frequencies are analytically calculated. With the help of the mean functionals calculated along integral curves of the averaged problem the new analytic first integrals are constructed with coefficients periodic in time. The analytic conditions of librations of resonance phases are obtained.
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    Celestial mechanics and dynamical astronomy 55 (1993), S. 323-330 
    ISSN: 1572-9478
    Keywords: Periodic orbits ; rigid body dynamics ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The equations of motion of a rigid body about a fixed point in a central Newtonian field is reduced to the equation of plane motion under the action of potential and gyroscopic forces, using the isothermal coordinates on the inertia ellipsoid. The construction of periodic solutions near the equilibrium points, by using the Lipaunov theorem of holomorphic integral, is obtained and the necessary and sufficient conditions for the stability of the system are given.
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  • 58
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    Celestial mechanics and dynamical astronomy 55 (1993), S. 351-367 
    ISSN: 1572-9478
    Keywords: Sitnikov's problem ; invariant rotational curves ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The Sitnikov's Problem is a Restricted Three-Body Problem of Celestial Mechanics depending on a parameter, the eccentricity,e. The Hamiltonian,H(z, v, t, e), does not depend ont ife=0 and we have an integrable system; ife is small the KAM Theory proves the existence of invariant rotational curves, IRC. For larger eccentricities, we show that there exist two complementary sequences of intervals of values ofe that accumulate to the maximum admissible value of the eccentricity, 1, and such that, for one of the sequences IRC around a fixed point persist. Moreover, they shrink to the planez=0 ase tends to 1.
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  • 59
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    Celestial mechanics and dynamical astronomy 60 (1994), S. 99-129 
    ISSN: 1572-9478
    Keywords: Sitnikov motions ; periodic orbits ; stability ; bifurcations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In this paper we deal with the circular Sitnikov problem as a subsystem of the three-dimensional circular restricted three-body problem. It has a first analytical part where by using elliptic functions we give the analytical expressions for the solutions of the circular Sitnikov problem and for the period function of its family of periodic orbits. We also analyze the qualitative and quantitative behavior of the period function. In the second numerical part, we study the linear stability of the family of periodic orbits of the Sitnikov problem, and of the families of periodic orbits of the three-dimensional circular restricted three-body problem which bifurcate from them; and we follow these bifurcated families until they end in families of periodic orbits of the planar circular restricted three-body problem. We compare our results with the previous ones of other authors on this problem. Finally, the characteristic curves of some bifurcated families obtained for the mass parameter close to 1/2 are also described.
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  • 60
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    BIT 33 (1993), S. 74-84 
    ISSN: 1572-9125
    Keywords: 65J10 ; 65M12 ; Analytic semigroup ; Banach space ; rational approximation ; A-acceptable ; A(θ)-acceptable ; stability ; Crank-Nicolson method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract It is shown thatA-acceptable and, more generally,A(θ)-arational approximations of bounded analytic semigroups in Banach space are stable. The result applies, in particular, to the Crank-Nicolson method.
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  • 61
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    BIT 33 (1993), S. 285-303 
    ISSN: 1572-9125
    Keywords: 65L05 ; stiffness ; stability ; pseudospectra
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract It is argued that even for a linear system of ODEs with constant coefficients, stiffness cannot properly be characterized in terms of the eigenvalues of the Jacobian, because stiffness is a transient phenomenon whereas the significance of eigenvalues is asymptotic. Recent theory from the numerical solution of PDEs is adapted to show that a more appropriate characterization can be based upon pseudospectra instead of spectra. Numerical experiments with an adaptive ODE solver illustrate these findings.
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  • 62
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    BIT 34 (1994), S. 62-79 
    ISSN: 1572-9125
    Keywords: AMS(MOS) 65D30 ; 65B05 ; adaptive ; cubature ; singularity ; extrapolation ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract A new approach to the integration of vertex singularities is described. This approach is based on a non-uniform subdivision of the region of integration and the technique fits well to the subdivision strategy used in many adaptive algorithms. A nice feature with this approach is that it can be used in any dimension and on any region of integration which can be subdivided into subregions of the same form. The strategy can be applied both to vertex singularities and internal point singularities. In the latter case this can be done without an initial subdivision of the region in order to put the singular point in a vertex. It turns out that the technique has excellent numerical stability properties.
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  • 63
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    Aquatic sciences 52 (1990), S. 330-344 
    ISSN: 1420-9055
    Keywords: Flood ; phytoplankton succession ; reversion ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The effect of the August 1987 River Reuss flood event on the phytoplankton biocoenosis in Lake Uri (Urnersee, part of Lake Lucerne, Switzerland) was investigated firstly by comparing biological, chemical and physical data sampled before the event with equivalent data sampled after the event; and secondly by comparing the phytoplankton succession in 1987 with that occurring in the “floodfree” year 1989. As a consequence of the flood, the physical and chemical environment of the phytoplankton was found to have undergone a change which resulted in an alteration in the composition of the phytoplankton community. The phytoplankton community existing previous to the flood event, which had been dominated byTabellaria fenestrata sensu Husted 1930 (K-strategist), was replaced by a biocoenosis characterized mainly by various species of flagellates, which represent a typical spring successional stage (r-strategists). After the externally-imposed perturbation, the return to stable physical and chemical conditions was followed by the re-establishment of the successional stage which had existed before the flood (termed “reversion” by Reynolds, 1980).
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  • 64
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    Cellular and molecular life sciences 48 (1992), S. 1162-1164 
    ISSN: 1420-9071
    Keywords: Polygodial ; warburganal ; antifungal activity ; Candida albicans ; Saccharomyces cerevisiae ; Pityrosporum ovale ; enhancing effect ; antioxidants ; vitamin C ; BHA ; anethole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The antifungal activity of two drimane sesquiterpene dialdehydes, polygodial (1) and warburganal (2), alone and in combination with several other substances, was examined against three fungi,Candida albicans, Saccharomyces cerevisiae andPityrosporum ovale employing a broth dilution method. Anethole significantly synergized the activity of the two sesquiterpenoids againstC. albicans andS. cerevisiae however, it had only an, additive effect againstP. ovale. By contrast, two antioxidants, ascorbic acid (vitamin C) and BHA (butylated hydroxyanisole), noticeably enhanced the activity of the sesquiterpenoids againstP. ovale, but had no, effect againstC. albicans andS. cerevisiae.
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  • 65
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    Catalysis letters 28 (1994), S. 25-31 
    ISSN: 1572-879X
    Keywords: vanadia/alumina ; stability ; NO x selective reduction
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    Topics: Chemistry and Pharmacology
    Notes: Abstract Changes of the V2O5/Al3O3 catalyst aged for up to 10 years under real conditions of the selective catalytic reduction of NO x by ammonia (SCR) at the tail gases of the nitric acid plant were characterized by51V NMR spectroscopy, porosimetry, temperature programmed reduction (TPR) and catalytic activity measurements. The catalytic activity and the redox properties of the catalyst were found intact. Only small variations of the ratio of the octahedral and tetrahedral vanadia species were documented by51V NMR on aged catalyst.
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  • 66
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    Journal of industrial microbiology and biotechnology 7 (1991), S. 131-135 
    ISSN: 1476-5535
    Keywords: Saccharomyces cerevisiae ; Jerusalem artichoke ; High-fructose syrup ; Ethanol ; Immobilized yeast cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The results from this study showed that Jerusalem artichoke juice can be used for the production of very enriched fructose syrup by selective conversion of glucose to ethanol in a continuous process using immobilized cells ofSaccharomyces cerevisiae ATCC 36859. The product contained up to 99% of the total carbohydrates as fructose compared to 76% in the feed. Using Jerusalem artichoke juice supplemented with some glucose a product was obtained with 7.5% w/v ethanol which made ethanol recovery economically favourable. It was found that some fructose was consumed in these continuous processes; the glucose/fructose conversion rate ratio was regulated by the glucose concentration in the product stream.
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  • 67
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    Journal of industrial microbiology and biotechnology 7 (1991), S. 181-189 
    ISSN: 1476-5535
    Keywords: Saccharomyces cerevisiae ; Torulaspora delbrueckii ; Aroma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Thirty-three fermentations of Pedro Ximénez grapes, collected in three degrees of ripeness, were carried out by inoculation with three types of inoculum: pure cultures ofSaccharomyces cerevisiae races and ofTorulaspora delbrueckii, indigenous yeasts, and mixed cultures of indigenous yeasts enriched with the pure cultures. By means of variance analysis 21 compounds were determined whose final concentrations in the wines significantly depended on the musts, the inocula or both. Eleven products that depended significantly on the inocula were subjected to a discriminant analysis in which most of the pure cultures gathered in a discriminant space area different from that occupied by the indigenous yeasts. The centroids corresponding to most of the mixed cultures were shifted to the central area of the discriminant space, moved away from their corresponding pure cultures and approached the indigenous yeasts. The results show a high similarity between the fermentations carried out with mixed cultures with the addedS. cerevisiae races and those fermentations carried out with the indigenous yeasts, with regard to those compounds which were significantly dependent on the inocula.
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  • 68
    ISSN: 1432-0983
    Keywords: 2-oxoglutarate dehydrogenase ; Saccharomyces cerevisiae ; rad52-mediated chromosome loss
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    Topics: Biology
    Notes: Summary Ogd1 mutants of Saccharomyces cerevisiae are deficient in mitochondrial 2-oxoglutarate dehydrogenase activity; they cannot grow on glycerol and produce an increased amount of organic acids during growth on glucose as substrate. Using gamma ray-induced rad52-mediated chromosome loss the ogd1 mutation can be assigned to chromosome IX. Tetrad analysis of crosses between ogd1 and other markers on chromosome IX revealed that the OGD1 gene maps on the left arm of this chromosome 1.9 cM from his5.
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  • 69
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Orotate phosphoribosyl transferase ; Nucleotide sequence-5-phosphoribosyl 1-pyrophosphate (5PRPP)
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    Topics: Biology
    Notes: Summary Orotate phosphoribosyl transferase (OPRTase) catalyses the transformation of orotate to OMP in the pyrimidine pathway. In the yeast Saccharomyces cerevisiae, the URA5 gene is known to encode this enzyme activity. In this paper we present the cloning and sequencing of a yeast gene, named URA10, encoding a second OPRTase enzyme. Comparison of the predicted amino acid sequences between URA5 and URA10 genes shows more than 75% similarity. These sequences have also been compared to those of Escherichia coli, Podospora anserina, Sordaria macrospora and Dictyostelium discoideum. Remarkable similarities in the primary structure of these proteins have been found. Gene disruption experiments revealed that URA10 gene expression is responsible for the leaky phenotype of a ura5 mutant. Assays of OPRTase activity in extracts from ura5 and ura10 mutants indicate that the URA10 product contributes only 20% of the total activity found in wild type cells.
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  • 70
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Mutants ; Farnesyl diphosphate synthetase ; Ergosterol
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    Topics: Biology
    Notes: Summary Two yeast mutant strains auxotrophic for ergosterol and blocked in farnesyl diphosphate synthetase (EC 2.5.1.1) were isolated. Genetic analysis has shown that these mutant strains carry additional mutations in the ergosterol pathway besides erg20-1 and erg20-2 which affect FPP synthetase. The novel feature of these mutants is their ability to excrete prenyl alcohols (farnesol and geraniol). As geraniol is toxic for yeast cells, the above leaky mutations in FPP synthetase have to be associated with others in the sterol pathway, in order to slow down geraniol synthesis.
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  • 71
    ISSN: 1432-0983
    Keywords: Glucose oxidase ; Aspergillus ; Saccharomyces cerevisiae
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    Topics: Biology
    Notes: Summary We report the cloning of the Aspergillus niger glucose oxidase gene and its use to elevate glucose oxidase productivity in A. niger by increasing the gene dosage. In addition, the gene has been introduced into A. nidulans where it provides the novel capacity to produce glucose oxidase. A plasmid, in which DNA encoding the mature form of glucose oxidase was preceded by a Saccharomyces cerevisiae secretion signal, effected high-level production of extracellular glucose oxidase in this yeast.
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  • 72
    ISSN: 1432-0983
    Keywords: Schizosaccharomyces pombe ; Saccharomyces cerevisiae ; Argininosuccinate lyase ; Sequence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The complete nucleotide sequence of the ARG7 gene, coding for argininosuccinate lyase (EC 4.3.2.1), in the fission yeast (Schizosaccharomyces pombe) has been determined. It consists of an open reading frame of 461 codons. The deduced protein has a molecular weight of 51 200 Da. The gene is devoid of introns which is confirmed by the fact that it is expressed in Escherichia coli after spontaneous insertion of a bacterial sequence probably bearing a prokaryotic promoter. A perfect “TATA” box is found at-72 and the major transcription initiation site in Saccharomyces cerevisiae is located at-11 as shown by primer extension experiments. Comparison of the S. pombe lyase with related proteins from other organisms reveals an important degree of conservation except in the carboxyterminal part of the polypeptide. Additionally, a deletion removing 66 amino acids of the carboxy terminus yields an enzyme exhibiting some biological activity. A unique 1500 b transcript was found in S. cerevisiae when the intact gene was present, but the deleted version of the gene gave rise to at least three transcripts of 1800, 2800 and 3900 b.
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  • 73
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Pyrimidine salvage pathway ; Semi-dominant mutants ; FUR1 ; Uracil phosphoribosyl transferase ; Regulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary In Saccharomyces cerevisiae, the protein encoded by the FUR1 gene is absolutely required for the expression of uracil phosphoribosyl transferase activity. The occurrence of semi-dominant mutations for 5-fluorouracil-(5FU)-resistance at this locus led us to clone and sequence the semi-dominant fur 1–5 allele. A single point mutation, resulting in the substitution of arginine 134 for serine, is responsible for this mutant phenotype. The fur 1–5 allele is transcribed and expressed at the same level as the wild-type allele. But, in contrast with the wild-type, the UPR Tase activity of the fur 1–5 mutant strain is stimulated in vitro by UTP and does not, therefore, correspond to a loss of feedback of UPR Tase activity. We found that uracil, as a free base, induces a significative increase in transcription and UPR Tase activity in a wild-type strain as well as in uracil-overproducing mutants which principally explains the high efficiency of the pyrimidine salvage pathway in S. cerevisiae.
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  • 74
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    Current genetics 18 (1990), S. 401-403 
    ISSN: 1432-0983
    Keywords: Baking yeast ; Saccharomyces cerevisiae ; Dough leavening ; Benomyl
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary To investigate the leavening ability of yeast in dough, chromosome loss was induced by benomyl treatment in YOY1037, a diploid between a baking strain and a laboratory strain, and its effect on the leavening ability was studied. When benomyl-treated cells were spread on plates with a dye indicator for ploidy, about 20% of the visible colonies were stained dark blue or dark purple; the rest stained pale blue, similar to the diploid YOY1037. Strains showing the MATα phenotype, and non-galactose fermenting strains, apparently having lost particular chromosomes, were observed only in those with darkcoloured colonies. Strains with dark-coloured colonies showed a wider range of leavening ability than did those with pale-coloured colonies.
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  • 75
    ISSN: 1432-0983
    Keywords: Xylitol dehydrogenase gene ; Pichia stipitis ; Saccharomyces cerevisiae ; Xylose utilization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A P. stipitis cDNA library in λgt11 was screened using antisera against P. stipitis xylose reductase and xylitol dehydrogenase, respectively. The resulting cDNA clones served as probes for screening a P. stipitis genomic library. The genomic XYL2 gene was isolated and the nucleotide sequence of the 1089 bp structural gene, and of adjacent non-coding regions, was determined. The XYL2 open-reading frame codes for a protein of 363 amino acids with a predicted molecular mass of 38.5 kDa. The XYL2 gene is actively expressed in S. cerevisiae transformants. S. cerevisiae cells transformed with a plasmid, pRD1, containing both the xylose reductase gene (XYL1) and the xylitol dehydrogenase gene (XYL2), were able to grow on xylose as a sole carbon source. In contrast to aerobic glucose metabolism, S. cerevisiae XYL1-XYL2 transformants utilize xylose almost entirely oxidatively.
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  • 76
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Centromere flanking sequences ; tRNA modification enzymes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Transcriptional analysis of the region flanking the left boundary of the centromere of chromosome VI revealed the presence of a gene immediately adjacent to CEN6. The transcription of the gene is directed toward the centromere, and nucleotide sequence analysis showed that the coding region terminates only 50 bp away from CEN6. Our results extend to chromosome VI the observation that centromere-flanking regions of S. cerevisiae are transcriptionally active. Disruption of the coding region of the gene showed that its product, whilst not essential for cell viability, is important for normal cell growth. The gene has been termed DEG1 (DEpressed Growth rate). Comparison of the deduced amino acid sequence of DEG1 with a protein sequence databank revealed homology with the enzyme tRNA pseudouridine synthase I of E. coli.
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  • 77
    ISSN: 1432-0983
    Keywords: Mutagen hyper-resistance ; Nitrogen mustard ; Saccharomyces cerevisiae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A screening of haploid yeast strains for enhanced resistance to nitrogen mustard (HN2) yielded a recessive mutant allele, hnm1, that conferred hyper-resistance (HYR) to HN2. Diploids, homo- or heterozygous for the HNM1 locus, exhibit normal wild-type like resistance while homozygosity for hnm1 leads to the phenotype HYR to HN2. The hnm1 mutation could be found in yeast strains proficient or deficient in different DNA repair systems. In these mostly HN2-sensitive haploid repair-deficient mutants, hnm1 acted as a partial suppressor of HN2 sensitivity. All isolated recessive mutations conferring hyper-resistance belonged to a single complementations group. The HYR to HN2 phenotype was maximally expressed in growing cells and was associated with reduced mutability by HN2. HNM1 most probably controls uptake of HN2 which would be impaired in the hnm1 mutants.
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  • 78
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; G418 resistance ; Gene cartridges ; Heterologous Gene expression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Coding sequence cartridges for aminoglycoside phosphotransferase (APT) were isolated from bacterial transposon Tn903. When incorporated into a heterologous gene construction utilising the PGK1 promoter and terminator, the heterologous APT gene provided a G418-resistance determinant that functioned efficiently as a dominant marker for yeast in both multiple- and single-copy. Transformant colonies on selective medium appeared rapidly, within 36–48 h, and growth rate of the transformed cells was normal. A simple and highly sensitive radiolabelling assay for APT enzyme activity was developed for use with crude cell protein extracts. Enzyme activity units were equated to the amount of APT protein present in the cells, and the APT protein was shown to be stable in yeast. Heterologous APT expression was 130-fold reduced compared with homologous PGK1. This resulted from an estimated two-fold decrease in mRNA level and a 65-fold decrease in translation efficiency. The latter was unaffected by AUG sequence context change, but corresponded with a high frequency of minor codons in the APT-coding sequence. APT can be used as a semi-quantitative reporter of gene expression, whose useful features are in vivo detection via the G418-resistance phenotype and powerful cell-free assay.
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    Current genetics 19 (1991), S. 9-14 
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Mevalonate kinase ; Ergosterol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The nucleotide sequence of the ERG12 gene, encoding mevalonate kinase, from Saccharomyces cerevisiae is presented. The longest open reading frame may code for a protein containing 443 amino acids with a deduced relative molecular mass of 48 500. The analysis of the nucleotide sequence reveals a complete identity with the yeast gene RAR1, isolated elsewhere by complementation of a rar1 mutation involved in the stability of plasmids with weak ARS. In addition, we show that mevalonate kinase is not a rate-limiting enzyme; however its sensitivity to FFP could be a key regulatory mechanism in the sterol pathway of yeast.
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  • 80
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Episomal plasmid ; Copy number control ; Plasmid maintenance ; Glycolytic enzyme levels
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary This study demonstrates how varying the promoter strength of an essential gene on a yeast 2μORI-STB YEp multicopy vector can influence vector copy levels. A phosphoglycerate kinase gene (PGK) on this plasmid was made essential for fermentative growth by transformation into a pgk - yeast strain. When in these PGK- transformants the requirement for PGK expression was the sole selective criterion for plasmid maintenance, PGK promoter activity was inversely related to vector copy levels. Plasmids with an efficiently-transcribed PGK gene were maintained at approximately one copy per cell, whereas those lacking the UAS that normally directs high basal PGK transcription levels were present at up to 10–15 copies. All cultures of these PGK+ transformants contained only a low proportion of pgk - cells. Since mitotic loss of the plasmid arrests growth through loss of a functional PGK allele, PGK confers high stability to the YEp vector in such a pgk - genetic background. In this system YEp vector levels are probably influenced by PGK transcription because high expression of PGK is needed in rapid fermentative growth. Remarkably, low plasmid PGK promoter activity caused PGK mRNA levels slightly higher than those found in yeast with normal PGK regulation. A higher plasmid copy number is therefore not the only factor counteracting the effects of low PGK transcription, and it is possible that PGK mRNA becomes more stable in response to inefficient PGK transcription.
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  • 81
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Sporulation ; Inessential genes ; Genome organization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The SPR6 gene of Saccharomyces cerevisiae encodes a moderately abundant RNA that is present at high levels only during sporulation. The gene contains a long open reading frame that could encode a hydrophilic protein approximately 21 kDa in size. This protein is probably produced by the yeast, because the lacZ gene of Escherichia coli is expressed during sporulation when fused to SPR6 in the expected reading frame. SPR6 is inessential for sporulation; mutants that lack SPR6 activity sporulate normally and produce viable ascospores. Nonetheless, the SPR6 gene encodes a function that is relevant to sporulating cells; the wild-type allele can enhance sporulation in strains that are defective for several SPR functions. SPR6 is located on chromosome V, 14.4 centimorgans centromere-distal to MET6.
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  • 82
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Nucleo-mitochondrial interactions ; Mitochondrial status ; Lycorine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary In a previous paper we have shown that the alkaloid lycorine inhibits growth of rho +, mit - and rho -, strains of Saccharomyces cerevisiae, whereas strains devoid of mitochondrial DNA (rho o) are resistant to more than 200 μg/ml of the alkaloid. In this report we show that hypersuppressive petites are almost as resistant as rho o mutants, whereas isogenic rho - petites, which have retained tained longer segments of the genome, are sensitive to the drug.
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  • 83
    ISSN: 1432-0983
    Keywords: Schizosaccharomyces pombe ; Saccharomyces cerevisiae ; CaMV 35S promoter ; CaMV 35S terminator ; Heterologous expression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Complementation of fission yeast mutants by plant genomic libraries could be a promising method for the isolation of novel plant genes. One important prerequisite is the functioning of plant promoters and terminators in Schizosaccharomyces pombe and Saccharomyces cerevisiae. Therefore, we studied the expression of the bacterial β-glucuronidase (GUS) reporter gene under the control of the Cauliflower Mosaic Virus (CaMV) 35S promoter and 35S terminator. We show here that S. pombe initiates transcription at exactly the same start site as was reported for tobacco. The 35S CaMV terminator is appropriately recognized leading to a polyadenylated mRNA of the same size as obtained in plant cells transformed with the same construct. Furthermore, the GUS-mRNA is translated into fully functional GUS protein, as determined by an enzymatic assay. Interestingly, expression of the 35S promoter in the budding yeast S. cerevisiae was found to be only moderate and about hundredfold lower than in S. pombe. To investigate whether different transcript stabilities are responsible for this enormous expression difference in the two yeasts, the 35S promoter was substituted by the ADH (alcohol dehydrogenase) promoter from fission yeast. In contrast to the differential expression pattern of the 35S promoter, the ADH promoter resulted in equally high expression rates in both fission and budding yeast, comparable to the 35S promoter in S. pombe. Since the copy number of the 35S-GUS constructs differs only by a factor of two in the two yeasts, it appears that differential recognition of the 35S promoter is responsible for the different transcription rates.
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  • 84
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Mitochondria ; Intron-encoded proteins ; Recombination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The respiratory competency of a yeast strain devoid of mitchondrial introns is quite normal. However, it may be asked whether intron-encoded proteins participate in metabolisms other than those of mitochondrial introns. Using strains without mitochondrial introns we have answered two questions. The first was: does the absence of intron-encoded proteins abolsh mitochondrial recombination? The second was: do mitochondrial introns and intron-encoded proteins play a part in mitochondrial DNA rearrangements induced by ethidium bromide (rho- production)? We have shown that the introns and intron-encoded proteins are not essential essential components of either phenomenon.
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    Current genetics 18 (1990), S. 23-27 
    ISSN: 1432-0983
    Keywords: Protein translocation ; Saccharomyces cerevisiae ; Peroxisomes ; Overexpression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Import of proteins into organelles usually requires a cis-acting targeting signal. Analysis of various hybrid proteins, consisting of mouse DHFR and parts of catalase A from Saccharomyces cerevisiae, revealed that fusion proteins containing the N-terminal 126 amino acids, or less, of catalase A remain in the cytosol whereas fusion proteins containing 140, or more, N-terminal amino acids of catalase A form large aggregates inside the cell. These protein bodies, which lack a surrounding membrane, copurified with peroxisomes on cell fractionation. The peroxisomal targeting signal of catalase A does not reside at the C-terminus or at the N-terminus.
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  • 86
    ISSN: 1432-1432
    Keywords: Thiolase ; Peroxisome evolution ; Bootstrap analysis ; Saccharomyces cerevisiae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The thiolase family is a widespread group of proteins present in prokaryotes and three cellular compartments of eukaryotes. This fact makes this family interesting in order to study the evolutionary process of eukaryotes. Using the sequence of peroxisomal thiolase from Saccharomyces cerevisiae recently obtained by us and the other known thiolase sequences, a phylogenetic analysis has been carried out. It shows that all these proteins derived from a primitive enzyme, present in the common ancestor of eubacteria and eukaryotes, which evolved into different specialized thiolases confined to various cell compartments. The evolutionary tree obtained is compatible with the endosymbiotic theory for the origin of peroxisomes.
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    Journal of molecular evolution 38 (1994), S. 363-368 
    ISSN: 1432-1432
    Keywords: Saccharomyces cerevisiae ; 2-μm circle ; DNA sequencing ; Horizontal transmission ; Site-specific recombination ; Selfish DNA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We compared the nucleotide substitution pattern over the entire genome of two unique variants of the 6,300-bp selfish DNA (2 μm) plasmid in Saccharomyces cerevisiae. The DNA sequence of the left-unique region is identical among 2-μm variants, while the right-unique region shows substantial divergence. This chimeric pattern cannot be explained by neutral or Darwinian selection models. We propose that horizontal transmission of the 2-μm plasmid coupled with a directed, polarized gene conversion maintains the DNA sequence of the left-unique region, whereas the right-unique region is subject to random drift and Darwinian selection.
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  • 88
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    OR spectrum 15 (1994), S. 197-203 
    ISSN: 1436-6304
    Keywords: Inventory ; dynamic programming ; stability ; Lagerhaltung ; Dynamische Optimierung ; Stabilität
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Description / Table of Contents: Zusammenfassung Die Menge der Kostenparameter, für die eine optimale Lösung des dynamischen Losgrößenmodells optimal bleibt wird hier Stabilitätsregion genannt. Die Größe einer solchen Menge kann als Maß der Robustheit einer Lösung angesehen werden. Es ist zu erwarten, daß die Stabilitätsregionen mit wachsendem Zeithorizont schrumpfen und daß sie in diesem Sinne monoton sind. In der vorliegenden Arbeit werden verschiedene hinreichende Bedingungen für diese Monotonie untersucht. Die Bedingungen setzen unter anderem die Existenz von Planungs- und Vorhersage-Horizonten voraus und verallgemeinern so Ergebnisse einer früheren Arbeit, in der Aussagen für gewöhnliche Planungs-Horizonte vorgestellt wurden.
    Notes: Abstract The set of cost inputs for which an optimal solution of the dynamic lot size model remains valid is called stability region. The size of this region may be viewed as a measure of robustness of a solution. It is an expectation that the stability regions shrink with growing time horizons and that they are monotonous in this sense. In the present paper several sufficient conditions implying monotonicity will be studied. The conditions cover the existence of planning and forecast horizons and generalize the results of a previous paper in wich monotonicity results were presented for the case of ordinary planning horizons.
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    Microchimica acta 104 (1991), S. 467-482 
    ISSN: 1436-5073
    Keywords: prediction ; stability ; multivariate methods ; graphical analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Sizeable data bases are now being routinely generated in a variety of contexts in chemical industry. Statistical investigations of such data bases are aimed both at initially uncovering structure and eventually proposing models, in particular for predicting product quality by the mix or characteristics of the chemical compounds. “Online Multivariate Exploratory Graphical Analysis” (OMEGA) stands for a structured exploratory study of the relationships in a multivariate data set, where, rather than testing for one specific property, as many clues as possible for interesting structures are searched for by different dimension reductions and succeeding interactive graphical analyses. The stability of the projections obtained by the different dimension reduction methods is assessed by simulation producing graphical displays particularly supporting the identification of influential points. The variation of the predictions obtained by the different dimension reduction methods is assessed by cross-validation delivering misclassification rates or cross-validated R2 values. The interpretation of the new coordinates corresponding to dimension reduction is supported by loading simplifications and graphical displays for judging its adequacy. The OMEGA strategy has been found to be an effective tool for routine searching for structure.
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    Meccanica 29 (1994), S. 195-210 
    ISSN: 1572-9648
    Keywords: Chetaev functional ; pendulum ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Sommario Si considera il problema di stabilità di punti di equilibrio di un pendolo fisico con un filo inestensibile appeso ad esso dal punto di vista del teorema di Lagrange sulla stabilità e sulla sua inversione. Difficoltà specifiche relative allo studio di un sistema meccanico di dimensione infinita sono discusse. Si suggerisce un nuovo metodo per lo studio della stabilità rispetto a due metriche. L'influenza di fenomeni di risonanza sul moto del sistema ridotto (linearizzato) è considerata.
    Notes: Abstract The problem of stability of equilibria of a physical pendulum with a nonstretchable thread attached to it is considered from the standpoint of the Lagrange theorem on stability and its inversion. Specific difficulties which one faces when studying an infinite dimensional mechanical system are discussed. A new approach to the study of stability with respect to two metrics is suggested. The influence of resonant phenomena on the motion of the shortened (linearized) system is considered.
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    Journal of intelligent and robotic systems 3 (1990), S. 259-289 
    ISSN: 1573-0409
    Keywords: Nonlinear decoupling ; feedback linearization ; functional analysis ; elastic robots ; robustness ; stability ; pole assignment ; nonlinear systems ; robot control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A robustness analysis and synthesis for incomplete nonlinear decoupling for a class of nonlinear systems is discussed. Rigid and elastic-joint robot models belong to this class. For the elastic case, a transformation facilitates the robustness analysis under a weak assumption. Charts with H 1- and H ∞- norms of closed-loop disturbance transfer functions of the nonlinear-decoupled system are presented for a robust pole assignment.
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    Journal of intelligent and robotic systems 6 (1992), S. 51-63 
    ISSN: 1573-0409
    Keywords: Scheduling ; flexible manufacturing systems ; stability ; feedback
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A genetic manufacturing environment is considered. The emphasis is on small-lot, discrete, and asynchronous type of manufacturing systems rather than high volume and continuous type. Two classes of scheduling policies are proposed to render the machine stable. The policies are of feedback type. The decision is made in real-time and on-line.
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    Journal of intelligent and robotic systems 6 (1992), S. 219-240 
    ISSN: 1573-0409
    Keywords: Force control ; slip-stick friction ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract This paper explores two practical issues related to the force control of manipulators. The first issue examined is how system stability is effected by commonly occurring manipulator nonlinearities, such as sampled-data, control signal saturation and slip-stick friction. It is shown that discretely implemented force control algorithms can drive the feedback force controlled manipulator into a limit cycle, even for a very small sampling period that by far satisfies Shannon's sampling theorem. The bounds of stability are enhanced by the presence of control signal saturation and slip stick friction. The second issue investigated is the inclusion of a high gain inner position loop as a means to minimize the unpredictability in the steady state error due to slip-stick friction. In order to support the theoretical conclusions, experiments were performed with the PUMP 560 industrial robot testbed facility developed at Colorado State University.
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    K-Theory 4 (1991), S. 363-397 
    ISSN: 1573-0514
    Keywords: Nonabelian K 1 ; noncommutative homotopy ; general linear group ; superspecial linear groups ; descending central series ; stability ; relative normal subgroups ; nilpotent sandwich classifications ; quasi-finite algebras
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract A functorial filtration GL n =S−1L n $$ \supseteq$$ S0L n $$ \supseteq$$ ⋯ $$ \supseteq$$ S i L n $$ \supseteq$$ ⋯ $$ \supseteq$$ E n of the general linear group GL n, n ⩾ 3, is defined and it is shown for any algebra A, which is a direct limit of module finite algebras, that S−1 L n (A)/S0L n (A) is abelian, that S0L n (A) $$ \supseteq$$ S1L n (A) $$ \supseteq$$ ⋯ is a descending central series, and that S i L n (A) = E n(A) whenever i ⩾ the Bass-Serre dimension of A. In particular, the K-functors k 1 S i L n =S i L n /E n are nilpotent for all i ⩾ 0 over algebras of finite Bass-Serre dimension. Furthermore, without dimension assumptions, the canonical homomorphism S i L n (A)/S i+1 L n (A)→S i L n+ 1(A)/S i+1 L n + 1 (A) is injective whenever n ⩾ i + 3, so that one has stability results without stability conditions, and if A is commutative then S0L n (A) agrees with the special linear group SL n (A), so that the functor S0L n generalizes the functor SL n to noncommutative rings. Applying the above to subgroups H of GL n (A), which are normalized by E n(A), one obtains that each is contained in a sandwich GL′ n (A, ρ) $$ \supseteq$$ H $$ \supseteq$$ E n(A, ρ) for a unique two-sided ideal ρ of A and there is a descending S0L n (A)-central series GL′ n (A, ρ) $$ \supseteq$$ S0L n (A, ρ) $$ \supseteq$$ S1L n (A, ρ) $$ \supseteq$$ ⋯ $$ \supseteq$$ S i L n (A, ρ) $$ \supseteq$$ ⋯ $$ \supseteq$$ E n(A, ρ) such that S i L n (A, ρ)=E n(A, ρ) whenever i ⩾ Bass-Serre dimension of A.
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    K-Theory 7 (1993), S. 333-367 
    ISSN: 1573-0514
    Keywords: Locally flat embedding ; pointed Hermitian module ; splitting ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract We prove an existence result for topologically locally flat embeddings of 2-spheres in simply connected 4-manifolds. This topological result is deduced from a splitting theorem for pointed Hermitian modules over a cyclic group ring. A stability result for such modules is also proved. This applies to the isotopy classification of locally flat embeddings.
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    Multidimensional systems and signal processing 3 (1992), S. 421-425 
    ISSN: 1573-0824
    Keywords: Convex combination ; polynomial ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract A sufficient condition for Hurwitz stability of a convex combination of two stable polynomials is obtained.
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  • 97
    ISSN: 1573-0832
    Keywords: Nystatin ; amphotericin B ; amphotericin B methyl ester ; polyene antibiotics ; yeast ; Saccharomyces cerevisiae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Saccharomyces cerevisiae was cultured under anaerobiosis in semi-complete medium to which either palmitoleic or oleic acid was added. Cells were grown at 20 °C or 30 °C. The levels of total lipids, total sterols, and phospholipids were higher in cells grown at 20 °C than at 30 °C. The effects of nystatin (NYS), amphotericin B (AMB), and amphotericin B methyl ester (AME) were evaluated by determining cell viability and liberation of intracellular compounds. The loss of cell viability is higher in the first 30 minutes of incubation with the drugs and is the same regardless of the type of cells obtained. Low molecular weight compounds and ions such as K+ are liberated a few minutes after incubation with the drugs whereas proteins and substances absorbing at 260 nm are liberated later. Phosphate liberation comes after K+ and before compounds of higher molecular weights.
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    Nutrient cycling in agroecosystems 32 (1992), S. 61-70 
    ISSN: 1573-0867
    Keywords: Pig slurry ; processing ; relative efficiency index ; N ; P ; K ; organic carbon ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract In the Netherlands, pig slurries are processed to improve their fertilizer value as well as handling and application. The relative efficiency index (REI) of N, P and K and the stability of organic carbon (C) in test products of processed pig slurries (PPS) were determined in pot and incubation experiments. The dry and easily manageable PPS were produced according to the Promest procedure. The mineral fraction of total N varied from 60 to 88%. It consisted mainly of nitrate. About 25% of the organic N was rapidly mineralized. The REI of N varied from 66 to 92%. After application REI of P from pelletized PPS varied from 41 to 62% in the first half year. The REI of P in ground but non-pelletized PPS varied from 81 to 100%. The REI of K was estimated to be 100%. PPS contained less easily decomposable organic C than untreated pig slurry due to the anaerobic digestion step in the processing procedure. About 34% of the organic C disappeared as methane and carbon dioxide during processing. It was concluded that processing improved the fertilizer value of PPS compared with that of untreated pig slurry.
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    Multidimensional systems and signal processing 4 (1993), S. 91-101 
    ISSN: 1573-0824
    Keywords: Bilinear transformation ; polynomial ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract The paper presents a unified approach to calculation, for a given, nominal,G-stable polynomial, a corresponding stability region in the space of perturbed coefficients
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    Multidimensional systems and signal processing 4 (1993), S. 331-354 
    ISSN: 1573-0824
    Keywords: two-dimensional discrete-time systems ; two-dimensional digital filters ; bivariate polynomials ; stability ; Bistritz tabular form ; Jury tabular form ; Schur-Cohn minors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract In determining root distribution of univariate polynomials with real or complex-valued coefficients, the Bistritz tabular form offers a significant computational advantage. Stability studies of two-dimensional (2-D) discrete-time systems involve univariate polynomials possessing parameter-dependent coefficients, where the parameter takes values on the unit circle in the complex plane. This paper investigates the application of Bistritz tabular form in determining stability of 2-D discrete-time systems, and for this purpose we present two algorithms. Both algorithms utilize a recent result that has established the relationship between Schur-Cohn minors and the entries of the Bistritz tabular form corresponding to a given polynomial. A comparison between the use of the modified Jury table and the Bistritz table in stability checking of 2-D discrete-time systems is also presented.
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