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Monogamy with a purpose [Opinion] (2013)

de Waal, F. B. M., Gavrilets, S.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-09-18

Description: Humans are fascinated by animal monogamy. In the 1960s, Konrad Lorenz idealized the lifelong pair-bonds of geese until one of his students pointed out some infidelities and suggested that geese may be “only human” (1), and Desmond Morris (2) speculated about the advantages of the pair-bond for early humans. Even...

Keywords: Opinions

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

Published by National Academy of Sciences

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FimH conformation and virulence [Microbiology] (2013)

Schwartz, D. J., Kalas, V., Pinkner, J. S., Chen, S. L., Spaulding, C. N., Dodson, K. W., Hultgren, S. J.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-09-25

Description: Chaperone–usher pathway pili are a widespread family of extracellular, Gram-negative bacterial fibers with important roles in bacterial pathogenesis. Type 1 pili are important virulence factors in uropathogenic Escherichia coli (UPEC), which cause the majority of urinary tract infections (UTI). FimH, the type 1 adhesin, binds mannosylated glycoproteins on the surface...

Keywords: Inaugural Articles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

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Glucose and willpower [Psychological and Cognitive Sciences] (2013)

Job, V., Walton, G. M., Bernecker, K., Dweck, C. S.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-09-11

Description: Past research found that the ingestion of glucose can enhance self-control. It has been widely assumed that basic physiological processes underlie this effect. We hypothesized that the effect of glucose also depends on people’s theories about willpower. Three experiments, both measuring (experiment 1) and manipulating (experiments 2 and 3) theories...

Keywords: Inaugural Articles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

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Profile of John J. Eppig [Profiles] (2013)

Griswold, A.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-09-25

Description: On a spring afternoon in 1955, a 12-year-old boy hurried home on the well-trod path from school. As he dashed past the ponds of Long Island’s North Shore and rounded Shelter Rock, his thoughts turned to the collection of jars waiting in his bedroom, each one filled with water from...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

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Profile of Scott J. Hultgren [Profiles] (2013)

Zeliadt, N.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-09-25

Description: During her lifetime, an adult woman has a 50% chance of developing a urinary tract infection—one of the most common types of infections (1). Most urinary tract infections are caused by strains of the bacterium Escherichia coli, and, for the most part, are easily treated with antibiotics. However, many of...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

Topics: Biology , Medicine , Natural Sciences in General

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Top-down activations in conceptual knowledge [Neuroscience] (2013)

Avanzini, P., Fabbri-Destro, M., Campi, C., Pascarella, A., Barchiesi, G., Cattaneo, L., Rizzolatti, G.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-10-02

Description: It is generally accepted that visual perception results from the activation of a feed-forward hierarchy of areas, leading to increasingly complex representations. Here we present evidence for a fundamental role of backward projections to the occipito-temporal region for understanding conceptual object properties. The evidence is based on two studies. In...

Keywords: Inaugural Articles

Print ISSN: 0027-8424

Electronic ISSN: 1091-6490

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2012 Nobel Laureates in Medicine or Physiology [Profiles] (2013)

Colman, A.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-04-10

Description: We celebrate the 2012 Nobel Prize for Medicine awarded to Sir John Gurdon and Shinya Yamanaka for their groundbreaking contributions to the field of cell reprogramming. In 1962, in a series of experiments inspired by Briggs and King (1), Gurdon demonstrated that the nucleus of a frog somatic cell could...

Keywords: PNAS Profiles

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2012 Nobel Laureates in Chemistry [Profile] (2013)

Clark, R. B.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-04-03

Description: Those of us that had been hammering away in the field for 40 years or more cannot deny the excitement in learning that Brian Kobilka, a former postdoctoral fellow of Robert Lefkowitz, in collaboration with Roger Sunahara, had determined the structure of the agonist-bound β2-adrenergic receptor-Gs protein complex (1). To...

Keywords: PNAS Profiles

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Electronic ISSN: 1091-6490

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Profile of Janet Hemingway [Profile] (2013)

Griswold, A.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-04-03

Description: As the wheels of a biplane approach a desolate airfield in the Solomon Islands, a man wearing only a loincloth breaks through the brush, brandishing a spear and a flail. From behind the plane’s windows four biologists watch with wary eyes and silently map an escape route. “You’re thinking, ‘What...

Keywords: PNAS Profiles

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Brown and Goldstein: The cholesterol chronicles [Classic Profile] (2013)

Nair, P.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publication Date: 2013-09-11

Description: When his parents took three-year-old John Despota to his primary care physician in Chicago in 1964, orange-tinted fat-laden bumps lined the skin on the back of his lower legs. Eruptions caused by excess cholesterol, the bumps spread across Despota’s body, mirroring a total blood cholesterol level that hovered above six-times...

Keywords: PNAS Profiles

Print ISSN: 0027-8424

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