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  • bacteriophagesgenome deliveryfusion proteinsRNA-dependent RNA polymerasesviral proteasesviral receptorsviruses  (1)
  • biological solution small-angle X-ray scattering (BioSAXS)synchrotron radiationbeamlinesstructural complexitybiostructural research  (1)
  • dioxygenaseshistone demethylationDNA/RNA demethylationN6-methyladenosineALKBH5  (1)
  • International Union of Crystallography (IUCr)  (3)
  • EMBO Press
  • Essen : Verl. Glückauf
  • Krefeld : Geologischer Dienst Nordhein-Westfalen
  • 2010-2014  (3)
  • 2005-2009
Sammlung
Schlagwörter
Verlag/Herausgeber
  • International Union of Crystallography (IUCr)  (3)
  • EMBO Press
  • Essen : Verl. Glückauf
  • Krefeld : Geologischer Dienst Nordhein-Westfalen
Erscheinungszeitraum
  • 2010-2014  (3)
  • 2005-2009
Jahr
  • 1
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    Viruses and viral proteins (2014)
    International Union of Crystallography (IUCr)
    In: IUCrJ
    Details
    Publikationsdatum: 2014-11-12
    Beschreibung: For more than 30 years X-ray crystallography has been by far the most powerful approach for determining the structures of viruses and viral proteins at atomic resolution. The information provided by these structures, which covers many important aspects of the viral life cycle such as cell-receptor recognition, viral entry, nucleic acid transfer and genome replication, has extensively enriched our vision of the virus world. Many of the structures available correspond to potential targets for antiviral drugs against important human pathogens. This article provides an overview of the current knowledge of different structural aspects of the above-mentioned processes.
    Schlagwort(e): bacteriophagesgenome deliveryfusion proteinsRNA-dependent RNA polymerasesviral proteasesviral receptorsviruses
    Digitale ISSN: 2052-2525
    Thema: Geologie und Paläontologie , Physik
    Publiziert von International Union of Crystallography (IUCr)
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    AKTUELLE ARTIKEL
  • 2
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    Investigating increasingly complex macromolecular systems with small-angle X-ray scattering (2014)
    International Union of Crystallography (IUCr)
    In: IUCrJ
    Details
    Publikationsdatum: 2014-11-12
    Beschreibung: The biological solution small-angle X-ray scattering (BioSAXS) field has undergone tremendous development over recent decades. This means that increasingly complex biological questions can be addressed by the method. An intricate synergy between advances in hardware and software development, data collection and evaluation strategies and implementations that readily allow integration with complementary techniques result in significant results and a rapidly growing user community with ever increasing ambitions. Here, a review of these developments, by including a selection of novel BioSAXS methodologies and recent results, is given.
    Schlagwort(e): biological solution small-angle X-ray scattering (BioSAXS)synchrotron radiationbeamlinesstructural complexitybiostructural research
    Digitale ISSN: 2052-2525
    Thema: Geologie und Paläontologie , Physik
    Publiziert von International Union of Crystallography (IUCr)
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    AKTUELLE ARTIKEL
  • 3
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    Unbekannt
    Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation (2014)
    International Union of Crystallography (IUCr)
    In: IUCrJ
    Details
    Publikationsdatum: 2014-11-12
    Beschreibung: Iron(II) and 2-oxoglutarate (2OG)-dependent dioxygenases involved in histone and DNA/RNA demethylation convert the cosubstrate 2OG and oxygen to succinate and carbon dioxide, resulting in hydroxylation of the methyl group of the substrates and subsequent demethylation. Recent evidence has shown that these 2OG dioxygenases play vital roles in a variety of biological processes, including transcriptional regulation and gene expression. In this review, the structure and function of these dioxygenases in histone and nucleic acid demethylation will be discussed. Given the important roles of these 2OG dioxygenases, detailed analysis and comparison of the 2OG dioxygenases will guide the design of target-specific small-molecule chemical probes and inhibitors.
    Schlagwort(e): dioxygenaseshistone demethylationDNA/RNA demethylationN6-methyladenosineALKBH5
    Digitale ISSN: 2052-2525
    Thema: Geologie und Paläontologie , Physik
    Publiziert von International Union of Crystallography (IUCr)
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    AKTUELLE ARTIKEL
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