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  • 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk  (4)
  • Xenopus laevis  (4)
  • Elsevier  (6)
  • EGU  (1)
  • Frontiers Media  (1)
  • American Institute of Physics (AIP)
  • 2015-2019  (8)
  • 1
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    Uncovering deformation processes from surface displacements (2016)
    Elsevier
    Details
    Publication Date: 2021-05-12
    Description: Today, satellite remote sensing has reached a key role in Earth Sciences. In particular, Synthetic ApertureRadar (SAR) sensors and SAR Interferometry (InSAR) techniques are widely used for the study of dynamicprocesses occurring inside our living planet. Over the past 3 decades, InSAR has been applied for mappingtopography and deformation at the Earth’s surface. These maps are widely used in tectonics, seismology,geomorphology, and volcanology, in order to investigate the kinematics and dynamics of crustal faulting,the causes of postseismic and interseismic displacements, the dynamics of gravity driven slope failures,and the deformation associated with subsurface movement of water, hydrocarbons or magmatic fluids.
    Description: Published
    Description: 58-82
    Description: 1T. Geodinamica e interno della Terra
    Description: 4T. Fisica dei terremoti e scenari cosismici
    Description: 3V. Dinamiche e scenari eruttivi
    Description: JCR Journal
    Description: reserved
    Keywords: SAR ; InSAR ; Earth observation ; Surface displacements ; Satellite missions ; Advanced InSAR ; Earthquake studies ; Volcanic studies ; Tectonic process ; Coseismic studies ; Soil liquefaction ; Post-seismic studies ; Interseismic studies ; Volcanic unrest ; Pre-eruptive phase ; Eruptive phase ; 04. Solid Earth::04.03. Geodesy::04.03.01. Crustal deformations ; 04. Solid Earth::04.03. Geodesy::04.03.06. Measurements and monitoring ; 04. Solid Earth::04.03. Geodesy::04.03.07. Satellite geodesy ; 04. Solid Earth::04.03. Geodesy::04.03.09. Instruments and techniques ; 04. Solid Earth::04.06. Seismology::04.06.03. Earthquake source and dynamics ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk ; 04. Solid Earth::04.07. Tectonophysics::04.07.07. Tectonics
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 2
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    Geoethics: ethical challenges and case studies in Earth Science (2015)
    Elsevier
    Details
    Publication Date: 2017-04-04
    Description: Key Features. Written by a global group of contributors with backgrounds ranging from philosopher to geo-practitioner, providing a balance of voices. Includes case studies, showing where experts have gone wrong and where key organizations have ignored facts, wanting assessments favorable to their agendas. Provides a much needed basis for discussion to guide scientists to consider their responsibilities and to improve communication with the public. Description. Edited by two experts in the area, Geoethics: Ethical Challenges and Case Studies in Earth Sciences addresses a range of topics surrounding the concept of ethics in geoscience, making it an important reference for any Earth scientist with a growing concern for sustainable development and social responsibility. This book will provide the reader with some obvious and some hidden information you need for understanding where experts have not served the public, what more could have been done to reach and serve the public and the ethical issues surrounding the Earth Sciences, from a global perspective. Table of contents. Section 1: Introduction Section 2: Philosophical reflections Section 3: The ethics of practice Section 4: Man made hazards Section 5: Natural hazards Section 6: Exploitation of resources Section 7: Low income and indigenous communities Section 8: Geoscience community
    Description: Published
    Description: 3T. Pericolosità sismica e contributo alla definizione del rischio
    Description: 5T. Sorveglianza sismica e operatività post-terremoto
    Description: 4V. Vulcani e ambiente
    Description: 5V. Sorveglianza vulcanica ed emergenze
    Description: 4A. Clima e Oceani
    Description: 6A. Monitoraggio ambientale, sicurezza e territorio
    Description: open
    Keywords: Geoethics ; Philosophy ; Natural hazards ; Man made hazards ; Georesources ; Low income countries ; Geoscience community ; Communication ; Geoeducation ; Natural risks ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk ; 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk ; 05. General::05.03. Educational, History of Science, Public Issues::05.03.99. General or miscellaneous ; 05. General::05.08. Risk::05.08.99. General or miscellaneous ; 05. General::05.09. Miscellaneous::05.09.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: book
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  • 3
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    Seismic damage to pipelines in the framework of Na-Tech risk assessment (2015)
    Elsevier
    Details
    Publication Date: 2020-05-29
    Description: The structural integrity of pipelines undergone seismic waves is crucial for industrial installation and for the distributed transportation networks of gaseous and liquid fluids. However, it is nowadays proved that the definition of seismic vulnerability based on purely, structural-derived limit states or on return-to-service or even on the purely economic repair rate indications, is not sufficient for the holistic analysis of risks. On the other hand, detailed numerical studies based on full analyses (including fluid/soil/structure interaction) are too expensive for the aims of risk assessment and simplified methodologies are still needed.In this paper, a large database of earthquake-induced damage for steel and non-steel pipelines is presented. Each case was analyzed and collected from post-earthquake reconnaissance, seismic engineering reports and technical papers. The database may be adopted for the definition of specific vulnerability function (fragility curves), which are commonly implemented in multi-hazard analyses, and more in general for the assessment of Na-Tech risks (Natural events triggering Technological disasters). Seismic damage to pipelines in the framework of Na-Tech risk assessment. Available from: https://www.researchgate.net/publication/271673585_Seismic_damage_to_pipelines_in_the_framework_of_Na-Tech_risk_assessment [accessed Jun 12, 2015].
    Description: Published
    Description: 159-162
    Description: 3T. Pericolosità sismica e contributo alla definizione del rischio
    Description: JCR Journal
    Description: restricted
    Keywords: Earthquake ; Na-Tech ; Ground failure ; Lifeline ; Fragility curve ; Pipelines ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 4
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    Generation of a Xenopus laevis F1 albino J strain by genome editing and oocyte host-transfer (2017)
    Elsevier
    Details
    Publication Date: 2022-05-25
    Description: © The Author(s), 2016. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Developmental Biology 426 (2017): 188–193, doi:10.1016/j.ydbio.2016.03.006.
    Description: Completion of the Xenopus laevis genome sequence from inbred J strain animals has facilitated the generation of germline mutant X. laevis using targeted genome editing. In the last few years, numerous reports have demonstrated that TALENs are able to induce mutations in F0 Xenopus embryos, but none has demonstrated germline transmission of such mutations in X. laevis. In this report we used the oocyte host-transfer method to generate mutations in both tyrosinase homeologs and found highly-penetrant germline mutations; in contrast, embryonic injections yielded few germline mutations. We also compared the distribution of mutations in several F0 somatic tissues and germ cells and found that the majority of mutations in each tissue were different. These results establish that X. laevis J strain animals are very useful for generating germline mutations and that the oocyte host-transfer method is an efficient technique for generating mutations in both homeologs.
    Description: This work was supported by grants from the NIH (OD010997 and HD084409).
    Keywords: Xenopus laevis ; TALENs ; J strain ; Tyrosinase ; Oocyte host-transfer ; Genome editing
    Repository Name: Woods Hole Open Access Server
    Type: Article
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  • 5
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    Luteinizing Hormone is an effective replacement for hCG to induce ovulation in Xenopus (2017)
    Elsevier
    Details
    Publication Date: 2022-05-25
    Description: © The Author(s), 2016. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Developmental Biology 426 (2017): 442–448, doi:10.1016/j.ydbio.2016.05.028.
    Description: Injection of human Chorionic Gonadotropin (hCG) directly into the dorsal lymph sac of Xenopus is a commonly used protocol for induction of ovulation, but recent shortages in the stocks of commercially available hCG as well as lack of a well tested alternative have resulted in frustrating experimental delays in laboratories that predominantly use Xenopus in their research. Mammalian Luteinizing Hormones (LH) share structural similarity, functional equivalency, and bind the same receptor as hCG; this suggests that LH may serve as a good alternative to hCG for promoting ovulation in Xenopus. LH has been found to induce maturation of Xenopus oocytes in vitro, but whether it can be used to induce ovulation in vivo has not been examined. Here we compared the ability of four mammalian LH proteins, bovine (bLH), human (hLH), ovine (oLH), porcine (pLH), to induce ovulation in Xenopus when injected into the dorsal lymph sac of sexually mature females. We find that both ovine and human LH, but not bovine or porcine, are good substitutes for hCG for induction of ovulation in WT and J strain Xenopus laevis and Xenopus tropicalis.
    Description: This work was supported by a grant from the NIHP40OD010997.
    Keywords: Xenopus laevis ; J strain ; Luteinizing Hormone ; Ovulation ; Chorionic gonadotropin
    Repository Name: Woods Hole Open Access Server
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  • 6
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    Expanding the genetic toolkit in Xenopus : approaches and opportunities for human disease modeling (2017)
    Elsevier
    Details
    Publication Date: 2022-05-25
    Description: © The Author(s), 2016. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Developmental Biology 426 (2017): 325-335, doi:10.1016/j.ydbio.2016.04.009.
    Description: The amphibian model Xenopus, has been used extensively over the past century to study multiple aspects of cell and developmental biology. Xenopus offers advantages of a non-mammalian system, including high fecundity, external development, and simple housing requirements, with additional advantages of large embryos, highly conserved developmental processes, and close evolutionary relationship to higher vertebrates. There are two main species of Xenopus used in biomedical research, Xenopus laevis and Xenopus tropicalis; the common perception is that both species are excellent models for embryological and cell biological studies, but only Xenopus tropicalis is useful as a genetic model. The recent completion of the Xenopus laevis genome sequence combined with implementation of genome editing tools, such as TALENs (transcription activator-like effector nucleases) and CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR associated nucleases), greatly facilitates the use of both Xenopus laevis and Xenopus tropicalis for understanding gene function in development and disease. In this paper, we review recent advances made in Xenopus laevis and Xenopus tropicalis with TALENs and CRISPR-Cas and discuss the various approaches that have been used to generate knockout and knock-in animals in both species. These advances show that both Xenopus species are useful for genetic approaches and in particular counters the notion that Xenopus laevis is not amenable to genetic manipulations.
    Description: This work was supported by the National Institutes of Health (P40 OD010997 to M.E.H., R01 HD084409 to M.E.H., R01 HL112618 to P.T. and F.C., and R01 HL127640 to P.T. and F.C.; and the U.S. Environmental Protection Agency (G11E10367 to D.F.).
    Keywords: CRISPR-Cas ; TALENs ; J strain ; Xenopus laevis ; Xenopus tropicalis ; Knock-in ; Human disease model
    Repository Name: Woods Hole Open Access Server
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  • 7
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    The KnowRISK project: Tools and strategies to reduce non-structural damage (2017)
    EGU
    Details
    Publication Date: 2021-11-29
    Description: The project KnowRISK (Know your city, Reduce seISmic risK through non-structural elements) is financed by the European Commission to develop prevention measures that may reduce non-structural damage in urban areas. Pilot areas of the project are within the three European participating countries, namely Portugal, Iceland and Italy. Non-structural components of a building include all those components that are not part of the structural system, more specifically the architectural, mechanical, electrical, and plumbing systems, as well as furniture, fixtures, equipment, and contents. Windows, partitions, granite veneer, piping, ceilings, air conditioning ducts and equipment, elevators, computer and hospital equipment, file cabinets, and retail merchandise are all examples of nonstructural components that are vulnerable to earthquake damage. We will use the experience gained during past earthquakes, which struck in particular Iceland, Italy and Portugal (Azores). Securing the non-structural elements improves the safety during an earthquake and saves lives. This paper aims at identifying non-structural seismic protection measures in the pilot areas and to develop a portfolio of good practices for the most common and serious non-structural vulnerabilities. This systematic identification and the portfolio will be achieved through a “crossknowledge” strategy based on previous researches, evidence of non-structural damage in past earthquakes. Shake table tests of a group of non-structural elements will be performed. These tests will be filmed and, jointly with portfolio, will serve as didactic supporting tools to be used in workshops with building construction stakeholders and in risk communication activities. A Practical Guide for non-structural risk reduction will be specifically prepared for citizens on the basis of the outputs of the project, taking into account the local culture and needs of each participating country
    Description: Published
    Description: Vienna
    Description: 3T. Pericolosità sismica e contributo alla definizione del rischio
    Description: restricted
    Keywords: damage ; non-structural elements ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: Poster session
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  • 8
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    Xenopus resources: Transgenic, inbred and mutant animals, training opportunities, and web-based support. (2019)
    Frontiers Media
    Details
    Publication Date: 2022-05-26
    Description: © The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Horb, M., Wlizia, M., Abu-Daya, A., McNamara, S., Gajdasik, D., Igawa, T., Suzuki, A., Ogino, H., Noble, A., Centre de Ressource Biologique Xenope team in France, Robert, J., James-Zorn, C., Guille, M., Nicolas, M., Lafond, T., Boujard, D., Audic, Y., Guillet, B. Xenopus resources: Transgenic, inbred and mutant animals, training opportunities, and web-based support. Frontiers in Physiology, 10, (2019):387, doi:10.3389/fphys.2019.00387.
    Description: Two species of the clawed frog family, Xenopus laevis and X. tropicalis, are widely used as tools to investigate both normal and disease-state biochemistry, genetics, cell biology, and developmental biology. To support both frog specialist and non-specialist scientists needing access to these models for their research, a number of centralized resources exist around the world. These include centers that hold live and frozen stocks of transgenic, inbred and mutant animals and centers that hold molecular resources. This infrastructure is supported by a model organism database. Here, we describe much of this infrastructure and encourage the community to make the best use of it and to guide the resource centers in developing new lines and libraries.
    Description: The European Xenopus Resource Centre was funded by the Wellcome Trust (212942/Z/18/Z) and BBSRC (BB/R014841/1). The National Xenopus Resource was funded by the NIH (ORIP/NICHD) (Grant P40 OD010997). Major funding for Xenbase was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (Grant P41 HD064556). XLRRI was funded by the NIH/NIAID (R24-AI-059830 and R21AI139718). CRBX was funded by GIS-IBISA 2014 and Fondation Maladies Rares 2016. The National BioResource Project (NBRP) for Xenopus tropicalis was funded by Japan Agency for Medical Research and Development (AMED).
    Keywords: Xenopus laevis ; Xenopus tropicalis ; transgenesis ; gene editing ; inbred strains ; ORFeome ; model organism database ; resource centers
    Repository Name: Woods Hole Open Access Server
    Type: Article
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