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  • COVID-19  (378)
  • Cell & Developmental Biology
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  • Limnology
  • MDPI - Multidisciplinary Digital Publishing Institute  (379)
  • 2020-2024  (379)
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  • 2020-2024  (379)
  • 1945-1949
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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Biomedical sensors stand at the forefront of modern medical technologies, serving as indispensable components in diverse instruments and equipment. These sensors unravel the intricacies of biological processes and medical interventions. The recent surge in high-density sensor systems, characterized by arrangements in matrix arrays and other configurations, has ushered in a new era of functional evaluation. This spans electrophysiological activity, the metabolic responses of organs and tissues, and motor control analysis, all enriched with crucial spatial information. Functional mapping, a burgeoning approach in various biomedical techniques such as EEG, EMG, ECG, NIRS, and MEG, is proving to be transformative. Its integration enhances our comprehension of complex biological behaviors, where the precise spatial localization of sensing methodologies becomes paramount. The applications of functional mapping using biomedical sensors extend across multiple fields, including neuroscience, neuromuscular physiology, rehabilitation, and cardiology. Its utility ranges from diagnostic purposes to assessing the effectiveness of therapeutic interventions. The primary objective of this reprint was to collect papers that delineate the forefront of techniques, methods, and applications in the realm of biomedical sensors. Additionally, the focus extends to specific algorithms for data processing, ensuring a robust understanding of functional information intricately associated with spatial localization.
    Keywords: EMG ; EEG ; rehabilitation ; neuromotor ; evaluation ; assessment ; review ; machine learning ; biofeedback ; transfer learning ; random forest classifier ; COVID-19 ; intubation ; tracheoesophageal fistula ; tracheal lesions ; acute respiratory distress syndrome ; modeling ; intensive care unit ; muscle synergies ; whole body FES ; neurological patients ; photodynamic therapy ; fluorescence ; laser ; fluorophores ; enamel ; effective connectivity ; kurtosis ; resting-state connectivity ; stationarity ; sleep monitoring ; pressure bed sensor (PBS) ; unobtrusive measure ; multi-scale analysis ; sleep apnea–hypopnea syndrome (SAHS) ; shift-working ; optically detected magnetic resonance ; quantum magnetometer ; magnetoencephalography ; time domain ; functional near infrared spectroscopy ; diffuse optics ; brain ; hemodynamics ; resting-state brain oscillation ; mental workload ; signal processing ; reliability ; cognitive performance ; Simon task ; emotion detection ; valence ; arousal ; wearable sensors ; regression ; classification ; technology acceptance model ; rehabilitation exoskeletons ; therapists ; neuro-rehabilitation ; multiple linear regression ; Pearson’s correlation ; integrated sensor systems ; hand function ; hand osteoarthritis ; electromyography ; diagnosis ; discriminant analysis ; photoplethysmogram ; microcirculation ; deep learning ; convolutional neural network ; modelling ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 2
    Publication Date: 2024-01-08
    Description: This Special Issue delves into the strides made, challenges encountered, and research imperatives within the realm of Industrie 4.0 from both a scientific and practical standpoint. This publication features the voices of Industrie 4.0 pioneers Henning Kagermann and Wolfgang Wahlster, as well as leaders in research and industrial application of smart manufacturing concepts.
    Keywords: Industrie 4.0 ; intelligent manufacturing ; smart factories ; industrial artificial intelligence ; digital twins ; zero-defect manufacturing ; digital ecosystems ; China Manufacturing 2025 ; Industrial Internet ; Cloud Manufacturing ; digitalization ; small-medium enterprises ; new business models ; data democratization ; fourth industrial revolution ; smart manufacturing ; smart factory ; digital transformation ; industry ; sustainability ; sovereignty ; interoperability ; mass customization ; Industry 4.0 ; skills ; competencies ; bibliometric analysis ; survey ; Hungary ; maturity model ; transformation ; methodology ; Industry 4.0 strategy ; socio-technical system ; business transformation ; industrial implementation ; mergers and acquisitions ; knowledge management ; networking ; process management ; informational change ; scarce data ; machine learning ; information fusion ; development of work ; sociotechnical systems approach ; human-oriented work design ; D-SI ; DCC ; digital signature ; calibration ; servitization ; digital factory transformation ; smart services ; IoT ; AI ; internal services ; remote work ; COVID-19 ; investment ; n/a ; digital twin ; digital manufacturing ; multi-agent systems ; data architecture ; Logistics 4.0 ; digital transformation strategy ; urban planning and city operation ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJC Business strategy ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas
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  • 3
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint entails descriptions of novel issues and challenges for primary mental healthcare regarding both general and vulnerable populations on a global scale. It is intended for health professionals and all who are interested in mental health care at the primary level.
    Keywords: depression ; sense of coherence ; burnout ; COVID-19 ; nurses ; medication adherence ; mental health nurses ; tacit knowledge ; schizophrenia ; sensory processing sensitivity ; environmental sensitivity ; university students ; nursing ; scale ; somatization ; number of diseases ; coping strategies ; sex ; aggression ; alexithymia ; comprehensibility ; quality of life ; family caregivers ; students ; medical ; psychological problem ; undergraduate ; Saudi Arabia ; n/a ; prospect theory ; applied psychology ; health ; decision making ; behavior ; prevention ; multiple sclerosis ; Beck depression inventory ; anxiety ; fatigue ; mediation ; lawyers ; suicidal ideation ; occupational stress ; loneliness ; perceived stress ; mental health ; work overcommitment ; mental health care ; adolescence ; internalizing/externalizing problems ; social skills ; neurodevelopmental disorders ; filmmaking intervention ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBP Health systems & services::MBPK Mental health services
    Language: English
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The aim of this Special Issue is to specify relevant principles of mathematics and mechanics in order to explore and understand biological problems. We summarize the most important parameters that influence human performance and that are related to the health sciences for all age groups, throughout their lives. We present papers that aim to introduce the latest research in the fields of health, quality-of-life improvement, and sport rehabilitation and that summarize their recommendations for best practice. The aim for this Special Issue is, therefore, to effectively combine and coordinate research and results in order to understand and improve human movement in medicine, sports, and at work.
    Keywords: tendinopathy ; Achilles tendon ; hyaluronic acid ; viscoelastic properties ; isometric contraction ; matrix metalloproteinase 3 ; interleukin-1beta ; fascia ; chronic low back pain ; myofascial release ; quality of life ; older adults ; oldest-old ; measurement invariance ; SHARE European Survey ; therapeutic exercises ; chronic neck pain ; scapular dyskinesia ; DOMS ; vibration ; post-exercise muscle damage ; physical exercise ; recovery ; women’s rugby ; anthropometry ; body composition ; adiposity ; somatotype ; lower-body strength ; accelerometry ; falls ; squat jump ; syndesmosis ; anterior inferior tibiofibular ligament ; high ankle sprain ; rotational instability ; posterior malleolus ; stabilization ; anatomic repair ; syndesmotic screw ; suture-button ; internal bracing ; treatment algorithm ; cardiac rehabilitation ; peripheral artery disease ; COVID-19 ; intermittent claudication ; review ; pressotherapy ; compression ; regeneration ; return-to-play ; rotator cuff repair ; shoulder injuries ; shoulder surgery ; shoulder assessment ; chronic obstructive pulmonary disease ; COPD ; acupuncture ; acupuncture therapy ; acupuncture treatment ; health-related quality of life ; anterior knee laxity ; stiffness ; general joint laxity ; genu recurvatum ; low back pain ; physical activity ; trunk alignment ; rasterstereographic system ; young males ; tissue flossing ; floss band ; vascular occlusion ; muscle strength ; muscle endurance ; warm-up ; TECAR therapy ; high-intensity laser therapy ; manual therapy ; muscle disorders ; hemophilia ; knee ; virtual reality exposure therapy ; joint pain ; physiotherapy ; daily physical function ; middle-aged and older adults ; CHARLS ; aging ; appendicular muscle mass ; inflammaging ; biomarkers ; adiponectin ; sarcopenia ; bic Book Industry Communication::M Medicine
    Language: English
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The 3D analysis of human movement aims to objectively and quantitatively assess motor functions and alterations. It is a valuable method for sport scientists, coaches, and clinicians to evaluate sport performance, common movements, and alterations. The feasibility of 3D analysis is increasing because it can be adopted both in a laboratory setting or directly in the field, in static or dynamic conditions, and for physiological or pathological movements. This evaluation technique can be adopted for many people, including children, adolescents, adults, and older people, whether they are sedentary or athletes and whether they are healthy or motor-impaired people.
    Keywords: virtual reality ; augmented reality ; lifelogging ; mirror world ; health ; posture training ; feedback ; COVID-19 ; neck-shoulder-region ; shoulder protraction ; upper crossed syndrome ; posture weakness ; physical inactivity ; sedentary behavior ; soccer ; climbing ; exhaustion ; fatigue ; training ; machine learning ; sports ; gender ; data mining ; artificial intelligence ; posture ; reproducibility ; mobile app ; movement ; kinesiology ; sport performance ; inertial sensor ; inertial sensor device ; inertial measurement unit ; training load ; external load ; physical demand ; handstand ; postural control ; postural balance ; sEMG ; stabilometric assessment ; exercise ; Nordic walking ; walking ; 3D kinematics ; biomechanics ; gait analysis ; kyphosis ; spinal mouse ; photogrammetry ; postural evaluation ; bicycle ; cyclists ; saddle pressure ; perineal pressure ; urogenital system ; injury prevention ; cervical ROM ; elastic taping ; neck pain ; musculoskeletal health ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 6
    Publication Date: 2024-01-08
    Description: This reprint, entitled “Management of Acute and Chronic Complications of Lysosomal Storage Diseases in Children and Adults: Current Practice and Future Opportunities”, covers broad aspects of this group of rare diseases. The first theme includes articles on the management of pain, corneal clouding, gastrointestinal and airway diseases in Mucopolysaccharidoses and Mucolipidoses, and the evaluation of dysphonia in Pompe disease. Additionally, attention deficit and ADHD and the management of atherosclerosis in Fabry disease are considered here. The second theme includes diagnostic conundrums in lysosomal storage diseases, e.g., the prenatal diagnosis of Gaucher disease during pregnancy, the diagnosis of secondary hyperparathyroidism in Mucolipidoses, and the application of the new biomarker “plasma neurofilament light” in Niemann Pick C disease, as well as the correlation of enzyme activity with molecular diagnosis in Pompe disease. The articles in the third theme describe the impact of therapies on clinical outcomes. For example, a systematic review of the impact of enzyme replacement therapy on late-onset Pompe disease and trehalose use on Niemann Pick A and B is included. The remaining articles describe the NHS processes for overcoming challenges resulting from the COVID-19 pandemic and the differences in the transition from paediatric to adult services between different countries.
    Keywords: Mucopolysaccharidosis ; corneal clouding ; penetrating keratoplasty ; deep anterior lamellar keratoplasty ; mucopolysaccharidoses ; airway ; obstruction ; management ; Fabry disease ; attention ; Attention Deficit/Hyperactivity ; cognition ; late-onset Pompe disease ; gastrointestinal ; smooth muscles ; PROMIS–GI symptom scales ; GAAKO mice ; glycogen storage disorder ; translational research ; patient-reported outcomes measures ; mucopolysaccharidosis ; MPS ; disease manifestations ; symptoms ; morbidity ; spine disease ; anaesthesia ; perioperative complications ; surgery ; pompe disease ; speech ; voice ; dysphonia ; acoustic ; auditory-perceptual ; GRBAS ; respiratory ; Pompe disease ; gene panel sequencing ; alpha-glucosidase ; GAA ; dried-blood spots ; fabry disease ; neuropathic pain ; depression ; Fabry ; atherosclerosis ; ischaemia ; perfusion ; angina ; Sanfilippo syndrome ; mortality ; Niemann–Pick C ; neurofilament light ; biomarkers ; neurological disease ; glycogen storage disease type II ; enzyme replacement therapy ; COVID-19 ; inherited metabolic disorders ; rare autoinflammatory diseases ; health care providers ; Gaucher disease ; NIHF ; perinatal-lethal Gaucher disease ; PLGD ; ichthyosis ; GBA gene ; airway management ; radiology ; hyoid bone ; chin ; intubation ; intratracheal ; lysosomal storage disease (LSD) ; Niemann–Pick type A ; Niemann–Pick type B ; acid sphingomyelinase ; sphingolipid deposition ; trehalose ; mucolipidosis type II ; ML II ; I-cell disease ; hyperparathyroidism ; mucolipidosis ; ML ; MLII ; transition service ; adult metabolic medicine ; collaboration ; challenges ; inherited metabolic diseases ; healthcare systems ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Partial differential equations are indispensable for modeling various phenomena and processes, such as those in physics, biology, finance, and engineering. Finding solutions to partial differential equations using qualitative theories or quantitative methods, as well as the application of such investigations to real-world problems, has drawn a large amount of interest from researchers. This reprint encompasses all the articles that were accepted and published in this Special Issue titled "Applications of Partial Differential Equations ". We hope that these accepted and published papers will be impactful and motivate future research on partial differential equations for solving complex problems in various fields, disciplines, and applications.
    Keywords: non-linear optimal control ; stratified fluids ; energy functional ; optimal condition ; state variable ; travelling waves ; Eyring–Powell ; geometric perturbation ; nonlinear reaction–diffusion ; unsteady flow ; C∞-semigroups ; analytic semigroups ; Fourier multipliers ; Λ-ellipticity ; fractional Zakharov system ; stochastic Zakharov system ; Riccati–Bernoulli sub-ODE method ; Jacobi elliptic function method ; generalized fractional derivative ; time-diffusion problem ; generalized linear interpolation ; numerical scheme ; backward nonlocal wave equation ; Pascal bases automatically satisfying specified conditions ; integral boundary condition ; nonlocal boundary shape function ; delay differential equations ; 2D parabolic equations ; fractional step method ; convection diffusion problems ; shallow water flow ; Faedo–Galerkin method ; feedback control ; PDE’s stabilization ; tuberculosis ; COVID-19 ; diffusion ; coinfection ; stability ; singularly perturbed problem ; parabolic differential equation ; convection–diffusion problem ; line discontinuous source term ; streamline–diffusion finite element method ; Shishkin mesh ; uniformly convergent ; diffusion equations ; traveling waves ; phototaxis ; bacterial motion ; biological aggregation ; chemotaxis model ; integral inequality ; global uniform boundedness ; CNL-GZE ; lump-type solitons ; rogue wave ; appropriate transformation technique ; optimal decay ; viscoelastic wave equation ; nonlinear time-varying delay ; nonlinear damping ; acoustic boundary conditions ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: The purpose of this Special Issue was to collect and present research results and experiences on energy supply in the Visegrad Group countries. This research considers both macroeconomic and microeconomic aspects. It was important to determine how the V4 countries deal with energy management, how they have undergone or are undergoing energy transformation and in what direction they are heading. The articles concerned aspects of the energy balance in the V4 countries compared to the EU, including the production of renewable energy, as well as changes in its individual sectors (transport and food production). The energy efficiency of low-emission vehicles in public transport and goods deliveries are also discussed, as well as the energy efficiency of farms and energy storage facilities and the impact of the energy sector on the quality of the environment.
    Keywords: energy supplies ; energy security ; energy market ; EU countries ; Hellwig’s method ; sustainability strategies ; sustainable development ; Visegrád Group ; sustainable strategic management ; the renewable energy sector ; energy use ; structures ; food production systems ; Visegrad Group ; energy mix ; renewables ; energy in transport ; energetic efficiency ; energy sources ; economic growth ; developing and developed countries ; energy sector ; environmental quality ; renewable energy sources (RES) ; nuclear energy ; southeastern Poland ; sustainability ; renewable energy sources ; European Union ; cluster analysis ; Visegrad Group countries ; fuels ; cointegration ; Granger causality ; electricity prices ; households ; directions of price changes ; biogas energy ; solar energy ; hybrid biogas plant ; renewable energy ; circular economy ; off-grid systems ; energy efficiency ; social and economic aspects of energy ; economic efficiency ; low emissions ; zero emissions ; e-commerce ; last mile ; parcel lockers ; efficiency of logistics processes ; economies of scale ; simulation of logistics processes ; COVID-19 ; BESS management ; price arbitration ; shift load ; microgrid ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Nearly 18 months later, COVID-19, caused by SARS-CoV-2, continues to present significant challenges to health systems, public health, and the economy of countries across both hemispheres. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed hospitals and clinics in many countries and continue to do so. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This Special Issue collection follows on from the Special Issue “COVID-19: Current Challenges and Future Perspectives” and provides an avenue for authors from various disciplines to provide feedback on the response to and our future global preparedness for COVID-19, as well as to disseminate critical information about SARS-CoV-2 and the associated COVID-19 pandemic.
    Keywords: COVID-19 ; new-onset DM ; severe infection ; mortality ; outbreak ; P.1 variant ; Gamma variant ; SARS-CoV-2 infection ; whole-genome sequencing ; pandemic ; overweight ; obesity ; Peru ; psychological impacts ; public health ; preparedness ; mRNA-1273 ; BNT162b2 ; TAK-919 ; SARS-CoV-2 ; post-vaccination ; healthcare personnel ; vaccination ; asymptomatic infection ; HIV ; infectious disease ; excess mortality ; regdanvimab ; remdesivir ; severe ; community transmission ; population density gradient ; Dhaka ; Bangladesh ; dengue ; undifferentiated febrile illness ; antigen testing ; variants ; reinfections ; breakthrough infections ; vaccine hesitancy ; sub-Saharan Africa ; pulmonary fibrosis ; postacute COVID-19 syndrome ; tuberculosis ; helminth coinfection ; coronavirus ; coordination ; health operations and technical expertise ; AFRO ; diarrhea ; liver ; pancreas ; inflammatory bowel diseases ; liver transplantation ; reproduction rate ; phylogenetic analysis ; clade GK ; D614G ; P681R ; cross-reactivity ; haemorrhage ; thrombocytopenia ; thrombosis ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) ; molecular diagnostics ; real-time polymerase chain reaction (RT-qPCR) ; economy ; income levels ; waves ; policy ; turning points ; occupational exposure ; risk factors ; personal protective equipment ; SIR model ; socio-behavioral aspects ; interaction distance ; school reopening strategy ; self-medication ; over-the-counter ; medicine use ; Pakistan ; clinical features ; Luanda ; Angola ; socioeconomic status ; risk perception ; risk prevention practices ; qualitative ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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  • 10
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Introducing “A Feasible Approach for Natural Products to Treatment of Diseases”–an exploration of the therapeutic potential locked within nature’s abundant offerings. This comprehensive reprint delves into the fascinating realm of natural products, uncovering their inherent properties, mechanisms of action, and potential roles in effective disease management. Through extensive scientific research and reviews, the authors shed light on the immense potential of natural products as a viable approach to enhancing health and combating diseases. This reprint presents a diverse and multidimensional exploration, bridging the gap between traditional wisdom and contemporary scientific understanding and offering new avenues for healthcare professionals, researchers, and enthusiasts to harness the power of nature’s remarkable resources. As a catalyst for unlocking the healing potential of natural products, this reprint inspires further investigation and innovation, and drives us towards a future where their integration into mainstream healthcare becomes indispensable. Discover the possibilities and embark on a health and well-being journey with “A Feasible Approach for Natural Products to Treatment of Diseases”.
    Keywords: cancer immunotherapy ; fructan ; FT-IR ; mass spectrometry ; young green barley ; COVID-19 ; β-glucans ; immunomodulation ; anti-inflammation ; anti-oxidant ; ACE2 regulation ; impedance ; ECIS ; antitumor activity ; anticancer properties ; betulin ; betulinic acid ; Amadori rearrangement compounds ; barley ; anti-obesity ; arginyl-fructose ; adipogenic ; ergosta-5,7,22,24(28)-tetraenol (ERGT) ; cholesta-5,7,22,24-tetraenol (CHT) ; ergosterol biosynthesis ; antimetabolite ; suicide substrate ; Trypanosoma brucei ; coronavirus SARS-CoV-2 ; main protease ; Saussurea costus ; molecular docking ; GC-MS profiling ; Molineria recurvata ; diabetic nephropathy ; urinary biomarkers ; inflammation ; oxidative stress ; walnut ; Juglans regia ; high-fat diet ; insulin resistance ; cognitive function ; JNK/NFκB pathway ; Citri Reticulatae Pericarpium ; flavonoids ; anticancer ; mechanism ; phenotype ; Angelica sinensis polysaccharide ; Astragalus membranaceus polysaccharide ; hexokinase 2 ; glycolysis ; JAK2/STAT3 pathway ; liver regeneration ; Holoptelea integrifolia ; MMP-9 ; wound healing ; friedelin ; oxalactam A ; macrolactam ; anti-Rhizoctonia solani ; Penicillium oxalicum ; molecular dynamics ; non-alcoholic fatty liver disease (NAFLD) ; natural products ; terpenoids ; mechanisms ; treatment ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: In 2020-2022, much of the world was at risk for catching COVID-19. This reprint, “Crimmigration in the Age of COVID-19,” contributes to understanding immigration during the pandemic. It engages a cross-national and interdisciplinary case-study approach to show how countries carved out exceptions to public health protocols for migrants. In the immigration context a variety of governments weaponized public health protocols to criminalize and exclude migrants. The Trump Administration sadistically misplayed the pandemic at almost every turn. Trump came to power on the backs of migrants, referring to them as murderers and rapists. The intersection of Trump’s COVID-19 and migration policies carved out space for the exceptional dehumanization of migrants in 2020-21. This reprint documents the weaponization of public through crimmigration. Crimmigration is the criminalization of migration and migrants via state-of-the-art surveillance and militarized technologies. During the worst of COVID-19, crimmigration strategies--mandatory detention and harsh exclusions— exacerbated the risk of transmission among migrants. Policies not migrants were to blame here. The ostensibly public health related Title42 actually pushed migrants, already at great risk, into unregulated shantytowns controlled by Mexican drug cartels. Additionally, migrants contended with detention facilities, medium security prisons, that functioned as Petrie dishes for the disease. We hope this reprint contributes to understanding the intersection of public health and crimmigration, and border penologies during these exceptional times.
    Keywords: coronavirus ; immigration detention ; migration enforcement ; detention abolition ; detention ; immigration ; human rights ; healthcare ; access to justice ; crimmigration ; deportation ; return ; COVID-19 ; pandemic ; securitisation ; threat prioritisation ; Australia ; New Zealand ; welfare ; exclusion ; surveillance ; attrition ; incarcergration ; decriminalization ; detention standards ; alternatives to detention ; conditions of detention ; COVID ; racial apathy ; white ignorance ; institutional legitimacy ; governing through migration ; The Netherlands ; discourse ; border practices ; asylum seekers ; economic migrants ; Poland ; pushbacks at the border ; COVID-19 pandemic ; governmental xenophobia ; migrants/refugees ; vaccination ; Greece ; n/a ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The purpose of this Special Issue on inclusive research is to capture internationally, “How far have we come?” and “Where do we need to go?” Such questions are relevant now that it has been close to two decades since Walmsley and Johnson (2003) first introduced the inclusive research paradigm in their text, Inclusive research with people with learning disabilities: past, present, and futures. Within this Special Issue we have reprinted 18 articles that promote inclusive research as a paradigm that has succeeded in transferring power to people with intellectual disabilities who were once the "researched" to now being and becoming the "researchers". The articles draw upon the work of co-researchers both with and without the lived experience of disability who have adopted inclusive research as a paradigm to redress the exclusion of people with intellectual disabilities as researchers. All the 18 articles have an eye on the future and are sequenced across the following themes: the individual impact of being and becoming an inclusive researcher; building inclusive research relationships as a duo; being part of an inclusive research network; and using inclusive research to push boundaries and facilitate issues of importance identified by people with disabilities. The reprint concludes with two articles where inclusive researchers of long standing reflect on how to continue to walk forward on the road that aided by this reprint will become more well-travelled?
    Keywords: university ; higher education ; intellectual disability ; inclusive education ; autoethnography ; Down Syndrome ; action research ; design research ; inclusion ; social workers ; intellectual disabilities ; inclusive research ; participatory research ; developmental disability ; mental health ; collaborative groups ; qualitative research ; creative methodologies ; people with intellectual disabilities ; profound intellectual and multiple disabilities ; belonging ; intersubjectivity ; disability studies ; COVID-19 ; lived experience ; disability ; community researchers ; prisoners ; former prisoners ; criminal justice system ; inclusive employment ; collaborative autoethnography ; ethnography ; collaboration ; pandemic ; relationships ; research methods ; health ; rehabilitation ; assistive technology ; consumer-led ; employment ; students with intellectual disability ; sex education ; sexuality and gender identity ; sexual abuse ; inclusive ; research ; learning/intellectual disability ; impact ; life history ; rights ; community ; capacity building ; policy ; and practice ; funding ; co-design ; co-researching ; research with people with intellectual disability ; research with people with learning disability ; advocacy ; self-advocacy ; manifesto for inclusive research ; accessible academic literature ; space and non-accessible space ; down syndrome ; quality of life ; happiness ; n/a ; bic Book Industry Communication::J Society & social sciences::JM Psychology
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  • 13
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Herein we describe some molecular aspects of the recent anti-COVID-19 research, including some approaches making use of natural remedies, especially from medicinal plants, in silico methods, and different experimental procedures that led to the discovery of novel targets of SARS-CoV-2 and consequently novel potential COVID-19 therapeutics. COVID-19 vaccines also find mention in this book with also a description of some adverse effects reported in some cases. Considering that the different beta coronaviruses present certain conserved biomolecular mechanisms and, thus, some common therapeutic targets, finding effective therapies for a specific member of their family (such as SARS-CoV, SARS-CoV-2, and MERS-CoV) even in a scenario of a reduced impact at the time of the related disease on humankind is still relevant as it could offer or inspire efficacious therapeutic strategies not only in the context of novel pathogenic mutations of the already known beta coronaviruses, but also when future zoonoses caused by other beta coronaviruses will emergence, which is not unlikely to occur in the current world where the interactions between humans and wildlife are made more and more frequent due to the growing loss of intact ecosystems worldwide.
    Keywords: coronavirus infections ; pandemics ; natural compounds ; clove ; Syzygium aromaticum ; eugenol ; eugeniin ; SARS-CoV-2 ; COVID-19 ; phytochemicals ; herbal medicine ; catechin ; polyphenol ; tea leaf extract ; theaflavin ; virucidal activity ; MERS-CoV ; S1-NTD ; pharmacophore modeling ; ADME ; quantum mechanical calculation ; DFT ; FMO ; MM/GBSA ; molecular docking ; Molecular Dynamics Simulation ; HOMO ; LUMO ; COVID-19 vaccine ; disseminated intravascular coagulation ; heparin induced thrombocytopenia ; platelet factor 4 ; thrombosis ; thrombotic thrombo-cytopenic purpura ; vaccine induced thrombocytopenia and thrombosis ; disinfectants ; ethanol ; hand hygiene ; ozonated water ; slightly acidic electrolyzed water ; virucidal mechanism ; coronavirus ; renal disease ; nephrotoxicity ; reno-protective effect ; green tea ; epigallocatechin-3-gallate (EGCG) ; flavonoids ; natural products ; medicinal plant ; SARS-Cov-2 nsp10 ; structural similarity ; fingerprint ; ADMET ; toxicity ; main protease ; triazole ; docking ; MD simulation ; drug ; proteomic ; vaccine ; immunology ; biomarker ; cheminformatics ; phytocompounds ; systems pharmacology ; anti-COVID-19 ; drug repositioning ; molecular dynamic simulations ; binding free energy ; signal peptide ; RBD protein ; secretion ; mutant ; nucleocapsid or nucleoprotein ; structure-based drug discovery ; alphafold model and molecular dynamics ; neuroinflammation ; brain fog ; neuropeptides ; neurotransmission ; metabolism ; NSAIDs ; inflammation ; ketoprofen ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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  • 14
    Publication Date: 2023-04-05
    Description: This reprint includes papers from different research fields, reflecting the sectional talks presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, which took place in June 2021. The objective of the 2021 Conference was to bring together perspectives and challenges in doctoral research in a common forum and to provide a platform enabling doctoral researchers to meet and share state-of-the-art developments in their fields. It consists of 16 papers presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, in several fields such as: mechanical and industrial engineering, food science and biotechnology, electrical/electronic engineering, systems engineering and information technologies, chemistry, electrochemistry, and economic models and strategies.
    Keywords: incremental pumps ; profiling of generating tools ; helical surfaces ; Romania ; coastal area ; wind energy ; measurements ; IEC classes ; wind turbines ; mass tourism ; management model ; Constanta ; PESTEL ; Black Sea ; sustainability ; eggplant peels ; bioactive compounds ; hydrogels ; anthocyanins ; beetroot peel ; betalains ; polyphenols ; CCD-RSM ; optimal control ; metaheuristic algorithms ; evolutionary algorithms ; simulation ; ventilation on ships ; HVAC requirements ; COVID-19 ; spread the disease ; airborne transmission ; HEPA filtration ; UV disinfection ; heat recovery ; L-tryptophan ; polypyrrole ; sensor ; amino acid ; cyclic voltammetry ; chronoamperometry ; atorvastatin ; carbon nanotubes ; gold nanoparticles ; Hippophae rhamnoides L. ; carotenoids ; flavonoids ; antioxidant activity ; microencapsulation ; modulation ; electromagnetic disturbances ; electromagnetic compatibility ; military ship ; communication systems ; navigation conditions ; Danube River ; management tool ; quality function deployment ; house of quality ; enwrapping surfaces ; profiling ; geometrical methods ; tower ; wind turbine ; load ; offshore wind ; marine renewable energy ; living labs ; design thinking ; coastal zone ; integrated coastal zone management (ICZM) ; Romanian coastal zone ; Black Sea basin ; wind parameters ; historical data ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCM Development economics & emerging economies
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-05-11
    Description: This reprint emphasizes the perspectives and challenges surrounding COVID-19 and obesity-related cancers, including but not limited to the risk factors of severe COVID-19 in cancer patients; the complications of COVID-19 in cancer patients; the challenges in cancer treatment and surgery; guidelines for cancer care during COVID-19; delayed diagnosis and suboptimal cancer management; the impact of COVID-19 on cancer screening, early diagnosis and cancer presentation; immune response after SARS-CoV-2 infection and vaccination in cancer patients; psychological distress among cancer survivors; telehealth in cancer care; the role of diet and nutraceuticals in the prevention of severe COVID-19 and cancer; and the effects of COVID-19 pandemic on cancer research.
    Keywords: COVID-19 ; neutropenia ; G-CSF treatment ; respiratory failure ; colorectal neoplasms ; gastrointestinal neoplasms ; immune checkpoint inhibitors ; neoplasms ; oncogenic viruses ; oncolytic virotherapy ; post-acute COVID-19 syndrome ; reactive oxygen species ; tumor escape ; SARS-CoV-2 ; thyroid cancer ; differentiated thyroid cancer ; COVID-19 severity ; inflammation ; immunity ; oxidative stress ; obesity ; SARS-Cov-2 ; oncology ; cancer screening ; clinical trials ; melanoma ; management ; pandemic ; teledermatology ; diagnostic delay ; immunotherapy ; vaccination ; lymph adenopathy ; cancer ; nutraceuticals ; supplements ; colorectal ; meta-analysis ; gynecologic oncology ; malignancy ; blood cancer ; hematologic malignancy ; leukemia ; lymphoma ; multiple myeloma ; myelodysplasia ; breast cancer ; cancer care ; screening ; surgery ; psychological distress ; cancer therapies ; immunogenicity ; safety ; vaccine hesitancy ; tumor subtype ; mortality ; intensive care unit ; medico-administrative data ; France ; n/a ; bic Book Industry Communication::M Medicine
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  • 16
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: Ageing is a diverse and multifaceted experience that is unique to each person. The process of ageing is lived differently according to each individual’s socio-cultural, historical, religious, and political context, among other factors. However, the stereotype of homogeneity is still one of the strongest aspects related to later life. This Special Issue covers manuscripts of original research that critically explore the experience of old age and the process of growing older from the social sciences and humanities perspectives. It also explores the topics pertaining to social gerontology, cultural and literary gerontology, environmental gerontology, gerotechnological studies, social anthropology, gender studies, body politics, sexuality, active and healthy ageing, space and place, age-friendly politics and other themes. The published articles collect arguments that show the variables and uniqueness of later life, and expand on the current theoretical frameworks in the field of age studies and beyond. The overall aim of this Special Issue was to broaden the gerontological scholarship and develop critical thought of old age and the life course beyond the merely biological processes of growing older and their sociocultural constructs. This Special Issue can be of interest to scholars, practitioners, stakeholders, care workers and individuals who are concerned with the dynamics of ageing as well as current and future dialogues on the unique experiences of ageing.
    Keywords: ageing ; older adults ; intimacy ; creativity ; strict morality ; sexuality ; theories of retirement ; rhythmanalysis ; management of time ; interdisciplinary gerontology ; busy ethic ; societal rhythms ; home ; identity ; Ireland ; place attachment ; rural ; Sweden ; women ; inclusivity ; Zimbabwe ; urban environments ; discourse analysis ; urban policy ; Africa ; ageism ; COVID-19 ; fourth age ; nursing homes ; third age ; cultural and literary gerontology ; aging and society ; agism ; popular culture and comics ; DC superheroes ; aging in place ; dementia ; cognitive changes ; design practice ; user involvement ; participatory design ; socio-gerontechnology ; active ageing ; age-friendly ; age panic ; metaphor ; neoliberal imagination ; older adults’ media practices ; older adults’ media biographies ; long-term care ; social isolation in later life ; social agency ; person-centered care ; information and communication technology (ICT) ; life course perspective ; communicative ecology mapping ; focused ethnography ; activism ; Iaioflautas ; intergenerational solidarity ; politicization ; social movements ; culture ; interdependence ; older immigrants ; religious minority ; social relationships ; older people ; public participation ; European welfare states ; gerontological responses ; pandemic management ; materiality ; corporeality ; humanoid robot Pepper ; human–robot interactions ; gender ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-05-11
    Description: There has been a rapid development in the academic literature over the last ten years on papers relating to individualization, personalization, patient-, client-, consumer- and person-centredness, with work on conceptual, instrumental, observational, and experimental levels. This Special Issue presents papers that can further establish the current state of science on these topics relating to personalized nursing and health care. We collected papers that highlight and further the knowledge base conceptually, instrumentally, observationally, and experimentally with sound theoretical and methodological underpinnings and implications for research, theory, and clinical work in the disciplines of nursing, medicine, allied health, and beyond.
    Keywords: anxiety ; life satisfaction ; life–work concerns ; melatonin ; cortisol ; biopsychosocial model ; obstetric complications ; patients’ rights ; student ; nursing ; personalized medicine ; HIV ; mobile health ; smartphone application ; symptom management ; nurse practitioners ; nursing home ; COVID-19 ; palliative care ; end-of-life ; dignified death ; older adults ; accidental falls ; fall prevention ; barriers ; patient compliance ; music therapy ; dementia ; caregiver ; RCT ; patient-centred care ; competence ; assessment ; instrument ; measurement ; validity ; reliability ; individual care ; nurses ; older diabetes patients ; physicians ; support ; Parkinson’s disease ; nursing training ; integrated care ; Parkinson nurse ; personalized care ; multidisciplinary care ; patient-centered ; arthritis ; autoimmune disease ; sociopsychological factors ; emotion ; depression ; self-identity ; qualitative study ; observational study ; dysmenorrhea ; kinesio tape ; auricular acupressure ; pain ; nursing care ; patient care planning ; quality of health care ; conditional inference trees ; education ; distance ; learning ; digital ; drawings ; Nigeria ; perinatal loss ; social networks ; stillbirth ; stillborn ; functional status ; health care ; hospitalization ; activities of daily living ; pelvic floor muscle exercises ; pelvic floor dysfunction ; qualitative research ; therapeutic exercise ; therapeutic adherence ; women’s health physiotherapy ; diabetes mellitus type 2 ; prediction model ; LogicRegression ; interpretability ; pelvic organ prolapse ; lifestyle changes ; women’s experience ; n/a ; foot ; foot self-care ; methodological review ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: After almost two decades of continuous development in bio, circular, and green economy, the time is ripe for the assessment of the major achievements and challenges that private and public enterprises face today to further enhance these global sustainability concepts. Due to the central role of political incentives for the development and implementation of environmentally friendly and sustainable practices, the present book project focuses on the nexus between public policies, institutions, quality of public sector management, and patterns of interaction between government and private businesses in backing bio, green, and circular economy practices and eco-innovation. In addition, the project also accommodates surveys that elaborate on the differences between the implementation of new organizational forms and scientific innovations in technologically advanced and developing settings.
    Keywords: energy demand ; renewable energy ; biomass ; energy policies ; organizational factors ; healthcare waste management practices ; public hospitals ; Libya ; consumers ; cluster analysis ; sustainable consumption ; mass media ; social media ; green hydrogen ; green hydrogen value chain ; developing countries ; renewable energy sources ; hydrogen strategy ; scaling ; upscaling ; scaling innovation ; innovation diffusion ; innovation ; systematic literature review ; garbage sorting ; urban garbage disposal ; rural garbage disposal ; willingness ; family life ; neighbourhood ; COVID-19 ; Pakistan economy ; economic scale ; Keynesian theory ; mitigation ; economic revival measures ; innovations ; renewable power ; rebound effect ; low-carbon economy ; carbon pricing policy ; border carbon tax ; Sino–US trade friction ; export grab effect ; firm innovation ; GDP prediction ; feature selection ; deep learning ; temporal convolutional network ; organizational sustainability ; social and economic sustainability ; knowledge sharing ; organizational agility ; organizational behavior ; sustainable organizations ; economic sustainability ; consumer experience ; sustainable commerce ; online consumer behaviour ; e-commerce platform ; online purchase intention ; online customer engagement ; energy security ; energy policy ; energy resources ; sustainability ; bibliometrics ; circular business model ; open business model ; sharing economy ; circular economy ; peer-to-peer ; electricity trading ; green product ; green consumer behavior ; environmental responsibility ; environmental concern ; green purchasing decisions ; green business ; consumption dimension ; production dimension ; financial dimension ; technological dimension ; fundraising campaigns ; social networking sites ; NPO ; humanitarian response ; Kuwait ; Bahrain ; Guatemala ; forest ; property rights ; community concession ; entrepreneurship ; forest sustainability ; economic development ; free-market environmentalism ; Latin America ; consumption coupons ; purchase probability ; inventory optimization ; minimum-cost maximum-flow ; bioeconomy ; green growth ; eco-innovation ; environmental Kuznets curve ; EKC ; environmental economics and policy ; ecological economics ; resource management ; sustainable development ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: The reprint provides the most relevant and state-of-the-art in the field, including recent developments in the production of natural compounds from various bioresources, and their formulations as bioactives. This reprint also covered the engineered approaches for enhanced biological properties and their potential applications. Identification of novel compounds and bioprocess tools to improve the quantity and quality of bioactive compounds and their formulations are exclusively covered in this reprint.
    Keywords: anti-solvent ; enzymatic saccharification ; EMIM-Ac ; ethanol ; ionic liquid ; lignocellulosic biomass ; recycling ; agro-industry ; microencapsulation ; bioactive compounds ; in vitro digestion ; yogurt ; cannabis ; cannabinoids ; postharvest ; drying ; curing ; storage ; biosynthesis ; pre-treatments ; sorption isotherm ; Raphanus sativus L. ; recombinant IFN-α2a ; apoptosis ; antiviral and antitumor activity ; Japanese knotweed rhizome bark ; SARS-CoV-2 ; COVID-19 ; virus neutralization test ; nano-formulation ; nutraceuticals ; prebiotics ; nanofabricated delivery system ; liposomes ; nano-emulsions ; Abelmoschus manihot ; neurodegenerative disease ; oxidative stress ; proliferation ; inflammation ; nucleotide excision repair ; Actinosynnema pretiosum ; ansamitocin P-3 ; ssgA ; AdpA ; morphological differentiation ; pomegranate ; pomace ; extraction ; biological activity ; functional beverages ; sensory quality ; vitamins ; formulation ; homogeneous systems ; hydrophile–lipophile balance ; Emblica officinalis ; phytochemicals ; hyperlipidemia ; pharmacology ; nanoformulation ; Prunus mume ; vasorelaxant ; hypertension ; angiotensin receptor blockers ; agro-waste ; valorization ; value-added bioproducts ; micro/nano encapsulation ; agri-food-pharma applications ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-06-23
    Description: The field of healthcare is constantly evolving and advancing with new technologies and innovations. Among these, assistive technologies, robotics, and automated machines are rapidly gaining ground as powerful tools to improve the quality of care and enhance patient outcomes. From wearable devices that monitor vital signs to surgical robots that assist in complex procedures, these technologies have the potential to revolutionize the way we deliver healthcare. The development and the integration of assistive technologies, care robots, and automated machines are strategic both as single components, when paired together, and when interconnected in the health domain.This reprint explores the latest developments in assistive technologies, robotics, and automated machines in the health domain, providing a comprehensive overview of their applications and potential impact. The reprint is for the benefit of healthcare professionals, researchers, engineers, and students interested in these rapidly evolving fields.
    Keywords: n/a ; rehabilitation ; virtual reality ; upper extremity ; virtual rehabilitation ; Facebook advertisements ; personalized advertisements ; social media ; precision medicine ; public health informatics ; public health communications ; consumer health informatics ; population health ; human immunodeficiency virus ; diagnosis ; acquired immunodeficiency syndrome ; regulation ; artificial intelligence ; digital radiology ; medical devices ; child patient ; care robot ; caregiver ; hospitalization ; testing ; motor coordination ; screening tool ; robotic exoskeletons ; servo motor ; brushless ; brushed ; actuators ; torque ; centre mass ; clinical decision ; U-Net ; CNN ; CAD system ; brain tumor ; classification ; segmentation ; humanoid social robot ; older adults ; living alone ; loneliness ; social isolation ; home-based ; spinal cord injuries ; assistive technology ; tongue barbell piercing ; tongue drive system ; inductive tongue control system ; rehabilitation robot ; assistive technology sports rehabilitation ; continuation therapy ; degenerative diseases ; elder ; telemedicine ; expectation confirmation theory ; trust typology theory ; personal privacy concerns ; urination and defecation care ; automation ; multi-sensor fusion detection algorithm ; stroke ; gait robot ; goal setting ; Remote Monitoring Digital Solutions (RMDSs) ; elderly patient ; mental and emotional decline ; COVID-19 ; exoskeleton device ; gait ; robot ; personal satisfaction ; physical fitness ; orthodontics ; AI ; ChatGPT ; AI Treatment Assessment ; Teledentistry Cephalometrics ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBG Medical equipment & techniques
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: This reprint covers 27 papers published in the Special Issue entitled “Corporate Finance, Governance, and Social Responsibility,” which examines several topics related to corporate finance, financial modeling, corporate governance, and corporate social responsibility. Corporate finance-related articles (Anton and Afloarei Nucu, 2021; Bae et al., 2023; Kedzior et al., 2020; Lääts and Lukason, 2022; Miglo, 2020; Mihail et al., 2021; Mota and Moreira, 2023; Tsolas, 2021; Tudose et al., 2021; and Wen et al., 2021) focus on the drivers of the capital structure and firm performance, the effect of working capital management on profitability, and the link between derivative use and profitability. Regarding financial modeling, stock market volatility was explored during COVID-19 (Gherghina et al., 2021). Corporate governance studies (Aluchna and Kuszewski, 2020; Ararat et al., 2021; Ding and Chea, 2021; Kjærland et al., 2020; Lourenço et al., 2021; Lukason and Camacho-Miñano, 2020; Maier and Yurtoglu, 2022; Mihail and Dumitrescu, 2021; Mihail et al., 2022; Mihail and Micu, 2021; and Pourmansouri et al., 2022) examine the effect of corporate governance compliance practices, board attributes, or employee stock option plans on bankruptcy risk, performance, firm value, or earnings management. Regarding CSR (Bozos et al., 2022; Rossi et al., 2021; Saeed and Sroufe, 2021; Singh and Hong, 2023; and Tseng and Shih, 2022), the research focuses on how CSR affects financial performance, risk management, or analyst profits estimates.
    Keywords: capital structure ; New Technology-Based Firms (NTBFs) ; internal and external innovativeness ; intangibility ; corporate governance ; information disclosure ; timeliness of financial reporting ; law violation ; private firms ; corporate governance best practice ; corporate governance compliance ; company value ; Warsaw Stock Exchange ; accrual earnings management ; Nordic model ; zero-debt policy ; flexibility ; tax shield ; free cash flow problem ; debt overhang ; dividend policy ; emerging economy ; profitability ; working capital management ; employee stock option plans ; executive compensation ; firm performance ; New Zealand ; financial derivatives ; Shenzhen stock exchange of China ; state-owned companies ; private-owned enterprises ; performance ; measurement of performance ; EVA ; strategies ; business success ; Romanian stock market ; volatility clustering ; autocorrelation ; COVID-19 ; GARCH models ; vector autoregression model ; Granger causality ; CSR practice ; financial performance ; environmental social and governance (ESG) ; board size ; independent board members ; return on equity ; Romania ; boards of directors ; Egypt ; gender diversity ; Egyptian Revolution ; investor relations ; Bucharest Stock Exchange ; firm efficiency ; data envelopment analysis (DEA) ; pharmaceutical, cosmetic and detergent (PCD) firms ; Greece ; agency ; corporate social responsibility ; information environment ; distress risk ; trade credit ; LGBT ; market value ; resource-based theory ; sexual orientation and identity ; simultaneous equations ; protection of minority investors ; stock market development ; economic growth ; board diversity ; CEO characteristics ; board committees ; ownership concentration ; agency theory ; COVID-19 pandemic ; Iran ; global economy ; financial management ; corporate social responsibility reports ; mandatory disclosure ; mandatory assurance ; analyst forecast accuracy ; analyst forecast dispersion ; board independence ; bankruptcy risk ; Europe ; corporate sustainability ; environmental ; social ; failure risk ; nonbinding voting ; shareholder activism ; systematic risk ; risk management practices ; performance outcome ; strategy ; supply chain ; capital budgeting ; capital budgeting practices ; footwear industry ; metalworking industry ; manufacturing ; SMEs ; equity investments ; property and liability insurers ; financial crisis ; n/a ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCM Development economics and emerging economies
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: The use of telemedicine and mobile devices is growing, and sensors might aid in creating creative solutions. Developing these solutions is crucial for monitoring senior citizens, lifestyles, and medical procedures. This Special Issue’s goal was to bring together academics and professionals in healthcare and medicine interested in using information and communication technologies (ICT) to serve people with special needs. The development of assistive technology for various users to follow sports and other activities is strongly tied to this study area. Data protection is crucial, and the development of these solutions for medical uses should be verified. The security and privacy of the information may be tied to other recognized research projects for their acceptability. ICT research has considerably improved quality of life and has fully assimilated all citizens into society through medical rehabilitation and assistive technology. The technologies and research fields that influence medical informatics include databases, networking, graphical user interfaces, data mining, machine learning, intelligent decision support systems, and specialized programming languages. Because mobile devices are commonly used for several everyday chores and are equipped with sensors that monitor various physical and physiological indicators, it is crucial to encourage the development of m-Health and e-Health solutions for healthcare practitioners. In this area, several solutions are now being developed. In addition, they can collaborate with emerging technologies for social assistance while enhancing life quality.
    Keywords: data privacy ; taxonomy ; IoT ; COVID-19 ; mobile application ; accelerometer sensor ; stand-up time ; total time ; aging ; linear-map convolutional neural network ; direct acyclic graph ; action recognition ; spatial feature ; temporal feature ; frailty ; home monitoring ; user-centered design ; usability ; user experience ; acceptance ; activity recognition ; Internet of Things ; smart house ; deep learning ; channel state information ; glaucoma screening ; retinal images ; segmentation ; classification ; precision nutrition ; food plans ; machine learning ; food logging ; Eight Hop Test ; systematic review ; measurement ; sensors ; diseases ; wrist-wearable device ; PPG processing ; physiological parameters ; web-based applications ; data analysis ; elderly monitoring ; successful aging ; gerontechnology ; AAL ; healthcare ; prevalidation ; deployment ; chronic heart failure ; large-scale pilot ; H2020 ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNT Media, information & communication industries::KNTX Information technology industries ; bic Book Industry Communication::U Computing & information technology::UY Computer science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: We are honored to announce this reprint, containing contributions from the top experts in the field of logic and fuzzy logic. In total, this reprint consists of 10 papers that were selected from more than 20 submissions. The 10 papers comprising the reprint are the product of re-known experts in fuzzy logic from all over the world, such as Canada, Poland, China, Slovakia, Lithuania, Turkey, Pakistan, Germany, Serbia, Portugal, Taiwan, Norway, India, Saudi Arabia, Thailand, and Mexico. We expect that the papers comprising the Special Issue will contribute to an advancement in the state of the art in the fields of logic and also fuzzy logic.
    Keywords: fuzzy-sets ; fuzzy-random variables ; distribution generating function ; fuzzy binomial distribution ; Fuchs distribution ; MADM ; Aczel–Alsina operations ; IVIFNs ; IVIF Aczel–Alsina geometric aggregation operators ; interval type-3 fuzzy theory ; fuzzy control ; manufacturing ; Vietè’s method ; Newton–Raphson method ; regula falsi method ; testing of algorithms ; foundations of mathematics ; arithmetic ; set theory ; spatial fuzzy C-means ; COVID-19 ; rustbelt states ; extrapolation ; interpolation ; proving ; refuting ; improving ; fuzzy set ; linear Diophantine fuzzy sets ; linear Diophantine fuzzy relations ; level cut relations ; rough approximations on two universes ; decision analysis ; multi-valued logic trees ; hydraulic proportional valve ; weighting factors ; optimization ; granular computing ; formal concept analysis ; intuitionistic fuzzy sets ; periodicity ; spatial and temporal aspects ; knowledge discovery ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Novel Anticancer Strategies (Volume II) reviews important findings and updates within the cancer therapy field of great interest to those in academic research studying the development and validation of novel anticancer approaches. The Editor invited preeminent specialists to contribute to original and review articles devoted to key areas of major progress and expectations. Key Features:Nanoparticle-based drug delivery in cancer therapy;Nanoerythrosomes;Cancer immunotherapy;Therapeutic vaccines;Oncogenic and tumor suppressive components of the cell cycle;Antimitotics in cancer clinical trials;Multifunctional enzymes as anti-cancer drug targets;Targeting undruggable proteins and non-coding RNAs;Cell-penetrating peptides;Repurposed cancer drugs in clinical trials;Circulating tumour cells.
    Keywords: Breast cancer treatment ; Photodynamic therapy ; Inorganic nanoparticles ; Active targeting ; cathepsins ; BAX ; MOMP ; ubiquitination ; apoptosis ; chemotherapy ; cancer ; nanoerythrosome ; nanoerythrocyte ; nanovesicles ; biomimetic ; cancer therapy ; diagnostics ; imaging agents ; cell cycle ; cyclin-dependent kinase ; p16 ; p21 ; p27 ; breast cancer ; prognosis ; drug delivery ; HL60 ; leukemia ; prodrug ; resistance ; retinoic acid ; vitamin K ; drug repurposing ; COVID-19 ; pandemic ; vaccination ; multi-drug resistance ; enhanced permeation and retention effect ; nanotherapeutics ; cancer theranostic ; clinical translation ; cell-penetrating peptides ; protein transduction domains ; tumor imaging ; targeted therapies ; dog ; comparative oncology ; molecular targets ; spheroids ; tumoroids ; hydrogel ; collagen ; agarose ; mammary spheroids ; tissue engineering ; cisplatin ; melanoma ; melanin nanoparticles ; cytotoxicity ; laser medical applications ; hyperthermia ; antimitotics ; mitotic slippage ; spindle assembly checkpoint ; clinical trials ; TRAIL ; cancer stem cells ; TRAIL resistance ; angiogenesis ; on-demand drug delivery systems ; electrospun nanofibers ; poly (N-isopropylacrylamide) ; gold nanorods ; paclitaxel ; β-Cyclodextrin ; SPIONs ; metallodrugs ; RAPTA derivatives ; phosphino-amine ligands ; CTCs ; NSCLCs ; metastasis suppression ; curcumin ; flavonoids ; TNBC ; immunotherapy ; immune checkpoint ; nanocarrier ; combinational immunotherapy ; lung cancer ; miRNA ; oncomiRs ; photodynamic therapy PDT ; porphyrin ; iron oxide nanoparticles ; mesoporous silica nanoparticles ; antibody functionalization ; targeted drug delivery systems ; molecular-targeted therapies ; multifunctional enzymes ; HCC ; CHRNA5 ; metastasis ; stemness property ; sorafenib sensitivity ; neoantigens ; vaccine ; Patched ; chemotherapy resistance ; metastases ; persistent cells ; adrenocortical carcinoma ; BUB3 ; mitosis ; senescence ; anticancer target ; boron neutron capture therapy ; 4-borono-l-phenylalanine ; drug discovery ; solubility ; mebendazole ; polymer ; HPMA ; controlled drug release ; PLK1 ; BI2536 ; Navitoclax ; slippage ; PD-1 ; gemcitabine ; new anti-cancer drugs ; precision medicine ; undruggable targets ; non-coding RNAs ; oligonucleotide therapeutics ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-11-30
    Description: This reprint addresses healthcare transformation towards personalized, participative, preventive, predictive, and precision medicine (5P Medicine) with the support of new technologies such as micro-, nano-, and bio-techniques, as well as artificial intelligence and learning systems. It focuses, therefore, on the representation and management of knowledge from different domains and their actors, using their methodologies and languages but also individual skills and experiences. The outcome is a system-oriented, architecture-centric, ontology-based, policy-driven approach allowing a formal representation and management of health ecosystems, including their integration and interoperability. Such development is accompanied by security, privacy, and ethical challenges to be resolved. The reprint describes the principles, methodologies, and standards for successfully managing the transformation of health and social care, illustrated by many practical examples and implemented use cases. The reprint is based on papers published in the context of the pHealth 2021 Conference in Genoa, Italy. However, the content goes far beyond the focus and size of the original papers.
    Keywords: syntactical parsing ; natural language processing ; electronic health records ; Node2Vec ; automatic text labeling ; graph algorithms ; mobile application ; mHealth ; digital technology ; emergency service ; hospital ; emergency department ; clinical laboratory information systems ; communication ; text messaging ; pediatrics ; postoperative risks ; aortic aneurysm ; integrated data ; predictive modeling ; feature extraction ; machine learning ; privacy ; trust ; modelling ; antecedents ; Fuzzy attractiveness rating ; didactic ; Healthcare IT ; citizens ; E-Learning ; digitalization ; digitization ; patient empowerment ; education ; healthcare communications ; surgical biobank ; post-traumatic arthritis ; osteomyelitis ; semantic data integration ; system theory ; biomedical ontologies ; knowledge representation ; ascending aortic dilatation ; aneurysm ; risk factors ; echocardiography ; social media ; physical activity ; chatbot ; health ; participatory health ; usability ; conversational agent ; behavior change ; genomics ; security ; modular architecture ; GIPAMS ; standards ; Markov model ; periprosthetic joint infection ; revision arthroplasty ; total hip replacement ; decision trees ; oncohematology ; epilepsy risk ; epilepsy modeling ; COVID-19 ; pneumonia ; dynamical Bayesian networks ; treatment trajectories ; auto ML ; eHealth ; data democratization ; health data infrastructure ; privacy-enhancing technologies ; hospital-acquired infections ; international coding system ; laboratory information systems ; information extraction ; stress detection ; individual learning ; centralized learning ; federated learning ; smartwatch ; health transformation ; ecosystems ; knowledge representation and management ; architecture ; n/a ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-29
    Description: The reprint showcases a review and empirical studies on life satisfaction and its related aspects. The studies are from several countries on a wide range of samples including university students, faculty, nurses, entrepreneurs, adolescents, national databases, refugees, and community samples.
    Keywords: preference-based health-related quality of life ; refugee ; EQ–5D–5L ; post-migration stressors ; self-efficacy ; recreation specialization ; flow experience ; life satisfaction ; mediating effect ; Gallup World Poll ; New Zealand ; wellbeing ; trust in government ; social security fairness ; social security satisfaction ; social entrepreneur ; exit intention ; prosocial motivation ; gender ; nurses ; quality of life ; protective factors ; coping strategies ; type of practice ; COVID-19 ; ageism ; stereotypes ; discrimination ; work engagement ; conscientiousness ; physical well-being ; subjective well-being ; activities of daily living ; health ; physical activity ; post-COVID-19 condition ; work ; community home-based elderly care ; Chinese older adults ; kindness interventions ; materialism ; satisfaction with life ; self-determination theory ; emotional intelligence ; resilience ; self-esteem ; university students ; happiness ; positive affect ; family functioning ; developmental age ; systematic review ; youth ; adolescence ; normative stressors ; interpersonal stressors ; school stressors ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: This reprint is the result of a Special Issue, which took place in the International Journal of Environmental Research and Public Health (IJERPH) during 2022-2023. The general topic of the reprint discusses the different uses, protection and promotion of food, always from a broad perspective, through 15 innovative research papers, from both qualitative and quantitative methodological approaches.
    Keywords: health ; values and preferences ; red meat ; processed meat ; cross-sectional study ; mixed methods ; explanatory sequential ; survey ; food consumption ; well-being ; dietary patterns ; sustainable consumption ; consumer behaviour ; food well-being ; subjective well-being ; social influence ; food choice ; climate-friendly eating ; social media ; political consumerism ; children’s health ; functional diversity ; commensality ; self-esteem ; shame ; loneliness ; aquaculture ; food heritage ; carp ; consumer preferences of Young Adult Populations ; marketing place ; sustainability ; consumer attitudes ; organic food ; consumer behavior ; sustainable food ; food surveys ; food change ; food policies ; sociology of food ; obesity ; edible insects ; alternative proteins ; planetary health ; systematic review ; gastronomic routes ; Iberian ham ; olive oil ; wine ; Córdoba ; ARIMA ; food ; gastronomic tourism ; social media data ; outdoor dining environment preference ; rural restaurants ; human-oriented ; rural sustainable development ; food label ; consumer purchase intention ; attitude ; food delivery app ; online food delivery ; online-to-offline (O2O) ; COVID-19 ; post-pandemic ; thematic review ; food preferences ; entomophagy ; nutrition surveys ; food neophobia ; cultural domains ; pile sorts ; food risk ; trust ; distrust ; pregnancy ; breastfeeding ; prehabilitation ; ERAS ; endometrial cancer ; surgery ; protein supplementation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-07-14
    Description: Advancements in medical imaging modalities have resulted in increasing the importance and demand of pediatric radiology. This reprint showcases various examples of advanced research in pediatric radiology and nuclear medicine. These include the use of medical imaging modalities such as computed tomography, general radiography, magnetic resonance imaging, positron emission tomography, single-photon emission computed tomography, and ultrasound for diagnosis, as well as the performance of artificial intelligence (AI) in computer-aided detection and diagnosis in the pediatric population. The radiation dose issue of pediatric radiological examinations and emerging AI technology for dose reduction, as well as the use of three-dimensional printing based on medical images for pediatric surgical planning, healthcare professional education, and patient–clinician communication are also covered.
    Keywords: as low as reasonably achievable ; computed tomography ; convolutional neural network ; deep learning ; dose reduction ; generative adversarial network ; image processing ; machine learning ; medical imaging ; noise ; contrast-enhanced ultrasound ; head ultrasound ; brain death ; infants ; ancillary test ; child ; paediatric ; infant ; adolescent ; chest X-ray ; CXR ; chest radiography ; COVID-19 ; SARS-CoV-2 ; coronavirus ; biliary atresia ; ultrasonography ; diagnostic accuracy ; intraoperative cholangiography (IOC) ; diagnostic performance ; elastography ; three-dimensional printing ; congenital heart disease ; children ; model ; personalized medicine ; application ; confusion matrix ; disease identification ; image interpretation ; pneumonia ; artificial intelligence (AI) ; deep learning (DL) ; paediatric pneumonia ; chest radiograph ; computer-aided detection (CAD) ; cumulative ; radiation dose ; acute tonsillitis ; shear wave elastography ; stiffness ; pediatric ; magnetic resonance imaging ; infection ; neck ; emergency medicine ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The 10th International Conference on Modern Circuit and System Technologies on Electronics and Communications (MOCAST 2021) will take place in Thessaloniki, Greece, from July 5th to July 7th, 2021. The MOCAST technical program includes all aspects of circuit and system technologies, from modeling to design, verification, implementation, and application. This Special Issue presents extended versions of top-ranking papers in the conference. The topics of MOCAST include:Analog/RF and mixed signal circuits;Digital circuits and systems design;Nonlinear circuits and systems;Device and circuit modeling;High-performance embedded systems;Systems and applications;Sensors and systems;Machine learning and AI applications;Communication; Network systems;Power management;Imagers, MEMS, medical, and displays;Radiation front ends (nuclear and space application);Education in circuits, systems, and communications.
    Keywords: incremental power and timing optimization ; Lagrangian relaxation ; gate sizing ; multimode multicorner ; physical optimization ; two-qubit states ; quantum computers ; quantum gates ; Rabi oscillations ; single qubit quantum computer ; quantum operations simulation ; vision transformers ; computer vision ; deep learning ; artistic style recognition ; memristor model ; tantalum oxide ; memory crossbar ; nonlinear dopant drift ; window function ; LTSPICE library memristor model ; stochastic computing ; stochastic filtering ; stochastic FIR filter ; unconventional computing ; electrical masking ; interconnection delay ; Single Event Multiple Transients ; Soft Error Rate ; STA ; TCAD ; timing-masking ; transient faults ; IoT ; wireless sensor networks ; hydroponics ; smart agriculture ; Network-on-Chip ; bufferless routing ; 3D NoC ; Markov chains ; visible light communication (VLC) ; wireless communication ; analog front end (AFE) ; pre-amplification ; classification ; COVID-19 ; lightweight neural network ; medical imaging ; chest X-rays ; image sensors ; 3D pixels ; 3D sequential integration ; 3DSI ; monolithic 3D ; M3D ; coupling ; parasitic capacitances ; memristor ; emulator ; analog design ; switched capacitor ; mixed signal ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: The digital economy has significantly impacted countries throughout the world by contributing to the growth of the economy and the further progress of societies. Recent developments demonstrate that the information and innovation-driven era triggered integration of traditional activities and digital technologies. Moreover, the rise of innovation has been accelerating in emerging industries such as cleantech, the new generation of information technology, biotechnology, and high-end equipment manufacturing. The estimations provided by the World Economic Forum predict that “new value creation over the next decade will be based on digitally enabled platform business models”. Therefore, organizations must change the traditional approaches adopted and capture value in the context of digital disruptions. These tendencies raise a number of management challenges that need to be solved by the efforts of the scientific community. Therefore, this Special Issue provides the platform for a fruitful discussion and the development of relevant theories.
    Keywords: leadership behaviors ; e-training ; employment security ; stress management ; employee performance ; teaching staff ; digitalisation ; hospital ; optimisation of resources ; equipment/facilities ; COVID-19 ; benefits ; savings ; leadership styles ; high-involvement human resource management practices ; small and medium enterprises ; digital era ; active learning ; growth mindset ; self-efficacy ; engagement of employees ; adaptive performance ; innovation management ; digital entrepreneurship ; creative industries ; tourism ; creative entrepreneurship ; research agenda ; e-government ; digital management ; e-leadership ; technologies ; municipalities ; stablecoins ; risks in business economics and finance ; digital trading and investment platforms ; economic sanctions ; digital currencies ; customer loyalty ; perceived service quality ; relational benefits ; relationship quality ; sustainability ; bibliometric analysis ; Scopus ; digital transformation ; labor market ; labor productivity ; unemployment ; Saudi Arabia ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCM Development economics and emerging economies
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: System dynamics is a simulation modeling approach to strategic and policy analysis that has been applied to many health care and public health issues since the 1960s and has become increasingly prevalent since the 2000s. The ten articles in this reprint appeared in a Special Issue of Systems and cover a broad cross-section of relevant methodological topics as well as applications to specific health problems.One methodological article describes the use of cascaded system archetypes, with an application to reducing hospital congestion. Another discusses Monte Carlo uncertainty analysis, with an application to the US opioid crisis. Three of the articles describe models of community response to severe shocks, including recovery from the COVID-19 pandemic. Two other articles address strategies for dealing with myriad chronic diseases and risk factors in a population. Other papers include in-depth analyses of prostate cancer screening, digital prosthetic services for lower-limb amputees, and the complex behavioral health challenge of youth homelessness.This reprint provides an excellent snapshot of the current state of practice in system dynamics as it is applied to public health, health care delivery, and health policy. It offers practical policy guidance and will be of interest to both experienced practitioners and those new to the field.
    Keywords: simulation model ; public health practice ; chronic disease ; prevention ; cardiovascular diseases ; cancer ; COVID-19 ; tourism recovery ; public policy ; system dynamics ; participatory modelling ; health ; social care ; integrated care ; hospital ; delayed hospital discharges ; strategy ; congestion ; capacity ; archetypes ; unintended consequences ; population health and well-being ; equity ; stewardship ; resilience ; simulation modeling ; uncertainty analysis ; optimization ; sensitivity testing ; Monte Carlo randomization ; opioid epidemic ; prosthetics ; major lower-limb amputations ; prosthesis usage ; amputee mobility ; health care system ; health policy ; youth homelessness ; child welfare ; juvenile justice ; mental health ; public health ; decision making ; long-term conditions ; resource allocation ; complex systems ; early detection of cancer ; mass screening ; decision-making ; dissemination ; clinical practice guidelines ; evidence-based guidelines ; policy decision thresholds ; prostate cancer ; natural history of disease ; biomarker ; PSA ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: Since the introduction of Bitcoin in 2009, the cryptocurrency market has experienced exponential expansion. Evolving from sets of transactions primarily conducted on Internet fora into a significant market valued at over 1.2 trillion USD as of August 2023, today cryptocurrency trading occurs 24/7 on more than 600 platforms. Despite its persistent volatility, recurrent speculation bubbles and subsequent market crashes, the trading characteristics of cryptocurrency exchanges are similar to those observed in mature financial markets. Recently, the correlation between the most frequently traded cryptocurrencies, specifically Bitcoin and Etherereum, has increased significantly versus the stock indices and other financial assets, suggesting an emerging connectedness with the global financial markets. This Special Issue collected research studies that make steps towards developing a better understanding of cryptocurrency market, with a particular aim of confirming or denying the growing signs of market maturity. Most submissions focus on price fluctuations in the cryptocurrency exchanges and produce evidence of the cryptocurrency market’s evolution into a valid and interrelated component of the global financial markets. Interestingly, the events related to COVID-19 contributed to the intensification of this process. Some articles address the structure of the cryptocurrency market, including DeFi, the methods of obtaining consensus used, and the environmental impact of these transactions.
    Keywords: public-key cryptosystem ; error correcting code ; bounded distance decoding ; blockchain technology ; cryptocurrency ; Kolmogorov entropy ; DAO ; metaverse ; Bitcoin carbon footprint ; Bitcoin mining ; energy consumption ; FIGARCH ; MFDFA ; long memory ; Hurst exponent ; permanent policy ; cryptocurrencies ; noise and trend effects ; tick-by-tick data ; network structure ; community detection ; COVID-19 ; AI ; business development ; information processing ; volatility ; precision ; financial development ; bitcoin ; ADCC-GARCH ; diversifier ; hedge ; safe haven ; anomaly score ; Mahalanobis distance ; minimum covariance determinant ; shrinkage estimators ; blockchain ; edge computing ; electric vehicles ; Ethereum ; P2P charging ; DeFi ; oracle ; automated market makers ; decentralized exchange ; lending protocol ; forex market ; complexity ; entropy ; multifractal analysis ; complex systems ; financial crisis ; econophysics ; financial markets ; cross-correlations ; multiscale ; time series ; fluctuations ; correlations ; multifractality ; market maturity ; market impact ; collective dynamics ; time series analysis ; portfolio optimization ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-06-23
    Description: In the treatment of acute stroke, thrombolysis and thrombectomy have proven to be highly effective. Many patients have seen significant improvement after reperfusion therapy. This reprint aims to address current knowledge gaps and promote advancements in the use of thrombolysis and thrombectomy for the treatment of acute ischemic stroke.
    Keywords: ischemic stroke ; acute kidney injury ; contrast media ; endovascular treatment ; outcome ; hyperglycemia ; acute ischemic stroke ; large vessel occlusion ; mechanical thrombectomy ; stroke ; ischemia ; machine learning ; cerebral infarction ; biomarkers ; recanalization therapy ; reperfusion ; temperature ; time to admission ; prehospital delay ; prior stroke ; basilar artery ; brain ischemia ; intracranial atherosclerosis ; embolism ; infarction ; clinical symptoms ; intravenous thrombolysis ; endovascular therapy ; recanalization times ; clinical outcome ; hypoperfusion index ratio ; collateral circulation ; collateral scoring ; CTA ; CTP ; thrombolysis ; C-reactive protein ; white blood cell count ; prognosis ; hypoperfusion ; collaterality ; thrombectomy ; frailty ; elderly patients ; hospital frailty risk score ; acute stroke ; perfusion imaging ; CT perfusion ; MR perfusion ; RAPID ; fasting hyperglycemia ; fasting normoglycemia ; long-term outcome ; hemorrhagic transformation ; parenchymal hematoma ; GWAS ; single nucleotide variants ; anterior circulation ; bridging therapy ; recanalization ; stroke risk score ; COVID-19 ; Lithuania ; reperfusion therapies ; outcomes ; safety ; prehospital stroke diagnosis ; ultrasound ; brain perfusion ; SONAS® ; prehospital stroke scales ; point-of-care diagnostics ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-29
    Description: This reprint is devoted to fundamental and applied research in the field of implementing the principles of the circular economy in energy transition, and it substantiates the need for its transformation in the context of sustainable development. Of particular interest are promising areas for the use of secondary energy resources in the economy to create closed production cycles. Specific technologies are considered, and their environmental and economic assessments of scenarios for the introduction of low-carbon technologies in the circular economy, the achievement of the Sustainable Development Goals through the introduction of a circular economy, and the development of regional cooperation are given. Particular attention is paid to the possibility of using eco-innovations for the national transition to decarbonization in the integrated European energy system, Green intellectual capital as a support for corporate environmental development, a sustainable value chain for the industrial consumption of biocomposites, and various options for programs to reduce CO2 emissions.
    Keywords: My Electricity ; photovoltaic (PV) ; LCA ; carbon dioxide emission ; grants ; Poland ; renewable energy ; renewable energy source (RES) ; solar photovoltaic ; self-consumption ; COVID-19 ; energy consumption ; sustainable industrial consumption ; sustainable value chain ; biocomposite ; sustainable packaging ; COVID-19 pandemic influence ; consumer behavior ; green marketing scale ; scale development ; scale validation ; internal marketing ; external marketing ; strategy ; tactics ; operations ; clean technology ; experience circular economy ; rational use ; resource consumption ; sharing model ; green intellectual capital ; green human capital ; green organizational capital ; green relational capital ; environmental development ; sustainable development ; ecology ; innovative development ; decarbonisation ; energy efficiency ; “green” transition ; Data Envelopment Analysis (DEA) ; factor analysis (FA) ; circular economy (CE) ; sustainability ; sustainable development indicators (SDI) ; European Union (EU) ; circular economy ; European green deal ; industrial symbiosis ; transformation ; green organization ; performance evaluation ; sustainable development goals ; resources ; value chain ; management functions ; sustainability-oriented innovation ; conceptual framework ; energy transition ; energy systems modelling ; islands ; life cycle assessment ; low-carbon heating ; responsible consumption ; green purchase ; purchase intention ; thema EDItEUR::K Economics, Finance, Business and Management
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-05-11
    Description: As Editor-in-Chief of the journal Diabetology, I am pleased to announce that the Special Issue “Diabetology: Feature Papers 2022” has now been published as a reprint. Diabetology (ISSN 2673-4540) is an international, peer-reviewed scientific open access journal that provides an advanced forum for studies related to the epidemiology, etiology, pathophysiology, pathogenesis, management, complications, and prevention of diabetes, including the molecular, biochemical, and physiological aspects of diabetes. In this Special Issue, “Feature Papers”, we aimed to publish outstanding contributions in the main fields covered by the journal, which will make a great contribution to the community. This reprint covers the whole spectrum of diabetology from risk screening, risk markers, pathways of disease in type 1 diabetes and insulin treatment, and management of the disease and comorbidities.
    Keywords: older people ; diabetes mellitus ; management ; insulin therapy ; frailty ; sarcopenia ; type 1 diabetes ; type 2 diabetes ; insulin ; beta cell preservation ; verapamil ; thioredoxin-interacting protein (TXNIP) ; Chronic Care Model ; self-management of type 2 diabetes ; chronic disease ; healthcare system of Pakistan ; patients’ quality of life ; obstructive sleep apnoea ; DM ; obesity ; inflammation ; polysomnography ; coronavirus disease 2019 ; COVID-19 ; severe acute respiratory syndrome coronavirus 2 ; SARS-CoV-2 ; diabetes ; diabetic ketoacidosis ; DKA ; hyperglycemia ; mortality ; innate immunity ; cytokine storm ; angiotensin-converting enzyme 2 ; pancreatic β-cell damage ; pediatrics ; HbA1c ; telemedicine ; continuous glucose monitoring ; prediabetes ; liver enzymes ; rhenium (V) compound ; triglycerides ; NAFLD ; fructose ; injection technique ; lipohypertrophy ; sodium glucose co-transporter 2 (SGLT2) inhibitors ; nocturia ; sodium intake ; key informant interviews ; prevention of type 2 diabetes ; National DPP ; DSMES ; telehealth ; provider experiences ; lipodystrophy ; clinical detection ; recommendations ; rehabilitation ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: Today, a great variety of contraceptive techniques are available to women; this, coupled with improving the educational levels of female children and adults, is hastening a decline in fertility and consequently, population growth. With the advent of sustained fertility rates lower than replacement levels in many countries, including China and India, we are already witnessing major economic, social, environmental, and geopolitical consequences. Given this situation, today, the promotion of the use of contraception means improving health, not demography, placing emphasis on individuals and not just on methods alone; on the quality of services, and not simply on availability. Indeed, there is an increasing awareness that contraception can help women reduce health risks that are associated with reproductive events and specifically, with unwanted pregnancies. This means that, no matter how ideal a method may be from a purely scientific viewpoint, it must be submitted to the free, decision-making of well-informed women. To contribute to this new user-centric perspective, this reprint presents a series of articles in which technology is considered withing the broader concept of women’s health. Five articles deal with issues related to the users’ and providers’ perspectives; three discuss a modality that is receiving increasing attention, the so-called Long-Acting Reversible Contraception (LARC); and the last three contributions highlight the new advances in oral hormonal contraception.
    Keywords: long-acting reversible contraception ; intrauterine device ; LARC placement delays ; removal rates ; inner-city clinic ; emergency contraception ; contraceptive method ; levonorgestrel ; ulipristal acetate ; community pharmacies ; health services administration ; combined hormonal contraception ; estetrol ; metabolism ; SHBG ; cycle control ; hemostasis ; emergency contraception pills ; morning-after pill ; sexual behavior ; students ; contraceptive knowledge ; contraceptive attitude ; contraceptive experience ; hormonal contraception ; long-acting reversible contraceptive ; quality of life ; sexual arousal and desire ; short-acting reversible contraceptive ; Nexplanon ; subcutaneous device ; etonogestrel implant ; alternative insertion ; implantation site ; contraceptive implant ; norethisterone acetate ; POP ; progesterone-only pills ; vaginal bleeding ; vaginal spotting ; contraception ; sexual habits ; women ; long-acting reversible contraceptives ; short-acting reversible contraceptives ; counselling ; COVID-19 ; LARC ; reproductive health ; sexual health ; oral contraceptives ; bleeding pattern ; ethinylestradiol ; estradiol ; drospirenone ; norethindrone acetate ; nomegestrol acetate ; dienogest ; abnormal uterine bleeding ; amenorrhea ; dysmenorrhea ; levonorgestrel-releasing intrauterine system ; Progestasert ; n/a
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: In this Special Issue, we aim to represent the vibrant state of protein structure studies at the end of 2021. Recent decades have brought significant changes to the protein structure research field. Thanks to the genome projects and advances in structure determination methods, the number of solved protein structures has increased significantly. Protein structure research is experiencing a new renaissance, and in 2020 the number of deposited structures in the PDB database reached a new record. An assortment of many new frontiers are presented in this collection. A single Special Issue cannot give a comprehensive overview of a large field such as proteins science, but we aim to give a broad overview of current research.
    Keywords: configurational entropy ; force fields ; intrinsically disordered proteins ; protein folding ; NMR ; high hydrostatic pressure ; thermodynamic stability ; α-helical bundle ; Li-Fraumeni syndrome ; hereditary breast cancer ; germline TP53 missense variants ; quantitative prediction model ; protein conformation ; protein–protein interactions ; protein–protein binding ; protein–protein complex ; coarse-grained modeling ; multiscale modeling ; UFM1 ; UBA5 ; UFC1 ; protein-protein interactions ; complex structure ; oxidative stress ; Nrf2 ; Keap1 ; nuclear magnetic resonance spectroscopy ; hydrogen/deuterium exchange ; mass spectrometry ; circular dichroism ; intrinsically disordered ; bifidobacteria ; fucosidases ; glycosyl hydrolases ; conserved domains ; human milk ; analytical ultracentrifugation ; CO2 concentrating mechanism ; diffusion-ordered NMR spectroscopy ; electrospray ionization mass spectrometry ; homotetramer ; manganese ; metalloprotein ; photosynthesis ; small-angle X-ray scattering ; C1q ; calcium binding proteins ; genetic variation ; otoconia ; otolin-1 ; OTOL1 ; site-directed mutagenesis ; thermal shift assay ; B.1.1.7 ; B.1.617.2 ; COVID-19 ; E484Q ; T478K and L452R mutation ; N501Y mutation ; spike protein ; tetrabromobisphenol A ; tetrabromobisphenol S ; erythrocyte membrane ; retardants ; erythrocytes ; protein–ligand interactions ; protein dynamics ; FK506-binding protein ; FKBP12 ; FKBP51 ; oxidative folding ; glutathionylation ; nitrosylation ; cysteine reactivity ; ribosomal exit tunnel ; transient complex ; glutathione ; phosphorylation ; transmembrane proteins ; saturation mutagenesis ; deep sequencing ; residue packing ; deep learning ; convolutional neural network ; bidirectional long-short term memory ; protein ; prediction ; contact ; distance ; alphafold ; ProSPr ; CASP ; dataset ; retrainable ; mutual synergetic folding ; solvent accessibility of peptide bonds ; inter-subunit interaction ; solvent-accessible surface area ; Shannon information entropy ; amino acid composition ; glucose ; GlcNAc ; galactose ; GalNAc ; mannose ; xylose ; fucose ; Neu5Ac ; glucuronate ; iduronate ; tetrahydropyran ; entropy ; free energy ; free energy landscape ; energy-dependent protein folding ; co-translational protein folding ; molecular chaperones ; physical model of protein folding ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: This reprint focuses on data-driven software solutions and their impact on research and development at the academic, industry, business, and government levels to exploit the hidden knowledge and big data that can be offered to cities and citizens in the future. Data-driven software solutions are different from “traditional” software development projects, as the focus of the main development core is on managing the data (e.g., data store and data quality) and designing behavioral models with the aid of artificial intelligence and machine learning techniques. To this end, new life cycles, algorithms, methods, processes, and tools are required. This reprint is centered on the recent trends and advancements in the field of engineering data-intensive software solutions to address the challenges in developing, testing, and maintaining such data-driven systems, with a focus on the application of data-driven solutions to real-life problems and techniques and algorithms addressing the different challenges of data-driven software engineering.
    Keywords: COVID-19 ; SARS-CoV-2 ; data analytics ; schools’ impact ; Google mobility impact ; feature selection ; ontology ; text classification ; machine-learning ; SARS-COV-2 ; Bayesian regression ; changepoint detection ; European football championship ; big data ; delay-tolerant network (DTN) ; multi-attribute decision making ; public transport ; energy consumption ; software development process ; operations ; software engineering ; information system development ; team structure ; Software Library Recommendation ; graph filters ; dependency graphs ; link prediction ; n/a ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNT Media, information & communication industries::KNTX Information technology industries
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: Although many educational researchers were pioneers in the integration of technology into teaching and learning prior to 2000, institutions started extensively adopting technology in their courses around this period. However, the adoption process was slow and mainly followed the traditional mode of teaching in the formal university learning environment. The COVID-19 pandemic’s disruption “forced” everyone to use technology for teaching and learning purposes, supporting synchronous and/or asynchronous teaching and learning processes. This book aims not only to present successful practice examples from before or during the COVID-19 pandemic, but also to provide useful information to university teachers, assisting them in further understanding the higher education context, demands and challenges of digital education. Including evidence from the current higher education landscape from all over the world and discussing various frameworks allows institutions and policymakers to take decisions about the future digital education transformation, while teachers and educational researchers can find examples of how various digital learning tools (i.e., virtual simulations and e-portfolios) are integrated into teaching and learning processes in various environment (i.e., online, and blended learning). Considering experiences prior to the COVID-19 pandemic alongside the opportunities and challenges brought about by the pandemic, this book can support the higher education sector in considering curriculum reformations and introducing innovative teaching and learning approaches to meet the Industrial 4.0 revolution.
    Keywords: standardized test ; Saber Pro ; student characteristics ; mean score differences ; correlations between competencies ; academic performance ; improvement ; e-learning ; technology acceptance ; learning management system ; behavioral intention e-learning ; behavioral intention ; digital learning ecology ; self-directed learning ; learning technology ; digital resilience ; higher education ; HeXie ; bioscience ; home labs ; COVID-19 ; practical skills development ; learning communities ; gamification ; flipped classroom ; virtual labs ; remote lab ; virtual lab ; enquiry-based learning ; inquisitive learning ; interactive learning ; digital interruptions ; online learning ; mobile learning ; blended learning ; career planning ; electronic learning ; employability ; Technological Pedagogical Content Knowledge ; science education ; student teachers ; self-report measure ; ubiquitous learning ; learning theories ; digital transformation ; educational environment ; eco-environment ; educational design ; process model ; capabilities ; Labour 4.0 ; teaching ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JN Education
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This reprint, entitled “Process Control and Smart Manufacturing for Industry 4.0”, contains the extended papers from the Series of annual IFSA conferences on Automation, Robotics and Communications for Industry 4.0/5.0 (ARCI) on the following topics: Process Automation, Process Control and Monitoring, Design Principles in Industry 4.0, Smart Manufacturing and Technologies, Smart Factories, Machine Learning and Artificial Intelligence in Manufacturing. The reprint contains 13 chapters written by 54 ARCI conference participants from seven countries: China, Croatia, Denmark, Germany, Italy, Poland and Romania. This reprint will inform readers of cutting-edge developments in the field and provide effective starting points and a road map for further research and development. All chapters follow the same structure: firstly, an introduction to the specific topic under study; secondly, a description of the field, including sensing or/and measuring applications. Each chapter ends with a curated list of references, including books, journals, conference proceedings and websites. “Process Control and Smart Manufacturing for Industry 4.0” is intended for researchers and scientists from academia and industry, as well as for postgraduate students.
    Keywords: steel alloys ; resistance spot welding ; RSW ; electrode wear ; electrode tip-dressing ; process monitoring ; mushrooming ; plateau forming ; quality control ; COVID-19 ; FDM ; 3D printing ; injection molding ; personal protection ; rapid prototyping ; protective face shields ; mechatronics line ; visual servoing system ; wheeled mobile robot ; industrial robotic manipulator ; Industry 4.0 ; NDT ; magnetic particle inspection ; optimization ; condition monitoring ; vibration ; acoustic emission ; drive train ; data fusion ; machine learning ; product morphology ; core data model ; phase rule filter ; phase private data model ; storage system ; forklift AGV ; deep learning ; semantic segmentation ; H-Swish ; community transformation ; community innovation governance ; ternary space ; coupling and coordination analysis ; lean manufacturing ; lean principles ; pull principle ; production control mechanisms ; production processes ; lean implementation ; batch process ; partial least squares ; multi-phase ; multi-mode ; master production scheduling ; make-to-order ; mathematical programming ; agent-based ; overtime ; earliness ; tardiness ; equipment selection decision ; business compass ; energy consumption ; processing time ; beetle antennae search algorithm ; sustainable blank dimension design ; energy-saving ; low-carbon ; grey wolf algorithm ; gas–solid ; cyclone ; separator ; gas dynamics ; erosion ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The fast development of biosensors with high sensitivity through new functional materials introduced, or simplified the procedure in measurements, which is definitely important. However, more attentions should be paid for real applications, increasing tolerances against various matrix that potentially influence the performance of biosensors. This reprint focuses on the biosensors which were widely used in various fields after some problems were circumstanced, analytical methods development for containments in environments and foods, and biomarkers/hazardous substances in cells based on nanozyme or other nanoparticles, combined with antibodies, nucleic acids, aptamers or nanobodies, including enough sensitivity and satisfactory accuracy, maintaining enzyme activity at varied harsh environments.
    Keywords: autoinducer ; co-cultivation bioassay ; food safety ; foodborne pathogens ; N-acyl homoserine lactones ; plasmid-based biosensor ; Yersinia enterocolitica ; immunoassay ; antibody ; dibutyl phthalate ; scopoletin ; amplex red ; silver nanoparticles ; extracellular vesicles ; Fe3O4@TiO2 ; PD-L1 ; aptasensor ; chemiluminescence ; lung cancer ; non-invasive diagnosis ; bound-free phase ; micro/nanoparticles ; point-of-care ; centrifugal microfluidics ; inflammation ; reagent storage ; DNA ; biosensor ; electrochemiluminescence ; sensitivity ; amplification strategy ; COVID-19 ; SARS-CoV-2 ; spike glycoprotein ; peptide ; all-dielectric metasurface ; fluorescence sensor ; sandwich assay ; rapid antigen test ; omicron variant ; deoxynivalenol ; gold nanoparticles ; PAMAM ; multi-enzyme probes ; aptamer ; MnO2 ; sulfadiazine ; ALI/ARDS ; biosensors ; PR3 ; human NE ; MMP-2 ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This Special Issue of Life, entitled "Plants as a Promising Biofactory for Bioactive Compounds," showcases the latest research that explores the utilization of plant biofactories for the production of compounds with multiple biological effects, including antioxidant, antitumor, antidiabetic, anti-inflammatory, antimicrobial, anti-Alzheimer, antihemolytic, neuroprotective, and pesticide activities.
    Keywords: Arabidopsis ; hairy roots ; lipase ; protein production ; phenolic acid ; flavonoids ; DPPH radical scavenging activity ; anti-inflammatory activity ; maximum possible analgesia ; beverage preservative ; natural essential oils ; antimicrobial activity ; Lithospermum erythrorhizon ; acetylshikonin ; shikonin ; BAHD ; LeSAT1 ; hairy root ; Agathophora alopecuroides ; antidiabetic ; LC-HRMS/MS ; molecular docking ; waste ; by-product ; composition ; bioactive compounds ; health benefits ; blueberry ; Vaccinium myrtillus ; Vaccinium arctostaphylos ; phenolic compounds ; antioxidant activity ; neuroprotective activity ; naringin ; naringenin ; polyphenols ; neurological disease ; dietary interventions ; Cinnamomum zeylanicum ; polyphenol ; cinnamon oil ; LC-HRMS ; GCMS ; enzyme inhibition ; arbuscular mycorrhizal fungi ; commercial herb cultivation ; gene expression ; rosemary ; terpene synthase ; volatile production ; coronavirus ; COVID-19 ; antivirals ; vaccines ; plant production ; molecular farming ; recombinant proteins ; secondary metabolites ; ABTS ; DPPH ; early bud burst ; English oak ; half-sib ; late bud burst ; pedunculate oak ; total flavonoid content ; total phenol content ; natural products ; acetone:butanol:ethanol ; solvent extraction ; process design and economics ; Caenorhabditis elegans ; Meloidogyne incognita ; Zivzik pomegranate ; Punica granatum ; antioxidant ; α-glycosidase ; acetylcholinesterase ; carbonic anhydrase ; LC-MS/MS analysis ; antitumor activity ; cancer ; ethnobotany ; lymphoma ; medicinal plants ; natural extracts ; Mexican plants ; Andrographis ; antioxidants ; GS-MS analysis ; β-D-glucans ; cereals ; biosynthesis ; genes ; breeding ; environment ; functions ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: The global financial crisis plunged the global economy into a great recession. Many central banks responded with unconventional monetary policies such as quantitative easing, negative policy rates, and forward guidance to calm down financial markets. The COVID-19 pandemic led the global economy, financial markets, and central banks to face even more severe problems. Central banks set up further asset purchase programmes to complement existing unconventional monetary policy measures that have already been in place to help the economy to absorb the COVID-19 shock. The new crisis has increased the importance of preserving financial stability through the international cooperation of central banks around the globe. Managing the expectations of market participants plays a crucial role in the context of financial stability. Therefore, the aim of this Special Issue is to disseminate important empirical and theoretical research questions concerning the connection between monetary policy and international financial markets and to stimulate discussion among academics and policymakers. A special focus is devoted to emerging and developing economies. The Special Issue covers several different articles on a variety of topics from the fields of monetary policy and international financial markets. The contributions address research questions on exchange rates, cryptocurrencies, stock markets, the connection between money supply and inflation after the COVID-19 pandemic, the role of commodity price shocks for banking system stability in developing countries, global liquidity effects, the twin deficit, and the Taylor rule.
    Keywords: exchange rates ; cryptocurrencies ; inflation ; COVID-19 ; commodity prices ; emerging and developing countries ; stock markets ; banking ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: The reprint provides the most relevant and state-of-the-art in the field, including recent developments in the production of natural compounds from various bioresources, and their formulations as bioactives. This reprint also covered the engineered approaches for enhanced biological properties and their potential applications. Identification of novel compounds and bioprocess tools to improve the quantity and quality of bioactive compounds and their formulations are exclusively covered in this reprint.
    Keywords: anti-solvent ; enzymatic saccharification ; EMIM-Ac ; ethanol ; ionic liquid ; lignocellulosic biomass ; recycling ; agro-industry ; microencapsulation ; bioactive compounds ; in vitro digestion ; yogurt ; cannabis ; cannabinoids ; postharvest ; drying ; curing ; storage ; biosynthesis ; pre-treatments ; sorption isotherm ; Raphanus sativus L. ; recombinant IFN-α2a ; apoptosis ; antiviral and antitumor activity ; Japanese knotweed rhizome bark ; SARS-CoV-2 ; COVID-19 ; virus neutralization test ; nano-formulation ; nutraceuticals ; prebiotics ; nanofabricated delivery system ; liposomes ; nano-emulsions ; Abelmoschus manihot ; neurodegenerative disease ; oxidative stress ; proliferation ; inflammation ; nucleotide excision repair ; Actinosynnema pretiosum ; ansamitocin P-3 ; ssgA ; AdpA ; morphological differentiation ; pomegranate ; pomace ; extraction ; biological activity ; functional beverages ; sensory quality ; vitamins ; formulation ; homogeneous systems ; hydrophile–lipophile balance ; Emblica officinalis ; phytochemicals ; hyperlipidemia ; pharmacology ; nanoformulation ; Prunus mume ; vasorelaxant ; hypertension ; angiotensin receptor blockers ; agro-waste ; valorization ; value-added bioproducts ; micro/nano encapsulation ; agri-food-pharma applications ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Antibiotic resistance represents one of the most important challenges in the world and involves humans, animals and the environment.For this reason, it is increasingly important to focus our attention on the present scenarios and the future prospects relating to this problem. The One Health approach helps us and can provide the tools to consider the problem from different points of view, also providing alternative solutions to the use of the antibiotic itself.
    Keywords: Enterococcus ; vancomycin resistance ; systematic review ; meta-analysis ; Nigeria ; climate change ; One Health ; Candida auris ; COVID 19 ; emerging pathogens ; antimicrobial resistance ; Staphylococcus aureus ; rabbits ; pathotype ; antibiotic resistance profiles ; spa type ; Italy ; Escherichia coli ; AmpC β-lactamases ; CMY-2 type ; ISEcp1 ; chickens ; wild birds ; livestock ; Greece ; one health ; antibiotic resistance ; human ; animal ; environment ; text data mining ; natural language processing ; common language ; AMR ; AR ; antimicrobial use ; COVID-19 ; SARS-CoV-2 ; farm animals ; blaCTX-M ; Chile ; domestic animals ; E. coli ; extended-spectrum beta-lactamases ; wildlife ; Salmonella enterica ; pigs ; Suriname ; whole genome sequencing ; awareness ; antimicrobial stewardship ; layer poultry farms ; surveillance ; Middle East ; One Heath ; foodborne pathogens ; Campylobacter spp. ; Salmonella spp. ; strategic action plan on antibiotic resistance ; Swedish stakeholder perceptions ; qualitative study ; Enteritidis ; multidrug-resistant ; Derby ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSG Microbiology (non-medical)
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: This book focuses on the application of implementation science methods to enable the rapid uptake and sustainable implementation of new diagnostics into routine health practices to strengthen health systems.Diagnostics are essential for the success of universal health coverage and improved health outcomes. The increased development and deployment of diagnostics for use at the point of care will not guarantee improved access to diagnostics and health outcomes if their implementation is not optimized. Optimal implementation will need to be guided by theories and methods that aim to promote evidence-based practices and findings of research into routine practice, taking into consideration quality systems and contexts.
    Keywords: prognosis ; lactate clearance ; biomarker ; emergency medical services ; emergency department ; critical care ; ultrasound ; imaging ; X-ray ; chest ; diagnosis ; SARS ; SARS-CoV-2 ; rapid diagnostic techniques ; POCT techniques ; lung ultrasound ; COVID-19 ; POCUS ; mHealth devices ; accuracy ; sensitivity ; specificity ; sub-Saharan Africa ; point of care ultrasound ; implementation science ; adoption ; mHealth applications ; disease diagnosis ; treatment support ; rapid diagnostic testing ; RDT ; modelling ; symptoms ; transmission prevention ; infectious disease ; human immunodeficiency virus ; HIV ; coronavirus ; tuberculosis ; health services ; primary healthcare ; point of care diagnostic services ; supply chain management ; resource-limited settings ; Indian pandemic ; rapid antigen tests (RATs) ; CoviSelf ; CoWIN ; digital divide ; rural India ; Indian villagers ; poverty ; discourse analysis ; qualitative medical/health research strategies ; vulnerable populations ; literacy ; diagnostics ; advocacy ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Food quality, including dietary quality and diversity, is as essential to human health as air is to human life. In addition, other healthy lifestyle factors, including a healthy body mass index, regular exercise, no smoking, and sufficient sleep duration, are associated with a lower incidence of chronic non-communicable diseases and longer life expectancy. More importantly, maternal healthy lifestyle factors are also associated with a substantially reduced risk of chronic diseases in their offspring. Childhood is a critical period for the development of a healthy lifestyle and the prevention of chronic diseases in adulthood. However, the prevalence of childhood obesity is increasing and unhealthy lifestyles are becoming an epidemic, posing a potential future burden of adult chronic disease. The aim of this Special Issue is to identify and assess dietary factors, including dietary diversity and specific nutrients/phytochemicals, as well as other healthy lifestyle factors, in the prevention and management of childhood chronic diseases. Additionally, we want to identify gaps and tools that could help with the assessment of children’s health. We wanted to encourage all researchers who work in this field to submit original research, reviews, systematic reviews, and meta-analyses to this Special Issue to broaden our knowledge and pave the way for new research directions.
    Keywords: preschool children ; nutritional status ; eating habits ; Mediterranean diet ; Split-Dalmatia County ; fruit consumption ; lipid ; dyslipidemia ; children and adolescents ; China ; child ; diet quality ; caregiver perception ; CCDI ; dietary fat ; polyunsaturated fatty acid ; monounsaturated fatty acid ; puberty timing ; soy food ; obesity ; hypertension ; child and adolescent health ; food marketing ; policy research ; diet ; kindergarten ; menus ; nutritional errors ; children ; blood pressure ; single-child status ; lifestyle behaviors ; birth cohort ; prospective study ; maternal dietary pattern ; neurodevelopment ; malnutrition ; overnutrition ; fruit and vegetable intake ; potassium intake ; renal damage ; leptin ; preterm neonate ; intrauterine growth restriction (IUGR) ; growth trajectories ; children health prognosis ; diet quality questionnaire ; food groups ; sentinel foods ; dietary diversity ; sedentary behavior ; metabolic syndrome ; preterm ; prebiotics ; glycomacropeptide ; metagenomics ; breastfeeding ; obesity phenotypes ; healthy lifestyle ; baby food ; food contaminant ; toxic elements ; food exposure ; children safety ; children’s health ; arsenic ; cadmium ; mercury ; lead ; latent class analysis ; mediation analysis ; health-related behavior ; cohort ; health-related quality of life ; Swedish Healthy Eating Index for Adolescents 2015 (SHEIA15) ; Riksmaten Adolescents Diet Diversity Score (RADDS) ; inositol ; myo-inositol ; D-chiro-inositol ; gestational diabetes mellitus ; insulin resistance ; randomized controlled trial ; meta-analysis ; screeners ; nutrition ; physical activity ; sedentary behaviour ; lifestyle risk ; COVID-19 ; dietary balance ; Japan ; mealtime regularity ; lifestyle ; electronic devices ; household ; fast food ; adolescents ; dietary behavior ; family ; childhood asthma ; innate immunity ; fruit and vegetables ; carotenoids ; cardio-metabolic risk factors ; birth weight ; parents’ educational level ; parents’ occupational level ; birthweight ; adiposity ; cardiorespiratory fitness ; cholesterol ; lifestyle intervention ; KIDMED test ; kidney impairment ; Diet Quality Questionnaire ; global dietary recommendations ; overweight ; child-nutrition disorders ; prediabetic state ; nutrition therapy ; Mediterranean ; rural health ; complementary feeding ; determinants ; infant feeding ; Thailand ; young child ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-23
    Description: Maritime transport contributes to over 80% of global trading volumes. As such, marine policy has received a large amount of attention from industrial practitioners, researchers, policymakers, and the local community. In general, marine policy covers a wide-ranging area, including governance, international relations, economics, environments, and operations, amongst others. To a certain extent, marine policy fosters the sustainable development of the maritime industry. There has been a wide range of research in different disciplines of marine policy.The purpose of this book is to publish the most intriguing research with respect to the above subjects and to provide a rapid turn-around time regarding reviewing and publishing, as well as to disseminate articles freely for research, teaching, and reference purposes. Furthermore, the book aims to keep readers up to date with the latest developments and research in maritime affairs.
    Keywords: crisis management ; maritime management ; circular letter ; corpus linguistics ; coevolution ; blockchain (BC) ; adoption ; challenges ; developing environments ; Chinese cruisers ; arctic region ; travel constraint ; preference ; behavioral intention ; vessel deployment ; de-hubbing ; transhipment ; port development ; container demand ; liner shipping ; uncertainties ; ship schedules ; schedule recovery ; recovery strategies ; literature survey ; maritime container shipping (MCS) ; network analysis ; Suez Canal (SC) ; weighted network ; graph theory ; 1970s ; liner service (LS) ; disruption simulation ; Maritime Silk Road ; shipping network structure resilience ; dominant port ; vulnerable port ; crisis response ; corporate social responsibility ; container shipping ; text analysis ; COVID-19 ; ferry ; navigation ; safety ; risk ; fuzzy AHP ; coastal management ; fishing areas ; spatial planning ; coastal environmental ; coastal geopolitics ; blue economy ; bibliometrics ; export promotion programs ; export competitiveness ; export performance ; marine transportation ; craft products ; niche differentiation strategy ; craft product ; ship ; transport ; English ; engineer ; IMO ; carbon neutral ; marine fishery ; carbon emission ; carbon sink ; net carbon emission ; LMDI ; maritime industry ; safety management ; ISM Code ; safety supervision ; shipboard safety ; n/a ; thema EDItEUR::A The Arts::AT Performing arts::ATF Films, cinema ; thema EDItEUR::A The Arts::AT Performing arts::ATJ Television
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This Special issue focuses of the most relevant advances in the field of inborn errors of immunity. Indeed, as immunology is rapidly progressing, with the constant discovery of new disease entities and the better characterization of molecular mechanisms and targeted therapies, a continuous update is mandatory for clinician and researchers. In this Issue, the non-infectious manifestations of inborn errors of immunity (such as autoimmunity, atopy, and lymphoproliferation) are deeply discussed, as well as the impact of the novel genetic sequencing techniques in the diagnostic approach. Moreover, some well-known disorders, including common variable immunodeficiency, are extensively reviewed and revisited in a modern way. Also, diseases of recent description, including some disorders of immune dysregulation and inborn errors of immunity associated with syndromes, are described. Finally, some of the papers of this Special Issue focus in a detailed way the molecular mechanisms leading to immunodeficiency and immune dysregulation, also opening the way for further clinical and preclinical studies. As the expanding availability of immunological and genetic testing offers the opportunity to identify new disease entities and elucidate the function of new genes involved in the development and regulation of the immune response, we aim to present the most relevant innovations in this delicate field.
    Keywords: B cell maturation ; CD4+ cells ; T cell maturation ; primary immune deficiency ; autoimmunity ; connective tissue diseases ; atopic diseases ; atopy ; allergy ; selective IgA deficiency ; primary immunodeficiency ; autoimmune diseases ; Immunoglobulin E ; Immunoglobulin deficiency ; infections ; malignancy ; 22q11.2 deletion syndrome ; activated phosphoinositide 3-kinase d syndrome ; common variable immunodeficiency ; complement deficiency ; CTLA-4 ; Immune dysregulation ; LRBA ; severe combined immunodeficiency ; X-linked agammaglobulinemia ; anti-SARS-CoV-2 antibodies ; COVID-19 ; SARS-CoV-2 ; PIMS-TS ; Foxp3 ; IPEX ; CVID ; primary immunodeficiencies ; epigenetics ; DNA methylation ; inborn errors of immunity ; DiGeorge syndrome ; 22q11.2 deletion ; thymic output ; dendritic cells ; immunodeficiency ; copy number variations ; array-CGH ; IKZF1 ; IKAROS ; de novo mutation ; R162Q ; immune response ; heterologous vaccine ; humoral response ; T-cell response ; autoimmune lymphoproliferative syndrome ; lymphoproliferation ; gastrointestinal infections ; Giardia ; giardiasis ; refractory ; treatment ; immunology ; immunogenetic ; eosinophilic gastrointestinal disorders ; eosinophilic esophagitis ; unclassified primary antibody deficiency ; primary antibody deficiency ; transient hypogammaglobulinemia of infancy ; children ; TNFRSF13B mutations ; isolated IgM deficiency ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: Twenty interesting studies on, among others, risks towards firm performance, financial risk and financial uncertainties, risk consequences for European countries’ businesses and economies from the Russia and Ukraine conflict, the effects of adopting enterprise risk management on the performance and risks of European publicly listed insurance firms, the management of financial risks while performing international commercial transactions, market liquidity and its dimensions, benchmarking as a way of finding risk factors in business performance, the effect of risk disclosure for trade credit, risk perception, accounting, and resilience in public sector organizations, and psychological effects from potential unexpected environmental disasters on investors. Although disasters are associated with risk, investors tend to have a different perspective depending on the source of the disaster. More specifically, if a country is facing a natural disaster, where no one can be blamed, the foreign investors who may hold a country’s bonds will continue to trust the country due to the “innocence” of the country. On the other hand, when a firm causes a technological disaster, such as a nuclear power plant explosion, investors, if this corporation is publicly traded, will “punish” the firm by selling its shares at any price to avoid a bigger loss.
    Keywords: na-tech ; systematic risk ; market reaction ; unexpected events ; investing ; banking ; clearinghouses ; systemic risk ; derisking ; drivers and implications of derisking ; risk management ; antimoney laundering (AML) ; combatting the financing of terrorism (CFT) ; financial services ; Malta ; small EU state ; proportionality ; conditional value-at-risk ; CVaR ; CVaR regression ; drawdown ; conditional drawdown-at-risk ; fund style classification ; resilience capacity ; cut-back management ; crisis ; Plato ; fairness ; commercial transactions ; international trade ; game theory ; risk disclosure ; trade credit ; content analysis ; Tunisian listed companies ; benchmarking ; best value ; business ; data envelopment analysis (DEA) ; performance ; risk factors ; microblogging data ; data mining ; investor sentiments ; asset pricing ; market liquidity ; liquidity dimensions ; option pricing ; utility indifference pricing ; transaction costs ; Hamilton-Jacobi-Bellman equation ; penalty methods ; finite difference approximation ; financial risk ; financial institutions ; international commerce ; profiteering ; non-fraudulent currency ; classical Athens ; risk ; bonds ; equities ; hedge funds ; forecasting ; GARCH ; value at risk ; enterprise risk management ; firm characteristics ; firm performance ; firm risk ; insurance firms ; COVID-19 ; helping behavior ; in-group identity ; risk perception ; severity of a local pandemic ; financial ; non-stationary ; time-series ; copula ; dependence ; univariate ; bivariate ; war in Ukraine ; Europe ; consequences ; economy ; companies ; embargo ; institutional volatility ; institutional rigidity ; political and social change ; regime risks ; Sparta ; Athens ; transformational change ; nonprofits ; NDIS Implementation Framework ; business models ; sustainability ; energy crisis risks ; nuclear energy ; renewable energy ; greenhouse gases emissions ; nuclear accidents ; nuclear weapons ; nuclear waste management ; capabilities ; reputation risk ; mediation model ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJC Business strategy ; thema EDItEUR::W Lifestyle, Hobbies and Leisure::WC Antiques, vintage and collectables::WCF Collecting coins, banknotes, medals and other related items
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-29
    Description: The business model concept has gained a prominent position both in academia and among practitioners during the past 30+ years. The aim of this Special Issue of Systems is to contribute to a stronger theoretical basis for the business model concept. This includes a focus on the systemic character of business models and the systems approaches that this entails. Another important aspect is to allocate more attention to innovations of business models. The business models that emerged with e-commerce and e-business as such were in themselves innovations. However, innovations of business models have received too little attention. Most of the business models analyzed and discussed in the business model literature have been rather static instead of dynamic. This is the reason why this Special Issue of Systems, entitled ‘Business Model—the Perspective of Systems Thinking and Innovation’, has been developed.
    Keywords: digital business models ; digital economy ; network effects ; digital business model innovation ; digital innovation ; systems thinking ; Rich Picture ; complexity ; Netflix ; port supply chain ; blockchain ; smart contract ; probabilistic model checking ; luxury hotel ; COVID-19 ; marketing ; human resource ; efficiency ; TRIZ ; decision making ; social commerce ; e-commerce ; social media ; business model ; network steam ; business model innovation ; blitz canvas ; process-driven business models ; business model canvas ; lean startups ; adaptability ; ecological fitness ; entropy ; environment ; growth ; stability ; start-ups ; survival ; synchronous ; sustainability ; system design thinking ; system innovation ; designer ; open system approach ; product innovation ; attention allocation ; strategic attentions ; external information sources ; absorptive capacity ; organizational learning ; service design ; digital technology ; experience innovation ; cultural heritage ; supply chain system ; data sharing ; access control ; system verification ; supply chain ; data ownership ; data asset trading ; block chain ; demand-side economies of scope ; economies of scale ; Big Tech corporations ; business models ; system dynamics ; agriculture value chain ; farmers behavior ; fresh products production ; incumbents ; innovation management ; exploration ; renewal ; thema EDItEUR::K Economics, Finance, Business and Management
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The global coronavirus pandemic has highlighted the paramount importance of immune health and the nutrient status of peoples worldwide. Vitamins C and D have important roles in both the innate and adaptive immune systems and are known to support healthy immune function. Both vitamins C and D have gene regulatory roles with the ability to up- and down-regulate thousands of genes, thus playing pleotropic roles in human health and disease. People from low- and middle-income countries tend to have inadequate micronutrient intakes and status, as do specific subgroups from high-income countries. This can affect their resistance to both communicable and non-communicable diseases and the severity of these diseases. In this Special Issue, we have compiled review articles and research papers (both observational and interventional studies) that explore the role of vitamins C and D in numerous aspects of global and population health.
    Keywords: immune system ; viral infection ; influenza ; COVID-19 ; micronutrients ; vitamins ; omega-3 fatty acids ; minerals ; vitamin C ; vitamin D ; vitamin C status ; vitamin C deficiency ; global health ; dietary intake ; obesity ; smoking ; communicable disease ; infection ; noncommunicable disease ; hypovitaminosis C ; low and middle income ; LMIC ; supplement ; non-communicable disease ; Vitamin C status ; energy ; well-being ; kiwifruit ; mood ; SARS-CoV-2 ; coronavirus ; ascorbate ; colds ; pneumonia ; sepsis ; immunonutrition ; supplementation ; dietary surveys ; trends ; descriptive studies ; United States ; fruit juice ; fruit ; vegetables ; psychology ; mental health ; nutrition ; healthy adults ; ethnicity ; Māori ; Pasifika ; Pacific ; Asian ; ascorbic acid ; post-viral fatigue ; lack of concentration ; sleep disturbances ; depression ; frailty ; elderly ; hospitalisation ; serum 25-hydroxyvitamin D ; first-generation immigrants ; melanin ; long COVID ; immunisation ; immune support ; body weight ; vitamin C intake ; plasma ascorbate concentrations ; vitamin C requirements ; dietary vitamin C ; hyperglycaemia ; South Africa ; vitamin D receptor ; vitamin D-binding protein ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: A multidisciplinary approach that involves multiple sectors and stakeholders is essential for disaster risk reduction and adaptation to climate change. This Special Issue explores how interdisciplinary approaches could resolve a wide range of issues, including risk and damage assessment, behavior change, investment, and evidence-based policy formulation.
    Keywords: natural hazard-triggered technological (Natech) ; risk perception ; protective actions ; evacuation ; household survey ; Cilegon ; Indonesia ; agricultural drought vulnerability ; spatial heterogeneity ; entropy weight method ; contribution model ; China ; risk assessment ; high-temperature disaster ; kiwifruit ; climatic suitability zoning ; hazard ; vulnerability ; exposure ; disaster prevention and mitigation capacity ; extreme temperature indices ; abrupt ; prediction ; disaster risk ; Yangtze River Basin ; climate change ; adaptation ; method ; digital disaster reduction ; natural disasters ; agricultural production ; food aid ; official development assistance ; conflict ; poverty ; cereal production ; humanitarian aid ; financing mechanism ; flood protection ; investment cycle ; investment in DRR ; Japan ; long-term plan ; lost decades ; Sendai Framework for Disaster Risk Reduction ; multi-variate Probit model ; Poisson regression model ; agricultural productive services ; earthquake disaster ; earthquake fatalities ; rapid estimation ; earthquake relief ; disaster assessment ; earthquake emergency response ; numerical simulation ; empirical method ; Yangbi earthquake ; COVID-19 ; disaster science ; evidence-based policymaking ; ordinal logistic regression ; principal component analysis ; compound indicator ; single-person households ; indirect death ; long-term effects ; excess mortality ; surveillance system ; disaster risk reduction ; disaster risk perception ; the population at risk ; agent-based modeling ; coastal areas ; community-based adaptation ; nature-based solutions ; green infrastructure ; perception ; family ; community ; Jakarta ; disaster preparedness capability ; heavy rainstorm ; local government ; AHP ; evaluation index system ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics ; bic Book Industry Communication::P Mathematics & science::PH Physics::PHK Electricity, electromagnetism & magnetism
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The discovery of new drugs is one of pharmaceutical research's most exciting and challenging tasks. Unfortunately, the conventional drug discovery procedure is chronophagous and seldom successful; furthermore, new drugs are needed to address our clinical challenges (e.g., new antibiotics, new anticancer drugs, new antivirals).Within this framework, drug repositioning—finding new pharmacodynamic properties for already approved drugs—becomes a worthy drug discovery strategy.Recent drug discovery techniques combine traditional tools with in silico strategies to identify previously unaccounted properties for drugs already in use. Indeed, big data exploration techniques capitalize on the ever-growing knowledge of drugs' structural and physicochemical properties, drug–target and drug–drug interactions, advances in human biochemistry, and the latest molecular and cellular biology discoveries.Following this new and exciting trend, this book is a collection of papers introducing innovative computational methods to identify potential candidates for drug repositioning. Thus, the papers in the Special Issue In Silico Strategies for Prospective Drug Repositionings introduce a wide array of in silico strategies such as complex network analysis, big data, machine learning, molecular docking, molecular dynamics simulation, and QSAR; these strategies target diverse diseases and medical conditions: COVID-19 and post-COVID-19 pulmonary fibrosis, non-small lung cancer, multiple sclerosis, toxoplasmosis, psychiatric disorders, or skin conditions.
    Keywords: COVID-19 ; drug repurposing ; topological data analysis ; persistent Betti function ; SARS-CoV-2 ; network-based pharmacology ; combination therapy ; nucleoside GS-441524 ; fluoxetine ; synergy ; antidepressant ; natural compounds ; QSAR ; molecular docking ; drug repositioning ; UK Biobank ; vaccine ; LC-2/ad cell line ; drug discovery ; docking ; MM-GBSA calculation ; molecular dynamics ; cytotoxicity assay ; GWAS ; multiple sclerosis ; oxidative stress ; repurposing ; ADME-Tox ; bioinformatics ; complex network analysis ; modularity clustering ; ATC code ; hidradenitis suppurativa ; acne inversa ; transcriptome ; proteome ; comorbid disorder ; biomarker ; signaling pathway ; druggable gene ; drug-repositioning ; MEK inhibitor ; MM/GBSA ; Glide docking ; MD simulation ; MM/PBSA ; single-cell RNA sequencing ; pulmonary fibrosis ; biological networks ; p38α MAPK ; allosteric inhibitors ; in silico screening ; computer-aided drug discovery ; network analysis ; psychiatric disorders ; medications ; psychiatry ; mental disorders ; toxoplasmosis ; Toxoplasma gondii ; in vitro screening ; drug targets ; drug-disease interaction ; target-disease interaction ; DPP4 inhibitors ; lipid rafts ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KND Manufacturing industries::KNDP Pharmaceutical industries
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: This special issue "Separation, Extraction and Purification of Natural Products from Plants" contains high-quality multidisciplinary research and review articles on various aspects of natural products. Quality by design (QbD) is a science-based and risk-based concept. The implementation of QbD ensures consistent high quality of natural product. The advantages of the concept are reflected in the researches collected in this special issue, such as the two articles on the optimization of the steam distillation process from Jiangxi University of Chinese Medicine. Process analytical technology (PAT) is an important part of the implementation of QbD concept. Two articles from Dr. Li Wenlong combines spectroscopy and chemometrics, providing good examples on the monitoring of natural product preparation process. Chromatographic separation and analysis are very important for quality control of natural products. There are six articles from different countries focusing on this topic. There are two articles investigating separation technologies, including membrane filtration and ethanol precipitation. Traditional Chinese medicines are also an important category of natural products. A review from Zhejiang University talks about the quality control of Xiaochaihu Capsule. I received a lot of help from friends from universities and enterprises in completing this special issue. I would like to express my gratitude to them. My thanks also go to the editors of this journal of Separations.
    Keywords: azide ; cilostazol ; COVID-19 ; genotoxic impurity ; validation ; LLE ; ethanol precipitation ; loss of active ingredients ; mixing condition indicator ; micromesh mixer ; Caulis sinomenii ; microfiltration ; ultrafiltration ; sinomenine hydrochloride ; separation and purification ; Phyllanthus urinaria L. ; ellagic acid ; mechanochemical-assisted extraction ; macroporous adsorption resin ; compositional monosaccharides ; HPLC–ELSD/PDA combined with HPSEC–MALLS–RID ; molecular weight ; quality markers (Q-marker) ; red ginseng polysaccharides ; Xiaochaihu (XCH) formula ; preparations ; quality control ; standard ; 4-aryl-3,4-dihydropyrimidin-2(1H)-ones ; teicoplanin aglycone ; chiral HPLC ; enantioselectivity ; molecular docking ; molecular dynamics ; Radix Angelicae sinensis ; volatile oil ; Box–Behnken design ; steam distillation ; extraction kinetics ; design space ; dill ; Anethum graveolens L. ; essential oil ; Neofusicoccum parvum ; antifungal mechanism ; near-infrared spectroscopy ; Astragali radix ; alcohol precipitation ; accuracy profile ; Vis-NIR spectroscopy ; Ginkgo biloba L. leaves ; in-line analysis ; column chromatographic elution ; consistency evaluation ; multivariate statistical process control (MSPC) ; quality by design ; Xiaochaihu capsule ; quantitative chromatographic fingerprint ; definitive screening design ; Plackett–Burman ; Forsythia suspensa ; Lonicera japonica ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: This reprint focuses on the impact of the global COVID-19 pandemic on STEM education and measures (teaching tools and research practices) taken to combat the learning gaps in STEM education in the post-pandemic era. Contributions were collected from researchers engaged in STEM education research, including the methods, pedagogical approaches, and environments they utilize in the post-pandemic era.
    Keywords: educational innovation ; COVID-19 ; higher education ; professional education ; remote learning ; online teaching ; chemistry laboratory ; hands-on experiments ; competencies ; students’ perception ; engineering education ; online assessments ; multi-course project-based learning (MPL) ; Sustainable Development Education (ESD) ; educational technologies ; digital technologies ; teaching experiences ; learning experiences ; pedagogy ; online learning ; distributed learning environments ; media in education ; domestic space ; programming education ; feedback to teachers ; programming process ; visualization ; online problem-based learning (PBL) ; online just-in-time teaching (JiTT) ; impacts on learning and skills ; implementation challenges ; multidisciplinary education ; interdisciplinary ; convergence education ; attitude toward convergence ; creative problem solving ; integrated curriculum ; STEM ; STEAM education ; self-efficacy ; emotions ; academic engagement ; hybrid learning ; COVID-19 pandemic ; STEAM ; design-based research ; cooperative teaching ; China ; gender differences ; learning outcomes ; compulsory education ; pedagogical methods ; STEM education ; high school ; teacher education ; STEM pedagogies ; barriers ; post-pandemic ; coronavirus ; engineering students ; remote classes ; online classes ; distance education ; information technologies ; students’ perceptions ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JN Education
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: The delicate balance of resource intensity and efficiency of a solution for a very complex problem raises the issue of how these aspects constitute a symmetrical or asymmetrical system. Computational Intelligence (CI) offers a plethora of efficient tools for the potential and rather good quality solution of highly complex, often mathematically intractable problems. This "toolbox" is one of the best examples for the study of the above mentioned issue, namely, how to find the best balance, how to establish a symmetry of weights or costs in a particular field, for a particular problem. This special issue presents a number of interesting novel applications of CI for the tackling of a wide variety of difficult problems. The Introduction gives a short insight into the symmetry and asymmetry aspect of the topic.
    Keywords: lung nodule segmentation ; 3D-UNet ; 3D-Res2UNet ; multi-scale features ; deep learning ; butterfly optimization algorithm (BOA) ; particle swarm optimization (PSO) ; cubic map ; nonlinear ; high dimension ; extensional fuzzy numbers ; MI-algebras ; similarity ; arithmetics of fuzzy numbers ; orderings ; fuzzy interpolation ; economic data ; air defense system ; artificial immune system ; command and control ; learning classifier system ; multi-agent systems ; weapon-target assignment ; energy optimization ; genetic algorithms ; multi-objective optimization ; artificial neural network simulator ; artificial intelligence ; artificial bee colony algorithm ; global optimization ; neural network ; nonlinear static system ; behavioural finance ; imprecision ; oriented fuzzy number ; oriented present value ; oriented return ; S-divergence ; S-distance ; spectral clustering ; text summarization ; recurrent neural network ; embedding ; dynamic memory network ; fuzzy-rough cognitive network ; fuzzy cognitive map ; granular computing ; fuzzy-rough sets ; stability ; convergence ; discrete bacterial memetic evolutionary algorithm ; simulated annealing ; flow shop scheduling problem ; global sensitivity analysis ; Sobol procedure ; fast algorithm ; convolutional neural network ; structure reduction ; pruning ; quality ; feature selection ; machine learning ; asexual ; genetic algorithm ; android malicious application detection ; bees algorithm ; training deep neural networks ; metaheuristics ; opinion mining ; recurrent neural networks ; sentiment classification ; natural language processing ; data augmentation ; fine-tuning ; generative models ; StyleGAN ; transfer learning ; present value ; discount factor ; portfolio ; finance ; optimization ; tourist trip design ; vehicle routing ; key performance indicator (KPI) ; anomaly detection ; variational auto-encoder (VAE) ; support vector data description (SVDD) ; FMEA ; Fuzzy Logic ; greenhouse gases ; blockchain ; difficulty adjustment ; proof-of-work ; ANN ; AlexNet ; COVID-19 ; TSA ; commonsense ; knowledge graph ; linguistic terms ; language models ; n/a ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNT Media, entertainment, information and communication industries::KNTX Information technology industries ; thema EDItEUR::U Computing and Information Technology::UY Computer science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: In this Special Issue, we aim to represent the vibrant state of protein structure studies at the end of 2021. Recent decades have brought significant changes to the protein structure research field. Thanks to the genome projects and advances in structure determination methods, the number of solved protein structures has increased significantly. Protein structure research is experiencing a new renaissance, and in 2020 the number of deposited structures in the PDB database reached a new record. An assortment of many new frontiers are presented in this collection. A single Special Issue cannot give a comprehensive overview of a large field such as proteins science, but we aim to give a broad overview of current research.
    Keywords: configurational entropy ; force fields ; intrinsically disordered proteins ; protein folding ; NMR ; high hydrostatic pressure ; thermodynamic stability ; α-helical bundle ; Li-Fraumeni syndrome ; hereditary breast cancer ; germline TP53 missense variants ; quantitative prediction model ; protein conformation ; protein–protein interactions ; protein–protein binding ; protein–protein complex ; coarse-grained modeling ; multiscale modeling ; UFM1 ; UBA5 ; UFC1 ; protein-protein interactions ; complex structure ; oxidative stress ; Nrf2 ; Keap1 ; nuclear magnetic resonance spectroscopy ; hydrogen/deuterium exchange ; mass spectrometry ; circular dichroism ; intrinsically disordered ; bifidobacteria ; fucosidases ; glycosyl hydrolases ; conserved domains ; human milk ; analytical ultracentrifugation ; CO2 concentrating mechanism ; diffusion-ordered NMR spectroscopy ; electrospray ionization mass spectrometry ; homotetramer ; manganese ; metalloprotein ; photosynthesis ; small-angle X-ray scattering ; C1q ; calcium binding proteins ; genetic variation ; otoconia ; otolin-1 ; OTOL1 ; site-directed mutagenesis ; thermal shift assay ; B.1.1.7 ; B.1.617.2 ; COVID-19 ; E484Q ; T478K and L452R mutation ; N501Y mutation ; spike protein ; tetrabromobisphenol A ; tetrabromobisphenol S ; erythrocyte membrane ; retardants ; erythrocytes ; protein–ligand interactions ; protein dynamics ; FK506-binding protein ; FKBP12 ; FKBP51 ; oxidative folding ; glutathionylation ; nitrosylation ; cysteine reactivity ; ribosomal exit tunnel ; transient complex ; glutathione ; phosphorylation ; transmembrane proteins ; saturation mutagenesis ; deep sequencing ; residue packing ; deep learning ; convolutional neural network ; bidirectional long-short term memory ; protein ; prediction ; contact ; distance ; alphafold ; ProSPr ; CASP ; dataset ; retrainable ; mutual synergetic folding ; solvent accessibility of peptide bonds ; inter-subunit interaction ; solvent-accessible surface area ; Shannon information entropy ; amino acid composition ; glucose ; GlcNAc ; galactose ; GalNAc ; mannose ; xylose ; fucose ; Neu5Ac ; glucuronate ; iduronate ; tetrahydropyran ; entropy ; free energy ; free energy landscape ; energy-dependent protein folding ; co-translational protein folding ; molecular chaperones ; physical model of protein folding ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-14
    Description: Commodity markets have evolved substantially since the early 2000s and have become more financialized. The recent cold war between the U.S.A. and China, the outbreak of COVID-19, and Russia's invasion of Ukraine have caused resource prices to soar, leading to greater volatility in the commodity markets. The volatility of the commodity markets has increased, and at the same time, financial markets such as the stock market, bond market, and foreign exchange market have become unstable. This has increased the linkage between the commodity and financial markets and has led to a great deal of attention being paid to the commodity markets by governments, companies, and investors.This reprint delves into recent developments in the commodity markets and elucidates the multifaceted factors that have shaped their trajectory. It examines how the interwoven dynamics of supply and demand, geopolitics, technology, and financialization have brought about a new era in commodity trading. By providing a comprehensive survey of these developments, we aim to provide insights that will help stakeholders successfully navigate the challenges and opportunities presented by this evolving landscape.
    Keywords: Russia and Ukraine conflict ; commodities ; G7 and BRIC markets ; TVP-VAR ; connectedness ; oil price uncertainty shocks ; international equity markets ; global vector autoregressive model ; arbitrage ; efficiency ; futures ; liquidity ; market integration ; platinum ; COVID-19 ; pandemic ; agriculture ; commodity ; MF-DFA ; high frequency ; asymmetric volatility spillover ; bitcoin ; altcoin ; cryptocurrency ; frequency connectedness ; Bitcoin ; machine learning ; random forest regression ; LSTM ; energy market volatility ; oil price dynamics ; fear index ; Markov-regime switching models ; volatility risk premium (VRP) ; implied and realized volatility ; oil and stock returns ; financialization ; Bermudan commodity options ; multi-layer perceptron ; multi-asset stochastic volatility model ; hybrid forecasting approaches ; two-step forecasting approaches ; gold ; euro ; sentiment analysis ; ARIMA ; wavelet transformation ; seasonal decomposition ; long short-term memory ; random forest ; eXtreme gradient boosting ; stock ; markets ; cycles ; investing ; risk ; returns ; thema EDItEUR::W Lifestyle, Hobbies and Leisure::WC Antiques, vintage and collectables::WCF Collecting coins, banknotes, medals and other related items
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: "Health and Public Health Applications for Decision Support Using Machine Learning" is a reprint that explores the intersection of machine learning and health sciences. It presents a collection of research and innovations showcasing how data-driven algorithms can transform patient care, disease diagnosis, and public health management. The reprint covers a wide range of topics, including natural language processing for biomedical relation extraction, ensemble learning for blood glucose level forecasting in diabetes management, machine learning for predicting walking stability and fall risk among the elderly, deep learning for pneumonia-infected lung volume quantification, and more.The reprint also discusses applications in precision medicine, early detection of renal damage, cardiac health monitoring, stress classification for mental health assessment, and early diagnosis of intracranial internal carotid artery stenosis. It emphasizes the role of machine learning in managing health crises, such as COVID-19 detection using ECG, voice, and X-ray systems, and reviews AI models in diagnosing adult-onset dementia disorders.Overall, this reprint aims to inspire researchers and healthcare professionals by showcasing the transformative potential of machine learning in healthcare. It hopes to encourage further research and collaboration to advance healthcare and technological innovations for a healthier future.
    Keywords: adult-onset dementia ; Alzheimer’s disease ; magnetic resonance imaging ; artificial intelligence ; machine learning ; neural networks ; atherosclerosis ; Doppler ultrasound ; internal carotid artery ; hemodynamic modeling ; stroke ; stress ; emotion ; action units ; speech ; audio visual ; RNN-LSTM ; petri-plates ; colonies ; machine-learning models ; discrimination ; Measurement uncertainty ; Monte Carlo method ; ECG ; Cardiac health ; COVID-19 ; signal processing ; image processing ; computerized diagnostic systems ; subclinical renal damage ; risk assessment tool ; group-based trajectory modeling ; screening strategy ; CVD classification ; data selection ; convolutional neural network ; pretrained model ; deep learning ; transfer learning ; infected lung segmentation ; quantification of lung disease severity ; comparison between manual and automated image segmentation ; deep neural network ; COVID-19 detection ; COVID-19 severity assessment ; gait ; neuromuscular control ; movement synergy ; overground walking ; principal component analysis (PCA) ; largest Lyapunov exponent (LyE) ; time-series forecasting ; blood glucose ; diabetes ; ensemble learning ; artificial neural network ; DDI (drug–drug interaction) ; CPR (chemical–protein relation) ; transformer ; self-attention ; GAT (graph-attention network) ; relation extraction ; ChemProt ; T5 (text-to-text transfer transformer) ; n/a
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Success, injuries, future career opportunities of athletes, and the societal gains of participating in sports and organizing (mega) sports events are all related to individual risk-taking behavior. Although the sports economics and management literature has broadly addressed these issues, it is surprising that less attention has been paid to the implications of risk-taking on the organization of sports in general and, more particularly, on the design and behavior of sports organization members.
    Keywords: sports ; economics ; management ; risk-taking ; in ; professional ; (e.g., ; doping, ; injuries, ; post-career ; path) ; organizing ; (mega) ; events ; implications ; of ; on ; the ; organization ; risk ; treatment ; organizations ; taking ; after ; COVID-19 ; pandemic ; bic Book Industry Communication::J Society & social sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: This reprint examines the panorama of contemporary Islamic revivalism in the modern world. Constituted by methodologically and ideologically a wide variety of revivalist movements, Islamic revivalism is a complex multidimensional global reality. In a local context, it is a socio-religious reaction to the failure of state-led modernization projects and to general socio-economic quandaries, and in international context, it is a reaction to the wide-ranging crises of modernity. The collection provides important insights into the reality of contemporary Islamic revivalism through an examination of myriad socio-cultural, economic, and political problems facing Muslims at micro- and macro-levels of everyday living. It explains how Islamic revivalist movements are engaged in revivalist activities commonly known as Islamization at an individual level as well as at a community level and reveals that as a global reality, contemporary Islamic revivalism is neither necessarily violent nor anti-modernity but an attempt by religiously motivated concerned Muslims to bring about a self-conceived positive social transformation of individual societies and the modern world at large.
    Keywords: the Qur’an ; exegesis ; ijtihad ; revival ; renewal ; modernity ; Tabligh Jama’at ; emotion work ; emotions ; framing ; social transformation ; extremism(s) ; Islamism ; eco-radicals ; frames ; Tajdid ; Australian Muslims ; Said Nursi ; Hizmet Movement ; mosque open day ; Muslims in the West ; Australian Intercultural Society ; Fethullah Gülen ; Affinity Intercultural Society ; Muslim consumer ethics ; youth ; media ; digital age ; Hizmet ; revivalism ; revivalist movements ; education ; interfaith dialogue ; intercultural dialogue ; Islamic movements ; multiculturalism ; cosmopolitanism ; Tablighi Jamaat ; COVID-19 ; WhatsApp ; traditional ; Islamic revivalist movement ; digital religion ; Pakistan ; netnography ; logics ; authority ; Salafism ; reversion ; deprivation ; women movements ; ‘Aisyiyah ; Muhammadiyah ; modernism ; literacy ; Indonesian Islam ; crisis of modernity ; Islamic revivalism ; Islamization of modernity ; rationality ; secularism ; Maulana Tariq Jamil ; Tablighi Jama’at ; Raiwind ; Deoband ; Islam in Pakistan ; ulama ; religious authority ; popular preachers ; Islamic televangelists ; da’wa ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: COVID-19 is the most prominent and rapidly evolving public health concern in the world currently. The gastrointestinal manifestations of COVID-19 are increasingly being recognized. SARS-CoV-2 infection has been associated with the occurrence of nausea, vomiting, and diarrhea. SARS-CoV-2 has also been causing pancreatic and hepatic injury. Emerging data have shown that COVID-19 patients continue to shed the virus into their stools, even when patients test negative for COVID-19 in pulmonary secretions. However, the epidemiology, pathogenesis, and treatment of SARS-CoV-2-related gastrointestinal manifestations are poorly understood. The pandemic has also had a significant impact on gastroenterologists, endoscopists, and other ancillary staff. Moreover, in the past, systematic respiratory virus syndrome (SARS) was shown to be transmitted by endoscopes, which is a big concern with COVID-19, as it shares many pathological features with SARS. The deferral of elective endoscopic procedures has negatively affected gastroenterologists. This Special Issue focuses on the current situation of this pandemic. It aims to provide insight into the gastrointestinal manifestations of COVID-19 and its effects on endoscopic procedures. I believe that this issue will be beneficial not only for gastroenterologists but also other healthcare workers around the world to recognize the often-ignored clinical gastrointestinal manifestations of COVID-19.
    Keywords: COVID-19 ; liver ; non-alcoholic steatohepatitis ; transient elastography ; mortality ; liver disease ; clinical manifestations ; SARS-CoV-2 ; gastroenterology ; hepatology ; endoscopy ; delivery of healthcare ; acute mesenteric ischemia ; thromboemboembolism ; endothelitis ; cytokines ; hypercoagulability ; inflammatory bowel disease ; gastrointestinal manifestations ; abdominal pain ; dyspnea ; clinical course ; upper gastrointestinal bleeding ; pandemic ; outcomes ; anxiety ; depression ; medication adherence ; severity of COVID-19 ; hospitalized patients ; risk factors ; SARS-CoV-2 infection ; gut dysbiosis ; microbiota ; gastrointestinal disorders ; intestinal inflammation ; ACE2 dysregulation ; gut microbiota ; enteric infection ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The reprint presents new approaches for bio- and immunosensors with nanodispersed labels and their optical registration. The use of nanoparticles as carriers and labels provides possibilities for simple measurements and reaching low detection limits. In this way, novel sensors obtain competitive advantages and good potential for implementation into diagnostic practice. The collected articles demonstrate the current state of developments and their most promising directions in the creation and characterization of such optical sensors.
    Keywords: mycotoxin ; food processing ; migration and transformation ; metabolites ; UPLC–MS/MS ; high-sensitive digital detection ; quantification ; functionalized gold nanoparticles ; microchips ; β-lactamases ; antibiotic-resistant bacteria ; luminescent composite particles ; carbon nanostructures ; luminescent carbon-based nanomaterials ; silica nanoparticles ; luminescence ; immunochromatography ; test strips ; RBD protein ; COVID-19 ; coronavirus ; microRNA detection ; polymerase-free isothermal amplification of nucleic acids ; mismatched catalytic hairpin assembly ; sulfonylureas ; broad-specificity ; antibody ; immunoassay ; adulteration ; functional foods ; thermoresponsive ; silver nanoparticles ; SERS ; 4-mercaptophenylboronic acid ; amphiphilic diblock copolymer ; poly(N,N-dimethylaminoethyl methacrylate) ; laser-induced aggregation ; plasmonic heating ; local laser exposure ; point-of-care test ; rapid diagnosis ; infectious diseases ; single-epitope sandwich ; double-epitope sandwich ; lumpy skin disease ; surface-enhanced Raman scattering (SERS) ; aptasensor ; SARS-CoV-2 virus ; surface-enhanced Raman spectroscopy ; influenza A virus ; influenza B virus ; detection ; machine learning ; catecholamines ; dopamine ; neurotransmitter ; resonance Raman spectroscopy ; surface-enhanced Raman spectroscopy (SERS) ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: Nurses represent the highest number of healthcare workers globally and have played a critical role in the COVID-19 pandemic. This reprint highlights the issues and challenges faced by nurses practicing in hospital and community settings during the COVID-19 pandemic. The manuscripts herein focus on nurses in various areas of practice, including nurse managers, highlighting the impact, experience, and reality of providing care during the crisis. Interventions and strategies to support practice environments and the mental health and wellbeing of the nursing workforce were identified. Evidence from these manuscripts shed light on how nurse leaders can provide relevant, coordinated, and consistent organizational and leadership support to better establish a safe and healthy work environment that protects and fosters the mental health and wellbeing of all nursing personnel. The pandemic exacerbated the already demanding quality of work environments for nurses, as well as their mental health and wellbeing, thereby inducing a global nursing shortage; therefore, improving these factors, which ultimately influence nurse retention, is critical. We trust that sharing the lived experiences of nurses during the COVID-19 pandemic can enable us to leverage their expertise in meeting the complex care needs of patients, including COVID-19 patients, while improving the care needed by nurses in their working environments, alongside preparing for future pandemic waves.
    Keywords: COVID-19 ; coronavirus 2019 ; ICU surge capacity ; nursing surge capacity and strategies ; pandemic ; medical humanities ; attitude ; compliance ; knowledge ; nursing students ; validation ; family ; bonding ; mother ; post-partum ; anxiety ; stress ; depression ; coping mechanism ; resilience ; spirituality ; family functioning ; healthcare providers ; vaccination ; Saudi Arabia ; attitudes ; acceptance ; advocate ; nursing ; qualitative research ; workforce ; coping strategies ; COVID-19 pandemic ; stressors ; coronavirus ; medical staff ; healthcare quality ; human resources ; primary care ; hospitals ; nursing home ; students ; clinical practice ; coping skills ; rural ; public health nursing ; changes ; clinical training ; review ; telehealth ; interprofessionalism ; usability ; coping behaviors ; salutogenesis ; risk factors ; nurses ; coronavirus disease (COVID-19) ; outbreak management ; seasonal farmworkers ; remote rural farms ; culturally and linguistically diverse ; student nurse educators ; e-assessment ; virtual practical examination ; health sciences education
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Discover the latest advancements in waste management and environmental sustainability with "Waste Treatment and Environmental Sustainability: Current Trends, Challenges, and Management Strategies". This comprehensive reprint features research and review articles that delve into the pressing issues of waste treatment and offer innovative solutions for a more sustainable future. Improper waste management poses significant risks to the environment and human health. Traditional methods have proven inadequate, driving the need for alternative approaches. This reprint explores sustainable practices such as bioremediation, phytoremediation, and green technologies that reduce waste generation and optimize resource utilization. The Special Issue included in the reprint presents 11 articles covering diverse topics such as predicting O3 levels, COVID-19's impact on household waste, reverse logistics, data analytics in waste management, and the role of biochar in phytoremediation. These articles provide valuable insights and directions for future research. "Waste Treatment and Environmental Sustainability" is an essential resource for researchers, practitioners, and policymakers passionate about waste management and environmental preservation. Explore the latest research findings and discover innovative strategies to create a cleaner, healthier, and more sustainable world.
    Keywords: sensor-based sorting ; robot sorting ; data analytics ; maturity model ; recycling ; waste treatment ; waste management ; phototrophic microorganisms ; cryoimmobilization ; poly(vinylalcohol) cryogel ; cryoconservation ; wastewater treatment ; microalgal inoculum ; long-term storage ; bioretention ; cumulative evaporation ; evaporation ; evaporation rate ; environmental factor ; sponge city ; municipal waste ; packaging ; logistics processes ; reverse logistics ; biochar ; remediation ; fertilizer ; contaminated soil ; heavy metals ; and soil fertility index ; air quality modeling ; ozone ; multiple linear regression ; artificial neural network ; municipal solid waste ; life cycle assessment ; global warming potential ; anaerobic digestion ; landfill ; NEV ; waste power batteries ; consumer environmental protection responsibility awareness ; recycling strategy ; reverse supply chain ; cyanide ; biodegradation ; Aerococcus viridans ; response surface methodology ; advanced oxidation process ; vinasse management ; ZnO ; ZnO-NPs ; effluent quality ; COVID-19 ; sustainability ; consumption ; behaviour ; Latin America ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-31
    Description: In this book, a series of modern multimodal monitoring techniques during general anesthesia are presented, with a focus on patient-oriented anesthesia based on the individual needs of each patient reflected in the degree of hypnosis, the nociception–antinociception balance, and neuromuscular transmission. Moreover, a series of secondary implications for hemodynamic status, post-anesthetic recovery, and patient satisfaction are highlighted.
    Keywords: iron deficiency ; anemia ; intravenous iron formulation ; perioperative period ; paediatric anaesthesia ; laryngeal mask ; gastric insufflation ; PEEP ; airway devices ; respiratory function ; false news ; COVID-19 ; frontline clinicians ; misinformation ; stress ; mental health ; anxiety ; insomnia ; hypnosis ; multimodal monitoring ; entropy ; qNOX ; qCON ; bispectral index ; surgical plethismographic index ; general anesthesia ; patient safety ; cardiac surgery ; enhanced recovery ; regional anesthesia ; ultrasound ; paravertebral blocks ; fascial plane blocks ; nociception level index ; POCD ; general emergency surgery ; anesthesia depth ; electroencefalography ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: In 2023, Economies celebrates its 10th anniversary. Thanks to the incredible support from all of you, the journal has developed into a well-respected academic journal. Economies has been included in several journal rankings, has a decent and growing number of submissions by well-known experts, and obtains very satisfactory citation scores given its young age. We acknowledge these achievements with a dedicated Special Issue. Therefore, researchers from all areas of economic research have been invited to submit their contributions to this Special Issue. The Special Issue is titled “Recent Topics in Economic Research” and covers a broad range of topics that are currently at the forefront of economics research and that are within Economies' scope. This includes original research papers as well as comprehensive review papers on topics of actual importance in economics.
    Keywords: DEA-approach ; non-parametric ; Tobit ; random-effect ; religion ; conventional ; time-series ; efficiency performance ; microfinance ; region ; gender ; female owned firms ; firm survival ; COVID-19 ; World Bank Enterprise surveys ; Brazil ; China ; import penetration ; informal labor markets ; wages ; online pharmacies ; brand name medicines ; price dynamics ; applied econometrics ; CO2 emissions ; energy consumption ; environmental degradation ; European region ; food production ; health problem ; macroeconomics ; obesity ; green economy ; tourism ; sustainable development ; hospitality ; energy ; Condorcet cycle ; Condorcet winner ; Condorcet paradox ; multidimensional issue space ; radial symmetry ; spatial modeling ; agent-based modelling ; bibliometric analysis ; network analysis ; conceptual structure ; social structure ; SMEs ; export performance ; innovation capabilities ; government institutional support ; active internationalization behavior ; reactive internationalization behavior ; Mozambique ; complexity theory ; economics ; public policy ; systematic review ; political budget cycles ; electoral cycles ; economic destabilization ; international trade ; environmental uncertainty ; financial information ; non-financial information ; organizational performance ; contingency theory ; survey ; Portugal ; remittances ; household saving behaviour ; household expenditure patterns ; propensity score matching ; Vietnam ; health ; expenditure ; poverty ; Knightian uncertainty ; multiplier preferences ; Ramsey planner ; social planner ; carbon tax ; capital tax ; ambiguity premium ; dynamic stochastic integrated general equilibrium (DSIGE) ; robust Arrow–Debreu asset prices ; global value chain ; textile and apparel ; developed and developing countries ; forward and backward participation ; explanatory factors ; Okun’s law ; employment ; unemployment ; US recessions ; jobless recovery ; job search ; business cycles ; Input–Output ; regionalization ; Hypothetical Extraction Method ; linkage analysis ; linguistic structures ; future time reference ; financial development ; discounting future ; income-related inequality of health ; health care utilization ; out-of-pocket payments ; decomposition analysis ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCM Development economics & emerging economies
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: This collection of articles provides an overview of the current and future methods for applying a personalized medicine approach to the diagnosis, management, and treatment of autism spectrum disorder.
    Keywords: fecal metabolites ; ASD ; microbiome ; gastrointestinal symptoms ; Fisher Discriminant Analysis ; digital biomarkers ; wearables ; time series analysis ; autism ; social dyads ; socio-motor parameters ; network connectivity ; non-linear complex dynamics ; stochastic analysis ; autism spectrum disorders ; copy number variants ; females ; Array-Comparative Genomic Hybridization (Array-CGH) ; autism spectrum disorder ; Ehlers-Danlos syndrome ; hypermobility spectrum disorders ; autonomic disorder ; mast cell activation syndrome ; genetic testing ; chromosomal microarray analysis ; whole exome sequencing ; whole genome sequencing ; clinical utility ; polygenic risk scores ; Temple Grandin ; biomarker ; omics ; precision medicine ; proteomics ; transcriptomics ; epigenetics ; metabolomics ; patient stratification ; mitochondria ; oxidative stress ; prenatal environment ; immune dysfunction ; immunoglobulin G ; intravenous immunoglobulin ; energy metabolism ; fatty acid oxidation ; acyl-carnitines ; resveratrol ; integrative ; model ; concomitant ; condition ; disorder ; autism spectrum disorder (ASD) ; genomics ; personalized treatment strategy ; single nucleotide polymorphisms ; clinical decision support tool ; ADHD ; PANDAS ; OCD ; anxiety ; folate receptor alpha ; folates ; pregnancy ; brain development ; fetal development ; cobalamin ; glutathione ; methylation ; methylcobalamin ; redox metabolism ; locked-in network syndrome ; resting-state functional magnetic resonance imaging ; temporal lobe epilepsy ; amygdala ; brain ; COVID-19 ; children ; cytokines ; flavonoids ; inflammation ; luteolin ; mast cells ; microglia ; SARS-CoV-2 ; stress ; nutraceuticals ; survey ; vitamins ; minerals ; B12 ; folinic acid ; quality of life ; parents ; intervention ; systematic review ; medical claims ; logistic regression analysis ; retrospective analysis ; associated risk ; monoamine neurotransmitters ; neurotransmitter deficiency ; cerebral folate deficiency ; folate receptor alpha autoantibodies ; leucovorin ; α-amylase ; cortisol ; heart rate variability ; neuromodulation ; sleep anxiety ; transdermal electrical neuromodulation ; neurostimulation ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: This Special Issue reprint consists of 10 research articles published in “Challenges in Work and Employment during the COVID-19 Pandemic. The authors, originating from six countries, have studied different professional and occupational groups during the pandemic. Their topics range from theoretical analysis of remote work to the experiences of self-leadership, and from new types of job demands to new support needs required to experience relatedness in the pandemic era.
    Keywords: dialogic development ; participatory action research ; remote and technology-driven workplace development ; well-being at work ; productivity ; renewal ; multi-actor assessment ; agency ; COVID-19 ; cultural sector ; precarious employment ; small agency ; inpatient ; substance abuse ; treatment ; professional ; Finland ; COVID-19 pandemic ; social work ; work communities ; social capital ; Nordic countries ; job demands ; job resources ; organizational support ; employee well-being ; work engagement ; exhaustion ; stress ; work from home ; worker identity ; work–life ; wellbeing ; labour process ; self-leadership ; psychological safety ; remote work ; multi-locational work ; well-being ; meaningfulness ; burnout ; work and organizational psychology ; occupational health ; academics ; universities ; South Africa ; work-from-home ; women engineer ; placement ; employment ; engineering education ; higher education employees ; enforced remote work ; self-determination theory ; basic psychological needs ; relatedness ; content analysis ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: In this reprint, we focus on health and wellbeing in the workforce within the context of the global COVID-19 pandemic, and the post-pandemic era. We begin by exploring the impacts of the pandemic on diverse occupational groups, considering the broader mental health impacts of the pandemic, reactions to national lockdowns and behavioural strategies to control the spread of the virus, such as social distancing and self-isolation, attitudes towards infection control and work presenteeism. Next, we explore the relationship between job factors, working conditions and psychological wellbeing of employees. The papers that follow examine changes in work patterns and locations, such as remote, hybrid, and on-site working, the impact of organizational climate on mental wellbeing, and organizational approaches to return-to-work after lockdown. Finally, we present innovative organizational- and individual-level pandemic mitigation interventions, including SARS-CoV-2 testing services and infection control approaches, digital mental health support, and COVID-19 Vaccine Education. This collection demonstrates the breadth of research on work, health and wellbeing, during and beyond the COVID-19 pandemic, covering workforce impacts and workforce interventions in various countries and settings. Learning from this research will help to build global preparedness for future pandemics and foster resilience for responding in times of crisis and uncertainty.
    Keywords: COVID-19 ; SARS-CoV-2 ; coronavirus ; mass testing ; social isolation ; social distancing ; mental health ; students ; focus groups ; qualitative ; emergency ; infectious disease ; organizational justice ; stress ; loneliness ; compassion fatigue ; meditation ; prayer ; insomnia ; perspective study ; frontline workers ; healthcare workers ; qualitative research ; trauma ; psychological support ; occupational health ; guidelines ; longitudinal study ; organisational justice ; anaesthetists ; restaurants ; occupational stress ; organizational climate ; environmental job stress ; wellness ; hospitality industry ; COVID‐19 ; pandemic ; psychological wellbeing ; digital ; healthcare ; workplace ; workforce ; staff ; semi-structured interviews ; COVID-19 disease ; Delta variant strain ; Nanjing Lukou International Airport ; airport cleaner ; essential worker ; infection risk ; occupational characteristics ; occupational health and safety vulnerability ; epidemic prevention and control ; burnout ; hospital health worker ; doctor ; nurse ; emotional exhaustion ; depersonalization ; personal accomplishment ; Maslach burnout inventory ; moral injury ; vaccine ; social care ; health education ; health protection ; paramedics ; mixed methods ; return to work ; quantitative job demands ; supervisor support ; fatigue management ; personal contribution in managing COVID-19 ; off-job crafting ; longitudinal ; employees ; DRAMMA ; prevention ; Germany ; Switzerland ; pre-post COVID-19 study ; remote work ; work engagement ; early care and education ; public health ; homelessness ; wellbeing ; organisational culture ; Scotland ; Maslach Burnout Inventory ; COVID-19 impact ; early childhood teachers ; well-being ; job demands ; teaching modality ; racial disparity ; undergraduate research experiences ; motivation ; sexual minority status ; faculty-mentored research ; higher education ; university ; essential workers ; health equity ; lockdown ; socio-occupational disparities ; worker protections ; effectiveness evaluation ; health and social services worker ; psychological health ; psychosocial work environment ; occupational determinants of stress ; self-rated health ; well-being at work ; church musician ; gender differences ; universities ; careers ; employability ; enforced telework ; home confinement ; job satisfaction ; coping strategies ; workplace health ; telecommuting ; health testing ; work stress ; interaction ; social capital ; health promotion ; university halls of residence ; regular epidemic prevention ; importance–performance analysis (IPA) ; childcare ; infectious disease control ; COVID-19 pandemic ; occupational safety and health ; infection control measures ; occupational SARS-CoV-2 risk of infection ; baseline data ; working conditions ; safety climate ; disaster preparedness ; presenteeism ; food system ; worker ; food insecurity ; fluorescent marker ; infection control ; dental clinics ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Earth observation (EO), remote sensing (RS), and geoinformation (GI) technologies play a critical role in the study of Svalbard's environment, providing insights into the region's changes and supporting decision-making processes. This reprint presents a comprehensive overview of the applications of EO and RS technologies in Svalbard, covering a wide range of topics related to the environment. It includes contributions from leading experts in the field, providing insights into the current state of the art and future directions for research. The reprint starts by introducing the status of EO and RS in Svalbard, providing a solid foundation for readers new to the field. It then delves into specific applications of these technologies, including the monitoring of glaciers, snow cover, and permafrost using ground-, space-, and air-based RS platforms. Overall, this book aims to provide a comprehensive overview of the applications of EO and RS technologies in Svalbard, highlighting their importance in understanding and addressing the challenges faced by the region. It will be a valuable resource for researchers, students, policymakers, and practitioners in the fields of environmental science, geography, and remote sensing.
    Keywords: snow cover ; remote sensing ; sea ice variability ; vegetation growth ; arctic climate change ; Arctic aerosol ; aerosol transport ; aged aerosol ; aerosol modification ; aerosol optical properties ; aerosol microphysical properties ; aerosol remote sensing ; microphysical inversion ; aerosol radiative effect ; Arctic radiative budget ; earth observation ; COVID-19 ; Svalbard ; earth system science ; SIOS ; polar regions ; snow modelling ; MODIS ; Sentinel-2 ; permafrost ; active layer ; InSAR ; time series ; ground displacement ; ground temperature ; displacement progression ; thaw progression ; Arctic ; NDVI ; time-series ; onset of growth ; classifier ; disturbance ; drone ; ecological monitoring ; GLCM ; herbivore ; random forest ; winter climate effect ; grubbing ; Arctic clouds ; cirrus clouds ; ice clouds ; lidar ; ocean eddies ; marginal ice zone ; sea ice ; SAR imaging ; Fram Strait ; Greenland Sea ; Hopen Island ; Arctic Ocean ; tidewater glaciers ; surface elevation changes ; glacier geometry ; structure-from-motion ; terrestrial laser scanning ; digital elevation model ; ICESat-2 ; laser altimetry ; kinematic GPS experiments ; glaciology ; surge glaciers ; svalbard ; density dimension algorithm for ice surfaces ; airborne validation of satellite data ; lake ice ; Sentinel-1 ; water temperature ; glacier facies ; atmospheric correction ; pansharpening ; WorldView-2 ; Ny-Ålesund ; Chandra–Bhaga basin ; target detection ; supervised classification ; Sentinel-1 and Sentinel-2 ; time series analysis ; snow melt ; tundra ; plant phenology ; ice cover ; Antarctic ; spectral reflectance ; hyperspectral data ; ocean colour ; coastal darkening ; SPM ; sediment plumes ; Arctic coast ; regional tuning ; coastal ecosystems ; land-ocean-interaction ; riverine inputs ; geographic object-based image analysis ; glacier surface facies ; surface facies of glaciers ; pixel-based image analysis ; atmospheric corrections ; image processing routines ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RG Geography
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: "Molecules at Play in Cancer" is a collection of 24 research articles on recent findings about some important molecules responsible for either cancer development and proliferation, or anti-cancer therapy. It covers a wide range of tissues and organs affected by cancer: adrenal glands, blood, breasts, muscles, ovaries, prostate, stomach, and testicles.
    Keywords: Agkistrodon ; leucine ; membrane ; phenylalanine ; venom peptides ; familial hyperaldosteronism type 3 ; KCNJ5 ; adrenal tumor ; β-catenin ; MALDI-IMS ; CYP11B2 ; PNU-74654 ; TNF receptor-1 ; apoptosis ; testicular cancer ; alveolar epithelial stem cells ; ACE2 ; SARS-CoV-2 ; COVID-19 ; RBD of spike glycoprotein ; metastatic microenvironment ; ovarian cancer ; exosomal microRNA ; biomarker ; early diagnosis ; BSG ; basigin ; CD147 ; MM ; multiple myeloma ; survival ; AP5M1 ; BAIAP2L1 ; CRISPR ; ENTPD2 ; master regulator ; LOC145474 ; MTOR ; PRRG1 ; VIM ; WFDC3 ; circulating tumor cells ; non-small-cell lung cancer ; single cell next generation sequencing ; nematode ; microenvironment ; cancer ; research ; ZEB2 ; prognosis ; immune cells ; cyclin D1 ; epidermal growth factor receptor (EGFR) ; stage I gastric cancer ; early gastric cancer ; node-negative gastric cancer ; B-cell maturation antigen (BCMA) ; soluble BCMA (sBCMA) ; multiple myeloma (MM) ; anti-BCMA CAR-T cell therapy ; INDEL ; genetic ancestry ; Amazon ; biomarkers ; KIRC ; GOT2 ; multi-omics ; epigenetics ; immune cell infiltration ; arsenic trioxide ; Parkin ; HeLa ; autophagy ; salivaomics ; breast cancer ; saliva ; molecular biological subtype ; HER2 status ; estrogen receptors ; progesterone receptors ; HPV DNA in breast ; nested PCR ; gastric cancer ; hsa-miR-942-3p ; AR ; MAPK/ERK signaling pathway ; HCC ; CTCs ; miRNAs ; proteomics ; fenbendazole ; microtubule polymerization ; self-administration ; EMT ; UQCRB ; ROS ; hypoxia ; HIF-1α ; deuterium-depleted water (DDW) ; deuterium-depleted yolk (DDyolk) ; anticancer drug development ; D/H ratio ; production of metabolic water ; ketogenic diet ; NEAT1 ; liver cancer cell line ; drug resistance ; SOD2 ; MAPK ; AKT ; rhabdomyosarcoma ; sarcoma ; mouse model ; Nf1 ; Ink4a/Arf ; vincristine ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19), posing a new challenge to the medical care of solid organ transplant (SOT) recipients. Due to the relatively small number of studies in SOT recipients suffering from COVID-19, the natural course of the SARS-CoV-2 infection, optimal treatment strategies including modification of immunosuppressive therapy and the prognosis in COVID-19 in these patients is incompletely understood. The current Special Issue aimed to fill some of the knowledge gaps and highlight some recent advances in the management of SOT patients during the pandemic. The call for manuscripts had been addressed to healthcare professionals involved in SOT patient care. We welcomed comprehensive reviews, original studies, interesting case series or case reports and commentaries relating to this topic.
    Keywords: SARS-CoV-2 ; coronavirus ; immunosuppression ; tacrolimus ; corticosteroids ; mycophenolate mofetil ; hyperinflammation ; cytokine storm ; pandemic ; transplantation ; Lung Transplantation ; COVID-19 ; Coronavirus ; norovirus ; treatment ; hypothesis ; cytokine storm syndrome ; FK506 ; cyclosporine ; myocarditis ; pediatric heart transplantation ; viral infection ; dexamethasone ; remdesivir ; hemodialysis ; transplant ; kidney ; PCR ; infection ; transplant recipients ; inflammation ; survival ; n/a ; solid-organ transplant ; unvaccinated ; lung transplantation ; fibrosis ; phenotype hypothesis ; lung transplant recipients ; immunocompromised ; breakthrough infections ; chronic lung allograft dysfunction ; community-acquired respiratory viral infection ; CLAD hypothesis ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint is an excellent collection of articles that deal with difficult-to-treat infections in the ICU environment. Multiresistant bacteria and fungi create severe treatment problems to the physician charged with their care. We hope that this book will help everyday dilemmas and add useful information on difficult topics.
    Keywords: Acinetobacter ; pandrug-resistant ; antimicrobial combinations ; synergy ; renal replacement therapy ; Monte Carlo simulation ; antibiotics ; pharmacokinetics ; pharmacodynamics ; microbiome ; probiotics ; intensive care unit ; dysbiosis ; ventilator-associated pneumonia ; extracorporeal membrane oxygenation ; ECMO ; critical illness ; antibiotic choices ; HAP ; VAP ; colonization ; antibiotic pressure ; bloodstream infection ; bacteraemia ; sepsis ; septic shock ; empirical ; probabilistic antibiotics ; source control ; de-escalation ; ICU ; intensive care ; antimicrobial stewardship ; COVID-19 ; procalcitonin ; C-reactive protein ; presepsin ; infection ; biomarker ; guided antimicrobial therapy ; APACHE II score ; bacteremia ; broth microdilution ; colistin ; colistin-resistant ; Gram-negative ; mortality ; SOFA score ; candidemia ; incidence ; epidemiology ; Candida species ; non-albicans Candida species ; fluconazole resistance ; critically ill ; beta-lactam antibiotics ; Acinetobacter baumannii ; antibiotic optimisation ; antibiotic stewardship (AMS) ; aspiration pneumonia ; hospital-acquired pneumonia (HAP) ; multidrug-resistance (MDR) ; non-fermentative Gram-negative bacilli (GNB) ; polymicrobial ; pneumonia resolution ; ventilator-associated pneumonia (VAP) ; carbapenem-resistant A. baumannii (CRAb) ; infection control ; antimicrobial agents ; carbapenems ; antibiotic resistance ; clinical pharmacy services ; Klebsiella pneumoniae ; Pseudomonas aeruginosa ; salvage treatment ; double carbapenem ; newer β-lactam-β-lactamase inhibitors ; cefiderocol ; eravacycline ; SARS-CoV-2 infection ; mechanical ventilation ; risk factors ; blood stream infection ; defined daily dose ; antibiotics utilization ; empiric ; n/a ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-06-23
    Description: Dual disorders, meaning the coexistence in the same individual of a substance use disorder and another mental disorder, have become an area of great interest in the fields of psychiatry and addiction and in health overall due to their high prevalence, clinical relevance and multicultural presence. This book includes a compilation of papers published between the end of 2021 and the beginning of 2023 focused on recent advances in dual disorders. The contributions present a broad look at various relevant aspects. Among them are the characterization of patients treated in different services, with special interest in the risk of overdoses, suicidal attempts and HIV, as well as the so-forgotten gender perspective and the impact of the COVID-19 pandemic on the attention of addiction centers. One of the first studies to consider the comorbidity of gambling disorders with substance use is also presented. The possible usefulness of explanatory models of machine learning for diagnosis and for performing chronobiological measurements that allow a more individualized treatment stand out among the novel contributions to the field of dual disorders. The aim of each of the contributions of this reprint is to be transferred for the benefit of clinical practice.
    Keywords: circadian rhythm ; dual disorders ; chronobiology ; substance use disorders ; schizophrenia ; major depressive disorder ; bipolar disorder ; distal skin temperature ; dual diagnosis ; consultation liaison service ; quality of life ; gender ; substance use disorder ; genetic polymorphisms ; neurocognition ; chronobiological therapy ; exposure to natural light ; clinical course ; alcohol-use disorders ; personality disorders ; externalizing ; network analysis ; antisocial personality disorder ; borderline personality disorder ; dual disorder ; mental disorders ; screening ; cocaine use disorder ; alcohol use disorder ; substance-related disorders ; treatment retention ; cannabis use disorder ; machine learning ; dual pathology ; COVID-19 ; care activity ; pandemic ; drug addiction ; mental health ; gambling disorder ; gambling-related offenses ; dropout ; relapse ; psychopathology ; personality ; substance use ; psychiatric comorbidity ; impulsivity ; co-occurring disorders ; suicidality ; overdose ; HIV ; patient navigation ; barriers to care ; social determinants of health ; syndemic framework ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: This book focuses on case studies and theoretical concepts on sustainable land-use management in agroforestry systems. Special attention is given to farmland management in the contexts of farmers’ investments, farmers’ economic and behavioral factors, and farmers’ perceptions of irrigation systems. Urban agriculture and its extensions (e.g., urban gardening and urban beekeeping) are also featured in this book, in addition to the ways in which these practices can contribute to biodiversity conservation goals. Additionally, a case study on the use of the ecosystem evaluation index is featured and provides scientific and practical bases for land protection. Lastly, a state-of-the-art review on land-use policy is included, providing insights into how agroforestry systems can be converted to other land uses to meet the current demands. Scientists, practitioners, and policymakers can make use of this book in designing sustainable agroforestry systems.
    Keywords: urban beekeeping ; regulations ; barrier ; setback ; 3D laser scanner ; remote sensing ; fence location ; organic agriculture ; environment-friendly agriculture ; regression tree ; attitude ; motivation ; satisfaction ; property rights ; ecological property rights ; forestry investment ; farmers’ behavior ; reservoir confluence area ; subjective wellbeing ; community perceptions ; urban gardening ; Indonesia ; COVID-19 ; evidence-based policymaking ; agricultural land ; forests ; consensus building ; Japan ; collective forest rights ; land tenure ; reform ; forestland investment ; public welfare ; forest land ; migration ; drought tolerant breeds ; adaptation ; relief grants ; policy intervention ; smallholder livestock farmers ; agricultural ; urban ; rice–fish farming ; biodiversity ; education ; experience ; museum ; land use ; land cover ; temporal and spatial change ; ecosystem assessment ; GIS ; northeast forest belt ; agroecosystem services ; alpine areas ; extensive livestock farming ; stakeholder participation ; focus group ; water resources ; water framework directive ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-11-30
    Description: Polyphenols are natural phytochemicals recognized as one of the largest and most widespread classes of plant constituents occurring throughout the plant kingdom. Over the years, polyphenols have attracted the attention of the scientific community due to their potential health-promoting effects. Owing to their several interesting properties, polyphenols have aroused considerable interest, shedding light on their chemistry, reactivity, biological properties and their beneficial effects on both plants and humans. As a result of these investigations, a huge number of research works have been reported on polyphenols. However, despite the voluminous literature studying polyphenols and their impact on human health, there are still many issues waiting to be explored in order to explain and elucidate the positive effects of polyphenols on human health. This Special Issue was intended to gather up-to-date knowledge related to the cutting-edge research in the broad scientific area of polyphenols, providing an opportunity to show the latest advances in the exploration of polyphenols and their health beneficial effects. The special issue was a great success with more than 50 published manuscripts covering various aspects related to polyphenols and their role in human health. We are confident that this Special Issue will be of great interest to the scientific community, and will contribute to the improvement of knowledge regarding the area of polyphenols, leading to a better understanding of their role in human health.
    Keywords: polyphenolic curcumin ; cisplatin ; combination therapy ; breast cancer ; apoptosis ; gemini surfactant nanoparticles ; Mucuna pruriens seed ; neuroprotective activity ; Parkinson’s disease ; anti-acetylcholinesterase activity ; L-dopa ; Mitrephora sirikitiae ; anti-inflammation ; lignans ; polyphenols ; mRNA expression ; cytokines ; gemini curcumin ; colorectal cancer ; RNA sequencing ; PPI network ; differentially expressed genes ; Ericaceae ; LC–DAD/ESI–MS ; phenolic compounds ; flavonoids ; antioxidant activity ; Artemia salina Leach ; resveratrol ; hexavalent chromium ; 8-hydroxydeoxyguanosine adduct repair ; endogenous antioxidant system ; antigenotoxic ; Opuntia sp. ; prickly pear ; inflammation ; ginseng leaf ; far-infrared irradiation ; ginsenosides ; antioxidants ; health benefits ; polysaccharides ; freeze-drying ; spray-drying ; antidiabetic ; Averrhoa carambola L. ; dihydrochalcone ; flavone glycosides ; obesity ; Oxalidaceae ; type 2 diabetes ; Alchemilla viridiflora Rothm. ; SARS-CoV-2 ; COVID-19 ; spike glycoprotein ; neuropilin-1 ; in vitro ; in silico ; Origanum compactum ; HPLC-PDA-ESI/MS ; antibacterial activity ; bioactive compounds ; nutraceuticals ; phenols ; pomegranate peels ; phytochemical ; wistin ; NADES ; total polyphenolic content ; enzyme inhibition ; functional food ; natural medicine ; Alzheimer cholinesterase inhibitors ; Maqui ; platelets ; phenolic compounds and cardiovascular ; phenolic acids ; sinapic acid ; ACE inhibition ; hypertension ; endothelial dysfunction ; Graminex pollen ; hydroalcoholic extract ; oxidative stress ; gene expression ; TRPV1 ; pterostilbene ; antioxidant ; bioavailability ; cancer ; diabetes ; Nrf2 ; Rosmarinus officinalis ; chemical analysis ; glioblastoma ; rhabdomyosarcoma ; red onion ; phytochemicals ; H9c2 rat cardiomyoblast ; primary human fibroblasts ; blood disorder ; haemoglobin ; natural product ; nutraceutical ; nutritional disease ; lichens ; neuroprotection ; cetrarioid clade ; grape polyphenols ; sarcopenia ; skeletal muscle ; clinical trial ; R. conduplicans ; lichen ; secondary metabolites ; DNA damage ; α-glucosidase inhibition ; adlay ; adlay testa ; antiglycation ; phenolic acid ; grape pomace ; anti-inflammatory ; curcumin ; poly(glycerol sebacate) ; nanoparticles ; drug delivery system ; human cervical cancer ; baicalein ; mangiferin ; quercetin ; diabetes mellitus ; peripheral artery disease ; cardiovascular diseases ; Cyperus esculentus ; tiger nut ; metabolomics ; UHPLC-ESI-QTOF-MS/MS ; foodomics ; scopolamine ; memory impairments ; phenol compounds ; polydatin ; 3-O-β-d-resveratrol-glucopyranoside ; cervical cancer ; lung cancer ; ovarian cancer ; nanosuspension ; antioxidant properties ; LPS-induced inflammation ; NO-scavenging activity ; mountain tea ; Lamiaceae ; iridoids ; phenylethanoids ; ultrasound-assisted extraction ; melittoside ; ajugoside ; verbascoside ; ferulic acid ; apoptosis and cell cycle arrest ; anti-angiogenesis ; anti-metastasis ; synergism ; Cymbopogon schoenanthus ; hyaluronidase ; acetylcholinesterase ; neurodegeneration ; skin ; hair ; human health ; immobilized PTP1B ; drug screening ; cell surface display ; salvianolic acid B ; traditional Chinese medicine ; Salicornia ; extraction technologies ; agro-industrial by-products ; biological activity ; circular economy ; health effects ; re-integration ; waste management ; blood orange peels ; infrared-assisted extraction ; optimization ; Aflatoxin B1 ; Achillea millefolium ; bioaccessibility ; Caco-2 absorption ; in vitro digestion ; sterol regulatory element-binding protein 1 ; human oral squamous cell carcinoma ; autophagy ; epidermal fatty acid-binding protein ; lentil hull ; enzymatic hydrolysis ; microwave-assisted extraction ; oligosaccharides ; Alocasia gigantea ; hepatocellular carcinoma ; histopathology ; UHPLC–DAD–ESI–MS/MS ; Salvianolic acid B ; matrix metalloproteinase 9 ; gelatinase B ; MDA-MB-231 human breast cancer cells ; TIMP-1 ; agri-food wastes ; sustainability ; polyphenols bioavailability ; polyphenols activity ; cosmeceuticals ; nano-delivery ; health ; Lithocarpus litseifolius ; trilobatin ; phloridzin ; phloretin ; metabolic pathway ; bioactivity ; honey ; functional beverage ; characterization ; alcoholic beverage ; fermented beverage ; functional foods ; beneficial effects ; biological treatment ; bioreactors ; water ; aerobic granular sludge ; conventional active ted sludge ; biofilter ; photobioreactor ; membrane bioreactor ; bio-electrochemical systems ; chitosan ; Indian borage ; biotic elicitor ; insect-based foods ; Folin–Ciocalteu method ; phenols and flavonoids ; polyphenols bioactivity ; cereal ; pre-harvest sprouting ; antiradical capacity ; antitumor activity ; bee products ; phenylamides ; multivariate statistical analysis ; Juniperus sabina ; cupressuflavone ; intranasal ; pharmacokinetic ; motor coordination ; oregano ; box–behnken ; phenolics ; HPLC-PDA analysis ; UPLC-Q-TOF MS ; olive pomace ; PBMC ; immune gene expression ; HPLC-DAD ; metabolome ; phenolic bioaccessibility ; propolis ; total phenolic compounds ; antioxidant capacity ; UHPLC-DAD-ESI-MS ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: With the development of computer technology and communication technology, various industries have collected a large amount of data in different forms, so-called big data. How to obtain valuable knowledge from these data is a very challenging task. Machine learning is such a direct and effective method for big data analytics. In recent years, a variety of advanced machine learning technologies have emerged, and they continue to play important roles in the era of big data. Considering advanced machine learning and big data together, we have selected a series of relevant works in this Special Issue to showcase the latest research advancements in this field. Specifically, a total of thirty-three articles are included in this Special Issue, which can be roughly categorized into six groups: time series analysis, evolutionary computation, pattern recognition, computer vision, image encryption, and others.
    Keywords: energy storage ; model predictive control ; peak shaving and frequency regulation ; output optimization ; global optimization ; meta-heuristic ; support vector machine swarm intelligence ; hyperspectral image classification ; CNN ; ELM ; PSO ; deep feature ; butterfly optimization algorithm ; random replacement ; crisscross search ; overseas Chinese associations ; support vector machine ; short-term traffic-flow forecasting ; bagging model ; stacking model ; ridge regression ; error coefficient ; least squares method ; support vector machines ; principal component analysis ; quick access recorder ; mean absolute error ; high-plateau flight ; event extraction ; event type ; event trigger words ; stock announcement news ; stock return ; traffic flow forecasting ; long short-term memory network ; graph convolutional network ; target detection ; infrared ; deep learning ; YOLOv5 algorithm ; design science research ; performance analysis ; machine learning ; classification algorithms ; clustering algorithms ; pilot abnormal behavior ; behavior detection ; YOLOv4 algorithm ; CBAM ; flight safety ; fault diagnosis ; variational mode decomposition ; composite multi-scale dispersion entropy ; particle swarm optimization ; deep belief network ; CBCFI ; combined prediction model ; ARMA ; GM ; GA ; BP ; hierarchical clustering ; Jaccard distance ; membership grade ; community clustering ; lightweight neural networks ; attentional mechanisms ; Hemerocallis citrina Baroni ; maturity detection ; cloud ; digital archives ; confidentiality management ; information system ; emotion-cause pair extraction ; heterogeneous graph ; graph attention network ; hierarchical model ; spatial-temporal systems ; neural networks ; information systems ; forecasting ; time series ; coupled map lattice ; polymorphic mapping ; color image ; hash function ; pixel level ; differential evolution ; capacitated vehicle routing planning ; saving mileage ; gravity search ; object detection ; computer vision ; border patrol ; COVID-19 ; warning system ; PROPHET ; health ; quantum dynamics ; neural architecture search ; image classification ; swarm intelligence ; whale optimization algorithm ; extreme learning machine ; talent stability prediction ; adversarial attacks ; document classification ; NLP ; convolutional neural networks ; disease classification ; generative adversarial network ; tomato leaf ; multi-strategy ; dual-update strategy ; mean-semivariance model ; portfolio optimization ; DNA computing ; DNA sequences design ; improved matrix particle swarm optimization algorithm (IMPSO) ; opposition-based learning ; signal-to-noise ratio distance ; time series classification ; complementary ensemble empirical mode decomposition (CEEMD) ; MultiRocket ; feature selection ; hybrid model ; multi-behavior recommendation ; sequential recommendation ; graph neural network ; embedding propagation ; 1D quadratic chaotic system ; image encryption ; splicing model ; DNA coding ; BaaS system ; blockchain consensus algorithm ; KNN ; service level agreement ; transaction priority ; data stream mining ; forex ; online learning ; adaptive learning ; incremental learning ; sliding window ; concept drift ; financial time series forecasting ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-23
    Description: This Special Issue reprint consists of 10 research articles published in “Challenges in Work and Employment during the COVID-19 Pandemic. The authors, originating from six countries, have studied different professional and occupational groups during the pandemic. Their topics range from theoretical analysis of remote work to the experiences of self-leadership, and from new types of job demands to new support needs required to experience relatedness in the pandemic era.
    Keywords: dialogic development ; participatory action research ; remote and technology-driven workplace development ; well-being at work ; productivity ; renewal ; multi-actor assessment ; agency ; COVID-19 ; cultural sector ; precarious employment ; small agency ; inpatient ; substance abuse ; treatment ; professional ; Finland ; COVID-19 pandemic ; social work ; work communities ; social capital ; Nordic countries ; job demands ; job resources ; organizational support ; employee well-being ; work engagement ; exhaustion ; stress ; work from home ; worker identity ; work–life ; wellbeing ; labour process ; self-leadership ; psychological safety ; remote work ; multi-locational work ; well-being ; meaningfulness ; burnout ; work and organizational psychology ; occupational health ; academics ; universities ; South Africa ; work-from-home ; women engineer ; placement ; employment ; engineering education ; higher education employees ; enforced remote work ; self-determination theory ; basic psychological needs ; relatedness ; content analysis ; n/a ; thema EDItEUR::A The Arts::AT Performing arts::ATF Films, cinema ; thema EDItEUR::A The Arts::AT Performing arts::ATJ Television
    Language: English
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  • 81
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Air pollution is a mixture of particles and gases, which can reach unsafe concentrations for human health, the environment, vegetation, and materials. It has become one of the main sustainability issues and a concerning topic in atmospheric science. According to the World Health Organization (WHO), 90% of the world’s population lives in highly polluted environments, and about 7 million premature deaths are caused yearly by outdoor and indoor air pollution. The combination of fast-growing populations, transport, fossil fuels, and biomass burning leads to pollution levels being especially high in some urban areas. Agriculture and natural phenomena are also important sources of pollution, underscoring the multi-faceted and transboundary nature of air pollution. The monitoring and understanding of the temporal and spatial behaviours of air pollutant concentrations are essential for both the implementation of air quality policies and the definition of effective measures to mitigate air pollution and its effects. Quantifying and monitoring exposure to air pollution in terms of public health is also a critical component in policy discussion. This reprint presents recent research activities concerning the characterization of air pollution and the applied modelling approaches.
    Keywords: carbon trading ; green innovation efficiency ; propensity score matching ; difference in differences model ; meteorology ; WRF ; air quality ; AERMOD ; source apportionment ; environmental impact assessment ; condensable particulate matter ; air quality model ; PM2.5 ; air pollution ; particulate matter ; microplastics ; non-exhaust emissions ; NORTRIP ; air pollution transmission ; indoor–outdoor relation ; urban canyon ; computational fluid dynamics ; factors of transmission ; cluster analysis ; meteorological influence ; Multiple linear regression ; NOx influence ; Pearson’s correlation ; rural trends ; surface ozone ; mashrabiya ; total volatile organic compounds (TVOC) ; formaldehyde (HCHO) ; retention period ; hot desert climate ; occupational exposure ; Bayesian spline model ; time-series ; public transport ; inhalation ; air quality plans ; PM2.5 episodes ; air pollution policy ; NO2 concentrations ; diff-in-diff-regression ; urban agglomeration (UA) ; regional difference ; distribution dynamics ; convergence ; Utah ; environmental history ; national ambient air quality standards ; machine learning ; atmospheric pollution ; self-organizing maps ; Salvador-BA ; COVID-19 ; Tehran ; AQI ; landscape architecture ; urban green space ; human thermal comfort ; spatial differentiation ; evidence-based design ; dispersion model ; health risk assessment ; indoor air quality ; cook stove ; biomass burning ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQK Pollution control
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  • 82
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-07-14
    Description: Coronavirus disease 2019 (COVID-19) is a new respiratory disease caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that caused a global pandemic. COVID-19 patients often develop acute respiratory distress syndrome (ARDS), which involves acute and lethal respiratory failure. In a meta-analysis, the median incidence of ARDS in COVID-19 patients was found to be 35 (2-79)%, while the mortality rate in COVID-19-associated ARDS patients was found to be 39 (12.5-73.1)% (Hasan, et al. Expert Rev Repoir Med. 2020; 14: 1149). As of 12 December 2021, 270,373,764 cases had been confirmed as COVID-19 and 5,321,321 cases had resulted in death, according to the World Health Organization webpage. Various symptoms such as persistent fatigue, myalgia, and insomnia can persist after recovery from COVID-19; these symptoms are called “long COVID-19”. Patients with COVID-19 who survive but develop pulmonary fibrosis may experience persistent dyspnea upon exertion, a decrease in pulmonary function, and/or a radiological abnormal shadow. Antifibrotic drugs including nintedanib and pirfenidone are candidate drugs for the treatment of pulmonary fibrosis due to COVID-19; randomized controlled trials are ongoing. However, there are limited studies about respiratory disease caused by COVID-19. Given the clinical significance of this topic and its impact on clinical practice and public health, Medicina have published a Special Issue entitled “Respiratory Disease in the COVID-19 Era” with the aim of gathering accurate and up-to-date scientific information of this topic.
    Keywords: heart rate ; COVID-19 ; pulmonary rehabilitation ; COVID-19 vaccines ; adult ; pneumonia ; risk ; SARS-CoV-2 ; Pneumocystis jirovecii pneumonia ; interstitial pneumonia ; steroids ; immunosuppressive drugs ; spontaneous pneumomediastinum ; subcutaneous emphysema ; therapeutic plasma exchange ; ARDS ; inflammatory markers ; survival ; immunocompromised host ; Bruton’s tyrosine kinase ; persistent infection ; pulmonary paragonimiasis ; Paragonimus westermani ; post-COVID-19 condition ; delayed diagnosis ; case cluster ; Bamlanivimab ; Etesevimab ; lung ultrasound ; RT-qPCR ; HRCT ; diabetes mellitus ; computed tomographic severity score ; immunocompromised ; coronavirus disease 2019 ; hydroxychloroquine ; severe acute respiratory syndrome ; n/a ; diaphragm ; thoracic mobilization ; respiratory function ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine::MBNS Epidemiology & medical statistics
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  • 83
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-05-11
    Description: It is a great pleasure to provide you this Special Issue of Nutrients related to the 5th International Conference “Vitamin D—Minimum, Maximum, Optimum”, under the auspices of the European Vitamin D Association (EVIDAS). The conference and the forthcoming papers serve as an international forum for the presentation and discussion of current basic and clinical research in the field of vitamin D. Organizing this subsequent Special Issue was truly challenging, given that vitamin D has recently been shown by prestigious medical journals to be an epiphenomenon that coincides with diseases, and that the correction of vitamin D deficits has limited clinical meaning. On the other hand, it was recognized that vitamin D deficiency is a global health problem with potential negative consequences on health, welfare, and morbidity during growth and adulthood, therefore influencing healthcare services worldwide. Thus, due to mutually exclusive conclusions, it was essential to discuss and share scientific reports and evidence demonstrating both the benefits and lack thereof in relation to human health. Prof. Dr. Pawel Pludowski Guest Editor
    Keywords: vitamin D ; calcidiol ; supplementation ; COVID-19 ; RCT ; clinical trial ; cholecalciferol ; randomized controlled trial ; epidemiology ; mortality ; infections ; nutrition ; 25-hydroxyvitamin D ; infection ; study design ; clinical trials ; Alzheimer’s disease ; cancer ; cardiovascular disease ; diabetes ; hypertension ; Mendelian randomization ; vitamin D status ; prevalence ; female migrants ; United Arab Emirates ; blood pressure ; cardiovascular risk ; vitamin D deficiency ; recommendations ; guidelines ; treatment ; juvenile idiopathic arthritis ; calcium/phosphate metabolism ; methotrexate ; children ; inflammation ; pneumonia ; SARS-CoV-2 ; CYP24A1 ; pregnancy ; hypercalcemia ; fertility ; lactation ; intoxication ; idiopathic infantile hypercalcemia ; 25(OH)D ; B cell subsets ; inflammatory markers ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
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  • 84
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: Chapter 1. Theoretical Principles of a New Media and Technology Education. Description: Theoretical approach to the problems addressed in the book. Chapter 2. Outside Training of Spanish University Students of Education for the Didactic Application of Cinema: Formal, Non-Formal, and Informal Perspectives.Description: Study on the effect of training on perceptions of the educational potential of cinema in universities as a teaching instrument.Chapter 3. The Development of the Competency of “Cultural Awareness and Expressions” Using Movie-Induced Tourism as a Didactic Resource. Description: Analysis of the role of film tourism in the development of skills in the cultural sphere.Chapter 4. Assessment of Digital Competencies of University Faculty and Their Conditioning Factors: Case Study in a Technological Adoption Context.Description: Ex post facto methodology for the study of the development of digital competences among university teaching staff. Chapter 5. Tourism and ICT. Bibliometric Study on Digital Literacy in Higher Education.Description: Literature review on digital literacy and tourism in universities. Chapter 6. Portuguese Primary and Secondary Education in Times of COVID-19 Pandemic: An Exploratory Study on Teacher Training and Challenges.Description: Exploratory analysis of ICT teacher training in Portuguese primary and secondary education during the COVID-19 pandemic.
    Keywords: bibliometric ; digital literacy ; digital education ; educational technology ; higher education ; ICT ; tourism ; media education ; movie-induced tourism ; didactic resource ; educational activities ; competence development ; teachers ; training ; technologies ; COVID-19 ; pedagogy ; challenges ; digital competences ; technology adoption ; teacher training ; digital skills ; cinema ; audiovisual media ; preservice teacher training ; university education ; formal education ; non-formal education ; informal education ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JN Education
    Language: English
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  • 85
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19), posing a new challenge to the medical care of solid organ transplant (SOT) recipients. Due to the relatively small number of studies in SOT recipients suffering from COVID-19, the natural course of the SARS-CoV-2 infection, optimal treatment strategies including modification of immunosuppressive therapy and the prognosis in COVID-19 in these patients is incompletely understood. The current Special Issue aimed to fill some of the knowledge gaps and highlight some recent advances in the management of SOT patients during the pandemic. The call for manuscripts had been addressed to healthcare professionals involved in SOT patient care. We welcomed comprehensive reviews, original studies, interesting case series or case reports and commentaries relating to this topic.
    Keywords: SARS-CoV-2 ; coronavirus ; immunosuppression ; tacrolimus ; corticosteroids ; mycophenolate mofetil ; hyperinflammation ; cytokine storm ; pandemic ; transplantation ; Lung Transplantation ; COVID-19 ; Coronavirus ; norovirus ; treatment ; hypothesis ; cytokine storm syndrome ; FK506 ; cyclosporine ; myocarditis ; pediatric heart transplantation ; viral infection ; dexamethasone ; remdesivir ; hemodialysis ; transplant ; kidney ; PCR ; infection ; transplant recipients ; inflammation ; survival ; n/a ; solid-organ transplant ; unvaccinated ; lung transplantation ; fibrosis ; phenotype hypothesis ; lung transplant recipients ; immunocompromised ; breakthrough infections ; chronic lung allograft dysfunction ; community-acquired respiratory viral infection ; CLAD hypothesis ; bic Book Industry Communication::M Medicine
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  • 86
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-05-11
    Description: The aim of the reprint was to provide readers with updated research findings on the psychological and psychiatric consequences of the pandemic. The wide scope of the reprint reflects the complexity of the impact of the COVID-19 pandemic on mental health. The focus of the studies ranges from the psychological consequences of social distancing and the closure of schools to the neurological consequences of the viral infection, and from the stressful impact of an increased workload on frontline health workers to the unmet needs of special populations such as pregnant women, veterans and patients with neurodevelopmental disorders. Thanks to its richness in content and worldwide perspectives (contributors were from Canada, Croatia, Greece, India, Israel, Italy, Pakistan, the Philippines, Poland, Spain, and the USA), the reprint is a valuable source of information to researchers and clinicians interested in the mental health implications of the COVID-19 pandemic.
    Keywords: COVID-19 ; adolescents ; concerns ; activities ; frustration ; SARS-CoV-2 ; coronavirus pandemic ; anxiety ; depression ; mental health ; psychological empowerment ; fear of COVID-19 ; collaborative crafting ; job crafting ; emotional disorders ; psychological detachment ; suicidal behavior ; first emergency care ; multicentric ; Lombardy ; depressive symptoms ; nurses ; medical doctors ; frontline ; pooled prevalence ; brain ; neurotropism ; cognitive ; prevention ; diagnosis ; fear ; healthcare workers ; neuroticism ; insecure attachment ; autism ; telehealth ; behavioral skills training ; parent training ; psychological distress ; pregnancy ; disaster ; telemedicine ; theory–practice gap ; stress ; trauma ; coronavirus infections ; health personnel ; emergency medical services ; psychological stress ; self-efficacy ; incidence ; mixed effects model ; Random Effects/Expectation Maximization (RE-EM) Tree ; PTSD ; war-related stress ; pandemic-related stress ; treatment-seeking ; college ; students ; DASS21 ; pandemic ; gender ; coronavirus disease 2019 (COVID-19) ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ; neuropsychiatry ; neurodegenerative diseases ; neurodevelopmental diseases ; coronavirus ; family ; fetal brain function ; maternal stress ; COVID-19 pandemic ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBP Health systems & services::MBPK Mental health services
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  • 87
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: As we know, a large amount of research confirms that physical activity (PA), physical fitness (PF), and motor competence (MC) are associated with health benefits in individuals of all ages. Achieving a sufficient level of PA and PF will consequently further contribute to better health-related biomarkers. Moreover, holding a good MC allows better participation in PA and exercise in life, promoting greater physical literacy.It is true that the measurement of PA in children and young people is subject to several conditioning factors which threaten validity and reliability. Additionally, it is good to remember that the World Health Organization guidelines on PA and sedentary behaviour for children recommend: (1) 180 min of PA (at any intensity) for two-year old children; (2) 180 min of PA, of which 60 min is moderate-to-vigorous physical activity (MVPA), for 3- to 4-year-old children; and (3) at least 60 min of MVPA for children and adolescents from 5 to 17 years old.Therefore, understanding and developing strategies to promote PA behavior is now more important than in the past, because it is essential to improve fitness levels and MC in early ages. These strategies should cover all generations, children and youth, adults and the elderly, equally, because negative outcomes are visible in individuals of all ages.In this Special Issue, we show contributions that describe and list the link, monitoring and promotion between PA, PF, and MC.
    Keywords: flat foot ; subtalar flexibility ; plantar arch index ; orthoses ; the International Fitness Scale (IFIS) ; reliability ; children ; adolescents ; Chinese ; handball ; motor capacity ; psychological characteristics ; junior players ; software creation ; adolescent ; exercise ; sport pedagogy ; physical education ; Mediterranean diet ; emotional intelligence ; physical activity ; body mass index ; verbal encouragement ; Hoff circuit ; enjoyment ; mood ; performance ; COVID-19 ; lockdown ; motor learning ; motor skills ; balance ; sedentary time ; sedentary pattern ; cardiorespiratory fitness ; ASD ; postural control ; rehabilitation ; combat sports ; physical fitness ; mental health ; PFI ; children and adolescents ; association analysis ; cross-sectional survey ; space–temporal orientation ; general intelligence ; psychomotricity ; specific intervention ; youth ; sprint ; jump ; YBT ; FMS ; motor competence ; health ; monitoring and promoting ; sport ; sedentary behavior ; obesity ; well-being ; active free time ; factors affecting physical fitness ; passive free time ; Zuchora test ; ActiGraph accelerometer ; machine learning ; walking ; early childhood ; cerebral palsy ; therapy activation ; programme ; excess weight ; urban environment ; sedentary behaviour ; socio-ecological mode ; human development ; motor development ; motor test ; motor performance ; lifespan ; football ; sports medicine ; physical exercise ; physical conditioning ; child ; body image ; self-perception ; body shape questionnaire
    Language: English
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  • 88
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-06-23
    Description: Digital health, virtual assistance, and telemedicine are terms often used interchangeably to refer to remote medical assistance, monitoring and care. Several studies and insights have developed these issues, analyzing the advantages and disadvantages and successes and failures and offering reflections on the implications and issues of these technologies in the health domain. The results of these investigations are affecting the redesign of hospital and outpatient management based on digital innovation using eHealth and mHealth. During the COVID-19 pandemic, this approach made it possible to offer assistance and continue care at home, protecting patients, preserving health workers, limiting the spread of the virus, and reducing the need for hospitalization. This reprint contains contributions dealing with the development of DH during the COVID-19 pandemic. The contributions are from various experts in different fields regarding the application of digital health, which, in some cases is also integrated with artificial intelligence, including digital contact tracing, mHealth, virtual reality, mental health, physiology, and rehabilitation.
    Keywords: n/a ; digital contact tracing ; IMMUNI app ; COVID-19 ; students ; digital care visit ; online consultation ; medical staff ; healthcare personnel ; user experience ; magnetic resonance imaging (MRI) ; brain tumor ; machine learning ; digital health ; e-health ; pandemic ; physical activity ; performance evaluation ; eHealth ; self-care ; chronic diseases ; mental health ; mindfulness ; mobile health ; social isolation ; mental stress ; feature selection ; artificial intelligence ; human health ; lock down ; normative activation model ; COVID-19 prevention ; prevention intention ; IoT ; obesity ; classification ; regression ; real-time system ; COVID-19 pandemic ; contact tracing ; CNN ; chest X-ray images ; hybrid learning ; computer-aided diagnosis ; remote psychotherapy ; psychotherapy via telephone ; psychotherapy via videoconferencing ; tele-health ; e-mental-health ; psychotherapy ; qualitative psychotherapy research ; mixed-methods psychotherapy research ; exergaming ; breast neoplasms ; physical function ; telehealth ; (d)health literacy ; health literacy ; health intervention ; health strategy ; medical data ; medical imaging ; data classification ; image detection ; YOLOv4 ; logistic regression ; AI ; deep learning ; chatbot ; health ; health domain ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBP Health systems & services::MBPK Mental health services
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  • 89
    Publication Date: 2024-03-28
    Description: This reprint is dedicated to Professor Delfim F. M. Torres for his 50th birthday. Professor Delfim F. M. Torres is a recognized researcher, particularly in the calculus of variations, optimal control, and mathematical biology. In this reprint, several studies in his research fields are presented.
    Keywords: calculus of variations ; non-Newtonian calculus ; multiplicative integral functionals ; multiplicative Euler–Lagrange equations ; admissible positive functions ; epidemiology ; mathematical modeling ; fractional calculus ; equilibrium ; stability ; fractional (p, q)-integral ; fractional (p, q)-difference ; periodic boundary value problems ; existence ; coronavirus disease 2019 (COVID-19) ; ABC derivative ; hybrid method ; existence analysis ; semi-analytical solution ; fractional derivatives ; distributional derivatives ; Sobolev spaces ; bounded variation functions ; embeddings ; compactness ; Abel equation ; optimal control ; maximum principle ; mixed constraints ; Physics Informed Neural Networks ; data analysis ; COVID-19 ; vaccination ; basic reproduction number ; Lyapunov function ; weighted generalized fractional calculus ; integration by parts formula ; Euler–Lagrange equation ; quantum mechanics ; fractional differential equations ; boundary value problems ; Kolmogorov–Riesz theorem ; fixed point theorems ; Nemytskii operator ; approximation solution ; fuzzy number ; fuzzy fractional order derivative ; coronavirus infection system ; Adomian decomposition method ; convex surfaces ; surface area measure of a convex body ; Newton’s problem of minimal resistance ; measles ; mathematical model ; global sensitivity analysis ; partial rank correlation coefficient (PRCC) ; fractional derivative ; Caputo derivative ; Ulam–Hyers stability ; fractional control systems ; neutral evolution systems ; controllability ; minimum energy ; Banach fixed point theorem ; population dynamics ; vertical transmission ; epidemic fear ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science
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  • 90
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: Maritime transport contributes to over 80% of global trading volumes. As such, marine policy has received a large amount of attention from industrial practitioners, researchers, policymakers, and the local community. In general, marine policy covers a wide-ranging area, including governance, international relations, economics, environments, and operations, amongst others. To a certain extent, marine policy fosters the sustainable development of the maritime industry. There has been a wide range of research in different disciplines of marine policy.The purpose of this book is to publish the most intriguing research with respect to the above subjects and to provide a rapid turn-around time regarding reviewing and publishing, as well as to disseminate articles freely for research, teaching, and reference purposes. Furthermore, the book aims to keep readers up to date with the latest developments and research in maritime affairs.
    Keywords: crisis management ; maritime management ; circular letter ; corpus linguistics ; coevolution ; blockchain (BC) ; adoption ; challenges ; developing environments ; Chinese cruisers ; arctic region ; travel constraint ; preference ; behavioral intention ; vessel deployment ; de-hubbing ; transhipment ; port development ; container demand ; liner shipping ; uncertainties ; ship schedules ; schedule recovery ; recovery strategies ; literature survey ; maritime container shipping (MCS) ; network analysis ; Suez Canal (SC) ; weighted network ; graph theory ; 1970s ; liner service (LS) ; disruption simulation ; Maritime Silk Road ; shipping network structure resilience ; dominant port ; vulnerable port ; crisis response ; corporate social responsibility ; container shipping ; text analysis ; COVID-19 ; ferry ; navigation ; safety ; risk ; fuzzy AHP ; coastal management ; fishing areas ; spatial planning ; coastal environmental ; coastal geopolitics ; blue economy ; bibliometrics ; export promotion programs ; export competitiveness ; export performance ; marine transportation ; craft products ; niche differentiation strategy ; craft product ; ship ; transport ; English ; engineer ; IMO ; carbon neutral ; marine fishery ; carbon emission ; carbon sink ; net carbon emission ; LMDI ; maritime industry ; safety management ; ISM Code ; safety supervision ; shipboard safety ; n/a
    Language: English
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  • 91
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: This reprint "Clinical Features of COVID-19 in Elderly Patients" is a crucial resource dedicated to the medical challenges posed by the pandemic, with a specific focus on its impact on elderly people. Given their vulnerability, understanding the clinical aspects of COVID-19 in this demographic is paramount. This reprint compiles a wide array of studies and current knowledge tailored to address the unique challenges faced by elderly people during the pandemic. It surpasses literature reviews, offering critical analysis and in-depth discussions. Its primary goal is to encourage critical analyses and discussions about the clinical characteristics of COVID-19 in elderly people. Targeted towards medical professionals, researchers, and healthcare practitioners, it aids in the development of tailored treatment approaches and care protocols. As the COVID-19 pandemic persists, this reprint remains essential for those dedicated to combating the virus, enhancing elderly patients’ care, and promoting public health.
    Keywords: COVID-19 ; SARS-CoV-2 ; clinical features ; elderly
    Language: English
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  • 92
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: This book explores sustainable urban development, addressing the challenges and opportunities encountered in the 21st century. It addresses topics such as resilience, blockchain architecture, and green roofs, offering insights into urban challenges and opportunities. The research provides innovative strategies and best practices for sustainable, equitable, and resilient urban communities. The collection emphasizes stakeholder integration, community engagement, and the importance of addressing specific challenges faced by vulnerable populations. As a valuable resource for researchers, practitioners, policymakers, and students, this publication aims to foster informed conversations about the future of urban planning and design, and inspire further research and dialogue on sustainable urban development, paving the way for more sustainable urban communities worldwide.
    Keywords: green buildings ; occupant well-being ; healthy buildings ; occupant-orientation ; indoor environment conditions ; residential property ; public transportation ; metro ; rail ; flat ; resource-based city ; green land use efficiency (GLUE) ; carbon emissions ; the Yellow River Basin (YRB) ; multimodal data ; attention mechanisms ; data fusion ; urban planning ; energy consumption ; building energy ; spatial autocorrelation ; multiscale geographically weighted regression (MGWR) ; prefabricated construction ; digital green innovation management ; venture capital ; project partners ; transfer of development rights (TDR) ; land registry ; land management ; preservation of buildings ; historic buildings ; development restriction ; development loss ; floor area ; Turkey ; sustainable urban planning ; digital legislation and policy ; rural digitalization reform ; digital technology ; energy conservation ; extraversion ; green hotel ; past behaviour ; personality traits ; pro-environmental management ; city–county consolidation ; market competition ; earnings management ; urbanization development ; sustainable urban development ; urban resilience ; influencing factors ; Chengdu–Chongqing urban agglomeration ; urban rail transit (URT) ; PPP ; value creation ; grounded theory ; smart home ; secure architecture ; blockchain ; storage efficiency ; IoT ; climate change ; GHG mitigation ; public policy ; enabler networks ; net-zero roadmap ; developing countries ; social network analysis ; COVID-19 ; COVID-19 response policy ; operational restrictions on facilities ; Night-Time Economy (NTE) ; Night-Time Economic Vitality (NTEV) ; credit-card sales ; PLS-SEM (partial least square structural equation modeling) ; formative measurement model ; superblocks urbanism ; gulf urbanization ; street connectivity and efficiency ; walkability ; sustainable urban development policy and practice ; urban vulnerabilities ; vulnerable communities ; multidisciplinary approach ; disciplinary boundaries ; design workshops ; research by design ; Design for Vulnerables ; Krebs cycle design ; generative urban design ; evidence-based design decision-making ; activity-based model ; transit-oriented development ; amenity accessibility ; green roofs ; sustainable urban planning and design ; urban development ; public perception ; urban policy and governance ; Saudi Arabia ; post-occupancy evaluation ; semantic differential method ; sports parks ; real estate enterprise ; digitalization ; operations management ; barriers ; FTA–DEMATEL–ISM ; sustainability ; heritage redevelopment ; participatory design ; public engagement ; community value ; social value ; Faro Convention ; HUL ; heritage ; cognitive mapping ; urban regeneration ; text mining ; keyword network analysis ; students’ participation ; social network service ; stakeholder ; Korea ; industrial building renovation ; brownfield buildings ; conflicts ; stakeholders ; n/a ; innovation district ; user preferences ; user-centric planning ; decision makers’ perspectives ; urban policy ; Kelvin Grove Urban Village ; Diamantina Knowledge Precinct ; Brisbane Technology Park ; Brisbane ; Australia ; sustainable development ; Central Taiwan Science Park ; green infrastructure ; residents’ opinions ; urban ecosystem ; environmental education ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 93
    Publication Date: 2024-04-01
    Description: On 11 March 2020, the World Health Organisation declared novel coronavirus (SARS-CoV-2) an unprecedented global pandemic. Nearly every country across the globe is struggling to reduce the spread of the COVID-19 virus and to limit its health, societal and economic consequences. As a response to that, with almost immediate effect, students, teachers and workers in general and across the globe were thrown into a new scenario of online work and education. In the midst of this emotional climate laden with fear, uncertainty, sadness and anxiety, millions of students all over the world were confined to their homes and the entire educational community had to adapt to a distance education model. The same occured with workers of different disciplines; they have to balance work and life in the same place. Therefore, homes suddenly became schools, universities and workplaces all at the same time. Against this backdrop, this Special Issue focuses on the study, evaluation and analysis of the opportunities the pandemic offers in three related aspects: first, for building an education for sustainable development. Second, for creating decent working conditions. Finally, to enhance health and well-being both at the workplace and at home. Authors from a range of disciplines, such as education, psychology, management, social sciences and other areas related to sustainable development, have contributed with differrent manuscripts. They address the challenges of studying, working and living in times of uncertainty in order to build sustainable development in those areas from theoretical and applied research.
    Keywords: distance learning systems (DLS) ; higher education institutions (HEI) ; work from home (WFH) ; human resource management (HRM) ; COVID-19 ; principal component analysis (PCA) ; emergency remote teaching and learning (ERTL) ; educational consequences ; parents’ perspectives ; Portugal ; preschool education ; basic education ; secondary education ; digital learning ; sustainable education ; systematic literature review ; university education ; representations ; COVID-19 pandemic ; undergraduate students ; online education ; thematic analysis ; education for sustainable development ; mindfulness ; resilience ; academic performance ; education ; medical ; online learning ; motivation ; classroom education ; pandemic management ; schools closed ; health education ; apprenticeship ; digitization ; distance learning ; school development ; academic dropout ; higher education ; SARS-CoV-2 ; pandemic ; digital competency ; technological resources ; primary education ; post-doctoral researcher ; China ; post-doctoral system ; world-class universities ; internationalization ; teaching ; higher education academy (HEA) ; learning ; STEM ; sustainability ; systematic review ; annotated bibliography ; cultural difference ; group ; post-traumatic stress disorder ; psychological distress ; sleep problems ; internet gaming disorder ; medical education ; medical training ; work life ; Peruvian physicians ; depression ; anxiety ; stress ; burnout ; health-related quality of life ; healthcare professionals ; thema EDItEUR::N History and Archaeology::NH History
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  • 94
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Air pollution is a worldwide environmental hazard that poses serious consequences not only for human health and the climate but also for agriculture, ecosystems, and cultural heritage, among other factors. According to the WHO, there are 8 million premature deaths every year as a result of exposure to ambient air pollution. In addition, more than 90% of the world’s population live in areas where the air quality is poor, exceeding the recommended limits. On the other hand, air pollution and the climate co-influence one another through complex physicochemical interactions in the atmosphere that alter the Earth’s energy balance and have implications for climate change and the air quality. It is important to measure specific atmospheric parameters and pollutant compound concentrations, monitor their variations, and analyze different scenarios with the aim of assessing the air pollution levels and developing early warning and forecast systems as a means of improving the air quality and safeguarding public health. Such measures can also form part of efforts to achieve a reduction in the number of air pollution casualties and mitigate climate change phenomena. This book contains contributions focusing on remote sensing techniques for evaluating air quality, including the use of in situ data, modeling approaches, and the synthesis of different instrumentations and techniques. The papers published in this book highlight the importance and relevance of air quality studies and the potential of remote sensing, particularly that conducted from Earth observation platforms, to shed light on this topic.
    Keywords: tropospheric NO2 concentrations ; nitrogen dioxide ; OMI ; spatio-temporal trends ; DBEST ; PolyTrend ; time-series analysis ; breakpoint detection ; air pollution ; TROPOMI ; COVID ; nitrogen oxides ; satellite-based ; NO2 ; land use regression ; exposure assessment ; carbon monoxide ; COVID-19 ; China ; surface concentration ; IASI ; drone ; UAV ; gas sensors ; odour ; industrial emissions ; mapping ; environmental monitoring ; aerosol optical depth ; CAMS ; machine learning ; MODIS ; urban form ; PM2.5 ; landscape metrics ; geographically weighted regression ; Yunnan Plateau ; biomass burning ; cross-border transport ; WRF-Chem ; formaldehyde ; trend ; satellite ; monitor ; annual ; seasonal ; temperature ; meteorology ; AOD ; Europe ; open data ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RB Earth sciences::RBP Meteorology & climatology
    Language: English
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  • 95
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Cardiothoracic and pulmonary diseases are a significant cause of mortality and morbidity worldwide. The COVID-19 pandemic has highlighted the lack of access to clinical care, the overburdened medical system, and the potential of artificial intelligence (AI) in improving medicine. There are a variety of diseases affecting the cardiopulmonary system including lung cancers, heart disease, tuberculosis (TB), etc., in addition to COVID-19-related diseases. Screening, diagnosis, and management of cardiopulmonary diseases has become difficult owing to the limited availability of diagnostic tools and experts, particularly in resource-limited regions. Early screening, accurate diagnosis and staging of these diseases could play a crucial role in treatment and care, and potentially aid in reducing mortality. Radiographic imaging methods such as computed tomography (CT), chest X-rays (CXRs), and echo ultrasound (US) are widely used in screening and diagnosis. Research on using image-based AI and machine learning (ML) methods can help in rapid assessment, serve as surrogates for expert assessment, and reduce variability in human performance. In this Special Issue, “Artificial Intelligence in Image-Based Screening, Diagnostics, and Clinical Care of Cardiopulmonary Diseases”, we have highlighted exemplary primary research studies and literature reviews focusing on novel AI/ML methods and their application in image-based screening, diagnosis, and clinical management of cardiopulmonary diseases. We hope that these articles will help establish the advancements in AI.
    Keywords: lung ; conventional radiography ; diagnostic procedure ; chronic obstructive pulmonary disease ; COVID-19 ; computed tomography ; lungs ; variability ; segmentation ; hybrid deep learning ; artificial intelligence ; deep learning ; computer-based devices ; radiology ; thoracic diagnostic imaging ; chest X-ray ; CT ; observer tests ; performance ; lung CT images ; nodule detection ; VGG-SegNet ; pre-trained VGG19 ; cardiac amyloidosis ; AL/TTR amyloidosis ; hypertrophic cardiomyopathy ; left ventricular hypertrophy ; convolutional neural network ; Tuberculosis (TB) ; drug resistance ; chest X-rays ; generalization ; localization ; Electrical Impedance Tomography ; lung imaging ; cardiopulmonary monitoring ; aorta ; lung cancer ; pulmonary artery ; pulmonary hypertension ; modality-specific knowledge ; object detection ; RetinaNet ; ensemble learning ; pneumonia ; mean average precision ; source data set ; supervised classification ; coronary artery disease ; machine learning ; cardiopulmonary disease ; faster CNN ; medical imaging ; X-rays ; transfer learning ; explainability ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
    Language: English
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  • 96
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Cardiothoracic and pulmonary diseases are a significant cause of mortality and morbidity worldwide. The COVID-19 pandemic has highlighted the lack of access to clinical care, the overburdened medical system, and the potential of artificial intelligence (AI) in improving medicine. There are a variety of diseases affecting the cardiopulmonary system including lung cancers, heart disease, tuberculosis (TB), etc., in addition to COVID-19-related diseases. Screening, diagnosis, and management of cardiopulmonary diseases has become difficult owing to the limited availability of diagnostic tools and experts, particularly in resource-limited regions. Early screening, accurate diagnosis and staging of these diseases could play a crucial role in treatment and care, and potentially aid in reducing mortality. Radiographic imaging methods such as computed tomography (CT), chest X-rays (CXRs), and echo ultrasound (US) are widely used in screening and diagnosis. Research on using image-based AI and machine learning (ML) methods can help in rapid assessment, serve as surrogates for expert assessment, and reduce variability in human performance. In this Special Issue, “Artificial Intelligence in Image-Based Screening, Diagnostics, and Clinical Care of Cardiopulmonary Diseases”, we have highlighted exemplary primary research studies and literature reviews focusing on novel AI/ML methods and their application in image-based screening, diagnosis, and clinical management of cardiopulmonary diseases. We hope that these articles will help establish the advancements in AI.
    Keywords: lung ; conventional radiography ; diagnostic procedure ; chronic obstructive pulmonary disease ; COVID-19 ; computed tomography ; lungs ; variability ; segmentation ; hybrid deep learning ; artificial intelligence ; deep learning ; computer-based devices ; radiology ; thoracic diagnostic imaging ; chest X-ray ; CT ; observer tests ; performance ; lung CT images ; nodule detection ; VGG-SegNet ; pre-trained VGG19 ; cardiac amyloidosis ; AL/TTR amyloidosis ; hypertrophic cardiomyopathy ; left ventricular hypertrophy ; convolutional neural network ; Tuberculosis (TB) ; drug resistance ; chest X-rays ; generalization ; localization ; Electrical Impedance Tomography ; lung imaging ; cardiopulmonary monitoring ; aorta ; lung cancer ; pulmonary artery ; pulmonary hypertension ; modality-specific knowledge ; object detection ; RetinaNet ; ensemble learning ; pneumonia ; mean average precision ; source data set ; supervised classification ; coronary artery disease ; machine learning ; cardiopulmonary disease ; faster CNN ; medical imaging ; X-rays ; transfer learning ; explainability ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
    Language: English
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  • 97
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This Special Issue of the journal Microorganisms highlights recent publications on the importance of the antimicrobial effect of probiotics. Current research is focused on finding novel or next-generation probiotic strains with antimicrobial properties that can efficiently modulate the ecological taxa composition and functionality of the human microbiota in the gut and beyond. Overall, this Special Issue has brought together new studies on the antimicrobial effects of various novel probiotics from the Weissella, Bacillus, Leuconostoc and Levilactobacillus genera, as well as well-known probiotic food supplements. It also highlights successful applications of probiotics for different infectious diseases including rotaviral gastrointestinal infections, wound infections and even COVID-19.
    Keywords: probiotic ; bacillus subtilis ; antimicrobial ; contact inhibition ; extreme environment ; SARS-CoV-2 ; COVID-19 ; gut microbiome ; probiotics ; Lactobacillus ; Bifidobacteria ; Bacillus ; antimicrobial effect ; in vitro methods ; in silico methods ; carrots ; Caenorhabditis elegans ; pathogen resistance ; Bacillus subtilis ; antimicrobials ; foodborne pathogens ; microbiota ; rotaviruses ; anti-inflammatory ; anticancer ; GRAS ; starter culture ; food ; gut ; beneficial microbes ; wound pathogens ; skin pathogens ; agar spot ; co-culturing ; agar well diffusion ; molecular methods ; PCR ; bacteriocins ; lactic acid bacteria ; Gram-negative bacteria ; Gram-positive bacteria ; nanoencapsulation ; antimicrobial activity ; THP-1 ; dendritic cells ; Levilactobacillus brevis ; SlpB ; CAP-1 ; IL-12 ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 98
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Diet and physical activity are two key modifiable lifestyle factors that influence health across the lifespan (prevention and management of chronic diseases and reduction of the risk of premature death through several biological mechanisms). Community-based interventions contribute to public health, as they have the potential to reach high population-level impact, through the focus on groups that share a common culture or identity in their natural living environment. While the health benefits of a balanced diet and regular physical activity are commonly studied separately, interventions that combine these two lifestyle factors have the potential to induce greater benefits in community groups rather than strategies focusing only on one or the other. Thus, this Special Issue entitled “Combined Nutrition and Exercise Interventions in Community Groups” is comprised of manuscripts that highlight this combined approach (balanced diet and regular physical activity) in community settings. The contributors to this Special Issue are well-recognized professionals in complementary fields such as education, public health, nutrition, and exercise. This Special Issue highlights the latest research regarding combined nutrition and exercise interventions among different community groups and includes research articles developed through five continents (Africa, Asia, America, Europe and Oceania), as well as reviews and systematic reviews.
    Keywords: bone mineral density ; milk intake ; physical activity ; adolescence ; food insecurity ; hunger and health ; nutrition ; health intervention ; formative research ; abdominal obesity ; cardiorespiratory fitness ; hypertriglyceridemic waist phenotype ; lifestyle intervention ; diet quality index ; community-based ; participatory research ; anthropometrics ; fruit and vegetable intake ; Cooperative Extension ; geriatric rehabilitation ; aging ; nutrition education ; aquatic resistance training ; COVID-19 ; dietary habits ; exercise pattern ; adolescents ; cohort study ; feasibility ; colorectal cancer screening ; hospital setting ; France ; health program ; lifestyle ; weight management ; prevention ; service evaluation ; health service ; physical fitness ; diet quality ; factor analysis ; structural equation modeling ; measurement equivalence/invariance ; metabolic syndrome ; cardiometabolic health ; healthy eating ; weight loss ; moderate-to-vigorous physical activity ; sleep ; lifestyle medicine ; preschool children ; motor skills ; Guam ; behaviour change techniques ; weight gain prevention ; reproductive age ; meta-analysis ; meta-regression ; systematic review ; web-based intervention ; health behaviour ; behaviour change ; primary prevention ; nutritionists ; counseling ; randomized controlled trial ; aerobic capacity ; mhealth ; diet ; tailored intervention ; behavior change theory ; Information-Motivation-Behavioral Skills Model ; women ; young adults ; college students ; brief intervention ; metabolic diseases ; gut microbiota ; physical exercise ; community-based intervention ; Latino fathers ; father’s parenting practices ; lifestyle behaviors ; diabetes intervention ; health belief model ; culturally sensitive ; diabetes prevention ; health promotion ; health behaviors ; low and middle income and countries ; community intervention ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
    Language: English
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  • 99
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-11-30
    Description: The Special Issue, titled “Therapeutic Landscapes in Colorectal Carcinoma”, illustrates a stimulating collection of articles written by international specialists that can promote discussions and ideas among colleagues working on CRC. It provides us with a deeper insight into the latest advances involving knowledge on CRC from scientific, translational, and clinical points of view. Through this Special Issue, our main purpose was to shed light on some state-of-the-art research on CRC. Here, the reader will find papers on prognostic factors as well as responses to neoadjuvant and adjuvant CRC treatments. Finally, we discuss the research trends and hotspots for CRC therapies that emerged during the COVID-19 pandemic, such as the potential achievement of a transition from CRC clinical research to precision medicine, together with a special emphasis given to new single-cell-based techniques. We hope that it can encourage translational and interdisciplinary collaborations, leading to a definitive understanding of strategies to overcome and inhibit CRC progression and metastasis.
    Keywords: colorectal cancer ; inflammatory pathways ; NFKB ; RIPK2 ; MSI ; dMMR ; colorectal ; cancer ; immunotherapy ; Romania ; incidence ; PCR ; IHC ; drug development ; targeted therapies ; preclinical candidates ; databases ; cancer therapeutics ; TGF-b ; regorafenib ; colorectal carcinoma ; intratumor heterogeneity ; single-cell next-generation sequencing ; precision medicine ; metastatic colorectal cancer ; BRAF mutation ; triple target therapy ; colorectal cancer screening ; COVID-19 ; SARS-CoV-2 ; colon cancer ; cell line models ; dependencies ; targeted therapy ; signal transduction ; neoadjuvant chemotherapy (NAC) ; locally advanced colon cancer (LACC) ; preoperative treatment ; propensity score matching ; survival ; liver transplantation ; de novo malignancy ; immunosuppression ; uracil–tegafur ; chemotherapy ; adjuvant therapy ; stage IIA ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 100
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The Covid-19 pandemic is having an undeniable impact on all the statements of society. Regarding teaching and learning activities, most educational institutions suspended in-person instruction and moved to remote learning during the lockdown of March and April 2020. Although nowadays many countries have progressively re-opened their educational systems, blended learning is a common practice aimed to reduce the spread of the Covid-19 disease. This disruption has supposed an unprecedented acceleration to the digitalization of teaching and learning. Teaching professionals have been forced to develop their digital competence in a short amount of time, getting mastery in the management of information, the creation of audiovisual contents, and the use of technology to keep their students connected. This Special Issue presents contributions regarding the adoption of distance learning strategies, experiences, or lessons learned in this domain.
    Keywords: collaborative learning ; cooperative competence ; virtual learning ; educational technology ; game-based learning ; relational coordination ; mobile games ; scaffolding strategy ; students’ utilization ; sustainability ; TAM and TUT ; COVID-19 ; convolution neural network ; COVID-19 epidemic ; class loyalty ; decision-making ; digital storytelling ; online participation ; group ; sociality ; digital competence ; soft skills ; university teachers ; TAM ; collaboration ; breakout groups ; translation ; L2 learners ; KSA ; teaching learning center (TLC) ; competence ; pandemic ; computer-mediated communication ; teacher–student relation ; E-learning ; social presence theory ; mobile learning ; distance learning ; Saudi Arabia ; e-learning ; administrators ; proper implementations ; well-structured questionnaires ; un-professionalism ; graded reading ; reading websites/applications ; technology ; EFL ; spring 2020 ; school closures ; Austria ; secondary school teachers ; will–skill–tool model ; digital media implementation ; post-pandemic ; learning media ; behavior intention ; mathematics education ; predictive validity ; general education ; learning algorithms ; online learning ; face-to-face learning ; cross-curricular integration ; music art ; visual art ; remote teaching ; ICT ; interdisciplinary assignments ; elementary education ; learning process ; music subjects ; visual art subjects ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
    Language: English
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