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  • American Institute of Physics (AIP)
  • Blackwell Publishing Ltd
  • Frontiers Media S.A.
  • Nature Publishing Group
  • Wiley-Blackwell
  • 2020-2024  (72)
  • 2020-2023  (78)
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  • 1
    Publication Date: 2024-04-07
    Description: PI3K biology; lymphoma; cancer
    Keywords: PI3K biology; lymphoma; cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 2
    Publication Date: 2024-04-03
    Description: oncogenic drivers; signaling; pathways; hematologic malignancies; cancer
    Keywords: oncogenic drivers; signaling; pathways; hematologic malignancies; cancer ; thema EDItEUR::M Medicine and Nursing
    Language: English
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  • 3
    Publication Date: 2024-03-21
    Description: Precipitation extremes with devastating socioeconomic consequences within the South American Monsoon System (SAMS) are expected to become more frequent in the near future. The complexity in SAMS behavior, however, poses severe challenges for reliable future projections. Thus, robust paleomonsoon records are needed to constrain the high spatiotemporal variability in the response of SAMS rainfall to different climatic drivers. This study uses Ti/Ca ratios from X‐ray fluorescence scanning of a sediment core retrieved off eastern Brazilian to trace precipitation changes over the past 322 Kyr. The results indicate that despite the spatiotemporal complexity of the SAMS, insolation forcing is the primary pacemaker of variations in the monsoonal system. Additional modulation by atmospheric p CO 2 suggests that SAMS intensity over eastern Brazil will be suppressed by rising CO 2 emissions in the future. Lastly, our record reveals an unprecedented strong and persistent wet period during Marine Isotope Stage 6 driven by anomalously strong trade winds.
    Type: Article , PeerReviewed
    Format: text
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  • 4
    Publication Date: 2024-03-21
    Description: Cold‐water coral (CWC) reefs and mounds are and have been biodiversity hotspots of the deep sea. As their occurrence depends on specific environmental parameters, gaining hindsight on changing ocean conditions under on‐going climate change is the key to a better understanding of CWC mound development through time. A convenient technique for reconstructing the palaeoenvironment during periods of CWC mound growth is by extracting geochemical proxies from biologically mediated carbonates. Here, the focus is on probably the two most abundant calcareous archives, that are, cold‐water Scleractinia and Foraminifera, with an overview of the geochemical proxies (selection) used in these aragonitic and calcitic skeletons from CWC mounds. A particular emphasis is set on constraining proxies for temperature, salinity, seawater density, seawater carbonate systems parameters (pH, CO 3 2− ), nutrients, oxygen and water mass tracers.
    Type: Article , PeerReviewed
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  • 5
    Publication Date: 2022-04-01
    Description: We present a workflow to estimate geostatistical aquifer parameters from pumping test data using the Python package welltestpy. The procedure of pumping test analysis is exemplified for two data sets from the Horkheimer Insel site and from the Lauswiesen site, Germany. The analysis is based on a semi‐analytical drawdown solution from the upscaling approach Radial Coarse Graining, which enables to infer log‐transmissivity variance and horizontal correlation length, beside mean transmissivity, and storativity, from pumping test data. We estimate these parameters of aquifer heterogeneity from type‐curve analysis and determine their sensitivity. This procedure, implemented in welltestpy, is a template for analyzing any pumping test. It goes beyond the possibilities of standard methods, for example, based on Theis' equation, which are limited to mean transmissivity and storativity. A sensitivity study showed the impact of observation well positions on the parameter estimation quality. The insights of this study help to optimize future test setups for geostatistical aquifer analysis and provides guidance for investigating pumping tests with regard to aquifer statistics using the open‐source software package welltestpy.
    Description: Article impact statement: We present a workflow to infer parameters of subsurface heterogeneity from pumping test data exemplified at two sites using welltestpy.
    Description: German Federal Environmental Foundation (DBU) http://dx.doi.org/10.13039/100007636
    Keywords: ddc:551.49
    Language: English
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  • 6
    Publication Date: 2022-04-01
    Description: In designed experiments, different sources of variability and an adequate scale of measurement need to be considered, but not all approaches in common usage are equally valid. In order to elucidate the importance of sources of variability and choice of scale, we conducted an experiment where the effects of biochar and slurry applications on soil properties related to soil fertility were studied for different designs: (a) for a field‐scale sampling design with either a model soil (without natural variability) as an internal control or with composited soils, (b) for a design with a focus on amendment variabilities, and (c) for three individual field‐scale designs with true field replication and a combined analysis representative of the population of loess‐derived soils. Three silty loam sites in Germany were sampled and the soil macroaggregates were crushed. For each design, six treatments (0, 0.15 and 0.30 g slurry‐N kg−1 with and without 30 g biochar kg−1) were applied before incubating the units under constant soil moisture conditions for 78 days. CO2 fluxes were monitored and soils were analysed for macroaggregate yields and associated organic carbon (C). Mixed‐effects models were used to describe the effects. For all soil properties, results for the loess sites differed with respect to significant contributions of fixed effects for at least one site, suggesting the need for a general inclusion of different sites. Analysis using a multilevel model allowed generalizations for loess soils to be made and showed that site:slurry:biochar and site:slurry interactions were not negligible for macroaggregate yields. The use of a model soil as an internal control enabled observation of variabilities other than those related to soils or amendments. Experiments incorporating natural variability in soils or amendments resulted in partially different outcomes, indicating the need to include all important sources of variability. Highlights Effects of biochar and slurry applications were studied for different designs and mixed‐effects models were used to describe the effects. Including an internal control allowed observation of, e.g., methodological and analytical variabilities. The results suggested the need for a general inclusion of different sites. Analysis using a multilevel model allowed generalizations for loess soils. The results indicated the need to include all important sources of variability.
    Keywords: ddc:631.4
    Language: English
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  • 7
    Publication Date: 2022-04-01
    Description: Temperate forest soils are often considered as an important sink for atmospheric carbon (C), thereby buffering anthropogenic CO2 emissions. However, the effect of tree species composition on the magnitude of this sink is unclear. We resampled a tree species common garden experiment (six sites) a decade after initial sampling to evaluate whether forest floor (FF) and topsoil organic carbon (Corg) and total nitrogen (Nt) stocks changed in dependence of tree species (Norway spruce—Picea abies L., European beech—Fagus sylvatica L., pedunculate oak—Quercus robur L., sycamore maple—Acer pseudoplatanus L., European ash—Fraxinus excelsior L. and small‐leaved lime—Tilia cordata L.). Two groups of species were identified in terms of Corg and Nt distribution: (1) Spruce with high Corg and Nt stocks in the FF developed as a mor humus layer which tended to have smaller Corg and Nt stocks and a wider Corg:Nt ratio in the mineral topsoil, and (2) the broadleaved species, of which ash and maple distinguished most clearly from spruce by very low Corg and Nt stocks in the FF developed as mull humus layer, had greater Corg and Nt stocks, and narrow Corg:Nt ratios in the mineral topsoil. Over 11 years, FF Corg and Nt stocks increased most under spruce, while small decreases in bulk mineral soil (esp. in 0–15 cm and 0–30 cm depth) Corg and Nt stocks dominated irrespective of species. Observed decadal changes were associated with site‐related and tree species‐mediated soil properties in a way that hinted towards short‐term accumulation and mineralisation dynamics of easily available organic substances. We found no indication for Corg stabilisation. However, results indicated increasing Nt stabilisation with increasing biomass of burrowing earthworms, which were highest under ash, lime and maple and lowest under spruce. Highlights We studied if tree species differences in topsoil Corg and Nt stocks substantiate after a decade. The study is unique in its repeated soil sampling in a multisite common garden experiment. Forest floors increased under spruce, but topsoil stocks decreased irrespective of species. Changes were of short‐term nature. Nitrogen was most stable under arbuscular mycorrhizal species.
    Description: Deutsche Forschungsgemeinschaff (DFG)
    Keywords: ddc:551.9 ; ddc:631.41
    Language: English
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  • 8
    Publication Date: 2022-03-29
    Description: Earthquake Early Warning Systems (EEWSs) represent a technical-scientific challenge aimed at improving the chance of the population exposed to the earthquake shaking of surviving or being less affected. The ability of an EEWS to affect the risk and, in particular, vulnerability and exposure, may determine serious legal responsibilities for people involved in the system, as scientists and experts. The main question concerns, in fact, the relationship between EEWSs and the predictability and avoidability of earthquake effects-i.e., the ground shaking affecting citizens and infrastructures - and the possibility for people to adopt self-protective behavior and/or for industrial infrastructures to be secured. In Italy, natural disasters, such as the 2009 L’Aquila earthquake, teach us that the relationship between science and law is really difficult. So, before EEW’s become operational in Italy, it is necessary to: 1) examine the legislative and technical solutions adopted by some of the international legal systems in countries where this service is offered to citizens; 2) reconstruct the international and European regulatory framework that promotes the introduction of EW systems as life-saving tools for the protection of the right to life and understand whether and how these regulatory texts can impose an obligation on the Italian legal system to develop EEWS; 3) understand what responsibilities could be ascribed to the scientists and technicians responsible for managing EEWS in Italy, analyzing the different impact of vulnerability and exposure on the predictability and avoidability of the harmful event; 4) reflect on the lessons that our legal system will have to learn from other Countries when implementing EEW systems. In order to find appropriate solutions, it is essential to reflect on the opportunity to provide shared and well-structured protocols and creating detailed disclaimers clearly defining the limits of the service. A central role must be recognized to education, because people should not only expect to receive a correct alarm but must be able to understand the uncertainties involved in rapid estimates, be prepared to face the risk, and react in the right way.
    Description: This work has been carried out within the Project ART-IT (Allerta Rapida Terremoti in Italia), funded by the Italian Ministry of University and Research (Progetto Premiale 2015, DM. 850/2017).
    Description: Published
    Description: 685153
    Description: 1SR TERREMOTI - Sorveglianza Sismica e Allerta Tsunami
    Description: JCR Journal
    Keywords: earthquake, early warning, criminal liability, negligence, risk ; Early warning, criminal law, human rights
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 9
    Publication Date: 2022-03-07
    Description: Decades of geochemical monitoring at active crater lakes worldwide have confirmed that variations in major elements and physico-chemical parameters are useful to detect changes in volcanic activity. However, it is still arduous to identify precursors of single phreatic eruptions. During the unrest phase of 2009–2016, at least 679 phreatic eruptions occurred at the hyperacid and hypersaline crater lake Laguna Caliente of Poás volcano (Costa Rica). In this study, we investigate the temporal variations of Rare Earth Elements (REE) dissolved in Laguna Caliente in order to 1) scrutinize if they can be used as a new geochemical tool to monitor changes of phreatic activity at hyperacid crater lakes and 2) identify the geochemical processes responsible for the variations of REE concentrations in the lake. The total concentration of REE varies from 950 to 2,773 μg kg−1. (La/Pr)N-local rock ratios range from 0.93 to 1.35, and Light REE over Heavy REE (LREE/HREE)N-local rock ratios vary from 0.71 to 0.95. These same parameters vary in relation to significant changes in phreatic activity; in particular, the (La/Pr)N-local rock ratio increases as phreatic activity increases, while that of (LREE/HREE)N-local rock decreases when phreatic activity increases. REE concentrations and their ratios were compared with the variations of major elements and physico-chemical parameters of the lake. Calcium versus (La/Pr)N-local rock and versus (LREE/HREE)N-local rock ratios show different trends compared to the other major elements (Na, K, Mg, Al, Fe, SO4, and Cl). Moreover, a higher loss of Ca (up to 2,835 ppm) in lake water was found with respect to the loss of Al, K, and Na. This loss of Ca is argued to be due to gypsum precipitation, a process corroborated by the mass balance calculation simulating the precipitation of gypsum and the contemporaneous removal of REE from the lake water. The observed relations between REE, changes in phreatic activity, and the parameters commonly used for the monitoring of hyperacid volcanic lakes encourage investigating more on the temporal and cause-effect relationship between REE dynamics and changes in phreatic activity at crater lake-bearing volcanoes.
    Description: Published
    Description: 716970
    Description: 5V. Processi eruttivi e post-eruttivi
    Description: 6A. Geochimica per l'ambiente e geologia medica
    Description: 2IT. Laboratori analitici e sperimentali
    Description: JCR Journal
    Keywords: Rare Earth Elements ; Poas Volcano ; phreatic eruptions ; geochemical monitoring ; hyperacid volcanic lakes ; Geochemistry
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
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  • 10
    Publication Date: 2022-03-07
    Description: Coastal and ocean island volcanoes are renowned for having unstable flanks. This can lead to flank deformation on a variety of temporal and spatial scales ranging from slow creep to catastrophic sector collapse. A large section of these unstable flanks is often below sea level, where information on the volcano-tectonic structure and ground deformation is limited. Consequently, kinematic models that attempt to explain measured ground deformation onshore associated with flank instability are poorly constrained in the offshore area. Here, we attempt to determine the locations and the morpho-tectonic structures of the boundaries of the submerged unstable southeastern flank of Mount Etna (Italy). The integration of new marine data (bathymetry, microbathymetry, offshore seismicity, reflection seismic lines) and published marine data (bathymetry, seafloor geodesy, reflection seismic lines) allows identifying the lineament north of Catania Canyon as the southern lateral boundary with a high level of confidence. The northern and the distal (seaward) boundaries are less clear because no microbathymetric or seafloor geodetic data are available. Hypotheses for their locations are presented. Geophysical imaging suggests that the offshore Timpe Fault System is a shallow second-order structure that likely results from extensional deformation within the moving flank. Evidence for active uplift and compression upslope of the amphitheater-shaped depression from seismic data along with subsidence of the onshore Giarre Wedge block observed in ground deformation data leads us to propose that this block is a rotational slump, which moves on top of the large-scale instability. The new shoreline-crossing structural assessment may now inform and improve kinematic models.
    Description: Published
    Description: 810790
    Description: 2V. Struttura e sistema di alimentazione dei vulcani
    Description: JCR Journal
    Keywords: seafloor ; fault ; flank dynamics ; hydroacoustic ; geodesy ; seismic profiles ; 04.07. Tectonophysics ; 04.08. Volcanology ; 04.06. Seismology ; 04.02. Exploration geophysics ; 05.02. Data dissemination
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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