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  • Wiley-Blackwell  (105,844)
  • Oxford University Press  (88,549)
  • 2020-2020
  • 2000-2004  (36,989)
  • 1995-1999  (78,687)
  • 1980-1984  (59,919)
  • 1945-1949  (5,792)
  • 1925-1929
Collection
Keywords
Publisher
Years
Year
  • 1
    Unknown
    Thinking it through : an introduction to contemporary philosophy (2003)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Philosophy, Introductions.
    Notes: Mind -- Knowledge -- Language -- Science -- Morality -- Politics -- Law -- Metaphysics -- Philosophy
    Pages: xviii, 412 p.
    ISBN: 0-19-518393-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=120898
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    E-Book (German National Licenses)
  • 2
    Unknown
    In defense of globalization (2004)
    New York : Oxford University Press
    Details
    Keywords: Anti-globalization movement. ; Globalization, Economic aspects. ; Globalization, Social aspects.
    Notes: I. Coping with anti-globalization -- 1. Anti-globalization: why? -- 2. Globalization: socially, not just economically, benign -- 3. Globalization is good but not good enough -- 4. Non-government organizations -- II. Globalization's human face: trade and corporations -- 5. Poverty: enhanced or diminished? -- 6. Child labor: increased or reduced? -- 7. Women: harmed or helped? -- 8. Democracy at bay? -- 9. Culture imperiled or enriched? -- 10. Wages and labor standards at stake? -- 11. Environment in peril? -- 12. Corporations: predatory or beneficial? -- III. Other dimensions of globalization -- 13. The perils of Gung-Ho International Financial capitalism -- 14. International flows of humanity -- IV. Appropriate governance: making globalization work better -- 15. Appropriate governance: an overview -- 16. Coping with downsides -- 17. Accelerating the achievement of social agendas -- 18. Managing transitions: optimal, not maximal, speed -- V. In conclusion -- 19. And so, let us begin anew
    Pages: xi, 308 p.
    ISBN: 0-19-530391-1
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129267
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  • 3
    Unknown
    Handbook of affective sciences : Affective sciences (2003)
    Oxford ; New York : Oxford University Press
    Series in affective science  
    Details
    Keywords: Affect (Psychology) ; Electronic books ; Emotions
    Pages: xvii, 1199 p.
    ISBN: 0-19-530205-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129691
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  • 4
    Unknown
    Encounters with God : an approach to the theology of Jonathan Edwards (2000)
    New York : Oxford University Press
    Religion in America series  
    Details
    Keywords: Edwards, Jonathan,, 1703-1758.
    Pages: xii, 194 p.
    ISBN: 0-585-30895-0
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23547
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  • 5
    Unknown
    Understanding truth (2000)
    New York : Oxford University Press
    Details
    Keywords: Truth.
    Pages: ix, 268 p.
    ISBN: 0-585-32455-7
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23592
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  • 6
    Unknown
    American Lazarus : religion and the rise of African-American and native American literatures (2003)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Occom, Samson,, 1723-1792. ; African Americans in literature. ; African Americans, Intellectual life. ; American literature, African American authors, History and criticism. ; American literature, Indian authors, History and criticism. ; American literature, 1783-1850, History and criticism. ; American literature, Colonial period, ca. 1600-1775, History and criticism. ; American literature, Revolution, 1775-1783, History and criticism. ; Christian literature, American, History and criticism. ; Christianity and literature, United States, History, 18th century. ; Hymns, English, United States, History and criticism. ; Indians in literature. ; Indians of North America, Intellectual life.
    Pages: vi, 255 p.
    ISBN: 0-19-518567-6
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=92702
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  • 7
    Unknown
    Welfare as we knew it : a political history of the American welfare state (2000)
    New York : Oxford University Press
    Details
    Keywords: United States, Social policy. ; Public welfare, United States, History.
    Pages: 210 p.
    ISBN: 0-585-35667-X
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=53587
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  • 8
    Unknown
    Memory and emotion (2004)
    Oxford ; New York : Oxford University Press
    Series in affective science  
    Details
    Keywords: Autobiographical memory. ; Brain, physiology. ; Emotions. ; Emotions, physiology. ; Memory, physiology. ; Mental Disorders, psychology. ; Psychiatry. ; Psychophysiology.
    Notes: Memory for emotional events / Daniel Reisberg and Friderike Heuer -- The neuroanatomy of emotional memory in humans / Tony W. Buchanan and Ralph Adolphs -- The biopsychology of trauma and memory / Jessica D. Payne ... [et al.] -- Forgetting trauma? / Richard J. McNally, Susan A. Clancy, and Heidi M. Barrett -- Selective memory effects in anxiety disorders : an overview of research findings and their implications / Colin MacLeod and Andrew Mathews -- Memory for emotional and nonemotional events in depression : a question of habit? / Paula Hertel -- Emotion, memory, and conscious awareness in schizophrenia / Jean-Marie Danion ... [et al.] -- Children's memories of emotional events / Robyn Fivush and Jessica McDermott Sales -- Aging and emotional memory / Mara Mather -- Emotion and eyewitness memory / Robin S. Edelstein ... [et al.] -- Emotional memory in survivors of the Holocaust : a qualitative study of oral testimony / Robert N. Kraft
    Pages: xiv, 413 p.
    ISBN: 0-19-518650-8
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=121006
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  • 9
    Unknown
    The Oxford dictionary of saints (2000)
    New York : Oxford University Press
    Oxford paperback reference  
    Details
    Keywords: Christian saints, Biography, Dictionaries. ; Christian saints, Great Britain, Biography, Dictionaries. ; Christian saints, Ireland, Biography, Dictionaries. ; Saints chrétiens, Biographies, Dictionnaires anglais. ; Saints chrétiens, Grande-Bretagne, Biographies, Dictionnaires anglais. ; Saints chrétiens, Irlande, Biographies, Dictionnaires anglais.
    Pages: xxv, 547 p.
    Edition: 4th ed
    ISBN: 0-585-11034-4
    URL: http://www.netlibrary.com/urlapi.asp?action=summary&v=1&bookid=12301
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  • 10
    Unknown
    Evangelicals and science in historical perspective (2000)
    New York : Oxford University Press
    Religion in America series  
    Details
    Keywords: Evangelicalism, History. ; Religion and science, History.
    Notes: The history of science and religion : some evangelical dimensions / John Hedley Brooke -- The Puritan thesis revisited / John Morgan -- Christianity and early modern science : the Foster thesis reconsidered / Edward B. Davis -- Science, theology, and society : from Cotton Mather to William Jennings Bryan / Mark A. Noll -- Science and evangelical theology in Britain from Wesley to Orr / David W. Bebbington -- Science, natural theology, and evangelicalism in early nineteenth-century Scotland : Thomas Chalmers and the Evidence controversy / Jonathan R. Topham -- Scriptural geology in America / Rodney L. Stiling -- Situating evangelical responses to evolution / David N. Livingstone -- Telling tales : evangelicals and the Darwin legend / James Moore -- Creating creationism : meanings and uses since the age of Agassiz / Ronald L. Numbers -- A sign for an unbelieving age : evangelicals and the search for Noah's ark / Larry Eskridge -- "The science of duty" : moral philosophy and the epistemology of science in nineteenth-century America / Allen C. Guelzo -- Toward a Christian social science in Canada, 1890-1930 / Michael Gauvreau and Nancy Christie -- Evangelicals, Biblical scholarship, and the politics of the modern American academy / D.G. Hart -- The meaning of science for Christians : a new dialogue on Olympus / George Marsden
    Pages: vi, 351 p.
    ISBN: 0-585-18275-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23620
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  • 11
    Unknown
    When information came of age : technologies of knowledge in the age of reason and revolution, 1700-1850 (2000)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Europe, Intellectual life, 18th century. ; Europe, Intellectual life, 19th century. ; Europe, Vie intellectuelle, 18e siècle. ; Europe, Vie intellectuelle, 19e siècle. ; Enlightenment. ; Information resources, Europe, History, 18th century. ; Information resources, Europe, History, 19th century. ; Learning and scholarship, Europe, History, 18th century. ; Learning and scholarship, Europe, History, 19th century. ; Savoir et érudition, Europe, Histoire, 18e siècle. ; Savoir et érudition, Europe, Histoire, 19e siècle. ; Siècle des lumières. ; Sources d'information, Europe, Histoire, 18e siècle. ; Sources d'information, Europe, Histoire, 19e siècle.
    Pages: viii, 246 p.
    ISBN: 0-19-518040-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=92690
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  • 12
    Unknown
    Studies in classical history and society (2002)
    Oxford [England] ; New York : Oxford University Press
    American classical studies  
    Details
    Keywords: Greece, History, To 146 B.C. ; Grèce, Histoire, Jusqu'à 146 av. J.-C. ; Rome, Histoire. ; Rome, History. ; Civilisation ancienne. ; Civilization, Classical.
    Pages: xi, 151 p.
    ISBN: 0-19-518490-4
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=121005
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  • 13
    Unknown
    Gendarmes and the state in nineteenth-century Europe (2000)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Police, Europe, Histoire. ; Police, Europe, History. ; Police, Europe, History, 19th century. ; Police, France, Histoire. ; Police, France, History.
    Pages: x, 288 p.
    ISBN: 0-585-48633-6
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=100298
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  • 14
    Unknown
    Englishness identified : manners and character, 1650-1850 (2000)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Angleterre, Mœurs et coutumes, 17e siècle. ; Angleterre, Mœurs et coutumes, 18e siècle. ; Angleterre, Mœurs et coutumes, 19e siècle. ; England, Social life and customs, 17th century. ; England, Social life and customs, 17th century. ; England, Social life and customs, 18th century. ; England, Social life and customs, 19th century. ; Anglais dans la littérature. ; Anglais, Histoire. ; English literature, History and criticism. ; Littérature anglaise, Histoire et critique. ; National characteristics, English, in literature. ; National characteristics, English, History.
    Notes: Energy -- Candour -- Decency -- Taciturnity -- Reserve -- Eccentricity -- Manners and character
    Pages: x, 389 p.
    ISBN: 0-585-48625-5
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=100309
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  • 15
    Unknown
    Armies without nations : public violence and state formation in Central America, 1821-1960 (2004)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Central America, Politics and government. ; Political violence, Central America, History. ; State-sponsored terrorism, Central America, History.
    Notes: Part 1 : 1821-1939. Historical dimensions of public violence in Latin America -- Binding hatreds : public violence, state, and nation in Central American history -- Guatemala : organizing for war -- El Salvador : a democracy of violence -- Honduras : caudillos in search of an army -- Nicaragua : a new army finds its caudillo -- Costa Rica : caudillos in search of a state -- Part 2 : 1940-1960. Transformations -- Defining collaboration : the United States and Central America -- Guatemala : "Showcase of Latin America" -- El Salvador : distrustful collaborator -- Honduras : remaking an "armed rabble" -- Nicaragua : "Ready to receive orders from Uncle Sam" -- Costa Rica : an army renamed -- Conclusions -- Statistical appendix -- Notes
    Pages: x, 336 p.
    ISBN: 0-19-518573-0
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=121469
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  • 16
    Unknown
    The conscious mind : in search of a fundamental theory (2000)
    New York : Oxford University Press
    Philosophy of mind series  
    Details
    Keywords: Consciousness. ; Dualism. ; Mind and body. ; Philosophy of mind.
    Pages: xvii, 414 p.
    ISBN: 0-585-35313-1
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=55770
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  • 17
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    Sight unseen : an exploration of conscious and unconscious vision (2004)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Electronic books ; Vision disorders ; Visual perception
    Pages: ix, 135 p.
    ISBN: 1-423-70567-X
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=130746
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  • 18
    Unknown
    American mobbing, 1828-1861 : toward Civil War (2000)
    New York : Oxford University Press
    Details
    Keywords: United States, History, Civil War, 1861-1865, Causes. ; United States, Race relations. ; United States, Social conditions, To 1865. ; Antislavery movements, United States, History, 19th century. ; Riots, United States, History, 19th century. ; Slavery, Government policy, United States. ; Violence, United States, History, 19th century.
    Pages: xx, 372 p.
    ISBN: 0-19-530397-0
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=120981
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  • 19
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    The changing shape of English nonconformity, 1825-1925 (2000)
    New York, N.Y : Oxford University Press
    Details
    Keywords: Dissenters, Religious, England, History, 19th century. ; Dissenters, Religious, England, History, 20th century. ; Dissidents (Religion), Angleterre, Histoire, 19e siècle. ; Dissidents (Religion), Angleterre, Histoire, 20e siècle. ; Theology, Study and teaching, England, History, 19th century. ; Theology, Study and teaching, England, History, 20th century. ; Théologie, Étude et enseignement, Angleterre, Histoire, 19e siècle. ; Théologie, Étude et enseignement, Angleterre, Histoire, 20e siècle.
    Pages: 248 p.
    ISBN: 0-585-16245-X
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23559
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  • 20
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    Charles Dickens in cyberspace : the afterlife of the nineteenth century in postmodern culture (2003)
    New York : Oxford University Press
    Details
    Keywords: Great Britain, Civilization, 19th century. ; United States, Civilization, British influences. ; United States, Civilization, 20th century. ; Dickens, Charles,, 1812-1870, Appreciation, United States. ; Criticism, United States, History, 20th century. ; English literature, Appreciation, United States. ; English literature, 19th century, History and criticism, Theory, etc. ; Literature and science, Great Britain. ; Literature and science, United States. ; Postmodernism (Literature), United States. ; Romanticism, Great Britain.
    Pages: x, 270 p.
    ISBN: 0-19-518078-X
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=92722
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  • 21
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    The Gospel according to John : a literary and theological commentary (2000)
    New York : Oxford University Press
    Details
    Keywords: Bible., N.T., John. ; Bible., N.T., John, Commentaries.
    Pages: xiii, 625 p.
    Edition: Pbk. rpt. ed., 1997
    ISBN: 0-585-27829-6
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23535
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  • 22
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    Minds and bodies : philosophers and their ideas (2000)
    New York, N.Y : Oxford University Press
    Philosophy of mind series  
    Details
    Keywords: Ethics, Book reviews. ; Mind and body, Book reviews. ; Philosophy of mind, Book reviews.
    Pages: viii, 264 p.
    ISBN: 0-585-16169-0
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23637
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  • 23
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    Warranted Christian belief (2000)
    New York : Oxford University Press
    Details
    Keywords: Apologetics. ; Christianity, Philosophy. ; Faith and reason, Christianity.
    Pages: xx, 508 p.
    ISBN: 0-585-35267-4
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=55794
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  • 24
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    Mobilizing the information society : strategies for growth and opportunity (2000)
    New York, N.Y : Oxford University Press
    Details
    Keywords: Information society. ; Société informatisée.
    Pages: xxiii, 516 p.
    ISBN: 0-585-35755-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=56409
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  • 25
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    Social identity, intergroup conflict, and conflict reduction (2001)
    Oxford [England] ; New York, N.Y. [USA] : Oxford University Press
    Rutgers series on self and social identity  
    Details
    Keywords: Conflict management. ; Ethnic relations. ; Gestion des conflits. ; Group identity. ; Identité collective. ; Relations interethniques.
    Notes: Introduction : social identity and intergroup conflict / Lee Jussim, Richard D. Ashmore, and David Wilder / Ingroup identification and intergroup conflict : when does ingroup love become outgroup hate? / Marilynn B. Brewer -- Ethnic identity, national identity, and intergroup conflict : the significance of personal experiences / Thomas Hylland Eriksen -- The meaning of american national identity : patterns of ethnic conflict and consensus / Jack Citrin, Cara Wong, and Brian Duff -- Communal and national identity in a multiethnic state : a comparison of three perspectives / Jim Sidanius and John R. Petrocik -- Social and role identities and political violence : identity as a window on violence in northern ireland / Robert W. White -- Individual and group identities in genocide and mass killing / Ervin Staub -- The role of national identity in conflict resolution : experiences from Israeli-Palestinian problem-solving workshops / Herbert C. Kelman -- Conclusion : toward a social identity framework for intergroup conflict / Richard D. Ashmore, Lee Jussim, David Wilder, and Jessica Heppen
    Pages: xii, 270 p.
    ISBN: 0-19-530241-9
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129724
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  • 26
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    The handbook of culture & psychology : Handbook of culture and psychology (2001)
    New York : Oxford University Press
    Details
    Keywords: Ethnopsychology. ; Personality and culture.
    Notes: Culture and psychology at a crossroad : historical perspective and theoretical analysis / John Adamopoulos and Walter J. Lonner -- Individualism and collectivism : past, present, and future / Harry C. Tirandis -- Culture, science, and indigenous psychologies : an integrated analysis / Uichol Kim -- The evolution of cross-cultural research methods / Fons van de Vijver -- Culture, context, and development / Harry W. Gardiner -- Cognition across cultures / R.C. Mishra -- Everyday cognition : where culture, psychology, and education come together / Analúcia D. Schliemann and David W. Carraher -- Culture and moral development / Joan G. Miller -- Culture and emotion / David Matsumoto -- Gender and culture / Deborah L. Best and John E. Williams -- Culture and control orientations / Susumu Yamaguchi -- Culture and human inference : perspectives from three traditions / Kaiping Peng, Daniel R. Ames, and Eric D. Knowles -- Abnormal psychology and culture / Junko Tanaka-Matsumi -- Clinical psychology and culture / Jayne Lee and Stanley Sue -- Polishing the jade : a modest proposal for improving the study of social psychology across cultures / Michael Harris Bond and James T. Tedeschi -- Culture and social cognition : toward a social psychology of cultural dynamics / Yoshihisa Kashima -- Cross-cultural studies of social influence / Peter B. Smith -- Social justice from a cultural perspective / Kwok Leung and Walter G. Stephan -- The A, B, Cs of acculturation / Colleen Ward
    Pages: xvi, 458 p.
    ISBN: 0-19-530227-3
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129712
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  • 27
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    Thinking about feeling : contemporary philosophers on emotions (2004)
    Oxford ; New York : Oxford University Press
    Series in affective science  
    Details
    Keywords: Emotions (Philosophy)
    Notes: Emotions, physiology, and intentionality.Primitive emotions /John Deigh --Emotion : biological fact or social construction /Jenefer Robinson --Embodied emotions /Jesse Prinz --Emotion, appraisal, and cognition.Emotions : what I know, what I'd like to think I know, and what I'd like to think /Ronald de Sousa --Emotions, thoughts, and feelings : emotions as engagements with the world /Robert C. Solomon --Emotions and feelings.Emotion, feeling, and knowledge of the world /Peter Goldie --Subjectivity and emotion /Cheshire Calhoun --Emotions and rationality.Emotions, rationality, and mind/body /Patricia Greenspan --Some considerations about intellectual desire and emotions /Michael Stocker --Emotions, action, and freedom.Emotion and action /Jon Elster --Emotions and freedom /Jerome Neu --Emotion and value.Emotions as judgments of value and importance /Martha Nussbaum --Feelings that matter /Annette Baier --Perturbations of desire : emotions disarming morality in the "Great song" of The Mahabharata /Purushottama Bilimoria --On theories of emotion.Is emotion a natural kind? /Paul E. Griffiths --Emotion as a subtle mental mode /Aaron Ben-Zeev --Enough already with "Theories of emotions" /Amelie Oksenberg Rorty.
    Pages: x, 297 p.
    ISBN: 0-19-530334-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129793
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  • 28
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    The foundations of mind : origins of conceptual thought (2004)
    Oxford ; New York : Oxford University Press
    Oxford series in cognitive development  
    Details
    Keywords: Cognition in infants. ; Cognition, physiology, Infant. ; Concepts in infants. ; Thinking, physiology, Infant.
    Notes: How to build a baby : prologue -- Piaget's sensorimotor infant -- Kinds of representation : seeing and thinking -- Perceptual meaning analysis and image-schemas : the infant as interpreter -- Some image-schemas and their functions -- Some differences between percepts and concepts : the case of the basic level -- Some preverbal concepts -- Conceptual categories as induction machines -- Continuity in the conceptual system : acquisition, breakdown, and reorganization -- Recall of the past -- Language acquisition -- Consciousness and conclusions
    Pages: xiii, 359 p.
    ISBN: 0-19-530396-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129820
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  • 29
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    The quest for reality : subjectivism and the metaphysics of colour (2000)
    New York : Oxford University Press
    Details
    Keywords: Color (Philosophy)
    Pages: xv, 228 p.
    ISBN: 0-585-36474-5
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=55844
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  • 30
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    Twentieth century sprawl : highways and the reshaping of the American Landscape ; Highways transformed America (2004)
    New York : Oxford University Press
    Details
    Keywords: Denver (Colo.), History, 20th century. ; Middlebury (Vt. : Town), History, 20th century. ; Smyrna (Rutherford County, Tenn.), History, 20th century. ; Cities and towns, United States, Growth, History, 20th century, Case studies. ; Interstate Highway System, History, 20th century. ; Roads, Government policy, United States, History, 20th century. ; Transportation, Automotive, United States, History, 20th century.
    Notes: Highway federalism -- Denver meets the automobile -- The decentralization of post-World War II Denver -- Automobiles and a small town -- Bridges, bypasses, and boulevards -- AutoCity : Smyrna, Tennessee
    Pages: xiv, 297 p.
    ISBN: 0-19-530264-8
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129257
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  • 31
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    A leap in the dark : the struggle to create the American republic (2003)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: United States, History, 1783-1815. ; United States, History, Colonial period, ca. 1600-1775. ; United States, History, Revolution, 1775-1783.
    Notes: Preface -- 1754-1763 : Join, or die -- 1763-1766 : Loss of respect and affection -- 1766-1770 : To crush the spirit of the colonies -- 1770-1774 : Cause of Boston now is the cause of America -- 1775-1776 : To die freemen rather than to live slaves -- 1776-1777 : Leap into the dark -- 1778-1782 : This wilderness of darkness and dangers -- 1783-1787 : Present paroxysm of our affairs -- 1787-1789 : So much unanimity and good will -- 1790-1793 : Prosperous at home, respectable abroad -- 1793-1796 : Colossus to the Antirepublican party -- 1797-1799 : Game where principles are the stake -- 1799-1801 : Gigg is up -- 1801 : Age of revolution and reformation
    Pages: xv, 558 p.
    ISBN: 0-19-518418-1
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=120918
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    Garden spot : Lancaster County, the old order Amish, and the selling of rural America (2002)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Amish Country (Pa.) ; Lancaster County (Pa.), Rural conditions. ; Rural development, Pennsylvania, Lancaster County.
    Notes: Introduction: a fertile soil -- Cultivating the garden : the invention of Lancaster County -- Pride and progress : education, literacy, and the little red schoolhouse -- Dutch country : the Amish and tourism -- Domain of abundance : food and farming -- Landscape of progress : urbanization and planning -- Preserving the garden : development and farm preservation -- Epilogue: the harvest -- Appendix : Farms and population of Lancaster County, 1900-2000
    Pages: x, 258 p.
    ISBN: 0-19-518029-1
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=92724
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    The human side of M & A : how CEOs leverage the most important asset in deal making ; Human side of M and A ; Human side of mergers and acquisitions ; Leveraging the most important factor in deal making (2004)
    New York : Oxford University Press
    Details
    Keywords: Consolidation and merger of corporations. ; Human capital. ; Organizational effectiveness.
    Pages: xi, 193 p.
    ISBN: 0-19-518406-8
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=120907
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    Thought experiments (2000)
    New York : Oxford University Press
    Details
    Keywords: Philosophy and science. ; Thought experiments.
    Pages: xii, 318 p.
    Edition: [Pbk. reprint 1998]
    ISBN: 0-585-16074-0
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23526
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  • 35
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    Postmodernism : a very short introduction (2002)
    Oxford ; New York : Oxford University Press
    Very short introductions  
    Details
    Keywords: Postmodernism.
    Pages: 142 p.
    ISBN: 0-585-48631-X
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=100292
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    Organizational participation : myth and reality (2000)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Industrial relations. ; Organizational behavior. ; Organizational sociology.
    Pages: x, 294 p.
    ISBN: 0-585-36603-9
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=56038
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  • 37
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    Understanding genocide : the social psychology of the Holocaust (2002)
    New York : Oxford University Press
    Details
    Keywords: Holocaust, Jewish (1939-1945), Influence. ; Holocaust, Jewish (1939-1945), Psychological aspects. ; Holocaust, Jewish (1939-1945), Social aspects. ; Social sciences, Philosophy.
    Notes: The psychology of bystanders, perpetrators, and heroic helpers / Ervin Staub -- What is a "social-psychological" account of perpetrator behavior? The person versus the situation in Goldhagen's Hitler's willing executioners / Leonard S. Newman -- Authoritarianism and the Holocaust: some cognitive and affective implications / Peter Suedfeld and Mark Schaller -- Perpetrator behavior as destructive obedience: an evaluation of Stanley Milgram's perspective, the most influential social-psychological approach to the Holocaust / Thomas Blass -- Sacrificial lambs dressed in wolves' clothing: envious prejudice, ideology, and the scapegoating of Jews / Peter Glick -- Group processes and the Holocaust / R. Scott Tindale ... [et al.] -- Examining the implications of cultural frames on social movements and group action / Daphna Oyserman and Armand Lauffer -- Population and predators: preconditions for the Holocaust from a control-theoretical perspective / Dieter Frey and Helmut Rez -- The zoomorphism of human collective violence / R.B. Zajonc -- The Holocaust and the four roots of evil / Roy F. Baumeister -- Instigators of genocide: examining Hitler from a social-psychological perspective / David R. Mandel -- Perpetrators with a clear conscience: lying self-deception and belief change / Ralph Erber -- Explaining the Holocaust: does social psychology exonerate the perpetrators? / Arthur G. Miller, Amy M. Buddie, and Jeffrey Kretschmar -- Epilogue: Social psychologists confront the Holocaust / Leonard S. Newman and Ralph Erber
    Pages: xi, 360 p.
    ISBN: 0-19-518618-4
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=120998
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    The American dream : a short history of an idea that shaped a nation (2003)
    Oxford [England] ; New York : Oxford University Press
    Details
    Keywords: United States, Civilization, Philosophy. ; United States, Politics and government, Philosophy. ; National characteristics, American. ; Social values, United States.
    Notes: Introduction: A dream country -- Dream of the good life (I) : the Puritan enterprise -- Dream charter : The declaration of independence -- Dream of the good life (II) : upward mobility -- King of America : the dream of equality -- Detached houses : the dream of home ownership -- Dream of the good life (III) : the coast -- Conclusion: Extending the dream
    Pages: x, 214 p.
    ISBN: 0-19-530398-9
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129263
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  • 39
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    Feminism and history : Feminism & history (2000)
    New York : Oxford University Press
    Oxford readings in feminism  
    Details
    Keywords: Feminist theory. ; Women, History.
    Notes: Does a sex have a history? /Denise Riley --The dialects of Black womanhood /Bonnie Thornton Dill --Theorizing woman:Funu, Guojia, Jiating (Chinese women, Chinese state, Chinese family) /Tani Barlow --'Women's history' in transition: the European case /Natalie Zemon Davis --The traffic in women: notes on the 'political economy' of sex /Gayle Rubin --Gender: a useful category of historical analysis /Joan Wallach Scott --African-American women's history and the metalanguge of race /Evelyn Brooks Higginbotham --Carnal knowledge.
    Pages: ix, 611 p.
    ISBN: 0-585-15703-0
    URL: http://www.netlibrary.com/urlapi.asp?action=summary&v=1&bookid=12418
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  • 40
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    New directions in American religious history (2000)
    New York : Oxford University Press
    Details
    Keywords: United States, Church history, Congresses. ; Christianity, United States, Congresses.
    Pages: ix, 502 p.
    ISBN: 0-585-30487-4
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23593
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  • 41
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    At war with ourselves : why America is squandering its chance to build a better world (2004)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: United States, Foreign relations, Philosophy. ; United States, Foreign relations, 2001- ; Globalization, Political aspects. ; National characteristics, American.
    Pages: xiv, 288 p.
    Edition: [Pbk. ed.]
    ISBN: 0-19-518433-5
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=120929
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  • 42
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    Feminism and science : Feminism & science (2000)
    Oxford : Oxford University Press
    Oxford readings in feminism  
    Details
    Keywords: Feminist theory. ; Science, Philosophy. ; Science, Social aspects. ; Women in science.
    Pages: vii, 289 p.
    ISBN: 0-585-12065-X
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=12414
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  • 43
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    When flesh becomes word : an anthology of early eighteenth-century libertine literature (2004)
    New York : Oxford University Press
    Details
    Keywords: English literature, 18th century. ; Erotic literature, English. ; Libertinism, Literary collections.
    Notes: British libertine literature before Fanny Hill (1749) -- 1: The school of Venus (1680) -- 2: The pleasure of a single life (1701), The fifteen comforts of Cuckoldom (1706), and the fifteen plagues of a maiden-head (1707) -- 3: Gonosologium Novum (1709) -- 4: Venus in the cloister (1725) -- 5: A dialogue between a married lady and a maid (1740) -- 6: A new description of merryland (1741) -- 7: The female husband (1746)
    Pages: xxxiii, 332 p.
    ISBN: 0-19-518577-3
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=120996
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  • 44
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    Democracies in flux : the evolution of social capital in contemporary society (2002)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Capital social (Sociologie) ; Civil society. ; Democracy. ; Démocratie. ; Social capital (Sociology) ; Société civile.
    Notes: Introduction /Robert D. Putnam and Kristin A. Goss --Great Britain: the role of government and the distribution of social capital /Peter A. Hall --United States: bridging the privileged and the marginalized? /Robert Wuthnow --United States: from membership to advocacy /Theda Skocpol --France: old and new civic and social ties in France /Jean-Pierre Worms --Decline of social capital?: the German case /Claus Offe and Susanne Fuchs --From civil war to civil society: social capital in Spain from the 1930s to the 1990s /Victor Pérez-Díaz --Sweden: social capital in the social democratic state /Bo Rothstein --Australia: making the lucky country /Eva Cox --Broadening the basis of social capital in Japan /Takashi Inoguchi --Conclusion /Robert D. Putnam.
    Pages: 516 p.
    ISBN: 0-19-518460-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=120945
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    The Oxford companion to philosophy (2000)
    Oxford : Oxford University Press
    Details
    Keywords: Philosophie, Encyclopédies. ; Philosophy, Encyclopedias.
    Pages: xviii, 1009 p.
    ISBN: 0-585-18263-9
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=22941
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  • 46
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    Holy war, holy peace : how religion can bring peace to the Middle East (2002)
    New York, N.Y : Oxford University Press
    Details
    Keywords: Arab-Israeli conflict, Religious aspects. ; Arab-Israeli conflict, 1993-, Peace. ; Religion and politics, Middle East.
    Pages: viii, 269 p.
    ISBN: 0-19-518512-9
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=121463
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  • 47
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    There are no slaves in France : the political culture of race and slavery in the Ancien ReÌgime (2000)
    New York : Oxford University Press
    Details
    Keywords: France, Race relations, History, 18th century. ; Blacks, Legal status, laws, etc., France, History, 18th century. ; Political culture, France, History, 18th century. ; Racism, France, History, 18th century.
    Pages: x, 210 p.
    ISBN: 0-585-32788-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=53439
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  • 48
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    Bowing to necessities : a history of manners in America, 1620-1860 (2000)
    New York : Oxford University Press
    Details
    Keywords: Etiquette, United States, History.
    Notes: Part I -- Hierarchy: manners in a vertical social order, 1620-1740.Manners for gentlemenManners over minorsManners maketh menPart II --Revolution: an opening of possibilities, 1740-1820.Middle class risingYouth risingWomen risingPart III -- Resolution: manners for democrats, 1820-1860.Manners for the middle classManners for adultsLadies first?
    Pages: x, 310 p.
    ISBN: 0-19-530339-3
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129794
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    The Oxford dictionary of the Jewish religion (2000)
    New York : Oxford University Press
    Details
    Keywords: Judaism, Dictionaries.
    Pages: xviii, 764 p.
    ISBN: 0-585-38345-6
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=53320
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  • 50
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    Marriage wars in late Renaissance Venice (2001)
    Oxford ; New York : Oxford University Press
    Studies in the history of sexuality  
    Details
    Keywords: Venice (Italy), Social conditions, To 1797 ; Electronic books ; Marriage, History, Italy, Venice ; Renaissance, Italy, Venice
    Pages: xi, 221 p.
    ISBN: 0-19-518018-6
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=92688
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  • 51
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    Joyce's revenge : history, politics, and aesthetics in Ulysses (2002)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Great Britain, Relations, Ireland. ; Ireland, In literature. ; Ireland, Relations, Great Britain. ; Joyce, James,, 1882-1941., Ulysses. ; Joyce, James,, 1882-1941, Aesthetics. ; Joyce, James,, 1882-1941, Political and social views. ; Literature and history, Ireland, History, 20th century. ; Politics and literature, Ireland, History, 20th century.
    Pages: xii, 306 p.
    ISBN: 0-585-48623-9
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=100300
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  • 52
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    The Oxford dictionary of philosophy : Dictionary of philosophy (2000)
    New York : Oxford University Press
    Oxford paperback reference  
    Details
    Keywords: Philosophie, Dictionnaires anglais. ; Philosophy, Dictionaries.
    Pages: ix, 418 p.
    ISBN: 0-585-11072-7
    URL: http://www.netlibrary.com/urlapi.asp?action=summary&v=1&bookid=12313
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  • 53
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    Susanna Wesley : the complete writings (2000)
    New York : Oxford University Press
    Details
    Keywords: Wesley, Susanna Annesley,, 1669-1742. ; Wesley, Susanna Annesley,, 1670-1742. ; Anglicans, England, Biography.
    Pages: xiv, 504 p.
    ISBN: 0-585-24572-X
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=23631
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  • 54
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    The crime in mind : criminal responsibility and the Victorian novel (2003)
    New York : Oxford University Press
    Details
    Keywords: Crime in literature. ; Criminal liability in literature. ; Criminals in literature. ; English fiction, 19th century, History and criticism. ; Law and literature, History, 19th century. ; Legal stories, English, History and criticism. ; Responsibility in literature.
    Notes: Organizing crime : conduct and character in Oliver Twist : prologue to George Eliot's crimes -- "To fix our minds on that consequence" : minding consequences in Adam Bede and Felix Holt -- Middlemarch, Daniel Deronda, and the crime in mind -- James Fitzjames Stephen and the responsibilities of narrative -- Modern responsibilities
    Pages: viii, 275 p.
    ISBN: 0-19-518524-2
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=121487
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  • 55
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    Defending Ireland : the Irish state and its enemies since 1922 (2000)
    Oxford : Oxford University Press
    Details
    Keywords: Ireland, Defenses, History, 20th century. ; Ireland, Foreign relations, 1922- ; Ireland, Military policy, History, 20th century. ; Ireland, Politics and government, 1922- ; National security, Ireland, History, 20th century.
    Pages: 382 p.
    ISBN: 0-585-48615-8
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=100313
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  • 56
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    Playing the races : ethnic caricature and American literary realism (2004)
    New York : Oxford University Press
    Details
    Keywords: United States, Ethnic relations, History, 19th century. ; United States, Race relations, History, 19th century. ; American fiction, 19th century, History and criticism. ; Caricatures and cartoons, United States, History, 19th century. ; Ethnicity in literature. ; Race in literature. ; Realism in literature. ; Stereotype (Psychology) in literature.
    Notes: Introduction: the age of caricature, the age of realism -- William Dean Howells and the touch of exaggeration which typifies -- "I want a real coon": Twain and ethnic caricature -- A Jamesian art to be cultivated -- Edith Wharton's flamboyant copy -- The "curious realism" of Charles Chesnutt
    Pages: viii, 196 p.
    ISBN: 0-19-518578-1
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=121496
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  • 57
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    The Great War and the language of modernism (2003)
    New York : Oxford University Press
    Details
    Keywords: Eliot, T. S., (Thomas Stearns),, 1888-1965, Views on war. ; Pound, Ezra,, 1885-1972, Views on war. ; Woolf, Virginia,, 1882-1941, Views on war. ; American poetry, 20th century, History and criticism. ; Americans, Great Britain, History, 20th century. ; Modernism (Literature), Great Britain. ; Modernism (Literature), United States. ; World War, 1914-1918, Great Britain, Literature and the war.
    Pages: xiii, 395 p.
    ISBN: 0-19-518055-0
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=92703
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    Consciousness lost and found : a neuropsychological exploration (2000)
    Oxford : Oxford University Press
    Details
    Keywords: Consciousness. ; Neuropsychology.
    Pages: 272 p.
    ISBN: 0-585-24486-3
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=27427
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  • 59
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    Social movements : identity, culture, and the state (2002)
    Oxford ; New York : Oxford University Press
    Details
    Keywords: Mouvements sociaux. ; Social movements.
    Notes: pt. I. Introduction. Opportunities and identities: bridge-building in the study of social movements / David S. Meyer -- pt. II. States and policies. State repression and democracy protest in three southeast Asian countries / Vincent Boudreau -- Mobilization on the South African gold mines / T. Dunbar Moodie -- Multiple meditations: the state and the women's movements in India / Manisha Desai -- The contradictions of gay ethnicity: forging identity in Vermont / Mary Bernstein -- Creating social change: lessons from the civil rights movement / Kenneth T. Andrews -- pt. III. Organization and strategies. The "meso" in social movement research / Suzanne Staggenborg -- Strategizing and the sense of context: reflections on the first two weeks of the Liverpool docks lockout, September-October 1995 / Colin Barker and Michael Lavalette -- Factions and the continuity of political challengers / Mildred A. Schwartz -- More than one feminism: organizational structure and the construction of collective identity / Jo Reger -- The development of individual identity and consciousness among movements of the left and right / Rebecca E. Klatch -- pt. IV. Collective identities, discourse, and culture. Toward a more dialogic analysis of social movement culture / Marc W. Steinberg -- Materialist feminist discourse analysis and social movement research: mapping the changing context for "community control" / Nancy A. Naples -- From the "beloved community" to "family values": religious language, symbolic repertoires, and democratic culture / Rhys H. Williams -- External political change, collective identities, and participation in social movement organizations / Belinda Robnett -- pt. V. Conclusion. Meaning and structure in social movements / Nancy Whittier
    Pages: xvi, 366 p.
    ISBN: 0-19-530277-X
    URL: http://www.netLibrary.com/urlapi.asp?action=summary&v=1&bookid=129231
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  • 60
    Electronic Resource
    Electronic Resource
    Regulation of calcium distribution in bovine sperm cells: Cytochemical evidence for motility control mechanisms (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 225-242 
    Details
    ISSN: 0886-1544
    Keywords: spermatozoa ; calcium ion transport ; motility regulation ; cholinergic agonists ; ouabain ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Behavioral responses of mature spermatozoa treated with neurotropic factors suggest that calcium entry and intracellular transport may be regulated by a cholinergic mediated program. To test the validity of this proposed mechanism, the effect of several agents on Ca distribution in the sperm cell was examined cytochemically.Sites of Ca accumulation were visualized in thin sections of bull spermatozoa by the application of a modification of Gomori's histochemical procedure for phosphatases. Intact bull sperm cells incubated at room temperature in a buffered balanced salt solution containing 5 mM/liter of CaCl2 showed small, randomly scattered deposits of the reaction product. Similarly treated sperm cells, plasmolyzed in hypoosmotic KCl, revealed a greatly increased amount of deposit associated with the cell membranes (mitochondrial surfaces and plasmalemma), the axonemal complex components, and satellite fibers adjacent to the outer dense fibers. Preincubation of intact cells in nicotine or eserine considerably enhanced the entry of calcium into the cell and its association with the membranes and other intracellular organelles. Decamethonium, an irreversible depolarizer and blocker of cholinergic receptors, interfered with the uptake and intracellular distribution of the calcium. Ouabain, the digitalis glycoside that decreases progressive motility of bull sperm and inhibits Na-, K-ATPase, appears to block Ca efflux, causing an intense accumulation of electron-opaque particles in the plasma membrane while smaller numbers of particles are distributed sparsely throughout the cell interior.The cytochemical results showing enhanced calcium entry in the presence of cholinergic agents, depressed intracellular calcium in cells treated with cholinergic receptor blocker, and intense accumulation of calcium within the cell membrane in the presence of ouabain are consistent with spermatozoan behavioral responses to these agents. These observations support the concept that neurotropic factors may be involved in regulating transmembrane and intracellular transport of ions in control of sperm cell function.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cm.970020304
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  • 61
    Electronic Resource
    Electronic Resource
    Persistence of the expression of β-tropomyosin in dystrophic avian pectoral muscle (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 309-315 
    Details
    ISSN: 0886-1544
    Keywords: tropomyosin ; avian muscular dystrophy ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The isotype pattern of tropomyosin was investigated in normal and dystrophic avian pectroal muscle using two-dimensional gel electrophoresis. Previous reports have shown that adult pectoral muscle of chickens contains only the α-subunit of tropomyosin and a breast-type troponin-T (TN-T), whereas pectoral fetal muscle contains both α- and β-tropomyosin and leg-type TN-T. The change from the fetal to the adult forms begins shortly after hatching. It has been previously reported that avian dystrophic pectoral muscle contains both the leg- and breast-type TN-T; we show that in avian dystrophic muscle there is also persistent expression of the β-subunit of tropomyosin.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cm.970020309
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  • 62
    Electronic Resource
    Electronic Resource
    Masthead (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982) 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cm.970020401
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  • 63
    Electronic Resource
    Electronic Resource
    A calcium- and pH-regulated actin binding protein from D. discoideum (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 287-308 
    Details
    ISSN: 0886-1544
    Keywords: actin-binding protein ; Dictyostelium ; cytoskeleton ; amoeboid movement ; calcium ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A protein from Dictyostelium discoideum with an apparent subunit molecular weight of 95,000 daltons (95K protein) was previously identified as an actin-binding protein ‘Hellewell and Taylor, 1979’. In this paper, we present a method for purifying the protein, and characterize some important aspects of its structure and function. Purification of the 95K protein is achieved by fractionation with ammonium sulfate followed by chromatography on DEAE-cellulose, gel filtration on 6% agarose, and final purification on hydroxyapatite. The 95K protein is a dimer, composed of apparently identical subunits. It is a rod-shaped molecule, 38 nm in length, with a Stokes radius of 74 Å. In these structural properties, the 95K protein is similar to muscle and nonmuscle α-actinins. The 95K protein and filamin are equally competent, when compared on a weight basis, to enhance the apparent viscosity of actin as determined by falling ball viscometry. The apparent viscosity of mixtures of the 95K protein and actin is dramatically reduced at pH greater than 7.0 or free ‘Ca2+’ greater than 10-7 M. We also examine the mechanism by which calcium regulates the interaction of the 95K protein and actin. A change in free ‘Ca2+’ induces no detectable change in the quaternary structure of the 95K protein. Our experiments indicate that the 95K protein does not dramatically alter the length distribution of actin filaments in the presence of micromolar free ‘Ca2+’. A large fraction of the 95K protein cosediments with actin in the presence of low free ‘Ca2+’ (ca. 3 × 10-8M), but not in the presence of high free ‘Ca2+’ (ca. 4 × 10-6M). We conclude that increased free ‘Ca2+’ inhibits gelation of actin by the 95K protein by reducing the affinity of the 95K protein for actin. We propose that 95K protein is an important component of the cytoskeletal/contractile system in D. discoideum amoebae.
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    In situ demonstration of actin in normal and injured ocular tissues using 7-nitrobenz-2-oxa-1,3-diazole phallacidin (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 343-354 
    Details
    ISSN: 0886-1544
    Keywords: NBD-phallacidin ; actin ; ocular tissues ; wound repair ; stress fibers ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The fluorescent derivative of the actin-binding toxin phallacidin, 7-nitrobenz-2-oxa-1,3 diazole phallacidin, has been used to cytologically demonstrate the presence of actin in lens epithelium, corneal endothelium, and retinal pigment epithelium. In these noninjured tissues, no stress fibers are observed and fluorescence is confined mainly to an area at or near the cell membrane, although some diffuse cytoplasmic staining can also be seen. However, following injury to either the lens epithelium or corneal endothelium of rats and frogs, stress fibers are detected, but only in those cells that migrate into the wound area. Cells on the periphery of each tissue do not partake in would repair and thus maintain their normal appearance. After the tissue has regenerated, stress fibers disappear, and those cells involved in the injury response return to their normal morphology.When rabbit corneal endothelium is placed in tissue culture, stress fibers are observed as the cells migrate away from the initial explant. Upon reaching confluency, these cells spread out and each is surrounded by thick actin-containing bands. Furthermore, they exhibit some stress cables within their cytoplasm. This is in contrast to their appearance in vivo where stress fibers are absent and fluorescence is limited to a region near the cell membrane.
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    Motility of the 6 + 0 flagellum of lecudina tuzetae (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 369-383 
    Details
    ISSN: 0886-1544
    Keywords: motility ; flagella ; cilia ; microtubules ; Gregarines ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The male gametes of the parasitic protozoan, Lecudina tuzetae, have a motile flagellum with a “6 + O” ultrastructure ‘Schrével and Besse, 1975’. These gametes were isolated from the cysts in which they develop and were observed and photographed under a variety of conditions. The flagella beat continuously, without stopping and starting, with a beat period of about 2 sec. They can beat in solutions whose viscosities are greater than 0.5 Nsm-2 (l Nsm-2 = 103 cP). The waveform can be approximated by a series of helical arcs and interconnecting straight regions that travel from the base to the tip. The helical regions have a radius of curvature of 3.2 μm and subtend a final angle of 1.7 radians. The straight portions are 2.0 μm in length. There are two sets of opposing bends, but they do not originate in the same plane. The resulting waveform is an approximately helical coil, with a pitch of 9.8 μm, a pitch angle of 0.6 radian and a peak-to-peak amplitude of 2.3 μm. The sense of the coil is left handed. The axoneme twists during beating. The main differences between the movement of this flagellum and that of typical 9 + 2 flagella are a low beat frequency and three-dimensional bends that produce relatively little forward movement of the cell. Twisting is discussed as a means of discriminating between some types of models of flagellar motility.
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    Binding stoichiometry of 21S dynein to A and B subfiber microtubules (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 429-443 
    Details
    ISSN: 0886-1544
    Keywords: 21S dynein ; tubulin ; binding stoichiometry ; ATP sensitivity ; binding cooperativity ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The binding properties of Tetrahymena 21S dynein to doublet A and B subfiber microtubules were analyzed by both a turbidimetric assay (Δ A350 nm) and electron microscopy. KCl-extracted, sucrose-gradient, purified 21S dynein binds to each of the two kinds of axonemal microtubules in both ATP-insensitive and ATP-sensitive modes, even though only a single type of binding occurs to each of the subfibers in situ. Total dynein bound to axonemal microtubules is a composite of binding that is sensitive to dissociation by ATP and binding that is insensitive to ATP. Each exhibits a different binding profile. Total binding exhibits a sigmoid profile (h = 1.93) and saturates at 1.49 mg D/mg T. ATP-sensitive binding likewise exhibits a sigmoid profile (h = 2.66) but saturates at 1.06 mg D/mg T. Binding occurs with a similar affinity for both A and B subfibers. The Hill coefficient (h) for ATP-sensitive binding implies positive cooperativity between binding events. ATP-insensitive binding was studied independently in 20 μM ATP, 10 μM vanadate, which blocks ATP-sensitive binding. ATP-insensitive binding exhibits a hyperbolic profile (h = 1.0) and likewise occurs along each of the two kinds of axonemal tubules. Binding saturates at 0.87 mg D/mg T. The binding data suggest that the tubulin dimer has conserved both ATP-sensitive and ATP-insensitive binding sites for 21S dynein, even though the sites may not be expressed in vivo.
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    Videodisc Supplement. Announcement (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. i 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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    URL: http://dx.doi.org/10.1002/cm.970020602
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    Microtubule capping structures at the tips of tracheal cilia: Evidence for their firm attachment during ciliary bend formation and the restriction of microtubule sliding (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 549-572 
    Details
    ISSN: 0886-1544
    Keywords: flagella ; cilia ; trachea ; microtubules ; crowns ; microtubule assembly ; caps ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The distal tips of the central pair and A-microtubules are capped in mammalian and avian tracheal cilia. The capping structures are similar to those found in protozoan cilia and flagella [Dentler, 1981], and consist of a central microtubule cap that links the central microtubules to the membrane or to the ciliary crown and A-microtubule plugs that insert into the lumen of each of the A-microtubule plugs is bound to the central microtubule cap by distal filaments. The ends of the central and outer doublet microtubules are tightly bound to the cap in both intact and in demembranated and reactivated tracheal cilia. Analysis of the displacement of the microtubule tips in cilia fixed at various bend angles revealed that the displacements of A-microtubules are only partially in agreement with those predicted by the sliding filament model [Satir, 1968]. These results are discussed with respect to the regulation of microtubule sliding in capped cilia and the role of the microtubule capping structures in microtubule assembly.
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    Movement and coordination of tracheal cilia and the relation of these to mucus transport (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 19-24 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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    The identification and localization of actin and actin-like filaments in lactating guinea pig mammary gland alveolar cells (1981)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 1 (1981), S. 329-347 
    Details
    ISSN: 0886-1544
    Keywords: actin ; microfilaments ; heavy meromyosin ; mammary gland ; secretion ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Cytochalasin B, a microfilament-altering drug, inhibits lactose synthesis in lactating guinea pig mammary gland [Biochim. Biophys. Acta 392:20, 1975] but not primarily by inhibiting glucose transport [Eur. J. Cell Biol. 20:150, 1979]. In order to study the possible role of microfilaments in lactose synthesis and secretion, we isolated both the alveolar (milk-secreting) and myoepithelial (contractile) cells from lactating mammary gland. Light microscopy shows that the alveolar cell fraction (viability approximately 71%) is homogenous and that the cells retain strong polarity of secretory structures in the apical region. Two proteins were extracted from the alveolar cell fraction. One (mol wt 42,000) comigrates with skeletal muscle actin on SDS-PAGE gels. The other, a high-molecular-weight (180,000) protein (HMWP) may be analogous to actin-binding protein or clathrin. An extract from the myoepithelial cell fraction also contains a protein that comigrates with actin but no HMWP. Whole tissue extract contains the 42K protein, and a 185K HMWP. Examination of the alveolar cell extract by electron microscopic (EM) negative staining revealed meshworks of multistranded, interconnecting filaments, with attached globular structures (100-200 A) (possibly the HMWP) and single filaments (40-60 A diameter) branching off. To localize these filamentous structures in situ, whole tissue was glycerinated and incubated with rabbit skeletal muscle heavy meromyosin (HMM). Masses of filaments in myoepithelial cells served as convenient standards for HMM decoration. Decorated filaments have cross-arms or projections, unlike the narrow, smooth filaments of control tissue. Decorated filaments in alveolar cells are located beneath the plasma membrane, in close association with secretory vacuoles, and near the Golgi apparatus; filaments near the latter two are often oriented perpendicular to the plasma membrane. Microvesicles are embedded in meshworks under the plasmalemma and near the Golgi apparatus. Intermediate-sized (85-115 A diameter), non-decorated filaments diverge from the meshworks of decorated filaments. Microvesicles are associated with intermediate-sized filaments as well. The association of actin-like filaments with secretory vacuoles and microvesicles and their location in areas of the cell concerned with biosynthetic activities suggest a possible function in the intracellular transport of secretory products.
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    Motility of 9 + 0 mutants of Chlamydomonas rheinhardtii (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 165-168 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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    Role of calmodulin in the flagellar axoneme: Effect of phenothiazines on reactivated axonemes of Chlamydomonas (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 199-204 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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    Serum complement (C'3a and C'5)-induced inhibition of rabbit tracheal cilia (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 71-75 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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    Invited review: Bacterial flagellar sheaths: Structures in search of a function (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 93-103 
    Details
    ISSN: 0886-1544
    Keywords: bacterial motility ; flagella ; sheathed flagella ; complex flagella ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Although bacterial flagellar sheaths were observed over 30 years ago, they may still be characterized as structures in search of a function. In addition to true sheaths, bacterial flagella may possess other adornments that cause an increase in the organelle's cross-sectional diameter. These “complex flagella” are sharply differentiated from sheathed flagella. Immunological and chemical distinctions have been found between flagellar sheaths, flagellar cores, and LPS layers inferred to be the sheath sensu stricto. Although complex flagella may serve as specific receptors for flagellotropic phages or in allowing for more efficient swimming in viscous environments, similar functions have not yet been attributed to true sheaths. It is postulated that flagellar sheaths may allow for specific interaction between a bacterium and a surface. In addition, there is a problem as to the relationship between a rapidly rotating flagellum and the sheath.
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    Coelomocyte motility (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 113-121 
    Details
    ISSN: 0886-1544
    Keywords: coelomocytes ; filopodia ; whole cell translocation ; video microscopy ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: We have utilized a video-enhanced contrast system coupled to a DIC-equipped microscope to examine the motility of both whole coelomocytes and individual filopodia. When the cells are left in diluted coelomic fluid, they exhibit a fibroblast-like mode of translocation across the substrate. These cells extend lamellipodia at their advancing margin and develop retraction fibers at the trailing edge. Filopodia are actively extended from the lamellipodia of the advancing margin. Cells that are washed free of the coelomic fluid and placed in an isotonic buffer lose their ability to translocate. Filopodia on these stationary cells are seen to undergo a series of waving and bending motions. These motions are rapid and result in a filopodium folding back upon itself only to reextend later. Both forms of motility are discussed in light of the existing structural and biochemical knowledge of this and other cell types.
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    Quantitative studies on polarization optical properties of living cells III: Cortical birefringence of the dividing sea urchin egg (1981)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 1 (1981), S. 387-397 
    Details
    ISSN: 0886-1544
    Keywords: birefringence ; polarizing microscope ; sea urchin egg ; cortex ; mitosis ; cleavage ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Birefringence (BR) at the cell surface of fertilized eggs of the sand-dollar, Clypeaster japonicus, during mitosis and cleavage was determined with a photoelectric BR detection apparatus [Hiramoto et al, 1981a]. The cortex of about 2 μm thickness is birefringent positive with respect to the normal to the cell surface. The hyaline layer is negatively birefringent. The halo-layer consisting of a row of microvilli surrounding the egg is positively birefringent in normal Ca-free sea water, while it is negatively birefringent in Ca-free sea water with high refractive index. The BR of the cortex gradually increases over the entire surface during mitosis until the onset of cleavage. The BR of the cortex at the polar region reaches a maximum shortly after the onset of cleavage and then decreases, while the BR of the cortex at the equatorial region begins to decrease shortly before the onset of cleavage, reaches a minimum shortly after the cleavage starts, and then increases again as the cleavage furrow advances. The coefficient of birefringence of the cortex is about 2.5 × 10-5 at the maximum. The BR change of the cortex during mitosis and cleavage is interpreted as a passive deformation caused by the constriction of the contractile ring as well as an active structural change of the cortex occurring in the dividing cell.
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    Microtubule-containing detergent-extracted cytoskeletons in sea urchin eggs from fertilization through cell division: Antitubulin immunofluorescence microscopy (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 213-226 
    Details
    ISSN: 0886-1544
    Keywords: microtubules ; fertilization ; cell division ; sea urchin ; cytoskeleton ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The microtubule-containing structures that appear in eggs during fertilization and cell division in the sea urchins Lytechinus variegatus and Arbacia punctulata were detected by antitubulin immunofluorescence microscopy of detergent extracted cytoskeletal preparations. The extraction buffer, which is composed of 0.55 mM MgCl2, 10 mM EGTA, 25 mM MES, 25% glycerol, 1% Nonidet P-40, and 25 μM PMSF, pH 6.7, allows for dramatically improved fluorescent images compared to those obtained using conventional staining procedures, with residual background staining being reduced to near zero.The immunofluorescent images obtained using this technique provide information on several motile events that occur during the first cell cycle. This technique demonstrates that all of the cytoplasmic microtubules are associated with the incorporated sperm's centrioles during female pronuclear migration. This changes during the centration of the male and female pronuclei at which time a monastral array of microtubules forms in the egg's cytoplasm. A large proportion of the monastral microtubules do not appear to be associated with the centrioles. At prophase and early metaphase, the centrioles are the dominant microtubule organizing centers (MTOCs) consistent with mitotic theories that the kinetochore catches, but does not initiate, microtubules. Observations of intercentriolar distances show that there are three stages of pole separation during the first cell cycle. The initial separation occurs during pronuclear centration, the second during the streak stage, and the final one during the late stages of mitosis. At telophase, polar microtubules appear to extend into the cortex supporting the cell surface at all regions except the presumptive cleavage site.
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    Masthead (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983) 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cm.970030401
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    Characterization of the chlamydomonas flagellar collar (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 273-280 
    Details
    ISSN: 0886-1544
    Keywords: Chlamydomonas flagellar collars ; Chlamydomonas cell wall ; mating in Chlamydomonas ; cell wall proteins ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The flagella of Chlamydomonas reinhardtii protrude through the cell wall via short, tunnel-like openings that are lined with 11 nm × 500 nm fibers arranged in parallel array. These cylindrical collections of fibers presumably permit free movement of the flagella within the cell wall. In this report electron-microscopic evidence is presented showing that during the initial stages of the mating reaction intact collars slip off of the ends of the flagella when cell wall loss occurs. Electrophoretic analysis of isolated collars reveals one major protein and several minor species.
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    Crawling caenorhabditis elegans spermatozoa contact the substrate only by their pseudopods and contain 2-nm filaments (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 333-347 
    Details
    ISSN: 0886-1544
    Keywords: Caenorhabditis elegans spermatozoa ; cell motility ; electron microscopy ; cell-substrate contact ; 2-nm filaments ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The locomotion of C. elegans spermatozoa resembles, in many respects, the crawling movements of other eukaryotic cells. However, these sperm contain surprising little actin, which plays no apparent role in this cell's motility. Electron microscopy has revealed that crawling spermatozoa retain a strict morphological polarity so that the organelle-filled cell body is separated from the pseudopod by an array of cytoplasmic laminar membranes. When sperm crawl only the pseudopod contacts the substrate; the cell body is either pulled behind or carried on top of the rear portion of the pseudopod. Fingerlike projections which extend forward from the leading edge of the pseudopod initiate contact with the substrate. The underside of the pseudopod exhibits areas of close (40 nm separation) membrane-substrate association with intervening areas of wide (up to 300 nm) membrane-substrate gaps. The pseudopod cytoplasm contains 2-nm filaments but no filamentous actin has been observed. These 2-nm filaments were detected in thin sections of crawling cells and in negative-stained remnants of spermatozoa disrupted by either hypotonic buffer on Triton X-100. The filaments are found both free in the cytoplasm and closely associated with the cytoplasmic face of the plasma membrane and are usually oriented along the long axis of the cell. Neither the identity nor the function of these filaments has been established although their location and orientation suggest that they may be involved in generating propulsion.
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    Changes in cytoskeletal proteins of polymorphonuclear leukocytes induced by chemotactic peptides (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 349-361 
    Details
    ISSN: 0886-1544
    Keywords: myosin phosphorylation ; actin polymerization ; chemotactic factors ; leukocytes ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Changes in the state of polymerization of actin and phosphorylation of myosin have been observed in polymorphonuclear leukocytes (PMNs) soon after the addition of the chemotactic peptide N-formylnorleucylleucylphenylalanine. At a time when the cells are observed to extend many ruffles or lamellipodia from their surface, the fraction of the cellular actin present in a monomeric form is decreased by about 25% as assayed by the ability of the G-actin to inhibit DNAase. These changes are temporally correlated with an increase in the staining by nitrobenzooxadiazole (NBD)-phallacidin, a probe that binds F-actin selectively. The NBD-phallacidin staining is observed in the surface ruffles. When the peptide concentration is decreased by addition of a tenfold excess of buffer, cells withdraw their surface ruffles and form blebs. These changes correlate with an increase in the G-actin levels detected with the DNAase inhibition assay. An increase in phosphorylation of the 20,000-dalton light chain of myosin is also observed in leukocytes stimulated by addition of chemotactic peptide. These observations of changes in cytoskeletal proteins of PMNs provide a beginning for further studies on the regulation of cell motility by chemotactic factors.
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    Organization and function of structural elements in focal contacts of tissue culture cells (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 391-397 
    Details
    ISSN: 0886-1544
    Keywords: focal contacts ; microfilaments ; microinjection ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The role of structural elements in the organization and maintenance of focal contacts was studied by microinjecting into tissue culture cells specific probes which interfere with filamentous actin or with vinculin: actin interaction. Injection of actin capping proteins from Physarum and brain resulted in breakdown of microfilament bundles starting at their distal ends and in loss of focal contacts. This process was fully reversible. Injection of a high affinity antibody against chicken gizzard vinculin led to partial breakdown of microfilament bundles concomitant with disruption of focal contacts with vinculin remaining at the plasma membrane. This process was irreversible.
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    Structural connections of the muscle-tendon junction (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 431-438 
    Details
    ISSN: 0886-1544
    Keywords: myotendinous junction ; laminin ; type IV collagen ; heparan sulfate proteoglycan ; alpha actinin ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The muscle-tendon junction of murine skeletal muscles has been analyzed by a variety of extraction techniques, by myosin subfragment-1 binding experiments, and by ultrastructural immunocytochemistry. The results indicate that the muscle-tendon junction is composed of four distinct domains: an intracellular domain, the internal lamina; a domain connecting the internal lamina with the lamina densa of the external lamina, the connecting domain; the lamina densa; and a domain which attaches the lamina densa to the collagen fibers, the matrix. Each of these domains is distinct with respect to position, three-dimensional organization, and molecular composition, and is therefore considered to have a unique role in the transmission of contractile force.
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    URL: http://dx.doi.org/10.1002/cm.970030511
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    A covalently cross-linked matrix in skeletal muscle fibers (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 463-483 
    Details
    ISSN: 0886-1544
    Keywords: intracellular matrix ; extracellular matrix ; covalently cross-linked matrix ; ε-(γ-glutamic) lysine bonds ; skeletal muscle ; titin ; covalently cross-linked collagen ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: When skeletal, cardiac, and smooth muscle is exhaustively extracted with a protein-unfolding reagent such as 6 M guanidine HCl and a disulfide-reducing reagent such as 5% β-mercaptoethanol, a tissue ghost remains intact and retains the characteristic shape and dimensions of the tissue before extraction. In the case of chicken pectoral muscle, the tissue ghost contains 1% of the original muscle proteins. Guanidine HCl extraction followed by collagenase treatment of glycerol-extracted chicken pectoral muscle releases a clean preparation of elongated structures containing 0.2% of the original protein and representing the covalently cross-linked remnants of the muscle fibers. The material of these muscle fiber ghosts extends throughout the interior of the cell. Antibodies raised against the tissue ghosts of smooth muscle cross-react with glycerol extracted skeletal myofibrils, forming a banding pattern which coincides with the banding pattern observed when myofibrils are reacted with antibodies against titin. Titin, a large and soluble protein found in skeletal muscle, cross-reacts with our antigizzard antibody. However, amino acid analysis of the muscle fiber ghosts indicates that titin cannot be the only subunit of the insoluble polymer, but that one or more proteins with a very high glycine and alanine content and a very low basic and acidic amino acid content must also form part of the covalently cross-linked matrix. The possibility is presented that this matrix may be the basis of the superthin 2-3-nm filaments which have been observed in a variety of cell types.
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    URL: http://dx.doi.org/10.1002/cm.970030514
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    Actin-mediated surface motility during sea urchin fertilization (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 513-524 
    Details
    ISSN: 0886-1544
    Keywords: fertilization ; actin ; microfilaments ; sea urchin ; cell division ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The sea urchin egg at fertilization is an ideal model in which to study actin-mediated surface activity. Electron microscopy of unfertilized eggs demonstrates the presence of thousands of well-arrayed short microvilli, which appear supported by cytochalasin-sensitive actin oligomers as detected with rhodamine-labeled phalloidin staining of permeabilized eggs. At insemination, the previously short microvilli elongate and cluster around the successful sperm during incorporation. Phalloidin staining demonstrates a tremendous recruitement of polymerized actin into the site of sperm incorporation, resulting in the formation of the fertilization cone. Fertilization of cytochalasin-treated eggs results in the normal activation of the metabolic and bioeletric events, but sperm incorporation does not occur since the localized actin assembly required for fertilization cone formation is precluded. After sperm incorporation, the entire fertilized surface is restructured, as a result of a massive polymerization of actin to produce a burst in microvillar elongation. Addition of cytochalasin to eggs immediately following sperm incorporation demonstrates the recruitment of actin assembly for the proper progression through the first cell cycle. During normal cell divison, the egg surface retains the long microvilli. The furrow which forms at cytokinesis does not appear as a unique new structure, but rather as a reorganization of the cortical microfilaments. Quantitative fluorescence microscopy argues against an increase in microfilaments during early cytokinesis. At the latest stages of cytokinesis, a thickening of the cortical actin is noted, which could possibly be interpreted as a contractile ring. A minor basal level of actin assembly with numerous nucleation sites in unfertilized eggs and a tremendous but localized assembly of microfilaments surrounding the sperm during incorporation, followed by a massive global microfilament assembly event to elongate the fertilized egg microvilli resulting later in the reorganization of these microfilaments to produce the forces necessary for cytokinesis, highlight the utility of the study of sea urchin eggs at fertilization for understanding actin-membrane interactions.
    Additional Material: 13 Ill.
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    URL: http://dx.doi.org/10.1002/cm.970030518
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    Cell surface and cytoskeletal interactions in a temperature-sensitive strain of SV40-transformed mouse fibroblasts (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 553-565 
    Details
    ISSN: 0886-1544
    Keywords: microfilaments ; cytoskeleton ; simian virus 40 ; cell adhesion ; cell surface ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In order to assess the role of cytoskeletal structure in modulating cell surface topography during cell transformation, cytoskeletal organization of 3T3 mouse cells transformed with a tsA mutant of simian virus 40 (SV40) was studied in detail by correlative light and electron microscopy. Detergent-extracted, criticalpoint dried whole cells observed in the electron microscope were seen to contain well-organized microfilament bundles (stress fibers) traversing the longitudinal axis of cells grown at the restrictive temperature (39°C). When grown at the permissive temperature (32°C), cells prepared in this manner were not observed to contain such structures. However, when semithin sections (0.5 μm) were viewed by transmission electron microscopy at 120 kV, short microfilament bundles were seen in 32°C-grown cells. There was an alteration in the morphology of these structures at sites of attachment to the substratum (focal contacts), and they were shorter in length than microfilament bundles of 39°C-grown cells. A difference was also observed between the two phenotypes in the layer of microfilaments associated with the dorsal cell surface. Since it is this layer that directly determines cell surface architecture, it is proposed that changes in microfilament bundle-generated surface tension are responsible for alterations of this layer, leading to an altered cell surface morphology. Tension may be modified by disturbances in focal contacts (or adjacent regions) or altered actin-associated protein(s).
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    URL: http://dx.doi.org/10.1002/cm.970030522
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    Effects of abnormal cytoskeletal structure on erythrocyte membrane mechanical properties (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 609-622 
    Details
    ISSN: 0886-1544
    Keywords: erythrocyte membrane ; surface elastic shear modulus ; membrane viscosity ; hereditary disorders of blood ; membrane yield ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Measurements of the mechanical properties of the erythrocyte membrane provide a direct assessment of the proper function of its structural components. To assess the effects of alterations in molecular structure on membrane mechanical properties, measurements have been performed on cells from six individuals whose membranes contain inherited, biochemically characterized structural defects. Because the contribution of the memmbrane skeleton to the mechanical behavior of the membrane is most evident in shear deformation, mechanical experiments were performed to measure the material constants which characterize the response of the membrane to shear force resultants. The surface elastic shear modulus characterizes the elastic response of the membrane; the yield shear resultant is the maximum shear force resultant which the membrane can support elastically; and the plastic viscosity coefficient characterizes the rate of membrane deformation when the elastic limit has been exceeded.Generally, it was found that when the molecular defect is found to occur in a region of the skeleton which is stress-supporting, the maximum elastic strength of the membrane is reduced. However, the magnitude of the reduction can be quite different for membranes having similar or even identical defects. In some cases the differences can be attributed to the removal of the most fragile cells of the population by the spleen, but other results indicate that the biochemical description of the defects may be incomplete. These results emphasize the need for further refinements both in the biochemical characterization of membrane skeleton structure and in the description and measurement of membrane mechanical properties.
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    URL: http://dx.doi.org/10.1002/cm.970030526
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    Effects of folic acid upon filopodia of Dictyostelium discoideum vegetative amoebae (1984)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 4 (1984), S. 129-135 
    Details
    ISSN: 0886-1544
    Keywords: amoeboid motion ; chemoattractants ; chemotaxis ; Dictyostelium ; filopodia ; folic acid ; pterins ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Living vegetative D. discoideum amoebae were studied to determine whether their filopodia respond to folic acid, a chemoattractant for these cells. Exponentially growing amoebae (ca. 10 μm diameter) exhibit 5-30 μm long filopodia; at stationary phase, aggregation competent amoebae have numerous multibranched filopodia up to 100 μm long. Folic acid was observed to stimulate production, elongation, and branching of filopodia with its effects progressively changing as the amoebae approach aggregation. Filopodial construction was also found to be dependent upon Mg2+ levels. The significance of these results is discussed with respect to progressive changes within the vegetative phase as well as to the mechanisms of amoeboid movement, pseudopodial activity, and chemotaxis.
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    URL: http://dx.doi.org/10.1002/cm.970040206
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    Intracellular movement of fodrin (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 649-655 
    Details
    ISSN: 0886-1544
    Keywords: axonal transport ; lymphocyte capping ; spectrin ; fodrin ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Fodrin is an actin/calmodulin-binding protein with similarities to spectrin (erythrocytes) and TW 260/240 (brush border). It is concentrated beneath the plasma membranes of neurons and other cells. We have observed translocations of fodrin in both neurons and lymphocytes. Newly synthesized, radiolabeled fodrin moves down axons at a maximum velocity (about 50 mm/day) that is slower than the most rapidly axonally transported proteins (group I). A portion of fodrin appears to move more slowly at velocities (1-10 mm/day) resembling those of actin and myosin (group IV) and tubulin and neurofilament proteins (group V). In lymphocytes, when certain surface antigens are induced by cross-linking agents to migrate to one pole of the cell and form a cap, fodrin redistributes beneath the membrane and forms a subcap. The movements of fodrin in lympohocyte capping and in the axonal transport of group IV polypeptides have certain similarities. In both cases, the redistribution of fodrin is accompanied by concomitant redistributions of actin, myosin, and calmodulin, and both processes proceed at similar velocities. We consider the possibilities that these two processes are related, both being driven by a submembrane force-generating system comprising in part actin, myosin, and fodrin, and that fodrin serves to link various organelles or proteins to this system.
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    URL: http://dx.doi.org/10.1002/cm.970030529
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    A quantitative comparison of cellular motile systems (1984)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 4 (1984), S. 1-5 
    Details
    ISSN: 0886-1544
    Keywords: motility ; power output ; muscle ; flagella ; cytokinetic furrow ; mitotic spindle ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Cellular motile systems as diverse as muscle and the mitotic spindle have been compared by their specific power output: the maximum power they develop per unit of engine volume. Striated muscles and flagella have high specific output; their performance is comparable to that of typical automobile engines. The cytokinetic furrow and the mitotic spindle have very much lower specific power output. The furrow's output is 7,000 times lower than muscle and the spindle's is 300,000 times lower. Different macromolecules have been used to generate power in systems with similar output (muscles and flagella) and, conversely, the same macromolecular motor has been used in systems with very different output (muscles and cytokinetic furrows). The common feature amid this diversity is adaptation to a particular biological role, which specific power output reflects very well. High values are found where a powerful, compact engine should be advantageous, while low values are found where precision, not power, matters most.
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    Announcement (1984)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 4 (1984), S. 76-76 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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    URL: http://dx.doi.org/10.1002/cm.970040108
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    Coupling of photomovement and photosynthesis in desmids (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 73-82 
    Details
    ISSN: 0886-1544
    Keywords: desmids ; videomicrography ; photokinesis ; photophobic response ; photophosphorylation ; photosynthesis ; phototaxis ; uncouplers ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The effects of the uncouplers CCCP and DNP on photokinesis, phototaxis, and the photophobic response in the desmid Cosmarium have been studied both in population systems and by videomicrographic, single-cell analysis. Light-dependent motility is specifically inhibited by both uncouplers, indicating that photokinesis is driven by photophosphorylation. In population experiments, phototaxis and accumulations in light traps due to photophobic responses are inhibited by drug concentrations comparable to those that inhibit photokinesis. Analysis of single-cell behavior demonstrated, however, that neither photophobic responses elicited by an increase in light intensity (step-up response) nor by a decrease (stepdown response) are inhibited, as long as the reduced motility allows the organisms to cross a light--dark border. Phototactic orientation is not impaired by DNP in the single cell analysis, but CCCP significantly reduced the degree of orientation. The results indicate that, although chlorophyll is the photoreceptor for all three photoresponses, at least the photophobic response is independent of both the photosynthetic electron transport chain and photophosphorylation.
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    Instructions for contributors (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 91-92 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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    URL: http://dx.doi.org/10.1002/cm.970020108
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    Masthead (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982) 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cm.970020201
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    A motile system of singlet microtubules in spermatozoa (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 93-101 
    Details
    ISSN: 0886-1544
    Keywords: cell motility ; singlet microtubules ; dynein ; coccid insect ; aflagellate spermatozoa ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In this report we demonstrate that in the coccid insects Pseudococcus, Phenacoccus, and Planococcus the whole spermatozoon is made up by a nuclear central core surrounded by two complete and one incomplete turns of concentric microtubule palisades. Microtubules of the outer row are linked by a system of short projections 6 nm long; those of the inner row are linked to each other by similar arms; a second system of 6 nm arms links the tubules of each inner row to those of the respective outer row. All these systems of arms are longitudinally spaced every ∼ 12 nm. The motility of this spermatozoon is due to waves progressing from the posterior extremity to the anterior one. By SDS polyacrylamide gel electrophoresis a group of high molecular weight polypeptides is detected, one of which migrates in coincidence with the A dynein band from sea urchin sperm. Our data suggest that occurrence in coccid spermatozoon of a motility due to singlet tubules-dynein interaction.
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    Effects of phalloidin microinjection and localization of fluorescein-labeled phalloidin in living sand dollar eggs (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 103-113 
    Details
    ISSN: 0886-1544
    Keywords: actin ; cleavage ; fluorescein-labeled phalloidin ; microinjection ; phalloidin ; sand dollar eggs ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Effects of microinjection of phalloidin on fertilization and cleavage of sand dollar (Clypeaster japonicus and Scaphechinus mirabilis) eggs were studied. The drug, previously injected into unfertilized eggs, showed no effect on the elevation of the fertilization membrane upon insemination up to an intracellular concentration of 50 μM. However, the movement of the egg pronucleus to the sperm pronucleus was inhibited and the fusion of pronuclei did not occur. The subsequent development no longer took place. When phalloidin was injected into fertilized eggs, the thickness of the cortical layer increased and the microvilli became conspicuous. Both nuclear division and cleavage were inhibited at the intracellular concentration of more than 20 μM, though the latter seemed to be more sensitive to phalloidin than the former.Fluorescein-labeled phalloidin (FL-phalloidin) was injected into eggs in order to investigate F-actin localization by fluorescence microscopy. In both unfertilized and fertilized eggs, FL-phalloidin was localized in the cortical layer within 1 min after injection. It was also localized in the cortical layer as radially oriented rodlike structures when injected into fertilized eggs before the disappearance of the nuclear membrane. No distinct fluorescence was detected in the mitotic apparatus or in the cleavage furrow. FL-phalloidin redistributed gradually into egg cytoplasm. In unfertilized eggs, fluorescent rods were found especially in the egg pronucleus 30 min after injection.
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    Tomato actin and myosin: Contractile proteins from a higher land plant (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 131-147 
    Details
    ISSN: 0886-1544
    Keywords: higher land plant contractile system ; actin activation of myosin ; S-1 decoration of actin ; polymerization of actin ; calcium sensitivity of actomyosin interaction ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This paper describes the initial isolation of actin- and myosin-like proteins from the cytoplasm of the endocarp tissue cells of the fruit of the tomato, Lycopersicon esculentum. Low ionic strength buffers extracted the 42,000 molecular weight tomato actin in the depolymerized form. Tomato actin can be polymerized in 0.1 M KCl, 2 mM MgCl2 to form 6 nm diameter filaments resembling rabbit skeletal muscle F-actin in their ultrastructure and pattern of decoration with rabbit myosin subfragment-1 (S-1). Tomato F-actin activates the low ionic strength Mg2+ ATPase of rabbit S-1 up to ten-fold. High ionic strength extracts of tomato yield a myosinlike enzyme whose ATPase activity in 0.5 M KCl is maximal in the presence of K+-EDTA and is repressed in the presence of Mg2+. The column-purified enzyme forms a complex with rabbit F-actin, which can be dissociated by Mg2+ ATP. The low ionic strength Mg2+ ATPase of tomato myosin can be activated ten-fold by rabbit actin and up to nineteen-fold by tomato actin. No activation of the tomato myosin by rabbit F-actin occurs in the absence of free calcium ions.
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    Cell locomotion in vitro by Xenopus laevis gastrula mesodermal cells (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 149-161 
    Details
    ISSN: 0886-1544
    Keywords: cell locomotion ; gastrulation ; contact paralysis ; collagen substratum ; serum factors ; morphogenetic movements ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Prospective mesodermal cells of Xenopus laevis gastrulae showed substantial locomotion in vitro, averaging 4.3 μM/min, when dissociated and cultured on a glass surface coated with collagen and fetal bovine serum. The cell translocate by making lamellipodia and filopodia whereas the main cell body remains rounded. When two mesodermal cells made contact with each other, they showed contact paralysis of lamellipodial activity. In contrast, when mesodermal cells contact ectodermal cells, contact paralysis does not occur. Rather, migrating mesodermal cells continue to translocate. The locomotion in vitro appears to mimic that in vivo during gastrulation, because of the similarities of the rate of movement and the cell shape in culture and in embryos. Neither prospective ectodermal cells from gastrulae nor prospective mesodermal cells from blastulae showed locomotion under the same culture conditions.
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    Abstracts (1982)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 191-194 
    Details
    ISSN: 0886-1544
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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    URL: http://dx.doi.org/10.1002/cm.970020736
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    Ciliary but not saltatory movements are inhibited by vanadate microinjected into living cultured cells (1983)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 3 (1983), S. 167-184 
    Details
    ISSN: 0886-1544
    Keywords: saltatory organelle movements ; ciliary movement ; dynein ; vanadate ; microinjection ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: To test the idea that saltatory organelle movements of nonmuscle cells might be driven by microtubule-dynein interactions, we microinjected vanadate into several different types of cultured cell. Solutions of sodium metavanadate made up in a simple buffered salt solution were pressure microinjected into fully spread cells in an open-topped culture chamber placed on the stage of an inverted microscope. The cells were observed by oil-immersion phase-contrast optics and results were recorded on movie film. Vanadate, at 10-5-10-2 M, microinjected into cultured chick embryo fibroblasts, failed to inhibit organelle movements. To test the effectiveness of vanadate's inhibitory action under living cell conditions, ciliated epithelial cells were micro-injected. In these cells even the smallest microinjection of 5 × 10-5 M vanadate caused an immediate cessation of ciliary beating. Moreover, in cells that were well spread it was found that whereas vanadate, at 5 × 10-5 × 10-3M, inhibited ciliary motion, it failed to inhibit organelle saltations in the same cell. To determine whether vanadate would inhibit a living actin-myosin system, myocardial cells were also microinjected. Following microinjection of 5 × 10-5 and 5 × 10-4M vanadate a temporary tonic contraction (which also occurred following microinjection of buffer alone) was followed by regular beating. Taken together these results demonstrate that in living cell systems microtubule-dynein interactions are as sensitive to vanadate inhibition as they are in demembranated model systems, and that a working actin-myosin system in a living muscle cell does not share this great sensitivity. In light of the pronounced differential inhibitory effects of vanadate on the movements of cilia and organelles, our results suggest that saltatory organelle movements in chick embryo fibroblasts and rabbit oviduct epithelial cells are unlikely to be brought about by microtubule-dynein interactions.
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