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  • Books  (121)
  • inflammation  (121)
  • MDPI - Multidisciplinary Digital Publishing Institute  (121)
  • 2020-2024  (121)
  • 2020-2023
  • 2022  (121)
  • 2022  (121)
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  • Books  (121)
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  • 2020-2024  (121)
  • 2020-2023
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  • 1
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    Nutraceuticals and Human Health (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-04-01
    Description: In this Special Issue, we have published papers on the health-promoting effects of nutraceuticals from different sources, and their effects in different pathologies. Extracts from plants have been analyzed, for example, extracts from olive leaves, Mikania micrantha, the devil’s claw, raspberries and others, alongside marine phytoplankton, egg-yolk and marketed dietary supplements. The effects of these extracts and dietary supplements have been studied in diseases associated with obesity, and in diseases where inflammation pathways are involved. The effectiveness of resveratrol and curcumin to support the anticancer activity of cisplatin has also been reported, as well as the ability of devil’s claw root extract to stimulate the CB2 receptors in synoviocytes in osteoarthritis patients. The anti-oxidant effect of marine phytoplankton has been studied on muscle damage, both in humans and in an animal model, and the effects of the metabolite of antocianin were analyzed in a mouse model of amyotrophic lateral sclerosis. Finally, reviews on the use of lactoferrin, ω3 and ω6 and abscisic acid have been reported, in addition to the crosstalk between prostate cancer and microbiota inflammation. Although it is not yet possible to draw definitive conclusions on the use of nutraceuticals, several mechanisms of action for many of them have been further clarified.
    Keywords: fertility ; ingredients ; male reproduction ; semen parameters ; supplements ; allithiamine ; garlic ; hyperglycaemia ; advanced glycation end-products ; cytokines ; abscisic acid ; prediabetes ; type 2 diabetes mellitus ; metabolic syndrome ; insulin resistance ; adipocyte browning ; AMP-activated protein kinase ; food supplement ; frambinone ; meal frequency ; open-field test ; elevated plus maze ; sensory motor gating ; pre-pulse inhibition ; c-Fos ; amyotrophic lateral sclerosis ; anti-inflammatory ; antioxidant ; phenolic acid ; neuroprotective ; neurodegeneration ; obesity ; overweight ; beta-glucans ; chitosan ; follow up study ; weight loss programs ; weight gain ; weight loss ; body weight changes ; phytoplankton ; antioxidants ; muscle damage ; muscle recovery ; muscle soreness ; Viburnum opulus ; phenolic compounds ; adipogenesis ; PPARγ ; lipase inhibition ; green tea ; epigallocatechin ; lipid profile ; high-fat diet ; fast food ; osteoarthritis ; nutraceuticals ; polyphenols ; volatile compounds ; β-caryophyllene ; eugenol ; FAAH ; cannabinoid receptors ; phospholipases ; lactoferrin ; bovine milk ; nutraceutical ; human health ; resveratrol ; curcumin ; cisplatin ; head and neck cancer ; cell cycle ; apoptosis ; prostate cancer ; microbiota ; nutraceutical compounds ; fecundation ; inflammation ; cytokine ; growth factors ; metabolomics ; lipidomics ; ω-3PUFAs ; ω-6PUFAs ; endocannabinoids ; CRC ; fatty acids ; Gymnema inodorum ; gymnemic acid ; Mikania micrantha ; anti-hypercholesterolemia ; steatosis ; olive leaf ; macrophages ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
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  • 2
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    Research Topics in Medicines and How Our Board Members Are Engaged in Them (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2022-06-21
    Description: With the development of analytical instruments, the academic system has become more complicated, producing new journals one after another. Therefore, it became much important to clarify what is original of “Medicines”. As the name Medicines indicates, it includes science and practice of caring for a patient and managing the diagnosis, prognosis, prevention, treatment or palliation of their injury or disease. Therefore, Medicines differs from other journals with similar title in that it covers a wide range of fields, from traditional medicine to rapidly developing molecular-targeted drugs, focusing on their pharmacological effects, structure–activity relationships, metabolic pathways, gene expression, using cultured cells, animals, and clinical trials. Most parts of this Special Issue were written by our editorial board members, who described the research topics and how they are engaged in their field of research. All of these articles are their life-long story. We collected a total number of 22 original works by basic researchers and clinical doctors. We hope that readers can get a chance to know the current status of diverse fields of medicines, and what your most important research themes are after reading these articles.
    Keywords: Hedychium ; traditional medicine ; coronarin D ; villosin ; anti-acetylcholinesterase ; antidiabetic ; anti-inflammatory ; antimicrobial ; antioxidant ; antitumor ; Genista tridentata ; Pterospartum tridentatum ; isoflavones ; flavonols ; genistein ; biochanin A ; rutin ; daidzein ; inflammatory bowel disease ; Crohn’s disease ; ulcerative colitis ; extra-intestinal manifestations ; orofacial granulomatosis ; tag-like lesions ; cobblestoning ; mucogingivitis ; lip swelling ; aphthous stomatitis ; Angelicae Sinensis Radix ; Danggui ; granules ; herb ; multivariate analysis ; ultra-performance liquid chromatography ; Tai Chi ; qigong ; immune system ; immunity ; inflammation ; telemedicine ; remote monitoring ; GER-e-TEC ; elderly patient ; artificial intelligence ; geriatric syndromes ; detection of the precursory signs of decompensation of geriatric syndromes ; renal cell cancer ; genomic landscape ; targeted therapy ; tumor evolution ; tumor heterogeneity ; allergic rhinitis ; quercetin ; human CD4+ T cells ; Th1/Th2 cytokine balance ; modulation ; in vitro ; intravascular catheter ; CRBSI ; biofilm ; CVC ; antifouling ; chromone ; tumor specificity ; QSAR analysis ; apoptosis ; cell cycle analysis ; contrast-enhanced ultrasound ; hepatocellular carcinoma ; LI-RADS ; chronic liver disease ; granuloma annulare ; granulomatous disorders of the skin ; inflammatory skin conditions ; medical dermatology ; biliary tract cancer ; cholangiocarcinoma ; PARP ; BRCA ; olaparib ; rucaparib ; liver cancer ; pancreatic adenocarcinoma ; pancreatic cancer ; sarcoidosis ; superior vena cava syndrome ; venous thrombosis ; RUCAM ; Roussel Uclaf Causality Assessment Method ; diagnostic algorithm ; iDILI ; iDrug induced liver injury ; DILI ; HILI ; herb induced liver injury ; Stachys L. ; traditional uses ; pharmacological activities ; phytochemicals ; bioactive compounds ; Kampo formulae ; alkaline extract of Sasa sp. ; pine cone extract ; povidone-iodine ; HSV ; HIV ; loss of infectivity ; solubilization method ; diaphragmatic breathing ; abdominal breathing ; breathing exercise ; systematic review ; randomized controlled trial ; respiratory function ; auricular acupuncture ; preoperative anxiety ; protocol ; randomized controlled trials ; meta-analysis ; boiogito ; knee osteoarthritis ; rat ; Yokukansan ; fentanyl ; transient receptor potential ankyrin 1 (TRPA1) channel ; phosphorylated extracellular signal-regulated kinase (pERK) ; whole-cell patch-clamp recording ; herbal medicine ; calcium metabolism ; bone metabolism ; protease ; osteoclast ; macrophage ; RANKL ; LPS ; TLR4 ; TREM2 ; bic Book Industry Communication::M Medicine
    Language: English
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  • 3
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    Radiation Response Biomarkers for Individualised Cancer Treatments (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-03-30
    Description: Personalised medicine is the next step in healthcare, especially when applied to genetically diverse diseases such as cancers. Naturally, a host of methods need to evolve alongside this, in order to allow the practice and implementation of individual treatment regimens. One of the major tasks for the development of personalised treatment of cancer is the identification and validation of a comprehensive, robust, and reliable panel of biomarkers that guide the clinicians to provide the best treatment to patients. This is indeed important with regards to radiotherapy; not only do biomarkers allow for the assessment of treatability, tumour response, and the radiosensitivity of healthy tissue of the treated patient. Furthermore, biomarkers should allow for the evaluation of the risks of developing adverse late effects as a result of radiotherapy such as second cancers and non-cancer effects, for example cardiovascular injury and cataract formation. Knowledge of all of these factors would allow for the development of a tailored radiation therapy regime. This Special Issue of the Journal of Personalised Medicine covers the topic of Radiation Response Biomarkers in the context of individualised cancer treatments, and offers an insight into some of the further evolution of radiation response biomarkers, their usefulness in guiding clinicians, and their application in radiation therapy.
    Keywords: carbon-ion radiotherapy ; head-and-neck tumors ; squamous cell carcinoma ; radiosensitivity ; relative biological effectiveness ; lung cancer ; radiotherapy ; radiotherapy monitoring ; radiation-induced lung injury ; RILI ; pneumonitis ; radiation-induced lung fibrosis ; RILF ; circulating biomarkers ; microRNA ; micronuclei ; uterine cervical cancer ; cGAS ; STING ; abscopal effect ; immunotherapy ; PBMCS ; micronucleus assay ; biological dosimetry ; human blood ; genotoxicity tests ; ionizing radiation ; biomarkers ; dicentric assay ; gamma H2AX foci assay ; health surveillance analyses ; clonogenic assays ; methods ; plating ; cancer ; radiation ; head and neck cancer ; exosomes ; serum ; metabolomics ; GC/MS ; biodosimetry ; chromosome aberrations ; normal tissue toxicity ; predictive tests ; normal tissue ; biomarker ; protein ; immune infiltrate ; stroma ; tumour microenvironment ; proteomics ; telomeres ; chromosomal instability ; inversions ; prostate cancer ; IMRT ; machine learning ; individual radiosensitivity ; late effects ; personalized medicine ; liquid biopsy ; circulating tumour cells ; extracellular vesicles ; microRNAs ; immune system ; inflammation ; n/a
    Language: English
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  • 4
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    Cellular Senescence in Health, Disease and Aging: Blessing or Curse? (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-03-28
    Description: Dear Colleagues, When Hayflick and Moorhead coined the term “cellular senescence” (CS) almost 60 years ago, this phenomenon was understood as a mechanism, usually induced by activation of the DNA-repair machinery, to prevent uncontrolled proliferation. Meanwhile, additional beneficial roles for CS have been identified, such as embryonic development and wound healing. The senescence associated secretory phenotype (SASP) activated in most senescent cells (SC) signals to the immune system “come here and remove me”. In organisms with young and functional immune systems, occurring SC are usually detected and removed. If SC remain in the tissue expressing the SASP, this will cause not just a damaging local inflammation but can also induce remodeling and regeneration of the surrounding tissue as well as spreading of senescence. Old organisms show reduced regenerative potential and immune function which leads to accumulation of SC. Accordingly, accumulation of SC was observed in tissues of aged individuals, but importantly also in the context of age-related disorders, neurodegenerative, or cardiovascular diseases and others. Because of its detrimental effect of the surrounding tissue, accumulation of SC is not just a consequence, but can rather been understood as a major driver of aging. In line with this, recent studies described that removal of SC showed beneficial effects on healthspan and lifespan. This exciting research led to the discovery of “senolytics”, drugs which can kill SC. Given the heterogeneity of cell types that show senescence-like phenotypes, including heart muscle and post-mitotic neuronal cells, further research is required to unravel the molecular background that renders a cell type vulnerable to senesce. Additionally, it will be important to understand how senescence is cell type-specifically induced and which molecules serve as drug targets to prevent senescence and its spreading, or actively kill SC. This special issue will shed light on the molecular pathways of CS and inflammaging and on possible strategies to interfere with these processes. Dr. Markus Riessland Guest Editor
    Keywords: γH2AX ; Alzheimer’s disease ; DNA damage ; mild cognitive impairment ; senescence ; secreted protein acidic and rich in cysteine ; regeneration ; homeostasis ; cellular senescence ; biology of aging ; neurodegeneration ; brain ; geroscience ; senolytics ; tauopathy ; cancer ; stress response ; post-mitotic ; neuronal senescence ; amyotrophic lateral sclerosis ; senescence-associated secretory phenotype (SASP) ; cell-cycle ; melanoma ; pancreatic adenocarcinoma ; tumor infiltration ; chemotherapy resistance ; prostate ; inflammation ; AIM2 inflammasome ; POP3 ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 5
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    New Perspectives in Health (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
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    Publication Date: 2022-10-25
    Description: Gut microbiota are an area recently targeted by modern biomedical research. In fact, during the last five years, there has been increasing evidence related to the role of gut microbiota as remarkable symbiotic partners critical for the maintenance of good health. Several factors cause alterations in gut microbiota which are, indeed, accompanied by alterations in the quality of health. Accordingly, gut microbiota dysbiosis has been related to increased susceptibilities to intestinal, cardiovascular, and nervous pathologies. In this manual, you will find the latest studies carried out in the field of microbiota. Overall, the contributions published in this Special Issue further strengthen the essential function of gut microbiota in health and in various diseases.
    Keywords: gut microbiota ; anti-TNFα ; Crohn’s disease ; Faecalibacterium prausnitzii ; Escherichia coli and Clostridium coccoides group ; obesity ; percutaneous electrical stimulation ; dermatome T6 ; microbiota ; probiotics ; resistance ; survivability ; gastrointestinal passage ; gut ; nicotinic acetylcholine receptors ; α7 and α9 nicotinic receptor subtypes ; cholinergic anti-inflammatory pathway ; gut-brain axis ; gut microbiome ; dysbiosis ; inflammatory bowel disease ; COVID-19 ; dioxide titanium ; TiO2 ; E171 ; CI 77891 ; food additive ; gut barrier ; immunity ; toxicity ; diet ; memory ; attention ; gut–brain axis ; gastrointestinal microbiome ; fibromyalgia ; drug therapy ; neoplasms ; radiotherapy ; systematic review ; autoimmunity ; multiple sclerosis ; inflammation ; cytokines ; intestinal permeability ; disease modifying drugs ; food-derived opioids ; casomorphin ; gliadorphin ; opioid receptors ; A1 beta-casein ; beta-casomorphin-7 ; gut-to-brain ; microbiome ; DPP4 ; fecal microbiota ; isoflavones ; equol ; pyrosequencing ; menopause ; fatty acids ; stool ; stool collection ; Cambodia ; sample collection ; rural health ; collection kit ; allergy ; osteoporosis ; bone metabolism ; food allergy ; skeletal health ; osteoimmunology ; n/a ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine
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  • 6
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    Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
    Details
    Publication Date: 2024-04-11
    Description: Dear colleagues, This Special Issue, “Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches”, focuses on the pathophysiology of endothelial dysfunction, new biomarkers for endothelial dysfunction related to cardiovascular disorders or tumors, and novel therapeutic approaches for endothelial dysfunctions. Vascular endothelium is an active tissue and plays a crucial role in the maintenance of vascular homeostasis. Chronic exposure to risk factors, such as hypertension, high cholesterolemia, or oxidative stress, induces endothelial dysfunctions and results in a loss of endothelial integrity, smooth muscle cell proliferation, and macrophage recruitment. The pathophysiology of endothelial dysfunction (ED) is complex and multi-factorial factors are involved, such as oxidative stress or chronic inflammation. The primary prevention of cardiovascular risk factors and endothelial dysfunctions, as well as the early detection of or molecular imaging techniques for endothelial dysfunction, helps to prevent the development of cardiovascular disorders. Novel therapeutic approaches or drug delivery systems for endothelial dysfunctions have had promising beneficial effects in preclinical or clinical levels by affecting the progression of atherosclerotic changes, tumor angiogenesis, and host–immune reactions near tumor environments.
    Keywords: endothelial cells ; oxidative stress ; inflammageing ; endothelial dysfunction ; aldehyde dehydrogenase-2 ; cardiovascular disease ; neurovascular disease ; vascular inflammation ; APE1/Ref-1 ; cardiovascular diseases ; subcellular localization ; serological biomarkers ; atherosclerosis ; aerobic exercise ; PCSK9 ; LOX-1 ; insulin resistance ; macrophage polarity ; serum γ-glutamyltransferase ; essential hypertension ; cardiovascular risk factors ; angiogenesis ; nargenicin A1 ; compound 9 ; VEGF ; VEGFR2 ; HIF-1α ; electronegative low-density lipoprotein ; LDL(–) ; L5 LDL ; oxidized LDL ; oxLDL ; ADMA ; arginine ; arginine paradox ; BH4 ; blood pressure ; COVID-19 ; dietary supplements ; endothelium ; eNOS uncoupling ; heart failure ; hypertension ; L-arginine ; myocardial infarction ; NADPH ; nitric oxide ; peripheral artery disease ; ApoE knockout mouse ; atorvastatin ; VCAM-1 ; galectin-3 ; neutrophil/lymphocyte ratio ; electronegative LDL ; LDL(−) ; lectin-like oxLDL receptor-1 ; dyslipidemia ; chronic venous insufficiency ; prolyl oligopeptidase (POP) ; inflammation ; endothelial disfunction ; lung disease ; endothelial to mesenchymal transition ; pulmonary hypertension ; pulmonary fibrosis ; metformin ; diabetes ; CV risk ; hyperglycemia ; glycated lipoproteins ; glycated LDL ; glycated HDL ; endothelial cell dysfunction ; molecular mechanisms ; epigenetic factors ; therapeutic approaches ; vasoactive factors ; EndoMT ; TGF-β ; epigenetics ; endothelial cell ; glycolysis ; metabolism ; pathological angiogenesis ; tumor microenvironment ; MRI (magnetic resonance imaging) ; high-fat diets ; plaque burden ; low-level laser therapy ; phototherapy ; vascular disease ; healing ; ischemia ; vascular calcification ; chronic kidney disease ; CKD ; uremic toxins ; hyperphosphatemia ; vascular smooth muscle cells ; VSMCs ; macrophages ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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  • 7
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    Cutting-Edge Topics in Dry Eye Disease (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
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    Publication Date: 2022-02-01
    Description: This text presents cutting-edge topics on and the diagnostic and therapeutic approaches for tear film abnormities, including dry eye disease and Meibomian gland dysfunction. A new management algorithm for Meibomian gland dysfunction, therapeutic eye drops and intense pulsed lasers for dry eye disease, and topical and systemic agents for neuropathic ocular pain are proposed in this issue.
    Keywords: cross-sectional study ; dry eye disease ; systemic comorbidity ; graves’ ophthalmopathy ; inflammation ; meibomian glands ; morphological changes ; meibomian gland dysfunction ; ocular surface disease ; dry eye symptoms ; questionnaire ; Bangladesh ; global health ; epidemiology ; aqueous-deficient dry eye ; meibomian gland ; intense pulsed light ; severe keratitis ; hyaluronan ; hylan A ; multicenter ; randomized trial ; gabapentin ; dry eye ; neuropathic pain ; diabetes ; neuropathic keratopathy ; neuropathy ; nerve growth ; neurotrophic ; Houttuynia ; ultrasonic atomization ; meibography ; meiboscore ; TRPM8 agonist ; cryosim-3 ; fatty acids ; vitamin D ; brief-type self-administered diet history questionnaire ; Japanese ; bic Book Industry Communication::M Medicine
    Language: English
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  • 8
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    Recent Clinical Research on Glaucoma (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
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    Publication Date: 2022-05-06
    Description: In the past few years, knowledge about glaucoma diagnosis and follow up has evolved dramatically through advances in intraocular pressure (IOP) measurement, corneal biomechanics, structural and functional assessment of the ocular surface, anterior chamber, retina, optic nerve and intracranial visual pathways, as well as the advent of artificial intelligence. In addition, the development of new modalities of IOP-lowering and non-IOP-lowering drugs, alternative deliveries, refined laser technologies, and minimally invasive glaucoma surgery (MIGS) techniques with different implants have widened the therapeutic possibilities for treating this disease. Finally, current insights into risk factors and quality of life in relation to glaucomatous impairment are emerging. The purpose of this Special Issue is to present the latest exciting clinical developments that are taking place in the field of glaucoma.
    Keywords: ripasudil ; suture trabeculotomy ab interno ; Schlemm’s canal incision ; aqueous outflow ; open-angle glaucoma ; glaucoma ; inflammation ; oxidative stress ; phenotype ; polymorphism ; susceptibility ; intraocular pressure ; ocular inflammation ; cornea biomechanics ; Corvis® ST ; subclinical keratoconus ; ocular hypertension ; tears ; miRNAs ; next generation sequencing ; biomarkers ; genes ; signaling pathways ; apoptosis ; neurodegeneration ; glaucoma suspect ; lamina cribrosa ; optical coherence tomography angiography ; peripapillary vessel density ; OCTA ; vessel density ; disc ; peripapillary ; NTG ; BRVO ; corneal hysteresis ; corneal biomechanics ; ocular biomarkers ; deep learning ; perimetry ; optic nerve ; obesity ; risk factor ; young adults ; multifocal visual evoked potentials ; mfVEP ; physical exercise ; sport ; acrobatic gymnastics ; baseline intraocular pressure ; central corneal thickness ; ocular health ; tumbling skills ; hand balance ; cytokines ; BDNF ; VEGF ; fractalkine ; microglia ; saffron ; crocin ; retinal glial cells ; microperimetry ; OCT ; macula ; structure ; function ; correlation ; retina ; inner ; outer ; macular segmentation ; optical coherence tomography-angiography ; vascular density ; blood flow ; biomarker ; myopia ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 9
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    Genetics of Alzheimer’s Disease (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
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    Publication Date: 2022-02-24
    Description: This special issue on the genetics of Alzheimer's disease was edited by Drs. Laura Ibanez and Justin Miller in 2021. It contains 10 original articles and reviews that help readers understand specific genetic contributions to Alzheimer's disease and how genetics will play a role in future Alzheimer's disease research.
    Keywords: Alzheimer disease ; expression quantitative trait loci (eQTL) ; rare variants ; set-based eQTL ; SKAT-O ; pathways ; immune system ; inflammation ; ROSMAP ; ADNI ; complement ; complement receptor 1 ; clusterin ; late-onset Alzheimer’s disease ; genetics ; neuroinflammation ; Alzheimer’s disease ; cytokines and growth factors ; genome-wide association study (GWAS) ; Polygenic Risk Score (PRS)-based analysis ; TOMM40 gene ; RNA transcription ; pseudogene ; mitochondrial dysfunction ; ITIM ; ITAM ; SIGLEC14 ; SIGLEC5 ; copy number variation ; CNV ; GWAS ; long non-coding RNA ; biomarkers ; peripheral system ; amyloid β ; tau ; APOE ; TREM2 ; OMICS ; therapeutics ; pairwise feature correlation ; feature reduction ; machine learning ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 10
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    Oxidative Stress and Inflammation (2022)
    MDPI - Multidisciplinary Digital Publishing Institute
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    Publication Date: 2022-12-06
    Description: In the biochemical reactions that take place within all living beings, species called free radicals are generated. Denham Harman, in his study on the origin and evolution of life (Harman, 2001), proposes that these species are amongst the causes of the origin of life on our planet. Oxygen is a molecule that provides the primary source of energy in aerobic organisms and therefore is key to the development and evolution of life. On the one hand, it gives rise to life; on the other, due to its ability to form different free radicals, it is capable of damaging essential structures for development. To combat these radicals, our biological systems have developed antioxidant defenses. However, when the balance between free radicals and antioxidant defenses is broken in favor of the former, a phenomenon called oxidative stress occurs, which ends up damaging molecules such as DNA, proteins, carbohydrates, and lipids (Sies, 1983) (Halliwell and Gutteridge, 1985). This phenomenon is implicated both in the development of diseases and in their progression. In addition, inflammation phenomena are also involved in most pathologies, which, although they are essential for tissue repair and immunity, turn against our bodies when they become excessively active. For these reasons, in this special edition we showcase an extensive knowledge of the effects of oxidative stress and inflammation both in diseases such as aging, or for its role in health.
    Keywords: diospyrin ; lipopolysaccharide ; anti-inflammation ; macrophages ; nitric oxide ; cytokine ; calcium ; CHOP ; Fas ; p38 MAPK ; Astragalus mongholicus Bunge ; danazol ; telomere ; telomerase ; aging ; diabetic kidney disease ; oxidative stress ; redox imbalance ; hyperimmunized milk ; exercise ; inflammation ; intestinal permeability ; acute respiratory distress syndrome ; antiplatelet ; aspirin ; therapy ; gender ; membrane erythrocyte ; hydroperoxides ; biomarker ; DPPP ; DPH ; TMA ; cardiovascular disease ; data analysis ; precision–recall ; Mediterranean diet ; Oriental diet ; nutrition ; polyphenols ; microbiota ; health ; n-3 PUFAs ; endogenous antioxidants ; anti-inflammatory response ; cardiovascular diseases ; dry eye syndrome ; corneal damage ; tear lipidome ; 5-lipoxigenase ; leukotriene B4 ; prostaglandins ; dimethyl sulfoxide ; zileuton ; air pollution ; soot ; particulate matter ; lung inflammation ; functional groups ; microglia ; porcine liver decomposition product ; lysophospholipids ; mild cognitive impairment ; dementia ; neuroinflammation ; cytokines ; oxygen reactive species ; caloric restriction ; oxidative balance ; adiponectin ; plasma ; white adipose tissue ; experimental model ; anti-inflammatory diets ; inflammatory response ; chronic inflammation ; low grade chronic inflammation ; inflammatory models ; cyclophosphamide ; doxorubicin ; docetaxel ; paclitaxel ; n/a ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine
    Language: English
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