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  • PNAS Profiles  (32)
  • National Academy of Sciences  (32)
  • American Meteorological Society
  • Blackwell Publishing Ltd
  • Copernicus
  • Hindawi
  • Institute of Electrical and Electronics Engineers
  • Molecular Diversity Preservation International
  • Public Library of Science
  • Springer Nature
  • Springer Science + Business Media
  • 2020-2022
  • 2010-2014  (32)
  • 1985-1989
  • 1970-1974
  • 1960-1964
  • 1950-1954
  • 1940-1944
  • 2012  (32)
Collection
Publisher
  • National Academy of Sciences  (32)
  • American Meteorological Society
  • Blackwell Publishing Ltd
  • Copernicus
  • Hindawi
  • +
Years
  • 2020-2022
  • 2010-2014  (32)
  • 1985-1989
  • 1970-1974
  • 1960-1964
  • +
Year
  • 1
    Publication Date: 2012-02-08
    Description: From the moment 17-year-old David Karl first glimpsed the ocean from the summit of Cadillac Mountain on Maine's Mount Desert Island, he was captivated by the blue waters surrounding the fog-veiled islands. Since then, he has contributed to some of the world's most pivotal discoveries in oceanography. Karl, who was elected to the National Academy of Sciences (NAS) in 2006 and is now a professor of oceanography at the School of Ocean and Earth Science and Technology at the University of Hawaii, has witnessed iconic moments like the discovery of hydrothermal vents at the Galapagos Rift. His work on 23...
    Keywords: PNAS Profiles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 2
    Publication Date: 2012-10-17
    Description: A busy factory with intricate connections to the bloodstream, bone marrow is one of the most extensive—and active—tissues in the body, churning out cellular precursors of the bloodstream, immune system, fat, and bone. For all its activity, the response of the bone marrow to conditions like obesity is often ignored....
    Keywords: PNAS Profiles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
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  • 3
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    National Academy of Sciences
    Publication Date: 2012-04-11
    Description: In the past two decades, microarrays, so-called omics technologies, and improved methods for nucleic acid sequencing have created a vast amount of biological data for researchers to sort through. Pioneering fields of science have sprung up in response to this challenge, eager to create helpful tools by leveraging the expertise of scientists in fields as diverse as mathematics and physics. Condensed matter physicist Eric Siggia, a recently elected member of the National Academies of Sciences, has been at the forefront of this movement.pnas;109/15/5551/UNFIG01F1unfig01Eric D. Siggia.In 1997, Siggia was one of only three physicists at The Rockefeller University in New York...
    Keywords: PNAS Profiles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
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  • 4
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    National Academy of Sciences
    Publication Date: 2012-08-29
    Description: Meiosis sets the stage for sexual reproduction through a trifold and tightly choreographed dance: Chromosomes from the mother and father form pairs, exchange genetic material, and then separate from their partners. Geneticist R. Scott Hawley, who has studied these three steps for the better part of his career, has dubbed...
    Keywords: PNAS Profiles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
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  • 5
    Publication Date: 2012-09-05
    Description: Nancy Craig studies how DNA moves from place to place: a deceptively simple quest that has revealed how transposons, or so-called “DNA cut-and-paste elements,” snip themselves from one location on the chromosome and resettle in another. Craig, a professor of molecular biology and genetics at Johns Hopkins University School of...
    Keywords: PNAS Profiles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
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  • 6
    Publication Date: 2012-08-29
    Description: A man does what he must—in spite of personal consequences, in spite of obstacles and dangers and pressures—and that is the basis of all human morality.—Sir Winston Churchill, British politician (1874–1965)F. Sherwood (Sherry) Rowland was best known for his ground-breaking work on the impact of chlorofluorocarbons (CFCs) on stratospheric ozone....
    Keywords: PNAS Profiles
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    Electronic ISSN: 1091-6490
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  • 7
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    National Academy of Sciences
    Publication Date: 2012-07-25
    Description: George Church wants to rewrite the genetic code. A virtual manual of protein synthesis, the code reflects how organisms interpret strings of letters in the genome into strings of amino acids in proteins. Exploiting the code's redundancy, Church, a recently elected member of the National Academy of Sciences and a professor of genetics at Harvard Medical School, hopes to alter the genetic code of bacteria to enable the production of proteins with unnatural amino acids, a step toward radical genome tailoring that could someday lead to a range of applications in medicine and microbiology. To that end, Church's graduate student,...
    Keywords: PNAS Profiles
    Print ISSN: 0027-8424
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  • 8
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    National Academy of Sciences
    Publication Date: 2012-06-13
    Description: More than a decade ago, Shinya Yamanaka gazed through a microscope at human embryos growing in a laboratory dish at a fertility clinic in Osaka, Japan. The pulsating blobs struck a primitive chord in the young researcher. “Watching the embryos, I felt that if there was a way to find cures for human diseases without destroying them, then that's what I should pursue,” recalls Yamanaka, a stem cell biologist at Japan's Kyoto University and a newly elected foreign associate of the National Academy of Sciences. That close encounter with a kernel of human life led to a scientific exploration with...
    Keywords: PNAS Profiles
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    Electronic ISSN: 1091-6490
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  • 9
    Publication Date: 2012-07-18
    Description: Fluctuations in biodiversity are not just collateral damages in the face of global environmental change, according to Sandra Díaz, a professor of community and ecosystems ecology at Córdoba National University in Argentina and a senior principal researcher of the Argentine National Research Council. Díaz explores how the chemical and physical traits of plants—such as size, texture, and nutrient content of leaves, wood density, palatability to herbivores, and canopy architecture—influence a plant’s response to the environment and play an active role in the planet’s constant evolution in response to environmental change.pnas;109/29/11469/UNFIG01F1unfig01Sandra M. Díaz.Díaz has uncovered the important variables driving ecosystem functions...
    Keywords: PNAS Profiles
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    Electronic ISSN: 1091-6490
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  • 10
    Publication Date: 2012-07-11
    Description: Protein kinases are the workhorses of the cell, orchestrating complex cellular activities by carrying out a relatively simple chemical modification: the transfer of a phosphate molecule from ATP to a protein or lipid substrate via a process called phosphorylation. Kinases are crucial to the function of all living organisms, and deregulated kinase activity lies at the heart of humanity’s most pernicious diseases, including cancer, cardiovascular disease, neurodegeneration, and diabetes. But deciphering the role of each of the more than 500 kinases encoded in the human genome has proven remarkably challenging.pnas;109/28/11057/UNFIG01F1unfig01Kevan M. Shokat.A kinase’s function—and its role in disease—can only become...
    Keywords: PNAS Profiles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
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