ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

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Core Concept: Human artificial chromosomes offer insights, therapeutic possibilities, and challenges [Cell Biology] (2017)

Amber Dance

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2017-09-13

Beschreibung: Francesco Saverio Tedesco works with a big gene. In fact, the human dystrophin gene, with its whopping 2.4 million nucleotides, is one of the largest found so far in nature. A clinician-scientist at University College London, Tedesco hopes to use gene therapy to replace a faulty version of dystrophin in...

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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Chimeras keep courting controversy [Medical Sciences] (2016)

Dolgin, E.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2016-10-26

Beschreibung: Last autumn, the US National Institutes of Health announced it would not fund any research that entails introducing human pluripotent stem cells into early embryos of another species, including laboratory stalwarts, such as mice, or larger animals like pigs. The agency said it wanted a chance to conduct a formal...

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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Core Concept: How Bose-Einstein condensates keep revealing weird physics [Physics] (2017)

Stephen Ornes

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2017-06-07

Beschreibung: A Bose-Einstein condensate (BEC), the first of which was shown experimentally 22 years ago, isn’t your garden variety state of matter. It formed at a fraction above absolute zero and only in atoms that act like bosons, one of two types of fundamental particles. Bosons don’t follow the Pauli exclusion...

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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Core Concepts: How diversity-generating retroelements promote mutation and adaptation in myriad microbes [Cell Biology] (2017)

Carrie Arnold

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2017-10-04

Beschreibung: Adaptation, a cornerstone of evolutionary change, is rarely straightforward. Acquiring a random mutation that promotes survival can take generations. Prokaryotes such as bacteria and Archaea, along with the viruses they harbor, have compact genomes, leaving them with a limited repertoire of DNA to respond to environmental change. Fig. 1. After...

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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Core Concept: Tissue resident memory cells emerging as key player in health and disease [Immunology and Inflammation] (2017)

Bob Roehr

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2017-11-15

Beschreibung: Much of our understanding of the immune system has come from studying immune cells drawn from blood. Such samples are minimally invasive and relatively easy to collect, but they provide an incomplete and often misleading picture. Put simply, the biology of the immune system in blood doesn’t match the biology...

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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Core Concept: Circumventing the blood-brain barrier [Neuroscience] (2017)

Helen H. Shen

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2017-10-25

Beschreibung: If the brain is the body’s central processing unit, then the blood–brain barrier is its firewall. A specialized network of cells that lines the brain’s vascular system, the blood–brain barrier selectively ushers in nutrients and other essential biomolecules while denying entry to most everything else. But the same system that...

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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Core Concept: Role player or cellular rubbish? Biologists debate the function of neutrophil extracellular traps [Immunology and Inflammation] (2017)

Jyoti Madhusoodanan

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2017-12-20

Beschreibung: Thirteen years ago, microscopy researcher Volker Brinkmann spotted a bizarre behavior while peering at immune cells called neutrophils to study how they killed bacteria. Like the quick flick of a frog’s tongue, neutrophils shot out strands of nuclear DNA to trap passing microbes. In this scanning electron microscope image, NETs...

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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Core Concept: Stabilizing turbulence in fusion stellarators [Physics] (2017)

Adam Mann

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2017-02-08

Beschreibung: In the earliest days of the Cold War, physicists on both sides of the Iron Curtain raced to harness energy from nuclear fusion, which could, in principle, provide nearly limitless electricity. Innovative devices with names like pinch machines, levitrons, and superstators flourished, and for most of the 1950s it was...

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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Core Concept: Prebiotics gain prominence but remain poorly defined [Microbiology] (2016)

Alla Katsnelson

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2016-12-14

Beschreibung: With the gut microbiome increasingly recognized as a major player in shaping human biology, probiotic treatments—introducing a few billion purportedly beneficial micro-organisms into human gut communities composed of trillions of microbes—are under intense investigation. Study designs and results have been a mixed bag, and the impact of probiotics remains unclear....

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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Core Concept: Cryopreservation aims to engineer novel ways to freeze, store, and thaw organs [Medical Sciences] (2017)

Megan Scudellari

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences

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Publikationsdatum: 2017-12-13

Beschreibung: Five years ago, even top cryobiologists doubted that a human organ would ever be successfully frozen and thawed. It felt like “a long, long scientific step” from the freezing of cells or millimeter-thick tissues to the freezing of whole organs, says Janet Elliott, Canada Research Chair in Thermodynamics at the...

Schlagwort(e): Core Concepts, Front Matter

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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