ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

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Digitale Medien

News In Brief (2006)

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1048-1049

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] 200% ethanol boost from Oz sugar University of Queensland (UQ), Australia, molecular geneticist Robert Birch got more than he bargained for when he introduced a bacterial gene into sugarcane to convert sucrose into its high-value isomer, isomaltulose. In fact, the gene encoding sucrose isomerase, ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt0706-1048

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2

Digitale Medien

Profile of a bacterial tumor killer (2006)

Forbes, Neil S

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1484-1485

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] Common bacteria, engineered to safely seek out and kill tumors, may well be the next generation of cancer therapeutics. In this issue, Bettegowda et al. report the genome sequence of one such bacterium, Clostridium novyi-NT, which has been engineered to be non-toxic by deleting the major systemic ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt1206-1484

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3

Digitale Medien

Anti-infective antibodies: finding the path forward (2006)

Baker, Monya

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1491-1493

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] This June, Basel-based Novartis Pharmaceuticals made a first reconnoiter into antimicrobial antibodies in its quest to find new weapons to fight infections. It paid $569 million to acquire NeuTec Pharmaceuticals of Manchester, UK, and its two late-stage products, both antibody fragments ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt1206-1491

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4

Digitale Medien

Prospects for plant-derived antibacterials (2006)

Lewis, Kim ; Ausubel, Frederick M

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1504-1507

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] The scarcity of disease in wild plants indicates that the success of plant defense mechanisms in combating pathogen infection rivals that of mammalian immune systems. Although there are some interesting parallels between plant and animal defense strategies—for instance, both groups sacrifice ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt1206-1504

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5

Digitale Medien

Moving goalposts—regulatory oversight of antibacterial drugs (2006)

Brenner, Randall ; Ellis-Grosse, Evelyn J ; Echols, Roger

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1515-1519

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] The US Food and Drug Administration (FDA) has recently rejected new antibiotics for common infections citing the requirement that the drugs intended to treat non-serious infections prove superior to placebo rather than active controls. With the introduction of more stringent statistical criteria, ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt1206-1515

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6

Digitale Medien

The business of developing antibacterials (2006)

Fox, Jeffrey L

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1521-1528

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] For developers of antibacterial products, this century began very much on the wrong foot. The number of pharmaceutical companies chasing antibiotics continued to drop, few genuinely new antibiotics reached the clinic and investors remained lukewarm toward startups in this sector. But, despite ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt1206-1521

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7

Digitale Medien

What is a support vector machine? (2006)

Noble, William S

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1565-1567

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] A support vector machine (SVM) is a computer algorithm that learns by example to assign labels to objects. For instance, an SVM can learn to recognize fraudulent credit card activity by examining hundreds or thousands of fraudulent and nonfraudulent credit card activity reports. Alternatively, an ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt1206-1565

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8

Digitale Medien

The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT (2006)

Bettegowda, Chetan ; Huang, Xin ; Lin, Jimmy ; [weitere]

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1573-1580

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] Bacteriolytic anti-cancer therapies employ attenuated bacterial strains that selectively proliferate within tumors. Clostridium novyi-NT spores represent one of the most promising of these agents, as they generate potent anti-tumor effects in experimental animals. We have determined the 2.55-Mb ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt1256

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9

Digitale Medien

Blue fluorescent proteins with enhanced brightness and photostability from a structurally targeted library (2006)

Mena, Marco A ; Treynor, Thomas P ; Mayo, Stephen L ; [weitere]

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1569-1571

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] The utility of blue fluorescent protein (BFP) has been limited by its low quantum yield and rapid photobleaching. A library targeting residues neighboring the chromophore yielded a variant with enhanced quantum yield (0.55 versus 0.34), reduced pH sensitivity and a 40-fold increase in ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt1264

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10

Digitale Medien

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies (2006)

Sahl, Hans-Georg ; Hancock, Robert E W

[s.l.] : Nature Publishing Group

Nature biotechnology 24 (2006), S. 1551-1557

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] Short cationic amphiphilic peptides with antimicrobial and/or immunomodulatory activities are present in virtually every life form, as an important component of (innate) immune defenses. These host-defense peptides provide a template for two separate classes of antimicrobial drugs. Direct-acting ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt1267

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