ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

1

Electronic Resource

Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay (2005)

Cleary, Michael D ; Meiering, Christopher D ; Jan, Eric ; [et al.]

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 232-237

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] Standard microarrays measure mRNA abundance, not mRNA synthesis, and therefore cannot identify the mechanisms that regulate gene expression. We have developed a method to overcome this limitation by using the salvage enzyme uracil phosphoribosyltransferase (UPRT) from the protozoan Toxoplasma ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt1061

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2

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Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans (2005)

Prust, Christina ; Hoffmeister, Marc ; Liesegang, Heiko ; [et al.]

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 195-200

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] Gluconobacter oxydans is unsurpassed by other organisms in its ability to incompletely oxidize a great variety of carbohydrates, alcohols and related compounds. Furthermore, the organism is used for several biotechnological processes, such as vitamin C production. To further our understanding of ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt1062

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3

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Detection of parallel functional modules by comparative analysis of genome sequences (2005)

Li, Huiying ; Pellegrini, Matteo ; Eisenberg, David

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 253-260

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] Parallel functional modules are separate sets of proteins in an organism that catalyze the same or similar biochemical reactions but act on different substrates or use different cofactors. They originate by gene duplication during evolution. Parallel functional modules provide versatility and ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt1065

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4

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Minimum information requested in the annotation of biochemical models (MIRIAM) (2005)

Finney, Andrew ; Hucka, Michael ; Bhalla, Upinder S ; [et al.]

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 1509-1515

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] Most of the published quantitative models in biology are lost for the community because they are either not made available or they are insufficiently characterized to allow them to be reused. The lack of a standard description format, lack of stringent reviewing and authors' carelessness are the ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt1156

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5

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The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K (2005)

Chaillou, Stéphane ; Champomier-Vergès, Marie-Christine ; Cornet, Monique ; [et al.]

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 1527-1533

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] Lactobacillus sakei is a psychrotrophic lactic acid bacterium found naturally on fresh meat and fish. This microorganism is widely used in the manufacture of fermented meats and has biotechnological potential in biopreservation and food safety. We have explored the 1,884,661-base-pair (bp) circular ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt1160

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6

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Efficient differentiation of human embryonic stem cells to definitive endoderm (2005)

D'Amour, Kevin A ; Agulnick, Alan D ; Eliazer, Susan ; [et al.]

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 1534-1541

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] The potential of human embryonic stem (hES) cells to differentiate into cell types of a variety of organs has generated much excitement over the possible use of hES cells in therapeutic applications. Of great interest are organs derived from definitive endoderm, such as the pancreas. We have ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt1163

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7

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Combined static and dynamic analysis for determining the quality of time-series expression profiles (2005)

Simon, Itamar ; Siegfried, Zahava ; Ernst, Jason ; [et al.]

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 1503-1508

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] Expression profiling of time-series experiments is widely used to study biological systems. However, determining the quality of the resulting profiles remains a fundamental problem. Because of inadequate sampling rates, the effect of arrest-and-release methods and loss of synchronization, the ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt1164

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8

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The problem with potency (2005)

Scott, Christopher Thomas

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 1037-1039

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] As the $30 billion monoclonal antibody (mAb) market moves from murine-based to chimeric and fully human products, it grows at a compounded clip of nearly 20% per year (see ). This spectacular growth—Synagis (pavilivizumb; MedImmune, Gaithersburg, Maryland), Herceptin (trastuzumab; ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt0905-1037

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9

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Problems with metagenomic screening (2005)

de Lorenzo, Victor

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 1045-1045

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] To the editor: The paper by Kazuya Watanabe and colleagues published in the January issue (Nat. Biotechnol. 23, 88–93, 2005) is framed both in the paper itself and in the accompanying News & Views by Jo Handelsman (Nat. Biotechnol. 23, 38–39, 2005) as an astute, general genetic ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt0905-1045a

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10

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Reply to "Problems with metagenomic screening" (2005)

Watanabe, Kazuya ; Uchiyama, Taku

[s.l.] : Nature Publishing Group

Nature biotechnology 23 (2005), S. 1045-1046

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ISSN: 1546-1696

Source: Nature Archives 1869 - 2009

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: [Auszug] Watanabe and colleagues respond: de Lorenzo outlines some possible limitations of the substrate-induced gene expression screening (SIGEX) method. Although we discussed many of the points in his letter in our paper, it is worth reiterating them to emphasize the challenges faced in designing a ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nbt0905-1045b

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