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Digitale Medien

What's brewing in genetic testing (2002)

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 553-554

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] The US Department of Health and Human Services (HHS) recently disbanded at least two expert advisory committees, the National Human Research Protections Advisory Committee and the Secretary's Advisory Committee on Genetic Testing (SACGT). As reported on 17 September in the Washington Post, this ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1202-553

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2

Digitale Medien

HRPT2 , encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome (2002)

Robbins, C.M. ; Villablanca, A. ; Forsberg, L. ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 676-680

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] We report here the identification of a gene associated with the hyperparathyroidism–jaw tumor (HPT–JT) syndrome. A single locus associated with HPT–JT (HRPT2) was previously mapped to chromosomal region 1q25–q32. We refined this region to a critical interval of 12 cM by ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1048

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3

Digitale Medien

Cellular clockwork (2002)

Nitabach, Michael N. ; Blau, Justin

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 559-560

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] It is well established that rhythms of gene expression in pacemaker neurons regulate sleep–wake cycles in flies and mammals. But these molecular circadian clocks are not limited to neurons, and even cultured fibroblast and hepatoma cell lines keep circadian time with oscillations in gene ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1202-559

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4

Digitale Medien

Unfolding heterochromatin for replication (2002)

de la Serna, Ivana L. ; Imbalzano, Anthony N.

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 560-562

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Chromatin can be divided into euchromatin and heterochromatin. Euchromatin contains a large portion of actively transcribing genes and undergoes decondensation during interphase. Heterochromatin stains densely throughout all phases of the cell cycle, is frequently located at the periphery of the ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1202-560

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5

Digitale Medien

Deciphering tsetse's secret partner (2002)

Wren, Brendan W.

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 335-336

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Bacteria are the most populous organisms on the planet, probably followed by insects. Thus it is not surprising that bacteria and arthropods are often intimately linked, depending on each other for their coexistence. One striking example of this dependence is the bloodsucking tsetse fly (Dipteria: ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1102-335

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6

Digitale Medien

Pathways of neuronal migration (2002)

Reiner, Orly

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 341-342

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Aristaless-related proteins (including Arx) belong to the Pax family of homeobox transcription factors, several members of which are known to be involved in genetic diseases. On page 359 of this issue, Kunio Kitamura and colleagues use a gene-targeting approach to identify a pivotal role for the ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1102-341

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7

Digitale Medien

Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret (2002)

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 331-331

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Nature Genet. 32, 109–115 (2002). The article was missing a reference to Web Movie A, which should have appeared on the last line of page 110 together with the reference to Web Fig. ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1002-331b

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8

Digitale Medien

Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1 (2002)

Nakae, Jun ; Biggs, William H. ; Kitamura, Tadahiro ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 245-253

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Type 2 diabetes results from impaired action and secretion of insulin. It is not known whether the two defects share a common pathogenesis. We show that haploinsufficiency of the Foxo1 gene, encoding a forkhead transcription factor (forkhead box transcription factor O1), restores insulin ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng890

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9

Digitale Medien

Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing (2002)

Kimura, Akatsuki ; Umehara, Takashi ; Horikoshi, Masami

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 370-377

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Genes located in chromosomal regions near telomeres are transcriptionally silent, whereas those located in regions away from telomeres are not. Here we show that there is a gradient of acetylation of histone H4 at lysine 16 (H4–Lys16) along a yeast chromosome; this gradient ranges from a ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng993

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10

Digitale Medien

Blinded by the light (2002)

Jacobson, Samuel G. ; McInnes, Roderick R.

[s.l.] : Nature Publishing Group

Nature genetics 32 (2002), S. 215-216

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] We all know that overexposure to light—for example, from directly watching a solar eclipse—can damage the retina. But in the mid 1960s, Noell and colleagues made the surprising observation that visible light “at intensities which are ordinarily encountered” may, at least in ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1002-215

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