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  • American Association for the Advancement of Science (AAAS)
  • Nature Publishing Group
  • 1995-1999  (1,668)
  • 1955-1959
  • 1999  (1,668)
  • 1
    Electronic Resource
    Electronic Resource
    Structural evidence for dimerization-regulated activation of an integral membrane phospholipase (1999)
    [s.l.] : Nature Publishing Group
    Nature 401 (1999), S. 717-721 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Dimerization is a biological regulatory mechanism employed by both soluble and membrane proteins. However, there are few structural data on the factors that govern dimerization of membrane proteins. Outer membrane phospholipase A (OMPLA) is an integral membrane enzyme which participates in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/44890
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  • 2
    Electronic Resource
    Electronic Resource
    The changing landscape of ischaemic brain injury mechanisms (1999)
    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A7-, (8 S.) 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] There is growing optimism among researchers in the field of brain ischaemia, as human stroke has at last become treatable and current research efforts delineate several new, potential therapies. Most strokes are caused by acute interruption of the brain arterial blood supply by a thrombus, leading ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/399a007
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  • 3
    Electronic Resource
    Electronic Resource
    Emerging insights into the genesis of epilepsy (1999)
    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A15-, (8 S.) 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Epilepsy, a brain disorder that is characterized by recurrent seizures, refers to a collection of disorders that affect 1–2% of the population worldwide. A seizure is a brief change in behaviour caused by the disordered, synchronous and rhythmic firing of populations of neurons in the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/399a015
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  • 4
    Electronic Resource
    Electronic Resource
    Translating cell biology into therapeutic advances in Alzheimer's disease (1999)
    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A23-, (9 S.) 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Studies of the molecular basis of Alzheimer's disease exemplify the increasingly blurred distinction between basic and applied biomedical research.The four genes so far implicated in familial Alzheimer's disease have each been shown to elevate brain levels of the self-aggregating amyloid-β ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/399a023
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  • 5
    Electronic Resource
    Electronic Resource
    Prospects for new restorative and neuroprotective treatments in Parkinson's disease (1999)
    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A32-, (8 S.) 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Parkinson's disease (PD) is one of the major neurodegenerative disorders of middle and old age, and was originally described by James Parkinson in 1817. It is characterized by a trio of cardinal symptoms—muscle rigidity, tremor and bradykinesia—but can also involve postural deficits and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/399a032
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  • 6
    Electronic Resource
    Electronic Resource
    Progress in determining the causes and treatment of multiple sclerosis (1999)
    [s.l.] : Nature Publishing Group
    Nature 399.1999, Supplementary, A40-, (8 S.) 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The cause of multiple sclerosis remains unknown after more than a century of study. Unconfirmed work has once more indicated that a viral infection may be important in the aetiology of the disease, and there is considerable evidence for an important genetic influence on disease susceptibility. The ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/399a040
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  • 7
    Electronic Resource
    Electronic Resource
    Stability offers unique opportunity for research (1999)
    [s.l.] : Nature Publishing Group
    Nature 398 (1999), S. 4-5 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] On 13 January this year, Brazil suffered a shock which, if you listen to some commentators abroad, shook it to its very core. In São Paulo the following week, however, the locals were unfazed. By Latin American standards, a devaluation of 25 per cent (later 45 per cent) is not much to get ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/19795
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  • 8
    Electronic Resource
    Electronic Resource
    Scientists seek support from Mexican public (1999)
    [s.l.] : Nature Publishing Group
    Nature 398 (1999), S. 7-9 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...Last year, Luis Herrera-Estrella thought he saw an opportunity to use his science to contribute to Mexico's economy. Herrera-Estrella, a plant biotechnologist at the Centre for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV), was one of several scientists invited ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/18754
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  • 9
    Electronic Resource
    Electronic Resource
    Customs delays drive researchers to smuggling (1999)
    [s.l.] : Nature Publishing Group
    Nature 398 (1999), S. 10-10 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Even for those fortunate scientists in Latin America who manage to obtain adequate funding, have bright graduate students to work with and fast Internet links connecting them to the world of science, a major obstacle remains on the road to first-rate research: fast access to equipment and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/18763
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  • 10
    Electronic Resource
    Electronic Resource
    Centre fights fixation with basic research (1999)
    [s.l.] : Nature Publishing Group
    Nature 398 (1999), S. 9-20 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The challenge of combining high-quality basic research with a mission to address the country's wider needs is embodied in the experience of UNAM's Nitrogen Fixation Research Centre, in Cuernavaca. The centre was founded in 1980 with the aim of studying the molecular basis of biological nitrogen ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/18760
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