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  • Other Sources  (6)
  • Oxford Univ. Press  (6)
  • 2020-2022
  • 2010-2014
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  • 1
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    Oxford Univ. Press
    In:  Journal of Neuropathology and Experimental Neurology, 58 (10). pp. 1029-1040.
    Publication Date: 2020-07-21
    Description: The ECM of astrocytic tumors promotes and modulates a variety of cell functions, such as cell attachment, migration, proliferation, survival, and signaling. Recent studies indicate that there are extensive and complex interactions among ECM molecules and that these can modify the function of the participating molecules, interactions between the proteoglycan, phosphacan, and the ECM protein, tenascin, being an example (63). In addition, on nonastrocytic cell types it has been shown that an integrin receptor and the cell surface proteoglycan CD44 recognize the same ECM ligand osteopontin, and thus modulate each others function (77, 86). Thus, interacting components in the ECM and cell surface receptors likely cooperate in regulating cell function and tumor invasion (59, 77, 80, 85-87, 95). As tumor cells are capable of remodeling their ECM through synthesis of ECM proteins and proteoglycans, as well as upregulating integrin receptors and proteoglycans on their cell surface, tumor cells are capable of controlling their own destiny. ECM molecules which are concentrated in blood vessels of malignant astrocytomas, such as tenascin-C and the 250-kDa CSPG (NG2), are potentially therapeutic targets.
    Type: Article , PeerReviewed
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  • 2
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    Oxford Univ. Press
    In:  Journal of Plankton Research, 21 (1). pp. 21-33.
    Publication Date: 2021-06-11
    Description: A total of 103 cephalopod paralarvae were sampled during June 1995 in Galician waters (NW Spain). Samples were taken with Bongo nets of 300 and 500 〈IMG SRC="/math/mu.gif"〉m mesh size at 48 sampling stations along 10 transverse transects ranging from 80 to 600 m water depth. Paralarvae of loliginid squid were most abundant (40%). The〈it〉Rhynchoteuthion〈/it〉 paralarvae of ommastrephid squid accounted for 25%, whereas sepiolids comprised 23% of the total sample. Octopods were scarce, at only 6.6%. Other cephalopod families accounted for 5%. Sizes of paralarvae ranged from 1.0 to 7.1 mm mantle length. Temperature and salinity distribution showed the presence of an intense upwelling during the survey period. The sampling data obtained before and during the presence of upwelled water off Rias of Pontevedra and Vigo (southern zone) showed that paralarval cephalopod abundance and distribution were closely related to the upwelled Eastern North-Atlantic Central Water (ENACW).
    Type: Article , PeerReviewed
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  • 3
    Publication Date: 2019-09-23
    Description: The seasonal development of oxygen concentrations in the deep water of a nearly permanently stratified station in Kiel Eight, which originates from inflows through the Great Belt and the Kattegat, was investigated. The bottom-water oxygen situation of an individual year was characterized by the apparent oxygen consumption rate from day 80 to day 260. The estimated consumption is poorly correlated with pelagic variables measured during the same year (winter-nutrient concentrations, DON, primary productivity, etc.). For the period 1979-1996, a significant correlation was found between oxygen consumption and average precipitation during the preceding 8 months (June-January). It is suggested that a considerable part of the production is transferred into the next year as particulate organic pool accumulated in, or on top of, the sediment rather than being immediately recycled.
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  • 4
    Publication Date: 2017-10-11
    Description: Osmium concentrations and isotopic signatures were measured in 28 primarily Holocene basalts (22 of which have been analyzed for Sr–Nd–Pb isotope composition), two carbonatites and two mantle xenoliths from the Canary Islands, Selvagen Grande and Madeira in the eastern North Atlantic. 187Os/188Os ratios in the basalts range from 0.129 to 0.183. The Os isotope systematics indicate that the basalts fall into three petrogenetic groups: (1) a ‘radiogenic’ group with high 187Os/188Os from 0.152 to 0.183; (2) an ‘unradiogenic’ group with low 187Os/188Os from 0.129 to 0.138; (3) an ‘intermediate’ group with 187Os/188Os between 0.139 and 0.151. The Os isotope systematics of the radiogenic group samples are consistent with minor contamination of the basalts by marine sediment. All samples in the unradiogenic group contain mantle xenoliths, and the unradiogenic Os can be explained by bulk assimilation of ≤ 5% mantle peridotite in the form of disaggregated xenoliths. The radiogenic and unradiogenic groups are also characterized by higher 87Sr/86Sr and 208Pb/204Pb but lower 143Nd/144Nd than samples with similar 206Pb/204Pb from the intermediate group, which is interpreted to reflect interaction of plume magmas with the lithospheric mantle. The intermediate group samples are believed to represent the isotopic signature of the mantle plume. The Os isotopic composition of the Canary plume is among the most radiogenic found in ocean island basalts, comparable with the endmember HIMU islands Mangaia and Tubuaii, but at significantly lower 206Pb/204Pb. The radiogenic Os and moderate 206Pb/204Pb signature of the Canary plume is consistent with a plume which contains 25–35% of relatively young (∼1.2 Ga) recycled oceanic crust. Variable degree of mixing of the Canary Island plume source with shallow depleted asthenosphere containing a component of Paleozoic oceanic crust produces the limited range in Os isotopic signatures observed in the Madeira and Canary Island basalts despite a large range in 206Pb/204Pb isotopic composition.
    Type: Article , PeerReviewed
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  • 5
    Publication Date: 2021-06-16
    Description: Statolith microstructure was studied in hatchlings of deepwater-spawned gonatid squid Gonatus onyx, caught between 1350 and 1420 m over a bottom depth of 2100 m in the San Clemente Basin off San Diego, California. It was found that the shape and size of the hatchling statolith were similar to those of the first-check statolith observed in paralarvae and small juveniles of G.onyx. The inner part of the bipartite postnuclear zone (= first-check statolith) is formed during late embryo-genesis, and the first check within the statolith microstructure must be considered as a starting point of increment counting for age estimation of Gonatus
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  • 6
    Publication Date: 2021-06-17
    Description: Length–frequency analysis was employed to resolve multiple cohorts in the Loligo forbesi population from coastal waters to the west of Scotland. In both male and female squid two principal cohorts were identified, recruiting to the fished population in April and November. Both cohorts spawned during the winter months (November to April), producing a single extended spawning season, with the April recruits of larger size at spawning than the November recruits. In the males the April recruits appeared to separate into two cohorts of different growth rates, thus producing three rather than two sizes at maturity. The abundance of L. forbesi was low during the summer months, indicating that the squid had moved outside the range of the fishery, perhaps into deeper water. Abundance declined during the spawning season, which is interpreted as post-spawning mortality. Abundance declined earlier in the males than females, producing a female biased sex ratio during most of the spawning season. The two periods of recruitment are not compatible with a 1 year life cycle and single extended spawning season and explanations of this are discussed.
    Type: Article , PeerReviewed
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