Publication Date:
1992-06-05
Description:
Knowledge of zoonotic transmission cycles is essential for the development of effective strategies for disease prevention. The enzootiology of Lyme disease in California differs fundamentally from that reported from the eastern United States. Woodrats, not mice, serve as reservoir hosts, and Ixodes neotomae, a nonhuman-biting tick, maintains the agent of Lyme disease, Borrelia burgdorferi, in enzootic cycles. The western black-legged tick, Ixodes pacificus, is the primary vector to humans, but it appears to be an inefficient maintenance vector. Isolates of B. burgdorferi from California exhibit considerable antigenic heterogeneity, and some isolates differ strikingly from isolates recovered from this and other geographic regions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brown, R N -- Lane, R S -- AI22501/AI/NIAID NIH HHS/ -- U50/CCU906594/PHS HHS/ -- New York, N.Y. -- Science. 1992 Jun 5;256(5062):1439-42.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Entomological Sciences, University of California, Berkeley 94720.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1604318" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Antibodies, Monoclonal
;
Bacterial Proteins/analysis
;
Borrelia/isolation & purification
;
Borrelia burgdorferi Group/isolation & purification/*pathogenicity
;
California
;
Dipodomys/parasitology
;
Disease Reservoirs
;
Larva
;
Lyme Disease/*transmission
;
Mice/parasitology
;
Rodentia/*parasitology
;
Ticks/*parasitology
;
United States
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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