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  • Articles  (5)
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  • Laser  (5)
  • Springer  (5)
  • Annual Reviews
  • PANGAEA
  • 1990-1994  (5)
  • 1980-1984
  • 1991  (5)
  • Technology  (5)
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  • Articles  (5)
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  • Springer  (5)
  • Annual Reviews
  • PANGAEA
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  • 1990-1994  (5)
  • 1980-1984
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  • 1
    Electronic Resource
    Electronic Resource
    In vitro effects of CO2 laser irradiation on platelets: Influence of aspirin (1991)
    Springer
    Lasers in medical science 6 (1991), S. 15-21 
    Details
    ISSN: 1435-604X
    Keywords: Laser ; Platelets ; Aspirin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Laser angioplasty involves intravascular laser irradiation which may affect platelets and aggregation. In this study we examined the in vitro effects of different energy doses and modes of CO2 laser irradiation on the platelet number, function and ultrastructure. Since aspirin is used in many patients suffering from coronary artery disease, the consequences of laser irradiation on aspirin-treated platelets were studied as well. We found that CO2 laser irradiation causes a dose-response reduction of the platelet number that is most pronounced with high energy-short duration irradiation, and a dose-response reduction in platelet aggregation which is independent of the mode of irradiation. Pretreatment with aspirin does not change the effects of laser irradiation on platelet number, while aggregation is reduced only at relatively high energy doses. Electron microscopy revealed significant intracellular injury following low energy irradiation, while progressive damage to membranes occurred in a dose-response mode, both in untreated and aspirin-treated platelets. The clinical application of our findings should be done cautiously since important in vivo factors, such as the effect of laser irradiation on the vessel wall and coagulation system, were not studied.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02042641
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  • 2
    Electronic Resource
    Electronic Resource
    Laser angioplasty versus balloon angioplasty: The need for imaging (1991)
    Springer
    Lasers in medical science 6 (1991), S. 223-233 
    Details
    ISSN: 1435-604X
    Keywords: Angioplasty ; Recanalization ; Laser ; Balloon ; Intravascular ultrasound ; Restenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract The current state of clinical laser angioplasty is reviewed. Compared to balloon dilation at the beginning of the past decade, both peripheral and coronary laser angioplasty devices produce better results. Compared to current balloon angioplasty techniques, however, laser angioplasty does not seem to offer improved initial or long term results. Intravascular ultrasound imaging may help to improve laser ablation of atherosclerotic plaque. It remains to be established, however, whether precise debulking of the obstruction will result in a reduced restenosis rate compared to balloon angioplasty.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02030875
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  • 3
    Electronic Resource
    Electronic Resource
    Laser systems for cardiovascular applications (1991)
    Springer
    Lasers in medical science 6 (1991), S. 255-259 
    Details
    ISSN: 1435-604X
    Keywords: Laser ; Angioplasty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Different laser systems have been proposed for angioplasty. A brief overview is given in order to describe the basic concepts which characterize each case. The results of a comparison are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02030878
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  • 4
    Electronic Resource
    Electronic Resource
    X-Ray- and catheter-guided intracardial laser photocoagulation of arrhythmogenic substrates (1991)
    Springer
    Lasers in medical science 6 (1991), S. 367-370 
    Details
    ISSN: 1435-604X
    Keywords: Arrhythmia ; Cardiology ; Cardiovascular surgery ; Catheter ; Heart ; Laser ; Mapping ; Photocoagulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Cardiac arrhythmias resistant to drug treatment and correlated to an arrhythmogenic anatomic structure can be treated in several cases by surgical intervention. A further method of treatment is the percutaneous, ECG mapping-guided catheter ablation with either direct current (DC) or radio frequency (RF) ablation of localized arrhythmogenic foci. These methods overcome some complications inherent to open surgery to the heart; DC ablation, however, often induces further arrhythmias or ventricular or auricular fibrillation, while RF ablation shows only little success. In the method presented here disturbing electric effects are avoided by laser photocoagulation via a transcatheter quartz fibre. An electrode/laser catheter recently developed simultaneously allows for a mapping-guided localization of arrhythmogenic substrates and their percutaneous transluminal and intracardial deactivation. An anchoring mechanism at the catheter's tip keeps it in place during the treatment. This mechanism also prevents contact of the quartz fibre to the endomyocardium in order to avoid destruction of the fibre tip due to local overheating of the myocardium. A Nd-YAG laser (wavelength 1.064μm) delivers pulses of 5–10 s and a power of 10–15 W at the tip of a quartz fibre with a core diameter of 400μm. The corresponding parameter or irradiation of the myocardium are power densities of 700–1500 W cm−2 and energy densities of 8–15 kJ cm−2. In dog hearts lesions 2–10 mm in diameter and up to 11 mm in depth were obtained. Simultaneously registered electrocardiograms show that primarily induced arrhythmias lasted only for about 3 min but could not again be observed during the 2–3 months follow-up. Crater formation or perforation of the myocardium always could be avoided by an ECG-controlled laser irradiation. This indicates the safety and efficacy of the laser method for intracardial intervention in arrhythmogenic substrates. Clinical tests have been started recently.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02030895
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  • 5
    Electronic Resource
    Electronic Resource
    A tool for the evaluation of colour in port wine stains (1991)
    Springer
    Lasers in medical science 6 (1991), S. 49-52 
    Details
    ISSN: 1435-604X
    Keywords: Port wine stains ; Naevus flammeus ; Colour ; Colourimetry ; Laser
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract A simple method for immediate comparison of the aesthetic results of laser treatment of port wine stains has been developed. This method could easily be implemented in the offices of laser specialists throughout the world. The method consists of a colour strip that is viewed together with the lesion. The colours have been chosen from the MUNSELL standard colour system. After extensive testing eight colours were chosen that appear visually equally spaced and represent the various colours of port wine stains before and during their treatment. Using this standard would allow a much more objective analysis of the results of different techniques and lasers. Just as importantly it gives the patients an objective indication of their progress during treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02042646
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