Electronic Resource
Springer
Pharmacy world & science
10 (1988), S. 101-116
ISSN:
1573-739X
Keywords:
Chemistry
;
Chromatography
;
Etoposide
;
Immunoassay
;
Metabolism
;
Podophyllotoxin
;
Pharmacokinetics
;
Teniposide
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Etoposide (VP 16-213) and teniposide (VM 26) are semisynthetic epipodophyllotoxin derivatives active against a variety of tumours. The clinical efficacy has led to an increasing interest in these compounds. This review presents information on the mechanism of action, biochemical pharmacology, bioanalysis, metabolism and pharmacokinetics of etoposide and teniposide.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01959294
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