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  • American Association for the Advancement of Science (AAAS)  (25)
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  • 1
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    American Association for the Advancement of Science (AAAS)
    Publikationsdatum: 1986-01-31
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Soloway, A H -- New York, N.Y. -- Science. 1986 Jan 31;231(4737):442.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3941905" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adult ; Child ; Drug Therapy/*standards ; *Government Agencies ; Humans ; *Patient Participation ; Social Responsibility ; United States
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Publikationsdatum: 1986-12-12
    Beschreibung: When isolated adult oligodendrocytes adhere to a substratum myelinogenesis occurs. Investigation of the mechanism by which this happens indicated that the oligodendrocyte-substratum interaction activated protein kinase C-dependent phosphorylation of myelin basic protein and promoted the synthesis of myelin basic protein. In addition, when agents that activate protein kinase C (second messenger diacylglycerol or a tumor-promoting phorbol ester) were added to nonattached oligodendrocytes, they mimicked the influence of the substratum by inducing phosphorylation of myelin basic protein; and reagents that increase cellular adenosine 3', 5'-monophosphate (cyclic AMP) inhibited phosphorylation of myelin basic protein. Thus, at least in vitro, the interaction between oligodendrocytes and the substratum may mediate myelinogenic events, and phosphorylation of myelin basic protein may be an early requirement in the sequence of steps that ultimately results in myelin formation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vartanian, T -- Szuchet, S -- Dawson, G -- Campagnoni, A T -- GM-07183/GM/NIGMS NIH HHS/ -- HD-04583/HD/NICHD NIH HHS/ -- HD-06426/HD/NICHD NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1986 Dec 12;234(4782):1395-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2431483" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): 1-Methyl-3-isobutylxanthine/pharmacology ; Adult ; Calcimycin/pharmacology ; Cell Adhesion ; Colforsin/pharmacology ; Cyclic AMP/metabolism ; Enzyme Activation ; Humans ; Myelin Basic Protein/*metabolism ; Neuroglia/*cytology ; Oligodendroglia/*cytology ; Phosphorylation ; Protein Kinase C/*metabolism ; Tetradecanoylphorbol Acetate/pharmacology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
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    American Association for the Advancement of Science (AAAS)
    Publikationsdatum: 1986-10-31
    Beschreibung: From the postwar high of 3.8 births per woman at the peak of the baby boom, the total fertility rate in the United States has fallen to 1.8, where it has remained unchanged for nearly a decade. This below-replacement level of fertility has, in recent decades, characterized most Western countries, some of which have shown declines to well below 1.5 births per woman. Were it not for the continued infusion of immigrants, the U.S. population, which already shows the aging characteristic of low fertility, would stop growing and begin to decline before the middle of the next century. The low fertility in the United States has been accomplished by a postponement of marriage and by the widespread use of contraception, with heavy reliance on surgical sterilization as a contraceptive method. Judging from the experience of other Western countries and from our own historical experience of two centuries of fertility decline interrupted only by the baby boom, as well as from the absence of social trends that would counteract those contributing to that decline, the prognosis is for a continued low level of fertility in the United States.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Westoff, C F -- New York, N.Y. -- Science. 1986 Oct 31;234(4776):554-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3532324" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adolescent ; Adult ; *Birth Rate ; Contraception/history ; Ethnic Groups ; Female ; Fertility ; Forecasting ; History, 20th Century ; Humans ; Population Dynamics ; Population Growth ; Pregnancy ; Pregnancy in Adolescence ; United States
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Publikationsdatum: 1986-03-07
    Beschreibung: A sensitive radioimmunoassay for atrial natriuretic peptide was used to examine the relation between circulating atrial natriuretic peptide and cardiac filling pressure in normal human subjects, in patients with cardiovascular disease and normal cardiac filling pressure, and in patients with cardiovascular disease and elevated cardiac filling pressure with and without congestive heart failure. The present studies establish a normal range for atrial natriuretic peptide in normal human subjects. These studies also establish that elevated cardiac filling pressure is associated with increased circulating concentrations of atrial natriuretic peptide and that congestive heart failure is not characterized by a deficiency in atrial natriuretic peptide, but with its elevation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burnett, J C Jr -- Kao, P C -- Hu, D C -- Heser, D W -- Heublein, D -- Granger, J P -- Opgenorth, T J -- Reeder, G S -- New York, N.Y. -- Science. 1986 Mar 7;231(4742):1145-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2935937" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adult ; Aged ; Atrial Natriuretic Factor/*blood ; Cardiovascular Diseases/blood ; Female ; Heart Failure/*blood ; Hemodynamics ; Humans ; Male ; Middle Aged ; Radioimmunoassay
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Publikationsdatum: 1986-04-25
    Beschreibung: Immunoreactive oxytocin and neurophysin were identified and measured by radioimmunoassay in human thymus extracts. Serial dilutions of extracts paralleled the appropriate standard curves. Thymus-extracted oxytocin and neurophysin eluted in the same positions as reference preparations on Sephadex G-75. Authenticity of oxytocin was confirmed by biological assay and high-performance liquid chromatography analysis. In most instances, thymus contents of oxytocin and neurophysin were far greater than those expected from known circulating concentrations and declined with increasing age. The molar ratio of oxytocin to neurophysin in thymus was similar to that found in the hypothalamo-neurohypophyseal system, which strongly suggested with the other data a local synthesis of oxytocin. These findings indicate the presence of neurohypophyseal peptides in the human thymus and further support the concept of a neuroendocrine function integrated in an immune structure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Geenen, V -- Legros, J J -- Franchimont, P -- Baudrihaye, M -- Defresne, M P -- Boniver, J -- New York, N.Y. -- Science. 1986 Apr 25;232(4749):508-11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3961493" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adult ; Age Factors ; Child ; Chromatography, Gel ; Chromatography, High Pressure Liquid ; Female ; Humans ; Infant, Newborn ; Male ; Middle Aged ; Myasthenia Gravis/physiopathology ; Neurophysins/*analysis/isolation & purification/physiology ; Oxytocin/*analysis/isolation & purification/physiology ; Radioimmunoassay ; Thymus Gland/*analysis/physiology/physiopathology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
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    American Association for the Advancement of Science (AAAS)
    Publikationsdatum: 1986-09-26
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1986 Sep 26;233(4771):1377-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3749882" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adolescent ; *Adolescent Behavior ; Adult ; *Crime ; Government Agencies ; Humans ; Middle Aged ; United States
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
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    American Association for the Advancement of Science (AAAS)
    Publikationsdatum: 1986-09-19
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1986 Sep 19;233(4770):1249-51.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3749875" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adolescent ; Adult ; Female ; Humans ; *Mmpi ; Male ; United States
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
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    American Association for the Advancement of Science (AAAS)
    Publikationsdatum: 1986-09-26
    Beschreibung: Direct evidence on age patterns of infecundity and sterility cannot be obtained from contemporary populations because such large fractions of couples use contraception or have been sterilized. Instead, historical data are exploited to yield upper bounds applicable to contemporary populations on the proportions sterile at each age. Examination of recent changes in sexual behavior that may increase infecundity indicates that sexually transmitted infections, the prime candidate for hypothesized rises in infertility, are unlikely to have added to infecundity to any great extent. These results imply that a woman in a monogamous union faces only moderate increases in the probability of becoming sterile (or infecund) until her late thirties. Nevertheless, it appears that recent changes in reproductive behavior were guaranteed to result in the perception that infecundity is on the rise.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Menken, J -- Trussell, J -- Larsen, U -- HD11720/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1986 Sep 26;233(4771):1389-94.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3755843" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adolescent ; Adult ; Age Factors ; *Aging ; Female ; *Fertility ; Humans ; Infertility, Female/*epidemiology ; Infertility, Male/*epidemiology ; Male ; Marriage ; Middle Aged ; United States
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
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    American Association for the Advancement of Science (AAAS)
    Publikationsdatum: 1986-11-21
    Beschreibung: Issues regarding the use of epidemiology in drug abuse research are discussed and systems for monitoring national trends and identifying risk factors are described. Data indicate a general decline in marijuana use among youth, a cohort aging effect among heroin and marijuana users, and increased prevalence and health consequences associated with cocaine use.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kozel, N J -- Adams, E H -- New York, N.Y. -- Science. 1986 Nov 21;234(4779):970-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3490691" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Acquired Immunodeficiency Syndrome/complications ; Adolescent ; Adult ; Child ; Cocaine ; Epidemiologic Methods ; Female ; Heroin ; Humans ; Male ; Marijuana Abuse/epidemiology ; Population Surveillance ; Risk ; Substance-Related Disorders/*epidemiology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
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    American Association for the Advancement of Science (AAAS)
    Publikationsdatum: 1986-01-10
    Beschreibung: Red blood cells that are infected with the malaria parasite Plasmodium falciparum express new antigens on their surface. In a study of these antigens in the erythrocytes of naturally infected children in the Gambia, an antibody-mediated agglutination assay revealed an extreme degree of antigenic diversity. Serum samples from each of ten children in the convalescent stage of malaria infection reacted with infected cells from the same child but generally not with infected cells from the other children. The Gambian children's erythrocytes also expressed shared determinants: sera from Gambian adults often reacted with the surface of infected cells from all of the children and were shown by adsorption and elution experiments to contain antibodies that recognized several isolates. Conserved determinants exposed on infected erythrocytes may be important for development of antimalarial immunity either naturally or through vaccination.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marsh, K -- Howard, R J -- New York, N.Y. -- Science. 1986 Jan 10;231(4734):150-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2417315" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adult ; Agglutination Tests ; Antigens, Protozoan/*immunology ; Child ; *Epitopes ; Erythrocytes/immunology/*parasitology ; Gambia ; Humans ; Malaria/*immunology ; Plasmodium falciparum
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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