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  • Articles  (8)
  • Other Sources
  • Osteoporosis  (8)
  • Springer  (8)
  • American Association for the Advancement of Science
  • American Geophysical Union
  • American Institute of Physics (AIP)
  • Blackwell Publishing Ltd
  • Institute of Physics
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  • 2020-2022
  • 2000-2004
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  • 1980-1984  (8)
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  • 1984  (8)
  • Physics  (8)
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  • Electrical Engineering, Measurement and Control Technology
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  • Articles  (8)
  • Other Sources
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  • Springer  (8)
  • American Association for the Advancement of Science
  • American Geophysical Union
  • American Institute of Physics (AIP)
  • Blackwell Publishing Ltd
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  • 2020-2022
  • 2000-2004
  • 1995-1999
  • 1980-1984  (8)
  • 1950-1954
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  • Physics  (8)
  • Natural Sciences in General
  • Technology
  • Electrical Engineering, Measurement and Control Technology
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  • 1
    Electronic Resource
    Electronic Resource
    Bone involution decrease in exercising middle-aged women (1984)
    Springer
    Calcified tissue international 36 (1984), S. S129 
    Details
    ISSN: 1432-0827
    Keywords: Bone mass ; Exercise ; Aging women ; Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Physical activity is an important stimulus in the prevention of bone involution. Bilateral bone mineral mass and width of the radius, ulna, and humerus were measured by single photon absorptiometry on 200 women between the ages of 35 and 65 over a 3–4 year period. Two groups were formed: 80 in a control group and 120 in a physical activity group exercising 45 min/day, 3 days/week. The control and physical activity groups were similar in age, height, weight, and level of physical fitness at the beginning of the study. The control group lost bone mineral mass at a rate similar to that of the general population. The left radius bone mineral declined 2.44% per year. Similar rates of decline were observed in the other bones measured. The physical activity group increased in fitness by 13% in the first year of the study. The bone mineral mass of the exercise group declined the first year and then increased; thereby the bone mineral data for the exercise group was analyzed in two sets. During the first year of the program, a decline of 3.77% in bone mineral mass of the left radius, a significantly greater loss than that of the control group, was observed. Decline rates were similar in the other bones measured. In the second and third years, bone mineral mass of the left radius increased by 1.39% per year, and the rate of change was significantly different from that of the control group. There were similar increases in the other bones measured. The data from this study support the importance of physical activity in the prevention of bone mineral loss in the aging female.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02406146
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  • 2
    Electronic Resource
    Electronic Resource
    Fluoride absorption: The influence of gastric acidity (1984)
    Springer
    Calcified tissue international 36 (1984), S. 302-307 
    Details
    ISSN: 1432-0827
    Keywords: Metabolism ; pH ; Fluorosis ; Osteoporosis ; Toxicity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The influence of gastric acidity on the absorption of intragastrically administered fluoride was investigated in rats. Intact animals were pretreated with atropine or cimetidine to reduce gastric acid secretion or were given fluoride in NaHCO3 to reduce the acidity of the gastric contents. Compared with pentagastrin-treated animals or animals that received fluoride in 0.1 N HCl, their rate of fluoride absorption was markedly reduced as judged by lower plasma fluoride concentrations and areas under the time-plasma concentration curves, especially during the first hour after dosing. In crossover studies with the stomachs isolatedin situ, fluoride absorption was at least 50% faster from a pH 2.1 buffer compared with its absorption from a pH 7.1 buffer. The findings are consistent with the hypothesis that fluoride is absorbed from the gastric lumen principally as the undissociated molecule, HF. The results may contribute to a more complete understanding of acute fluoride toxicity, the development of dental fluorosis and, perhaps, the use of fluoride in the treatment of osteoporosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405334
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  • 3
    Electronic Resource
    Electronic Resource
    The effect of bendroflumethiazide and hydrochlorothiazide on the rate of dissolution of calcium hydroxyapatite (1984)
    Springer
    Calcified tissue international 36 (1984), S. 431-434 
    Details
    ISSN: 1432-0827
    Keywords: Bendroflumethiazide ; Hydrochlorothiazide ; Calcium hydroxyapatite ; Hydrolysis ; Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Inhibition of dissolution of calcium hydroxyapatite in the presence of bendroflumethiazide, Centyl®, and of hydrochlorothiazide has been investigated. The former compound has a pronounced larger inhibitory effect than the latter. The trifluormethyl group in bendroflumethiazide has been shown to hydrolyze, with the release of fluoride and hydrogen ions, presumably forming a carboxylic acid. The inhibitory effect of hydrolyzed bendroflumethiazide is found to be similar to the effect of a potassium fluoride solution with the same fluoride ion concentration, as measured by a fluoride selective ion electrode.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405355
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  • 4
    Electronic Resource
    Electronic Resource
    Total body and regional bone mineral by dual-photon absorptiometry in metabolic bone disease (1984)
    Springer
    Calcified tissue international 36 (1984), S. 8-13 
    Details
    ISSN: 1432-0827
    Keywords: Osteoporosis ; Renal osteodystrophy ; Fractures ; Bones and bone disease ; Absorptiometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Dual-photon absorptiometry (153Gd) was used to measure bone mineral of the total body and major anatomical areas. Patients with osteoporosis (♂=11, ♀=18) and with renal osteodystrophy (n=17) were significantly below (20%) normal females (n=72) and males (n=13) at most sites. In the osteoporotic patients, but not the renal patients, there was preferential osteopenia of the spine. Bone loss in all anatomical areas became evident after the menopause with an annual loss rate of about 0.7%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405287
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  • 5
    Electronic Resource
    Electronic Resource
    Functional strain as a determinant for bone remodeling (1984)
    Springer
    Calcified tissue international 36 (1984), S. S56 
    Details
    ISSN: 1432-0827
    Keywords: Mechanical strain ; Bone remodeling ; Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Mechanical function has always been acknowledged to have a significant, continuing but hitherto unquantified influence on bone remodeling. The structural objective of this relationship is presumably to ensure that, at each location throughout the skeleton, there is sufficient bone tissue, appropriately placed, to withstand functional load-bearing without damage. The architectural modifications necessary to achieve and maintain this structural competence are made by the coordinated remodeling activity of populations of osteoblasts and osteoclasts. The specific structure-function objectives at each location remain undefined, as are the mechanisms by which tissue loading is transduced into cellular control. The remodeling responses following a variety of experimental alterations in bones' strain environment are presented. Their significance to the process of remodeling control is discussed, and a scheme for the interaction of mechanical and hormonal influences proposed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02406134
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  • 6
    Electronic Resource
    Electronic Resource
    Preliminary observations of a form of coherence therapy for osteoporosis (1984)
    Springer
    Calcified tissue international 36 (1984), S. 341-343 
    Details
    ISSN: 1432-0827
    Keywords: Osteoporosis ; Coherence Therapy ; Histomorphometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Five patients suffering from osteoporosis were subjected to from three to eight cycles of a form of Coherence Therapy for Osteoporosis (1) used at this center. Assessment of the patients' trabecular bone remodeling activity as measured by histomorphometric analyses of trans-iliac crest bone biopsies showed a marked improvement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405341
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  • 7
    Electronic Resource
    Electronic Resource
    Racial differences in calcitonin and katacalcin (1984)
    Springer
    Calcified tissue international 36 (1984), S. 725-728 
    Details
    ISSN: 1432-0827
    Keywords: Race ; Osteoporosis ; Calcitonin ; Katacalcin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Profound racial differences exist in the incidence of osteoporosis, particularly in women. To investigate possible underlying reasons for this, we have measured the circulating levels of calcitonin (iCT), a bone-protecting hormone, and its flanking peptide, katacalcin (iKC), in black Gambian and white British populations. Whilst sex differences in both peptides were observed, with males having higher levels than females, the most striking finding was that white women have the lowest iCT levels. This important observation may explain, at least in part, why osteoporosis is particularly a disease of white, postmenopausal women.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405396
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  • 8
    Electronic Resource
    Electronic Resource
    Effects of 1,25(OH)2D3 on bone tissue in the rabbit: Studies on fracture healing, disuse osteoporosis, and prednisone osteoporosis (1984)
    Springer
    Calcified tissue international 36 (1984), S. 591-595 
    Details
    ISSN: 1432-0827
    Keywords: Fracture ; (Glucocorticoid ; 1,25(OH)2D3 ; Osteoporosis ; Rabbit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary A closed tibial fracture, which was controlled by an intramedullary stainless steel pin, was created in 16 rabbits. Eight rabbits were treated with 75 ng of 1,25(OH)2D3 daily as subcutaneous (s.c.) injections. After three weeks, the fractured tibia resisted a force of 101,7±21.0 Newtons in the control group and 57.3±8.0 Newtons in animals given 1,25(OH)2D3 (m±SE,P〈0.05). In another group of eight rabbits, the left hindleg was immobilized in a plastic splint. Four rabbits were given 75 ng of 1,25(OH)2D3/day s.c. and the effect of immobilization was studied on the calcaneus. Bone ash/cm3 of the calcaneus on the immobilized side was decreased by 11±2% in control rabbits and by 20±2% in the group treated with 1,25(OH)2D3 indicating a more advanced immobilization osteoporosis (m±SE,P〈0.05), which was also demonstrated by studies of bone density. Eighteen rabbits were used in a study of the effects of 1,25(OH)2D3 on the development of prednisolone osteoporosis. The dose of prednisolone was 2.5 mg per day, given by the oral route. After four months, the density of the femur was 1.53±0.02 g/cm2 in control rabbits and 1.42±0.01 in prednisolonetreated animals (P〈0.01). In rabbits additionally given 1,25(OH)2D3, the mean value for bone density was further lowered (n.s.). It appears that 1,25(OH)2D3 exaggerates disuse osteoporosis and prednisolone osteoporosis and impairs fracture healing in rabbits. These results differ from what has been shown earlier with 1,25(OH)2D3 treatment in the rat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405372
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