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  • Artikel  (4)
  • hyperthermia  (4)
  • Wiley-Blackwell  (4)
  • Copernicus
  • National Academy of Sciences
  • 2010-2014
  • 1980-1984  (4)
  • 1945-1949
  • 1925-1929
  • 1983  (4)
  • Physik  (4)
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  • Artikel  (4)
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  • Wiley-Blackwell  (4)
  • Copernicus
  • National Academy of Sciences
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  • 2010-2014
  • 1980-1984  (4)
  • 1945-1949
  • 1925-1929
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  • 1
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 4 (1983), S. 115-122 
    ISSN: 0197-8462
    Schlagwort(e): microwave biological effects ; hyperthermia ; B lymphocytes ; capping ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Physik
    Notizen: Normal mouse B lymphocytes were tested for the ability to cap plasma membrane antigenantibody complexes following exposure to 2.45-GHz continuous wave (CW) microwaves at power densities up to 100 mW/cm2 (45 W/kg specific absorption rate), at 37, 41, and 42.5 °C. After a 30-minute treatment, the irradiated cells and the nonirradiated controls were tested for capping by the direct immunofluorescence technique. First, the cells were incubated for nine minutes at 37 °C with fluorescein isothiocyanate-conjugated goat antimouse immunoglobulin. After fixing and washing, the percentage of capped cells was determined under a fluorescence microscope. The results show that for the nonirradiated controls, capping is reduced from 90% at 37 °C, to 52% 41 °C. to less than 5% for cells that were pretreated at 42.5 °C. There was no significant difference between the microwave-treated cells and the controls when both were maintained at the same temperature. In another experiment, there was no significant difference in the percentage of capping between controls and cells that were exposed to microwave radiation during capping, when the temperature in both preparations was kept at 38.5 °C. The results demonstrate that B-lymphocyte capping is sensitive to temperature in the range that is proposed for use in tumor therapy.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 4 (1983), S. 157-165 
    ISSN: 0197-8462
    Schlagwort(e): amplitude-modulated RF fields ; hyperthermia ; B lymphocytes ; capping ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Physik
    Notizen: B lymphocytes collected from normal ICR Swiss mouse spleens were exposed in vitro in a Crawford cell to 147-MHz radiofrequency (RF) radiation, amplitude modulated by a 9-, 16-, or 60-Hz sine wave. The power densities ranged between 0.11 and 48 mW/cm2. The irradiated samples and the controls were maintained at 37 °C or 42 °C, with temperature variations less than 0.1 °C. Immediately after a 30-minute exposure, the distribution of antigen-antibody (Ag—Ab) complexes on the cell surface was evaluated at 37 °C by immunofluorescence. Under normal conditions (37 °C, no RF), Ag—Ab complexes are regrouped into a polar cap by an energy-dependent process. Our results demonstrate that the irradiated cells and the nonirradiated controls capped Ag—Ab complexes equally well after exposure at 37 °C. Capping was equally inhibited at 42 °C in both the controls and irradiated cells. No statistically significant differences in capping were observed between the RF-exposed and control samples at any of the modulation frequencies and power densities employed as long as both preparations were maintained at the same temperature.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 4 (1983), S. 249-255 
    ISSN: 0197-8462
    Schlagwort(e): radiofrequency radiation ; 27.12 MHz ; hyperthermia ; teratology ; rat ; embryo ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Physik
    Notizen: Five groups of pregnant Sprague-Dawley rats were either sham exposed or were irradiated in a 27.12-MHz radiofrequency (RF) field at 55 A/m and 300 V/m on gestation day 9. The absorbed power (approximately 11 W/kg) caused a relatively rapid increase in the rat's colonic temperature. Rats in group I were sham irradiated for 2.5 h at 0 A/m, 0 V/m. In group II RF irradiation was terminated after the rat's colonic temperature reached 41.0 °C. In group III the 41.0- °C temperature was maintained an additional 15 min by varying the field strength. At both temperatures the teratogenic and embryotoxic effects of the RF-induced hyperthermia increased as the exposure duration increased, but the increase was especially noticeable at 42.0 °C. The results indicate that the teratogenic and embryotoxic effects of RF-induced hyperthermia are related to both the temperature of the dam during exposure and the length of time the dam's temperature remains elevated.
    Zusätzliches Material: 2 Tab.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 4 (1983), S. 55-62 
    ISSN: 0197-8462
    Schlagwort(e): 2880-MHz microwaves ; submaxillary salivary gland ; Na+ ; K+ ; Ca2+ ; flame photometry ; hyperthermia ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Physik
    Notizen: Na+, K+, and Ca2+ concentrations in the blood serum and submaxillary salivary gland (SSG) were investigated in adult, male rats exposed to 2880-MHz microwaves modulated with 1.5-μs pulses at a pulse repetition rate of 1000 Hz or in a hyperthermal environment. Rats were exposed, one at a time, for 30 min to microwaves producing a specific absorption rate (SAR) of: 4.2, 6.3,6.8,8.4, 10.8, or 12.6 W/kg, or were sham exposed under similar environmental conditions. In a second series, one group of rats was exposed singly for 15, 30, or 60 min to microwaves producing an SAR of 9.5 W/kg and other rats were exposed for similar periods at 40 °C; and 10 rats were sham exposed. Flame photometric analysis indicated that the thresholds of microwave radiation required to induce a change in Na+, K+, and Ca2+ concentrations in the salivary glands are 6.8, 6.8, and 6.3 W/kg, respectively. The directions of Na+, K+, and Ca2+ ion shifts in exposed rats' salivary glands are similar, whether affected by microwaves or hyperthermia. Greater changes in Na+ and K+ concentrations in SSG of rats exposed to microwaves for 15 and 30 min were found than in those exposed at 40 °C. On the other hand, exposure to hyperthermia at 40 °C or to microwaves for 1 h caused Na+ concentration to be increased by 68.7 and 59.5% and K+ concentration to be decreased by 29.6 and 21.7%, respectively.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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