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  • 1
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Atoms. ; Molecules. ; Biotechnology. ; Atomic, Molecular and Chemical Physics.
    Description / Table of Contents: Photonic crystals for biomolecule sensing applications -- Recent advances in Surface Plasmon Resonance for biosensing applications and future prospects -- Surface-enhanced Raman Scattering for biology and medicine -- Nanophotonic techniques for single cell analysis -- Biointerface Characterization by Nonlinear Optical Spectroscopy -- Chemiluminescence and its biomedical applications -- Luminescent Conjugated Polymer Dots for Biomedical Applications -- Dark-Field Hyperspectral Imaging (DF-HSI) Modalities for Characterization of Single Molecule and Cellular Processes -- Additive Manufacturing Technologies based on Photopolymerization.
    Abstract: This book summarizes the latest advances in nanophotonics for biomedical applications, including biomolecular sensing and imaging, additive fabrications, and biophotonics. The engineering of nanophotonics will have significant impacts on the life sciences and medicine alike. Given its scope, the book offers a valuable asset for researchers, scientists, engineers, and graduate students in the fields of biomedical engineering, electrical engineering, materials sciences, optics, biology, and medicine.
    Type of Medium: Online Resource
    Pages: V, 282 p. 160 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811561375
    DDC: 660.6
    Language: English
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  • 2
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botany. ; Plant genetics. ; Plant ecology. ; Plant Science. ; Plant Genetics. ; Plant Ecology.
    Description / Table of Contents: Preface -- Acknowledgement -- Chapter 1. Taxonomic History -- Chapter 2. Morphology -- Chapter 3. Biology -- Chapter 4. Economic Importance -- Chapter 5. Phylogeny, classification, and biogeography -- Chapter 6. Taxonomic revision -- Chapter 7. Conservation status.
    Abstract: This book provides essential information on the morphology, biology, phytochemistry, pharmaceutical prospects, evolution, phylogeny, biogeography, and taxonomy of Paris (Melanthiaceae), a morphologically distinctive plant genus with great economic importance. Since the establishment of this genus, 70 species and 24 subspecific taxa have been described, resulting in considerable confusion in species delimitation. In this book, the taxonomy of all described taxa is carefully revised. Based on multi-disciplinary evidences, a revised classification system of Paris containing five sections is outlined. Every species is provided with a concise but diagnostic description, a color illustration, photographs that highlight distinguishing characters, examined specimens and distribution range. The interspecific relationships are clarified with an identification key. This monograph offers taxonomists, evolutionary biologists, ecologists, horticulturalists, phytochemists, and practitioners a thorough and up-to-date overview about this interesting plant group. It is equally valuable for undergraduate and graduate students, teachers and professionals engaged in related fields.
    Type of Medium: Online Resource
    Pages: XIII, 203 p. 134 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811579035
    DDC: 580
    Language: English
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  • 3
    Keywords: Conservation biology. ; Ecology . ; Biotic communities. ; Population biology. ; Animal migration. ; Conservation Biology. ; Theoretical and Statistical Ecology. ; Community and Population Ecology. ; Animal Migration.
    Description / Table of Contents: Chapter 1. The conservation issue -- Chapter 2. Development of hierarchical spatial models for assessing ungulate abundance and habitat relationships -- Chapter 3. Model-based assessment of ungulate-habitat relationships -- Chapter 4. Assessing threats to ungulates and management responses -- Chapter 5. Conservation of tropical forest ungulates: the way forward.
    Abstract: Large ungulates in tropical forests are among the most threatened taxa of mammals. Excessive hunting, degradation of and encroachments on their natural habitats by humans have contributed to drastic reductions in wild ungulate populations in recent decades. As such, reliable assessments of ungulate-habitat relationships and the spatial dynamics of their populations are urgently needed to provide a scientific basis for conservation efforts. However, such rigorous assessments are methodologically complex and logistically difficult, and consequently many commonly used ungulate population survey methods do not address key problems. As a result of such deficiencies, key parameters related to population distribution, abundance, habitat ecology and management of tropical forest ungulates remain poorly understood. This book addresses this critical knowledge gap by examining how population abundance patterns in five threatened species of large ungulates vary across space in the tropical forests of the Nagarahole-Bandipur reserves in southwestern India. It also explains the development and application of an innovative methodology – spatially explicit line transect sampling – based on an advanced hierarchical modelling under the Bayesian inferential framework, which overcomes common methodological deficiencies in current ungulate surveys. The methods and results presented provide valuable reference material for researchers and professionals involved in studying and managing wild ungulate populations around the globe. .
    Type of Medium: Online Resource
    Pages: XXVII, 195 p. 46 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811569340
    DDC: 333.9516
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Human physiology. ; Reproduction. ; Physiology. ; Anatomy. ; Cytology. ; Human Physiology. ; Reproductive Physiology. ; Anatomy. ; Cell Biology.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Origin and development of the breast -- Chapter 3: Structure of the lactating breast -- Chapter 4: Breast function during the initial period of lactation (lactogenesis I and II) -- Chapter 5: The period of established lactation (lactogenesis III).
    Abstract: This comprehensive Monograph examines all peripheral and central mechanisms of regulating the secretion of milk from the lactating breast. The author reviews the complete female breast development, starting with the early childhood, up to pregnancy and lactation. Structural and ultrastructural data on the alveolar-ductal system, together with details of breast innervation, are used to investigate the physiological process of lactation. Readers will appreciate the special focus on reflexes, both in the child and the mother, that help to regulate maternal milk production and secretion. Following this, the author sheds a light on the composition and dynamics of milk components during the different periods of lactation. The final section of this volume focusses on practical aspects of modern breastfeeding, like the use of breast pumps or galactogogues, to influence the productivity of milk production. These fundamental principles and structural details will be particularly useful for physiologists and clinicians working in gynecology and pediatrics.
    Type of Medium: Online Resource
    Pages: VIII, 254 p. 87 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030663643
    DDC: 612
    Language: English
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  • 5
    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    DDC: 615
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Proteins . ; Biotechnology. ; Enzymology. ; Bioorganic chemistry. ; Protein Biochemistry. ; Chemical Bioengineering. ; Enzymology. ; Bioorganic Chemistry.
    Description / Table of Contents: Preface -- Chapter 1: Introduction -- Chapter 2: Enzyme Cascade Design – Retrosynthesis Approach -- Chapter 3 : Multi-Enzymatic Cascades in vitro -- Chapter 4: Multi-Enzymatic Cascades in vivo -- Chapter 5: Chemo-Enzymatic Cascades -- Chapter 6: Enzyme Cascade Kinetic Modelling -- Chapter 7: Enzyme Cascade Reaction Engineering -- Chapter 8: Enzyme Cascade Process Design and Modelling -- Chapter 9: Enzyme Cascade Reaction Monitoring And Control -- Chapter 10: Cascade reactions in non-conventional media -- Chapter 11: Perspectives.
    Abstract: This book provides a comprehensive overview of the recent developments achieved in the field of chemo/enzymatic cascades with topics spanning from design (in vitro and in vivo) to kinetic- and process modelling as well as process control. Opportunities and challenges of building multi-step chemo/enzymatic reactions are discussed, whereby the latter are critically assessed in each chapter and methods to ease the implementation are explored. Both, multi-enzymatic cascades and chemo-enzymatic cascades are presented with the motivation of combining the strengths of these two worlds (e.g. selectivity, activity and robustness) not neglecting the obstacles and challenges of such endeavour. Furthermore, the use of non-conventional media for catalytic cascade reactions, recent achievements and potential for future developments in a technical environment are addressed.
    Type of Medium: Online Resource
    Pages: VII, 181 p. 103 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030657185
    DDC: 572.6
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Radiology. ; Spectrum analysis. ; Pharmaceutical chemistry. ; Nutrition   . ; Biomedical Research. ; Radiology. ; Spectroscopy. ; Pharmaceutics. ; Nutrition.
    Description / Table of Contents: Ch 1: Electron Spin Resonance- An Introdcution -- Ch 2: ESR – Applications in Healthcare and Pharmaceutical Science -- Ch 3: ESR Applications in Paleontology and Geochronology -- Ch 4: ESR Applications in Food Science.
    Abstract: This book introduces the audience with basic theoretical and experimental aspects of Electron Spin Resonance (ESR) Spectroscopy. It further talks about ESR spectroscopy applications in Healthcare & Pharmaceutical Science, Paleontology & Geochronology and Food Science. Mathematical details have been kept to a necessary minimum and emphasis is given to highlight the applications of the technique.
    Type of Medium: Online Resource
    Pages: X, 72 p. 32 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030641986
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    DDC: 610.72
    Language: English
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  • 8
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Bioinformatics. ; Immunology. ; Cancer Biology. ; Computational and Systems Biology. ; Immunology.
    Description / Table of Contents: 1. Introduction: Introduction of lipids, lipid metabolism and tumor immunity -- 2. ipid metabolism and lipidomics -- 3. Applications of lipidomics in tumour immunity.-4. Overview: Lipid metabolism in tumour microenvironment -- 5. Lipid metabolism in cancer cells -- 6. Lipid metabolism in tumour-associated NK -- 7. Lipid metabolism in tumour-associated macrophages -- 8. Lipid metabolism in tumour-associated MDSCs -- 9. Lipid metabolism in tumour-associated fibroblasts -- 10. Lipid metabolism in tumour-associated B cells -- 11. Lipid metabolism in tumour-infiltrating T cells -- 12. Lipid metabolism and angiogenesis -- 13. Lipid metabolism and tumor antigen-presenting -- 14. Lipid metabolism and immune checkpoints.
    Abstract: This book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity. Recently, lipid metabolism is an emerging research direction and contributes to cell survival and biofunctions in tumor microenvironment, which is of great interest and significance to be elucidated. This book provides the doctors, researchers, and scientists with a cutting-edge overview of the lipid metabolism and its role in tumor immunity. It also yields benefits for pharmaceutical companies regarding drug discovery. .
    Type of Medium: Online Resource
    Pages: XI, 211 p. 24 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813367852
    Series Statement: Advances in Experimental Medicine and Biology, 1316
    DDC: 571.978
    Language: English
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  • 9
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Human physiology. ; Radiology. ; Diseases. ; Bioinformatics. ; Immunology. ; Human Physiology. ; Radiology. ; Diseases. ; Computational and Systems Biology. ; Immunology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. The Economics of Obesity-A Public Policy Perspective -- Chapter 3. Obesity and skin problems -- Chapter 4. Obesity and endometriosis -- Chapter 5. Hypogonadism -- Chapter 6. Effect of obesity in cardiovascular system -- Chapter 7. Impact of obesity on vaccination -- Chapter 8. Obesity-linked diseases (Comorbidities) -- Chapter 9. Imaging as a tool for measuring body fat -- Chapter 10. Extrapolation from clinical trial to practice: current pharmacotherapy on obesity -- Chapter 11. Nanotechnology in the context of obesity -- Chapter 12. Computational approach in drug development for obesity.
    Abstract: This book summarizes the effects of obesity on health and its correlation with a wide range of debilitating and life-threatening conditions in humans. It discusses the possible pathological mechanisms that are involved in the development of obesity and highlights obesity-associated molecular mechanisms that contribute to reproductive dysfunctions in men and women. The book provides mechanistic insights on the role of obesity in cardiovascular and respiratory disorders, and examines the role of the complementary molecular mechanism of the gut microbiota in the development of obesity. It also reviews the interaction between the metabolic system and immune cells in the pathogenesis of obesity-associated diseases. Lastly, it assesses the latest advances in nanomedicine as an emerging strategy for the treatment of obesity.
    Type of Medium: Online Resource
    Pages: XVI, 181 p. 13 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813364080
    DDC: 612
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biochemistry. ; Renewable energy sources. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Sustainability. ; Biochemistry. ; Renewable Energy. ; Environmental Engineering/Biotechnology. ; Sustainability.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Fractionation strategies -- Chapter 3. Biochemical conversion of cellulose -- Chapter 4. Biochemical conversion of hemicellulose -- Chapter 5. Biochemical conversion of lignin -- Chapter 6. Thermochemical conversion of cellulose and hemicellulose -- Chapter 7. Thermochemical conversion of lignin -- Chapter 8. Material application of lignin -- Chapter 9. TEA for evaluating biorefinery strategies.
    Abstract: This book focuses on the technologies developed for the conversion of all three biomass components, i.e. cellulose, hemicellulose and lignin, and their constituents, to fuels and high-value products. Both biochemical and thermochemical approaches are reviewed. Additionally, the developed technologies are described in detail and their potential applications as well as their commercial status are discussed. The early attempts to produce fuel ethanol from lignocellulosic biomass feedstock focused solely on the biological conversion of cellulose because the only organism that had been used successfully for commercial production of ethanol, i.e. Saccharomyces cerevisiae, could only ferment glucose, which was obtained from the hydrolysis of cellulose. Hemicellulose and lignin were considered as wastes in these processes and were normally removed in pretreatment processes to enhance enzymatic hydrolysis of the remaining cellulose. However, this approach was not economically feasible and as a result, the biorefinery concept was developed. In a biorefinery, in addition to ethanol, various higher-value products are produced from hemicellulose and lignin, which were previously not considered. Consequently, technologies were developed for the fractionation of biomass and conversion of hemicellulose and lignin to fuels and high-value products to improve the economic feasibility. Written and edited by a team of investigators with many years of experience in biomass processing research and development, this book is an informative resource for postgraduate students and researchers interested in biorefinery and biofuel technologies both in academia- and commercial laboratories.
    Type of Medium: Online Resource
    Pages: IX, 245 p. 43 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031058356
    DDC: 572
    Language: English
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  • 11
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Botanical chemistry. ; Plant physiology. ; Agriculture. ; Plant Science. ; Plant Biochemistry. ; Plant Physiology. ; Agriculture.
    Description / Table of Contents: How the three organ-produced signals: auxin, cytokinin and gibberellin, induce and regulate wood formation and adaptation -- Role of plant growth regulators in the plant-environment interaction and epigenetic regulation of auxin -- The role of auxin and cytokinin signaling components in de novo shoot organogenesis -- Mechanism of crosstalk between cytokinin and gibberellin -- In vitro responses of some Mediterranean fruit crops to auxin, cytokinin and gibberellin treatments -- Integrative approach of the root architecture by interaction between auxin and nutrients -- Insights into Biosynthesis and Signaling of Cytokinins during Plant Growth, Development and Stress Tolerance -- Cytokinin signaling in plants under salt stress -- Auxin and Cytokinin Signaling in Plant Stress Response -- Gibberellins' cross talk and signal transduction in plant stress response -- Crosstalk between Salicylic acid and Auxins, Cytokinins and Gibberellins under biotic stress -- Understanding the crosstalk between chromatin remodeling mechanism and phytohormones signaling for maintenance of plant developmental plasticity: an insight -- Phytohormone-mediated regulation of sprouting in tuber and storage root crops -- Role of phytohormones in plant-microbial interaction -- Iron toxicity tolerance in rice: roles of auxins and gibberellins -- New auxin and cytokinin related compounds based on synthetic low molecular weight heterocycles.
    Abstract: Plant hormones have pivotal roles in the regulation of plant growth, development, and reproduction. Their signaling pathways are interconnected in a complex network, which provides plants with an enormous regulatory potential to rapidly adapt to their environment and to utilize their limited resources for growth and survival in a cost-efficient manner. Auxin is a hormone molecule whose activity levels are most important for its regulatory roles during plant cell, organ, and tissue development. Therefore, the precise regulation of auxin levels is an essential mechanism to fine-tune the activity of this powerful hormone during plant growth and development. Likewise, cytokinins exhibit a wide range of physiological functions, including regulation of shoot and root apical meristems, stimulation of branching, vascular development, chloroplast differentiation, stabilization of the structure and function of the photosynthetic machinery, delay of senescence, stomata opening, and elevation of the sink strength and nutritional signaling. Moreover, gibberellins also regulate many aspects of plant growth and development including seed germination, stem elongation, leaf expansion, and flower and fruit development. The broad implication of gibberellins in plant development is strictly associated with tight regulation of their metabolism by multiple environmental and endogenous factors, ranging from light and temperature to other hormones including feedback control. Understanding the significant roles of these phytohormones in plant biology, the current subject has attracted the attention of scientists from across the globe. This comprehensive volume “Auxins, Cytokinins and Gibberellins Signaling in Plants” highlights the various prospects involved in the current scenario. The book comprises the chapters from diverse areas dealing with biotechnology, molecular biology, proteomics, genomics, metabolomics, etc.
    Type of Medium: Online Resource
    Pages: IX, 377 p. 63 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031054273
    Series Statement: Signaling and Communication in Plants,
    DDC: 580
    Language: English
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  • 12
    Keywords: Pharmacology. ; Medical genetics. ; Pathology. ; Pharmacology. ; Clinical Genetics. ; Pathology.
    Description / Table of Contents: Inflammatory skin disease models in vitro and in animals – predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development “Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
    Abstract: This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
    Type of Medium: Online Resource
    Pages: VIII, 323 p. 70 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030700638
    Series Statement: Handbook of Experimental Pharmacology, 265
    DDC: 615
    Language: English
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  • 13
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant anatomy. ; Plant physiology. ; Landscape architecture. ; Plant diseases. ; Agriculture. ; Plant Anatomy and Morphology. ; Plant Physiology. ; Landscape Architecture. ; Plant Pathology. ; Agriculture.
    Description / Table of Contents: Preface -- Introduction -- 1. Nomenclature -- 2. Lycopods And Monilophytes -- 3. Gymnosperms -- 4. Angiosperms: Flowering Plants -- Index.
    Abstract: Horticulture has remained far behind in understanding of botanical principles. Recent phylogenetic (DNA-based) reorganization of higher plants has revolutionized taxonomic treatments of all biological entities, even when morphology does not completely agree with their organization. This book is an example of applying principals of botanical phylogenetic taxonomy to assemble genera, species, and cultivars of 200 vascular plant families of ferns, gymnosperms, and angiosperms that are cultivated for enhancement of human living space; homes, gardens, and parks. The emphases are on cultivated species but examples of some plants are often shown in the wild and in landscapes. In providing descriptions, it is assumed that students and other interested individuals have no background in general botany (plant characteristics), or nomenclature. Fundamental features of all plant groups discussed are fully illustrated by original watercolor drawings or photographs. Discussion of the families is grounded on recent botanical phylogenetic treatments, which is based on common ancestry (monophyly). Of course, phylogenetic taxonomy is not a new concept, and was originally based on morphological characteristics; it is the DNA-based phylogeny that has revolutionized modern biological classifications. In practical terms, this book represents the horticultural treatment that corresponds to phylogenetic-based botanical taxonomy, to which is added cultigens and cultivated genera and species. Hence, the harmony between horticultural and botanical taxonomy. This book covers phylogenetic-based taxonomy of Ferns, Gymnosperms, and Angiosperms (Monocots). A companion volume covers Angiosperms (Eudicots).
    Type of Medium: Online Resource
    Pages: XXV, 700 p. 551 illus., 549 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031115615
    DDC: 571.32
    Language: English
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  • 14
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical policy. ; Quality of life. ; Biomedical Research. ; Health Policy. ; Quality of Life Research.
    Description / Table of Contents: Foreword: Challenges & Opportunities for LGBT Populations and Cancer in Global Oncology -- Introduction -- Africa -- A Double Dose Of Stigma – Being Gay And Living With Cancer In Kenya -- Sexual Orientation, Gender Identity and Cancer in South Africa -- Americas -- Making the Situation of TLGBI People around Cancer visible: Observations from the Andean Region -- Cancer Care Challenges for the LGBT Population in Brazil -- Cancer and the SGM Population in Canada and the United States of America -- South-East Asia -- The South-East Asia Region: Societal Conditions for LGBT Health and Cancer Research -- Europe -- Foreword: The Eurocentralasian Lesbian* Community Perspective on Cancer and LBQ women: Advocating for more Research and Activism Collaboration -- LGBT+ and Cancer in the WHO European Region: Current Situation in 12 Eastern European and Central Asian Countries -- Sexual and Gender Minorities and Cancer in Germany: The Striking Absence of Understanding their Cancer-related Needs -- LGBT Populations and Cancer in the UK -- Eastern Mediterranean -- LGBT Populations and Cancer in the Eastern Mediterranean Region: Insights and Challenges with a Focus on Lebanon -- Western Pacific -- LGBT Populations and Cancer in Australia and New Zealand -- Challenges in Cancer Control Confronting the LGBT Population in China: Health Risks, Unique Barriers, and Unmet Needs -- What Have We Learned about Cancer and the Global LGBT Community? -- Index.
    Abstract: Lesbian, Gay, Bisexual, and Transgender (LGBT) also known as sexual and gender minority (SGM) populations have been the focus of global attention. Most importantly, LGBT populations have been addressed in the context of human rights in multiple reports and other activities by the United Nations and other international organizations. There is great variation among countries in the recognition of LGBT individuals’ human rights. A global focus on LGBT populations’ health is still limited, with the notable exception of HIV research. This book on LGBT populations and cancer in the global context is, therefore, an important step in that it will broaden the focus on LGBT populations’ health. Globally, cancer is the second leading cause of death. Cancer morbidity and mortality are increasing disproportionately among populations in lower-income countries. A review conducted by the World Health Organization (WHO) found that of the 82% of member states (158) countries, only 35% of the national cancer control plans addresses vulnerable population, including LGBT populations. These findings reflect an increasing awareness about equity when addressing cancer prevention and control, including LGBT populations. This book addresses LGBT populations’ cancer burden across countries that range from high- to low-income countries to support efforts in diverse countries that are working towards reducing LGBT populations’ cancer burden. It documents place-specific challenges that impede progress towards reducing the LGBT cancer burden as well as critically assesses the variation in cancer control efforts that target LGBT populations and cancer to support progress at a global scale. This book includes six sections that cover the six WHO regions, with each chapter written by an author from the specific region s/he is covering. Each chapter makes use of a template that contextualizes the region, local data collection/availability, risk factors, cancer prevention, detection, diagnosis, treatment, and survivorship.
    Type of Medium: Online Resource
    Pages: X, 335 p. 3 illus., 2 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031065859
    DDC: 610.72
    Language: English
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  • 15
    Online Resource
    Online Resource
    Dordrecht :Springer Netherlands :
    Keywords: Neurology . ; Internal medicine. ; Psychiatry. ; Neurology. ; Internal Medicine. ; Psychiatry.
    Description / Table of Contents: Chapter 1. Evolving approaches to identifying genetic risk variants for sleep disorders -- Chapter 2. Neurobiology of sleep-wake control -- Chapter 3. Prostaglandins, adenosine and histaminergic system in the regulation of sleep and wakefulness -- Chapter 4.Sleep and Neuronal Plasticity -- Chapter 5. Epidemiology of Insufficient Sleep -- Chapter 6.Social Factors in Insufficient Sleep -- Chapter 7. Sleep Loss and the Unfolded Protein Response -- Chapter 8. Biological and genetic mechanisms of sleepiness in Obstructive Sleep Apnea and Cardiovascular Disease -- Chapter 9.Diaphragm EMG recording and its application in sleep medicine -- Chapter 10. Chronic Intermittent Hypoxia in Patients with OSA -- Chapter 11.Neural injury in models of intermittent hypoxia -- Chapter 12. Narcolepsy and Orexin/hypocretin -- Chapter 13.Circadian Rhythm Sleep-Wake Disorders: Mechanisms and Treatment.
    Abstract: The aim of this book is to provide health care professionals with an overview of the main aspects of recent advances in sleep medicine, with an emphasis on advancing basic science into clinical medicine. It is divided into three main parts. The first part is to cover the basic sleep mechanisms which includes genetics in sleep, and neural and humoral regulation of sleep and wakefulness. The second part focuses on the epidemiology of sleep, and the final part consists of the pathophysiological mechanisms of snoring and sleep apnea and other common sleep disorders as well as the consequences. The content of this book is written by experts and sleep specialists from all over the world and this book aims to optimize the health of individuals by “translating” bench side findings into clinical practice.
    Type of Medium: Online Resource
    Pages: VI, 282 p. 43 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789402421682
    Series Statement: Translational Medicine Research,
    DDC: 616.8
    Language: English
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  • 16
    Keywords: Agriculture. ; Nutrition   . ; Animal biotechnology. ; Agriculture. ; Nutrition. ; Animal Biotechnology.
    Description / Table of Contents: Preface -- 1. Impact of sex steroids on the stress response and welfare in female farm ruminants (Aline Freitas-de-Melo and Rodolfo Ungerfeld) -- 2. Insights from proteomics in kidney disease diagnosis and various in vitro and in vivo experimental models (Vikram Patial, Garima Dadhich, and Rajiv Kumar) -- 3. Generation of gene edited pigs (S. Navarro-Serna, C. Piñeiro-Silva, R Romar, J. Parrington, and J Gadea) -- 4. Dietary anti-nutritional factors and their roles in livestock nutrition (Salma H. Abu Hafsa, Ayman A. Hassan, Mona M.MY. Elghandour, Alberto Barbabosa-Pliego, Miguel Mellado, and Abdelfattah Z.M. Salem) -- 5. Genetic engineering tools and techniques in livestock production (Ranjitha H.B., Madhu Ramesh, Subhasmita Behera, Dhanesh ValiyaValappil, Suresh H. Basagoudanavar, and Anjum Sherasiya) -- 6. Mineral Ions in Regulation of Hypothalamic-Pituitary-Ovarian Axis (Mustafa Hassan Jan, Harpreet Singh, and Shikha Kapil) -- 7. Molecular Insights of Compromised Female Reproduction in Ruminants under Metabolic and Nutritional Stress (S. Nandi, S. K Tripathi, PSP Gupta, and S. Mondal) -- Index.
    Abstract: This 2nd book provides fundamental concepts and recent applications of biotechnological methods, such as genetic selection, breeding methods and genetic engineering tools. Biotechnology has remarkably improved the productivity of livestock by increasing the reproduction efficiency and decreasing the generation time. The chapters detail the mechanisms of methods for animal reproduction and breeding methods. This book focus on the impact of minerals, steroids metabolic stress, nutritional stress and anti-nutritional factors on the livestock reproduction.
    Type of Medium: Online Resource
    Pages: XV, 255 p. 32 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031074967
    Series Statement: Sustainable Agriculture Reviews, 57
    DDC: 630
    Language: English
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  • 17
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant diseases. ; Agriculture. ; Agricultural genome mapping. ; Agricultural biotechnology. ; Genetics. ; Plant Pathology. ; Agriculture. ; Agricultural Genetics. ; Agricultural Biotechnology. ; Genetics and Genomics.
    Description / Table of Contents: Chapter 1. Newer Genetic Tools, Techniques, Vectors, Promoters and Molecular Markers for Genetic Engineering of Herbivorous Insects -- Chapter 2.Innovative Molecular Approaches for Pest Management -- Chapter 3. Modern Molecular Tools for Insect Diagnostics -- Chapter 4. Artificial Intelligence, Machine Learning and IOT in Pest Management -- Chapter 5. Genetic Tools for Integrated Management of Pests on Honey Bees in the Tropics -- Chapter 6. Genetics and Genomics of Bombyx mori L -- Chapter 7. Enhancing Genetic Efficiency of natural Enemies of Crop Pests -- Chapter 8. Application of Genetic Engineering Technologies to Manage Crop Pests and Diseases in Vietnam -- Chapter 9. Advances, Prospects and Limitations of Genetic Tools for Pest Management Strategies in Sri Lanka -- Chapter 10. Management of Pests Using Genetic Tools in Africa -- Chapter 11. Genetic Tools for the Management of Phytophagous Mites -- Chapter 12. Management of Potato Cyst Nematode (Globodera sp.) Using Biotechnological Approaches -- Chapter 13.Genetic and Molecular Approaches for Management of Potato Viral Diseases and their Vectors. Chapter 14. Genetic variation and Molecular ools for the Management of Brinjal Shoot and Fruit Borer Leucinodes orbonalis Guenée (Lepidoptera: Crambidae) -- Chapter 15. Management of Noctuid Pests using Genetic Tools -- Chapter 16. Genetics and Management of Pest Fruit Flies -- Chapter 17. Molecular Insights into Wing Polymorphism and Migration Patterns of Planthoppers -- Chapter 18. Genetic Engineering Technologies for Management of Crambid Pests -- Chapter 19.Intervention of Modern Genetic Tools for Managing Insect Pests of Fruit Crops -- Chapter 20.Advanced Molecular Diagnostic Tools for Longhorn Beetles -- Chapter 21.Molecular Characterization and Genetic Interventions in an Invasive Spiralling Whitefly Aleurodicus dispersus Russell -- Chapter 22.Recent Genetic Tools for the Management of Stored Product Pests -- Chapter 23.Genetic Tools for Insecticide Resistance Management -- Chapter 24.Genetic improvement of pigeon-pea(Cajanus cajan(L.) Millsp.) and Insect Resistance: strategies and achievements -- Chapter 25.Bruchid Resistance Studies in Blackgram Using Molecular Tools -- Chapter 26.Inducing Insect Resistance in Sesame by Innovative Genetic Manipulation using Mutagens -- Chapter 27.Advances in Insect Resistance Breeding Against Brown Planthopper and Gallmidge in Rice -- Chapter 28.Adoption of Molecular Tools for Combatting the Arthropod Pests.
    Abstract: This contributed volume aims at bringing together all the genetic engineering tools for managing various types of crop pests. The main focus of this book is to explore the application of these tools in pest management. Major pest groups covered in this book are insects, mites and nematodes. The first section covers all major genetic tools and molecular approaches. The second section deals with genetic tools for of beneficial containing three chapters involving honey bees, silkworms and natural enemies. Next section deals with genetic interactions against pests in diverse geographical regions with special focus on Africa, Vietnam and Sri Lanka. Sections four and five addresses diverse aspects as management of pests, genetic behavior, gene expression, plasticity, pathways and interactions and options for mitigation of pests. It serves as a useful resource for professionals in the fields of entomology, agronomy, horticulture, ecology, and environmental sciences, as well as to agricultural producers and plant biotechnologists. .
    Type of Medium: Online Resource
    Pages: XXI, 669 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811902642
    DDC: 571.92
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biology. ; Pharmaceutical chemistry. ; Biochemistry. ; Pharmacology. ; Cytology. ; Biological Sciences. ; Pharmaceutics. ; Biological Chemistry. ; Pharmacology. ; Cell Biology.
    Description / Table of Contents: Bioanalytical Support in Drug Discovery and Development,- Monoclonal Antibodies -- Antibody Drug Conjugates (ADCS) -- Bispecifics and Fusion Proteins -- Emerging Modalities-Part A- (Gene Therapy and Cell Therapy) -- Emerging Modalities Part B (Peptides, Oligonucleotide Based Therapy, Vaccines. .
    Abstract: The book provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. The book focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides. The book starts with an introductory overview of bioanalysis showcasing the integral role it plays in understanding the drug disposition (pharmacokinetics/pharmacodynamics and immunogenicity) and the progression of bioanalytical strategy as the drug progresses through discovery and development stages of the program, taking into consideration the continually evolving regulatory landscape. The book further diversifies into individual biopharmaceutical modalities - monoclonal antibodies, antibody-drug conjugates, bispecifics, Fc-fusion proteins, gene therapies, cell therapies, peptides and oligonucleotides. The individual chapters focus on modality-specific bioanalytical assay strategies, critical reagents, assay formats, analytical platforms, associated bioanalytical challenges and mitigation strategies, industry best practices, and the latest understanding of regulatory guidance as applicable to the fast-growing biopharmaceutical landscape.
    Type of Medium: Online Resource
    Pages: IX, 160 p. 25 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030971939
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 57
    DDC: 570
    Language: English
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  • 19
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Evolution (Biology). ; Biology Philosophy. ; Linguistics. ; Cognitive science. ; Cognitive psychology. ; Evolutionary Biology. ; Philosophy of Biology. ; Linguistics. ; Cognitive Science. ; Cognitive Psychology.
    Description / Table of Contents: Narrative and persuasion -- Two models of communication -- Beyond the social brain -- The narrative brain -- Stories without language.
    Abstract: This book explores the evolutionary and cognitive foundations of human communication, focusing on narrative as its distinctive dimension. Within a framework of continuity with both the communication of our hominin predecessors and that of non-human animals, the book is about a twofold proposal. It includes the idea that (human and animal) communication has an intrinsically persuasive nature along with the hypothesis that humans developed narrative forms of communication in order to enhance their persuasive abilities. In this view, narrative persuasion becomes the feature that distinguishes human communication from animal communication. The study of the transition from animal communication to language addresses both the selective pressures that led communication for persuasive purposes to take a narrative form and the cognitive architectures and expressive systems that enabled our ancestors to cope with the selective pressures of persuasive/narrative-based communication. Language evolution is interdisciplinary, even from the specific perspective of evolutionary pragmatics chosen here. Therefore, this book is intended for researchers working in fields such as cognitive sciences, philosophy, evolutionary biology, cognitive psychology, and primatology. It also represents a valuable resource for advanced students in cognitive sciences, linguistics, and philosophy.
    Type of Medium: Online Resource
    Pages: XIII, 138 p. 3 illus., 2 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031092060
    Series Statement: Interdisciplinary Evolution Research, 7
    DDC: 576.8
    Language: English
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  • 20
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Plant biotechnology. ; Pharmaceutical chemistry. ; Agriculture. ; Proteins . ; Plant Science. ; Plant Biotechnology. ; Pharmaceutics. ; Agriculture. ; Protein Biochemistry.
    Description / Table of Contents: Chapter. 1. Molecular Farming in Plants: Introduction and Applications -- Chapter. 2. Tools and Techniques Used in Plant Molecular Farming -- Chapter. 3. Production of plant natural products in heterologous microbial species -- Chapter. 4. Sustainable Manufacturing of Vaccines, Antibodies, and other Pharmaceuticals -- Chapter. 5. Limitations, Biosafety, ethics, regulatory issues in molecular farming in plants -- Chapter. 6. Conclusion and Perspectives.
    Abstract: Molecular farming is a biotechnological approach that includes the genetic adjustment of agricultural products to create proteins and chemicals for profitable and pharmaceutical purposes. Plant molecular farming describes the manufacture of recombinant proteins and other biologically active product in plants. This approach depends on a genetic transformation of plants that can be accomplished by the methods of stable gene transfer, such as gene transfer to nuclei and chloroplasts, and unstable transfer methods like viral vectors. The requirement for recombinant proteins in terms of quality, quantity, and diversity is increasing exponentially This demand is traditionally met by recombinant protein construction technologies and the engineering of orthodox expression systems based on bacteria or mammalian cell cultures. However, majority of developing countries cannot afford the high costs of medicine derived from such existing methods. Hence, we need to produce not only the new drugs but also the cheaper versions of those already present in the market. Plant molecular farming is considered as a cost-effective technology that has grown and advanced tremendously over the past two decades. This book summarizes the advances and challenges of plant molecular farming for all those who are working on or have an interest in this rapidly emerging area of research.
    Type of Medium: Online Resource
    Pages: IX, 77 p. 10 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031127946
    Series Statement: SpringerBriefs in Plant Science,
    DDC: 580
    Language: English
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  • 21
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Food science. ; Chemistry, Organic. ; Food Science. ; Organic Chemistry.
    Description / Table of Contents: Mass and Energy Balances -- Elements of fluid flow -- Elements of Heat transfer -- Elements of Mass transfer -- Reaction kinetics -- Phase and Reaction Equilibrium, and phase transitions -- Thermal processing of foods -- Environmental issues in food engineering -- An engineering view of the fate of food in the Gastrointestinal tract (GIT) -- A selection of engineering methodologies for food product realization -- Index.
    Abstract: As an introductory text book on food engineering principles, this text gives students a firm, quantitative foundation in all aspects of food process and product formulation, packaging, manufacturing processes; engineering aspects of the fate of food in the GI tract; engineering principles of the environmental impact of foods; and principles of process economics and project management. The contents are based on a new definition of Food Engineering which is fit-for-purpose for this day and age: Food Engineering is the work of designing, formulating and manipulating food products which have desired sensory, satiety, health and well-being responses; and developing - across various operational scales - designs for the lowest environmental impact processing, packaging and storage systems capable of realizing the products. Based on this definition, Engineering Principles for Food Process and Product Realization re-defines the core competencies of food engineering, covers the engineering principles needed for food process and product design, and examines the engineering principles relevant to the interactions between food on the one hand, and human health, security and environment on the other – which are the key drivers for the growth of food business. With security, human health and environmental legacy driving business, the engineering paradigm must shift from being farm and preservation focused to becoming consumer focused - which this book aims to achieve. All of these topics are covered at a level that is easy to read and absorb, but with challenging questions and problems which require knowledge integration across topics. This book is uniquely placed to serve as an effective launching pad for undertaking further studies on advanced topics and concepts relating to the design of food processes and products.
    Type of Medium: Online Resource
    Pages: XI, 249 p. 90 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031075704
    Series Statement: Food Engineering Series,
    DDC: 641.3
    Language: English
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  • 22
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neuropharmacology. ; Psychiatry. ; Neurology . ; Neuropharmacology. ; Psychiatry. ; Neurology.
    Description / Table of Contents: Dosing psychedelics and MDMA -- Psychedelic Group Therapy -- Set and Setting: Aesthetic experiences and their contribution to psychedelic therapies -- Psychedelic-Assisted Therapy for Social Adaptability in Autistic Adults -- Foundations for Training Psychedelic Therapists -- Ayahuasca for the Treatment of Depression -- Psilocybin for the Treatment of Depression -- Ketamine for the Treatment of Depression -- The Potential of Psychedelics for End of Life and Palliative Care -- Psychedelic-Assisted Therapy for Addiction and Potential Mechanisms of Action -- Psilocybin for Tobacco Use Disorder -- Psychedelic Drugs as Anti-Inflammatory Agents -- Psilocybin for the Treatment of Obsessive-Compulsive Disorder -- Psilocybin for the Treatment of Headache and Pain Disorders -- Psilocybin for the Treatment of Neurodegenerative Disorders -- Psilocybin for Trauma-Related Disorders.
    Abstract: Psychedelic therapies are gaining traction as potential treatments for a wide range of indications, but the structure and delivery of psychedelic therapies are a sharp departure from more traditional models of psychotherapy and pharmacotherapy for psychiatric and other medical disorders. This may be critical to their success. The current volume provides a comprehensive review of the state of the science of psychedelic therapies, including discussion of models and approaches to psychedelic therapies as well as the current status of safety and efficacy data for mood, substance use, trauma, obsessive-compulsive, neurodevelopmental, neurodegenerative disorders, neurological, and inflammatory disorders.
    Type of Medium: Online Resource
    Pages: VIII, 332 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031121845
    Series Statement: Current Topics in Behavioral Neurosciences, 56
    DDC: 615.78
    Language: English
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  • 23
    Keywords: Neurosciences. ; Biomedical engineering. ; Nanotechnology. ; Biophysics. ; Imaging systems in biology. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Nanoengineering. ; Bioanalysis and Bioimaging. ; Biological Imaging.
    Description / Table of Contents: Part 1 -- Optically-Pumped Magnetometers Compatible with Large Transient Magnetic Fields -- Small animal biomagnetism applications -- Supine OPM-MEG in Multi-layer Cylindrical Shield -- Ambulatory MEG Arrays -- Part 2 -- "Tri-axial helium-4 optically-pumped -- magnetometers for MEG" -- Person-Sized Magnetoencephalography Systems with Optically Pumped Magnetometers -- On-scalp MEG with High-Tc SQUIDs -- "Fiber Coupled OPM in Purely Coil -- Shielded Environment" -- SERF-OPM usability for MEG in two-layer shielded rooms -- Turning OPM-MEG into a Wearable Technology -- Part 3 -- OPM Gradiometer for Magnetorelaxometry -- Unshielded High Bandwidth Magnetorelaxometry of Magnetic Nanoparticles with Optically Pumped Magnetometers -- Adult Magnetocardiography: Principles and Clinical Practice -- Fetal Magnetocardiography with OPMs -- Emerging MR sensors for biomagnetic measurements -- Index.
    Abstract: This contributed volume reviews the latest advances in all the new technologies currently developed for MagnetoEncephaloGraphy (MEG) recordings, as well as sensor technologies and integrated sensor arrays for on-scalp MEG. The book gives an account of the first MEG imaging studies and explores the new field of feasible, experimental paradigms of on-scalp MEG. This is an ideal book for engineers, researchers, and students in the neurosciences interested in MEG imaging. .
    Type of Medium: Online Resource
    Pages: IX, 315 p. 104 illus., 88 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031053634
    DDC: 612.8
    Language: English
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  • 24
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medical genetics. ; Reproductive health. ; Midwifery. ; Immunology. ; Medical Genetics. ; Reproductive Medicine. ; Midwifery. ; Immunology.
    Description / Table of Contents: Chapter 1. Historical Background of Immune Infertility Associated with Anti-Sperm Antibody (ASA) in Women -- Chapter 2. Detection of Anti-Sperm Antibody (ASA) in Women -- Chapter 3. Causes of Immune Infertility in Women with Anti-Sperm Antibody (ASA) -- Chapter 4. Production of Anti-Sperm Antibody (ASA) in Women -- Chapter 5. Non-Assisted Reproductive Technology (ART) Treatments for Infertile Women with Anti-Sperm Antibody (ASA) -- Chapter 6. Assisted Reproductive Technology (ART) as a Treatment for Infertile Women with Anti-Sperm Antibody (ASA) -- Chapter 7. Historical Background of Immune Infertility Associated with Anti-Sperm Antibody (ASA) in Men -- Chapter 8. Detection of Anti-Sperm Antibody (ASA) in Men -- Chapter 9. Causes of Immune Infertility in Men with Anti-Sperm Antibody (ASA) -- Chapter 10. Production of Anti-Sperm Antibody (ASA) in Men -- Chapter 11. Classical Treatments for Infertile Men with Anti-Sperm Antibody (ASA) -- Chapter 12. Assisted Reproductive technology (ART) as A Treatment for Infertile Men with ASA -- Chapter 13. Development of Immunocontraceptives in Famale -- Chapter 14. Development of Immunocontraceptives in Male -- Chapter 15. Wildlife Overpopulation Control -- Chapter 16. Structure of ZP -- Chapter 17. Function of ZP -- Chapter 18. Human ZP -- Chapter 19. ZP in Assisted Reproductive Technology -- Chapter 20. Infertility and Anti-ZP antibody (AZPA) -- Chapter 21. ZP-based Immunocontraceptive vaccine.
    Abstract: This book describes the biology, diagnosis, treatment and the latest research on anti-sperm antibody (ASA) and anti-zona pellucida antibody (AZPA) produced in some infertile patients. It summarizes ASA in both men and women, and presents new research to serve as a guideline for medical treatment, which currently varies considerably. It also discusses the recently identified target antigens of these antibodies, and the latest immunocontraceptive development projects. The book features chapters on AZPA explaining the biological structure and function of the zona pellucida, and describing the abnormality and the antibody. It also provides insights into their evolution, presenting the differences in taxonomy, mammalian physiological functions and the morphologically and immunologically unique human zona pellucida. Gamete Immunology is a valuable resource for researchers, and postdocs who are curious about new research on ASA and AZPA. It offers clinicians and embryologists who are interested in gamete immunology diverse perspectives as well as the basis for new ideas to treat the antibodies and develop contraceptive vaccinogens.
    Type of Medium: Online Resource
    Pages: XV, 279 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811696251
    DDC: 616.042
    Language: English
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  • 25
    Keywords: Microbiology. ; Agriculture. ; Industrial microbiology. ; Microbiology. ; Agriculture. ; Industrial Microbiology.
    Description / Table of Contents: Chapter 1. Plant Growth Promoting Rhizobacteria for Sustainable Agriculture -- Chapter 2. Plant Microbes Interactions and Its Effect on Crop Productivity -- Chapter 3. Rhizobacterial biostimulants: efficacy in enhanced productivity and sustainable agriculture -- Chapter 4. The Role of Arbuscular Mycorrhiza in Sustainable Agriculture -- Chapter 5. Biocontrol Efficacy of Biomass and Secondary Metabolites of P. fluorescens Against Predominant Pest Affecting Agricultural Fields -- Chapter 6. Exopolysaccharide-producing Azotobacter for bioremediation of heavy metal-contaminated soil -- Chapter 7. Utilization of Arbuscular Mycorrhizal Fungi to boom the Efficiency and Product nature of Horticultural Crops -- Chapter 8. Microbial Remediation of Persistent Agrochemicals -- Chapter 9. Microbes Based Pesticides for Insect Pest Control and Their Management -- Chapter 10. In-silico Tools and Approach of CRISPR Application in Agriculture -- Chapter 11. Application of Bioinformatics in the Plant Pathology Research -- Chapter 12. New Age Genomic Measures for Uncovering Plant-Microbiome Interactions: Tools, Pipelines and Guidance Map for Genomic Data Mining -- Chapter 13. Bioinformatics: A Tool for Sustainable Agriculture -- Chapter 14. Recent Advances in Deep Learning CNN Models for Plant Disease Detection.
    Abstract: This book, the second volume of Advances in Agricultural and Industrial Microbiology is the compilation of modern technologies with scientific advancement in promoting plant growth by rhizobacterial biostimulants, endophytic microbes, and arbuscular mycorrhizal fungi. The volume also highlights the critical roles of soil microbes in the biocontrol of plant pathogens/diseases, bioremediation of toxic agrochemicals, and nitrogen fixation. Agricultural sustainability and environmental management strongly depend on microbial communities. Management of soil fertility is the key aspect that is facilitated by soil microbes and their interactions.The book also has a section focuses on the in-silico approaches and techniques involved in agriculture which enhances the readers’ understandings of plant-pathogen interactions, prediction of pathogenicity, improving variety through CRISPER, and its role in the agroindustry. Additionally, the interventions of ICTs (Information and Communication Technologies) have benefited agricultural stakeholders, i.e., farmers to policymakers, in predicting and combating them. The covered topics of the microbial domain and computational tools have high implications for the researchers, students, faculty, and scientists working on these areas.
    Type of Medium: Online Resource
    Pages: IX, 263 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811696824
    DDC: 579
    Language: English
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  • 26
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Post-translational modification. ; Bioinformatics. ; Molecular biology. ; Nervous system Diseases. ; Post-translational Modifications. ; Computational and Systems Biology. ; Molecular Biology. ; Neurological Disorders.
    Description / Table of Contents: Protein extraction and sample preparation methods for shotgun proteomics with central nervous system cells and brain tissue -- Phosphopeptide enrichment techniques: a pivotal step for phosphoproteomic studies -- Post-Translational Modifications during Brain Development -- Aberrant protein glycosylation in brain cancers, with emphasis on glioblastoma -- Post-Translational Modification in Muscular Dystrophies -- Post-translational Modifications in Parkinson’s Disease -- Histone Modifications in Neurological Disorders -- Mitochondrial dysregulation and the influence in neurodegenerative diseases -- PTMs: A missing piece for schizophrenia studies -- Post-Translational Modifications in Brain Diseases: A Future for Biomarkers -- Index.
    Abstract: This new volume, a part of the Proteomics, Metabolomics, Interactomics and Systems Biology series, will explain how proteomic studies of post-translational modifications (PTMs) can be applied to neurodegenerative diseases and relevant studies. The goal of the book is to increase awareness among researchers about how PTMs may be helpful in understanding mechanisms in various neurodegenerative diseases through proteomic studies. This book will serve as a tool for those who want to begin work in the proteomics field and explore how to implement PTMs studies into their work. Chapter authors will describe different PTMs enrichment methods developed by experts in the field so that researchers may learn to apply these methods and techniques to new studies. Divided into three sections, chapters will cover sample preparation, data quality, enrichment techniques, guidelines on how to analyze PTMs, and explain the role of PTMs and different brain diseases. Among those topics includes will be brain cancer, SLA disease, Parkinsons disease, muscular dystrophies, and schizophrenia. This volume will be useful for researchers and students studying brain and neurodegenerative diseases who are interested in delving into work with proteomic studies and PTMs. .
    Type of Medium: Online Resource
    Pages: VIII, 146 p. 13 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031054600
    Series Statement: Proteomics, Metabolomics, Interactomics and Systems Biology, 1382
    DDC: 572.645
    Language: English
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  • 27
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Invertebrates. ; Freshwater ecology. ; Marine ecology. ; Invertebrate Zoology. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Identification Key: Freshwater Invertebrates -- Sponges: Porifera -- Cnidarians: Cnidaria -- Flatworms: Platyhelminthes -- Hairybacks: Gastrotricha; Water Bears: Tardigrada -- Rotifers: Rotifera -- Horsehair Worms: Nematomorpha; Roundworms: Nematoda -- Snails, Limpets and Mussels: Mollusca -- Segmented Worms: Annelida -- Aquatic Spiders and Mites: Chelicerata -- Crustaceans: Crustacea -- Springtails: Collembola -- Mayflies: Ephemeroptera -- Dragonflies and Damselflies: Odonata -- Stoneflies: Plecoptera -- Water Bugs: Heteroptera -- Beetles: Coleoptera -- Sialidae, Osmylidae, Sisyridae -- Caddisflies: Trichoptera -- Moths: Lepidoptera -- True Flies: Diptera -- Moss Animals: Bryozoa.
    Abstract: This up-to-date guidebook on freshwater invertebrates of the central European region is a richly illustrated work, providing an excellent source of systematic information on freshwater macroinvertebrates. Numerous colour photos and additional vector graphic figures allow readers to identify specific species at a higher taxonomic level (family). The book is supplemented by video sequences. Freshwater Invertebrates in Central Europe – A Field Guide is a must-have for all those interested in the freshwater animals of central Europe such as animal scientists and ecologists, as well as students attending classes on freshwater invertebrate.
    Type of Medium: Online Resource
    Pages: X, 527 p. 525 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030953232
    DDC: 592
    Language: English
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  • 28
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Gynecology . ; Human physiology. ; Immunology. ; Biomedical Research. ; Gynecology. ; Human Physiology.
    Description / Table of Contents: Part I -- Chapter 1: Introduction -- Chapter 2: Recurrent Pregnancy Loss and Recurrent Implantation Failure -- Chapter 3: Immune System -- Chapter 4: Immunology of Pregnancy (Reproductive Immunology) -- Chapter 5: Diagnosis of Alloimmune factor -- Part II -- Chapter 6: Introduction -- Chapter 7: History of LIT -- Chapter 8: Mechanism of Action of LIT -- Chapter 9: Procedure of LIT -- Chapter 10: Safety of LIT -- Chapter 11: Controversies about LIT – REMIS Study -- Chapter 12: Cochrane Reviews & LIT -- Chapter 13: Recent Meta-analyses & LIT -- Chapter 14: Review of International studies of LIT -- Chapter 15: Case Studies -- Chapter 16: Future of LIT.
    Abstract: Recurrent Miscarriages (RM) & Implantation Failure (IF) have remained an enigma to clinicians and researchers. Even after ruling out all possible causative factors, 50-60% cases still remain “Unexplained’. A majority of these so called “Unexplained” cases are now found to have immunological basis. This book is going into the Immunological aspects of these clinical dilemmas, demystifying the role of Immunology and Immunotherapy in RM and IF. The authors have been working in the field of Reproductive Immunology and Immunotherapy for the last 25 years and they have come out with this book combining the international studies with their own experience. The purpose of writing this book is to provide a comprehensive treatise about Immunotherapy, so that it can become an acceptable modality of treatment in cases where it is needed and is effective. The book discusses the basics in Reproductive Immunology. The immunological changes occurring during pregnancy, the role of Cell mediated Immunity (T cells), Humoral Immunity including cytokines is explained. The normal immunological mechanisms protecting the embryo are highlighted and how these mechanisms are disturbed leading to RM and IF, is also explained. The first and the most discussed method of Immunotherapy is Lymphocyte Immunization Therapy (LIT). The book has given a complete overview of LIT, describing how it created euphoria when it was first introduced, how it gradually went into disrepute and how it is now making a comeback. As the authors have personal experience of LIT, the book gives a detailed and complete information about this active form of immunotherapy. The book has a special section on case studies where the authors have given some clinical case reports (including some of their own), who were treated for immunological factor in RM/IF and were treated with Immunotherapy. These cases can be a useful guide to the readers. The book will be useful not only for undergraduate and postgraduate students but also for clinicians in their practice and for researchers for review of developments in the field.
    Type of Medium: Online Resource
    Pages: XVIII, 147 p. 33 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811929601
    DDC: 571.96
    Language: English
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  • 29
    Keywords: Evolution (Biology). ; Environment. ; History. ; Conservation biology. ; Ecology . ; Ethics. ; Environmental sciences Social aspects. ; Evolutionary Biology. ; Environmental Sciences. ; History. ; Conservation Biology. ; Moral Philosophy and Applied Ethics. ; Environmental Social Sciences.
    Description / Table of Contents: Part I. Biology and Culture -- Chapter 1. Speciesism in Biology and Culture: How Human Exceptionalism is Pushing Planetary Boundaries -- Chapter 2. Race and Human Genomic Variation -- Chapter 3. Science Without Species: Doing Science With Tree-Thinking -- Part II. Culture and History -- Chapter 4. The Colonization of Islands as Microcosms for Human Impacts on an Interplanetary Scale -- Chapter 5. Species, God, and Dominion -- Chapter 6. Symbols and How We Came to be Human -- Part III. Conservation and Law -- Chapter 7. Law and Nature: Human, Nonhuman, and Ecosystem Rights -- Chapter 8. A Phylogenetic Approach to Conservation: Biodiversity and Ecosystem Functioning for a Changing Globe -- Part IV. Sustainability and the Future -- Chapter 9. Energy and Society: Toward a Sustainable Future.
    Abstract: This open access book explores a wide-ranging discussion about the sociopolitical, cultural, and scientific ramifications of speciesism and world views that derive from it. In this light, it integrates subjects across the natural sciences, social sciences, and humanities. The 21st-century western world is anthropocentric to an extreme; we adopt unreasonably self-centered and self-serving ideas and lifestyles. Americans consume more energy resources per person than most other nations on Earth and have little concept of how human ecology and population biology interface with global sustainability. We draw upon religion, popular culture, politics, and technology to justify our views and actions, yet remain self-centered because our considerations rarely extend beyond our immediate interests. Stepping upward on the hierarchy from “racism,” “speciesism” likewise refers to the view that unique natural kinds (species) exist and are an important structural element of biodiversity. This ideology manifests in the cultural idea that humans are distinct from and intrinsically superior to other forms of life. It further carries a plurality of implications for how we perceive ourselves in relation to nature, how we view Judeo-Christian religions and their tenets, how we respond to scientific data about social problems such as climate change, and how willing we are to change our actions in the face of evidence. .
    Type of Medium: Online Resource
    Pages: XVI, 203 p. 28 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030990312
    DDC: 576.8
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Food science. ; Nutrition   . ; Bioinformatics. ; Biotechnology. ; Food Science. ; Nutrition. ; Computational and Systems Biology. ; Biotechnology.
    Description / Table of Contents: Soybean (Glycine max) -- Rapeseed/Canola (Brassica napus) -- Cottonseed (Gossypium hirsutum),- Ground nut (Arachis hypogaea) -- Sunflower (Helianthus annuus) seed -- Palm /Palm kernel (Elaeis guineensis) -- Coconut (Cocos nucifera),- Mustard (Brassica nigra) seed,- Olive (Olea europaea),- Flaxseed (Linum usitatissimum), - Chia seed (Salvia hispanica),- Sesame (Sesamum indicum) seed -- Nigella (Nigella sativa) seed,- Borage (Borago officinalis) seed,- Hempseed (Cannabis sativa),- Rice (Oryza sativa) bran,- Safflower (Carthamus tinctorius) -- Camelina (Camelina sativa) seed,- Pumpkin (Cucurbita pepo) seed,- Cumin (Cuminum cyminum) seed.
    Abstract: Oilseeds offer a plethora of opportunities for the food and feed industry, thanks to their high oil and protein content . Their phytonutrients and functional components have attracted the interest of researchers, leading to the development of functional foods. This book gathers the latest scientific information on the nutrients, phytonutrients and health benefits as well as the adverse effects of consuming various conventional and non-conventional oilseeds. In addition, each chapter includes a section comprehensively explaining the use of oilseeds in functional bakery, dairy, and other food products. Given its scope, the book is a valuable resource for students, researchers, nutritionists, food scientists and technologists, and for anyone involved in product development based on oilseed and its components.
    Type of Medium: Online Resource
    Pages: IX, 517 p. 42 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811541940
    DDC: 641.3
    Language: English
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  • 31
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Animal migration. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Biodiversity. ; Animal Migration.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. European pearl mussel: background information and literature review -- Chapter 3. Materials and methods -- Chapter 4. Results -- Chapter 5. Discussion -- Chapter 6. Conclusions.
    Abstract: The monograph focuses on the European freshwater pearl mussel Margaritifera margaritifera, which is an endangered bivalve species. Most of its populations in the Russian section of the Baltic Sea basin had never been studied, although they were known in the past to the pearl fishers. “Rediscovery” included search for the previously unknown populations, revealing the facts of population extinctions, analysis of negative impacts, elaboration of conservation measures, and revealing of regularities in distribution. Patterns of land use and river management were analyzed. The procedure of “rediscovery” was applied for other animal species of Northwest Russia, which are threatened on a global scale – thick-shelled mussel, Unio crassus; curlew Numenius arquata; black-tailed godwit, Limosa limosa; Northern Lapwing, Vanellus vanellus; European mink, Mustela lutreola; pond bat, Myotis dasycneme; Atlantic sturgeon, Acipenser sturio; and broad-clawed crayfish, Astacus astacus. The methods and principles of conservation studies were discussed. The obtained data were analyzed with respect to current global change of biosphere. The book will appeal to specialists dealing with conservation studies and activities such as red lists, river protection, and conservation of endangered species. Moreover, a part of the book represents an interest for biogerontology as it presents discredit of the popular concept on “negligible senescence.” The data on distribution of some animals in Russia will be interesting in terms of zoology and biogeography, as they are not yet sufficiently represented in the international editions. The book can be used as supplemental reading for courses in biological invasions, ecology and conservation, and biodiversity. The work also contains chapters on global processes (deforestation, desertification, river degradation) and can therefore also be used for general courses in environmental sciences.
    Type of Medium: Online Resource
    Pages: XI, 246 p. 88 illus., 87 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030662554
    DDC: 577.6
    Language: English
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  • 32
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant biotechnology. ; Plant genetics. ; Agriculture. ; Plant Biotechnology. ; Plant Genetics. ; Agriculture.
    Description / Table of Contents: Economic/Academic importance -- Background of the sequencing initiatives -- Molecular mapping and cloning of genes and QTLs -- Physical mapping of the genome -- Whole genome sequencing and assembling -- Structure and composition of centromere in Brassica genome -- Genome annotation -- Gene loss -- Alternative splicing -- Gene conversion -- Gene family differentiation in Brassica species -- Glucosinates -- R genes variations after triplication -- Structural & functional genomic resources developed -- Impact on plant breeding and crop improvement -- Data bases -- Future prospects.
    Abstract: This book presents comprehensive information on genetics, genomics and breeding in Brassica oleracea, an agriculturally important species that includes popular vegetable crops such as cabbage, cauliflower, broccoli, Brussels sprouts, kale, collard greens, savoy, kohlrabi, and gai lan. The content spans whole genome sequencing, assembly and gene annotation for this global vegetable species, along with molecular mapping and cloning of genes, physical genome mapping and analyses of the structure and composition of centromeres in the B. oleracea genome. The book also elaborates on asymmetrical genome evolution and transposable elements in the B. oleracea describes gene family differentiation in comparison to other Brassica species and structural and functional genomic resources and data bases developed for B. oleracea. Useful discussions on the impact of genome sequencing on genetic improvement in the species are also included.
    Type of Medium: Online Resource
    Pages: XXIV, 145 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030310059
    Series Statement: Compendium of Plant Genomes,
    DDC: 631.52
    Language: English
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  • 33
    Keywords: Microbiology. ; Renewable energy sources. ; Microbiology. ; Renewable Energy.
    Description / Table of Contents: Chapter 1. Advancements in Biofuel Production -- Chapter 2. Bionenergy: Sustainable Renewable Energy -- Chapter 3. Biofuel from Microalgae -- Chapter 4. Waste to bioenergy: Recent Technologies -- Chapter 5. Bioenergy from Agricultural Wastes -- Chapter 6. Bio-Processing: Biomass to Commercial Alcohol -- Chapter 7. Hydrogen Production by Utilizing Bio-Processing Techniques -- Chapter 8. Bacterial Hydrogen Production: Prospects and Challenges -- Chapter 9. Bioethanol Production from Biodiesel Derived Glycerol – A Case Study -- Chapter 10. Advancement on biomass classification, analytical methods for characterization and its economic importance.
    Abstract: This volume is fourth part of the five-part set on bioenergy research. This volume covers biomass to bioenergy production concept. The book is focused on the possible and versatile biomass options available for the generation of bioenergy. Additionally, the book also explores different types of biomass for bioenergy generation at a commercial level. Further, the book elaborates on different kind of cellulose and sugar rich waste which can also be utilized for bioenergy production. It covers other relevant issues such as recent technological advancement in biomass to bioenergy conversion, waste management in the context of biomass to biofuels production technologies, green methods of energy production, alternates of fossil fuels in the near future. It also explores biomass waste valorization, utilizing microbial processes in bioenergy production. This is a useful reading material for students, researchers, industry and policy experts. Other four volumes of this set explore basic concepts, latest progress, commercial opportunities and integrated solution for bioenergy concerns. .
    Type of Medium: Online Resource
    Pages: XI, 272 p. 35 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811618628
    Series Statement: Clean Energy Production Technologies,
    DDC: 579
    Language: English
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  • 34
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Hematology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Hematology.
    Description / Table of Contents: Live Donors of Tissue -- Deceased Tissue Donors -- Banking and Use of Umbilical Cord Blood -- Ocular tissue banking -- Banking of Heart Valves -- Cryopreservation and Banking of Haematopoietic Progenitor Cells -- Storage, Processing and Preservation -- Cryopreservation in tissue banking -- Sterilisation by Irradiation -- Screening the tissue donor for infectious agents -- Contamination in the Tissue Way -- Establishing a Quality System in a Tissue Establishment -- IT System requirements for Tissue and Cell Banking -- Ethical and Regulatory Aspects of Cell and Tissue Banking -- Human embryonic stem cell banking for clinical applications – 20 years from their isolation.
    Abstract: It has been 10 years since the first edition of ‘Essentials of Tissue Banking’ has been published. There is still relatively little published on the technical and scientific principles on routine tissue and cell banking based on scientific principles. The 1st edition was very successful and, after a 10 year gap, there is a need of an update and an expansion of the book’s remit. The format of the book follows that of the previous edition- split into 5 sections. Management of donors and the banking of common tissues and cells; Principles of storage and processing of tissues and cells; Ensuring the safety of the products by testing the donor, the tissues and the environment, supported by a quality system and an IT infrastructure- all working within the constraints of current regulatory and ethical environments. This edition however provides a significant update. Many the chapters have been completely rewritten by different experts. Like the 1st edition, they were given a free hand in the way they wrote their chapter, with a guideline that they had to be concise, clear and up to date. The authors were also asked to provide the scientific and technical basis that provides the rationale of the processes they describe. Also, the scope of the book has been somewhat extended. In view of the fact that many cellular therapies are now routinely practiced, 2 new chapters have been added: one on the banking of haematopoietic stem cells and one on human embryonic stem cells. They have been deliberately chosen to illustrate the extreme spectrum of cellular therapies from one of the simplest to one of the most complex. The intention of the book has remained the same: to cover and update banking of current practices in essential tissue and cell banking. It is therefore hoped that by keeping the book as concise and up to date as possible, it will find a place on the shelves of many tissue establishments.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 48 illus., 28 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030716219
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical microbiology. ; Pharmacology. ; Pediatrics. ; Medical Microbiology. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Part 1 General Vaccinology -- 1 Expected and Unexpected Effects of Vaccination -- 2 How Vaccinating People Can Also Protect Others -- 3 Childhood and Adolescent Immunization Programs in Europe -- 4 Vaccine Hesitancy, Acceptance, and Demand -- 5 Adjuvants in Pediatric Vaccines -- 6 Maternal Immunization -- 7 Neonatal Immunization -- Part 2 Viral Vaccines and Vaccinations -- 8 Poliovirus Vaccines -- 9 Measles–Mumps–Rubella Vaccine -- 10 Varicella Vaccines -- 11 Rotavirus Vaccine -- 12 Hepatitis A Vaccines -- 13 Hepatitis B Vaccines -- 14 Influenza Vaccines -- 15 Human Papillomavirus Vaccines -- 16 Tick-Borne Encephalitis Vaccines -- Part 3 Bacterial Vaccines and Vaccination -- 17 Tuberculosis Vaccines -- 18 Pertussis Vaccines -- 19 Haemophilus influenzae type b (Hib) Vaccines -- 20 Pediatric Combination Vaccines -- 21 Pneumococcal Vaccines -- 22 Meningococcal Vaccines -- 23 Pediatric Vaccines for Travel Outside Europe -- Part 4 New Vaccines in Pipeline Development -- 24 GBS and CMV Vaccines in Pipeline Development -- 25 Norovirus Vaccines in Pipeline Development -- 26 RSV Vaccines and Monoclonal Antibodies in Development -- 27 COVID-19 in Children and COVID-19 Vaccines -- 28 Registration of Vaccines, Safety Follow-Up, and Pediatric Investigation Plan.
    Abstract: This second fully updated and extended edition of the textbook serves as a highly readable guide on latest developments in vaccine development and vaccination programs in infants, children and adolescents from a European perspective. The first part of the book introduces to general vaccinology, immunization programs and formulation, effects and unwanted effects of vaccines. The second and third part provide an overview on current viral and bacterial vaccines. The fourth and last part of this book discusses new vaccines in the pipeline and gives insights into safety and regulatory matters. This second edition is extended by a whole new chapter on COVID-19 vaccines. This book serves as a reference textbook in the field and helps to standardize the information on vaccines and immunization programs in the WHO European Region.
    Type of Medium: Online Resource
    Pages: XIII, 319 p. 66 illus., 63 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030771737
    DDC: 616.9041
    Language: English
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  • 36
    Keywords: Ecology . ; Conservation biology. ; Biotic communities. ; Population biology. ; Plant ecology. ; Animal culture. ; Ecology. ; Conservation Biology. ; Community and Population Ecology. ; Plant Ecology. ; Animal Science.
    Description / Table of Contents: Section 1 -- Chapter 1. Introduction -- Section 2. Plant Diversity -- Chapter 2. Status, issues and challenges of biodiversity:Lower plants (Non-vascular) -- Chapter 3. Status, issues and Challenges of Biodiversity:Higher Plants -- Chapter 4. Status, issues and challenges of biodiversity: Trees and Shrubs -- Chapter 5. Underutilized Plant Strength of India -- Section 3. Faunal Diversity -- Chapter 6. Status, Issues and Challenges of Biodiversity: Invertebrate -- Chapter 7. Diversity, Distribution and Endemicity of Herpetofauna in Different Biogeographic Zones and Biodiversity Hotpots of India -- Chapter 8. Status, Issues, and Challenges of Biodiversity: Wild Animals -- Chapter 9. Indian Avian Diversity:Status, Challenges and Solutions -- Chapter 10. Status, Issues and Challenges of Indian Livestock Biodiversity -- Section 4. Ecosystem Diversity -- Chapter 11. Agricultural Crop Diversity: Status, Challenges and Solutions -- Chapter 12. Biodiversity of Agriculturally Important Insects: Status, Issues and Challenges -- Chapter 13. Biodiversity Issues and Challenges:Non-Agriculture Insects -- Chapter 14. Status, issues and challenges of biodiversity: Forest Insects -- Chapter 15. Status, Issues and Challenges of Biodiversity: Marine Biota -- Chapter 16. Diatoms the living jewels their biodiversity, phycosphere and associated phenotypic plasticity: a lesson to learn from current pandemic of corona virus -- Chapter 17. Plant Diversity at Ecosystems level in India: Dynamics and Status -- Chapter 18. Faunal Diversity at Ecosystems level in India: Dynamics and Status -- Section 5. Challenges and reasons of Biodiversity loss -- Chapter 19. Challenges on Account of Invasive Alien Terrestrial Plants -- Chapter 20. Alien Invasive Aquatic Fauna:Challenges and Mitigation -- Chapter 21. Reasons of Biodiversity Loss in India -- Section 6. Efforts Conservation -- Chapter 22. Conservation of National Biodiversity: Efforts of the Indian Government -- Chapter 23. Legal Framework for Conservation of Biodiversity in India -- Chapter 24. Index.
    Abstract: This contributed book is based on the current status of biodiversity in India, issues and challenges faced by the authorities involved in conservation efforts, and the imperative role of various direct and indirect stakeholders in biodiversity conservation. The book discusses the current status of different forms of biodiversity in India, challenges faced by stakeholders, issues and reasons for biodiversity losses, and efforts by government through various laws, policies, and programs in a concise and comprehensive manner throughout its many chapters. In this way, readers can access diverse information on Indian biodiversity through this book. It is compiled by leading experts in the field of conservation. In 18 chapters, it covers biodiversity of both fauna and flora, on land and in aquatic ecosystems, legal and policy aspects, as well as innovative conservation tool and techniques. It is useful for undergraduates and graduate students and also educates policy planners, bureaucrats, foresters, and researchers in India and abroad.
    Type of Medium: Online Resource
    Pages: X, 665 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811697777
    DDC: 577
    Language: English
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  • 37
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biophysics. ; Cell interaction. ; Biomedical engineering. ; Cardiovascular system. ; Physiology. ; Cardiography. ; Molecular biology. ; Clinical biochemistry. ; Mechanobiological Cell Signaling. ; Biomedical Engineering and Bioengineering. ; Cardiovascular Physiology. ; Cardiography. ; Molecular Biology. ; Medical Biochemistry.
    Description / Table of Contents: Part 1: Cardiac Signaling -- Chapter 1: Calcium-Dependent Signaling in Cardiac Myocytes -- Chapter 2: Organization of Ca2+ Signaling Microdomains in Cardiac Myocytes -- Chapter 3: Stress Kinase Signaling in Cardiac Myocytes -- Chapter 4: Cardiotoxicity and cardiac cell signaling -- Chapter 5: Protein Phosphatase Signaling in Cardiac Myocytes -- Chapter 6: Metabolic Regulation of Mitochondrial Dynamics and Cardiac Function -- Chapter 7: NADPH Oxidase System Mediates Cholesterol Secoaldehyde-Induced Oxidative Stress and Cytotoxicity in H9c2 Cardiomyocytes -- Chapter 8: Lipid Mediators in Cardiovascular Physiology and Disease -- Chapter 9: Cardiac Inflammasome and Arrhythmia -- Chapter 10: Myocardial Fibrosis: Cell Signaling and In Vitro Modeling -- Chapter 11: Neural regulation of cardiac rhythm -- Part 2: Vascular Signaling -- Chapter 12: Mechanisms of lipoproteins and reverse cholesterol transport in atherosclerotic cardiovascular disease -- Chapter 13: Atherosclerotic plaque regression: Future perspective -- Chapter 14: Role of Bioactive Lipid, Phosphatidic Acid in Hypercholesterolemia Drug-induced Myotoxicity – Statin-induced Phospholipase D (PLD) Lipid Signaling in Skeletal Muscle Cells -- Chapter 15: Cell-Cell Communication in the Vascular Endothelium -- Chapter 16: Lysophosphatidic acid regulates endothelial barrier integrity -- Chapter 17: Regulation of Vascular Endothelial Barrier Integrity and Function by Lipid-Derived Mediators -- Chapter 18: Hyperglycemic Oxoaldehyde (Glyoxal)-induced Vascular Endothelial Cell Damage through Oxidative Stress is protected by Thiol Iron Chelator, Dimercaptosuccinic Acid – Role of Iron in Diabetic Vascular Endothelial Dysfunction.
    Abstract: This contributed volume focuses on cardiovascular diseases (CVDs), and explores the ways in which signaling mechanisms at the biochemical, molecular, and cellular levels in the blood vessels (vascular) and heart contribute to the underlying causes of development and progression of the CVDs. This volume covers unique topics such as oxidant signaling in vascular and heart diseases and health, cytoskeletal signaling in vascular health and disease, phospholipase signaling in CVDs, lipid signaling in vascular and myocardial health and diseases, and drug discovery in cellular signaling for cardiovascular diseases. This book assembles the most important discoveries made by leaders on the cellular signaling mechanisms operating behind the development and progression of life-threatening CVDs. It is an extremely useful resource for the investigators in the field of CVDs, and opens the discussion for further discovery of efficient management and effective treatment of the CVDs.
    Type of Medium: Online Resource
    Pages: XVIII, 527 p. 83 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031083099
    DDC: 571.4
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Parasitology. ; Internal medicine. ; Microbiology. ; Parasitology. ; Internal Medicine. ; Microbiology.
    Description / Table of Contents: Chapter 1. Parasite taxonomy, Classification of Zoonoses -- Chapter 2. Host Parasite Relationship and Spectrum of Clinical Manifestations -- Chapter 3. Parasitic Immunology -- Chapter 4. Parasite Genomics -- Chapter 5. Parasite Proteomics -- Chapter 6. Epidemiology of Parasitic Zoonoses -- Chapter 7. Diagnosis of Parasitic Zoonoses -- Chapter 8. Treatment and Management of Parasitic Zoonoses -- Chapter 9. Drug Resistance in Parasites -- Chapter 10. Zoonotic potential of Bioterrorism -- Chapter 11. Prevention, Surveillance, and Control of Parasitic Zoonoses -- Chapter 12. Toxoplasmosis -- Chapter 13. Giardiasis -- Chapter 14. Leishmaniasis -- Chapter 15. Trypanosomiasis -- Chapter 16. Malaria -- Chapter 17. Babesiosis -- Chapter 18. Cryptosporidiosis -- Chapter 19. Sarcocystosis. -- Chapter 20. Balantidiasis -- Chapter 21. Schistosomiasis -- Chapter 22. Fascioliasis -- Chapter 23. Fasciolopsiasis -- Chapter 24. Paragonomiasis -- Chapter 25. Echinostomiasis -- Chapter 26. Ophistorchiasis -- Chapter 27. Clonerchiasis -- Chapter 28. Heterophyes, Metagonimus, Dirocelium, Trogolotrema, and Watsonia infections -- Chapter 29. Diphyllobothriasis -- Chapter 30. Taeniasis -- Chapter 31. Echinococciasis -- Chapter 32. Sparganosis -- Chapter 33. Dipyllidiosis -- Chapter 34. Hymenolepsiasis -- Chapter 35. Coenurosis -- Chapter 36. Bertiella, Inermicapsifer, and Raillietinal infections -- Chapter 37. Trichinellosis -- Chapter 38. Dracunculiasis -- Chapter 39. Capillariasis -- Chapter 40. Strongyloidosis -- Chapter 41. Ancylostomiasis -- Chapter 42. Ascariasis -- Chapter 43. Dioctophymasis -- Chapter 44. Angiostrongylus and Trichostrongylus infections -- Chapter 45. Toxocariasis -- Chapter 46. Anisakiasis -- Chapter 47. Gnathostomiasis -- Chapter 48. Dirofilariasis -- Chapter 49. Thelaziasis -- Chapter 50. Gongylonemiasis -- Chapter 51. Termidens infections -- Chapter 52. Larva Migrans -- Chapter 53. Oesophagostomum and Mammomonogamus infections -- Chapter 54. Pentastomiasis -- Chapter 55. Scabies -- Chapter 56. Myiasis -- Chapter 57. Tungiasis -- Chapter 58. Ticks, Mites, Fleas -- Chapter 59. Allergenic MitesInfestations caused by Ectoparasites.
    Abstract: This textbook, which is the first volume in the series Microbial Zoonoses, provides a comprehensive overview of the diagnosis, treatment and control of zoonotic parasitic diseases. The book is divided into two sections; the first section discusses the classification of parasitic zoonoses and includes general information on the diagnosis, treatment, epidemiology, prevention, and control of parasitic zoonoses. It also describes the biological features of these organisms, host-parasite interactions, and the disease spectrum, as well as the importance of public health control measures, such as surveillance, and prophylactic measures in controlling these diseases. The second section explores the important zoonotic diseases caused by ectoparasites, protozoan and helminths parasites. It also reviews the life cycle, pathogenesis, pathology, immunology and clinical manifestations, modern diagnostic methods, treatment regimen, prevention, control, and epidemiology of these parasites. Cutting across the disciplines, this book serves as a guide to postgraduate students, faculty members, public health experts, and medical administrators who are interested in the management of these parasitic zoonotic infections.
    Type of Medium: Online Resource
    Pages: XXVII, 655 p. 239 illus., 219 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811672040
    Series Statement: Microbial Zoonoses,
    DDC: 571.999
    Language: English
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    Keywords: Agriculture. ; Botany. ; Agriculture. ; Plant Science.
    Description / Table of Contents: Preface -- Part I: Leaves -- Chapter 1. Advances in Chicory (Cichorium intybus L.) Breeding Strategies (Laila Aldahak, Khaled F. M. Salem, Salih H. F. Al-Salim, and Jameel M. Al-Khayri) -- Chapter 2. Chinese Cabbage (Brassica rapa L. var. pekinensis) Breeding: Application of Molecular Technology (Takumi Okamoto, Xiaochun Wei, Hasan Mehraj, Mohammad Rashed Hossain, Ayasha Akter, Naomi Miyaji, Yoshinobu Takada, Jong-In Park, Ryo Fujimoto, Ill-Sup Nou, and Masao Watanabe) -- Chapter 3. Breeding Advances and Prospects in Rocket Salad (Eruca vesicaria ssp. sativa Mill.) Cultivation (Pasquale Tripodi, Paula Santos Coelho, and Carla Guijarro-Real) -- Chapter 4. Spring Onion (Allium fistulosum L.) Breeding Strategies (Fatimah Kayat, Ahmed Mahmood Ibrahim, and Arifullah Mohammed) -- Chapter 5. Water Spinach (Ipomoea aquatica Forsk.) Breeding (Moumita Gangopadhyay, Anup Kumar Das, Subhendu Bandyopadyay, and Samanwita Das) -- Chapter 6. Watercress (Nasturtium officinale R. Br.) Breeding (Mohammadreza Hassandokht, Sajad Jafari, and Raheleh Ebrahimi) -- Part II: Flowerheads and Green Pods -- Chapter 7. Advances in Cauliflower (Brassica oleracea var. botrytis L.) Breeding, with Emphasis on India (Pritam Kalia and Shrawan Singh) -- Chapter 8. Globe Artichoke (Cynara cardunculus var. scolymus L.) Breeding (Fernando López-Anido and Eugenia Martin) -- Chapter 9. Breeding Strategies of Garden Pea (Pisum sativum L.) (Amal M.E. Abdel Hamid and Khaled F.M. Salem) -- Chapter 10. Genetic Improvement of Yardlong Bean (Vigna unguiculata (L.) Walp. ssp. sesquipedalis (L.) Verdc.) (Pidigam Saidaiah, Thuraga Vishnukiran, Someswar Rao Pandravada, Natarajan Sivaraj, Adimulam Srivani, Amarapalli Geetha, Nimmarajula Srinivas, and Venkateswaran Kamala) -- Part III: Mushrooms -- Chapter 11. Enoki Mushroom (Flammulina velutipes (Curtis) Singer) Breeding (Ved P. Sharma, Anupam Barh, Rakesh Kumar Bairwa, Sudheer K. Annepu, Babita Kumari and Shwet Kamal) -- Chapter 12. Shiitake Mushroom (Lentinula edodes (Berk.) Sing.) Breeding in China (Quanju Xiang, Bilal Adil, Qiang Chen, Yunfu Gu, Xianfu Zeng, and Xinzhu Li) -- Part IV: Truffles -- Chapter 13. Desert Truffles (Terfezia spp.) Breeding (Asunción Morte, Francisco Arenas, José E. Marqués-Gálvez, Alberto Andrino, Ángel L. Guarnizo, Almudena Gutiérrez, Luis Miguel Berná, Manuela Pérez-Gilabert, Antonio Rodríguez, and Alfonso Navarro-Ródenas) -- Chapter 14. Enhancing White Truffle (Tuber magnatum Picco and T. borchii Vittad.) Cultivation through Biotechnology Innovation (Alessandra Zambonelli, Mirco Iotti, Federico Puliga, and Ian R. Hall).
    Abstract: Plant breeders and geneticists are under constant pressure to sustain and expand food production by using innovative breeding strategies and introducing minor crops, which are well adapted to marginal lands, provide a source of nutrition, and have abiotic and biotic stress tolerance, to feed an ever-increasing human population. The basic concept of this book is to examine the use of innovative methods, augmenting traditional plant breeding, towards the improvement and development of new crop varieties, under the increasingly limiting environmental and cultivation factors, to achieve sustainable agricultural production and enhanced food security. Three volumes of the book series Advances in Plant Breeding Strategies were published in 2015, 2016 and 2018, respectively: Volume 1. Breeding, Biotechnology and Molecular Tools; Volume 2. Agronomic, Abiotic and Biotic Stress Traits and Volume 3. Fruits. In 2019, the following four volumes were published: Volume 4. Nut and Beverage Crops, Volume 5. Cereals, Volume 6. Industrial and Food Crops and Volume 7. Legumes. Recent volumes published in 2021 include: Volume 8. Vegetable Crops: Bulbs, Roots and Tubers, Volume 9. Vegetable Crops: Fruits and Young Shoots and Volume 10. Vegetable Crops: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles. This Volume 10, subtitled Vegetable Crops: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles, consists of 14 chapters focusing on advances in breeding strategies using both traditional and modern approaches for the improvement of individual vegetable crops. Chapters are arranged in 4 parts according to the edible vegetable parts. Part I: Leaves - Chicory, Chinese cabbage, Rocket salad, Spring onion, Water spinach and Watercress; Pat II: Flowerheads and Green Pods - Cauliflower, Globe artichoke, Garden pea and Yardlong bean; Part III: Mushrooms - Enoki mushroom and Shiitake mushroom; Part IV: Truffles - Desert truffles and White truffle. Each chapter comprehensively reviews the contemporary literature on the subject and reflects the experiences of the authors. Chapters are written by internationally-reputable scientists and subjected to a review process to assure quality presentation and scientific accuracy. Each chapter begins with an introduction covering related backgrounds and provides in-depth discussion of the subject supported with high-quality color photos, illustrations and relevant data. The chapter concludes with recommendations for future research directions, a comprehensive list of pertinent references to facilitate further reading, and appendixes of genetic resources and concerned research institutes. This book series is a valuable resource for advanced students, researchers, scientists, commercial producers and seed companies as well as consultants and policymakers interested in agriculture, particularly in modern breeding technologies.
    Type of Medium: Online Resource
    Pages: XVII, 540 p. 98 illus., 76 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030669690
    DDC: 630
    Language: English
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  • 40
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cytology. ; Bioinformatics. ; Imaging systems in biology. ; Cell Biology. ; Computational and Systems Biology. ; Biological Imaging.
    Description / Table of Contents: Introduction -- Batch Processing Methods in ImageJ -- Python: Data Handling, Analysis and Plotting -- Building a Bioimage Analysis Workflow Using Deep Learning -- GPU-Accelerating ImageJ Macro Image Processing Workflows Using CLIJ -- How to Do the Deconstruction of Bioimage Analysis Workflows: A Case Study with SurfCut -- i.2.i. with the (Fruit) Fly: Quantifying Position Effect Variegation in Drosophila Melanogaster -- A MATLAB Pipeline for Spatiotemporal Quantification of Monolayer Cell Migration.
    Abstract: This open access textbook aims at providing detailed explanations on how to design and construct image analysis workflows to successfully conduct bioimage analysis. Addressing the main challenges in image data analysis, where acquisition by powerful imaging devices results in very large amounts of collected image data, the book discusses techniques relying on batch and GPU programming, as well as on powerful deep learning-based algorithms. In addition, downstream data processing techniques are introduced, such as Python libraries for data organization, plotting, and visualizations. Finally, by studying the way individual unique ideas are implemented in the workflows, readers are carefully guided through how the parameters driving biological systems are revealed by analyzing image data. These studies include segmentation of plant tissue epidermis, analysis of the spatial pattern of the eye development in fruit flies, and the analysis of collective cell migration dynamics. The presented content extends the Bioimage Data Analysis Workflows textbook (Miura, Sladoje, 2020), published in this same series, with new contributions and advanced material, while preserving the well-appreciated pedagogical approach adopted and promoted during the training schools for bioimage analysis organized within NEUBIAS – the Network of European Bioimage Analysts. This textbook is intended for advanced students in various fields of the life sciences and biomedicine, as well as staff scientists and faculty members who conduct regular quantitative analyses of microscopy images.
    Type of Medium: Online Resource
    Pages: X, 212 p. 265 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030763947
    Series Statement: Learning Materials in Biosciences,
    DDC: 571.6
    Language: English
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  • 41
    Keywords: Plant anatomy. ; Stress (Physiology). ; Plants. ; Plant physiology. ; Plant ecology. ; Plants Development. ; Agriculture. ; Plant Anatomy and Morphology. ; Plant Stress Responses. ; Plant Physiology. ; Plant Ecology. ; Plant Development. ; Agriculture.
    Description / Table of Contents: Crosstalk between autophagy and hormones for abiotic stress tolerance in plants -- Abscisic acid and plant response under adverse environmental conditions -- Auxins and plant response to adverse environmental conditions -- Jasmonic acid for sustainable plant growth and production under adverse environmental conditions -- Salicylic acid for vigorous plant growth and enhanced yield under harsh environment -- Strigolactones for sustainable plant growth and production under adverse environmental conditions -- Polyamines for sustainable plant growth and production under adverse environmental conditions -- Plant performance and defensive role of proline under environmental stress -- Plant performance and defensive role of β-amino butyric acid under environmental stress -- Plant performance and defensive role of γ-gamma amino butyric acid under environmental stress -- Nitric oxide: A key modulator of plant responses under environmental stress -- Functions of hydrogen sulfide in plant regulation and response to abiotic stress -- Silicon and plant responses under adverse environmental conditions -- Nanofertilizers as tools for plant nutrition and plant biostimulation under adverse environment -- Biostimulants and plant response under adverse environmental conditions: a functional interplay -- Biofertilizers-mediated sustainable plant growth and production under adverse environmental conditions -- Seed priming: A cost-effective strategy to impart abiotic stress tolerance -- Significance of cyanobacteria in soil-plant system and for ecological resilience -- Phytomicrobiome community: An agrarian perspective -- Adverse environment and pest management for sustainable plant production -- Eco-friendly approaches of using weeds for sustainable plant growth and production.
    Abstract: Global climate change is bound to create a number of abiotic and biotic stresses in the environment, which would affect the overall growth and productivity of plants. Like other living beings, plants have the ability to protect themselves by evolving various mechanisms against stresses, despite being sessile in nature. They manage to withstand extremes of temperature, drought, flooding, salinity, heavy metals, atmospheric pollution, toxic chemicals and a variety of living organisms, especially viruses, bacteria, fungi, nematodes, insects and arachnids and weeds. Incidence of abiotic stresses may alter the plant-pest interactions by enhancing susceptibility of plants to pathogenic organisms. These interactions often change plant response to abiotic stresses. Plant growth regulators modulate plant responses to biotic and abiotic stresses, and regulate their growth and developmental cascades. A number of physiological and molecular processes that act together in a complex regulatory network, further manage these responses. Crosstalk between autophagy and hormones also occurs to develop tolerance in plants towards multiple abiotic stresses. Similarly, biostimulants, in combination with correct agronomic practices, have shown beneficial effects on plant metabolism due to the hormonal activity that stimulates different metabolic pathways. At the same time, they reduce the use of agrochemicals and impart tolerance to biotic and abiotic stress. Further, the use of bio- and nano-fertilizers seem to hold promise to improve the nutrient use efficiency and hence the plant yield under stressful environments. It has also been shown that the seed priming agents impart stress tolerance. Additionally, tolerance or resistance to stress may also be induced by using specific chemical compounds such as polyamines, proline, glycine betaine, hydrogen sulfide, silicon, β-aminobutyric acid, γ-aminobutyric acid and so on. This book discusses the advances in plant performance under stressful conditions. It should be very useful to graduate students, researchers, and scientists in the fields of botanical science, crop science, agriculture, horticulture, ecological and environmental science.
    Type of Medium: Online Resource
    Pages: XIV, 606 p. 54 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030785215
    DDC: 571.32
    Language: English
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  • 42
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Food science. ; Food Analysis. ; Chemistry. ; Sustainability. ; Food Engineering. ; Food Science. ; Food Chemistry. ; Sustainability.
    Description / Table of Contents: Part I: Introduction -- 1.Sustainability in food science and food industry: where are we now? – Viewpoints of the EFFoST Working Group on Sustainable Food Systems -- 2. Innovative processing: from raw material (culture), harvesting, post harvesting, processing, and applications -- Part II: Mechanism of action of nonthermal processing technologies (NTP) -- 3. Fundamental mechanisms of action -- 4. Electro-technologies: pulsed electric fields, cold plasma, radio-frequency and oscillating magnetic fields, electrohydrodynamic processing, electron beam processing and ionizing radiation -- 5. Pressure-based technologies: high pressure processing; supercritical and subcritical fluid processing -- 6. Mechanical technologies: ultrasound, and hydrodynamic cavitation -- 7. Non-electro-technologies: gamma rays, UV light, pulsed light, ozonation, photodynamic and membrane processing -- 8. Non-electro-technologies: gamma rays, UV light, ozone, photodynamic and membrane processing -- Part 3: Implementation of novel nonthermal technologies in agri-food-bio sciences -- 9. Nonthermal Processing Technologies: Synergies and new applications in food engineering -- 10. Implementation of novel nonthermal plasma air cleaner in a plant factory -- 11. LED-based photosensitization – a prospect for visible light-driven nonthermal fresh produce sanitation -- 12. Electrospinning Technology: Its Process Conditions and Food Packaging Applications -- 13. Application of encapsulation technology in the agri-food sector -- Part 4. Nonthermal processing legislation -- 14. Overview of legislation across the globe, diagnostics and standards which provide a legal and regulatory framework in which NTP is used worldwide -- 15. Current technology readiness levels (TRL) of nonthermal technologies and research gaps for improved process control and integration into existing production lines -- 16. Industry implementation (scale-up): Clients’ experience towards understanding of how regulations are affecting novel product development -- 17. Supercritical fluids as a tool for sustainable manufacturing of added value products -- Part 5 Mechanisms of validation of nonthermal processes in biomaterials and agri-food applications -- 18. Current validation of NTP technologies and overview of their current and potential implementation in the production chain including agri-food wastes -- Part 6. Sustainable perspective of nonthermal technologies -- 19. New product development from marine sources and side streams valorization using nonthermal processing technologies -- 20. Efficient production of functional and bioactive compounds and foods for use in food, pharma, cosmetic and other industries -- 21. Decontamination of fruit juices by combination of high intensity pulsed light and other nonthermal technologies -- 22. Food-On-A-Chip: Relevance of Microfluidics in food processing -- Part 7. Food waste management and sustainable parameters analysis -- 21. Analysis and comparison of environmental impacts of nonthermal food technologies -- 22. Emerging non-thermal processing of food waste and by-products for sustainable food systems - selected cases -- 23. Strategies for commercializing scientific results and combining separate processes into complex technologies -- 24 Sustainable processing through efficient use of energy and minimizing waste production -- 25. Food Safety and Security (HACCP and HAZOP) for Consumers and Workers (Nonthermal Technologies and their use) -- Part 8. Success stories of industrial implementation of nonthermal technologies -- 26.: Innovative success stories on commercial non-thermal technologies - interviews of major food industries working in this area. .
    Abstract: This book addresses important questions on the legislation, regulations, sustainability, technology transfer, safety of biomaterials and mechanism of action of nonthermal processing on the molecular level of biomaterials and its impact on health. The chapters take an interdisciplinary approach that is of interest to specialists from engineering, physics, chemistry, agriculture, life sciences and beyond, with a focus on further development of existing and new applications of nonthermal processing and their combination with other methods in the processing of biomaterials, agriculture, biotechnology and the re-use of waste and by-products. Nonthermal Processing in Agri-Food-Bio Sciences: Sustainability and Future Goals aims to boost further developments and applications of nonthermal technologies to develop healthier products, to ensure consumer approval for these innovative technologies and to improve the sustainability of biomaterials production. The industrial application of nonthermal processing has led to an increase in innovative value products and the overall improvement of production capacity. Nonthermal processes use less energy and chemicals, reduce processing times, have less environmental impact, produce less waste and have the potential for industrial scale-up and a return-on-investment in under 5 years. According to The United Nations and the 2030 Agenda for Sustainable Development, 17 goals should be incorporated within development projects, and researchers are starting to use novel techniques to meet them. In covering the fundamental engineering theories underlying nonthermal processing, this book will aid in this mission. The book overviews the advantages and disadvantages of novel technologies, over to sustainability goals to correct steps for the scale-up and return on investment. The book includes the chemistry and physics of nonthermal processing technologies, dedicated to specialists and researchers from a wide range of subject areas. Interdisciplinary scientists and engineers, sustainability experts can use this text to aid in their work in green technologies.
    Type of Medium: Online Resource
    Pages: VIII, 791 p. 124 illus., 74 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030924157
    Series Statement: Food Engineering Series,
    DDC: 664
    Language: English
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  • 43
    Keywords: Neurosciences. ; Animal culture. ; Veterinary medicine. ; Neuroscience. ; Animal Science. ; Veterinary Science.
    Description / Table of Contents: Rodents -- Carnivores -- Sheep and goats -- Swine -- Rabbits -- Bovines -- Non-human primates -- Humans -- Squirrels.
    Abstract: Modern neuroscience has presented new opportunities for exploring the molecular and neural mechanisms controlling specific social responses. This book reviews insights into the neural circuits underlying a particularly fascinating form of social interaction, parental behavior. This book presents a detailed review of maternal and paternal behavior of particular mammalian species. It offer neuroscientists a spectrum of specific mammals that can be used as experimental models to explore particular topics on the functions of the nervous system. It shows that results coming from the laboratory can be translated into useful information for raising mammals on the farm, and it stimulates biologists to gain insights into the underpinnings of the complex mechanisms governing mammalian behavior in the wild. It also discusses the implications of this research for human parental behavior. .
    Type of Medium: Online Resource
    Pages: V, 309 p. 45 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030977627
    Series Statement: Advances in Neurobiology, 27
    DDC: 612.8
    Language: English
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  • 44
    Keywords: Biotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Enzymology. ; Nanotechnology. ; Biotechnology. ; Microsystems and MEMS. ; Enzymology. ; Nanotechnology.
    Description / Table of Contents: Immobilization: Then and Now -- Cell immobilization strategies for tissue engineering: Recent trends and future perspectives -- Strategies and advancement in growth factor immobilizable ECM for tissue engineering -- Prospects Of Cell Immobilization In Cancer Research And Immunotherapy -- Nano systems for repairing retinal degeneration -- Systemic drug delivery to the posterior segment of the eye: Overcoming blood-retinal barrier through smart drug design and nanotechnology -- The effects of irradiation with cold atmospheric-pressure plasma on cellular function -- Immobilization of biomolecules on plasma functionalized surfaces for biomedical applications -- A wide portray of Upconversion-nanoparticles: surface modification for bio-applications -- Advances in Amphiphilic Assemblies and its Immobilization in Room Temperature Supercooled Matrices. .
    Abstract: This book delves into the field of immobilizing biologically active and non-active molecules. It discusses the designing strategy of immobilization and the current state-of-the-art applications for advancing biomedical, agricultural, environmental and industrial practices. It focuses on aspects ranging from fundamental principles to current technological advances at multi-scale levels (macro, micro, and nano) which are suitable for cell, enzyme, and nano-catalyst based applications. Written by experts from across the globe, the contents deal with illustrated examples of molecular and cellular interactions with materials/scaffolds and discussions on factors that can affect the functionality and yield of the process. With its discussions on material science, design of delivery vehicles, separation science, additive manufacturing, agriculture and environmental science, this book will be a useful reference for researchers across multiple disciplines.
    Type of Medium: Online Resource
    Pages: X, 666 p. 143 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811579981
    Series Statement: Gels Horizons: From Science to Smart Materials,
    DDC: 660.6
    Language: English
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  • 45
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Biophysics. ; Cell interaction. ; Cytology. ; Cancer Microenvironment. ; Mechanobiological Cell Signaling. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: Neuregulin signaling in the tumor microenvironment -- HGF/c-Met signalling in the tumor microenvironment -- Eph/ephrin signaling in the tumor microenvironment -- Src signaling in cancer and tumor microenvironment -- Purinergic signaling within the tumor microenvironment -- TGFβ signalling in the tumor microenvironment -- Wnt Signaling in the Tumor Microenvironment -- Lysophospholipid Signalling and the Tumour Microenvironment -- Adenosine signaling in the tumor microenvironment -- Androgen signaling in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 191 p. 31 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030471897
    Series Statement: Advances in Experimental Medicine and Biology, 1270
    DDC: 571.978
    Language: English
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  • 46
    Keywords: Phylogeny. ; Biology Technique. ; Gene expression. ; Bioinformatics. ; Phylogenetics. ; Gene Expression Analysis. ; Bioinformatics.
    Description / Table of Contents: Introduction to phylogenetic trees -- A divergence time story: the rise and fall of the molecular clock -- Estimating phylogenetic trees -- Estimating divergence times -- Estimating common ancestors -- Testing theories of molecular evolution -- Recommendations for further reading -- Appendix A: Intermittent point processes -- Appendix B: Poisson processes with Lévy-stable substitution rates.
    Abstract: This book serves as a brief introduction to phylogenetic trees and molecular evolution for biologists and biology students. It does so by presenting the main concepts in a variety of ways: first visually, then in a history, next in a dice game, and finally in simple equations. The content is primarily designed to introduce upper-level undergraduate and graduate students of biology to phylogenetic tree reconstruction and the underlying models of molecular evolution. A unique feature also of interest to experienced researchers is the emphasis on simple ways to quantify the uncertainty in the results more fully than is possible with standard methods.
    Type of Medium: Online Resource
    Pages: XIII, 106 p. 21 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031119583
    Series Statement: SpringerBriefs in Systems Biology,
    DDC: 576.88
    Language: English
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  • 47
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Geography. ; Environment. ; Power resources. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Regional Geography. ; Environmental Sciences. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Intro: Navigating Patagonian freshwaters- and this book -- 1: Are freshwaters wetlands? -- 2: Patagonian Andean lakes and climate change -- 3: Current state and recent changes of glaciers in the Patagonian Andes (35 °S to 55°S) -- 4: Biogeographical patterns of Patagonian freshwater microbiota -- 5: Extreme freshwater ecosystems from Patagonia: The Copahue-Agrio system -- 6: Mercury in aquatic systems of North Patagonia: sources, processes and trophic transfer -- 7: Diversity patterns across aquatic communities from peat bogs -- 8: Hydrologic Systems, water uses and emerging conflicts around freshwater availability in Patagonia -- 9: Land-use effects on aquatic ecosystems: An overview of environmental impacts and tools for ecological assessment -- 10: Patagonian wetlands: vertientes, vegas, mallines,turberas and lagunas -- 11: Fish and fisheries of the Patagonian steppe -- 12: Invasive species: The case of Didymosphenia geminata in Neuquén Province -- 13: Influence of the fish introduction in lakes of the arid Patagonia -- 14: Patagonian cultural limnology: knowledge and water management in Mapuche rural communities -- 15: Political Ecology, water valoration and Water Law deliberation in the Province of Tierra del Nacional de Tierra del Fuego -- 16: Freshwater systems in protected areas in Patagonia -- 17: Amphibians and waterbirds as bridges to conserve aquatic and terrestrial habitat in Patagonia -- 18: Integrated long term conservation strategies to recover the critically endangered Hooded Grebe (Podiceps gallardoi),an endemic waterbird of Austral Patagonia -- Conclusion: Reaching out for the UNDP Sustainable Development Goals in Patagonia.
    Abstract: The Freshwaters of Patagonia adopts a socioecological approach, in which experts from across Patagonia review recent, scientifically rigorous literature and data of their own, thus synthesizing the current knowledge directly relevant to understand the present state and future trends of icefields, freshwater and wetland ecosystems in this region. The book’s organization into three parts provides a studied and comprehensive view on the patterns and processes of the various ecosystems in Patagonia, and describes the sociological aspects of freshwater ecosystems, as well as characterizes the conservation of the freshwater and wetland ecosystems, in Patagonia. The chapters offer a broad, state-of-the-art overview of the current status of glaciers, freshwater and wetland ecosystems of this region, as well as studies of both local and large scale biodiversity patterns, and study cases of extreme and naturally polluted environments.The volume concludes with the current status of Patagonian freshwaters, and discusses the scientific, legal and administrative tools aimed at their sustainable management within the framework of the UNEP Sustainable Development Goals 2030 Agenda. A broad audience of students, scientists, engineers, environmental managers, and policy makers will be interested in this volume.
    Type of Medium: Online Resource
    Pages: XI, 541 p. 104 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031100277
    Series Statement: Natural and Social Sciences of Patagonia,
    DDC: 577.6
    Language: English
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  • 48
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical genetics. ; Medicinal chemistry. ; Nanomedicine. ; Cancer Treatment. ; Medical Genetics. ; Medicinal Chemistry. ; Nanomedicine and Nanotoxicology. ; Cancer Therapy.
    Description / Table of Contents: The Democratization of RNA Therapeutics -- Supramolecular Strategies for mRNA Delivery -- In Vitro-Transcribed mRNAs as a New Generation of Therapeutics in the Dawn of 21st Century: Exploitation of Peptides as Carriers for their Intracellular Delivery -- Effective Delivery of mRNA Therapeutics and Vaccines Using Lipid Nanoparticles -- Messenger RNA Therapeutics -- Formulation, Delivery and Application of mRNA Therapeutics In Respiratory Diseases -- Clinical Applications of mRNA Formulated In Lipid Nanoparticles -- Preparation of Messenger RNA Loaded Nanomedicine Applied on Tissue Engineering And Regenerative Medicine -- Lipid Nanoparticle-Mediated Delivery of mRNA Therapeutics: Immune Activation By Ionizable Cationic Lipids -- Adjuvants, the Elephant in the Room for RNA Vaccines -- Addressing Skin with Modified mRNA Constructs for Novel Therapies -- mRNA-Based Cancer Immunotherapies -- From Bench to Bedside: The Journey of an mRNA Drug Candidate Into a Medicine -- Synthetic mRNA Gene Therapies for Chronic HBV Infection -- Delivery Vehicles for Self-Amplifying RNA -- Delivery Technologies of mRNA Vaccines -- Nanosystems: The Key in Formulations of mRNA for Several Pathologies -- Messenger RNA Nanoformulation For Cancer Vaccine -- Preparation of Synthetic mRNAs for In Vivo Applications – Overview and Considerations -- Messenger RNA for Prophylaxis -- Nuclear Export of mRNA with Disease Pathogenesis and Therapeutic Potentials -- Messenger RNA Therapeutics: Start of a New Era in Medicine -- mRNA Delivery Technologies for Therapeutic Applications.
    Abstract: This book focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs. In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that protect the mRNA from nucleases and accelerate its cellular uptake, combined with improvements to the mRNA molecules themselves, have been critical advancements for mRNAs to become viable therapeutics. Though once regarded as a serious impediment, the transient nature of mRNA technology is now considered a major advantage in making mRNA therapies safe and, ultimately, a potential game changer in the field of medicine. This new book in the RNA Technologies series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic. mRNA-based approaches have great potential to revolutionize molecular biology, cell biology, biomedical research, and medicine. Thus, this handbook is an essential resource for researchers in academia and industry contributing to the development of this new area of therapeutics.
    Type of Medium: Online Resource
    Pages: XII, 446 p. 68 illus., 57 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031084157
    Series Statement: RNA Technologies, 13
    DDC: 616.042
    Language: English
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  • 49
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Oncology. ; Immunology. ; Metastasis. ; Cytology. ; Cancer Biology. ; Oncology. ; Immunology. ; Metastasis. ; Cell Biology.
    Description / Table of Contents: Chapter 1. A Systemic View of Metastatic Disease: Inter-organ Crosstalk and Therapeutic Implications -- Part I. Systemic Regulation in Metastatic Disease -- Chapter 2. Systemic Regulation of Metastatic Disease by Extracellular Vesicles and Particles -- Chapter 3. Bone Metastasis: Systemic Regulation and Impact on Host -- Chapter 4. Targeting Metastatic Disease: Challenges and New Opportunities -- Part II. Cachexia: A Debilitating Systemic Effect of Cancer -- Chapter 5. Signaling Pathways That Promote Muscle Catabolism in Cachexia -- Chapter 6. The Role of Interleukin-6 Cytokines in Cancer Cachexia -- Chapter 7. NF-kB Signaling in the Macroenvironment of Cancer Cachexia -- Part III. Therapy-induced Muscle Wasting -- Chapter 8. Therapy-induced Toxicities Associated with the Onset of Cachexia -- Chapter 9. Bone-muscle Crosstalk in Advanced Cancer and Chemotherapy -- Part IV. Preventing and Targeting Cachexia in Cancer -- Chapter 10. New Developments in Targeting Cancer Cachexia -- Chapter 11. Exercise: A Critical Component of Cachexia Prevention and Therapy in Cancer.
    Abstract: This textbook discusses the systemic consequences of cancer, covering a range of topics from tumor-promoting systemic effects to the development of cachexia, as summarized in the introductory chapter 1. Part I of this textbook focuses on tumor-promoting systemic effects and begins with a chapter on how tumor-derived extracellular vesicles and particles lay the foundation for future metastases (Chapter 2). Chapter 3 discusses how metastatic cells that have colonized the bone impact the local bone microenvironment, neighboring muscles, and host physiology. Chapter 4 summarizes the available strategies for targeting metastatic cancer and emphasizes the need to incorporate a systemic view of the disease. Following this overview of the systemic effects of cancer progression, Part II of the textbook discusses cancer-induced cachexia, a debilitating systemic effect of advanced cancer. Chapters 5-7 examine the key signaling pathways (interleukin-6/GP130, NF-kB, and muscle proteolysis) that drive the development of cancer cachexia. Chapters 8 and 9 in Part III of this textbook explore how toxicities from anti-cancer therapy are associated with the onset of cachexia in cancer patients, and provide insight into potential approaches to simultaneously target both cancer and cachexia. Chapters 10 and 11 (Part IV) conclude this textbook by outlining promising approaches for the diagnosis and treatment of cachexia as well as strategies to prevent the development of cachexia through exercise. An understanding of the systemic effects of cancer is essential for the design of effective anti-cancer and anti-cachexia treatment strategies. As such, this textbook provides key information for both students and scientists engaged in cancer research and oncology.
    Type of Medium: Online Resource
    Pages: VI, 203 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031095184
    DDC: 571.978
    Language: English
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  • 50
    Keywords: Human physiology. ; Medical education. ; Premedical education. ; Ultrasonics. ; Human Physiology. ; Medical Education. ; Premedical Education. ; Ultrasonics.
    Description / Table of Contents: Chapter 1: Using Ultrasound to Teach Physiology – An Introduction -- Chapter 2: The Basics of Ultrasound Physics -- Chapter 3: Ultrasound of the Vascular System -- Chapter 4: Ultrasound of the Heart -- Chapter 5: Ultrasound of the Respiratory System -- Chapter 6: Ultrasound of the Gastrointestinal System -- Chapter 7: Ultrasound of the Urinary System -- Chapter 8: Ultrasound of the Musculoskeletal System -- Chapter 9: Ultrasound of the Endocrine System -- Chapter 10: Ultrasound of the Reproductive System -- Chapter 11: Ultrasound of the Nervous System -- Chapter 12: Introducing Ultrasound into a Physiology Course from A to Z.
    Abstract: This book will be of interest to anyone who wants to use ultrasound to understand human physiology both in the clinical setting and the classroom. Tremendous advances in ultrasound technology have resulted in portable ultrasound systems that are easy to use, produce excellent images, and are affordable with quality hand-held and laptop-sized systems costing between $2K and $20K. These systems are now being used at the patient bedside or point of care by almost all medical and surgical specialities from primary care to orthopaedic surgery. These portable systems, especially the hand-held devices, are now being called the stethoscopes of the 21st century and will likely be used by many that are presently using stethoscopes including physicians, nurses, physician assistants, medics and other health professionals. Ultrasound began to be used in medical student education in the 1990s and is steadily becoming a common teaching tool for courses like anatomy and physiology. It is a visual, highly interactive learning tool that bridges the basic and clinical sciences and allows the learner to observe physiology principles in a living model. Ultrasound is also being used to teach other health professions students as well as undergraduate college students and high school students. Despite this interest there are no books available that provide an introduction to ultrasound and how it can be used to enhance the teaching of physiology. This e-book will do just that as well as offer “How to Scan” videos with example laboratory exercises to further engage learners.
    Type of Medium: Online Resource
    Pages: X, 323 p. 305 illus., 275 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9781071618639
    Series Statement: Physiology in Health and Disease,
    DDC: 612
    Language: English
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  • 51
    Keywords: Stress (Physiology). ; Plants. ; Molecular biology. ; Agriculture. ; Biotechnology. ; Plant Stress Responses. ; Molecular Biology. ; Agriculture. ; Biotechnology. ; Plant Signalling.
    Description / Table of Contents: 1. Targeted genome editing techniques in plant defense regulation -- 2. Synthetic promoters in regulating disease gene expression -- 3. Transcription factors associated with defense response against fungal biotrophs -- 4. Transcription factors associated with defense response against fungal necrotrophs -- 5. Transcription factors associated with defense response against viruses -- 6. Role of microbial bio-agents as elicitors in plant defense regulation -- 7. Transcriptional Factors Response under Biotic Stress in Wheat -- 8. Potential Transcription Factors for Biotic Stress Tolerance in Sugarcane -- 9. Role of transcription factors in response to biotic stresses in Maize -- 10. Role of transcription factors in response to biotic stresses in Pearl millet -- 11. Role of transcription factors in response to biotic stresses in Tomato -- 12. Role of transcription factors in response to biotic stresses in potato (Solanum tuberosum L.).
    Abstract: With the erratic changes in climate, crop plants are facing many forms of biotic stresses. When plants are under stress, among several gene families, regulatory genes play a vital role in signal transduction in modulating the expression of genes underpinning several defense pathways and targeting regulatory proteins (viz, transcription factors (TFs)) can be the alternative. Transcription factors directly regulate the downstream R genes and are excellent candidates for disease resistance breeding. Till date, numerous transcription factors have been identified and characterized structurally and functionally. Of them, TF families such as WRKY, NAC, Whirly, Apetala2 (AP2), ethylene responsive elements (ERF) etc. are found to be associated with transcriptional reprogramming of plant defense response. These TFs are responsive to the pathogen’s PAMPs/DAMPs - host’s PRR protein interactions and specifically binds to the cis-elements of defense genes and regulate their expression. With this background, realizing the importance of TFs in resistance breeding, this book discusses the recent research and developments in this field for various crops.
    Type of Medium: Online Resource
    Pages: VIII, 247 p. 26 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031129902
    DDC: 581.788
    Language: English
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  • 52
    Keywords: Neurosciences. ; Life sciences. ; Biology Technique. ; Evolution (Biology). ; Neuroscience. ; Life Sciences. ; Experimental Organisms. ; Evolutionary Biology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2.General Rules of Brain Morphogenesis in Vertebrates: An Hourglass Model -- Chapter 3.Neural Tube Formation -- Chapter 4.Subdivisions of Neural tube along the Dorsoventral Axis -- Chapter 5. Subdivisions of Neural Tube along the Rostrocaudal Axis: Neuromeric Models -- Chapter 6.Left-right Patterning of Neural Tube -- Chapter 7. Ventriculo-pial Patterning of Neural Tube -- Chapter 8.Development of Neural Circuits in Neural Tube -- Chapter 9.From Neural Tube to Larval Brain: Blood Vessels and Proliferative Zones -- Chapter 10. Development of Telencephalon -- Chapter 11. Development of Diencephalon, Optic Tectum, and Cerebellum -- Chapter 12. Nervous System in Medaka Larvae -- Chapter 13.From Larval Brain to Adult Brain and Summary of Telencephalic Ontogenesis -- Chapter 14. Adult Brain and General Brain Functions -- Chapter 15. Functional Neuroanatomy of Teleost Brains.
    Abstract: This book describes the developmental process of the brain of the medaka fish. It aims to understand the brain structure of vertebrates, including humans, by taking the brain of the medaka fish as an example and showing its actual developmental process. From developmental and evolutionary viewpoints, the understanding of the brain proceeds from simple to complex structures. Fish retain the basic form of vertebrates, and their brain morphology is relatively simple. Therefore, the fish brain is useful in understanding the brain structure. This book is unique for describing the entire process of the brain development in a specific fish. In addition, the book introduces the readers to a new concept of “Hourglass of Brain Morphogenesis”, concerning the general rule of brain morphogenesis in vertebrates. The authors propose that the brain morphology is highly conserved at the middle developmental stage but diverges more extensively at earlier and later stages. The new concept challenges the accepted theory that has been widely shared for about 200 years since K. von Baer (1828, 1837) and K. von Kupffer (1906) who proposed that three primary brain vesicles at earlier developmental stages develop into five secondary brain vesicles at later developmental stages in all vertebrates. The book provides a basic understanding of the vertebrate brain and is useful for all readers who wish to understand the complex structure of the brain. .
    Type of Medium: Online Resource
    Pages: XIV, 256 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811943249
    DDC: 612.8
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Epigenetics. ; Developmental biology. ; Evolutionary developmental biology. ; Molecular Evolution. ; Zoology. ; Evolutionary genetics. ; Epigenetics. ; Developmental Biology and Stem Cells. ; Evolutionary Developmental Biology. ; Molecular Evolution. ; Zoology. ; Evolutionary Genetics.
    Description / Table of Contents: Chapter 1. An Introduction to Epigenetics, Development, Ecology and Evolution. Chapter 2. Epigenetic Regulation: The Cross-Talk among Development, Adaptive Strategies, and Microevolutionary Change -- Chapter 3. Epigenetics and Phenotypic Plasticity in Animals -- Chapter 4. Role of Environmentally Induced Epigenetic Transgenerational Inheritance in Evolutionary Biology -- Chapter 5. Transgenerational Epigenetic Programming -- Chapter 6. Epigenetics, Evolution and Development of Birds -- Chapter 7. Epigenetics and the Extreme Stress Response -- Chapter 8. Epigenetic Adaptation to Local Ecologies as a First Step toward Gene: Culture Co-evolution.
    Abstract: Epigenetic modifications comprise heritable gene expression changes that occur without alteration of the DNA sequence and 'co-act' with genetic factors to shape development processes and evolutionary trajectories. Multicellular organisms receive different types of environmental stimuli/stresses that trigger epigenetic modifications during development. These environmentally driven mechanisms represent an underlying cause of phenotypic diversity, especially in metazoans. This book aims to present some of the latest epigenetic insights into the development of metazoans (including humans) as an intersection between their ecology and evolution.
    Type of Medium: Online Resource
    Pages: XII, 232 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031137716
    DDC: 572.865
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Microbial ecology. ; Biotechnology. ; Environment. ; Industrial microbiology. ; Bacteria. ; Microbial Ecology. ; Biotechnology. ; Environmental Sciences. ; Industrial Microbiology. ; Bacteria.
    Description / Table of Contents: Part 1. Climate Change and Microbial Ecology -- Chapter 1. Microbes and Climate: A tangled relation -- Chapter 2. Carbon sequestration in aquatic system using Microbial pump -- Chapter 3. Climate change extenuation by green house gas quenching microflora -- Chapter 4. Role of Methanotrophs in Mitigating Global Warming -- Chapter 5. Paradigm Ecological Shift and Succession in Microbiomes – A Climatic Advent -- Chapter 6. Exploring the diversity of marine microbiome in response to changes in the environment -- Chapter 7. Polar microbes as climate resilient pathways for mitigation of climate change -- Part 2. Climate Change and pathogens -- Chapter 8. Climate change and population health -- Chapter 9. Impact of Climate Change on the Incidence and Transfer of Food and Water borne Diseases -- Chapter 10. Climate change: any dangers from antimicrobial resistant bacteria? -- Chapter 11. Phyllosphere Microbiome: Plant defense strategies -- Part 3. Climate Change and Agriculture -- Chapter Chapter 12. Understanding Methanogens, Methanotrophs and Methane Emission in Rice Ecosystem -- Chapter 13. Soil micro-flora and its role in diminution of global climate change -- Chapter 14. Role of microorganisms in plant adaptation towards climate change for sustainable agriculture -- Chapter 15. Novel approaches for genome editing to develop climate smart crops -- Part 4. Climate change and the Environmental Microbiology -- Chapter 16. Role of soil microbial flora in remediation of hydrocarbon stressed soils -- Chapter 17. Biosurfactant Producing Bacteria as Potent Scavengers of Petroleum Hydrocarbons -- Chapter 18. Potent biotechnological applications of psychrozymes -- Chapter 19. Role of Green Nanotechnology in Alleviating Climate Change.
    Abstract: This book covers the contemporary environmental issues faced by life on the planet and the role planetary microbiomes play in such issues. Providing insights on the net favorable and adverse effect of microbial processes, this volume covers both the spontaneous and anthropocentric events that impact climate change and life on the planet. The book describes the ecological significance of microbiomes associated with the kingdoms Plantae and Animalia with respect to climate change, natural and anthropogenic causes of climate change, microbial interactions in nature, planetary microbiomes and food security, climate change in relation to disease epidemiology and human health and engineering microorganisms to mitigate the consequences of climate change. The individual chapters in the intended book provide both theoretical and practical exposure to the current issues and future challenges of climate change in relation to the microbiomes. This collection should serve as ready reference to the researchers working in the area to reshape their future research in addressing the challenges of global climate change.
    Type of Medium: Online Resource
    Pages: XIII, 374 p. 41 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813345089
    DDC: 579.17
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Genetics. ; Molecular biology. ; Cancer Biology. ; Genetics and Genomics. ; Molecular Biology.
    Description / Table of Contents: 1. Introduction to cancer -- 2. Oncogenes, signal transduction and the hallmarks of cancer -- 3. Tumor suppressor genes and cell fate control -- 4. Multi-step tumorigenesis and genome instability -- 5. Cancer genomics -- 6. Cancer epigenomics -- 7. Aging and cancer -- 8. Tumor microenvironment -- 9. Metastasis and cachexia -- 10. Cancer immunity -- 11. Architecture of cancer therapies.
    Abstract: Cancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone’s lifestyle decisions. The content of the book is linked to the lecture course in “Cancer Biology”, which is given by Prof. Carlberg since 2005 at the University of Eastern Finland in Kuopio. Moreover, biological processes explained in this book will be set into a clinical context using the experience of Dr. Velleuer in the daily care in oncology. This book also relates to the textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4), the studying of which may be interesting to readers who like to get more detailed information.
    Type of Medium: Online Resource
    Pages: XVII, 167 p. 72 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030756994
    DDC: 571.978
    Language: English
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    Keywords: Human physiology. ; Immune system. ; Cellular signal transduction. ; Respiratory organs. ; Physiology. ; Diseases. ; Human Physiology. ; Immune Cell Signalling. ; Respiratory Physiology. ; Diseases.
    Description / Table of Contents: Chapter 1. Introduction to Lung Diseases -- Chapter 2. Targeting molecular and cellular mechanisms in asthma.-Chapter 3. Various cellular and molecular axis involved in the pathogenesis of asthma -- Chapter 4. Targeting molecular and cellular mechanisms in steroid resistant asthma -- Chapter 5. Targeting molecular and cellular mechanisms in chronic obstructive pulmonary disease -- Chapter 6. Probing the cellular and molecular mechanisms underlying in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD) -- Chapter 7. Chronic obstructive pulmonary disease: Molecular basis of pathogenesis and targeted therapeutic approaches -- Chapter 8. Exploring the ‘dormancy-activation switch’ in the tumour microenvironment for metastatic lung cancer: The possible role of microRNA -- Chapter 9. Therapeutic strategies targeting signalling pathways in lung cancer -- Chapter 10. Modulation of signalling pathways by immunotherapeutics in lung cancer -- Chapter 11. Underpinning the Cellular and Molecular Mechanisms with Nanotheronstics for Lung Cancer -- Chapter 12. Targeting molecular and cellular mechanisms in Idiopathic Pulmonary Fibrosis.-Chapter 13. A refined approach to target the molecular and cellular mechanisms in pulmonary fibrosis.-Chapter 14. Targeting molecular and cellular mechanisms in tuberculosis -- Chapter 15. Cellular and Molecular Mechanisms of Repurposed antidiabetic drug as adjunctive treatment for tuberculosis -- Chapter 16. Targeting host and bacterial signaling pathways in tuberculosis: An effective strategy for the development of novel anti-tubercular therapies -- Chapter 17. Targeting molecular and cellular mechanisms in pulmonary hypertension -- Chapter 18. Targeting molecular and cellular mechanisms in pulmonary arterial hypertension -- Chapter 19. Potential cellular targets associated with the signaling and therapeutics of the pulmonary hypertension -- Chapter 20. Targeting molecular and cellular mechanisms in influenza A virus infections -- Chapter 21. Understanding the Biology of Non-typeable Haemophilus influenzae in Chronic Obstructive Pulmonary Disease through the Lens of Genomics -- Chapter 22. Targeting molecular and cellular mechanisms in rhinovirus infection -- Chapter 23. Targeting molecular and cellular mechanisms in respiratory syncytial virus (RSV) infection -- Chapter 24. Targeting molecular and cellular mechanisms SARS-CoV2 novel corona (COVID-19) virus infection -- Chapter 25. Underpinning the rudimentary mechanisms involved in the pathogenesis of SARS-CoV2 (COVID-19) in human lung cells -- Chapter 26. Targeting molecular and cellular mechanisms in SARS-CoV2 novel corona (COVID-19) virus infection -- Chapter 27. Special features of human lung ACE2 sensitivity to SARS CoV-2 spike glycoprotein -- Chapter 28. Implications of Phosphoinositide 3-kinase (PI3K) Signalling in cellular and molecular mechanisms of respiratory diseases -- Chapter 29. The role of the cholinergic system in lung diseases -- Chapter 30. The Nrf2-Keap1 signaling pathway in lung cancer -- Chapter 31. Role of Toll like receptor (LTR) in molecular and cellular mechanism of respiratory diseases -- Chapter 32. Biomarkers of Oxidative Stress -- Chapter 33. Targeting chronic lung diseases using advanced drug delivery systems -- Chapter 34. Plant based chemical moieties targeting cellular signalling pathways in chronic lung diseases -- Chapter 35. Role of phytoconstituents in targeting cytokines for managing pathophysiology of lung diseases -- Chapter 36. Targeting Cellular Signaling Pathways in Lung Cancer and Role of Phytochemicals as Novel Therapeutic Approach -- Chapter 37. Natural compounds targeting major signalling pathways in lung cancer -- Chapter 38. Drug delivery in respiratory diseases: Current opportunities, Molecular and cellular mechanism, and Future challenges -- Chapter 39. Future prospects and challenges in targeting cellular and molecular mechanisms in respiratory diseases.
    Abstract: The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.
    Type of Medium: Online Resource
    Pages: XIV, 926 p. 149 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813368279
    DDC: 612
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Invertebrates. ; Parasitology. ; Veterinary microbiology. ; Invertebrate Zoology. ; Parasitology. ; Veterinary Microbiology.
    Description / Table of Contents: 1.Origin and evolution of Triatominae -- 2. Taxonomy -- 3. Speciation Processes in Triatominae -- 4. Chromosome structure and evolution of Triatominae: A review -- 5. Embryonic development of the kissing bug Rhodnius prolixus -- 6. Anatomy of the nervous system of triatomines -- 7. Biogenic monoamines in the control of triatomine physiology with emphasis on Rhodnius prolixus -- 8. Structure and physiology of the neuropeptidergic system of triatomines -- 9. Sensory biology of triatomines -- 10. The behaviour of kissing-bugs -- 11. Features of interaction between triatomines and vertebrates based on bug feeding parameters -- 12. Blood Digestion in Triatomine Insects -- 13. The physiology of sperm transfer and egg production in vectors of Chagas disease with particular reference to Rhodnius prolixus -- 14. The Immune System of Triatomines -- 15. Interaction of triatomines with their bacterial microbiota and trypanosomes -- 16. The ecology and natural history of wild Triatominae in the Americas -- 17. Eco-epidemiology of vector-borne transmission of Trypanosoma cruzi in domestic habitats -- 18. Chagas Disease Vector Control -- 19. Insecticide resistance in triatomines -- 20. Perspectives in triatomine biology studies: “Omics”- based approaches.
    Abstract: This book aims to present updated knowledge on various aspects of the natural history, biology, and impact of triatomines to all interested readers. Each chapter will be written by authorities in the respective field, covering topics such as behavior, neurophysiology, immunology, ecology, and evolution. The contents will consider scientific, as well as innovative perspectives, on the problems related to the role of triatomine bugs as parasite vectors affecting millions in the Latin American region.
    Type of Medium: Online Resource
    Pages: XXX, 620 p. 62 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030645489
    Series Statement: Entomology in Focus, 5
    DDC: 592
    Language: English
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    Keywords: Cytology. ; Developmental biology. ; Zoology. ; Biochemistry. ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Cell Biology. ; Developmental Biology and Stem Cells. ; Zoology. ; Chemical Biology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Description / Table of Contents: Part 1 Pigments and pigment organelles -- 1 Pigments in insects -- 2 Melanins in vertebrates -- 3 Body color expression in birds -- 4 Pigments in teleosts and their biosynthesis -- 5 Bioluminescence and Pigments -- Part 2 Pigment cell and patterned pigmentation -- 6 Development of melanin-bearing pigment cells in birds and mammals -- 7 Pigment cell development in teleosts -- 8 Pigment patterning in teleosts -- 9 Theoretical studies of pigment pattern formation -- 10 Evolution of Pigment Pattern Formation in Teleosts -- 11 Mechanisms of feather structural coloration and pattern formation in birds -- 12 Mechanism of color pattern formation in insects -- Part 3 Color changes -- 13 Physiological and Morphological Color Changes in Teleosts and in Reptiles -- 14 Color change in cephalopods -- 15 Physiological and biochemical mechanisms of insect color change towards understanding molecular links.
    Abstract: This book comprehensively summarizes the biological mechanisms of coloration and pattern formation of animals at molecular and cellular level, offering up-to-date knowledge derived from remarkable progress in the last 10 years. The brilliant coloration, conspicuous patterns and spectacular color changes displayed by some vertebrates and invertebrates are generally their strategies of the utmost importance for survival. Consists of mainly three parts, starts with introductory chapter, such as Pigments and Pigment Organelles, Developmental Genetics of Pigment Cell Formation, Adult Pigment Patterns, and Color Changes, this book introduces new pigment compounds in addition to classically known pigments and organelles, explains how the generation of multiple types of pigment cell is genetically controlled, describes the mechanisms underlying the zebrafish stripe formation as well as other animals and also summarizes the mechanism of physiological and morphological color changes of teleost, amphibian and cephalopod. Written by experts in the field, this book will be essential reading for graduate students and researchers in biological fields who are interested in pigmentation mechanisms of animals.
    Type of Medium: Online Resource
    Pages: XII, 472 p. 192 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811614903
    DDC: 571.6
    Language: English
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    Keywords: Nervous system Surgery. ; Neuropsychology. ; Neurology . ; Neurosurgery. ; Neuropsychology. ; Neurology.
    Description / Table of Contents: Foreword -- Preface -- Part I: Sensorimotor and visuo-spatial functions -- 1. Motor control -- 2. Vision -- 3. FEF -- 4. Spatial cognition -- Part II: Language functions -- 5. Lexical access -- 6. Spontaneous speech -- 7. Reading -- 8. Writing -- 9. Repeating -- 10. Syntactic abilities -- 11. Verbs versus nouns naming -- 12. Verbal short-term memory -- 13. Proper names retrieval -- 14. Bilingual patients -- Part III: Higher-order functions -- 15. From verbal to non-verbal semantics -- 16. Inhibition -- 17. Set-shifting -- 18. Social cognition -- 19. Multitask mapping -- Part IV: Prospects -- 20. Creativity -- 21. Psychiatric and behavorial traits -- 22. Awake surgery in patients with poor abilities of verbal communication -- 23. Can we map inner speech? -- 24. Beyond tasks: when experience shapes intuition.
    Abstract: This book aims to give the state-of-the-art of intraoperative brain function mapping for resection of brain tumors in awake conditions, and to become a reference for acquiring the fundamental expertise necessary to select the right intraoperative task at the right time of the surgery. The chapters, all focused on a specific brain function, are divided in 4 parts: sensori-motor and visuo-spatial functions, language functions, higher-order functions, and prospects. Each chapter follows the same outline, including a brief review of the current knowledge about the networks sustaining the function in healthy subjects, the description of the intraoperative tasks designed to monitor the function, a review of the literature describing the deficits in that function after surgery, and a critical appraisal of the benefit provided by intraoperative mapping of that function.
    Type of Medium: Online Resource
    Pages: XIV, 421 p. 93 illus., 90 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030750718
    DDC: 617.48
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Diseases. ; Immunology. ; Bioinformatics. ; Cancer Biology. ; Diseases. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Obesity induced chronic low-level inflammation and cancers -- Chapter 2. Adipose tissue produced estrogen as risk factor for cancers -- Chapter 3. Insulin and Insulin-like growth factor-1 associated cancers.-Chapter 4. Adipokines play important role in cell proliferation and antiproliferation -- Chapter 5. mTOR and AMP-activated protein kinase in obesity and cancer -- Chapter 6. Immune response and oxidative stress in obesity induced cancer -- Chapter 7. Role of gene polymorphism in obesity and cancer -- Chapter 8. Therapeutic role of green tea in obesity and cancer -- Chapter 9. Effect of dietary phytochemicals in obesity and cancer -- Chapter 10. Resveratrol as anti-obesity and anticancer agent -- Chapter 11. EGCG as anti-obesity and anticancer agent -- Chapter 12. miRNAs as therapeutic target in obesity and cancer -- Chapter 13. In silico updates on lead identification for obesity and cancer -- Chapter 14. In vivo models for obesity and obesity related carcinogenesis -- Chapter 15. Estrogen signaling based current and potential therapies against obesity and related diseases -- Chapter 16. Autophagy at the crossroad of obesity mediated cancer progression.
    Abstract: This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development. The book is a useful resource for researchers in the field of cancer, pharmacology, food chemistry, and clinical biochemistry. .
    Type of Medium: Online Resource
    Pages: IX, 361 p. 38 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811618468
    DDC: 571.978
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Artificial intelligence. ; Artificial Intelligence.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Literature Review -- Chapter 3. Data Analysis -- Chapter 4. SynTime: Token Types and Heuristic Rules -- 5. TOMN: Constituent-based Tagging Scheme -- Chapter 6. UGTO: Uncommon Words and Proper Nouns -- Chapter 7. Conclusion and Future Work.
    Abstract: This book presents a synthetic analysis about the characteristics of time expressions and named entities, and some proposed methods for leveraging these characteristics to recognize time expressions and named entities from unstructured text. For modeling these two kinds of entities, the authors propose a rule-based method that introduces an abstracted layer between the specific words and the rules, and two learning-based methods that define a new type of tagging scheme based on the constituents of the entities, different from conventional position-based tagging schemes that cause the problem of inconsistent tag assignment. The authors also find that the length-frequency of entities follows a family of power-law distributions. This finding opens a door, complementary to the rank-frequency of words, to understand our communicative system in terms of language use.
    Type of Medium: Online Resource
    Pages: XIX, 96 p. 17 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030789619
    Series Statement: Socio-Affective Computing, 10
    DDC: 006.3
    Language: English
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    Keywords: Bioinformatics. ; Biology Technique. ; Life sciences. ; Bioinformatics. ; Computational and Systems Biology. ; Biological Techniques. ; Life Sciences.
    Description / Table of Contents: Chapter 1. Prelusion Significance of Livestock -- Chapter 2. Mass Balance concept in Livestock Farming -- Chapter 3. Goat and Sheep Farming -- Chapter 4. Cattle and Buffaloes Farming -- Chapter 5. Factors Influencing Livestock Way of Life -- Chapter 6. Sustainable Livestock Farming -- Chapter 7. Conceptual Development of Livestock Supply Chain Management.
    Abstract: Basic principles of applied life sciences such as recombinant DNA technology is used in most life sciences industries marketing bio-formulations for designing more effective protein-based drugs, such as erythropoietin and fast-acting insulin etc. In recent times genetically engineered host cells from mammal, animal and plants are also being used in life sciences industries to manufacture biologics. This book discusses the most basic as well advanced issues on biological products for successfully managing a life sciences industry. It elucidates the life cycle of biological molecules, right from the conceptual development of different types of biopolymers, and their subsequent transfer from the conical flasks in laboratory to life sciences industries for large scale production and marketing. It focuses on sustainable longevity in the life cycle of commercial biopolymers. Cumulative facts and figures in this volume would immensely help in inspiring life sciences industry promoters to monitor value chain transfer process of biologics for better profitability. Additionally, it would serve as a perusal document for the students and researchers interested in entrepreneurial ventures or having their own start-up projects for the commercialization of biologics. .
    Type of Medium: Online Resource
    Pages: XVI, 207 p. 101 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811620515
    Series Statement: New Paradigms of Living Systems, 2
    DDC: 570.285
    Language: English
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    Keywords: Agriculture. ; Botany. ; Agriculture. ; Plant Science.
    Description / Table of Contents: Preface -- Part I: Bulbs -- Chapter 1. Traditional and Novel Approaches in Garlic (Allium sativum L.) Breeding (Einat Shemesh-Mayer and Rina Kamenetsky Goldstein) -- Chapter 2. Genetic Improvement of Leek (Allium ampeloprasum L.) (Fevziye Celebi-Toprak and Ali Ramazan Alan) -- Chapter 3. Shallot (Allium cepa L. Aggregatum group) Breeding (Haim D. Rabinowitch) -- Part II: Roots -- Chapter 4. Molecular Breeding Strategies of Beetroot (Beta vulgaris ssp. vulgaris var. conditiva Alefeld) (Farrag F.B. Abu-Ellail, Khaled F.M. Salem, Maysoun M. Saleh, Lina M. Alnaddaf, and Jameel M. Al-Khayri) -- Chapter 5. Carrot (Daucus carota L.) Breeding (Philipp W. Simon) -- Chapter 6. Parsnip (Pastinaca sativa L.) Breeding for the Future (Lauren H.K. Chappell and Adrian J. Dunford) -- Chapter 7. Radish (Raphanus sativus L.): Breeding for Higher Yield, Better Quality and Wider Adaptability (Binod Kumar Singh) -- Chapter 8. Sugar Beet (Beta vulgaris ssp. vulgaris L.) Improvement with Next-generation Breeding Technology (Chiara De Lucchi, Enrico Biancardi, George Skaracis, Marco De Biaggi, Ourania Pavli, Samathmika Ravi, Claudia Chiodi, Chiara Broccanello, and Piergiorgio Stevanato) -- Chapter 9. Turnip (Brassica rapa var. rapa L.) Breeding (Hesham S. Abdel-Razzak) -- Part III: Tubers -- Chapter 10. Recent Advances in Potato (Solanum tuberosum L.) Breeding (Emre Aksoy, Ufuk Demirel, Allahbakhsh Joiya, Muhammad Abu Bakar Zia, Muhammad Naeem Sattar, Faisal Saeed, Sevgi Çalışkan, and Mehmet Emin Çalışkan) -- Chapter 11. Application of Genome Editing Tools to Accelerate Potato (Solanum tuberosum L.) Breeding (Zafar Iqbal and Muhammad Naeem Sattar) -- Chapter 12. Sweet potato (Ipomoea batatas L.) Breeding (Jolien Swanckaert, Dorcus Gemenet, Noelle L. Anglin, and Wolfgang Grüneberg).
    Abstract: Plant breeders and geneticists are under constant pressure to sustain and expand food production by using innovative breeding strategies and introducing minor crops, which are well adapted to marginal lands, provide a source of nutrition, and have abiotic and biotic stress tolerance, to feed an ever-increasing human population. The basic concept of this book is to examine the use of innovative methods, augmenting traditional plant breeding, towards the improvement and development of new crop varieties, under the increasingly limiting environmental and cultivation factors, to achieve sustainable agricultural production and enhanced food security. Three volumes of the book series Advances in Plant Breeding Strategies were published in 2015, 2016 and 2018, respectively: Volume 1. Breeding, Biotechnology and Molecular Tools; Volume 2. Agronomic, Abiotic and Biotic Stress Traits and Volume 3. Fruits. In 2019, the following four volumes were published: Volume 4. Nut and Beverage Crops, Volume 5. Cereals, Volume 6. Industrial and Food Crops and Volume 7. Legumes. Recent volumes published in 2021 include: Volume 8. Vegetable Crops: Bulbs, Roots and Tubers, Volume 9. Vegetable Crops: Fruits and Young Shoots and Volume 10. Vegetable Crops: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles. This Volume 8, subtitled Vegetable Crops: Bulbs, Roots and Tubers, consists of 12 chapters focusing on advances in breeding strategies using both traditional and modern approaches for the improvement of individual vegetable crops. Chapters are arranged in 3 parts according to the edible vegetable parts. Part I: Bulbs - Garlic, Leek and Shallot; Part II: Roots - Beetroot, Carrot, Parsnip, Radish, Sugar beet and Turnip, Part III: Tubers - Potato and Sweet potato. Each chapter comprehensively reviews the contemporary literature on the subject and reflects the experiences of the authors. Chapters are written by internationally-reputable scientists and subjected to a review process to assure quality presentation and scientific accuracy. Each chapter begins with an introduction covering related backgrounds and provides in-depth discussion of the subject supported with high-quality color photos, illustrations and relevant data. The chapter concludes with recommendations for future research directions, a comprehensive list of pertinent references to facilitate further reading, and appendixes of genetic resources and concerned research institutes. This book series is a valuable resource for advanced students, researchers, scientists, commercial producers and seed companies as well as consultants and policymakers interested in agriculture, particularly in modern breeding technologies.
    Type of Medium: Online Resource
    Pages: XV, 554 p. 105 illus., 86 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030669652
    DDC: 630
    Language: English
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    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. Using electrical stimulation to explore and augment the functions of parietal-frontal cortical networks in primates -- 2. Multi-system benefits of epidural stimulation following spinal cord injury. 3. Neurostimulator for hippocampal memory prosthesis -- 4. Modern approaches to augmenting the brain functions -- 5. Brain machine interfaces within a critical perspective -- 6. An implantable wireless device for ECoG and cortical stimulation -- 7. BCI Performance improvement by special low jitter quasi-steady State VEP paradigm -- 8. Communication with Brain-Computer Interfaces in Medical Decision-Making -- 9. Neuroprotection and neurocognitive augmentation by photobiomodulation -- 10. Avoiding partial sleep - the way for augmentation of brain function -- 11. Augmentation of brain functions by nanotechnology -- 12. The impact of ageing and age-related comorbidities on stroke outcome in animal models and humans -- 13. Diagnostic markers of sub-clinical depression based on functional connectivity -- 14. Transcranial magnetic stimulation in autism spectrum disorders: modulating brainwave abnormalities and behaviors -- 15. Neurofeedback training with concurrent psychophysiological monitoring in children with autism spectrum disorder with comorbid attention deficit/hyperactivity disorder -- 16. Augmentation through interconnection: brain-nets and telemedicine -- 17. Cognitive augmentation via a brain/cloud interface -- 18. Augmentation of neuro-marketing by neural technology -- 19. Augmentation of nutrition by nanotechnology -- 20. Neural spintronics: noninvasive augmentation of brain functions -- 21. Does the power to suppress an action make us free? -- 22. Deep brain stimulation for Parkinson’s disease-future directions for enhancing motor function -- 23. Neuromodulation for gait -- 24. Augmentation and rehabilitation with active orthotic devices -- 25. Effects of rTMS on behavioral and electrocortical measures of error monitoring and correction function in children with autism spectrum disorder -- 26. Affective Virtual Reality Gaming for Autism -- 27. A machine learning approach to automatic phobia therapy with virtual reality -- 28. Vision augmentation by pharmacological enhancement of the visual experience -- 29. Cognitive enhancing substances and the developing brain: risks and benefits -- 30. Pharmacological approaches in the augmentation and recovery of brain function.
    Abstract: This book covers recent advances in the neural technology that produces enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the behavior and mind. Augmentation of brain function is achieved using brain implants for recordings, stimulation and drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. Existing methods of brain augmentation are evaluated, and new approaches are introduced. Brain circuitry and neuronal mechanisms that are candidates for augmentation are discussed. This volume provides novel insights into brain disorders, and new devices for brain repair. Information in this book is relevant to researchers in the field of neuroscience, engineering, and clinical practice. Philosophical and ethical implications of brain augmentation are also addressed. “This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity.” – Ray Kurzweil "This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. " – Ioan Dumitrache “This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication.” – György Buzsáki.
    Type of Medium: Online Resource
    Pages: XXII, 747 p. 189 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030545642
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 65
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botanical chemistry. ; Food science. ; Plant physiology. ; Biotechnology. ; Plant Biochemistry. ; Food Science. ; Plant Physiology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Search of Sweeteners, their general classification, synthesis, and saccharide sweeteners plant - animal interphases -- Chapter 3. Molecular basis of sweetness and recent concepts, An ideal sweetener and saccharide and non-saccharide sweet principles qualifying it -- Chapter 4. Saccharide sweet (SS) principles, classification and structural and functional details of SS sweeteners and plants -- Chapter 5. Non saccharide super sweet principles, their general characteristics, outline of synthesis, classification, ecological significance and eco-friendly adherence -- Chapter 6. Perillartine (Mono-terpenoid) -- Chapter 7. Steviosides (Diterpenoids) -- Chapter 8. Triterpenoids -- Chapter 9. Hernandulcin: (Sesquiterpene) -- Chapter 10. Falvonoid Super Sweet Principles Dihydrochalcone -- Chapter 11. PHYLLODULCIN -- Chapter 12. Osladin, Polypodoside A, B, and C (Steroidal saponins) -- Chapter 13. Monatin:(Super Sweet Amino acid) -- Chapter 14. Super sweet and taste modifier proteins -- Chapter 15. Vegetal Taste modifiers -- Chapter 16. Eco-Physiological difference between sacchariferous sweet (SS) and non sacchariferous super sweet (NSSS) principles and Plants -- Chapter 17. Molecular approaches for the improvement of Non sacchariferous super sweet (NSSS) plants -- Chapter 18. Commercial Production of natural NSSS sweeteners-A concised sketch.
    Abstract: This book gathers the latest information on various kinds of natural, plant-based sweet and super sweet sweeteners. A book on alternative, natural sweeteners with zero or very few calories is extremely timely and useful, especially in light of the decreasing amount of cultivable land, ever-increasing demand for sucrose, and the well-known risks of sugar consumption. Every year, more than five million people die due to diabetes and diabetes-associated diseases like cardiovascular conditions, kidney disorders, liver cancer, etc. This book describes the use of natural non-saccharide super sweet (NSSS) principles to avoid such maladies. Readers will gain an in-depth understanding of various sweeteners, the molecular basis of sweetness, sweeteners’ general classification, plant sources, etc. In turn, the book focuses on the propagation, cultivation and conservation of NSSS plants (NSSSP) and extraction of super sweet principles and granting of Generally Recognised As Safe (GRAS) certificates for sweeteners. The closing chapter describes the eco-physiological difference between sacchariferous sweet and non-sacchariferous super sweet plants and principles. This book will be of great interest to researchers, professors, graduate students and practitioners in the fields of food science, nutrition, ayurveda, plant physiology, unani, chemotaxonomy, naturopathy, biochemistry and plant breeding. It will also be of interest to industry and alternative sweetener manufacturers.
    Type of Medium: Online Resource
    Pages: XXIX, 773 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789813363502
    DDC: 572.2
    Language: English
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  • 66
    Keywords: Immunology. ; Molecular biology. ; Nutrition   . ; Cytology. ; Biology. ; Immunology. ; Molecular Biology. ; Nutrition. ; Cell Biology. ; Biological Sciences.
    Description / Table of Contents: Chapter 1. Nanotechnology based bacterial immunotherapy -- Chapter 2. Immunomodulatory properties of nutraceuticals and functional foods -- Chapter 3. Immunoregulatory bioactive phytoconstituents- recent trends and future challenges -- Chapter 4. Plant derived immunomodulators and immune system -- Chapter 5. Polyphenols and its effect on immune system -- Chapter 6. Mineral nutraceuticals and immunity enhancement -- Chapter 7. Nutraceuticals as disease preventive food and immunity boosters -- Chapter 8. Current and Future prospects of flavonoids for human Immune system -- Chapter 9. Resveratrol and immunomodulation -- Chapter 10. Immunomodulation impact of curcumin and its derivative as a natural ingredient -- Chapter 11. Colchicine and andrographolide as natural immunomodulators -- Chapter 12. Immune booster property of epigallocatechin-3-gallate and catechin -- Chapter 13. Recent advances of nutraceutical and functional foods in immune health -- Chapter 14.Therapeutic effects of Withania somnifera-an overview with special focus on Alzheimer’s disease and infertility among youth.
    Abstract: This book provides valuable coverage on various immunomodulatory research associated with nutraceutical studies, from plant to animal and marine sources. The book focuses on the various properties of nutraceutical and functional foods, from dietary fibers to fungus, marine sources, ginseng, and several others. Its content is also dedicated to the nutraceutical potential and applications of these modulators. The first section of this book focuses mainly on the recent developments in nutraceutical and functional food associated with various immunomodulators. The next section covers the micronutrients and macronutrients level in order to share important data and help readers gain a basic understanding of the techno-functional, nutraceutical potential and applications of nutritional treatment under specific disease conditions. A detailed overview providing the structural and functional properties related to immunomodulators will be highly beneficial for academics and advanced-level students in immunology, food science, clinical medicine, and life sciences.
    Type of Medium: Online Resource
    Pages: XII, 348 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811925078
    DDC: 571.96
    Language: English
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  • 67
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Agriculture. ; Agriculture.
    Description / Table of Contents: Chapter 1 The Role of Skepticism in Science? -- Chapter 2 Warnings for Skeptics -- Chapter 3 Photosynthesis -- Chapter 4 Seed Number -- Chapter 5 Nitrogen Use Efficiency -- Chapter 6 Water Use Efficiency -- Chapter 7 Water Loss -- Chapter 8 Unconfirmed Field Observations (UFOs).
    Abstract: Global food production and climate change among other concerns are societal issues that require major research input from crop science. While suggestions are abundant on how crop science can help to resolve these issues, many of the suggestions come from people who are not actually familiar with the challenges and requirements to modify crop plants grown under field conditions to achieve the necessary improvements. Efforts to alter a gene or even several genes have very rarely proven successful in having impact on crop production under realistic field conditions. This lack of success has not been addressed head on. This book serves as a reminder to crop scientists and others that open, clear-minded assessments of the entirety of evidence concerning a hypothesis is required before making claims of possible increases in crop performance. This attitude of skepticism is not a negative attitude but rather an employment of the cornerstone of scientific investigation based on formation and evaluation of hypotheses. Skeptical analyses are to be presented in the book on some of the common suggestions for improving crop plants. The six specific topics to be addressed are photosynthesis, seed number, nitrogen use efficiency, water use efficiency, crop water loss, and unconfirmed field observations. Each of the topics in this book, will first be reviewed to present the origins of the popular assumptions about how specific plant modification will result in improved crop performance. The review of the background information will be followed by an examination of the evidence, logic, and predicted outcomes for the assumed benefits of the modifications. Finally, each chapter will offer novel, alternate approaches to plant modification that have documented support for positively impacting crop performance. The book will not be written in specialized, detail language but offer access for those with a wide range of interests in options for increasing crop production in the future. The goal of the book is to provide information that is useful to those with interests ranging from climatologist to food-oriented sociologists. Of course, the topics covered will be of direct interest to those studying plant sciences, particularly crop scientists. The hope is to challenge a reader to re-examine some of her/his assumptions about crop improvement and approach the topic with a renewed practice of skepticism in formulating and evaluating hypotheses. .
    Type of Medium: Online Resource
    Pages: VI, 66 p. 32 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031144141
    Series Statement: SpringerBriefs in Agriculture,
    DDC: 630
    Language: English
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  • 68
    Keywords: Zoology. ; Environment. ; Bioinformatics. ; Ecology . ; Biodiversity. ; Physical geography. ; Zoology. ; Environmental Sciences. ; Computational and Systems Biology. ; Ecology. ; Biodiversity. ; Earth System Sciences.
    Description / Table of Contents: Introduction -- Historical review of research on Arctic and Subarctic Aleocharinae -- Material and methods -- Impact of climate change on northern fauna and flora -- Aleocharinae as indicators of change -- Faunal analysis and discussion -- Key to tribes occurring in Arctic and Subarctic zones -- Tribe Gymnusini Heer, 1839 -- Tribe Aleocharini Fleming, 1821 -- Tribe Oxypodini C.G. Thomson, 1859 -- Tribe Tachyusini C.G. Thomson, 1859 -- Tribe Hypocyphtini Laporte, 1835 -- Tribe Myllaenini Ganglbauer, 1895 -- Tribe Liparocephalini Fenyes, 1918 -- Tribe Homalotini Heer, 1839 -- Tribe Placusini Mulsant and Rey, 1871 -- Tribe Athetini Casey, 1910 -- Tribe Falagriini Mulsant and Rey, 1873.
    Abstract: Arctic and Subarctic North America is particularly affected by climate change, where average temperatures are rising three times faster than the global average. Documenting the changing climate/environment of the north requires a structured knowledge of indicator taxa that reflect the effects of climate changes. Aleocharine beetles are a dominant group of forest insects, which are being used in many projects as indicators of environmental change. Many species are forest specialists restricted to certain microhabitats, some are generalists and others are open habitat specialists. They represent many ecological niches and, as such, are good indicators for many other species as well. The majority of Canadian aleocharine beetle species (about 600 spp.) has been studied and published by Jan Klimaszewski et al. (2018, 2020), mainly from southern, central, and western Canada, while the northern taxa remain poorly known and documented. The aim of the present book is to summarize the knowledge on this insect group in the Arctic and Subarctic North America and to provide a diagnostic and ecological tool for scientists studying and monitoring insects in northern Canada and Alaska. The book includes a review of the literature, information on 238 species and their habitats, taxonomic review, images, and identification tools.
    Type of Medium: Online Resource
    Pages: XIV, 712 p. 315 illus., 307 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030681913
    DDC: 590
    Language: English
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  • 69
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Reproductive health. ; Cytology. ; Biomedical Research. ; Reproductive Medicine. ; Cell Biology.
    Description / Table of Contents: Ch 1: The seminiferous epithelial cycle of spermatogenesis: Role of non-receptor protein kinases -- Ch 2: Sertoli cells: immunology and spermatogenesis -- Ch 3: Innate immunity and spermatogenesis -- Ch 4: Cell apoptosis and spermatogenesis -- Ch 5: Transcriptional regulation of spermatogenesis -- Ch 6: Sertoli cell cytoskeleton and spermatogenesis -- Ch 7: Leydig cell and spermatogenesis -- Ch 8: Cross-talk of cell junctions to support spermatogenesis -- Ch 9: Coordination of F-actin- and MT-based cytoskeletons to support spermatogenesis -- Ch 10: Regulation of the blood-testis barrier by basement membrane laminin-α2 chain -- Ch 11: Regulation of spermatogenesis by collagens -- Ch 12: Androgen regulation of spermatogenesis -- Ch 13: Use of molecular modeling to study spermatogenesis -- Ch 14: Acrosome biogenesis during spermatogenesis -- Ch 15: Stem cells and spermatogenesis -- Ch 16: Advances in our understanding of spermatogenesis in humans -- Ch 17: Leydig cell function in aging men -- Ch 18: Regulation of human spermatogenesis.
    Abstract: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.
    Type of Medium: Online Resource
    Pages: X, 319 p. 44 illus., 40 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030777791
    Series Statement: Advances in Experimental Medicine and Biology, 1381
    DDC: 610.72
    Language: English
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  • 70
    Keywords: Botany. ; Plant biotechnology. ; Plant cells and tissues. ; Plant Science. ; Plant Biotechnology. ; Plant Cell Biology.
    Description / Table of Contents: Bamboo: origin, habitat, distributions and global prospective -- Molecular markers in bamboos: understanding reproductive biology, genetic structure, interspecies diversity and clonal fidelity for conservation and breeding -- Standard protocols for in vitro propagation of bamboo with emphasis on axillary shoot proliferation -- Somatic embryogenesis in bamboos: advances and prospects -- Initiation and establishment of cell suspension culture in bamboo -- Micro-morpho-anatomical alterations in micropropagated plants of endrocalamus strictus -- Micropropagation of bamboos and clonal fidelity assessment using molecular markers -- Standardization of laboratory to land transfer strategies of micropropagated plantlets of bamboo -- Management of bamboo genetic resources and clonal production systems -- Polymorphism and phylogenetic relationships in bamboo -- Transgenics approaches in Bamboo -- Advances in Conservation of Bamboo Genetic Resources through Whole Seeds Cryopreservation -- Application of Biotechnological Tool in Bamboo Improvement -- Ethnobamboology: traditional uses of bamboos and opportunities to exploit genomic resources for better exploitation -- Bamboo flowering in South America: what the past tells about the future -- Molecular Markers in Bamboo Genotyping: Prospects for Conservation and Breeding -- Application of bamboo in the food and pharmaceutical industry -- Functional pasta: a comparative study of the use of bamboo shoot fiber and white fibers -- Bamboo fiber as a substitute for fat and/or sugar in cookies -- Practical application of bamboo as a building material: trends and challenges.
    Abstract: “Green gold” or “Poor Man’s Timber” are commonly used terms for bamboo that is a valuable and renewable resource of the world, and has always been an elemental part of human beings in terms of social and economic value. Bamboo is considered a multipurpose plant and has a prolonged history as an adaptable and extensively used renewable resource in conventional and commercial applications. Therefore, the annual demands for bamboos have already out-crossed the annual yields across the world. And the current scenario has forced scientists to pay more attention to the utilization of biotechnological tools for better understanding and improving bamboos. The book provides an overview of the different biotechnological approaches to advance bamboo research and better utilization of bamboo resources for human beings. Various applications of biological techniques in relation to bamboo have been discussed in details, for example, plant tissue culture techniques, somatic embryogenesis, germplasm conservation techniques, use of the molecular markers, transcriptomics, polymorphism, and phylogenetic relations in bamboo. It also addresses the novel industrial applications of bamboo in structural, food, and pharmaceuticals along with traditional uses. The aggregated information in this book demonstrates the way for the improved and sustainable practice of bamboos to fulfill the future needs of the world. This book is intended for use in both the industry and academia.
    Type of Medium: Online Resource
    Pages: XV, 481 p. 82 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811613104
    DDC: 580
    Language: English
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  • 71
    Keywords: Food science. ; Food Analysis. ; Chemistry. ; Nutrition   . ; Food Safety measures. ; Food Science. ; Food Chemistry. ; Nutrition. ; Food Safety.
    Description / Table of Contents: Chapter 1 Introduction -- Chapter 2.Global Scenario of Coconut and Coconut Water -- Chapter 3 Tender Coconut Varieties -- 4 Composition, Properties and Reactions of Coconut Water -- Chapter 5 Processing of Coconut Water -- Chapter 6 Packing, Storage and Transport of Coconut Water -- Chapter 7 Standards of Coconut Water -- Chapter 8 Value addition in Coconut Water -- Chapter 9 Health Benefits of Coconut Water -- Chapter 10 Contamination and Adulteration of Coconut Water -- Chapter 11 Patents Granted on Coconut Water -- Chapter 12 Coconut Water- The Way Forward.
    Abstract: Coconut water, a naturally-canned tropical beverage, has been gaining popularity in recent years and has drawn the attention world over as a natural and nutritional wellness beverage. The research published thus far on coconut water has mainly focused on its specific uses, biochemical composition and health benefits as well as processing and preservation techniques and has been published mostly in journal articles. Only a few books covering a wide spectrum of coconut water for health and wellness are currently available. This work offers a comprehensive and fully updated overview of coconut water from processing techniques to value addition to safety to nutritional benefits and beyond. Coconut Water: Processing, Distribution & Nutritional Benefits provides in-depth details on all of the major processing techniques required to produce and maintain a quality product free of contamination and adulteration. The book covers the standards of coconut water production and distribution in various countries enabling the processors and exporters to manufacture and export for better revenue realization. The book also provides details of patents related to coconut water granted to researchers. Another important aspect of this work is comprehensive coverage on the various nutritional and health benefits of coconut water consumption as well as on the value addition (traditional and innovative products). In markets across the world, consumers of all ages have been turning to coconut water for its taste and nutritional benefits. This book will provide researchers, processors and exporters the comprehensive information needed to produce and market quality, nutritional coconut water for consumers. .
    Type of Medium: Online Resource
    Pages: XXXV, 507 p. 57 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031107139
    DDC: 641.3
    Language: English
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  • 72
    Keywords: Medical sciences. ; Ethics. ; Medical education. ; Social sciences. ; Humanities. ; Health Sciences. ; Moral Philosophy and Applied Ethics. ; Medical Education. ; Humanities and Social Sciences.
    Description / Table of Contents: Part 1: Defining Medical Professionalism -- Chapter 1. Professionalism and Medical Practice – Introduction (Luis Vivanco) -- Chapter 2. Medical Professionalism – A Developmental View from the Trenches (Renzo Pegoraro) -- Chapter 3. The Need for a Common Set of Competencies as Ingredients for Medical Professionalism, Paired with a Common Program of Assessment (Aaron R. Douglas) -- Part 2: Medical Professionalism from Broader Perspectives -- Chapter 4. Medical Professionalism – legal framework (Sunčana Roksandić) -- Chapter 5. Medical Professionalism – Sociological Framework (Gordana Cerjan Letica) -- Part 3: The Moral Foundations of Medical Professionalism -- Chapter 6. Medical Professionalism – Philosophical Framework (Marko Ćurković) -- Chapter 7. Medical Professionalism from Virtue Ethics Perspective (Claudia Ruiz Sotomayor) -- Part 4. Medical Professionalism – Interpersonal Views and Considerations -- Chapter 8. Interpersonal or Relational Professionalism (Marko Ćurković) -- Chapter 9. The Physician Patient Relationship: a Philosophical Perspective on Medical Professionalism and Virtues (Roberto Dell’Oro) -- Chapter 10. Physicians Towards Fellow Colleagues (Marko Ćurković) -- Chapter 11. Physicians Towards Other Healthcare Professionals (and Vice Versa) (Marko Ćurković) -- Chapter 12. Interdisciplinary Challenges to Interprofessional Practice (Jos V. M. Welie) -- Part 5. Medical Professionalism – Unique Challenges and Duties -- Chapter 13. The Impact of Uncertainties on Physicians’ Health and Wellbeing (Marko Ćurković) -- Chapter 14. Physicians and Organization: For a Reflective Organizational Professionalism (Jean-Philippe Cobbaut) -- Chapter 15. Victims or Actors? Can Professionalism Shape Physicians’ Roles Inside the Health Care System? (Bernice Elger) -- Chapter 16. What do Doctors and Society Owe Each Other? A Scanlonian Reflection on Medical Professionalism (Andrew Papanikitas) -- Chapter 17. Physicians Towards Society (and Vice Versa) (Sabine Salloch) -- Part 6: Medical Professionalism Across Contemporary and Cultural Landscapes -- Chapter 18. Professionalism and Medical Practice - Cultural Perspectives (Marko Ćurković) -- Chapter 19. Physicians as Citizens of the World (Henk ten Have) -- Chapter 20. Physicians as Agents in Evolving Knowledge Landscapes (Srećko Gajović) -- Chapter 21. Afterthoughts: Towards a Realpolitik of Professionalism (Nathan Emmerich).
    Abstract: This book provides insights into dynamic and complex interrelationships between professionalism and medical practice. It does so by looking into the most relevant and recent theoretical and practical frameworks and by systematizing and integrating extensive and growing literature on medical professionalism. Through honest and prudent contributions from very diverse backgrounds and contexts, this book provides an understanding of medical professionalism derived from a broader historical and cultural context in order to contribute to everyday professional life and practice – the very place of its existence. The book presents the conflicting and sometimes irreconcilable demands and challenges physicians face in everyday practice. A better understanding of these fundamental issues is the only way for medicine to maintain and preserve its unique morality, the same one that enabled its existence in the first place. The book is relevant for everyone immersed and interested in the subject of medical professionalism as a resource, which may ease or guide them through the complexities of issues at hand. It will also contribute to the ongoing debate on medical professionalism, medical ethics, bioethics, and professionalism and ethics in general.
    Type of Medium: Online Resource
    Pages: XXI, 493 p. 59 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031097331
    Series Statement: The International Library of Bioethics, 98
    DDC: 610
    Language: English
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  • 73
    Keywords: Biomaterials. ; Nanotechnology. ; Biomedical engineering. ; Polymers. ; Microfluidics. ; Biomaterials. ; Nanotechnology. ; Biomedical Engineering and Bioengineering. ; Biomedical Materials. ; Polymers. ; Microfluidics.
    Description / Table of Contents: Introduction to high resolution manufacturing from 2D to 3D/4D printing -- Technologies evolutions and Design Considerations -- Vat photopolymerization -- Stereolithography -- Digital Light Processing -- Continuous liquid interface production -- Materials -- Multi-photon polymerization -- 2PP -- Materials -- Powder bed fusion -- Selective Laser Sintering -- Materials -- Commodity Polymers -- Engineering Polymers -- High-Performance Polymers -- Thermoplastic Elastomers -- The role of fillers -- Ink-jet printing -- Polyjet printing -- Aerosol jet printing -- Materials -- Volumetric 3D printing -- Computed Axial Lithography -- Xolography -- Materials -- Impact on different research fields and case studies -- Biomedical applications -- Cells culture, Microfluidics, rapid diagnostic tools -- Electronic applications -- Sensors and biosensors, actuators, integrated circuits -- Energy applications -- Supercapacitors, Energy harvesting -- Photonic applications -- Woodpile structures, light guides, optical fiber -- Future outlook.
    Abstract: This book provides a comprehensive presentation of the most frequently used high resolution manufacturing techniques available, as well as the polymeric materials used for each of the techniques. Divided into two parts covering the technologies and materials used and the impact on different research fields and case studies, High Resolution Manufacturing from 2D to 3D/4D Printing: Applications in Engineering and Medicine addresses issues like throughput improvement by volumetric 3D printing and presenting novel applications and case studies. In addition, this book also covers the latest breakthrough developments and innovations to help readers understand the future applications of this technology across various disciplines, including biomedicine, electronics, energy, and photonics.
    Type of Medium: Online Resource
    Pages: X, 300 p. 128 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031137792
    DDC: 620.19
    Language: English
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  • 74
    Keywords: Agriculture. ; Soil science. ; Plant biotechnology. ; Agronomy. ; Stress (Physiology). ; Plants. ; Plant diseases. ; Agriculture. ; Soil Science. ; Plant Biotechnology. ; Agronomy. ; Plant Stress Responses. ; Plant Pathology.
    Description / Table of Contents: 1. Soybean: A Key player for global food security -- 2. Dissection of Physiological and Biochemical Bases of Drought tolerance in Soybean (Glycine max) Using recent Phenomics approach -- 3. Soybean Improvement for Water-logging Tolerance -- 4. Salinity tolerance in Soybeans: Physiological, molecular and genetic perspectives -- 5. Utility of Network Biology Approaches to Understand the Aluminium Stress Responses in Soybean -- 6. Advances in Molecular markers to develop Soybean cultivars with increased protein and oil content -- 7. Soybean Breeding for Rust Resistance -- 8. Molecular breeding for resistance against pythium root rot (PRR) in soybean -- 9. Molecular Breeding for Resistance against Phytophthora in Soybean -- 10. Mitigation of Soybean Mosaic Virus Using an Efficient Molecular Approach -- 11. Transgenic Approach: A Key to Enrich Soybean Oil Quality -- 12. miRNAs in soybean improvement -- 13. Genome Editing Advances in Soybean Improvement against Biotic and Abiotic stresses.
    Abstract: Soybean (Glycine max L. (Merr)) is one of the most important crops worldwide. Soybean seeds are vital for both protein meal and vegetable oil. Soybean was domesticated in China, and since last 4-5 decades it has become one of the most widely grown crops around the globe. The crop is grown on an anticipated 6% of the world’s arable land, and since the 1970s, the area in soybean production has the highest percentage increase compared to any other major crop. It is a major crop in the United States, Brazil, China and Argentina and important in many other countries. The cultivated soybean has one wild annual relative, G. soja, and 23 wild perennial relatives. Soybean has spread to many Asian countries two to three thousand years ago, but was not known in the West until the 18th century. Among the various constraints responsible for decrease in soybean yields are the biotic and abiotic stresses which have recently increased as a result of changing climatic scenarios at global level. A lot of work has been done for cultivar development and germplasm enhancement through conventional plant breeding. This has resulted in development of numerous high yielding and climate resilient soybean varieties. Despite of this development, plant breeding is long-term by nature, resource dependent and climate dependent. Due to the advancement in genomics and phenomics, significant insights have been gained in the identification of genes for yield improvement, tolerance to biotic and abiotic stress and increased quality parameters in soybean. Molecular breeding has become routine and with the advent of next generation sequencing technologies resulting in SNP based molecular markers, soybean improvement has taken a new dimension and resulted in mapping of genes for various traits that include disease resistance, insect resistance, high oil content and improved yield. This book includes chapters from renowned potential soybean scientists to discuss the latest updates on soybean molecular and genetic perspectives to elucidate the complex mechanisms to develop biotic and abiotic stress resilience in soybean. Recent studies on the improvement of oil quality and yield in soybean have also been incorporated.
    Type of Medium: Online Resource
    Pages: VIII, 276 p. 37 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031122323
    DDC: 630
    Language: English
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  • 75
    Keywords: Agricultural biotechnology. ; Subsistence farming. ; Agricultural genome mapping. ; Agricultural Biotechnology. ; Subsistence Agriculture. ; Agricultural Genetics.
    Description / Table of Contents: Chapter 1. Evolution of the Knowledge and Practice of Endophytic Microorganisms for Enhanced Agricultural Benefit and Environmental Sustainability -- Chapter 2. The Mycorrhizosphere Revisited – Multitrophic Interactions -- Chapter 3. Conservation Strategies for Rhizobiome in Sustainable Agriculture -- Chapter 4. Exploring the rhizosphere microbiome for sustainable agriculture production -- Chapter 5. From Rhizosphere to Endosphere: Bacterial-Plant Symbiosis and its impact on Sustainable Agriculture -- Chapter 6. Arbuscular Mycorrhizal fungal symbiosis for mutual benefit: More than expectation -- Chapter 7. Rhizodeposits- An essential component for microbial interactions in rhizosphere -- Chapter 8. Rhizospheric Microbial Diversity: Organic Vs. Inorganic Farming System -- Chapter 9. Rhizomicrobes: The underground life for sustainable agriculture -- Chapter 10. Synthetic biology tools in cyanobacterial biotechnology: recent developments and opportunities -- Chapter 11. The potential of rhizobacteria for plant growth and stress adaptation -- Chapter 12. Mycoremediation – An emerging technology for mitigating environmental contaminants -- Chapter 13. Exploration of Plant growth-promoting rhizobacteria (PGPR) for improving productivity and soil fertility under sustainable agricultural practices -- Chapter 14. Rhizosphere engineering for systemic resistance/tolerance to biotic and abiotic stress -- Chapter 15. Understanding the Microbiome Interactions across the Cropping System -- Chapter 16. Role of rhizosphere microorganisms in endorsing overall plant growth and development -- Chapter 17. Rhizospheric microbial community as drivers of soil ecosystem: Interactive microbial communication and its impact on plants -- Chapter 18. Rhizospheric Microbes and Plant Health -- Chapter 19. Omics approaches to unravel the features of rhizospheric microbiome -- Chapter 20. Rhizo-deposit and their role in rhizosphere interactions among the plant, microbe and other ecological components for crop management -- Chapter 21. Effects of Irrigation with Municipal Wastewater on the Microbiome of the Rhizosphere of Agricultural Lands -- Chapter 22. Plant-Rhizosphereic microbes interactions: enhancing plant growth and improving soil biota -- Chapter 23. Microbes mediated rhizospheric engineering for salinity stress mitigation -- Chapter 24. Metatranscriptomics of plant rhizosphere: A promising tool to decipher the role of microorganisms in plant growth and development -- Chapter 25. Rhizospheric engineering for sustainable production of horticultural crops.
    Abstract: The present book entitled, “Re-visiting the Rhizosphere Eco-system for Agricultural Sustainability” written by experts in the field, provides a comprehensive and consolidated state-of art overview of various aspects of rhizosphere biology, ecology and functioning. The role of rhizosphere microbial diversity in enhancing plant health and plant-microbe beneficial symbioses is discussed. Main topics include the diversity of plant-associated microbes in the rhizosphere, below-ground communication among the plant, soil, insects and microbes, rhizosphere ecosystem functioning, rhizosphere engineering, recruitment of microorganisms in the rhizosphere, mycorrhizal fungal symbiosis, positive interaction of the plants with the beneficial soil microorganisms for inducing the plant growth, conferring abiotic and biotic stress tolerance and modulating several pathways of the plants for the proper establishment and revitalization in the degraded and contaminated soils or negative likes the host-pathogen interactions leading to the disease development in plants. Further chapters focus on the role of signaling during the different stages of the plant-microbe coexistence, in symbiotic or pathogenic relationships, in quorum sensing, microbial signaling and cross-talk, bio-film formation, and antimicrobial peptides. The book also discusses the application of microbes in biodegradation of xenobiotic contaminants, bioremediation of heavy metals, sustainable agriculture and soil health, biological control of insect pests and plant pathogens, and the latest tools of omics which offer pioneering approaches to the exploration of microbial structure and function, secretome, holobiome, below-ground interaction, and microbial cooperation for sustainable food production and enhanced resource acquisition. Descriptions of cutting-edge techniques and novel approaches make this book unique in the area of rhizosphere biology. This is a useful reading material for researchers and students of microbiology, agriculture, ecology, and rhizosphser studies.
    Type of Medium: Online Resource
    Pages: XXI, 537 p. 37 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811941016
    Series Statement: Rhizosphere Biology,
    DDC: 630
    Language: English
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  • 76
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botany. ; Agriculture. ; Plant molecular biology. ; Botanical chemistry. ; Plant Science. ; Agriculture. ; Plant Molecular Biology. ; Plant Biochemistry.
    Description / Table of Contents: Chapter 1. Plant Metal and Metalloid Transport -- Chapter 2. Heavy Metals: Transport in Plants and their Physiological and Toxicological Effects -- Chapter 3. The Role of ABC Transporter in Metal Tranasport in Plants -- Chapter 4. Cadmium, A Non-Essential Heavy Metal: Uptake, Translocation, Signaling, Detoxification, and Impact on Amino Acid Metabolism -- Chapter 5. Natural Resistance Associated Macrophage Proteins (NRAMP): Functional Significant of Metal Transport in Plants -- Chapter 6. Role of Heavy Metal Atpases in Transport of Cadmium and Zinc in Plants -- Chapter 7. The Versatile Role of Plant Aquaglyceroporins in Metalloid Transport -- Chapter 8. The Multidrug and Toxic Compound Extrusion (MATE) Family in Plants and Their Significance in Metal Transport -- Chapter 9. Molecular Mechanism of Aluminium Tolerance in Plants: An Overview -- Chapter 10. Functional, Structural, and Transport Aspects of ZIP in Plant -- Chapter 11. The Function of HAK as K+ Transporter and AKT as Inward Rectifying Agent in The K+ Channel -- Chapter 12. The Mechanism of Silicon Transport in Plants -- Chapter 13. The Copper Transport Mechanism in Plants -- Chapter 14. Plant Metal Tolerance Proteins: Insight Into their Roles in Metal Transport and Homeostasis for Future Biotechnological Applications -- Chapter 15. Co-Transport Mechanism in Plants for Metals and Metalloids -- Chapter 16. Metal Nanoparticles Implication, Transport, and Detection in Plants -- Chapter 17. Transcription Factors and Metal Stress Signalling in Plants -- Chapter 18. Heavy Metal Transporters, Phytoremediation Potential and Biofortification -- Chapter 19. Phytoremediation and Biofortification: Contrasting Yet Similar Approaches of Manipulating Plant Metal(Loid) Homeostasis for Societal Benefit.
    Abstract: This edited book stands as a one place knowledge hub for plant metal(loid) transporters. The book comprehensively covers holistic aspect of metal(loid) transporters involved in uptake and translocation of essential as well as toxic metal(loid)s. Essential and beneficial metal(loid)s are required in every biological process for normal plant growth and development, however in excess they are toxic. There are toxic metal(loid)s also whose accumulation in plants interferes with normal cellular functioning and hampers growth of plants. Hence, metal(loid) uptake and accumulation in plants is a highly regulated phenomenon involving the role of several transporters, enzymes, metabolites, transcription factors and post translational modifications. The book contains chapters from the experts and the contents of the book are presented in simple language and represented through beautiful and scientifically informative figures and tables. This book is of interest to teachers, researchers, doctoral and graduate students working in the area of plant physiology, environmental biotechnology, plant biotechnology metal(loid) stress, phytoremediation and crop biofortification.
    Type of Medium: Online Resource
    Pages: XIII, 454 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811961038
    DDC: 580
    Language: English
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  • 77
    Keywords: Veterinary medicine. ; Medicine Research. ; Biology Research. ; Biometry. ; Veterinary Science. ; Biomedical Research. ; Biostatistics.
    Description / Table of Contents: An introduction to reproducibility in the context of animal research -- Rodent Genetics -- Animal and environmental factors that influence reproducibility -- Microbiology and Microbiome -- Effects of untreated pain, anesthesia and analgesia in animal experimentation -- Why do we need a statistical experiment design -- Statistical tests and Sample size calculations -- Design of experiments -- Scholarly Publishing and Scientific Reproducibility -- Systematic reviews -- Planning animal experiments.
    Abstract: This highly-readable text provides grounds on how to plan and conduct animal experiments that can be reproduced by others. The book touches on factors that may impact the reproducibility of animal studies including: the animal genetic background, the animal microbial flora, environmental and physiological variables affecting the animal, animal welfare, statistics and experimental design, systematic reviews of animal studies, and the publishing process. The book addresses advanced undergraduates, graduate students and all scientists working with animals.
    Type of Medium: Online Resource
    Pages: VI, 277 p. 52 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030661472
    Series Statement: Laboratory Animal Science and Medicine, 1
    DDC: 636.089
    Language: English
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  • 78
    Keywords: Biotechnology. ; Microbiology. ; Plant diseases. ; Microbial ecology. ; Biotechnology. ; Microbiology. ; Plant Pathology. ; Microbial Ecology.
    Description / Table of Contents: Bacterial Endophytes: Diversity, Functional Importance, and Potential for Manipulation -- Rhizosphere Carbon Turnover from Cradle to Grave: The Role of Microbe–Plant Interactions -- Root–Soil–Microbe Interactions Mediating Nutrient Fluxes in the Rhizosphere -- Diazotrophic Nitrogen Fixation in the Rhizosphere and Endosphere -- Root Microbiome Structure and Microbial Succession in the Rhizosphere -- Rhizosphere Legacy: Plant Root Interactions with the Soil and Its Biome -- Rhizosphere Microbiome and Soil-Borne Diseases -- Root Disease Impacts on Root-Rhizosphere Microbial Communities -- Newly Introduced or Modified Genes in Plants Potentially Modulate the Host Microbiome -- Rhizosphere Plant–Microbe Interactions Under Abiotic Stress -- Arbuscular Mycorrhizal Fungi Interactions in the Rhizosphere -- Microbial–Faunal Interactions in the Rhizosphere -- Inter-Organismal Signaling in the Rhizosphere -- Molecular Mechanisms of Plant–Microbe Interactions in the Rhizosphere as Targets for Improving Plant Productivity -- Inoculation Effects in the Rhizosphere: Diversity and Function.
    Abstract: This book presents a detailed discussion on the direct interactions of plants and microorganisms in the rhizosphere environment. It includes fifteen chapters, each focusing on a specific component of plant-microbe interactions, such as the influence of plants on the root microbiome, and the downstream effects of rhizosphere microbial dynamics on carbon and nutrient fluxes in the surroundings. As such, the book helps readers gain a better understanding of diversity above the ground, and its effect on the microbiome and its functionality.
    Type of Medium: Online Resource
    Pages: XVIII, 356 p. 36 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811561252
    Series Statement: Rhizosphere Biology,
    DDC: 660.6
    Language: English
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  • 79
    Keywords: Biotechnology. ; Medicine Research. ; Biology Research. ; Entrepreneurship. ; New business enterprises. ; Public health. ; Biotechnology. ; Biomedical Research. ; Entrepreneurship. ; Public Health.
    Description / Table of Contents: Part I. What Is Wrong with Health? What Should the Future of Health Be? -- INNOVATION DESIGN for the FUTURE of HEALTH -- Health Innovations from an Innovators’ Perspective -- From SICKCARE to HEALTHCARE to HEALTH -- Future Look on Health: Opportunities -- Navigating Towards a Future of “One Health” -- Part II. Exponential Medicine + Technologies + Mindset -- Exponential Technologies for an Exponential Medicine -- Exponential Medicine: Challenges of Human Spaceflight Bringing Innovations for Earth—A Case Study -- Healthy Longevity -- The Science of Health Longevity -- Space Healthtech: Innovation Base for Longevity -- Part III. Future Health Value Propositions -- Healthcare the Melting Pot of Technology, Humanity, and Confusion -- Democratize Health Delivery -- Health Innovation Process: Definitions and Short Methodology Introductions -- Prevention, Prediction, Personalization, and Participation as Key Components in Future Health -- Digital Health Business Models: Transformation Is on the Horizon -- Value Propositions for Future Health Developments: Digital, Portable, Connected, Experience-Enhancing, Supportive, Patient-Centric, and Affordable -- (Digital) Patient Journey and Empowerment: Digital Twin -- Part IV. Innovation Methodology Basics -- Stanford Biodesign as Base: Empathy and Patient Centricity as the Main Driver -- Purpose Launchpad Methodology: Introduction -- Design Thinking for Innovations in Healthcare -- VPC to BMC to Exponential Canvas: Canvas Interconnectivity for Exponential Scaling -- Innovation Methodology I3 EME: Awareness for Biomedical Engineers -- Part V. Ethics + Health Innovation -- Integrating Ethical Considerations into Innovation Design -- Part VI. Health Innovation Design -- Case Studies Used Throughout the Book: Innovation Categories Explained -- Why Is Healthcare Different with Respect to Innovation and Entrepreneurial Activities? -- Purpose Launchpad Health (PLH) Methodology Introduction -- Part VII. Purpose Launchpad Health -- Purpose Launchpad Health: Exploration and Evaluation Phases—Actual Case Studies -- Part VIII. Health Leadership, Skills and other Methodologies -- Soft Skills Needed for Problem Understanding and Innovation Generation -- Leadership in Healthcare: A Novel Approach. Healthcare Executives’ Traits, Styles, and Approaches -- Future Skills Framework in Healthcare -- Porter’s Five Forces Analysis: Quo Vadis Immunotherapy Industry -- Part IX. Health Entrepreneurship -- Global Health Markets and Their Different Needs -- Patient: Health Relation and Digital Health Entrepreneurship -- Health Start-Up: Create Impact and be Investment Ready Intra- and Entre-Preneurs -- Regulatory Issues for Health Innovations -- Innovation Think Tank Frameworks for Resolving “The Innovator’s Dilemma” in Healthcare -- A Primer on Patents and IP for Health Innovations -- Successfully Implementing Ambidexterity in the Medical Industry -- Reverse Innovation: Circumvent Digital Health Transformation Issues -- Part X. Health Innovation Education and Incubation -- Health Innovation Design: “CAMPing” for the Unmet Clinical Need -- Health Technology Innovation Generation (HTIG) Lecture and Project Classes at AGH University -- Health Innovation Design at a University: INKA INNOLAB at Otto-von-Guericke-University -- Clinical Innovation at Acibadem Biodesign Center -- Example of a Needs-Driven Innovation Training Program: The BioMedical Design Novo Nordisk Foundation Fellowship Program -- Addressing the Healthcare Needs with Innovation Think Tank Global Infrastructure and its Methodology -- The Power of a Collaborative Ecosystem: Introducing the Edison™ Accelerator -- HealthTec Networks and Clusters (Global): Innovation Clusters in Medtech in Europe -- Leadership-Compass: “Networking and Synapting Empowered by Health Captains” -- Part XI. Purpose Launchpad Health: Toolset Templates and Principles -- PLH Templates and Principles.
    Abstract: This book highlights the reasons for an urgently needed revision of the current global healthcare setup, discusses the needed mindset for a future of health, and provides a comprehensive development toolset for disruption (and for the needed incremental innovations towards disruption). Today’s biomedical and health innovation related research in universities encourages activities that lead to incremental innovations with a relatively low risk of failure. The healthcare industry on the other hand provides tools and devices for established healthcare providers to improve the diagnosis and therapy/ treatment of the patients’ health problems. The patient is not in the center of healthcare provision however, and prevention and prediction are not core goals. The current health setup needs to be challenged and disrupted. Disruptions are coming from technologies or processes that lead to a significant (〉10x) reduction in cost or price/ performance and that also come with new business models. The need for change, effects of exponential technologies, and the needed shift to prevention and to homecare for health democratization and patient empowerment will be discussed in detail in the first parts of the book. The subsequent sections address several innovation methods with a focus on a novel meta methodology named Purpose Launchpad Health. This is followed by a comprehensive discussion on health entrepreneurship activities and needs. The final section of the book addresses how to train students to become entrepreneurial health innovators, presenting successful curricula and examples of health incubation and accelerator setups. All of the innovation tools presented and used in this book are summarized in the final chapter to help the reader get started planning an entrepreneurial venture. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments. Chapters are concise and enriched with key messages, learning objectives and real innovation examples to bridge theory and practice. This book aims to serve as a teaching base for health innovation design and to prepare for health-related entrepreneurial ventures. Readers with medical, biomedical, biotechnology, and health economics backgrounds - and anyone who wants to become a future oriented health innovator or who believes in disruptive approaches - will find this book a useful resource and teaching tool for developing validated products/ services and processes for the future of health.
    Type of Medium: Online Resource
    Pages: XXXIV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031081910
    DDC: 660.6
    Language: English
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  • 80
    Keywords: Plant genetics. ; Plant biotechnology. ; Botanical chemistry. ; Plant physiology. ; Agriculture. ; Biomaterials. ; Nucleic acids. ; Plant Genetics. ; Plant Biotechnology. ; Plant Biochemistry. ; Plant Physiology. ; Agriculture. ; Nucleic Acid.
    Description / Table of Contents: Chapter 1.Genetic tinkering of crops for sustainable development – 2020 and Beyond -- Chapter 2.Genetic improvement of rice for food and nutritional security 3.Improvement of wheat (Triticum spp.) through gene manipulation -- Chapter 4. Transgenic finger millet [Eleusine coracana (L.) Gaertn.] for crop improvement -- Chapter 5. Transgenic pigeon pea [Cajanus cajan (L). Millsp.] -- Chapter 6. Genetically engineered chickpea: Potential of an orphan legume to achieve food and nutritional security by 2050 -- Chapter 7. Progress in genetic engineering of cowpea for insect pest and virus resistance -- Chapter 8. Peanut (Arachis hypogaea L.) transgenic plants for abiotic stress tolerance -- Chapter 9. Genetic engineering of sunflower (Helianthus annuus L.) for important agronomic traits -- Chapter 10. Genetic engineering in safflower (Carthamus tinctorius L.): Retrospect and prospect -- Chapter 11. Nutritional value, in vitro regeneration and development of transgenic Cucurbita pepo and C. maxima for stress tolerance: An overview -- Chapter 12. Sugarcane transgenics: Developments and opportunities .
    Abstract: Genetic transformation is a key technology, in which genes are transferred from one organism to another in order to improve agronomic traits and ultimately help humans. However, there is apprehension in some quarters that genetically modified crops may disturb the ecosystem. A number of non-governmental organizations continue to protest against GM crops and foods, despite the fact that many organisms are genetically modified naturally in the course of evolution. In this context, there is a need to educate the public about the importance of GM crops in terms of food and nutritional security. This book provides an overview of various crop plants where genetic transformation has been successfully implemented to improve their agronomically useful traits. It includes information on the gene(s) transferred, the method of gene transfer and the beneficial effects of these gene transfers and agronomic improvements compared to the wild plants. Further, it discusses the commercial prospects of these GM crops as well as the associated challenges. Given its scope, this book is a valuable resource for agricultural and horticultural scientists/experts wanting to explain to the public, politicians and non-governmental organizations the details of GM crops and how they can improve crops and the lives of farmers.
    Type of Medium: Online Resource
    Pages: XIII, 265 p. 14 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811558979
    DDC: 581.35
    Language: English
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  • 81
    Keywords: Botany. ; Nutrition   . ; Medicinal chemistry. ; Food science. ; Plant Science. ; Nutrition. ; Medicinal Chemistry. ; Food Science.
    Description / Table of Contents: Foreword -- Preface -- Wetlands and Wetland Plants -- Climate of Wetlands -- Types of Wetlands and Wetland Plants -- Importance of Biodiversity in Wetlands -- Nutritive Value of Wetland Flora -- Medicinally Important Wetland Flora -- Threats to Biodiversity of Wetlands -- Conservation Strategies of Wetland Flora -- Wetland Plants of Himalayas: A case study -- A Pictorial Guide to Wetland plants of Himalayas -- Bibliography.
    Abstract: Due to their high nutritive value and the presence of secondary metabolites, wetland plants can be consumed by humans as food and utilized as medicinal drugs. Significant numbers of ethno-botanic resources have been reported to extract useful compounds, which can be used as pharmaceuticals. Wetland plants are also very valuable as an energy source, as fuel for fish smoking and for domestic energy. These plants can be harvested as wild stock, or cultivated in flooded paddies for aquaculture, food and for livestock fodder. All parts of plants can be utilized for foodstuff, compost, mulch, medicine, and for construction. Wetland Plants: A Source of Nutrition and Ethnomedicine aims to promote public understanding of this remarkable resource, exploring not only their role in the ecosystem but also their nutritional and medicinal purposes. Based on original research, the text focuses on species identification (with original pictures of wetland plants including morphological features), nutritive value and ethno-medicinal uses. This book serves as an important and basic reference material for further research into the basic biological as well as the applied medicinal aspects of traditional medicinal wetland plants.
    Type of Medium: Online Resource
    Pages: XXIX, 228 p. 149 illus., 148 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030692582
    DDC: 580
    Language: English
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  • 82
    Keywords: Food science. ; Business Data processing. ; Bioinformatics. ; Food Engineering. ; Business Informatics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1 - Poultry and Egg Production: An Overview -- Chapter 2 - Egg formation and Embryonic Development: An Overview -- Chapter 3 - Chemometric for Spectroscopy-Based Poultry and Egg Research -- Part-I: Table Eggs -- Chapter 4 - Non-destructive Quality Assessment of Table Eggs for Online Sorting -- Part-II: Hatching Eggs -- Chapter 5 - Grading of Hatching Eggs -- Chapter 6 - Non-destructive Technologies for Embryo Gender Prediction -- Chapter 7 - Hatch Window Monitoring, Control and Management -- Chapter 8 -: Chick Embryo Grading: A Future Tool for Precision Poultry Production -- Chapter 9 - A Vision for Smart Poultry Production to Achieve Multiple SDGs.
    Abstract: This book discusses table and hatching eggs, quality-based grading of eggs, pre-incubation, incubation, hatching and post-hatch monitoring period, and how the next-generation management of these process can be enriched by informatics through non-destructive technologies, signal processing, machine learning, AI, IoT applications, etc. This book will be a beneficial resource for egg and poultry science researchers, avian biologists and ecologists, developmental biologists, agricultural engineers, advanced graduate and postgraduate students, and poultry production industry stakeholders.
    Type of Medium: Online Resource
    Pages: XIV, 156 p. 76 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811925566
    DDC: 664
    Language: English
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  • 83
    Keywords: Biotechnology. ; Agriculture. ; Botany. ; Microbiology. ; Biology Technique. ; Biotechnology. ; Agriculture. ; Plant Science. ; Microbiology. ; Biological Techniques.
    Description / Table of Contents: 1.An Introduction to Beta Glucan and Beta Glucanases -- 2.Industrial Applications of Beta Glucanases -- 3.Microbial Sources of Beta Glucanase Enzymes -- 4.Role of Beta Glucanases in Animal Nutrition -- 5.Betaglucanse in Breweries -- 6. Exploitation of Actinobacteria for Beta Glucanolytic enzymes –Screening and Characterisation -- 7.Structural Characterisation of Beta Glucanase Genes from Actinobacteria -- 8.Application of Codon Optimization in Actinobacterial Beta Glucanases -- 9.Actinobacterial Beta Glucanases: Recombinant Expression of in E. coli -- 10.Purification and Properties of Recombinant Beta Glucanases Enzymes -- 11.Fungal Beta Glucanases -- 12.Industrial Production and Characterisation of Beta Glucanases -- 13.Protein Engineering of Beta Glucanase Enzymes -- 14.Biotechnological Avenues in Hybrid Beta Glucanase Enzyme Production.
    Abstract: This book offers an overview of the current knowledge on beta glucanase enzymes derived from actinobacterial source, their structure, functions and industrial applications. It summarizes the exploitation of actinomycetes, assay methods for beta glucanase screening, structural characterisation, genetic engineering, protein engineering, strategies for purification, characterisation and finally how to synthesize a hybrid enzyme of beta glucanases.Enzyme beta glucanases have considerable interest in industrial biotechnology owing to its distinct effect on the hydrolysis of insoluble beta glucan molecules and applications in particular industrial sectors such as food, feed and beverages industries. The beta glucanases are characterized extensively in microorganisms viz. bacteria, fungi and also in plants. A wide varieties of actinobacterial β- glucanases have exclusively active on β-glucan substrates and cleave the mixed linkage β-glucan chains at different points. This is significant for picking precise substrates for the assay of each type of enzymes within this enzyme groups. The well recognized specificity and mechanism of action within the enormous substrates allow to understand that most of them are varied from cellulases, excluding β-1,4-glucanases. The progress in genetic and protein engineering in actinobacterial beta glucanases improves the stability, activity and thermodynamic properties in relation with industrial relevance. This book will be useful for researchers and students engaged in industrial biotechnology, enzyme production, molecular biology, protein engineering and many more.
    Type of Medium: Online Resource
    Pages: X, 195 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811964664
    Series Statement: Interdisciplinary Biotechnological Advances,
    DDC: 660.6
    Language: English
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  • 84
    Keywords: Botany. ; Biochemistry. ; Plant Science. ; Chemical Biology.
    Description / Table of Contents: Chapter 1. An overview of medicinal plants of the Asteraceae family and their impact on human health -- Chapter 2. Artemisia annua L.: Traditional uses, Phytochemistry and Pharmacological activities -- Chapter 3. Artemisia indica Wild.: Ethnobotany, phytochemistry, pharmacological attributes and safety profile -- Chapter 4. Arnica montana L.: Traditional uses, bioactive chemical constituents, and pharmacological activities -- Chapter 5. Aster tataricus L.f.: Ethnomedicinal uses, phytochemistry and pharmacological activities -- Chapter 6.Atractylodes lancea (Thunb.) DC.: Ethnobotany, phytochemistry, pharmacological attributes and safety profile -- Chapter 7. Carthamus tinctorius L.: Traditional uses, phytochemistry and pharmacological activities -- Chapter 8.Chrysanthemum morifolium Ramat.: A Medicinal Plant with Diverse Traditional Uses, Bioactive Constituents, and Pharmacological Activities -- Chapter 9.Crassocephalum crepidioides (Benth.) S.Moore: Traditional uses, chemical constituents and biological activities -- Chapter 10. Dolomiaea costus (Falc.) Kasana & A. K. Pandey: Ethnomedicinal uses, bioactive chemical constituents and Pharmacological activities -- Chapter 11.Eclipta prostata (L.) L.: Traditional use, phytochemistry and pharmacology -- Chapter 12. Helianthus annuus L.: Traditional uses, phytochemistry and pharmacological activities -- Chapter 13. Silybum marianum (L.) Gaertn.: Traditional uses, phytochemistry and pharmacological activities.
    Abstract: This book highlights 12 major plants in the Asteraceae family from the aspects of traditional uses as food and medicine, phytochemistry, and pharmacological activities. Asteraceae is one of the largest family of flowering plants comprising over 1,600 plant genera and 32,000 plant species. Plants belonging to this family have a long history of being used as medicinal plants for the treatment of various diseases. Many of them are also used in the preparation of foods, beverages, and also used in pharmaceutical and cosmetic industries. In addition, plants such as Artemisia annua have played an important role in the discovery of novel drugs. The book summarizes the traditional uses of the plants in the family Asteraceae and their scientific validation, which helps readers understand their relation and impact on human health. It also explains the Phytochemistry of the species and presents the pharmacological activities and mechanisms in detail. Understanding current scientific knowledge will help in the commercialization of products based on these plants and also helps to find the research gaps that should be fulfilled in the future for their optimal use. It also helps in increasing the awareness of the plant species related to conservation, cultivation, and sustainable utilization. This edited volume comprises chapters contributed by experts from around the world. .
    Type of Medium: Online Resource
    Pages: IX, 230 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811960802
    DDC: 580
    Language: English
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  • 85
    Keywords: Evolution (Biology). ; Anatomy. ; Physical anthropology. ; Physiology. ; Ecology . ; Evolutionary Biology. ; Anatomy. ; Physical-Biological Anthropology. ; Animal Physiology. ; Ecology.
    Description / Table of Contents: Introduction -- Clinical and Evolutionary Perspectives on the Primate Foot: A Historical and Contemporary View -- The Primate Ankle and Hindfoot -- The Primate Midfoot and Human Longitudinal Arch -- The Primate Forefoot -- Myology of the Primate Foot -- The Integument and Associated Structures of the Primate Foot -- Experimental Research on Foot Use and Function During Climbing by Primates -- Foot Posture During Quadrupedal Walking in Primates -- Primate Foot Use During Bipedal Walking -- Running in Addition to Walking Helped Shape the Human Foot -- The Feet of Paleogene Primates -- Miocene Ape Feet -- The Early Hominin Foot -- The Feet of Fossil Homo -- Locomotor behavior of the sloth lemurs (Palaeopropithecidae) and the function and anatomy of a foot adapted for suspensory locomotion -- Recent Developments and Future Directions for the Study of Primate Feet.
    Abstract: The human foot is a unique and defining characteristic of our anatomy. While most primates have grasping, prehensile feet, the human foot stands out as a powerful non-grasping propulsive lever that is central to our evolution as adept bipedal walkers and runners. Very few books have compiled and evaluated key research on the primate foot and provided a perspective on what we know and what we still need to know. This book serves as an essential companion to “The Evolution of the Primate Hand” volume, also in the Developments in Primatology series. This book includes chapters written by experts in the field of morphology and mechanics of the primate foot, the role of the foot in different aspects of primate locomotion (including but not limited to human bipedalism), the “hard evidence” of primate foot evolution including fossil foot bones and fossil footprints, and the relevance of our foot’s evolutionary history to modern human foot pathology. This volume addresses three fundamental questions: (1) What makes the human foot so different from that of other primates? (2) How does the anatomy, biomechanics, and ecological context of the foot and foot use differ among primates and why? (3) How did foot anatomy and function change throughout primate and human evolution, and why is this evolutionary history relevant in clinical contexts today? This co-edited volume, provides, for the first time, a comprehensive review and scholarly discussion of the primate foot from multiple perspectives. It is accessible to readers at different levels of inquiry (e.g., undergraduate/graduate students, postdoctoral researchers, other scholars outside of biological anthropology). This volume provides an all-in‐one resource for research on the comparative and functional morphology and evolution of the primate foot.
    Type of Medium: Online Resource
    Pages: XI, 527 p. 104 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031064364
    Series Statement: Developments in Primatology: Progress and Prospects,
    DDC: 576.8
    Language: English
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  • 86
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Forestry. ; Biology. ; Geology. ; Geotechnical engineering. ; Forestry. ; Biological Sciences. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: 1. Remote Sensing for Forest Inventory and Resources Assessment -- 2. Multiple Sensors and Platforms for Biophysical and Biochemical Characterizations of Various Ecosystem Types of Tropical Forests in Malaysia: Advance, Limitation and Opportunity -- 3. A Review on the Use of LiDAR Remote Sensing for Forest Landscape Restoration -- 4. Assessment and Modeling of Forest Biomass and Carbon Stock and Sequestration using Various Remote Sensing Sensor Systems -- 5. Spatial Modeling of Transport and Resources Accessibility for Protecting Forest Ecosystems Against Forest Fires -- 6. Assessment of Forest Aboveground Biomass Estimation from Superview-1 Satellite Image using Machine Learning Approaches -- 7. Floristic Distribution Modelling for Resource Partitioning of Four Native Tree Species in Azad Jammu and Kashmir (AJK), Pakistan using Maxent -- 8. Application of Remote Sensing Vegetation Indices for Forest Cover Assessments -- 9. Rainforest Assessment in Brunei Darussalam through Application of Remote Sensing -- 10. Rubber Trees and Biomass Estimation Using Remote Sensing Technology -- 11. The Use of Landsat TM Imagery for the Application of Rubber Tree Area and Stand Volume Predictive Models in Rubber Plantations in Selangor, Malaysia -- 12. Using Historical Disturbance Identified with LandTrendr in Google Earth Engine for Land Cover Mapping of Oil Palm Landscapes -- 13. Geospatial Technology - Unlocking the Management and Monitoring in Malaysian Mangrove Forests -- 14. Effect of Tidal Regime, Relative Sea Level and Wind Intensity on Changes of Mangrove Area using Remote Sensing Approach -- 15. Spatio-temporal Distribution of Mangrove at Kuala Sepetang Forest Reserve, Malaysia using Remotely-sensed Data -- 16. Determination of The Effect of Urban Forests and Other Green Areas on Surface Temperature in Antalya -- 17. Conceptualising the Citizen-Driven Urban Forest Framework to Improve Local Climate Condition: Geospatial Data Fusion and Numerical Simulation -- 18. State-of-the-Art on Airborne LiDAR Applications in the Field of Forest Engineering -- 19. Restoration of Damaged Forest and Roles of Remote Sensing -- 20. Recent Advances in UAV-based Structure-from-motion Photogrammetry for Aboveground Biomass and Carbon Storage Estimations in Forestry -- 21. Hyperspectral Identification of Selected Dipterocarp Montane at the Species Level -- 22. Tree Biophysical Parameters Retrieval from Multi-source Remote Sensing Data Fusion.
    Abstract: This edited book is a collection of information on recent advancements in remote sensing for forestry application. The main focus of this book is to address the novel applications in remote sensing in terms of recent techniques, sensors, methods and data collection. Remote sensing has been used for many decades. Today, remote sensing is heavily utilized in forest management, which is acquired from airborne and space-borne platforms using satellite data. In recent years, there have been rapid advances in the new types of sensors. The new generations of satellite sensors are introduced not only to provide important information on forest ecosystems, but also to improve the techniques and accuracies obtained by the traditional approaches. Researchers have become increasingly aware of the potential of remote sensing to address important forestry issues and challenges. The number of forestry publications using remote sensing has grown very rapidly, and this is noticeable with many recent technologies and applications. This book provides valuable source of reference to foresters, researchers, ecologists, climate change scientists and scholars who use remote sensing in their work. Furthermore, it serves as an academic book for undergraduate and graduate students of forestry, agriculture, natural resources and environmental sciences. The book demonstrates and engages the students how the new advancements in remote sensing technology and theory relate to the many real-world forestry applications. It gives readers deeper understanding on how remote sensing has come a long way and evolved into a mature science in the past five decades.
    Type of Medium: Online Resource
    Pages: XVII, 458 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811942006
    DDC: 634.9
    Language: English
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotic communities. ; Ecology . ; Environmental chemistry. ; Environmental sciences Social aspects. ; Ecosystems. ; Ecology. ; Environmental Chemistry. ; Environmental Social Sciences.
    Description / Table of Contents: 1 Introduction to Airborne Particulate Matter - Source, Chemistry and Health -- 2 Emission Sources of Particulate Matter -- 3 Geographic Distribution and Transport of Atmospheric Particulate Matter -- 4 Airborne particles in indoor and outdoor environments -- 5 High-resolution ambient record of aerosols over Delhi and associated typical health effects -- 6 Characterization of Primary and Secondary Airborne Particulate -- 7 Toxicological implications of fine particulates: sources, chemical composition and possible underlying mechanism -- 8 Bioaerosol and its impact on human health -- 9 Human Health Effects of Particulate Matter -- 10 Impacts and Responses of Particulate Matter Pollution on Vegetation -- 11 Mitigation and Management of Ambient Particulate Matter -- 12 Particulate Matter Regulatory Policies: National and Global Approach. .
    Abstract: This book is about airborne particulate matter, sources, chemistry and health and contained a complete information about their emission source, transport, atmospheric chemistry, distribution at local, regional and global levels, and their level in indoor and outdoor settings. Primary and secondary particulate matters in the ambient atmosphere also describe in detail. Analytical techniques, statistical tools and mathematical models used in airborne particulate research is also described. This book also covers the important aspects of the particulate matter chemistry in atmosphere, and their adverse impact on plant and human health. A detailed insight about the harmful impact of airborne particulate matter (biogenic and anthropogenic both) on different human system is described in detail. The toxicological significance of particulate matter on human body was also mentioned. The mitigation, management and regulatory policies to control ambient particulate matter is also provided. This book is also written in simple language with helpful photographs, diagrams, tables and flowcharts which will make the reader comfortable in understanding the concepts a more relatively easier way. Overall, the present book is a valuable tool for students working in the fields of Atmospheric Science, Environmental Science, Biological Sciences, Epidemiology and Agriculture Science. This book also a unique resource for environmental consultants, researchers, policymakers and other professionals involved in air quality, plant and human health.
    Type of Medium: Online Resource
    Pages: XIX, 314 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811653872
    DDC: 577
    Language: English
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  • 88
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical microbiology. ; Parasitology. ; Biomedical Research. ; Medical Microbiology. ; Parasitology.
    Description / Table of Contents: Preface -- Chapter1. Advances in experimental research about periodontitis: lessons from the past, ideas for the future (Julien Santi-Rocca) -- Part I: Periodontal microbiota -- Chapter 2. Microbiota in Periodontitis: advances in the omic era (Shao Bing Fong, Emile Boyer, Martine Bonnaure-Mallet, Vincent Meuric) -- Chapter 3. Aggregatibacter actinomycetemcomitans: from basic to advanced research (Abdelhadi Hbibi, Amal Bouziane, Badiaa Lyoussi, Mimoun Zouhdi, Driss Benazza) -- Chapter 4. Meta-analyses on the Periodontal Archaeome (Jéssica Alves de Cena, Yuri Silvestre-Barbosa, Aline Belmok, Cristine Miron Stefani, Cynthia Maria Kyaw, Nailê Damé-Teixeira) -- Chapter 5. Parasites in periodontal health and disease: a systematic review and meta-analysis (David Felipe Martin-Garcia, Malik Sallam, Gabriela Garcia, Julien Santi-Rocca) -- Chapter 6. Fungi - a component of the oral microbiome involved in periodontal diseases (Justyna Karkowska-Kuleta, Dorota Satala, Magdalena Smolarz, Marcin Zawrotniak, Maria Rapala-Kozik) -- Chapter 7. Herpesviruses in periodontitis: An umbrella review (Aleksandar Jakovljevic, Miroslav Andric, Jelena Jacimovic, Jelena Milasin, Javier Enrique Botero) -- Part II: Periodontitis pathophysiology -- Chapter 8. Recent updates on microbial biofilms in periodontitis: an analysis of in vitro biofilm models (Maick Meneguzzo Prado, Nathalia Figueiredo, Andréa Pimenta, Tamires Szeremeske Miranda, Magda Feres, Luciene Cristina Figueiredo, Josiane de Almeida, Bruno Bueno-Silva) -- Chapter 9. Update on B cell response in periodontitis (Julien Demoersman, Jacques Olivier Pers) -- Chapter 10. Polarization profiles of T lymphocytes and macrophages responses in periodontitis (Franco Cavalla, Marcela Hernández) -- Chapter 11. Complementary experimental methods in genetics open up new avenues of research to elucidate the pathogenesis of periodontitis (Arne S. Schaefer) -- Part III: Periodontitis-associated conditions -- Chapter 12. Update on the bidirectional link between diabetes and periodontitis (Leila Salhi, Michèle Reners) -- Chapter 13. Periodontitis as a risk factor for Alzheimer’s disease: the experimental journey so far, with hope of therapy (Alice Harding, Shalini Kanagasingam, Richard Welbury, Sim K. Singhrao) -- Chapter 14. Cardiovascular diseases and periodontitis (Peter Riis Hansen, Palle Holmstrup) -- Part IV: Therapeutic management of periodontitis -- Chapter 15. Update on the role of cytokines as oral biomarkers in the diagnosis of periodontitis (Triana Blanco-Pintos, Alba Regueira-Iglesias, Carlos Balsa-Castro, Inmaculada Tomás) -- Chapter 16. Non-surgical periodontal treatment: SRP and innovative therapeutic approaches (Alexia Vinel, Antoine Al Halabi, Sébastien Roumi, Hélène Le Neindre, Pierre Millavet, Marion Simon, Constance Cuny, Jean-Sébastien Barthet, Pierre Barthet, Sara Laurencin-Dalicieux) -- Chapter 17. Update on the roles of oral hygiene and plaque control on periodontal disease (Leila Salhi, Bruno De Carvalho, Michèle Reners) -- Chapter 18. Multi-photonic adjunctive therapy for the management of periodontitis: recent advances and new treatment approach (Marco Giannelli, Daniele Bani) -- Chapter 19. Probiotics during the therapeutic management of periodontitis (Flavia Furlaneto, Karin Hitomi Ishikawa, Michel Reis Messora, Marcia P A Mayer) -- Chapter 20. Periodontal cell therapy: a systematic review and meta-analysis (Antoine Dubuc, Valérie Planat-Bénard, Mathieu Marty, Paul Monsarrat, Philippe Kémoun) -- Index.
    Abstract: Periodontitis is a disease that affects more than half the adult population in the world. Treatment is often based on ancient recommendations consisting in mechanically removing material from damaged zones. However, novel therapeutic management strategies exist, from prevention to efficient treatment, and regeneration. The need of integrative approaches to circumvent this worldwide pledge can be achieved through: A better understanding of this complex disease by promoting scientific research and a comprehensive multidisciplinary approach, including epidemiology, microbiology, immunology, physiology, therapeutics, psychology, etc. A better outreach by promoting vulgarization and recommendations for health professionals. A better information of the empowered patients, leading them to consider prevention and to take part in their therapeutic course. The book “Periodontitis: Advances in Experimental Research” includes a timely collection of chapters covering all the fields of research about periodontitis, consisting in concise reviews by the best specialists themselves and with clinical perspectives for periodontitis. Recent technological advances have allowed to explore shadowed areas of periodontology. The book “Periodontitis: Advances in Experimental Research” is a unique occasion to set a milestone for a more integrated field of periodontitis, with a broad scientific, medical, and public audience thanks to dedicated sections in each chapter: Abstract and main body (scientific audience and expert clinicians) Highlights (scientific audience and clinicians) Impact for Practice (clinicians and economical/political decision makers) Summary for Patients (patients and economical/political decision makers).
    Type of Medium: Online Resource
    Pages: XIII, 402 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030968816
    Series Statement: Advances in Experimental Medicine and Biology, 1373
    DDC: 610.72
    Language: English
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  • 89
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Ecological genetics. ; Evolutionary genetics. ; Parasitology. ; Microbial genetics. ; Microbial ecology. ; Zoology. ; Ecological Genetics. ; Evolutionary Genetics. ; Parasitology. ; Microbial Genetics. ; Environmental Microbiology. ; Zoology.
    Description / Table of Contents: Chapter 1: Concept of molecular systematics -- Chapter 2: Parasitic helminths of medical and veterinary importance -- Chapter 3: Overview of parasitic helminth diversity: how molecular systematics is involved -- Chapter 4: Molecular evolution of parasitic helminths -- Chapter 5: Challenges of species delimitation for parasitic helminths -- Chapter 6: Molecular genetic markers: general use in parasitic helminth researches -- Chapter 7: PCR and DNA sequencing: guidelines for PCR, primer design, and sequencing for molecular systematics and identification -- Chapter 8: DNA sequence alignment and phylogenetic inferences: guidelines for analysis and the selection of appropriate methods for molecular systematics -- Chapter 9: Parasitic helminth sample preparation for taxonomic study -- Chapter 10: Molecular systematics of nematodes -- Chapter 11: Molecular systematics of trematodes -- Chapter 12: Molecular systematics of cestodes -- Chapter 13: DNA taxonomy of parasitic helminths -- Chapter 14: Implementation of genetic markers from molecular systematics to DNA taxonomy and field applications -- Chapter 15: Concluding remarks and further prospective.
    Abstract: This book aims to provide fundamental knowledge and information for research in molecular systematics on parasitic helminths (nematode, trematode, cestode). The shreds of evidence of molecular systematics studies will be compiled and discussed in terms of the utilities and pitfalls of the genetic marker used for various purposes, which have been implemented for molecular systematics of parasitic nematodes, cestodes, and trematodes. Moreover, this book will also provide the procedure for research on molecular systematics and DNA taxonomy as the guideline to explore parasitic helminths. Finally, the further perspectives of utilizing genetic markers for molecular studies on parasitic helminths will be addressed in the context of applications from the laboratory to fieldwork such as DNA barcoding and environmental DNA metabarcoding of parasitic helminths. The book will benefit postgraduate students and researchers requiring the detailed knowledge of molecular systematics, as well as researchers desiring a guideline to select genetic markers and analyze DNA sequences to make phylogenetic inferences.
    Type of Medium: Online Resource
    Pages: XIX, 396 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811917868
    DDC: 576.58
    Language: English
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  • 90
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Veterinary medicine. ; Otorhinolaryngology. ; Physiology. ; Dermatology. ; Veterinary Clinical Medicine. ; Otorhinolaryngology. ; Animal Physiology. ; Dermatology.
    Description / Table of Contents: Chapter 1. Technical Information of the Video-Oto-Endoscope -- Chapter 2. Patient Preparation and Otoendoscopy Operative Procedure -- Chapter 3. Ear Anatomy -- Chapter 4. Video Otoscopy Procedures -- Chapter 5. Indications of VOE in Canine and Feline Ear Diseases.
    Abstract: This atlas provides a step-by-step manual in using the video-oto-endoscope (VOE) as a tool to study ear diseases in cats and dogs. Illustrated by numerous high-resolution images and case studies, the book explains in a highly accessible manner when and how to use VOE. It teaches how to differ between a normal and a pathological animal ear and guides the reader in diagnosing a particular disease. The book's main section provides in-depth information on causes, clinical picture, and imaging of ear diseases such as acute otitis externa, chronic otitis externa, and otitis media in small animals. Moreover, the atlas introduces technical fundamentals of the instrument and gives tips for its correct handling and cleaning. Further, readers are instructed on how to best prepare the animal patient for examination by VOE. The atlas addresses veterinary practitioners and veterinary technicians who are interested in performing otological examinations in cats and dogs. .
    Type of Medium: Online Resource
    Pages: XIII, 185 p. 252 illus., 236 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030989118
    DDC: 636.0896
    Language: English
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  • 91
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Autoimmunity. ; Inflammation. ; Immunogenetics. ; Tumors Immunological aspects. ; Immunology. ; Translational Immunology. ; Autoimmunity. ; Inflammation. ; Immunogenetics. ; Tumour Immunology.
    Description / Table of Contents: 1 Cells and tissues of the immune system -- 2 Innate immunity and inflammation -- 3 Adaptive immunity and antigen receptor diversity -- 4 B cell immunity: BCRs, antibodies and their effector functions -- 5 Antigen-presenting cells and the major histocompatibility complex -- 6 T cell immunity: TCRs and their effector functions -- 7 Immunity to bacterial pathogens and the microbiome -- 8 Immunity to viral pathogens and the virome -- 9 Tolerance and transplantation immunology -- 10 Immunological hypersensitivities: Allergy and autoimmunity -- 11 Cancer immunology.
    Abstract: This textbook aims to describe in a condensed form the essentials of molecular immunology behind bacterial infections, the microbiome, viral infections (such as influenza and COVID-19), organ transplantations, autoimmunity, allergy and tumor immunology. The book emphasizes the impact of immunology in maintaining our health and preventing disease. Our immune system protects us not only from severe consequences of infectious diseases and getting cancer, but is also able to harm us severely via sepsis, cytokine storms and anaphylactic shocks. Molecular understanding of immunology should allow the reader a more rational handling of common diseases, most of which are associated with chronic inflammation.
    Type of Medium: Online Resource
    Pages: XV, 219 p. 94 illus., 93 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031040252
    DDC: 571.96
    Language: English
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  • 92
    Keywords: Medicine Research. ; Biology Research. ; Cancer. ; Technology Sociological aspects. ; Genomics. ; Biomedical Research. ; Cancer Biology. ; Emerging Technologies. ; Genomics.
    Description / Table of Contents: Chapter 1. Introduction to emerging technologies in biomedical sciences -- Chapter 2. Bioprospecting : boon or curse -- Chapter 3. Growing need for interdisciplinary biomedical research -- Chapter 4. Interplay between theory and experiment : a future approach for biomedical research -- Chapter 5.past, present and future perspectives of biomedical innovation in india -- Chapter 6. Systems biology approaches to study disease comorbidities -- Chapter 7. Bioinformatics the interactome of multidisciplinary approaches -- Chapter 8. Role of artificial intelligence in diagnosis of infectious diseases -- Chapter 9. Dna digital data storage breakthroughs in biomedical research. Chapter 10. Biomedical applications cloud-based iot -- Chapter 11. Next generation sequencing in cancer research -- Chapter 12. Crispr: genome editing and beyond -- Chapter 13. Omics in tuberculosis diagnosis : today and tomorrow -- Chapter 14. Advances in proteomic approaches for chronic kidney disease -- Chapter 15. 3 d bioprinting of tissues and organs : a new paradigm in regenerative medicine and biomedical engineering -- Chapter 16. Virtual planning, rapid prototyping and 3-d printing in orthopedic surgery -- Chapter 17. Tissue chips: contemporary applications and advancementstissue chips: contemporary applications and advancements -- Chapter 18. Flow cytometry for measuring neutrophil function -- Chapter 19. Flow cytometer for understanding genome size variation among medicinal herbs and non-edible oil trees of northeast india -- Chapter 20. Raman spectroscopy applications for bacterial detection -- Chapter 21. Microfluidic point-of-care diagnostic devices: a contemporary relevance. Chapter 22. Fluorescent dots for breast cancer management -- Chapter 23. Molecular mimicry : unravelling the role of autoantibodies in autoimmune diseases and infertility -- Chapter 24. Strategies of vaccine development -- Chapter 25. Preclinical models of intimal hyperplasia and restenosis to predict clinical events and develop novel therapies -- Chapter 26. Sphingolipids : a roadmap from biomarker identification to clinical application -- Chapter 27. Future of gastrointestinal endoscopy -- Chapter 28. Beating heart in a box : the future of cardiac transplant -- Chapter 29. The journey of coronary stent technology -- Chapter 30. Materiovigilance in clinical surgery.
    Abstract: This book, which is the first volume of Biomedical Translational Research, summarizes emerging technologies in healthcare. The book reviews the advancements in biomedical sciences in genomics, immunology, stem cell, tissue engineering, nanotechnology, computational and structural biology, biomedical engineering, and telemedicine biology. The book highlights the applications of artificial intelligence in the diagnosis of infectious diseases and examines the role of system biology approaches for understanding human complexity, variability, and its influence on health and diseases. It presents the applications of flow cytometry in monitoring the progression and treatment of disease. It covers emerging technologies in cancer research, including CRISPR-Cas9, NGS, and nanotechnology. This book is a useful source of information for clinical researchers, basic scientists, biomedical engineers, and computational biologists.
    Type of Medium: Online Resource
    Pages: XIII, 505 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643453
    DDC: 610.72
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Virology. ; Microbial ecology. ; Virology. ; Microbial Ecology.
    Description / Table of Contents: Chapter 1. Bacteriophages, a Brief Introduction -- Chapter 2. A Closer Overview of Phage Infections -- Chapter 3.Evolutionary Biology Basics -- Chapter 4. Brief Introduction to Phage Ecology -- Chapter 5.Bacterial Mutation Associated with Phages: Insertions -- Chapter 6. Bacterial Mutation Associated with Phages: Deletions -- Chapter 7. Genetic Drift and Phages -- Chapter 8. Phages and Asexual Bacterial Populations -- Chapter 9.Phage Impact on Non-Random Mating Among Bacteria -- Chapter 10. Genetic Migration and Phages -- Chapter 11. Bacterial Reproductive Isolation and Its Violation by Phages -- Chapter 12. Phage-Provided Environmental DNA and Superspreading -- Chapter 13. Transduction of Large Amounts of DNA -- Chapter 14. Phage Morons -- Chapter 15. Why Lysogenic Conversion? -- Chapter 16. Prophages Preventing Phage Superinfection -- Chapter 17. Domestication of Phage Genes -- Chapter 18.Resistance to Phages, Part I: Overview -- Chapter 19. Resistance to Phages, Part II: Bacteria Live! -- Chapter 20.Resistance to Phages, Part III: Bacteria Die..-Chapter 21. Bacterial Mutation to Phage Resistance -- Chapter 22. Pleiotropic Costs of Phage Resistance -- Chapter 23. Concepts of Natural Selection in Light of Phage Exposure -- Chapter 24. Frequency-Dependent Selection in Light of Phage Exposure -- Chapter 25. A Primer on Phage-Bacterium Antagonistic Coevolution.
    Abstract: This monograph emphasizes the many facets of bacterial evolution as impacted by bacterial interactions with phages, as well as, to a lesser degree, the evolutionary impact of phages on other organisms, including other phages. The book starts with a general overview of bacteriophages. Topics discussed in detail include but are not limited to mutagenesis, migration, natural selection and genetic drift as the drivers of evolution as well as an extensive discussion from the author’s unique perspective on phage ecology. .
    Type of Medium: Online Resource
    Pages: XXV, 377 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030943097
    DDC: 579.2
    Language: English
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  • 94
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical sciences. ; Medicine Research. ; Biology Research. ; Science Social aspects. ; Communication in science. ; Penmanship. ; Health Sciences. ; Biomedical Research. ; Science and Technology Studies. ; Science Communication. ; Writing Skills.
    Description / Table of Contents: Part I. Introduction: The Pathway to Publishing -- Part II. Most common errors -- 1. General research and writing practices -- 2. Content of quantitative papers -- 3. Mechanics of writing -- 4. Grammatical structures and stylistic strategies -- 5. Achieving clarity and conciseness -- 6. Recording scientific data -- 7. Approaching publication -- 8. Slide and poster presentations.
    Abstract: Writing manuscripts is central to the advance of scientific knowledge. For an early career aspiring scientist, writing first author manuscripts is an opportunity to develop critical skills and to credential their expertise. Writing manuscripts, however, is difficult, doubly so for scientists who use English as a second language. Many science students intentionally avoid a writing-intensive curriculum. Careful, thorough reviews of draft manuscripts are difficult to secure, and experienced scientific supervisors face more demands on their time than they have time available. Weak draft manuscripts discourage supervising scientists investing the time to coach revisions. It is easier for experienced scientists to ignore the request, or to simply rewrite the article. Early career scientists are motivated to address these barriers but specific advice is difficult to find, and much of this advice is behind a pay wall. This essential, open access text presents writing lessons organized as common errors, providing students and early-career researchers with an efficient way to learn, and mentors with a quick-reference guide to reviewing. Error descriptions include specific examples drawn from real-world experiences of other early-career writers, and suggestions for how to successfully address and avoid these in the future. Versions of this book have been used by Stanford University, UC Davis, Johns Hopkins, and numerous international institutions and organizations for over a decade. This book is licensed under the terms of the Creative Commons Attribution 4.0 International License "http://creativecommons.org/licenses/by/4.0/", which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made The images or other third party material in this book are included in the book's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the book's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
    Type of Medium: Online Resource
    Pages: XIII, 186 p. 55 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030981754
    DDC: 610
    Language: English
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    Keywords: Pharmaceutical chemistry. ; Pharmacology. ; Drug delivery systems. ; Biotechnology. ; Pharmaceutics. ; Pharmacology. ; Drug Delivery. ; Biotechnology.
    Description / Table of Contents: History and Present Scenario of Computers in Pharmaceutical Research and Development.-Historical Developments on Computer Applications in Pharmaceutics -- Computer Aided Formulation Development -- Quality-by-Design in Pharmaceutical Development -- Teaching Principles of DoE as an Element of QbD for Pharmacy Students -- Computer-Assisted Manufacturing of Medicines -- Computer Aided Biopharmaceutical Characterization: Gastrointestinal Absorption Simulation and In Silico Computational Modeling -- Computer Simulation and Modeling in Pharmacokinetics and Pharmacodynamics -- Physiologicallly Based Pharmacokinetic Modelling -- Computers in Clinical Development -- Artificial Intelligence (AI) -- Robotic Automation of Pharmaceutical and Life Science Industries -- Soft Robots for the Delivery of Drugs -- Use of Computers and Internet in Scholarly Information Retrieval -- Patent Searching -- Computer Aided Drug Design (CADD) -- Quantitative Structure Property Relationship (QSPR) Modeling Applications in Formulation Development -- Modeling Approaches for Studies of Drug-Polymer Interactions in Drug Delivery Systems -- Computers in Pharmaceutical Analysis -- Telemedicine -- Bioinformatics in Drug-Design and Delivery -- Statistical Modeling Techniques -- Molecular Modelling of Nanoparticles -- Pharmaceutics Informatics: Bio/chemoinformatics in Drug Delivery -- Computer-aided Development and Testing of Human Extra-thoracic Airway Models for Inhalation Drug Delivery.
    Abstract: This book examines the role of computer-assisted techniques for discovering, designing, optimizing and manufacturing new, effective, and safe pharmaceutical formulations and drug delivery systems. The book discusses computational approaches, statistical modeling and molecular modeling for the development and safe delivery of drugs in humans. The application of concepts of QbD (Quality by Design), DoE (Design of Experiments), artificial intelligence and in silico pharmacokinetic assessment/simulation have been made a lot easier with the help of commercial software and expert systems. This title provides in-depth knowledge of such useful software with illustrations from the latest researches. The book also fills in the gap between pharmaceutics and molecular modeling at micro, meso and maro scale by covering topics such as advancements in computer-aided Drug Design (CADD), drug-polymer interactions in drug delivery systems, molecular modeling of nanoparticles and pharmaceutics/bioinformatics. This book provides abundant applications of computers in formulation designing and characterization are provided as examples, case studies and illustrations. Short reviews of software, databases and expert systems have also been added to culminate the interest of readers for novel applications in formulation development and drug delivery. Computer-aided pharmaceutics and drug delivery is an authoritative reference source for all the latest scholarly update on emerging developments in computed assisted techniques for drug designing and development. The book is ideally designed for pharmacists, medical practitioners, students and researchers. .
    Type of Medium: Online Resource
    Pages: XVII, 762 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811651809
    DDC: 615.19
    Language: English
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    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Medical microbiology. ; Microbial genetics. ; Industrial microbiology. ; Microbiology. ; Biomedical Research. ; Medical Microbiology. ; Microbial Genetics. ; Industrial Microbiology. ; Microbiology.
    Description / Table of Contents: Chapter 1. Epidemiology of Oral Squamous Cell Carcinoma in Indian Scenario -- Chapter 2. Risk factors for Oral Squamous Cell Carcinoma in the Indian population -- Chapter 3. Molecular Carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 4. Inflammation and Infection in Cancer -- Chapter 5. Role of Inflammation and Infection in Oral Squamous Cell Carcinoma -- Chapter 6. Normal Microbiome of Oral cavity -- Chapter 7. Oral Microbiome in Oral Squamous Cell Carcinoma -- Chapter 8. Microbial Dysbiosis in Oral Squamous Cell Carcinoma -- Chapter 9. Bacteria induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 10. Virus induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 11. Fungi: Culprits or Bystanders in Oral Squamous Cell Carcinoma -- Chapter 12. Microbial ‘omics’ in Oral Squamous Cell Carcinoma -- Chapter 13. Implications and Future perspectives.
    Abstract: This book helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention. The book takes the readers through interesting topics such as the epidemiology and etiology of OSCC, the hallmarks of cancer, and the role of inflammation in OCSS. It presents the difference between the normal and diseased oral microbiome. It further describes the carcino-pathogenesis of various groups. Finally, it discusses the clinical correlation of the observations and what the future looks like for this area of research. The book is interesting for medical students, researchers and clinicians, alike. The knowledge from the book can be exploited practically and used for designing further experiments.
    Type of Medium: Online Resource
    Pages: XIII, 172 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811905926
    DDC: 610.72
    Language: English
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  • 97
    Keywords: Food science. ; Food Analysis. ; Food Safety measures. ; Food Microbiology. ; Food security. ; Food Science. ; Food Analysis. ; Food Safety. ; Food Microbiology. ; Food Security.
    Description / Table of Contents: Chapter 1. General Discussion -- Chapter 2. Product Description -- Chapter 3. Processing of Shrimp -- Chapter 4. Food Additives and Soaking -- Chapter 5. Defects of Shrimp -- Chapter 6. Traceability in Shrimp -- Chapter 7. Plant Sanitation and Hygiene -- Chapter 8. Packaging, Labeling and Storage -- Chapter 9. Inspection of Frozen Shrimp -- Chapter 10. Laboratory Analysis -- Chapter 11. Shipment and Shipping Documents -- Chapter 12. Audit, Certification and Payment -- Chapter 13. Frozen Shrimp and Other Seafood Based Value-Added Products -- Chapter 14. Recommendation and Conclusion.-.
    Abstract: The book is a practical guide for the various steps in the post-harvest technology of frozen shrimps. Shrimps are one of the most common and popular types of seafood consumed globally. The book discusses some of the most sought-after shrimps such as Penaeus monodon, P. vannamei, and Macrobrachium rosenbergii. Good-quality shrimp is a prerequisite for the seafood business as it is used for human consumption. Lack of proper knowledge in raw materials handling and post-harvest processing is the main obstacle in quality shrimp production. Complex business policy, commitment break in both parties (buyers and sellers), competition with other seafood-producing countries, and fluctuation of currency in international seafood market are the factors affecting international seafood business. This book closes this gap in literature and facilitates the production of excellent-quality exportable frozen shrimp through informed practices from experts. The book includes information about packaging of frozen shrimp, inspection, and shipment. It also compiles different mathematical calculations which are in practiced in the processing industries. The book is essential reading for professionals in the shrimp producing and processing industries. It is also useful for researchers in fisheries science, aquaculture, food technology, and food microbiology.
    Type of Medium: Online Resource
    Pages: XXV, 267 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811915666
    DDC: 641.3
    Language: English
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  • 98
    Keywords: Stress (Physiology). ; Plants. ; Plant physiology. ; Plant biotechnology. ; Plant genetics. ; Plant Stress Responses. ; Plant Physiology. ; Plant Biotechnology. ; Plant Genetics.
    Description / Table of Contents: Chapter 1. Morphological, architectural and biochemical modifications of cereal crops during abiotic stress -- Chapter 2. Cereal physiology, flowering and grain yield under salinity and drought stress -- Chapter 3. Physiology, flowering and grain yield under abiotic stress imposed by heavy metals -- Chapter 4. Priming effect in developing abiotic stress tolerance in cereals through metabolome reprograming -- Chapter 5. Understanding abiotic stress tolerance in cereals through genomics and proteomics approaches -- Chapter 6. Metabolome analyses in response to diverse abiotic stress -- Chapter 7. Metabolomic profiling of different cereals during biotic and abiotic stresses -- Chapter 8. Plant breeding strategies for abiotic stress tolerance in cereals -- Chapter 9. Transgenic strategies to develop abiotic stress tolerance in cereals -- Chapter 10. Genetically engineered cereals tolerant to abiotic stress -- Chapter 11. Genome editing and CRISPR-Cas technology for enhancing abiotic stress tolerance in cereals -- Chapter 12. Abiotic stress tolerance in cereals through genome editing -- Chapter 13. Varietal physiology, metabolic regulation and molecular responses of rice genotypes to diverse environmental stresses -- Chapter 14. Breeding and Omics Approaches to Understand Abiotic Stress Response in Rice -- Chapter 15. Genomics and transcriptomics approaches to understand abiotic stress response in rice -- Chapter 16. Biochemical and molecular mechanism of wheat to diverse environmental stresses -- Chapter 17. How microRNAs Regulate Abiotic Stress Tolerance in Wheat? A Snapshot -- Chapter 18. Molecular-genetic studies, breeding and genomics-based approaches to develop abiotic stress tolerance in sorghum -- Chapter 19. MicroRNAs shape the Tolerance Mechanisms against Abiotic Stress in Maize -- Chapter 20. Transcriptome, proteome and metabolome profiling for abiotic stress tolerance in maize and barley -- Chapter 21. Omics tools to understand abiotic stress response and adaptation in rye, oat and barley -- Chapter 22. Genomic tools and proteomic determinants for abiotic stress tolerance in pearl millet (Pennisetum glaucum) and foxtail millet (Setaria italica L.) -- Chapter 23. Advancement in Omics Technologies for Enhancing Abiotic Stress Tolerance in Finger millet -- Chapter 24. Buckwheat (Fagopyrum esculentum) response and tolerance to abiotic stress -- Chapter 25. Abiotic Stress Response and Adoption of Triticale.
    Abstract: The edited book highlights various emerging Omics tools and techniques that are currently being used in the analysis of responses to different abiotic stress in agronomically important cereals and their applications in enhancing tolerance mechanism. Plants are severely challenged by diverse abiotic stress factors such as low water availability (drought), excess water (flooding/ waterlogging), extremes of temperatures (cold, chilling, frost, and heat), salinity, mineral deficiency, and heavy metal toxicity. Agronomically important cereal crops like Rice, Wheat, Maize, Sorghum, Pearl Millet, Barley, Oats, Rye, Foxtail Millets etc. that are the major sources of food material and nutritional components for human health are mostly exposed to abiotic stresses during the critical phases of flowering and grain yield. Different Omics platforms like genomics, transcriptomics proteomics, metabolomics and phenomics, in conjunction with breeding and transgenic technology, and high throughput technologies like next generation sequencing, epigenomics, genome editing and CRISPR-Cas technology have emerged altogether in understanding abiotic stress response and strengthening defense and tolerance mechanism of different cereals. This book is beneficial to different universities and research institutes working with different cereal crops in the areas of stress physiology, stress-associated genes and proteins, genomics, proteomics, genetic engineering, and other fields of molecular plant physiology. The book can also be used as advanced textbook for the course work of research and master’s level students. It will be of use to people involved in ecological studies and sustainable agriculture. The proposed book bring together the global leaders working on environmental stress in different cereal crops and motivate scientists to explore new horizons in the relevant areas of research.
    Type of Medium: Online Resource
    Pages: IX, 615 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811901409
    DDC: 581.788
    Language: English
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  • 99
    Keywords: Toxicology. ; Reproductive health. ; Reproduction. ; Physiology. ; Cytology. ; Developmental biology. ; Environmental chemistry. ; Toxicology. ; Reproductive Medicine. ; Reproductive Physiology. ; Cell Biology. ; Developmental Biology and Stem Cells. ; Environmental Chemistry.
    Description / Table of Contents: Oxidative stress and toxicity in reproductive biology and medicine: Historical perspectives and future horizons in male fertility -- Reactive Oxygen Species in the Reproductive System: Sources and Physiological Roles -- Pathological Roles of Reactive Oxygen Species in Male Reproduction -- Molecular Interactions Associated with Oxidative Stress Mediated Male Infertility: Sperm and Seminal Plasma Proteomics -- Unraveling the Molecular Impact of Sperm DNA Damage on Human Reproduction -- Role of Infection and Leukocytes in Male Infertility -- Bacteriospermia and Male Infertility: Role of Oxidative Stress -- Oxidant-Sensitive Inflammatory Pathways and Male Reproductive Functions -- Oxidative Stress and Idiopathic Male Infertility -- Oxidative Stress and Varicocele-Associated Male Infertility -- Oxidative Stress in Men with Obesity, Metabolic Syndrome and Type 2 Diabetes Mellitus: Mechanisms and Management of Reproductive Dysfunction -- Metabolic dysregulation and sperm motility in male infertility -- Tale of viruses in male infertility -- Pathogenesis of Viral Infections and Male Reproductive Health: An Evidence-Based Study -- Sperm redox system equilibrium: Implications for fertilization and male fertility.
    Abstract: This book discusses the role of oxidative stress in human reproduction with a focus on men’s health. The physiological roles of reactive oxygen species (ROS) in male fertility are the focus in this book. This topic is important because oxidative stress is a result of the imbalance between ROS and antioxidants in the body which may lead to sperm damage (DNA or count), deformity, and eventually, male infertility. Therefore, for a better understanding of the molecular mechanisms related to male genotoxicity and its regulation in infertility, this book provides an up-to-date view on the impact of oxidative stress factors in male reproduction . The main aim of this book is to collect a series of research articles and reviews from a diverse group of scientists to share their research work on the role of ROS or oxidative stress in physiological and pathological states in relation to (in)fertility in the male. This book presents various state-of-the-art chapters of the recent progress in the field of cellular toxicology and clinical manifestations of various issues related to men’s health and fertility. Topics include cell signaling, DNA damage and infertility, the pathophysiology of disease instigation and distribution, immune toxicity and prevention.
    Type of Medium: Online Resource
    Pages: XII, 379 p. 28 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030893408
    Series Statement: Advances in Experimental Medicine and Biology, 1358
    DDC: 615.90072
    Language: English
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  • 100
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cytology. ; Neurosciences. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Cell Biology. ; Neuroscience. ; Biomedical Research. ; Pharmacology.
    Description / Table of Contents: A historical and evolutionary view of tight junctions -- Tricellular tight junctions -- Mechanosensitivity of tight junctions -- Intracellular traffic and non-canonical roles of ZO-2 protein -- Impact of claudin-2 and occludin expression in inflammation disorders -- Tight junctions in the inflamed gut -- Intestinal barrier disruption by enteropathogenic Escherichia coli -- Tight junction barrier function regulation by microbiota -- Claudin-7 participation in cell-substrate adhesion, cell migration, salt balance in the renal collecting duct and gut cell renewal and differentiation -- Regulation of the alveolar epithelial barrier by claudin-5 -- Regulation of the blood-retinal barrier by occludin phosphorylation, norrin and sonic hedgehog signaling -- Transmigration of metastatic cells through the blood-brain barrier -- Endocytosis of tight junction proteins -- Regulated degradation of claudins. .
    Abstract: This volume explores the dynamic topic of tight junctions. The book focuses on tight junctions' role in sealing adjacent epithelial cells in a narrow band just beneath their apical surface. The book explains how tight junctions consist of a network of claudins and other proteins, and delves into how they hold cells together and form functional and protective barriers, regulating the passage of molecules and ions through the space between cells. The book opens with a discussion of the evolution of research on tight junctions, discussing a range of primary areas of growth, including the current knowledge on the particular physiological function of different claudins due to the development of an array of knock out mice. The chapters also explore in-depth studies of tight junctions in specific tissues (gut, lung and endothelia). This book offers a comprehensive understanding on post-translational modifications of occludin and its impact on tight junction function, as well as the molecular composition and function of tricellular tight junctions. This volume is particularly relevant to students and scientists in neuroscience, cell biology, physiology, cell differentiation, and cancer research.
    Type of Medium: Online Resource
    Pages: XII, 334 p. 47 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030972042
    DDC: 571.6
    Language: English
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