ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

1

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Seismic Waves and Sources (1981)

A. Ben-Menahem ; S. J. Singh

Springer

In: New York, 1108 pp., Springer, vol. 96, pp. 225, (ISBN 0-471-95596-5)

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Publikationsdatum: 1981

Schlagwort(e): FROTH ; RUB ; GMG ; 3.15.80 ; Textbook of geophysics ; Seismology ; Waves ; Wavelet processing ; SModelling ; Dislocation ; Elasticity theory of dislocations ; Source

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BIBLIOGRAFIE SEISMOLOGIE

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2

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Condensed Matter; Magnetic Properties. Magnetic and Other Properties of Oxides and Related Compounds Part b: Spinels, Fe Oxides and Fe-Me-O Compounds (1980)

K.-H. Hellwege ; Hellwege, A. M., Eds.

Springer

In: Berlin, Springer, vol. III/12, Supplement to III/4, no. XVI:, pp. 1-14, (ISBN 0-87590-299-5 (soft cover))

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Publikationsdatum: 1980

Schlagwort(e): Handbook of geophysics ; Handbook of physics ; Handbook of mineralogy

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3

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Piezoelektrische Meßtechnik (1980)

J. Tichy ; G. Gautchy

Springer

In: Dordrecht, IX+266 pp., Springer, vol. 3, no. ALEX(01)-FR-77-01, AFTAC Contract F08606-76-C-0025, pp. 329, (ISBN 1-903544-06-8)

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Publikationsdatum: 1980

Schlagwort(e): SEModelling ; Instruments ; Laboratory measurements

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4

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Transformation of catecholaminergic precursors into glucagon (A) cells in mouse embryonic pancreas. (1981)

Teitelman, G. ; Joh, T. H. ; Reis, D. J.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences of the United States of America. 1981; 78(8): 5225-5229. Published 1981 Aug 01. doi: 10.1073/pnas.78.8.5225.

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Publikationsdatum: 1981-08-01

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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5

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Calcitonin: regional distribution of the hormone and its binding sites in the human brain and pituitary. (1981)

Fischer, J. A. ; Tobler, P. H. ; Kaufmann, M. ; [weitere]

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences of the United States of America. 1981; 78(12): 7801-7805. Published 1981 Dec 01. doi: 10.1073/pnas.78.12.7801.

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Publikationsdatum: 1981-12-01

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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6

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Thyroid or glucocorticoid hormone induces pre-growth-hormone mRNA and its probable nuclear precursor in rat pituitary cells. (1981)

Dobner, P. R. ; Kawasaki, E. S. ; Yu, L. Y. ; [weitere]

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences of the United States of America. 1981; 78(4): 2230-2234. Published 1981 Apr 01. doi: 10.1073/pnas.78.4.2230.

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Publikationsdatum: 1981-04-01

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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7

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Immunocytochemical localization of the sex steroid-binding protein of plasma in tissues of the adult monkey Macaca nemestrina. (1980)

Bordin, S. ; Petra, P. H.

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences of the United States of America. 1980; 77(10): 5678-5682. Published 1980 Oct 01. doi: 10.1073/pnas.77.10.5678.

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Publikationsdatum: 1980-10-01

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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8

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MultipleLegionella pneumophilaeffector virulence phenotypes revealed through high-throughput analysis of targeted mutant libraries (2017)

Shames, Stephanie R. ; Liu, Luying ; Havey, James C. ; [weitere]

National Academy of Sciences

In: PNAS - Proceedings of the National Academy of Sciences of the United States of America. 2017; 114(48): E10446-E10454. Published 2017 Nov 13. doi: 10.1073/pnas.1708553114.

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Publikationsdatum: 2017-11-13

Beschreibung: Legionella pneumophilais the causative agent of a severe pneumonia called Legionnaires’ disease. A single strain ofL. pneumophilaencodes a repertoire of over 300 different effector proteins that are delivered into host cells by the Dot/Icm type IV secretion system during infection. The large number ofL. pneumophilaeffectors has been a limiting factor in assessing the importance of individual effectors for virulence. Here, a transposon insertion sequencing technology called INSeq was used to analyze replication of a pool of effector mutants in parallel both in a mouse model of infection and in cultured host cells. Loss-of-function mutations in genes encoding effector proteins resulted in host-specific or broad virulence phenotypes. Screen results were validated for several effector mutants displaying different virulence phenotypes using genetic complementation studies and infection assays. Specifically, loss-of-function mutations in the gene encoding LegC4 resulted in enhancedL. pneumophilain the lungs of infected mice but not within cultured host cells, which indicates LegC4 augments bacterial clearance by the host immune system. The effector proteins RavY and Lpg2505 were important for efficient replication within both mammalian and protozoan hosts. Further analysis of Lpg2505 revealed that this protein functions as a metaeffector that counteracts host cytotoxicity displayed by the effector protein SidI. Thus, this study identified a large cohort of effectors that contribute toL. pneumophilavirulence positively or negatively and has demonstrated regulation of effector protein activities by cognate metaeffectors as being critical for host pathogenesis.

Print ISSN: 0027-8424

Digitale ISSN: 1091-6490

Thema: Biologie , Medizin , Allgemeine Naturwissenschaft

Publiziert von National Academy of Sciences

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