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  • Artikel  (17)
  • Aged  (17)
  • American Association for the Advancement of Science (AAAS)  (17)
  • American Meteorological Society
  • Blackwell Publishing Ltd
  • Nature Publishing Group
  • Springer Nature
  • Springer Science + Business Media
  • 2020-2024
  • 1975-1979  (17)
  • 1960-1964
  • 1978  (17)
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  • Artikel  (17)
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  • American Association for the Advancement of Science (AAAS)  (17)
  • American Meteorological Society
  • Blackwell Publishing Ltd
  • Nature Publishing Group
  • Springer Nature
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Erscheinungszeitraum
  • 2020-2024
  • 1975-1979  (17)
  • 1960-1964
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  • 1
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    Reversible cerebral atrophy in recently abstinent chronic alcoholics measured by computed tomography scans (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-06-02
    Beschreibung: Eight chronic alcoholics received repeated computed tomography scans. Four, who maintained abstinence and functionally improved, showed partially reversible cerebral atrophy. Two nonabstinent patients and two abstinent patients who had completed functional improvement before the first scan showed no change in atrophy.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carlen, P L -- Wortzman, G -- Holgate, R C -- Wilkinson, D A -- Rankin, J C -- New York, N.Y. -- Science. 1978 Jun 2;200(4345):1076-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/653357" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adult ; Aged ; Alcoholism/*pathology/radiography/therapy ; Atrophy ; Brain/*pathology/radiography ; Female ; Humans ; Male ; Middle Aged ; Tomography, X-Ray Computed
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
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    Decrease of human serum fucosyltransferase as an indicator of successful tumor therapy (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-09-29
    Beschreibung: Surgical removal of colon carcinomas leads to a decrease in the rate of incorporation of [14C]fucose into its endogenous acceptor in human serum; normal incorporation rates are attained within 14 days. A similar time course has been determined for alpha2- and alpha3-fucosyltransferase when either desialo- or desialodegalactofetuin are employed as exogenous acceptors. A correlation has also been seen between transferase activity and the therapeutic response of patients with breast cancer. These results indicate that the determination of fucosyltransferase activity can facilitate the diagnosis of neoplasia, and the success of surgery, chemotherapy, or radiation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bauer, C H -- Reutter, W G -- Erhart, K P -- Kottgen, E -- Gerok, W -- New York, N.Y. -- Science. 1978 Sep 29;201(4362):1232-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694511" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Aged ; Breast Neoplasms/*therapy ; Carcinoma/blood/*surgery ; Colonic Neoplasms/blood/*surgery ; Female ; Fucosyltransferases/*blood ; Hexosyltransferases/*blood ; Humans ; Male ; Middle Aged
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
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    Care of the aged: old problems in need of new solutions (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-05-26
    Beschreibung: Long-term care for the aged in the United States is overly dependent upon the nursing home. This hospital-like model for long-term care is particularly inappropriate since it imposes a medical solution on a variety of social problems. An adequate long-term care program requires a range of resources in the community as well as in institutions; sheltered housing options seem a desirable alternative to the nursing home. To ensure the quality of nursing home care, the present focus on setting standards for care activities should be abandoned in favor of a focus on care outcomes (physical, mental, and social). In an effort to change our present perverse incentives in the nursing home industry, the proposal is made that nursing homes be reimbursed according to the degree to which patient outcomes meet predicted outcomes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kane, R L -- Kane, R A -- New York, N.Y. -- Science. 1978 May 26;200(4344):913-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/417403" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Aged ; Financing, Government ; Health Facilities, Proprietary ; *Homes for the Aged/economics ; Humans ; Long-Term Care/*methods ; *Nursing Homes/economics/standards ; Socioeconomic Factors ; United States
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
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    B lymphocyte antigens in sicca syndrome (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-03-31
    Beschreibung: All individuals tested in this study with sicca syndrome, a human autoimmune disease, bear two immunologically distinct and genetically unrelated B lymphocyte antigens that appear similar to the immune response associated (Ia) antigens of the mouse. The genes coding for these two antigens are present in only 37 and 24 percent of normal controls. In animal models Ia antigen genes are closely linked to immune response genes. Our findings suggest that two such genes may be required for the development of sicca syndrome.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Moutsopoulos, H M -- Chused, T M -- Johnson, A H -- Khudsen, B -- Mann, D L -- New York, N.Y. -- Science. 1978 Mar 31;199(4336):1441-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/415366" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adolescent ; Adult ; Aged ; Autoimmune Diseases/*immunology ; B-Lymphocytes/*immunology ; Female ; *Genes, MHC Class II ; Genetic Linkage ; HLA Antigens/analysis/genetics ; Humans ; Isoantigens/*analysis/genetics ; Male ; Middle Aged ; Sjogren's Syndrome/genetics/*immunology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
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    Cohort mortality for prostatic cancer among United States nonwhites (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-06-09
    Beschreibung: In recent decades, age-adjusted mortality rates from prostatic cancer have risen precipitously among blacks, remaining unchanged among whites. It is now the most common cancer among United States black males. When nonwhite mortality rates were examined by age and birth cohort, it was found that peak rates occurred at every age in the cohort of 1896 to 1900, and declined thereafter. This presages an arrest and reversal of the time trend in summary mortality rates as more recent nonwhite cohorts reach the ages of maximum risk.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ernster, V L -- Selvin, S -- Winkelstein, W Jr -- New York, N.Y. -- Science. 1978 Jun 9;200(4346):1165-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/653361" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): *African Continental Ancestry Group ; Age Factors ; Aged ; European Continental Ancestry Group ; Humans ; Male ; Middle Aged ; Prostatic Neoplasms/*mortality
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
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    Cancer death risk in hospitalized mental patients (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-09-15
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fox, B H -- New York, N.Y. -- Science. 1978 Sep 15;201(4360):966-968.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/684429" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Aged ; Female ; Hospitalization ; Humans ; Male ; Mental Disorders/*complications ; Middle Aged ; Neoplasms/*mortality ; Risk ; United States
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
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    Age affect and replicative life-span of fibroblasts of diabetic, prediabetic, and normal donors: another look at the data (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-12-15
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gleason, R E -- Goldstein, S -- New York, N.Y. -- Science. 1978 Dec 15;202(4373):1217-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/725599" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adolescent ; Adult ; Aged ; *Aging ; Cell Division ; Cell Survival ; Cells, Cultured ; Diabetes Mellitus/*physiopathology ; Humans ; Middle Aged ; Prediabetic State/*physiopathology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
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    Chronologic and physiologic age affect replicative life-span of fibroblasts from diabetic, prediabetic, and normal donors (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-02-17
    Beschreibung: Cultured skin fibroblasts from subjects with clinically apparent diabetes mellitus and from subjects genetically predisposed to diabetes have a replicative lifespan that is inversely related to donor age. Fibroblasts from carefully defined normal subjects not predisposed to diabetes fail to show this correlation. The data support the idea that physiologic status of the tissue donor is a more precise determinant of fibroblast replicative lifespan than chronologic age.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goldstein, S -- Moerman, E J -- Soeldner, J S -- Gleason, R E -- Barnett, D M -- New York, N.Y. -- Science. 1978 Feb 17;199(4330):781-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/622567" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adolescent ; Adult ; Aged ; *Aging ; Cell Division ; Cell Survival ; Cells, Cultured ; Diabetes Mellitus/pathology/*physiopathology ; Fibroblasts/*cytology/pathology ; Humans ; Middle Aged ; Prediabetic State/pathology/*physiopathology ; Regression Analysis ; Skin/cytology/pathology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
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    Macroeconomics of disease prevention in the United States (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-06-09
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gori, G B -- Richter, B J -- New York, N.Y. -- Science. 1978 Jun 9;200(4346):1124-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/653358" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adolescent ; Adult ; Age Factors ; Aged ; Child ; Child, Preschool ; Costs and Cost Analysis ; Environment ; Female ; Government ; Humans ; Infant ; Life Expectancy ; Male ; Middle Aged ; Population Dynamics ; *Preventive Medicine ; Social Security ; Socioeconomic Factors ; United States
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
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    Melatonin content of the human pineal gland (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1978-01-06
    Beschreibung: Gas chromatography with electron capture detection was used to quantitate melatonin in single human pineal glands. The sensitivity of this melatonin assay is in the low picogram range. A 24-hour rhythm of pineal melatonin content was observed.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Greiner, A C -- Chan, S C -- New York, N.Y. -- Science. 1978 Jan 6;199(4324):83-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉North Lawn Unit, Riverview Hospital, Essondale, British Columbia, Canada.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17569491" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Adult ; Aged ; Aged, 80 and over ; Chromatography, Gas ; Female ; Gas Chromatography-Mass Spectrometry ; Humans ; Male ; Melatonin/analogs & derivatives/*analysis ; Middle Aged ; Pineal Gland/*chemistry
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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