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  • Development
  • Springer  (12)
  • Periodicals Archive Online (PAO)
  • 1995-1999
  • 1980-1984
  • 1975-1979  (12)
  • 1925-1929
  • 1977  (12)
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Publisher
  • Springer  (12)
  • Periodicals Archive Online (PAO)
Years
  • 1995-1999
  • 1980-1984
  • 1975-1979  (12)
  • 1925-1929
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  • 1
    ISSN: 1432-1432
    Keywords: 5S RNA ; Drosophila ; Evolution ; Secondary structure ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The nucleotide sequence ofDrosophila melanogaster 5S RNA has been determined and appears to be homogeneous both in the KC cell line and in the insect at different developmental stages. Experimental evidence on the conformation of this molecule is in agreement with a general class of 5S RNA models.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 182 (1977), S. 107-116 
    ISSN: 1432-041X
    Keywords: Drosophila ; Salivary glands ; Ecdysone ; Transcriptional control ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Injection of α-ecdysone into the larval haemolymph of late third instar larvae ofD. virilis induces both the extrusion of secretory proteins and the inactivation of the enzyme glutamine-fructose-6-phosphate-aminotransferase (E.C. 2.6.16) in the salivary glands. In the presence of actinomycin D or cycloheximide the hormone is ineffective. If before adding these inhibitors RNA synthesis is allowed to proceed for 1.5h, or protein synthesis for 2h after ecdysone injection, however, the protein extrusion and the enzyme inactivation do occur. It is proposed that ecdysone controls these two cytoplasmic events at the transcriptional level by the activation of specific Correlations with puff activities are discussed.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 183 (1977), S. 325-335 
    ISSN: 1432-041X
    Keywords: Gangliosides ; Sialoglycoproteins ; Acetylcholinesterase ; Brain ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The developmental accretion of up to nine individual gangliosides in foetal brains, peri- and postnatal cortices, postnatal cerebelli and olfactory lobes and in the liver and the spleen were investigated in mice and compared with that of glycoprotein-bound sialic acid and the activity of the acetylcholinesterase. In foetal brain and in postnatal liver and spleen more sialic acid was found bound to glycoproteins than to gangliosides. In postnatal brain structures, however, ganglioside-NeuAc predominated and increased between the 7th and 21st d about 2-fold in the olfactory lobes and cerebellum and more than 3-fold in the cortex. During foetal development the relative quantities (mol %) as well as the absolute concentrations (compared with the fresh weight) of GM1, GM2 and GM3 in the brain decreased, whereas those of GD1a, GD1b and GQ increased. This pattern change continued perinatally in the cortex up to the end of the first week. Thereafter the pattern changed little, but the concentration of all gangliosides present increased much more rapidly, especially between the 10th and 13th d. The postnatal cerebellum and olfactory lobes contained higher concentrations of GM1 and GM3 than the cortex, both gangliosides decreasing in favour of their di-, tri- and tetrasialo-homologues during the third postnatal week. In all brains structures the accretion of GD1a and GT1 was proportional to the increase in the activity of the acetylcholinesterase. Unlike the brain structures, the ganglioside pattern in the liver and spleen, characterised by a predominance of monosialogangliosides and of GD3, did not change noticeably during the first three weeks after birth. The coincidence of the changes in ganglioside accretion observed in the different brain structures with successive periods of morphological differentiation further support the suggestion that gangliosides may play an important role in control of the growth and differentiation of developing nerve cells.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 182 (1977), S. 329-346 
    ISSN: 1432-041X
    Keywords: Porifera ; Spongillides ; Gemmula ; Development ; Cell differentiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung Die beschalten Dauerstadien (Gemmulae) des SüßwasserschwammesEphydatia fluviatilis enthalten uniforme, totipotente Statocyten (Thésocyten), aus denen sich im Keimungsverlauf Archaeocyten (ein- und zweikernige) und Histoblasten differenzieren. Letztere treten nach einem gewissen Inkubationszeitraum in der zapfenartigen Zone unter der Mikropyle auf, während sich die übrigen Zelltypen zu einem an der Schalenöffnung orientierten, dreidimensionalen Muster gefälleartig anordnen. Nach Ausbildung eines einschichtigen Pinacocyten-Epithels (primäres Pinacoderm) aus peripher gelegenen, einkernigen Zellen schlüpft das nunmehr im Kapselinneren entstandene Primordium durch die offene Mikropyle und nimmt mit dem Substrat Verbindung auf. Das Primordium entwickelt sich zum frühen Jungschwamm, in den die restlichen Archaeocyten, Histoblasten und auch vereinzelt Skleroblasten einwandern.
    Notes: Summary The dormant shelled gemmulae of the fresh water spongeEphydatia fluviatilis contain uniform, totipotent statocytes (thésocytes), which can differentiate either into archaeocytes (mono- and binucleated) or into histoblasts. The histoblasts accumulate at the villus near the micropyle. The other cell types orientate in a three-dimensional pattern at the micropyle, according to a developing gradient. After the primary pinacoderm is formed, the sponge primordium is released through the open micropyle. The primordium develops into a new sponge, into which archaeocytes, histoblasts and scleroblasts migrate.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 181 (1977), S. 227-245 
    ISSN: 1432-041X
    Keywords: Compound eye ; Development ; Cell lineages ; Genetic mosaics ; Drosophila
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The generalogical relationships of photoreceptor cells within the compound eye ofDrosophila have been studied using cell labelling, with either3H-thymidine or recessive mutations, during the third larval stage. It has been found that photoreceptor and secondary pigment cells arise from different precursor cells. Under the present experimental conditions, precursors of receptor cells give rise to about 8 elements which differentiate as R cells of two different groups. One of the cells differentiates as R7 and the remaining as any one of the R1 to R6. The last cells behave initially as equivalent, and can differentiate within the same or within different, but neighbouring, ommatidia. The class of R1 to R6 cell in which each one of these elements differentiates, seems to depend on the time of its origin. The implications of these findings for the formation of the ommatidial pattern are discussed.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 113 (1977), S. 309-313 
    ISSN: 1432-072X
    Keywords: Cellulose enzyme system ; Development ; Acanthamoeba
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung In Extrakten wachsender Kulturen von Acanthamoeba castellanii konnte ein cellulose-abbauendes Enzymsystem nachgewiesen werden. Es besteht aus einer reduzierende Zucker abspaltenden Komponente mit einem pH-Optimum bei 4, einer viscositätsverändernden Komponente mit einem pH-Optimum bei 6 und einer β-Glucosidase mit einem pH-Optimum von 3,5. Bei pH 4 sind die Celluloseabbauprodukte Cellobiose und Glucose, bei pH 6 höhermolekulare Oligosaccharide. Während der Entwicklung in einem nährstofffreien Salzmedium nehmen die Cellulaseaktivitäten ab: Vor dem Start der Cellulosesynthese sind noch etwa 30% der ursprünglich vorhandenen Celluloseaktivität nachzuweisen, fertige Cysten besitzen noch etwa 10% der Aktivität. Die Bedeutung des Cellulassenzymsystems wird ausgehend von der Tatsache diskutiert, daß die Excystierung ohne Abbau der Cystenwand, in die die Cellulose eingelagert ist, stattfindet.
    Notes: Abstract It could be shown that extracts of growing cultures of Acanthamoeba castellanii contained a cellulose degrading system. Reducing sugars are split off by one component of this system at an optimum of pH 4, another enzyme changes the viscosity at an optimum of pH 6, and a third component is a β-glucosidase with an optimum at pH 3.5. At pH 4 the cellulose degradation products are cellobiose and glucose; at pH 6 higher molecular weight oligosaccharides are produced. During the development from trophozoites to cysts in a nutrient-free medium, the activities of both cellulases decline: Prior to the start of cellulose synthesis only 30%, and in cysts only 10% of the original existing activities are detectable. The biological function of the cellulase enzyme system is discussed together with a consideration of the fact that excystment takes place without digestion of the cyst wall in which the cellulose is deposited.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 114 (1977), S. 123-136 
    ISSN: 1432-072X
    Keywords: Fungus ; Cytochemistry ; Microbodies ; Development ; Entophlyctis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Ultrastructural localization of peroxidatic activity was investigated in the chytrid Entophlyctis variabilis with the 3,3′-diaminobenzidine (DAB) cytochemical prodedure. The subcellular distribution of reaction product varied with changes in pH of the DAB medium and with the developmental stage of the fungus. Incubations in the DAB reaction medium at pH 9.2 produced an electron dense reaction product within single membrane bounded organelles which resembled microbodies but which varied in shapes from elongate to oval. At this pH the cell wall also stained darkly. When the pH of the DAB medium was lowered to pH 8.2 or 7.0, DAB oxidation product was localized within mitochondrial cristae as well as in microbodies and zoosporangial walls. As soon as zoospores were completely cleaved out of the zoosporangial cytoplasm, endoplasmic reticulum (ER) also stained. When the wall appeared around the encysted zoospore, ER staining was no longer found. The influence of the catalase inhibitor, aminotriazole, and the inhibitors of heme enzymes, sodium azide and sodium cyanide, on the staining patterns within cells incubated in the DAB media indicates that microbody staining is due to both catalase and peroxidase, mitochondrial staining is due to cytochrome c, and ER staining is due to peroxidase.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 176 (1977), S. 167-178 
    ISSN: 1432-0878
    Keywords: Intestine (rat) ; Development ; Isolated cells ; Enzymes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A modification of Weiser's (1973) cell isolation method was used in order to study the developmental pattern of various intestinal enzyme activities in villus and crypt cells of normal rats from 5 days after birth until 8 weeks. Alkaline phosphatase and enterokinase activities were always located in the upper villus zone during postnatal development. Enterokinase activity was higher in the upper villus cells during the third week of life than after this period. Aminopeptidase activity was located in the crypt cells during the first week, its maximum activity remained in this area until the third week. At this time, sucrase activity appeared in the crypt cells, then aminopeptidase and sucrase activities rose to the villus zone during the fourth week. Amylase activity was detected along the entire crypt-villus axis 5 days after birth, reaching maximum activity in crypt cells at the end of the first week and in the upper villus cells after the fourth week. In contrast with the other enzymes studied almost all amylase activity was soluble in the youngest animals whereas at weaning most of the activity appeared in a particulate form in the villus cells. But in the crypt cells the ratio between particulate and soluble form remained unchanged until the adult stage. Various hypotheses are advanced to explain the patterns of evolution of the different enzymes.
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  • 9
    ISSN: 1573-5133
    Keywords: Embryology ; Development ; Embryonic respiration ; Carotenoids in respiration ; Evolution ; Egg hiding ; Mouth brooder ; Young size ; Cichlids ; Mouth fertilization ; Size on release ; Latimeria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis With yolk as a food source, development of Labeotropheus takes place in the buccal pouch of the female until such time as juveniles are formed. Hatching from the vitelline membrane occurs early, after 6 days of incubation, and the eleutheroembryo develops without metamorphic stages directly into a juvenile, forming advanced structures like fins, skeleton and pigments, at a time when a large yolksac is still present. A strong circulatory network on the yolk and anal fin fold, and a yellow carotenoid pigment provide the oxygen supply within the closely packed buccal pouch. A relatively large self-sufficient juvenile, 14% of the adult fish size, is released from the mother's mouth 31 days after fertilization. The evolution of advanced hiding styles in reproductive guilds of fishes is discussed and ends with a speculation that the Latimeria, having had more geological time to refine its hiding style, releases fully developed young, 25 to 30% the size of the adult fish. The advanced style of hiding eggs is accompanied not only with fewer, larger eggs, but also by a successive increase in yolk density in terms of nutrients and respiratory pigments; these in effect determine the size of the released juvenile.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 180 (1977), S. 211-222 
    ISSN: 1432-0878
    Keywords: Muscles ; Enzymes ; Chicken ; Nerve ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. The development of the characteristic histochemical appearance of the slow anterior latissimus dorsi (ALD) and fast posterior latissimus dorsi (PLD) was studied in chickens during embryonic development as well as during regeneration of minced muscle. 2. During embryonic development the activity of the oxidative enzyme succinic dehydrogenase (SDH) is higher in the slow ALD muscle already at 16 days of incubation. At this time the fast PLD has a higher activity of the glycolytic enzyme, phosphorylase. Although the histochemical appearance of the two types of muscle is already different at 16 days, their contractile speeds are still similar. No difference in myosin ATP-ase was found in the two muscles in young embryos but in 20-day old embryos the two muscles became distinctly different when stained for this enzyme. 3. When PLD muscles in hatched chickens redeveloped during regeneration in place of ALD the histochemical characteristics of the regenerated muscle resembled ALD, and when ALD regenerated in place of PLD it resembled PLD. 4. It is concluded that the histochemical characteristics of slow and fast muscles become determined during early development, even before any difference in contractile properties can be detected and that they are determined by the nerve.
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  • 11
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 181 (1977), S. 427-441 
    ISSN: 1432-0878
    Keywords: Chick embryo ; Choroid epithelium ; Junctional complex ; Development ; Freeze-etching
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The Junctional complex of choroid epithelial cells was studied during in vivo formation, disaggregation after trypsin treatment, and in vitro reaggregation. The in vivo formation begins with the occurrence of amorphous patches of particles followed by the formation of small particulate rows and polygonal-ordered particle assemblies. Further arrangement of the zonula occludens continues with the confluence of particles and smooth contoured ridges. At the 9th day stage a fully developed zonula occludens has developed. In a subsequent step nexus become integrated within the tight junction formation. Disaggregation after trypsination results in fragmentation of the zonulae occludentes. Parts of the disassembling aggregates become incorporated in vacuoles indicating an endocytotic mode of “digestion”. The in vitro reconstruction of the zonula occludens proceeds from remnants of the former zonula occludens. On the 3rd to 4th day of cultivation mature tight junctions are visible. In vitro integrations of nexus were observed during a later phase. On the 7th day, cultivated choroid epithelial cells reveal well differentiated Junctional complexes consisting of continuous zonulae occludentes and integrated gap junctions.
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  • 12
    ISSN: 1432-0878
    Keywords: GEP-system ; Small intestine ; Human embryo ; Neurotensin ; Development ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The endocrine gastro-entero-pancreatic (GEP) system of 10 human embryos was studied with special reference to neurotensin-immunoreactive cells. These cells are first present in the ileal and jejunal mucosa of 12 to 13 week old embryos. Thereafter the neurotensin-immunoreactive cells are found regularly in these segments of the gut with an increasing number towards the terminal ileum. At about the twentieth week of gestation, the neurotensin cells are detected also in the lower duodenum, i.e. the distribution pattern is more extensive in this age than in younger embryos or in adults.
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