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  • liver  (13)
  • evolution
  • nitrogen
  • Springer  (23)
  • 1980-1984
  • 1975-1979  (23)
  • 1976  (23)
Collection
Keywords
Publisher
  • Springer  (23)
Years
  • 1980-1984
  • 1975-1979  (23)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Gene action in fish of tetraploid origin. III. Ribosomal DNA amount in cyprinid fish (1976)
    Springer
    Biochemical genetics 14 (1976), S. 19-26 
    Details
    ISSN: 1573-4927
    Keywords: evolution ; polyploidy ; ribosomal RNA genes ; cyprinid fish
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Phylogenetically diploid and tetraploid cyprinid fish species have cells of very similar volumes and protein contents. This finding has prompted us to postulate a regulatory system established during the evolution of the tetraploids leading to a diploid state of genic expression. It was proposed that this might be accounted for by a selective loss of ribosomal genes. RNA-DNA hybridization experiments, however, reveal a clear-cut 1:2 relationship of ribosomal DNA amounts between the diploid and the tetraploid species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00484870
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  • 2
    Electronic Resource
    Electronic Resource
    Gene action in fish of tetraploid origin. V. Cellular RNA and protein content and enzyme activities in cyprinid, clupeoid, and salmonoid species (1976)
    Springer
    Biochemical genetics 14 (1976), S. 975-980 
    Details
    ISSN: 1573-4927
    Keywords: evolution ; polyploidy ; RNA content ; protein content ; enzyme activities ; Cyprinidae ; Isospondyli
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The ratio of cellular RNA and protein content is about 1:1 between phylogenetically diploid and tetraploid species of the teleost family Cyprinidae, but is roughly in proportion to ploidy in species of the teleost order Isospondyli. Enzyme activities do not unequivocally comply with this scheme. These findings are discussed in view of the hypothesis that a regulatory mechanism which reduces genic activity has evolved in the tetraploid cyprinids but not in the tetraploid species of the order Isospondyli.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00485129
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  • 3
    Electronic Resource
    Electronic Resource
    Developmental specificity and evolution of the acid phosphatase isozymes of Triticum aestivum and its progenitor species (1976)
    Springer
    Biochemical genetics 14 (1976), S. 595-609 
    Details
    ISSN: 1573-4927
    Keywords: Triticum ; acid phosphatase ; isozymes ; developmental genetics ; evolution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The tissue and developmental specificities of the acid phosphatase (ACPH) isozymes of Triticum aestivum and its progenitor species T. turgidum and T. tauschii have been determined and compared using the zymogram technique. Tissue and/or developmental variation in relative staining intensity, suggestive of variation in the quantity of active enzyme present, was observed for each of the seven major isozymes expressed. Isozymes homologous to each of the major isozymes of the hexaploid were detected in one or the other of the progenitor species. No difference in the pattern of developmental or tissue specificity was observed between the species for any isozyme. However, ACPH-4, encoded by Acph4, a structural gene linked to chromosome 4A, differs in electrophoretic mobility between T. aestivum and T. turgidum, indicating that divergence has occurred between these species at the Acph4 locus since the origin of the hexaploid. The molecular weight of each of five ACPH isozymes of the hexaploid was determined to be approximately 58,000. This finding, plus the results of the developmental study and the earlier demonstration that the structural genes for six isozymes (including four of those whose molecular weight was determined) are linked to homoeologous chromosomes, provides evidence in support of the suggestion that the ACPH structural genes of hexaploid wheat are homoeologously related.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00485838
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  • 4
    Electronic Resource
    Electronic Resource
    Gene action in fish of tetraploid origin. IV. Ribosomal DNA amount in clupeoid and salmonoid fish (1976)
    Springer
    Biochemical genetics 14 (1976), S. 293-297 
    Details
    ISSN: 1573-4927
    Keywords: evolution ; polyploidy ; ribosomal RNA genes ; Isospondyli
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Phylogenetically tetraploid species of the fish order Isospondyli generally have twice the mean ribosomal gene content as closely related species on the phylogenetically diploid level. Considerable intraspecific variation of rDNA amount was observed. These findings are discussed in view of the hypothesis that selective loss of ribosomal genes may account for diminishing genic activity in phylogenetically tetraploid organisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00484768
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  • 5
    Electronic Resource
    Electronic Resource
    Numerical approaches to the species problem (1976)
    Springer
    Plant systematics and evolution 125 (1976), S. 179-187 
    Details
    ISSN: 1615-6110
    Keywords: Species problem ; numerical phenetics ; phenetic bottlenecks ; computers ; multivariate analyses ; geographic variation ; cladistics ; evolution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The use of numbers by systematists is not new. Measurements to describe individuals and formal taxa have been used since the beginnings of our science. But the advent of electronic computers now permits a much more accurate understanding of the phenotypic relationships within and among populations and taxa. Furthermore, estimates of cladistic relationship also are being attempted with the help of computers. Computers can increase our understanding of speciation, but this requires us to think intelligently about the meaning of their results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00986150
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  • 6
    Electronic Resource
    Electronic Resource
    Chemiluminescence of mouse liver after administration of a carcinogen (1976)
    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 1556-1557 
    Details
    ISSN: 1573-8221
    Keywords: liver ; chemiluminescence ; carcinogens
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Changes in the intensity of chemiluminescence of the liver were observed at different times after injection of 9,10-dimethyl-1,2-benzanthracene into mice. The possible connection between the observed phenomena and the formation and accumulation of the endogenous carcinogen in the liver is examined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00799810
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  • 7
    Electronic Resource
    Electronic Resource
    Changes in the structure of chromatin in hepatocyte nuclei of rats adapted to hypoxia (1976)
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 445-448 
    Details
    ISSN: 1573-8221
    Keywords: hypoxia ; liver ; structure of hepatocyte chromatin ; Acridine Orange ; microfluorometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The structure of chromatin in the nuclei of isolated surviving hepatocytes and of isolated hepatocyte nuclei was studied by fluorochroming with Acridine Orange and microfluorometry of the luminescence of chromatin-bound dye at 530 and 590 nm in intact rats and rats adapted to hypoxia in a pressure chamber for 60 days. Hepatocyte nuclei of intact rats were shown to be distributed on the basis of their fluorescence at 530 nm into three classes, with a ratio between intensities of 1∶2∶4, whereas hepatocyte nuclei of rats adapted to hypoxia formed only one class, corresponding to the second class in the control. The ratio between the intensities of luminescence at 590 nm and 530 nm (the coefficient α) forms a normal distribution in intact rats, but in adapted rats it formed a bimodal distribution with a shaft of the maxima toward both sides of the control. During hypoxia repression of some genes and depression of others is considered to take place in the chromatin of liver nuclei.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00804945
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of carbon tetrachloride on RNA metabolism in the rat liver (1976)
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 677-680 
    Details
    ISSN: 1573-8221
    Keywords: carbon tetrachloride ; liver ; total, nuclear, and cytoplasmic RNA ; RNA turnover
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The effect of systematic administration of carbon tetrachloride (CCl4) to rats on the RNA content in the liver and the intensity of incorporation of the labeled precursor (uridine-H3) into it was investigated. Comparison of the results of morphological and biochemical studies revealed two consecutive stages of the toxic process, terminating in the formation of septal fibrosis. The sharpest changes in rapid RNA turnover in the rat liver were observed during the first 3 months of action of the toxic agent. The disturbance of metabolism also was reflected in a lowered RNA level and changes in the nucleo-cytoplasmic ratio in the tissue of the affected liver.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00797127
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  • 9
    Electronic Resource
    Electronic Resource
    Effect of disturbance of the innervation of the liver and loss of bile on biliary and hepatic enzyme activity (1976)
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 847-849 
    Details
    ISSN: 1573-8221
    Keywords: enzymes ; liver ; disturbance of innervation ; loss of bile
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Continuous loss of bile from rats with a bile reservoir connected to the common bile duct led to an increase in specific activity of malate, lactate, glutamate, and glucose-6-phosphate dehydrogenases, alkaline and acid phosphatases, urokinase, and histidase in liver homogenates by the seventh day. By the tenth day their specific activity had fallen. After disturbance of the innervation of the rats' livers the ATP concentration fell sharply and the specific activity of the above-mentioned enzymes in the liver was considerably inhibited. During continuous loss of bile, fluctuating changes took place in the specific activity of these enzymes and also of sorbitol dehydrogenase in the bile, starting from the first and continuing until the tenth day of the experiment. Support for the view that these fluctuations were under the control of the nervous system was given by the considerable changes in their character following disturbance of the hepatic innervation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00802999
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  • 10
    Electronic Resource
    Electronic Resource
    Content of adenyl mononucleotides and respiratory phosphorylation in mitochondria of rats with transplantable tumors (1976)
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 903-905 
    Details
    ISSN: 1573-8221
    Keywords: tumor growth ; oxidative phosphorylation ; ATPase ; adenyl mononucleotides ; liver
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The content of adenyl mononucleotides, the process of oxidative phosphorylation, and the ATPase activity of the liver mitochondria of rats with transplantable sarcoma 45 and Walker's carcinosarcoma were investigated at different stages of tumor growth. The fall in the ATP level observed in the liver mitochondria of the rats with tumors was due, first, to inhibition of its formation as a result of the partial uncoupling of oxidative phosphorylation and, second, to an increased rate of its breakdown as a result of increased ATPase activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00803019
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