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  • microcirculation  (13)
  • Springer  (13)
  • Madrid : Secc
  • 2005-2009
  • 1980-1984
  • 1975-1979  (13)
  • 1955-1959
  • 1976  (13)
Collection
Publisher
  • Springer  (13)
  • Madrid : Secc
Years
  • 2005-2009
  • 1980-1984
  • 1975-1979  (13)
  • 1955-1959
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 1770-1773 
    ISSN: 1573-8221
    Keywords: shock ; microcirculation ; retrobuccal pouch of hamsters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Substantial disturbances of the microcirculation in the mucous membrane of the retrobuccal pouch were observed in acute experiments on hamsters in which severe shock was induced by standardized mechanical trauma to the thigh. All the animals died within 24 h of such trauma. If the animals died not less than 1 h after trauma the microcirculatory changes were definitely phasic in character; in particular, a phase of temporary relative adaptation and stabilization of the peripheral circulation was observed in these animals, followed inevitably by a phase of decompensation and a terminal phase ending in death. In shock proceeding rapidly to a lethal termination within 1 h, no definite phasic pattern of the microcirculatory changes was observed, but all the indices worsened more or less rapidly. Unlike most other investigators, the authors saw no marked intravascular aggregation of red cells in these experiments.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 626-629 
    ISSN: 1573-8221
    Keywords: Venous stasis ; microcirculation ; synovial membranes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The state of the microcirculation of the synovial membranes in venous stasis was investigated in dogs. After ligation of the femoral vein disturbance of the blood flow leads to changes in the microcirculation in the synovial membranes and to congestion of the venules. Thinning of the capillary walls and the formation of swellings and protrusions are observed. The severity of the changes in the vessel wall depends on the caliber of the vessels. One month after ligation of the vein, the signs of stasis in the tissues of the articular capsule are reduced, indicating the development of a collateral venous circulation.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 796-798 
    ISSN: 1573-8221
    Keywords: vascular permeability ; microcirculation ; stress ; histamine ; mast cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Immobilization of rats for 1 or 3 h leads to an increase in vascular permeability for ink particles and disturbances of the microcirculation in the mesenteric microvessels (formation of aggregates, appearance of “plasmatic vessels,” closure of arteriolar-venular shunts). An important role in the pathogeneis of these changes is played by histamine liberated from the mast cells without their undergoing degranulation. Liberation of histamine may be the trigger mechanism in the development of disturbances of vascular permeability during prolonged immobilization stress.
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  • 4
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    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 982-984 
    ISSN: 1573-8221
    Keywords: burn shock ; toxemia ; microcirculation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Acute experiments on rats showed that repeated extensive burns inflicted on animals convalescing from previous burns are tolerated better, do not cause death, and are accompanied by moderate changes in the microcirculation. Similar burns in intact rats lead to severe, lethal shock, intravascular aggregation of erythrocytes, and substantial disturbances of the microcirculation, so that tissue nutrition is impaired. It is postulated that these results could be indirect evidence that toxemia plays an essential role in the genesis of intravascul aggregation of erythrocytes in burns.
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  • 5
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    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 33-35 
    ISSN: 1573-8221
    Keywords: microcirculation ; gas exchange ; acid-base balance ; organophosphorus cholinesterase inhibitors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A quantitative study of the microcirculation based on certain indices of the gas exchange and acid-base balance of the blood was carried out in rats and rabbits during poisoning by compound GA-70, an organophosphorus cholinesterase inhibitor with peripheral action. Comparison of the findings shows that a disturbance of the microcirculation plays the leading role in the development of hypoxia during GA-70 poisoning.
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  • 6
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    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 135-138 
    ISSN: 1573-8221
    Keywords: arterioles ; vasodilatation ; microcirculation ; effect of light
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Visible light, as usually used for intravital microscopy, causes dilatation of the arterioles of the denervated frog submaxillary muscle. The minimal effective intensity of illumination of the object was 15 lx. The degree of dilatation of the arterioles in response to maximal intensity of light (250 lx) was inversely proportional to the initial diameter of the vessel. Arterioles 20–40 μ in diameter differed in their reactivity depending on the thickness of their walls. Highly reactive arterioles have thick walls. Their diameters were doubled or moreby illumination with visible light. Photic vasodilatation is reversible.
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  • 7
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    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 310-312 
    ISSN: 1573-8221
    Keywords: burns ; burn toxin ; microcirculation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Toxin for burned rat skin, purified immunochemically, possesses definite physiological activity against the cardiovascular system of homologous animals. If injected into the blood stream, the toxin lowers the systemic arterial pressure within 2 h from 125±7 to 74±8 mm Hg. The development of systemic hypotension is accompanied by secondary disorders of the microcirculation in the mesentery of the small intestine, characterized by constriction of the arterioles, slowing of the blood flow along the venules, and reduction of the capillary blood flow.
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  • 8
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    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 313-315 
    ISSN: 1573-8221
    Keywords: microcirculation ; hypoxic hypoxia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Hypoxia was induced in rats by administration of a gas mixture corresponding to the composition of the atmosphere at an altitude of 6000 m above sea level. Mesenteric arteries and veins measuring from 9 to 43 μ in diameter were studied. Their diameter and the pressure and velocity of the blood flow in them were measured. The arterial microvessels were dilated in hypoxia. Their diameter was increased by the greatest amount (by 3–5 μ) during the first 3–5 min of administration of the gas mixture. The blood pressure and velocity of blood flow in these vessels were reduced throughout the experiment.
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  • 9
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    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 289-291 
    ISSN: 1573-8221
    Keywords: microcirculation ; bradykinin ; split-image method ; application of drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Responses of the mesenteric microvessels of rats to application and intravenous injection of bradykinin were studied in acute experiments using intravital microscopy. No clear bioelectric response of the smooth-muscle cells of the microvessels to local application of bradykinin could be found in electrophysiological experiments. In another series of experiments the dynamics of vasomotor activity were studied after the same treatment by the split-image method. The response of the microvessels to bradykinin application was shown to vary in character depending principally on whether the preparation was being applied for the first or subsequent time. It is suggested that bradykinin acts on the mesenteric microvessels through the intermediary of other vasoactive substances.
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  • 10
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    Bulletin of experimental biology and medicine 81 (1976), S. 292-294 
    ISSN: 1573-8221
    Keywords: small intestine ; microcirculation ; motor activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Experiments on guinea pigs, rabbits, and rats with simultaneous recording of motor activity of the small intestine and the state of its microcirculation showed that the diameter of the intramural vessels of the intestine depends on its contractile activity. On the basis of their data the authors suggest an explanation for the mechanism of disturbance of the secretory and absorptive function of the small intestine after blocking of its nervous reflexes and transplantation.
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  • 11
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    Bulletin of experimental biology and medicine 81 (1976), S. 146-148 
    ISSN: 1573-8221
    Keywords: microcirculation ; reactivity of arterioles ; vasoactive substances
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Reactivity of mesenteric arterioles 10–30 μ in diameter to application of histamine (100–500 μg) adrenalin, and noradrenalin (1–10 μg) was studied in rats with experimental renal and hormonal hypertension. The sensitivity of the microvessels to the vasoactive substances was shown to vary with the stage of development of experimental hypertension.
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  • 12
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    Bulletin of experimental biology and medicine 81 (1976), S. 19-22 
    ISSN: 1573-8221
    Keywords: microcirculation ; vascular permeability ; hemmorrhage ; thrombus formation ; lasers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Responses of venules, capillaries, arterioles, and mast cells of the rat mesentery to irradiation by the LGI-21 pulsed ultraviolet laser (λ=337 nm) was studied by intravital microscopy. The diameter of the laser beam varied from 2 to 100 μ. The processes studied were recorded and analyzed by a photographic and videorecording method. Depending on the intensity and duration, irradiation caused either an increase in permeability of the vessel walls, or thrombus formation, or hemorrhage. Besides injury to the vessel wall, an important role in thrombus formation was played by factors appearing on destruction of erythrocytes and other blood cells. The change in diameter and permeability of the vessels during laser irradiation of the mast cells could be associated with liberation of the histamine and serotonin contained in them.
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  • 13
    Electronic Resource
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    Bulletin of experimental biology and medicine 81 (1976), S. 357-359 
    ISSN: 1573-8221
    Keywords: microcirculation ; mesentery ; velocity of blood flow ; resistance to blood flow ; architectonics of the vascular system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The blood-flow distribution was studied in 49 bifurcations of arterial trunks 25.7 μ in diameter into branches 0.9 μ in diameter in the mesentery ofR. temporaria. The flow was calculated as the product of the linear velocity of blood flow and the area of cross-section of the vessel. The linear velocity was measured by impulse digital chronometry of the erythrocyte transit time, and the geometry of the bifurcation was studied in intravital photographs. The asymmetrical structure of the bifurcation was established: One branch had a lumen 2.2 times greater than the other, and a smaller angle of turn (29° and 59°). The flow into branch I was 3 times greater than the flow into branch II, as the result of its larger lumen and the greater linear velocity of the blood flow. According to calculations, the specific resistance of turn of the branch was negligible compared with the total resistance to its blood flow; hence it follows that the angle of turn of the branches is not an important regulator of the blood volume flowing through it. The correlation found experimentally between the blood flow in the branches, their radius, and their angle of turn is well described by equations of an “optimal” model of vascular ramification.
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