ISSN:
1573-8221
Keywords:
enzymes
;
liver
;
disturbance of innervation
;
loss of bile
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Continuous loss of bile from rats with a bile reservoir connected to the common bile duct led to an increase in specific activity of malate, lactate, glutamate, and glucose-6-phosphate dehydrogenases, alkaline and acid phosphatases, urokinase, and histidase in liver homogenates by the seventh day. By the tenth day their specific activity had fallen. After disturbance of the innervation of the rats' livers the ATP concentration fell sharply and the specific activity of the above-mentioned enzymes in the liver was considerably inhibited. During continuous loss of bile, fluctuating changes took place in the specific activity of these enzymes and also of sorbitol dehydrogenase in the bile, starting from the first and continuing until the tenth day of the experiment. Support for the view that these fluctuations were under the control of the nervous system was given by the considerable changes in their character following disturbance of the hepatic innervation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00802999
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