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  • Articles  (22)
  • hypothalamus  (22)
  • Springer  (22)
  • American Institute of Physics
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  • Oxford University Press
  • 2010-2014
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  • 1985-1989
  • 1975-1979  (22)
  • 1945-1949
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  • 1978  (11)
  • 1976  (11)
  • Biology  (22)
  • Nature of Science, Research, Systems of Higher Education, Museum Science
  • Electrical Engineering, Measurement and Control Technology
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  • Articles  (22)
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Keywords
Publisher
  • Springer  (22)
  • American Institute of Physics
  • Cell Press
  • Oxford University Press
Years
  • 2010-2014
  • 2005-2009
  • 1985-1989
  • 1975-1979  (22)
  • 1945-1949
Year
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  • Biology  (22)
  • Nature of Science, Research, Systems of Higher Education, Museum Science
  • Electrical Engineering, Measurement and Control Technology
  • Medicine  (22)
  • 1
    Electronic Resource
    Electronic Resource
    Effect of low-molecular-weight extracts of heterologous thymus and pineal glands and hypothalamus on the immune response in mice (1976)
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 218-220 
    Details
    ISSN: 1573-8221
    Keywords: immunogenesis ; thymus ; pineal gland ; hypothalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The effect of acetic acid extracts of the bovine thymus and pineal glands and hypothalamus, purified by gel filtration, on the content of circulating antibodies and the number of antibody-forming cells was investigated in experiments on mice. Extracts of the thymus and pineal glands, injected for 10 days, stimulated immunogenesis induced by injection of sheep's red cells, whereas the hypothalamic extract had an inhibitory action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00801076
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  • 2
    Electronic Resource
    Electronic Resource
    Role of interoceptive impulses in the modulation of emotional and behavioral responses (1976)
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 295-298 
    Details
    ISSN: 1573-8221
    Keywords: interoceptive impulses ; emotional behavior ; hypothalamus ; limbic system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Chronic experiments on rabbits with a gastric fistula and electrodes implanted into deep brain structures showed that stimulation of the gastric receptors leads to modulation of emotional and behavioral responses evoked by electrical stimulation of the hypothalamus, amygdala, and hippocampus. The effect depends on the intensity of interoceptive stimulation and on nature of the emotional response, which has its own cerebral control systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00804899
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of encephalectomy on corticosterone content in the fetal rat adrenals (1976)
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 744-745 
    Details
    ISSN: 1573-8221
    Keywords: rat fetuses ; hypothalamus ; adrenals ; corticosterone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The functional state of the pituitary-adrenal system was studied after removal of the hypothalamus from rat fetuses (encephalectomy in utero). Hormonal activity of the adrenal glands was estimated by fluorometric determination of their corticosterone content. Removal of the hypothalamus in fetuses aged 18.5–19.5 days lowered the adrenal corticosterone level. Injection of a homogenate of the hypothalamus into the fetuses immediately after encephalectomy prevented this decrease. The results confirm the presence of a functional link between the hypothalamus and the pituitary-adrenal system in rat fetuses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00797151
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  • 4
    Electronic Resource
    Electronic Resource
    Electroencephalographic changes in hypo- and hypertensive responses to hypothalamic stimulation (1976)
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 659-662 
    Details
    ISSN: 1573-8221
    Keywords: blood pressure ; hypothalamus ; monoamine oxidase inhibitor vetrazin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Changes in cortical and subcortical electrical activity during hypo- and hypertensive vascular responses to electrical stimulation of the hypothalamus were investigated before and after injection of the monoamine oxidase inhibitor vetrazin, in experiments on rabbits anesthetized with urethane. Vetrazin completely blocked the hypertensive response and its electroencephalographic manifestation but had no effect on hypotensive hypothalamic responses. The results are interpreted from the standpoint of differences in the neurochemical mechanisms of hypothalamic pressor and depressor responses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00797120
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  • 5
    Electronic Resource
    Electronic Resource
    Adrenocortical function during traumatic shock in rats after removal or deafferentation of the hypothalamus (1976)
    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 970-972 
    Details
    ISSN: 1573-8221
    Keywords: corticosterone ; shock ; hypothalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The 11-hydroxycorticosteroid (11-HCS) concentration was determined in the blood plasma of rats undergoing a mock operation, and rats with an intact, extirpated, or deafferented medio-basal hypothalamus (MBH), during traumatic shock. No significant differences were found in the basal 11-HCS level in the rats of the different groups. Removal of MBH led to a decrease in weight of the adrenal and pituitary glands, whereas deafferentation of MBH led to an increase in weight of the adrenals. The 11-HCS level in rats with complete deafferentation of MBH was significantly higher than in the animals undergoing the mock operation when both were in a state of traumatic shock.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00789842
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  • 6
    Electronic Resource
    Electronic Resource
    Serotonin concentration in the hypothalamus during changes in pituitary thyrotropic function (1976)
    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 955-956 
    Details
    ISSN: 1573-8221
    Keywords: serotonin ; hypothalamus ; pituitary thyrotropic function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The serotonin concentration in the hypothalamus was determined in sexually mature male rabbits during changes in pituitary thyrotropic function. No clear parallel was observed between the intensity of the pituitary thyrotropic function and the hypothalamic serotonin concentration. Stimulation of pituitary thyrotropic function by injection of 6-methylthiouracil or by partial thyroidectomy was accompanied by an increase in the serotonin concentration, whereas during aseptic inflammation in the thyroid gland or after a combination of removal of the superior cervical sympathetic ganglia and administration of chlorpromazine, the increase in thyrotropic function occurred without any significant changes in the hypothalamic serotonin concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00789836
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  • 7
    Electronic Resource
    Electronic Resource
    Effect of some tropane derivatives on noradrenalin uptake by synaptic vesicles of the hypothalamus (1976)
    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 1020-1022 
    Details
    ISSN: 1573-8221
    Keywords: tropane derivatives ; hypothalamus ; synaptic vesicles ; noradrenalin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The effect of some tropane derivatives on the uptake of exogenous noradrenlin was studied in experiments on isolated hypothalamic synaptic vesicles. LK-11, in a concentration of 1·10−5 M, like cocaine, inhibits the passive uptake of noradrenalin. This effect was shown to depend on the concentration of mediator in the incubation medium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00789858
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  • 8
    Electronic Resource
    Electronic Resource
    Mechanism of mesencephalic reticular influences on the hypothalamicpituitary-thyroid system (1976)
    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 1138-1142 
    Details
    ISSN: 1573-8221
    Keywords: Reticular formation ; hypothalamus ; thyroxine ; thyroid function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The role of the posterior hypothalamic nucleus in the transmission of mesencephalic reticular influences on thyroid hormone secretion was studied. In response to stimulation of the mesencephalic reticular formation in anesthetized cats the concentration of iodine bound with plasma proteins was increased. After bilateral coagulation of the posterior hypothalamic nucleus this effect disappeared. The results confirm the hypothesis of the leading role of the posterior hypothalamic nucleus in stimulation of thyroid hormone secretion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00785537
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  • 9
    Electronic Resource
    Electronic Resource
    Effect of neonatal androgenization on hypothalamic biogenic monoamines and pituitary function in rats (1976)
    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 1393-1395 
    Details
    ISSN: 1573-8221
    Keywords: neonatal androgenization ; anovulatory sterility ; hypothalamus ; pituitary ; biogenic monoamines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Injection of testosterone propionate into female Wistar rats on the 2nd–4th day after birth did not change the serotonin concentration but sharply reduced the noradrenalin and dopamine conconcentrations in the hypothalamus of the animals at the age of 3.5 months. This was accompanied by an increase in the prolactin content in the adenohypophysis despite preservation of normal somatotropic activity. The results of this investigation point to a role of catecholamines in the pathogenesis of anovulatory sterility and give greater precision to modern views on the regulation of pituitary gonadotropic function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00799488
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  • 10
    Electronic Resource
    Electronic Resource
    Effect of electrical stimulation of the supraoptic region of the hypothalamus on lipid metabolism and the development of atherosclerosis (1978)
    Springer
    Bulletin of experimental biology and medicine 85 (1978), S. 721-724 
    Details
    ISSN: 1573-8221
    Keywords: hypothalamus ; coronary arteries ; electrical stimulation ; lipid metabolism ; atherosclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Electrical stimulation of the supraoptic region of the hypothalamus for 3 weeks in rabbits kept for 3–8 weeks on an atherogenic diet accelerates and intensifies the development of hypercholesteremia and lipoidosis of the coronary arteries and also the metabolic disturbances in the myocardial tissue. These last disturbances are expressed as a fall in the tissue noradrenalin and creatine phosphate concentration and an increase in the inorganic phosphorus and lactic acid concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00806146
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  • 11
    Electronic Resource
    Electronic Resource
    Role of the cholinergic and adrenergic systems of the hypothalamus in the regulation of pituitary adrenocorticotrophic function (1978)
    Springer
    Bulletin of experimental biology and medicine 85 (1978), S. 704-707 
    Details
    ISSN: 1573-8221
    Keywords: hypothalamus ; corticosteroids ; cholinergic and adrenergic systems
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract In experiments on male rats the activity of the pituitary-adrenal system was studied after electrolytic destruction of different parts of the hypothalamus. Pharmacological analysis demonstrated the irregular distribution of cholinergic and adrenergic systems controlling the secretion of ACTH and glucocorticoids in the hypothalamus. It is suggested that the cholinergic systems are located in the mammillary region, α-adrenergic systems in the region of the anterior or posterior hypothalamus, and β-adrenergic receptors in the region of the ventromedial nuclei of the hypothalamus. The latter perhaps play an inhibitory role.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00806141
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  • 12
    Electronic Resource
    Electronic Resource
    Changes in the protein content in hypothalamic neurons of neonatally castrated sexually mature male rats (1978)
    Springer
    Bulletin of experimental biology and medicine 86 (1978), S. 1503-1506 
    Details
    ISSN: 1573-8221
    Keywords: hypothalamus ; sexual differentiation of the brain ; neonatal castration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Changes in the protein content in neurons of the anterior and mediobasal hypothalamus of neonatally castrated sexually mature rats were demonstrated by an interferometric method. A considerable increase in the dry weight of the neurons was found in the medial preoptic region and the arcuate and ventromedial nuclei of the hypothalamus. The clearest changes were observed in the nuclei of these neurons. The results point to an influence of androgens in the period of sexual differentiation of the brain on hypothalamic structures responsible for the regulation of both the cyclic and the tonic secretion of gonadotropic hormones in sexually mature animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00800298
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  • 13
    Electronic Resource
    Electronic Resource
    Distribution of the adrenoblocking drug pyrroxan in albino rats (1976)
    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 1815-1816 
    Details
    ISSN: 1573-8221
    Keywords: adrenoblockers ; pyrroxan ; distribution ; hypothalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The distribution of the adrenoblocking drug pyrroxan in the blood plasma and organs of albino rats was investigated. Pyrroxan was shown to appear rapidly in the brain, liver, kidneys, and other organs and to accumulate selectively in the hypothalamus. The use of a spectrofluorometric method showed that unchanged pyrroxan molecules disappear from the plasma and organs in the course of 2 h. In studies with pyrroxan-14C, radioactivity was detected in the organs for 24 h, but in the plasma for several days, indicating the formation of metabolites of pyrroxan or its complexes with plasma proteins and with structural elements of the organs. The high effectiveness of pyrroxan in different forms of hypothalamic disturbances accompanied by symptoms of overexcitation of the sympathetic nervous system can be explained by its selective accumulation in the hypothalamus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00785704
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  • 14
    Electronic Resource
    Electronic Resource
    Characteristics of estradiol receptor system of the anterior hypothalamus and adenohypophysis in guinea pigs (1978)
    Springer
    Bulletin of experimental biology and medicine 85 (1978), S. 81-85 
    Details
    ISSN: 1573-8221
    Keywords: adenohypophysis ; hypothalamus ; physicochemical characteristics ; receptor system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The presence of a specific estradiol-receptor system (E2-R) with limited capacity and with a high degree of strength of formation of the E2-R complex was demonstrated in the cytosol of the adenohypophysis, and anterior hypothalamus of guinea pigs in experiments in vivo and in vitro. The physicochemical properties of the E2-R system of the adenohypophysis and anterior hypothalamus differ in certain parameters. The E2-R complexes of the cytosols of the adenohypophysis and anterior hypothalamus formed at different temperatures are not identical.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00801463
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  • 15
    Electronic Resource
    Electronic Resource
    Antibody-forming cells of the rat spleen after injury to the midbrain (1978)
    Springer
    Bulletin of experimental biology and medicine 85 (1978), S. 183-185 
    Details
    ISSN: 1573-8221
    Keywords: hypothalamus ; thalamus ; antibody-forming cells ; antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The number of plaque-forming cells (PFC) in the spleen of rats immunized with sheep's red blood cells (SRBC) after injury to the anterior or posterior part of the medial hypothalamus and also of the thalamus did not differ significantly from the number of PFC in the spleen of intact animals. The titers of hemolyzing and hemagglutinating antibodies in the animals with injuries to the midbrain were a little lower than in intact rats. The decrease in the quantity of circulating antibodies was not connected with the location of the foci of injury but was evidently a consequence of the craniocerebral trauma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00800120
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  • 16
    Electronic Resource
    Electronic Resource
    Dependence of androgenization on differentiation of the hypothalamic centers (1978)
    Springer
    Bulletin of experimental biology and medicine 85 (1978), S. 209-211 
    Details
    ISSN: 1573-8221
    Keywords: hypothalamus ; anovulatory cycle ; arcuate nucleus ; suprachiasmatic nucleus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Dependence of the sterilizing action of androgens on the level of differentiation of the hypothalamic centers in the postnatal period of development was studied in female rats. Asynchronous development of the arcuate nucleus (AN; the tonic center) and the suprachiasmatic nucleus (SCN; the cyclic center) was found. Neurons of AN begin to produce granules of secretion in 20-day embryos. The first neurons with granules of secretion are found in SCN in rats aged 5–7 days. Injection of testosterone propionate induces an anovulatory cycle in females during the first 7 days after birth, on account of inhibition of development of the hypothalamic cyclic center.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00800129
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  • 17
    Electronic Resource
    Electronic Resource
    Pattern of spread of excitation from the ventromedial hypothalamus to limbico-reticular brain structures (1978)
    Springer
    Bulletin of experimental biology and medicine 85 (1978), S. 418-421 
    Details
    ISSN: 1573-8221
    Keywords: hypothalamus ; limbico-reticular structures ; evoked potentials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The order of appearance of evoked potentials in different parts of the septum, amygdala, and reticular formation in response to gradually increasing stimulation of the ventromedial nucleus of the hypothalamus was studied. Excitation arising primarily in the ventromedial nuclei of the hypothalamus was shown to spread initially to structures of the septum and rostral reticular formation, and only later to the more caudal regions of the reticular formation and amygdala.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00801968
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  • 18
    Electronic Resource
    Electronic Resource
    Content of acid proteins in neuron and glial cell nuclei of the rat hypothalamus during cold adaptation (1978)
    Springer
    Bulletin of experimental biology and medicine 86 (1978), S. 1043-1045 
    Details
    ISSN: 1573-8221
    Keywords: adaptation ; cooling ; hypothalamus ; neuron and neuroglia ; acid proteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The content of acid proteins in nuclei of neurons and glial satellite cells in the medial preoptic region and supraoptic nucleus of the rat hypothalamus was studied by two-wave cytospectrophotometry on the 1st, 3rd, 7th, and 15th days of adaptation of the animal to cold (temperature 2–4°C). Cooling led to an initial decrease in the content of nuclear proteins in the whole neuronal-neuroglial system of the medial preoptic region, followed by gradual restoration to normal by the 15th day of cooling. In the glial cells of this region, before the return to normal there was a temporary increase in the content of acid proteins above the control level. In the neuronal-neuroglial system of the supraoptic nucleus a gradual accumulation of acid proteins was followed by a return to the control level. By the 15th day of the rats' stay in the cold, the content of neuronal and glial acid proteins of this nucleus fell somewhat below the control level.
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    URL: http://dx.doi.org/10.1007/BF00799585
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  • 19
    Electronic Resource
    Electronic Resource
    Age increase in the threshold of sensitivity of the tonic region of the hypothalamic sex center to inhibition by estradiol in female rats (1978)
    Springer
    Bulletin of experimental biology and medicine 86 (1978), S. 1090-1092 
    Details
    ISSN: 1573-8221
    Keywords: aging ; hypothalamus ; estradiol ; reproductive function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract To study the sensitivity of the hypothalamic sex center to the inhibitory action of estrogens, estradiol-17β was injected into the third ventricle of hemicastrated rats. The dose of estrogen needed to inhibit compensatory hypertrophy of the ovary by 50 and 100% in old animals (14–16 months) was 4 to 5 times greater than in young rats (3 months). The results point to an age increase in the threshold of sensitivity of the tonic region of the hypothalamic sex center to inhibition by estrogens and they can be used to explain the mechanisms of the age increase in gonadotropin secretion and the termination of reproductive function.
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    URL: http://dx.doi.org/10.1007/BF00799601
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  • 20
    Electronic Resource
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    Interaction between the hypothalamic-hypophyseal system and thyroid gland at different age periods (1978)
    Springer
    Bulletin of experimental biology and medicine 86 (1978), S. 981-984 
    Details
    ISSN: 1573-8221
    Keywords: hypothalamus ; pituitary ; deiodinating power ; thyroxine ; aging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Age differences in interaction between the hypothalamic-hypophyseal system and the thyroid gland were studied with consideration to both direct and feedback control. In old age significant disturbances affect both direct and feedback components of this system; the sensitivity of thyroid tissue to TSH and of the hypothalamus and pituitary to the action of T4 is increased. The increased sensitivity of the hypothalamic-hypophyseal system to T4 is largely determined by activation of the deiodination of T4 by the adenohypophysis. The reactivity of the thyroid gland and hypothalamic-hypophyseal complex to the corresponding factors is reduced.
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    URL: http://dx.doi.org/10.1007/BF00799567
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  • 21
    Electronic Resource
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    Effect of hydration and dehydration of animals on bioenergetics and mediator processes in neurosecretory cells of the anterior hypothalamus (1978)
    Springer
    Bulletin of experimental biology and medicine 86 (1978), S. 1666-1668 
    Details
    ISSN: 1573-8221
    Keywords: hypothalamus ; enzymes ; hydration ; dehydration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Histochemical methods were used to study the activity of oxidoreductases and enzymes inactivating mediators in the neurosecretory cells of the anterior hypothalamus during hydration and dehydration in rabbits. Enzymes of the Krebs cycle and of the electron transport system were shown to respond by increased activity to dehydration and by reduced activity to hydration. Activity of α-glycerophosphate dehydrogenase and glucose-6-phosphate dehydrogenase was increased compared with the control in both cases. Monoamine oxidase activity was reduced during dehydration but increased during hydration; changes in acetylcholinesterase activity were in the opposite direction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00801835
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  • 22
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    Effect of the enterotropic carcinogen 1,2-dimethylhydrazine on the hypothalamic biogenic amine level in rats (1976)
    Springer
    Bulletin of experimental biology and medicine 82 (1976), S. 1700-1702 
    Details
    ISSN: 1573-8221
    Keywords: 1,2-dimethylhydrazine ; biogenic amines ; hypothalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Subcutaneous injection of 1,2-dimethylhydrazine (DMH) in a dose of 21 mg/kg into male rats is followed after 24 h by a substantial fall in the hypothalamic levels of noradrenalin (NA), dopamine (DA), serotonin (5-HT), and 5-hydroxyindoleacetic acid (5-HIAA). During the first 3–12 h after injection of DMH the NA level was lowered and the intensity of 5-HT metabolism increased in the hypothalamus. The hypothalamic histamine level rose only 30 min after injection of the carcinogen. No significant change took place in the biogenic amine levels in the brain stem and cerebral hemispheres under the influence of DMH. It is suggested that an essential link in the mechanism of the carcinogenic action of DMH in rats is the hormonal metabolic disturbances caused by the selective action of DMH at the level of the hypothalamic biogenic amines.
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    URL: http://dx.doi.org/10.1007/BF00790390
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