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  • noradrenalin  (11)
  • Springer  (11)
  • American Association for the Advancement of Science
  • National Academy of Sciences
  • 2010-2014
  • 2005-2009
  • 1980-1984
  • 1975-1979  (11)
  • 1925-1929
  • 1975  (11)
Collection
Keywords
Publisher
  • Springer  (11)
  • American Association for the Advancement of Science
  • National Academy of Sciences
Years
  • 2010-2014
  • 2005-2009
  • 1980-1984
  • 1975-1979  (11)
  • 1925-1929
Year
  • 1
    Electronic Resource
    Electronic Resource
    Changes in the noradrenalin content and nuclear RNA synthesis in the rat brain during disturbance of emotional and conditioned-defensive behavior (1975)
    Springer
    Bulletin of experimental biology and medicine 80 (1975), S. 1035-1038 
    Details
    ISSN: 1573-8221
    Keywords: noradrenalin ; nuclear RNA synthesis ; rat brain ; mechanisms of memory ; emotional and conditioned-defensive behavior
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Exhaustion of the noradrenalin (NA) reserves in the rat brain caused by administration of reserpine or dopamine-β-oxidase blockers (disulfiram, diethyldithiocarbamate) is accompanied by a decrease in nuclear RNA synthesis and disturbances of emotional and conditioned-defensive behavior. During the accumulation of cerebral Na (following injection of iproniazid or imipramine) the rate of synthesis of nuclear RNA rises. Prevention of the exhausting effect of reserpine by preliminary injection of iproniazid also prevents the disturbance of nuclear RNA synthesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00799883
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of carbidine on content and deposition of adrenergic neurotransmitter in synaptic vesicles (1975)
    Springer
    Bulletin of experimental biology and medicine 80 (1975), S. 1208-1212 
    Details
    ISSN: 1573-8221
    Keywords: carbidine ; synaptic vesicles ; noradrenalin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The effect of the original Soviet psychotropic agent carbidine on the content and deposition of adrenergic mediator in the synaptic vesicles of sympathetic nerve fibers of the rat vas deferens was studied by electron-microscopic cytochemistry. The results showed that carbidine can reduce the reserves of monoamines deposited in synaptic vesicles but does not affect the uptake and accumulation of exogenous noradrenalin by synaptic vesicles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00833163
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of cocaine on the central action of noradrenalin (1975)
    Springer
    Bulletin of experimental biology and medicine 80 (1975), S. 1313-1315 
    Details
    ISSN: 1573-8221
    Keywords: cocaine ; noradrenalin ; impulse summation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The impulse-summation method was used to study the effect of cocaine on the central action of noradrenalin in experiments on rabbits. Cocaine was found to increase this action. Cocaine thus potentiates not only the peripheral effects of noradrenalin, as was already known, but also its central action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00835173
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  • 4
    Electronic Resource
    Electronic Resource
    Mechanism of action of nonachlazine on the blood supply and activity of the heart (1975)
    Springer
    Bulletin of experimental biology and medicine 80 (1975), S. 1319-1321 
    Details
    ISSN: 1573-8221
    Keywords: heart-blood supply and activity ; nonachlazine ; noradrenalin ; phosphorylase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Nonachlazine (10 mg/kg, intravenously) has a biphasic effect on cardiac activity. A short phase of weakening of cardiac activity is followed by a marked increase in the cardiac output and contractile function of the myocardium. The increase in the blood supply and activity of the heart coincides in time with the accumulation of noradrenalin in the myocardium and an increase in phosphorylasea. β-Adrenoblockers prevent the development of these effects. It is postulated that the effectiveness of nonachlazine in ischemic heart disease is connected with its ability to activate adrenergic mechanisms of glycogenolysis control, leading to switching of metabolism in the myocardium to the anaerobic pathway of energy liberation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00835175
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  • 5
    Electronic Resource
    Electronic Resource
    Activity of some enzymes of energy metabolism in the myocardium and liver after large doses of noradrenalin (1975)
    Springer
    Bulletin of experimental biology and medicine 80 (1975), S. 1425-1427 
    Details
    ISSN: 1573-8221
    Keywords: rat heart and liver ; noradrenalin ; glycolytic enzymes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Increases are found in the lactate concentration and lactate dehydrogenase activity in the myocardium and hexokinase and glucose-6-phosphate dehydrogenase activity in the myocardium and liver 24 h after intraperitoneal injection of large doses of noradrenalin, after exhaustion of its reserves in the myocardial and hepatic tissues of rats. Activity of glucokinase, which phosphorylates glucose when present in high concentrations in the medium, is reduced. Changes in enzyme activity thus observed are similar to those developing in degeneration of denervated tissues, with a sharply reduced catecholamine content, and they confirm the important role of the sympathetic nervous system and its mediators in the mechanism for controlling enzymic processes of energy metabolism in the myocardium and liver.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00842627
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  • 6
    Electronic Resource
    Electronic Resource
    Mechanism of noradrenalin liberation from the rat brain under the influence of nicotine (1975)
    Springer
    Bulletin of experimental biology and medicine 80 (1975), S. 900-902 
    Details
    ISSN: 1573-8221
    Keywords: ATPase ; noradrenalin ; nicotine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Definite relationships were found between the noradrenalin concentration and Mg++-ATPase activity in the rat brain during the action of nicotine. It is suggested that Mg++-ATPase regulates the storage of noradrenalin in the tissue depots.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00789265
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  • 7
    Electronic Resource
    Electronic Resource
    Intracellular mechanism of action of imipramine and diazepam (1975)
    Springer
    Bulletin of experimental biology and medicine 80 (1975), S. 1205-1207 
    Details
    ISSN: 1573-8221
    Keywords: noradrenalin ; hypothalamus ; imipramine ; diazepam
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Subcellular fractionation of the tissue of the hypothalamus was carried out by differential centrifugation in experiments on rats. The effect of the antidepressant imipramine and the tranquilizer diazepam on the noradrenalin content was determined in the isolated fractions. The results showed that imipramine lowers the noradrenalin content in the synaptosomes but diazepam has no such effect. The adrenergic component thus plays an important role in the mechanism of action of the first of these substances, but not in the action of the second.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00833162
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of noradrenalin on electrical and contractile properties of smooth-muscle cells of the pulmonary artery (1975)
    Springer
    Bulletin of experimental biology and medicine 80 (1975), S. 1147-1149 
    Details
    ISSN: 1573-8221
    Keywords: smooth muscle of pulmonary artery ; volt-ampere characteristic curves ; muscle contraction ; noradrenalin ; phentolamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Muscle cells of the pulmonary artery have no spontaneous activity. Electrical stimulation of these cells leads to the formation of electronic potentials unaccompanied by any change in isometric contraction of a strip of the artery. Noradrenalin, in a concentration of 10−8 g/ml, causes depolarization of the muscle cell membrane by 5–7 mV and a marked increase in contraction of the muscle strip. Under these conditions, catelectronotonic depolarization was accompanied by contraction of the strip, but anelectrotonic hyperpolarization by its relaxation. Phentolamine, and α-adrenoblocker, prevents the noradrenalin effect, indicating a role of α-adrenoblockers in the mechanism of the excitatory action of noradrenalin on the smooth-muscle cells of the pulmonary artery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00833141
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  • 9
    Electronic Resource
    Electronic Resource
    Effect of prostaglandin E1 and noradrenalin on cerebrovascular tone and arterial blood pressure (1975)
    Springer
    Bulletin of experimental biology and medicine 79 (1975), S. 549-551 
    Details
    ISSN: 1573-8221
    Keywords: Prostaglandins ; noradrenalin ; cerebral hypertension ; systematic hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Prostaglandin E1 (PGE1), in solution with ethanol, when injected into the carotid artery, increases the tone of the cerebral blood vessels and the arterial blood pressure, whereas PGE1 without ethanol gives the opposite effect. When PG biosynthesis is blocked by indomethacin, the pressor effect of noradrenalin on the cerebral vessels was considerably increased. It is postulated that PGE1 is an important component of the system participating in the genesis of cerebral hypertension and determining the character of its course.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00800499
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  • 10
    Electronic Resource
    Electronic Resource
    Action ofα-methyl-p-tryrosine on development of neurogenic degeneration of the gastric wall and its noradrenalin content (1975)
    Springer
    Bulletin of experimental biology and medicine 79 (1975), S. 628-629 
    Details
    ISSN: 1573-8221
    Keywords: noradrenalin ; neurogenic degeneration of the stomach
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The effect of α-methyl-p-tyrosine (50 mg/kg) was studied on the development of hemorrhagic erosions in the stomach wall and the noradrenalin content in it during electrical stimulation of immobilized rats. The α-methyl-p-tyrosine significantly increased the number of hemorrhagic erosions of the stomach wall and potentiated the fall in its noradrenalin level arising as a result of electrical stimulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00786413
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  • 11
    Electronic Resource
    Electronic Resource
    Role of noradrenergic terminals of the rat brain in passive-avoidance conditioning (1975)
    Springer
    Bulletin of experimental biology and medicine 79 (1975), S. 604-605 
    Details
    ISSN: 1573-8221
    Keywords: conditioned passive-avoidance reflex ; noradrenalin ; noradrenergic terminals ; brain nuclei
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Changes in the noradrenalin concentration in noradrenergic terminals were studied by a fluorescence-histochemical method in pars ventralis nuclei interstitialis striae terminalis, nucleus septi lateralis, and nucleus preopticus medialis in rats during passive-avoidance conditioning. In preliminarily trained animals the simple reproduction of the conditioned-reflex response (without electrical stimulation of the skin) led to a decrease in the noradrenalin concentration in all structures studied. The results indicate a role in the noradrenergic system of the brain in the reproduction of the passive-avoidance conditioned reflex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00786405
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