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  • Articles  (7,296)
  • Springer  (6,166)
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  • 1975  (7,296)
  • Medicine  (7,061)
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  • Articles  (7,296)
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  • 1975-1979  (7,296)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 14 (1975), S. 125-132 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Notes: Summary The research work for the culture of yeasts on hydrocarbon substrates has started in 1959 at the research laboratory of Lavera in France, underChampagnat as leader. Its result is the construction and exploitation of 2 industrial plants in France and England, and a new big one is being built in Italy. The paper describes the various hydrocarbon substrates in use or proposed, and the two BP processes. It gives the main characteristics of the yeasts produced. It emphasizes the methods used for the evaluation of the yeasts both toxicologically and nutritionally by independent organizations of international level. A number of tables are given upon the nutritional performances of the yeasts on farm animals. Authorizations of use have been obtained from the hygiene authorities of the main European countries. The use for human consumption is now being considered.
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  • 2
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    European journal of nutrition 14 (1975), S. 161-161 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
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  • 3
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    European journal of nutrition 14 (1975), S. 162-162 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
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  • 4
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary If we admit the hyperammoniemy as one of the factors of portal systemic encephalopathy, then the decrease in protidic contribution seems justified. But the prescription of a long-term lav-protein diet in cirrhosis, with portal hypertension, with spontaneous or surgical porto case shunts is unsatisfactory; because it is necessary to give the maximum amount of protein compatible with a normal psychic state, in order to let the hepatic cells regenerate and to restrain nitrogenous catabolism. The authors relate their experiences with another diet, with an adequate (80 g) and balanced (15%) protidic untake, essentially provided by milk products (with lav-sodium content if necessary). This diet not only induces an encephalopathy aggravation, but on the contrary helps to cure it. These products are well tolerated because of the bacteriological and biochemical composition of milk and cheese, which changes the equilibrium of the intestinal flora in favour of a flora without ammonium. The results of this well tolerated diet offer particular interest in the sequels of surgical porto cave anastomosis, but depend obviously on the degree of hepatic cellular insufficiency which condition the liver's inhibition of protein intake.
    Abstract: Zusammenfassung Wenn man annimmt, daß die Hyperammoniämie einer der Faktoren der portokavalen Enzephalopathie ist, scheint die Reduzierung der Proteinzufuhr gerechtfertigt zu sein. Aber die Verordnung einer langfristigen proteinarmen Diät bei Zirrhosen mit portaler Hypertonie, mit spontanen portokavalen oder chirurgischen Shunts ist unbefriedigend. Es ist in der Tat notwendig, ein Maximum von Proteinen, die mit einem normalen neuropsychischen Zustand kompatibel sind, zuzuführen, um die Regeneration der Leberzelle zu ermöglichen und um den Stickstoffkatabolismus, der selbst ein Ammoniakerzeuger ist, zu bremsen. Die Autoren berichten über ihre Erfahrungen der „Milch- und-Käse“-Diät, die eine genügende Proteinration (80 g) sichert und die ausgeglichen ist (12 % der Kalorien). Diese Proteine werden ausschließlich durch Milchprodukte, die, wenn es notwendig ist, salzarm sind, geliefert. Diese lösen keine Verschlechterung der Enzephalopathie aus, sondern bessern diese im Gegenteil. Diese Verträglichkeit wurde durch die bakteriologische und biochemische Zusammensetzung der Milch und des Käses, die das Gleichgewicht der Darmflora zugunsten einer nicht Ammoniak erzeugenden Flora verändern würden, bedingt. Die Ergebnisse dieser gut angenommenen Diät sind besonders bei den Folgen der chirurgischen portokavalen Anastomosen interessant, hängen aber natürlich von dem Grad der Insuffizienz der Leberzellen, die die Verwertung der zugeführten Proteine durch die Leber bedingt, ab.
    Notes: Résumé Si l'on admet que l'hyperammoniémie est un des facteurs de l'encéphalopathie porto-cave, la réduction des apports protéiques paraît justifiée. Mais la prescription au long cours d'un régime hypoprotidique dans les cirrhoses avec hypertension portale, avec shunts porto-caves spontanés ou chirurgicaux, n'est pas satisfaisante. En effet, il est nécessaire d'apporter le maximum de protides, compatibles avec un état neuropsychique normal, pour permettre la régénération de l'hépatocyte et pour freiner le catabolisme azoté, lui même générateur d'ammoniaque. Les auteurs rapportent leur expérience du régime « lait et fromages » qui assure une ration protidique suffisante (80 g) et équilibrée (12% des calories), fournie essentiellement par les produits laitiers, pauvre en sodium si nécessaire et qui n'entraîne pas l'aggravation de l'encéphalopathie bien au contraire l'améliore. Cette tolérance serait due à la composition bactériologique et biochimique du lait et des fromages qui modifierait l'équilibre de la flore intestinale au profit d'une flore non ammonio-formatrice. Les résultats de ce régime bien accepté sont particulièrement intéressants dans les suites d'anastomoses porto-caves chirurgicales mais dépendent évidemment du degré de l'insuffisance cellulaire hépatique qui conditionne l'utilisation par le foie des apports protidiques.
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  • 5
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    European journal of nutrition 14 (1975), S. 145-160 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Zusammenfassung Die letzten Jahre haben auf dem Gebiet der Aufrechterhaltung der Homöostase im Schock, nach Traumen, nach Streß, nach Blutungen, nach Ernährungs- und Stoffwechselstörungen und nach Infekten entscheidende Erkenntnisse gebracht. Diese gewinnen bei einer steigenden Zahl von Verletzten und Kranken lebensrettende Bedeutung durch Erweiterung der Therapiemöglichkeiten, wie sie bisher nicht denkbar waren. Entscheidend beigetragen hat zu dieser Entwicklung die kollegiale Zusammenarbeit von Grundlagenforschern (vor allem physiologischen Chemikern) einerseits und Klinikern andererseits (vor allem Anästhesiologen, Chirurgen, Internisten, Reanimatologen usw.), vereinigt in gemeinsamen Bemühungen um Fortschritte auf dem Gebiet der Intensivtherapie. Die vorliegende Arbeit möchte einen speziellen nicht nur theoretisch, sondern auch praktisch wichtigen Beitrag leisten zu dieser Entwicklung: Die Zurückdrängung der Bluttransfusion (gefährlich wegen der schlechten Haltbarkeit, häufigen Unverträglichkeit und der Gefahr der Übertragung von Infektionskrankheiten wie Hepatitis, Syphilis usw.) durch die heute vorhandenen verbesserten Aminosäurengemische. Diese sind gut verträglich, lange lagerfähig und bei vielen neuen Indikationen wirkungsvoller als das bisher hierfür verwendete Blut und seine Derivate. Die neuen Aminosäurengemische sind deshalb berufen, besonders in der Katastrophenmedizin und in der postoperativen Behandlung eine bedeutende Rolle zu spielen und eine bisher oft bedrückende Lücke in der Versorgung der uns anvertrauten Kranken zu schließen. Einen Überblick über diese neuen Möglichkeiten zu geben, ist das Ziel dieser Arbeit.
    Notes: Summary In recent years, there have been conclusive findings in the field of maintaining homeostasis following trauma, bleeding, nutritional and metabolic disturbances and infections. These findings can help save the lives of an increasing number of injured and sick by enlarging the therapeutic possibilities which have previously been unimaginable. This development has been made possible by the good cooperation of both basic research and clinical staff whose common aim was to achieve advances in this field of intensive care. The aim of the present study is to make a relevant theoretical and practical contribution to the widening possibilities and necessities in this field.
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  • 6
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    European journal of nutrition 14 (1975), S. 163-174 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
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  • 7
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    European journal of nutrition 14 (1975), S. 133-144 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary The purpose of the present article is to give a survey of present knowledge of the ecological relationships between the various bacterial populations composing the microflora of the digestive tract of the host animal. Analysis of the relationships can be made with the aid of recent techniques: utilization of axenic animals (germ-free) and of gnotoxenic animals inoculated with known bacterial populations; perfecting of bacteriological techniques for the quantitative differential analysis of the various bacterial populations in the digestive tract, especially in the case of strictly anaerobic species. Some characteristics of the equilibrium between the various bacterial populations in the different segments of the gastro-intestinal tract have been described as well as some of the mechanisms which regulate this equilibrium. These mechanisms either imply interactions between bacteria or the action of the host animal and the environment on the microflora. Lastly, various examples concerning the action of the microflora in the digestive tract on the nutritional physiology of the host animal are given; action on the anatomy of the digestive tract and on the metabolism of carbohydrates, proteins, lipids and vitamins.
    Abstract: Zusammenfassung Der vorliegende Artikel hat zum Ziel, unsere heutigen Kenntnisse über die ökologischen Beziehungen zwischen den verschiedenen Bakterienpopulationen, die die Magen-Darm-Flora bilden, und dem Wirtstier zusammenzufassen. An Hand neuer Techniken konnte die Untersuchung dieser Beziehungen vorgenommen werden: Verwendung „axenischer“ (keimfreier) Tiere und „gnotoxenischer“, d. h. mit bekannten Bakterienpopulationen beimpfter Tiere; Verbesserung der bakteriologischen Techniken für die quantitative Differenzanalyse der verschiedenen Bakterienpopulationen im Verdauungskanal, insbesondere der streng anaeroben Arten. Einige Eigenschaften des Gleichgewichtes zwischen den verschiedenen Bakterienpopulationen in den verschiedenen Abschnitten des Magen-Darm-Kanals wurden beschrieben sowie auch einige Mechanismen, die dieses Gleichgewicht steuern. Diese Mechanismen setzen entweder Wechselwirkungen zwischen den Bakterien oder eine Auswirkung des Wirtstieres und der Umwelt auf die Bakterienflora voraus. Schließlich werden einige Beispiele der Wirkung der Magen-Darm-Flora auf die Ernährungsphysiologie des Wirtes dargelegt: Wirkung auf die Anatomie des Verdauungskanals und auf den Stoffwechsel der Kohlenhydrate, des Stickstoffes, der Fette und der Vitamine.
    Notes: Résumé Le but de cet article est de résumer nos connaissances actuelles concernant les relations écologiques entre les diverses populations microbiennes qui constituent la microflore du tube digestif et l'animal-hôte. Des techniques nouvelles ont permis d'entreprendre l'analyse de ces relations: utilisation d'animaux «axéniques», dépourvus de bactéries et «gnotoxéniques» ensemencés avec des populations bactériennes connues; perfectionnements des techniques bactériologiques pour l'analyse différentielle quantitative des diverses populations bactériennes du tube digestif, en particulier dans le cas des espèces anaérobies strictes. Quelques caractéristiques de l'équilibre entre les différentes populations bactériennes dans les différentes parties du tractus gastro-intestinal ont été décrites ainsi que quelques uns des mécanismes qui régulent cet équilibre. Ces mécanismes impliquent soit des interactions entre les bactéries, soit l'action de l'animal hôte et de l'environnement sur la microflore. Enfin divers exemples de l'action de la microflore du tube digestif sur la physiologie nutritionnelle de l'hôte ont été présentés: action sur l'anatomie du tube digestif et sur les métabolismes glucidiques, azoté, lipidique et vitaminique.
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  • 8
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    European journal of nutrition 14 (1975), S. 175-183 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Zusammenfassung Die Verfütterung von Fritierfetten an Ratten ergab in allen untersuchten Parametern keine Unterschiede gegenüber den Verhältnissen bei den Kontrolltieren, welche die entsprechenden nichterhitzten Fette (partiell hydriertes Erdnußöl, Sojaöl) in derselben Menge und über den gleichen Zeitraum erhalten hatten. Untersucht wurden: Konzentration der Plasmalipide einschließlich des Gesamtcholesteringehaltes, Elektrophorese der Plasmalipoproteine, Fettsäurezusammensetzung der Plasmalipide und des Depotfetts sowie Menge und Zusammensetzung des Unverseifbaren einschließlich des Gehaltes an den polycyclischen Kohlenwasserstoffen. In In-vitro-Versuchen untersuchten wir die Wirkung der Pankreaslipase auf nichterhitzte und erhitzte Fette.
    Notes: Summary In feeding experiments no differences could be observed when used frying fats were fed to rats in the same amount and over the same period if compared with the unheated fats (partially hardened groundnut oil, soyabean oil). In details we investigated: concentration of plasma lipids including content of total cholesterol, electrophoresis of plasma lipoproteins, fatty acid composition of plasma lipids and of adipose tissue. Amount and composition of the unsaponifiable matter in heated and unheated fats as well as the content of polycyclic aromatic hydrocarbons were determined. In in-vitro experiments we investigated the effect of pancreas lipase on these fats.
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  • 9
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    European journal of nutrition 14 (1975), S. 218-224 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Zusammenfassung Das Ziel dieser Unterredung war, den Einfluß verschiedener Volumen von vergrößernden Stoffen der Diät auf die Gallensteinbildung beim Hamster zu studieren. Dabei wurden die Substanzen Pectin, Lignin und Psylliumhydrokolloid benützt. Die zwei letzteren schützten die Hamster gegen die Bildung von Cholesteringallensteinen. Lignin bewirkte eine Verminderung der Konzentration von Deoxycholsäure und eine Steigerung in der Chol-/Chenodeoxycholsäure-Konzentration. Ähnliche Veränderungen findet man bei Zufuhr von Cholestyramine, was für eine Bindung von Gallensäure bei Lignin sprechen könnte. Psylliumhydrokolloid bewirkte eine ähnliche Steigerung der Chol-/Chenodeoxycholsäure-Konzentration, aber auch eine Steigerung der Deoxycholsäurekonzentration. Der letztere Befund von Psylliumhydrokolloid ist nicht mit einer Bindung von Gallensäure zu vereinbaren. Bei Zugabe von Alkohol zum Trinkwasser wurden pigmentreiche Steine gebildet. Unter diesen Bedingungen wurde die Bildung von solchen Steinen bei keiner dieser angewandten Substanzen vermieden.
    Notes: Summary This study aimed at investigating the effect of different sources of dietary fibre on gallstone formation in hamsters. The substances studied were pectin, lignin and psyllium hydrocolloid. The two latter compounds protected hamsters against cholesterol gallstone formation. Lignin resulted in a decrease of the deoxycholic acid concentration and in a rise of the cholic/chenodeoxycholic acid ratio. These changes which are similar to those observed with cholestyramine suggest that lignin acts as a bile acid sequestrant. Psyllium hydrocolloid effected a similar shift of the cholic/chenodeoxycholic acid ratio but it also resulted in a rise of the deoxycholic concentration. This latter finding is not compatible with a bile acid sequestering role of this compound. The addition of alcohol to the drinking-water resulted in the formation of stones rich in pigment. Under these conditions the tendency to form such stones was not checked by either of the investigated substances.
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  • 10
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    European journal of nutrition 14 (1975), S. 225-229 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Notes: Zusammenfassung Die Lupine Lupinus mutabilis gehört mit zu den ersten landwirtschaftlichen Nutzpflanzen der Andenkulturen Südamerikas. Noch heute spielt die Lupine eine Rolle bei der Proteinversorgung der Andenbewohner, allerdings nimmt der Anbau der Pflanze immer mehr ab. Auf Grund des hohen Ölund Proteingehaltes des Lupinensamens und der Anspruchslosigkeit der Pflanze kann ihr in Zukunft wieder mehr Bedeutung beigemessen werden. Hierfür sind jedoch noch folgende Untersuchungen notwendig: 1. Züchterische Bearbeitung 2. Technologische Studien zur Öl- und Ölkuchenproduktion und deren Verwertung 3. Vorklinische und klinische Untersuchungen 4. Akzeptabilitätstests
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  • 11
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    European journal of nutrition 14 (1975), S. 184-217 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary Metabolic effects of glucose, fructose, sorbitol, xylitol and their combinations during intravenous application in men were investigated. The totale and metabolic clearance, the renal and metabolic elimination, the half-time and the turnover rate were measured. For all sugars intravenous long-term infusions from six to twelve hours were performed. Up to a dosage of 0.75 g/kg/h for glucose 0.5 g/kg/h for sorbitol and 0.25 g/kg/h for fructose and xylitol a steady state of substrates and metabolites has been found. If these dosage-limits are exceeded during glucose application a hyperglucosemia, after sorbitol a continous rise in sorbitol blood level, during fructose a rise in lactate and during xylitol infusion clinical side effects occurred. It could be shown that during simultaneous application of glucose, fructose and xylitol the utilization of glucose rises whereas the utilization of fructose and xylitol remain on such levels as if these sugar were infused alone.
    Notes: Zusammenfassung Für die Kohlenhydrate Glukose und Fruktose sowie die Polyalkohole Sorbit und Xylit und deren Mischungen wurden die totale Clearance, die metabolische Clearence, die totale, metabolische und renale Eliminationskonstante, die biologische Halbwertzeit und die mittlere Umsatzzeit berechnet. Voraussetzung hierzu waren intravenöse Dauerinfusionen mit den jeweiligen Kohlenhydraten über Zeiträume von mindestens sechs Stunden. Während dieser Zeit mußte sich ein Fließgleichgewicht der Substratspiegel im Blut und der Folgemetaboliten sowie eine konstante Kohlenhydratelimination ausgebildet haben. Diese Zufuhrraten betragen über sechs Stunden für Glukose 0,75 g/kg, für Sorbit 0,5 g/kg, für Fruktose 0,25 g/kg und für Xylit ebenfalls 0,25 g/kg. Bei Überschreiten dieser Dosierungsgrenzen kommt es nach Glukosezufuhr zur Hyperglykämie, nach Sorbit zum kontinuierlichen Anstieg des Sorbitspiegels, nach Fruktose zur kontinuierlichen Laktaterhöhung, nach Xylit zu klinischen Nebenwirkungen, welche auf eine Elektrolytverschiebung zurückgeführt werden könnten. Es gelang durch Messung der Substratkonzentration und der totalen Clearance der Nachweis, daß während gleichzeitiger Applikation von Glukose, Fruktose und Xylit die Verwertung der Glukose ansteigt, die von Fruktose und Xylit aber ebenso groß bleibt, als wenn diese Substrate alleine infundiert worden wären.
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  • 12
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Notes: Zusammenfassung In einem Wachstumstest an Ratten wurde die Proteinqualität von Lupinus mutabilis im Vergleich zu Lupinus albus, Lupinus luteus und Soja getestet. Der niedrige PER-Wert von 37,1%, bezogen auf Kasein (=100%), liegt in dem starken Mangel an Methionin begründet und läßt sich durch Zumischen von 0,6% DL-Methionin oder eines an schwefelhaltigen Aminosäuren reichen Samens, wie Chenopodium quinoa, auf 133,7% oder 97,0 bzw. 108,4%, bezogen auf das Testprotein, steigern. Wachstumshemmende Proteine, wie Trypsinhemmer, die in vielen Leguminosen vorhanden sind, scheinen nicht oder nur im geringen Maße im Samen von Lupinus mutabilis vorhanden zu sein.
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  • 13
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    European journal of nutrition 14 (1975), S. 251-251 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
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  • 14
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    European journal of nutrition 14 (1975), S. 235-243 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary The influence of oral milk foods on the fatty acid pattern of the total serumlipids was examined on 58 healthy infants and small children. It is known that the newborn's fatty acid pattern is different to that of the adult's. These differences pertain chiefly to the essential linoleic acid and arachidonic acid as well as to the other fatty acids. The time of adaptation to the adult's fatty acid pattern was to be ascertained. The result was that a speedy approximation depended on the food used and it's particular fatty acid pattern.
    Notes: Zusammenfassung Bei 58 gesunden Säuglingen und Kleinkindern wurde der Einfluß oraler Säuglingsmilchnahrungen auf das Fettsäuremuster der Serumgesamtlipide untersucht. Bekanntlich unterscheidet sich das Fettsäuremuster des Neugeborenen von dem des Erwachsenen. Diese Unterschiede betreffen neben anderen Fettsäuren vornehmlich die essentielle Linolsäure und Arachidonsäure. Es sollte der Zeitpunkt einer Adaptation an das Fettsäuremuster des Erwachsenen ermittelt werden. Dabei stellte sich heraus, daß eine rasche Annäherung von der verwendeten Nahrung und deren Fettsäuremuster abhängig ist.
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  • 15
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    European journal of nutrition 14 (1975), S. 244-250 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary The law protein nutrition of the nursing rat inhibits the growth of the new born rats. A percentage reduction of the dry substance by decrease of N2-free substances takes place. In relation to g dry substance the body protein content, collagen also, rises. Absolutely, these parts rest unaltered, just so the relation of the parenchymatous protein to collagen. The often support of view that starving provokes a collagen formation of the body, that means an exceed of the framework, can not be confirmed. Though in this paper we can give an explanation for the occurrence of this conclusion. Long interruptions of lactation periods remarkably have no effect on the growth and on the main compartments of the body of new born rats. Only tryptophane is reduced in favour of the serine-fraction in the body of those animals. We discuss this finding as a change of the metabolisme of tryptophane depending of stress.
    Notes: Zusammenfassung Die eiweißarme Ernährung der stillenden Rattenmutter hemmt das Wachstum des neugeborenen Wurfes. Dabei tritt eine prozentuale Reduktion der Trockensubstanz durch Verminderung von N2-freien Stoffen auf, so daß sowohl parenchymatöses als auch kollagenes Eiweiß im Trockenanteil des Körpers dieser Tiere gegenüber den Kontrollen überwiegt. Absolut gesehen bleiben aber diese Fraktionen unverändert bestehen; auch ist die Relation Parenchymeiweiß zu Kollagen — gemessen am Aminosäurenspektrum — konstant. Die oft vertretene Auffassung, daß das Hungern eine „Kollagenisierung“ des Körpers, also das Überwiegen des Gerüstanteiles, bedingt, wird nicht bestätigt, obgleich hier eine Erklärung für das Zustandekommen dieser Schlußfolgerung gegeben wird. Lange Unterbrechungen der Stillperioden rufen bemerkenswerterweise keine Auswirkungen auf das Wachstum und auf die Körperhauptkompartiments der neugeborenen Ratten hervor. Lediglich vermindert sich der Tryptophan- zugunsten des Serinanteiles im Körper dieser Tiere. Dieser Befund wird als belastungsbedingte Änderung im Tryptophanstoffwechsel diskutiert.
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  • 16
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    European journal of nutrition 14 (1975), S. 268-271 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary 1. Washed human erythrocytes metabolize 1,14μMol xylitol in 120 min under the following experimental conditions: pH 7.4 and 37° C. 2. The levels of 2,3-diphosphoglycerate and ATP decrease during the incubation with xylitol. This decrease is not a specific effect of xylitol, but depends on the amount of C-atoms taken up. This could be shown in control experiments with fructose and glucose as substrates given separated or in combination with xylitol. The highest uptake of C-atoms has been observed with glucose plus xylitol as substrate. 3. 99% of the metabolized xylitol was recovered in the products lactate, Co2 and D-xylulose. 4. There was no measurable oxalate production from xylitol.
    Notes: Zusammenfassung 1. Gewaschene, menschliche Erythrozyten verstoffwechseln unter experimentellen Bedingungen (pH 7,4, 37° C) 1,14μMol Xylit in 120 min. 2. Der 2,3-DPG- und ATP-Spiegel fällt während der Inkubation mit Xylit ab. Dieser Abfall ist keine spezifische Wirkung des Xylits, sondern hängt von der Menge der aufgenommenen C-Atome ab. Dies zeigten Vergleichsuntersuchungen mit den Substraten Fruktose und Glukose allein und in Kombination mit Xylit. Die höchste Aufnahme an C-Atomen wurde mit Glukose+Xylit als Substrat erreicht. 3. Der verstoffwechselte Xylit wurde zu 99% in den Produkten Laktat, CO2 und D-Xylulose wiedergefunden. 4. Eine Oxalatbildung aus Xylit konnte nicht nachgewiesen werden.
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    Cellular and molecular life sciences 31 (1975), S. 1126-1128 
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    Notes: Summary The kinetic order of addition of Mg2+ andl-malate to malic enzyme has been determined. Mg2+ is the first to bind, and probably acts as a link between the substrate and the active site.
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    Cellular and molecular life sciences 31 (1975), S. 1132-1134 
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    Notes: Summary The concentration of certain of the very low density human serum lipoprotein apoproteins were found to increase following a meal, while the concentrations of the majority of the apoproteins were found to be unaffected.
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    Cellular and molecular life sciences 31 (1975), S. 1137-1137 
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    Notes: Summary Human leukocytes and lymphocytes have shown to be equipped with 5-phosphoribosyl-1-pyrophosphate amidotransrease, the enzyme which catalyzes the synthesis of the first intermediate of the purine pathway, thus providing evidence that these cells have the capacity for de novo purine biosynthesis.
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    Cellular and molecular life sciences 31 (1975), S. 1141-1143 
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    Notes: Summary 4 of the 5 subspecies ofGeomys pinetis were karyotyped. All specimens examined had a diploid number of 42 and a fundamental number of 80. This karyotype was compared with the described karyotypes of other species ofGeomys and was considered to be derived from an ancestoral form having a karyotype of about 70 acrocentric elements.
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    Cellular and molecular life sciences 31 (1975), S. 1145-1145 
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    Notes: Summary A connection is made plausible between the efficiency of milk-cows and the generation age of the father bulls.
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    Cellular and molecular life sciences 31 (1975), S. 1151-1152 
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    Notes: Summary Hybridization assays of rat liver mitochondrial and cytoplasmic rRNAs with in vitro labelled mitochondrial and nuclear DNA were performed in liquid medium. Sensitivity towards S1 enzyme and Tms of the RNA-DNA hybrids were studied. Our results are in favour of a distinct genetic origin of the two types of cellular rRNAs.
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    Cellular and molecular life sciences 31 (1975), S. 1155-1157 
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    Notes: Summary The infection of MLO in a soil microfungus (Humicola sp.) originates different types of non-lethal parasitism. Differences have been found in the U.V. sensitivity and nuclear characters according to the type of MLO-microfungus interrelationship.
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    Cellular and molecular life sciences 31 (1975), S. 1163-1164 
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    Notes: Resumen Alcohol coniferílico fue identificado de los exudados producidos por callos deCastanea sativa Mill. cultivados in vitro, originados de cotiledón.
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    Cellular and molecular life sciences 31 (1975), S. 1165-1166 
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    Notes: Summary Polycationic modified derivatives of polyglutamic acid are at least as good enhancers of poly I:C induced viral resistance in various cell cultures as are DEAE-dextran or poly-l-lysine.
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    Cellular and molecular life sciences 31 (1975), S. 1167-1170 
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    Notes: Zusammenfassung Im intakten Penisretraktormuskel-Nerv-Gehirn-Präparat vonHelix pomatia L. treten sowohl tonische als auch phasische Muselkontraktionen auf. Die phasische Kontraktion scheint von peripheren Neuronen gesteuert zu werden, während für die Steuerung der tonischen Kontraktion zentrale Strukturen eine Rolle spielen.
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    Cellular and molecular life sciences 31 (1975), S. 1173-1174 
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    Notes: Summary Jaundiced plasma and plasma from hyperlipidaemic patients was perfused into an isolated artery or kidney preparation. The responses of the artery to doses of noradrenaline when Krebs solution was perfused were compared to the responses when the plasmas were perfused. It was found that both jaundiced and hyperlipidaemic plasmas potentiated the effects of noradrenaline on the isolated arteries and kidneys.
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    Cellular and molecular life sciences 31 (1975), S. 1178-1179 
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    Notes: Summary The discharge frequency of miniature endplate potentials was increased by the UV-light application. This phenomenon can be attributed to the effect on the presynaptic terminal.
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    Cellular and molecular life sciences 31 (1975), S. 1199-1200 
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    Notes: Summary PGE1 administration to isolated strips from pregnant and lactating rabbit mammary gland resulted in different effects on oxytocin-induced contractions. In strips from pregnant animals, oxytocin action was enhanced; in those from lactating animals, it was reduced and threshold doses for oxytocin were markedly higher.
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    Cellular and molecular life sciences 31 (1975), S. 1121-1122 
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    Notes: Summary Aside from cholesterol, cholesterol esters and lyso-lecithin, the de novo lipid synthesic mechanisms which operate in cells grown in the presence of β-aminopropionitrile are largely depressed and suggest that there may be in operation specific metabolic control mechanisms for regulation of cellular lipid composition.
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    Notes: Résumé Le S 3608 [1-(coumaran-5-yl méthyl)-4-(2-thiazolyl) pipérazine] produit une important activation des récepteurs centraux de dopamine chez le rat. Les résultats permettent de formuler l'hypothèse d'un mécanisme d'action direct aux doses faibles.
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    Cellular and molecular life sciences 31 (1975), S. 1117-1118 
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    Notes: Riassunto Si descrive il ritrovamento nella spugnaD. pallescens di un croman-sesquiterpenoide,ent-chromazonarolo (2), enantiomero del cromanolo dello zonarolo, sesquiterpene idrochinonico isolato dall'algaDictyopteris undulata (zonarioides).
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    Cellular and molecular life sciences 31 (1975), S. 1205-1207 
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    Notes: Summary The doses of reserpine, which are generally used to deplete amines from the nervous tissue caused marked ultrastructural changes in the neural lobes of reserpine treated rats. The findings suggested depletion of neurosecretory granules, increased lysosomal activity and changes in the pituicytes.
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    Cellular and molecular life sciences 31 (1975), S. 1207-1208 
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    Notes: Zusammenfassung Bei elektronenmikroskopischen Untersuchungen an Muskelbiopsien von Kranken mit progressiver Sklerodermie konnten in einem Fall ungewöhnlich viele, grösstenteils kugelige Mitochondrien mit einem Durchmesser von 0,03–0,05 μm subsarkolemmal beobachtet werden. Zwischen diesen befanden sich zahlreiche stäbchenförmige Mitochodnrien mit einer Länge von 1–3 μm und einer Dicke von 0,15–0,75 μm, deren Enden etwas kappenartig erweitert sind und eine normale Matrix mit einzelnen Cristae aufweisen, während die übrige Matrix homogen erscheint.
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    Cellular and molecular life sciences 31 (1975), S. 1213-1215 
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    Notes: Summary The γ-ray irradiation causes mortality, retardation in development and growth rate, haemorrhage, axial defects and unilateral microphthalmia. Histological examination of microphthalmic embryos revealed a partial division of the left optic cup and a ‘double lens’.
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    Cellular and molecular life sciences 31 (1975), S. 1218-1221 
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    Notes: Summary An antagonism between prolactin and thyroxine, similar to that found in amphibian tissues at at metamorphosis, has been recently shown to occur at the level of the rat mammary epithelium. This phenomenon may be implicated in the pathogenesis of human breast cancer. This experiment demonstrates that two analogues of thyroid hormone, triiodothyropropionic acid and triiodothyroacetic acid, which are relatively very weak in their calorigenic action, are as potent as thyroxine and triiodothyronine in inhibiting the prolactin-mediated mammary growth in thyroidectomized rats. The possible implication of this finding in the treatment of mammary cancer is discussed.
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    Cellular and molecular life sciences 31 (1975), S. 1229-1230 
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    Notes: Summary Antisera against purified monoclonal IgM from patients with Waldenström's macroglobulinemia were raised in guinea-pigs. Absorption with normal human serum and heterologous macroglobulinemic serum resulted in an antiserum to a subgroup present in 5 of 54 sera.
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    Cellular and molecular life sciences 31 (1975), S. 1233-1234 
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    Notes: Summary The production of antibodies against amanitins is described. By means of these antibodies, a radioimmunoassay was developed which allows detection of as little as 0.5 ng of amanitins in 1 ml of serum. By this method, the clearance of α-amanitin from the blood of poisoned mice was measured.
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    Cellular and molecular life sciences 31 (1975), S. 1221-1223 
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    Notes: Summary The administration of ox-spleen homogenate, whether in rats made polycythemic by blood transfusion or in mice polycythemic by hypoxia, elicited a significant stimulatory effect on the rate of erythropoiesis. This activity remained unchanged even if the spleen, before being homogenized, was exhaustively washed with isotonic buffer pH 7.4 up to the total blood elimination.
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    Cellular and molecular life sciences 31 (1975), S. 1246-1247 
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    Notes: Summary A method for the titration of anti-Con A sera is described. The test is based on the fact that agglutination of Con A-coated human erythrocytes can be prevented by agitation; subsequent addition of Con A-specific antisera and IgG to Con A-coated cells leads to immediate clumping.
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    Cellular and molecular life sciences 31 (1975), S. 1258-1260 
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    Notes: Summary The highest lactate dehydrogenase (LDH) activity was found in thalamus, statistically significantly less in cerebral and cerebellar cortex and the lowest in pons. LDH1 and LDH4+5 represented 58% and 23% of the total activity in cerebral cortex, 54% and 20% in thalamus, 42% and 4% in cerebellar cortex and 55% and 7% in pons, respectively.
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    Cellular and molecular life sciences 31 (1975), S. 1261-1262 
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    Notes: Summary The phospholipid level in the human parasitic nematodeAscaris lumbricoides is decreased by piperazine, by partially stimulating catabolic enzymes such as phospholipase C and partially inhibiting anabolic enzymes such as choline kinase.
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    Cellular and molecular life sciences 31 (1975), S. 1265-1266 
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    Notes: Summary Tryptophan (4–10 mM) reduces the stimulating effect of insulin on glucose uptake, CO2 output and lactate production by adipose tissue. Similar but lesser effects were also obtained with high concentrations of other amino acids.
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    Cellular and molecular life sciences 31 (1975), S. 1285-1287 
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    Notes: Summary Three sporeless mutants ofBacillus thuringiensis, 2 derived from var.thuringiensis and 1 from var.sotto were selected after mutagenic treatment. They were completely lacking in ability to form spores, yet maintained intact insecticidal activity.
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    Cellular and molecular life sciences 31 (1975), S. 1290-1294 
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    Notes: Summary Larvae of both species start discharging at 8 days.Eigenmannia immediately produces pulses similar to those of the adult.Marcusenius however, possesses a characteristic larval discharge 20 times longer and of opposite polarity to the adult discharge which appears on Day 40.
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    Cellular and molecular life sciences 31 (1975), S. 1296-1298 
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    Notes: Summary The circadian change of oral temperature in 26 subjects was compiled for December, March and June. Average peak time delays up to 70 min, and a reduced daytime temperature rise were found in June compared with December.
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    Notes: Summary In vitro isometric contractile tension was measured in heart and skeletal muscle in 3 groups of mice: 1. a control group, 2. a group maintained for 27 weeks on 20% alcohol, and 3. a group whose fluid intake was restricted to the extent equaling that which occurred in the alcohol treated animals. Results showed a reduction in cardiac twitch tension in both the alcohol and fluid restricted group, as compared to normal controls. We therefore consider that dehydration per se may play an important role in the etiology of alcoholic cardiomyopathy.
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    Cellular and molecular life sciences 31 (1975), S. 1306-1308 
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    Notes: Summary Furosemide added to the Ringer solution bathing the external side of the isolated skin ofLeptodactylus ocellatus increased the PD and SCC and inhibited both active chloride influx and passive chloride efflux. The action on chloride permeability is thought to contribute to the diuretic effect of the drug.
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    Cellular and molecular life sciences 31 (1975), S. 1250-1251 
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    Notes: Summary A sesquiterpene-substituted 4-hydroxybenzoic acid, zonaroic acid (5), is described from the brown seaweedDictyopteris undulata (=zonarioides). The absolute stereochemistry in the zonarol (1)-chromazonarol (2) and zonaroic acid (5) series has also been defined. The occurrence of5 along with zonarol (1), the corresponding sesquiterpene-substituted hydroquinone, suggests that 4-hydroxybenzoic acid is the ring precursor as in ubiquinone biogenesis.
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    Cellular and molecular life sciences 31 (1975), S. 1254-1255 
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    Notes: Summary [18F]-5-fluoro-Dopa is a substrate for dopa decarboxylase of kidney and brain. Its potential use in brain studies is proposed.
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    Cellular and molecular life sciences 31 (1975), S. 1314-1315 
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    Notes: Summary Oscillations on the concentrations of cyclic nucleotides occurred during spontaneous rhythmic contractions in rat uterus. The levels of cyclic GMP and cyclic AMP were highest at the beginning of the contraction respectively the relaxation.
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    Cellular and molecular life sciences 31 (1975), S. 1319-1320 
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    Notes: Summary Six h after oral administration of carbon tetrachloride, the turnover of14CH3 from injected Methionine-Methyl-14C in microsomal lipids is increased in comparison with the turnover in microsomal proteins.
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    Notes: Summary The lumenal surface coat of the rat oviducts and uterine horns have been histochemically characterized at prepuberty, estrous cycle, castration, hormone replacement and pseudopregnancy. Under the EM, the coat was made up of filamentous and globular structures. Histochemical variations suggested that coat components are under endocrine control.
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    Cellular and molecular life sciences 31 (1975), S. 1464-1465 
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    Notes: Summary The ultrastructural comparison between E and EA rosettes showed that, in the former, the rosetting lymphocytes are mostly round in shape and their interaction with sheep erythrocytes only consists of limited areas of membrane contact, in the latter, rosetting lymphocytes are mostly in the shape of uropods and surrounding ox red cells show pseudopods protruding towards the lymphocyte and coming into contact with it.
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    Cellular and molecular life sciences 31 (1975), S. 1414-1415 
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    Notes: Summary The sulfate uptake ofLemna minor L. is very rapidly inhibited by SO2-concentrations of 0.15, 0.32 and 0.61 ppm. The sulfate concentration in the plant material is increased. At least 40% of the total sulfur in the organisms origins from SO2.
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    Cellular and molecular life sciences 31 (1975), S. 169-170 
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    Notes: Zusammenfassung Es werden neue Befunde beigebracht, die für die Bildung von Superoxyd-Radikal durch DMPH4, ein biologisch wichtiges Pterinderivat, sprechen.
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    Cellular and molecular life sciences 31 (1975), S. 177-180 
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    Notes: Résumé Les fibroblastes humains utilisent une quantité de glucose plus grande pendant leur croissance logarithmique que dans leur phase stationnaire. Les cultures à passage tardif consomment plus de glucose par cellule que les cultures à passage hâtif sans égard à la phase. Ce système doit être utile pour rechercher les altérations métaboliques au cours du vieillissement cellulaire et pour découvrir la base biochimique de certaines maladies dépendant de l'âge.
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    Cellular and molecular life sciences 31 (1975), S. 1445-1447 
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    Notes: Summary The triglyceride biosynthesis which occurs in freshly secreted goat skim milk can be localized predominantly to large (1–8 μm) pieces of membrane-bounded cytoplasm. These contain the usual cytoplasmic organelles (but no nucleus) plus one or more large lipid droplets.
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    Notes: Summary In rats dehydrated for 48 h and injected intraventricularly withl-cysteine-35S-hydrochloride, the specific activity of TCA-precipitable material, both in the hypothalamus and neurohypophysis, was found to diminish under reserpine treatment.
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    Cellular and molecular life sciences 31 (1975), S. 298-299 
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    Notes: Riassunto Lo studio dell'ereditabilità di un carattere metrico (la lunghezza del mastax) e le relative esperienze di selezione dimostrano l'origine genetica della variabilità fenotipica riscontrabile in ceppi partenogenetici diAsplanchna sieboldi (Rotatoria). I risultati ottenuti suggeriscono un'interpretazione analoga per il ciclo sessuale e la ciclomorfosi.
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    Cellular and molecular life sciences 31 (1975), S. 220-221 
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    Notes: Résumé Le cervelet des souris hétérozygotes de la mutation «lurcher» (Lc) présentent des anomalies. Il est réduit et déformé, en particulier l'uvula vermis. On peut détecter ces anomalies chez le nouveau-né de 3 jours avant l'apparition des aberrations du comportement.
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    Cellular and molecular life sciences 31 (1975), S. 227-228 
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    Notes: Zusammenfassung In einer Organkultur von Extremitätenknospen (Mäuse-Embryonen Tag 11) gelingt es bereits nach Gaben von 0,01 μg/ml Actinomycin-D in den ersten 24 h die Bildung der Knorpelanlagen von Scapula und Humerus zu unterdrücken, also Dysmelien oder Phokomelien in vitro zu erzeugen. Dieses Modell scheint zur in vitro-Testung von teratogenen Substanzen geeignet zu sein.
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    Cellular and molecular life sciences 31 (1975), S. 271-273 
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    Notes: Zusammenfassung Es wird gezeigt, dass die normale proteolytische Tätigkeit von stimulierten peritonealen Makrophagen der Maus durch das Benzo-pyron-Cumarin in vitro beträchtlich erhöht wird.
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    Cellular and molecular life sciences 31 (1975), S. 354-356 
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    Notes: Zusammenfassung Die zelluläre Lokalisation der Aufnahme von3H-NA und3H-5HT in den Hirnstamm von Ratten wurde am Modell der Nervengewebskultur untersucht. Im Gegensatz zu den Aminosäure-Transmittern, welche in Neurone und Gliazellen aufgenommen werden, zeigen Monoamine nur eine Aufnahme in Zellkörper und Fortsätze von Neuronen, nicht jedoch in Gliazellen. Es besteht eine Korrelation zwischen den Ergebnissen von fluoreszenzmikroskopischen Versuchen und unseren autoradiographischen Untersuchungen.
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    Cellular and molecular life sciences 31 (1975), S. 358-360 
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    Notes: Riassunto È esaminato l'effetto di sette idrocarburi policiclici, a diverso potere oncogeno, sulla sintesi del DNA nel timo, milza, midollo e fegato rigenerante di ratto. Il DMBA è inibente in tutti i tessuti esaminati, come pure il 1,2,3,4-DBA. Il BP ha un notevole effetto solo sul fegato rigenerante mentre il 1,2,3,4-DBA é più efficace dell'1,2,5,6-DBA in ogni caso. Non é stata stabilita una correlazione tra il potere oncogeno delle sostanze esaminate e la inibizione della sintesi del DNA.
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    Notes: Zusammenfassung Von den im Schneckenhirn (Helix pomatia) wahrscheinlich als Neurotransmitter wirkenden Substanzen führen Dopamin und Acetylcholin zu einem erhöhten Einbau von32P in Phospholipide; Serotonin zeigt eher einen gegenteiligen Effekt und Noradrenalin bleibt ohne Einfluss. Phosphatidylinositol weist die höchste Einbaurate auf. Die Resultate unterstreichen die Bedeutung von Dopamin, Acetylcholin und Serotonin als Neurotransmitter im Schneckenhirn und deren Einfluss auf den Metabolismus von Membranphospholipiden.
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    Cellular and molecular life sciences 31 (1975), S. 365-367 
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    Notes: Zusammenfassung In den lymphoiden Zellen eines an chronischer lymphatischer Leukämie und Lymphosarcoma leidenden Patienten wurden cytoplasmische, Haemosiderin enthaltende und von Einzelmembranen umgebene Einschlusskörper gefunden. Es ist ungewiss, ob diese Erscheinung erhöhter phagocytischer Aktivität oder dem Auftreten anomaler peripherer erythroider Zellen im peripheren Blut zuzuschreiben ist.
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    Cellular and molecular life sciences 31 (1975), S. 191-193 
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    Notes: Riassunto L'esposizione di giovani ratti e di ratti anziani ad uno stress cronico «ambientale» (stimolazione ottica, acustica e meccanica) ha provocato una diminuzione dell'attività monoamino ossidasica (MAO) cerebrale ed epatica. L'attività MAO si è rinormalizzata entro 7 giorni dall'ultima stimolazione, sia nei ratti giovani che nei vecchi. Viene pertanto suggerita l'assenza di differenze legate all'età, nella sensibilità delle MAO a questo tipo di stress.
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    Cellular and molecular life sciences 31 (1975), S. 383-384 
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    Notes: Résumé Nous avons étudié les effets de la mélatonine et de la sérotonine sur le métabolisme du14C-glucose dans le tissue adipeux du lapin. La mélatonine semble inhiber la synthèse des acides gras et l'oxidation du glucose alors que la sérotonine est sans action. La mélatonine et la sérotonine empêchent l'incorporation du14C-glucose dans la fraction glycéride-glycérol.
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    Cellular and molecular life sciences 31 (1975), S. 389-390 
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    Notes: Riassunto E' stata realizzata una metodica elettroforetica, su strati sottili di Sephadex, per la determinazione del peso molecolare medio di alcuni mucopolisaccaridi. E' stata osservata una relazione lineare tra il Log. P.M. ed il rapportode/do ottenuto su Sephadex-G100 e su Sephadex-G10.
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    Cellular and molecular life sciences 31 (1975), S. 404-406 
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    Notes: Résumé Le cervelet contient des quantités plus grandes d'ATP, d'ADP et de nucléotides totaux que le lobe frontal du cerveau ou la moelle cervicale. Ces différences ne sont pas trouvées avec l'AMP. Le contenu en glycogène, en glucose et en lactate est plus grand dans la moelle cervicale que dans le cervelet et dans le lobe frontal.
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    Cellular and molecular life sciences 31 (1975), S. 209-212 
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    Notes: Zusammenfassung Nachweis, dass das lokaleShwartzman-Phänomen in Kaninchen durch intradermale oder i.v. Gabe von Pepstatin, einem sauren Proteinase-Hemmer, oder von Sojabohnen-Trypsin-Hemmer kurz vor der auslösenden Injektion von bakteriellem Endotoxin unterdrückt werden kann.
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    Cellular and molecular life sciences 31 (1975), S. 218-220 
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    Notes: Zusammenfassung Nachweis, dass die nach Halothan eingetretene Verminderung der Kontraktilität des Myokards durch Lactat oder Acetat verhindert werden kann. Das Ergebnis stützt die Hypothese, Halothan hemme die Aufnahme von Glykose oder beeinträchtige deren Verwertung.
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    Cellular and molecular life sciences 31 (1975), S. 225-227 
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    Notes: Riassunto Abbiamo esaminato l'appaiamento a distanza dei 12 cromosomi omologhi nella tarda profase e metafase ovocitaria inTisbe holothuriae evidenziando una ultrastruttura non prima descritta in letteratura.
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    Cellular and molecular life sciences 31 (1975), S. 145-145 
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    Notes: Zusammenfassung Isolierung und Strukturzuteilung für ein Alkaloid ausColeomegilla maculata (Coleoptera: Curculionidae).
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    Cellular and molecular life sciences 31 (1975), S. 233-234 
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    Notes: Summary On electron microscopy, platelets exposed to chloroquine exhibit no abnormality, except for surface connecting system. However, when platelets were labelled with14C serotonin, there was liberation of a large amount of radioactivity which is inhibited when the extracellular concentration of serotonin is increased. It appears that chloroquine is a competitive inhibitor of serotonin uptake by platelets.
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    Cellular and molecular life sciences 31 (1975), S. 238-239 
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    Notes: Résumé La technique directe de l'immunofluorescence a permis de mettre en évidence dans un ganglion lymphatique adjacent à la tumeur cancéreuse du rectum la présence de nombreuses cellules sécrétant de IgG monoclonal.
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    Cellular and molecular life sciences 31 (1975), S. 244-245 
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    Notes: Résumé La quantité d'125I absorbée dans le médium par les glandes thyroïdes incubées in vitro ne fut pas sensiblement affectée par la variation physiologique de la concentration du magnésium dans le médium, ni par la quantité de magnésium absorbée par les rats avant leur mort.
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    Notes: Résumé L'administration du pimozide, un bloqueur spécifiquement dopaminergique, à des rats intacts et hypophysectomisés, a pour résultats une augmentation du CRF hypothalamique, une diminution concomitante du poids pituitaire ainsi qu'une réaction réduite à l'≪ether stress≫. Ces données indiquent l'existence d'une mécanisme dopaminergique dans le contrôle de libération du MECRF.
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    Cellular and molecular life sciences 31 (1975), S. 256-258 
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    Notes: Zusammenfassung Feststellung, dass die eindimensionale Diffusions-Methode eine sensitive, einfache und reproduzierbare Technik zur Bestimmung der Veränderungen der fibrinolytischen Aktivität bei Ratten ist.
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    Cellular and molecular life sciences 31 (1975), S. 280-281 
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    Notes: Résumé On a étudié le contenu en cuivre et en zinc du sérum et de l'urine des malades infectés par la bilharzie, la plupart avec cirrhose du foie. On a trouvé une augmentation notable du zinc et du cuivre dans le sérum et une augmentation élevée du zinc dans l'urine.
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    Notes: Zusammenfassung Eine Synthese von Scotophobin mit klassischen Methoden ergab ein Produkt, das sich vom natürlichen Peptid hinsichtlich seiner biologischen, chromatographischen und physiologischen Eigenschaften unterschied. Es wird daraus gefolgert, dass die für das natürliche Produkt vorgeschlagene Strukturformel nicht korrekt ist.
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    Cellular and molecular life sciences 31 (1975), S. 482-483 
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    Notes: Résumé L'actinomycine D est solubilisée dans un milieu aqueux par une technique de congélation suivie de dégel, ce qui permet d'atteindre des concentrations de 1 mg/ml à 4°C et de 0.5 mg/ml à la température du laboratoire. Pour obtenir une absorption rapide de l'actinomycine D les concentrations ne doivent pas dépasser 0.25 mg/ml.
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    Cellular and molecular life sciences 31 (1975), S. 491-493 
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    Notes: Zusammenfassung Das mikroskopische Bild des schnell wachsenden Keratoakanthoms beim Kaninchen wird durch Vitamin A und Puromycin wesentlich beeinflusst und verändert.
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    Cellular and molecular life sciences 31 (1975), S. 496-498 
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    Notes: Zusammenfassung Es wird über elektrophoretische Untersuchungen zum mikrosomalen Enzym Hexose-6-Phosphat-Dehydrogenase (H6PD) aus menschlichen Leukocyten, Plazentagewebe und Leber bei Gesunden und Kranken berichtet. Ferner wird durch Analyse des Enzyms H6PD bei zwei verschiedenen Glukose-6-Phosphate-Dehydrogenase (G6PD) Phänotypen gezeigt, dass die beiden Enzyme H6PD und G6PD beim Menschen nicht gemeinsamer genetischer Kontrolle unterliegen.
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    Cellular and molecular life sciences 31 (1975), S. 503-504 
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    Notes: Zusammenfassung Behandlung von Ampicillin oder Ampicilloylsäure mit Uranylacetat in der Wärme bei pH 5.2 ergibt ein stabiles fluoreszierendes Produkt. Ausnützung dieser Tatsache und der proteinfällenden Wirkung von Uranylacetat ergibt eine einfache Methode zur Ampicillinbestimmung im Serum mit einer Empfindlichkeit von etwa 0.1 μg/ml. Kombination mit Penicillinasebehandlung erlaubt, Ampicillin in Gegenwart von Ampicilloylsäure zu messen.
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    Cellular and molecular life sciences 31 (1975), S. 520-521 
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    Notes: Zusammenfassung Cannabinol (CBN) ist als Metabolit desΔ 1-Tetrahydrocannabinols und desΔ 6-Tetrahydrocannabinos im Rattenblut erwiesen worden. Die Gipfel-Konzentration von CBN wird 40 sec nach der i.v. Injektion erreicht. Der mögliche Beitrag von CBN zum Cannabis-Effekt wird diskutiert.
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    Cellular and molecular life sciences 31 (1975), S. 526-528 
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    Notes: Zusammenfassung Die Umweltstabilität von 29 strahleninduzierten Mutanten und 11 Kulturvarietäten wird anhand der Methode vonEberhart undRussell 2 untersucht. Die Mutanten werden auf Grund der Versuchsergebnisse in stabile und angepasste klassiert.
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    Cellular and molecular life sciences 31 (1975), S. 531-532 
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    Notes: Zusammenfassung Chromatinhaltige feulgenpositive Bläschen wurden im Cytoplasma der Erythrocyten vonCyprinus carpio gefunden. Sie haben ihren Ursprung in den unmittelbar an der Kernmembran anliegenden Mitochondrien, die während der Chromatinaufnahme allmählich ihre Struktur verlieren.
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    Cellular and molecular life sciences 31 (1975), S. 539-540 
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    Notes: Zusammenfassung Bei der Kopulation der GrillePlebeiogryllus guttiventris werden mindestens 2 unabhängige Stimuli wirksam, welche Oviposition und Eiproduktion beeinflussen. Weder künstliche Spermatophorenübertragung noch Kopulation mit kastrierten Männchen stimuliert die Oviposition; letztere bewirkt aber erhöhte Eiproduktion. Künstliche Übertragung von Spermatophoren in hungernde, virgine Weibchen reduziert die Eiproduktion und bewirkt eine Lebensverlängerung.
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    Cellular and molecular life sciences 31 (1975), S. 545-546 
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    Notes: Zusammenfassung Glasmikroelektroden, mit 3M KCl gefüllt, wurden verschiedenartig präpariert und ihr Spitzenpotential mit 0.01∼3.0M KCl gemessen. Die Resultate sprechen dafür, dass die negativen elektrischen Ladungen, an der Glaswand fixiert, eine entscheidende Rolle bei der Entstehung des Spitzenpotentials spielen.
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    Cellular and molecular life sciences 31 (1975), S. 380-382 
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    Notes: Zusammenfassung Die Isolierung einzelner Fraktionen der Hypophyse, im besonderen der Mittellappenanteile ist kompliziert und es wurden daher Kulturen von Rinderhypophysen angelegt, in welchen ACTH und MSH vorkommt. Im Zusammenhang mit dem Transportsystem wird festgestellt, dass dem Mittellappen eine gleich wichtige Funktion zukommt wie dem Vorder- oder Hinterlappen und dass jener nicht als ein Segment des Hinterlappens aufgefasst werden kann.
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    Cellular and molecular life sciences 31 (1975), S. 534-537 
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    Notes: Zusammenfassung In der Deckhaut des sexuell gereiften Weibchens vonA. pallipes treten Porengruppen auf. Diese Poren überlagern die Schleimdrüsen, die während des Laichens grosse mengen Schleim produzieren. Die Poren und Drüsen befinden sich auf dem Unterleib und den Pleopoden; die Oosetae, die zur Eiablagerung dienen, befinden sich ebenfalls an diesen Stellen. Dies sind sekundäre sexuelle Charakteristika, die eng mit dem Legen und der Ablage der Eier verbunden sind.
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    Cellular and molecular life sciences 31 (1975), S. 543-544 
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    Notes: Résumé Dans l'hémolymphe des escargots (Helix pomatia) traités avec le CO2 le calcium ionique augmente et le pH diminue de telle façon que le produit [Ca++]·[CO 3 = ] ainsi que l'association du calcium avec l'hémocyanine restent à peu près constant. Le temps requis pour attcindre une situation stable est reglé par l'entrée lente du CO2. Après injection de CaCl2, [Ca++] et [HCO 3 − ] diminuent, ainsi que le produit [Ca++]·[CO 3 = ].
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    Cellular and molecular life sciences 31 (1975), S. 550-550 
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    Notes: Zusammenfassung Nachweis, dass die Substanz ICI 66082 eine β-Rezeptoren blockierende Wirkung in der Submaxillarisdrüse von Ratten hat. Weiterhin zeigen die Versuche, dass ICI 66082 ohne partielle Agonistenaktivität zu sein scheint und auch keine lokalanaesthetische Wirkung hat.
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    Cellular and molecular life sciences 31 (1975), S. 562-564 
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    Notes: Zusammenfassung Nach Behandlung mit dem Diaminoxidase (DAO)-Hemmer Aminoguanidin wurden Appetitzunahme, vermehrte Nahrungsaufnahme und Gewichtszunahme sowohl bei einem Krebspatienten als auch bei Ratten beobachtet, wobei der Mechanismus des Effektes unklar blieb. Die Anreicherung der Droge sowie die Hemmung der DAO in den Geweben wurde gemessen.
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    Cellular and molecular life sciences 31 (1975), S. 573-575 
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    Notes: Zusammenfassung Bei normaler Ernährung und täglichem Trinken von beliebigen Mengen 40% igem Zuckerrohrschnaps wurden bei weissen Laboratoriumsratten diverse anatomische und ultrastrukturelle Lungenveränderungen nachgewiesen: Hypertrophie und Hyperplasie der Pneumocyten vom Typ 2, Anhäufung intraalveolärer Makrophagen und Verdickung der Alveolarwände.
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    Cellular and molecular life sciences 31 (1975), S. 444-445 
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    Notes: Zusammenfassung Nachweis der antimikrobiellen Wirkung der bekannten Neuroleptika Chlorpromazin, Levomepromazin und Promethazin, wobei Chlorpromazin die beste bakterizide wirkung hatte. Die grampositiven Bakterienstämme waren empfindlicher gegen Chlorpromazin als die gramnegativen, während Chlorpromazin keinerlei Wirkung auf die Vermehrung vonPseudomonas aeruginosa hatte.
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    Cellular and molecular life sciences 31 (1975), S. 586-587 
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    Notes: Riassunto È stata evidenziata una correlazione fra caratteristiche istochimiche e composizione biochimica del mesenchima e l'instaurarsi del differenziamento dell'epitelio nella cute di pollo sia in vitro, in espianti prelevati al 6° giorno di incubazione e mantenuti in terreno nutritizio contente siero, che in vivo.
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    Cellular and molecular life sciences 31 (1975), S. 591-593 
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    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Ein gewisser Grad von Makrophagenaktivierung, gemessen an der Fähigkeit der Listerien-Elimination, wird auch in adult thymektomierten, mit Knochenmark rekonstituierten Mäusen sowie in nude/ nude-Mäusen beobachtet und daraus der Schluss gezogen, dass die Makrophagenaktivierung nicht unter allen Umständen mit der Anwesenheit von T-Lymphozyten verknüpft sein muss.
    Type of Medium: Electronic Resource
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