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  • Bone
  • Drosophila
  • Springer  (6)
  • Blackwell Publishing Ltd
  • International Union of Crystallography
  • Springer Nature
  • 2020-2022
  • 1975-1979  (6)
  • 1975  (6)
Collection
Publisher
  • Springer  (6)
  • Blackwell Publishing Ltd
  • International Union of Crystallography
  • Springer Nature
Years
  • 2020-2022
  • 1975-1979  (6)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Biochemical genetics 13 (1975), S. 273-282 
    ISSN: 1573-4927
    Keywords: Drosophila ; scarlet mutant ; xanthurenic acid ; 3-hydroxykynurenine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract 3-Hydroxykynurenine is virtually absent from st larvae but accumulates during adult development in the puparium. Over the period of adult emergence, the accumulated 3-hydroxykynurenine is excreted so that st adults contain none. Larvae of st fed on tryptophan-C 14 medium produce labeled 3-hydroxykynurenine, at a reduced rate, perhaps, compared to wild type. Xanthurenic acid levels in st pupae are similar to those in wild type. Thus the failure of st larvae to accumulate 3-hydroxykynurenine does not seem to be due either to an inability to synthesize this compound or to an excessive rate of its conversion to xanthurenic acid. Rather, it appears that the mechanism of 3-hydroxykynurenine storage during larval life is defective, so that this compound is excreted at an abnormally high rate. The inability of the pigment cells of the eyes of st to synthesize xanthommatin may result from a similar defect in their ability to take up or store 3-hydroxykynurenine.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Biochemical genetics 13 (1975), S. 353-356 
    ISSN: 1573-4927
    Keywords: suppression ; Drosophila ; phenol oxidase ; speck
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract A marked decrease in the amount of the A2 component of phenol oxidase occurs in the speck locus of Drosophila melanogaster. The amount of A2 in speck is restored to a normal amount in the presence of the suppressor mutant, su(s) 2.
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  • 3
    ISSN: 1573-4927
    Keywords: allozymes ; Drosophila ; populations ; Michaelis constant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract A biochemical comparison was made between α-glycerophosphate dehydrogenase allozymes from Drosophila melanogaster. Enzymes extracted from the three major genotypes were indistinguishable in terms of their pH optima and thermal stabilities. Distinctive differences were observed for three parameters; temperature dependence of specific activity, temperature dependence of Km, and reaction rate constancy over a physiological temperature range. These results are discussed in terms of a model of balancing selection and the existence of spatial and temporal allele frequency clines in natural populations.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Biochemical genetics 13 (1975), S. 85-108 
    ISSN: 1573-4927
    Keywords: phenol oxidase ; Drosophila ; activation ; cascade
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Our earlier evidence concerning the complexity of the activation process for Drosophila phenol oxidase has been confirmed by separation and purification of six proteins involved. This is a minimal number required in a reaction series or cascade to yield active enzyme, and at least two more proteins are known to be involved. A simpler system involving only the last step with one precursor and one activation as has been reported in the literature is consistent with the cascade picture, but the whole complex system must be considered when dealing with genetic and developmental regulation of pigmentation and sclerotization. Details are given for partial or complete purification of six of the proteins involved and evidence for their modes of interaction is presented.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Behavior genetics 5 (1975), S. 255-267 
    ISSN: 1573-3297
    Keywords: genetic selection ; Drosophila ; phototaxis ; geotaxis ; interspecific difference
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract The initial experimental population ofDrosophila persimilis was photopositive and slightly geonegative. In this respect, the initial population ofD. persimilis differed from the experimental population ofD. pseudoobscura, described by others, which was close to photo- and geotactic neutrality. InD. persimilis, as inD. pseudoobscura, photo- and geotactic selection was efficient in both positive and negative directions. InD. persimilis, unlike inD. pseudoobscura, the responses to geotactic and phototactic selection were clearly asymmetrical. As a result of such responses, selection practically eliminated interspecific difference in geotaxis and almost eliminated interspecific difference in phototaxis. The realized heritabilities of photo- and geotaxis over the first ten generations of selection inD. persimilis are between 6 and 7%. Practically, these heritabilities inD. persimilis have the same value, whereas inD. pseudoobscura the heritabilities are clearly different. These findings suggest thatD. persimilis differs considerably fromD. pseudoobscura in the composition of the genes determining photo- and geotactic behavior, most probably reflecting adaptations of these sibling species to different ecological niches. However, both species are capable of reacting quickly to external stresses by reorganizing their gene pools and by correspondingly changing their behavior.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Behavior genetics 5 (1975), S. 373-379 
    ISSN: 1573-3297
    Keywords: assortative mating ; rare-male advantage ; frequency-dependent selection ; sexual vigor ; inbreeding ; Drosophila
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Frequency-dependent sexual selection was studied using three geographically isolated strains ofDrosophila melanogaster. The Oregon-R and Canton-Special wild-type strains were essentially homogeneous, having been maintained in laboratories since 1925; the wild Macomb strain was relatively genetically heterogeneous, having been collected in September 1972, immediately prior to this investigation. All possible double combinations of the three strains were placed in separate chambers of a modified Elens-Wattiaux observation apparatus at ratios of 5∶20, 12∶12, and 20∶5. Allowing 2 hr observation time for each chamber, data were collected to detect mating preference between these strains. There was no sexual isolation between the strains. However, frequency dependence, where rare males have a definite mating advantage in a population, was exhibited by the strains studied. Sexual vigor appeared to be a factor when the heterogeneous Macomb strain was mated to either of the two homogeneous strains in equal numbers.
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