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  • genetics  (12)
  • Immunocytochemistry
  • Springer  (13)
  • American Association for the Advancement of Science
  • 1990-1994
  • 1970-1974  (13)
  • 1950-1954
  • 1974  (13)
Collection
Keywords
Publisher
  • Springer  (13)
  • American Association for the Advancement of Science
Years
  • 1990-1994
  • 1970-1974  (13)
  • 1950-1954
Year
  • 1
    Electronic Resource
    Electronic Resource
    Sunflower alcohol dehydrogenase: ADH1 genetics and dissociation-recombination (1974)
    Springer
    Biochemical genetics 11 (1974), S. 17-24 
    Details
    ISSN: 1573-4927
    Keywords: Helianthus annuus ; alcohol dehydrogenase ; isozymes ; dissociation-recombination ; genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The composite alcohol dehydrogenase zymogram of sunflowers, Helianthus annuus, consists of 12 distinct bands. Genetic studies suggest that the slowest-moving three bands are allozymic dimers. They are controlled by a gene designated Adh 1 having two codominant alleles, Adh 1 F and Adh 1 S . The heterozygote produces three bands as expected with a dimer molecule, while the homozygotes produce but one band each, consisting of FF or SS homodimers. The genetic evidence is supported by dissociation-recombination experiments in which the homodimers were separated and allowed to rejoin as parental homodimers and the hybrid heterodimer. Adh 1 FS was found in only three of 422 cultivar seeds of one collection out of about 70 (over 6000 individual seeds tested) and was seen only infrequently in the seven wild collections examined. Adh 1 SS has never been found in the cultivar collections studied and but rarely in the wild populations sampled.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00486615
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  • 2
    Electronic Resource
    Electronic Resource
    Kinetic characteristics of monoamine oxidase and serum cholinesterase in several related rat strains (1974)
    Springer
    Biochemical genetics 11 (1974), S. 309-317 
    Details
    ISSN: 1573-4927
    Keywords: genetics ; rat ; kinetics ; brain MAO ; serum ChE
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract This study was performed in order to delineate differences in kinetic enzyme characteristics of brain monoamine oxidase (MAO) and plasma cholinesterase (ChE) derived from the Walker-Walker (Fawn Hooded, FH) rat and from its putative ancestors, the Wistar (W) and Long-Evans (LE). As compared with the enzyme isolated from the other two strains, brain MAO from FH has both a higher V max and increased reaction rate at lower substrate concentrations. It may thus be described as a “more efficient” enzyme. This study confirms previous work which shows that plasma ChE activity of females is higher than that of males. Fluoride ion is a noncompetitive inhibitor of the Wistar ChE, is a competitive inhibitor of the FH enzyme, and has no effect on the LE enzyme. Dibucaine is a competitive inhibitor in all cases except one: ChE derived from the FH female is uncompetitively inhibited. A comparison of the inhibitor constants shows that FH ChE is more resistant to Dibucaine than is that of W, and that LE is the most sensitive. FH cholinesterase is twice as resistant to the action of fluoride as is the Wistar enzyme.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00485998
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  • 3
    Electronic Resource
    Electronic Resource
    Genetics of sunflower alcohol dehydrogenase: Adh 2 ,nonlinkage to Adh 1 and Adh 1 early alleles (1974)
    Springer
    Biochemical genetics 12 (1974), S. 385-392 
    Details
    ISSN: 1573-4927
    Keywords: Helianthus annuus ; alcohol dehydrogenase ; isozymes ; genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Alcohol dehydrogenase (ADH) isozymes in annual sunflowers (Helianthus annuus) are dimers whose subunits are produced by two genes, Adh 1 and Adh 2 .The codominant F and S alleles of Adh 1 produce the slower-migrating set of three isozymes. The faster-migrating set of three isozymes is controlled by Adh 2 , which also has at least two alleles, F and S. Hybridization experiments indicated that the Adh 2 alleles segregate in expected Mendelian fashion and that Adh 1 and Adh 2 are not linked. A third common 1-locus allele is designated early (E) because when homozygous it results in a blank at the 1FF isozyme position in mature seeds, but in developing seeds produces a normal-appearing band at the 1FF position. Hybridization studies showed that the early alleles segregated normally. Correlation between genotype and presence or absence of isozymes electrophoretically intermediate between those of Adh 1 and Adh 2 suggests that four intergenic isozymes may be formed as a result of dimerization of the four basic subunits. Studies of zymograms of developing seeds suggest that the remaining but inconstant zymogram bands are mature seed isozymes which have altered charges during early morphogenesis and thus are developmental artifacts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00486643
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  • 4
    Electronic Resource
    Electronic Resource
    Luteinizing hormone —Releasing hormone (LH-RH) pathway of the rat hypothalamus revealed by the unlabeled antibody peroxidase-antiperoxidase method (1974)
    Springer
    Cell & tissue research 153 (1974), S. 211-217 
    Details
    ISSN: 1432-0878
    Keywords: Luteinizing hormone-releasing hormone ; Hypothalamus ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Utilizing the unlabeled antibody enzyme method, we report the distribution of hypothalamic elements immunoreactive with antibodies to luteinizing hormone-releasing hormone (LH-RH) in the rat. Immunostained elements, resembling neural processes, were distributed along a pathway corresponding to the tuberoinfundibular tract which appeared to terminate near vascular elements in the external layer of the preand post-infundibular median eminence. No cell bodies stained specifically for LH-RH. Similar topographic arrangements were noted (in coronal and sagittal sections) in diestrous females, ovariectomized females and a hypophysectomized male. The same results were obtained with three different preparations of antisera to LH-RH. Our studies agree with those of other investigators using immunohistochemical techniques as well as with localization studies of LH-RH in the hypothalamus using bioassay and radioimmunoassay. Our results suggest that the unlabeled antibody enzyme technique will have unique value for identifying and tracing fiber systems related to specific functions within the hypothalamus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226609
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  • 5
    Electronic Resource
    Electronic Resource
    Intellectual development of children from interracial matings: Performance in infancy and at 4 years (1974)
    Springer
    Behavior genetics 4 (1974), S. 83-90 
    Details
    ISSN: 1573-3297
    Keywords: race ; intelligence ; interracial ; infancy ; genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Psychological tests at 8 months and at 4 years of age were administered to 129 children of interracial (Negro-white) matings in the Collaborative Study. These interracial children were divided into two groups, depending on whether the mother was the white or the Negro partner. Stanford-Binet IQs of the 4-year-old children of white mothers averaged approximately 9 points higher than those with Negro mothers (p〈0.01). The only behavioral difference on the Bayley Scales of Infant Development at 8 months of age was in favor of the interracial children of Negro mothers (p〈0.05). The results are interpreted as supporting the hypothesis that postnatal environmental factors make a very substantial contribution to racial differences in intelligence test performance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066706
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  • 6
    Electronic Resource
    Electronic Resource
    Genetic control of activity, preening, and the response to a shadow stimulus inDrosophila melanogaster (1974)
    Springer
    Behavior genetics 4 (1974), S. 317-329 
    Details
    ISSN: 1573-3297
    Keywords: genetics ; activity ; preening ; stimulation ; Drosophila melanogaster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Spontaneous locomotor activity, preening and the change in frequency of each in response to a shadow have been studied in Drosophila melanogaster by means of a time-sampling technique. The genetic control of these four behaviors was elucidated by application of biometrical genetic analysis. The genetic architecture for spontaneous activity indicated a history of natural selection for comparatively high activity. There was a tendency for both activity and preening to decrease in response to shadow stimulation. The genetic control indicates that this form of reaction is advantageous and suggests a relation to the avoidance of predation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066153
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  • 7
    Electronic Resource
    Electronic Resource
    Kinship correlations reported by Sir Cyril Burt (1974)
    Springer
    Behavior genetics 4 (1974), S. 1-28 
    Details
    ISSN: 1573-3297
    Keywords: Burt ; genetics ; intelligence ; relatives ; twins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract All the kinship correlations (and their sample sizes) reported over a period of 30 years by Sir Cyril Burt are presented in tabular form. The kinships include identical twins reared together and apart, fraternal twins, siblings, parent-child, grandparent-grandchild, cousins, and others, more rare types of relationships. Burt's statistical methods and the procedures for testing and obtaining “final assessments” of mental ability are fully described, and the final assessments for Burt's 53 monozygotic twins reared apart are given in full. Misprints and inconsistencies in some of the data are noted, and recommendations are made for the presentation and preservation of kinship data secured by future researchers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066704
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  • 8
    Electronic Resource
    Electronic Resource
    A genetic analysis of escape behavior in rats (1974)
    Springer
    Behavior genetics 4 (1974), S. 125-131 
    Details
    ISSN: 1573-3297
    Keywords: rats ; escape behavior ; genetics ; heterosis ; passive avoidance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Three strains of highly inbred rats and their derived F1 hybrid progeny were tested for escape latencies in a novel test situation at three ages. There were very highly significant differences in escape latencies between genotypes and between ages. There was also a very highly significant genotype by age interaction; the inbreds had increasing latencies with increasing age, whereas the hybrids did not. Heterosis was observed, and it was concluded that this behavioral heterosis was consistent with the hypothesis of selection for an intermediate optimum in latency to escape.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01065753
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  • 9
    Electronic Resource
    Electronic Resource
    Gene differences influencing visual system function and behavior (1974)
    Springer
    Behavior genetics 4 (1974), S. 165-170 
    Details
    ISSN: 1573-3297
    Keywords: visual system ; genetics ; behavior open field ; mice ; single gene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Behavioral differences between albino (cc) and pigmented (C−) mice are mimicked by animals homozygous for a recessive allele (p) 13 map units from thec locus. Electroretinograms forcc andpp animals are similar, showing greatly enhanced a- and b-waves compared to normals (C−). The behavioral and retinal physiology similarities of albino (cc) and dilute pigmented (pp) mice probably result from increased sensitivity to illumination. Recently reported decreased ipsilateral retinogeniculate projections characteristic ofcc animals may result from genotype — visual environment interactions rather than from pleiotropic effects of thec locus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01065757
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  • 10
    Electronic Resource
    Electronic Resource
    Severe and moderate language impairment: Evidence for distinctive etiologies (1974)
    Springer
    Behavior genetics 4 (1974), S. 331-345 
    Details
    ISSN: 1573-3297
    Keywords: language ; genetics ; environment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Forty-two children of at least normal nonverbal intelligence and with a diagnosis of “delayed speech” were subdivided into those having “moderate” and those having “severe” speech difficulties on the basis of the Illinois Test of Psycholinguistic Abilities. Parents of children with “severe” speech difficulties were of much higher social class, and the children were much more likely to have been exposed to potentially traumatic environmental influences than the “moderately” affected children. The “severely” affected probands were also much less likely than the “moderately” affected probands to have relatives with speech disturbances. These data indicate the heterogeneity of the diagnosis of “delayed speech” and suggest parallels to findings in the area of mental retardation, namely, that moderate deficiencies represent the lower end of the normal curve distribution from either a genetic or an environmental perspective, while severe deficiencies are the result of single genes or of serious environmental traumas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066154
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  • 11
    Electronic Resource
    Electronic Resource
    Aggression as a component of relative fitness in four inbred strains of mice (1974)
    Springer
    Behavior genetics 4 (1974), S. 373-381 
    Details
    ISSN: 1573-3297
    Keywords: aggression ; fitness ; strain of mice ; genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract In four separate experiments, male mice from the RF/J, BALB/cJ. DBA/2J, and C57BL/6J strains were grouped in a seminaturalistic environment with females from the C57BL/6J strain. Observations were made concerning the aggressive behavior of the different strains, and starch gel electrophoresis of the esterase III and hemoglobin proteins was used to determine paternity of the offspring. Results indicated that the most aggressive strain, RF/J, sired 95.6% of all offspring. Control groups indicated that the reproductive disadvantage of the BALB and C57 males could be explained in terms of differences in general fertilizing ability, the effects of grouping mice together, or pregnancy blockage. These factors alone were not sufficient to explain the disadvantage of the DBA males. Differences in fighting success may therefore be an important determinant of fitness differences between RF and DBA males.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066157
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  • 12
    Electronic Resource
    Electronic Resource
    Male mating speed as a component of fitness inDrosophila (1974)
    Springer
    Behavior genetics 4 (1974), S. 395-404 
    Details
    ISSN: 1573-3297
    Keywords: Drosophila ; mating speed ; fitness ; genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract From a survey of published data on the genusDrosophila, it is clear that male mating speed or male virility is probably the most important component of fitness. Rapid matings tend to be controlled by the male genotype, while the genotype of the female may assume importance for slower matings. Where data exist, male mating speed is subject to directional selection in the direction of rapid speed, as would be expected for an important component of fitness.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066159
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  • 13
    Electronic Resource
    Electronic Resource
    Differences in bitter taste perception in three strains of rats (1974)
    Springer
    Behavior genetics 4 (1974), S. 405-410 
    Details
    ISSN: 1573-3297
    Keywords: genetics ; rat ; taste ; cycloheximide ; PTC
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Micromolar concentrations of cycloheximide (CH) can be used to test for genetic differences in the ability to taste bitter substances. Three related strains of rats — Fawn-hooded, Long Evans, and Wistar — differ significantly in their ability to taste this substance, the former being unusually deficient in this respect. Wistar and Long Evans rats are able to perceive millimolar concentrations of phenylthiocarbamide (PTC) and 0.2 μM CH. FH animals are unable to detect millimolar PTC and first recognize CH when it is present in 1.5 μM concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066160
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