ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Histochemistry  (22)
  • pharmacokinetics
  • Springer  (28)
  • American Geophysical Union
  • Irkutsk : Ross. Akad. Nauk, Sibirskoe Otd., Inst. Zemnoj Kory
  • Krefeld : Geologischer Dienst Nordhein-Westfalen
  • Wiley
  • 2015-2019
  • 2005-2009
  • 1975-1979
  • 1970-1974  (28)
  • 1972  (28)
Collection
Keywords
Publisher
  • Springer  (28)
  • American Geophysical Union
  • Irkutsk : Ross. Akad. Nauk, Sibirskoe Otd., Inst. Zemnoj Kory
  • Krefeld : Geologischer Dienst Nordhein-Westfalen
  • Wiley
Years
  • 2015-2019
  • 2005-2009
  • 1975-1979
  • 1970-1974  (28)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Quantitative histochemistry of cartilage (1972)
    Springer
    Calcified tissue international 10 (1972), S. 49-57 
    Details
    ISSN: 1432-0827
    Keywords: Histochemistry ; Cartilage ; Enzymes ; Vitamin D ; Starvation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Résumé 1. La distribution quantitative de phosphatase alcaline et de déshydrogénas eglucose-6-phosphate dans les zones hypertrophiques, en voie de prolifération du cartilage de rats rachitiques, pendant la cicatrisation induite par l'administration de vitamin D ou par jeun prolongé, est étudiée. 2. L'activité en phosphatase alcaline de la zone hypertrophique est environ triple de celle de la zone de prolifération du rat sevré normal et environ quadruple de celle des rats rachitiques. 3. Apres administration d'une seule dose de vitamine D (8000 unités), il se produit une augmentation significative de l'activité en phosphatase alcaline de la a zone en voie de prolifération. Une augmentation moins nette est observée dans la zone de prolifération de rats ayant jeuné 48 heures. 4. On observe une diminution significative de l'activité en phosphatase alcaline de la partie centrale de la zone hypertrophique de cartilage aprés traitement a la vitamine D. Une telle diminution n'a pas été observée chez le rat qui jeûne. 5. Chez le rat sevré normal, l'activité en déshydrogénase glucose-6-phosphate (G-6-PDH) est plus élevée dans la zone de prolifération que dans la zone hypertrophique. Chez le rat rachitique non traité, le contenu en enzyme est à peu pres identique dans les deux zones. 6. Apres traitement a la vitamine D, on note une décroissance nette de l'activité en G-6-PDH. Une telle décroissance n'est pas observée chez le rat qui jeûne.
    Abstract: Zusammenfassung 1. Diese Arbeit beschreibt die quantitative Verteilung der alkalischen Phosphatase und der Glucose-6-Phosphat-Dehydrogenase in proliferierenden und hypertrophischen Zonen von rachitischem Rattenknorpel während der durch Vitamin D-Gabe hervorgerufenen Heilung oder während der Mangeldiät. 2. Die Aktivität der alkalischen Phosphatase in der hypertrophischen Zone war etwa dreimal so groß wie in der proliferierende Zone der normalen entwöhnten Ratte und etwa viermal so groß bei den rachitischen Ratten. 3. Nach einer einmaligen Vitamin D-Gabe (8000 i.E) erfolgte eine signifikante Erhöhung der alkalischen Phosphatasen-Aktivität in der proliferierenden Zone. Eine weniger signifikante Erhöhung wurde in der proliferierenden Zone von Ratten festgestellt, welche 48 Std gefastet hatten. 4. Nach Vitamin D-Behandlung erfolgte eine signifikante Abnahme der alkalischen Phosphatasen-Aktivität in der mittleren Region der hypertrophischen Zone des Knorpels. Bei den fastenden Ratten wurde keine solche Abnahme beobachtet. 5. Bei der normalen entwöhnten Ratte war die Aktivität der Glucose-6-Phosphat-Dehydrogenase (G-6-PDH) größer in der proliferierenden als in der hypertrophischen Zone. Bei der unbehandelten rachitischen Ratte war der Enzymgehalt in beiden Zonen etwa gleich. 6. Nach Vitamin D-Behandlung erfolgte eine merkliche Abnahme der G-6-PDH-Aktivität. Bei der fastenden Ratte wurde keine solche Abnahme beobachtet.
    Notes: Abstract 1. The quantitative distribution of alkaline phosphatase and glucose-6-phosphate dehydrogenase in proliferating and hypertrophic zones of rachitic rat cartilage during healing induced by vitamin D administration or starvation is presented. 2. Alkaline phosphatase activity in the hypertrophic zone is about three times greater than that of the proliferating zone of the normal weanling rat and approximately four times greater in the rachitic rats. 3. Following a single dose of vitamin D (8000 I. U.) there was a significant elevation in alkaline phosphatase activity of the proliferating zone. A less significant increase was observed in the proliferating zone of rats which had breen fasted 48 hours. 4. There was a significant decrease in the alkaline phosphatase activity of the central region of hypertrophic zone of cartilage after vitamin D treatment. No such decrease was observed in the fasted rats. 5. In the normal weanling rat glucose-6-phosphate dehydrogenase (G-6-PDH) activity was greater in the proliferating zone as compared to the hypertrophic zone. In the untreated rachitic rat the enzyme content was about the same in the two zones. 6. Following vitamin D treatment there was an appreciable decrease in the G-6-PDH activity. No such decrease was observed in the fasted rat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02012535
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Pharmacological effects and serum levels of orally administered alprenolol in man (1972)
    Springer
    European journal of clinical pharmacology 5 (1972), S. 44-52 
    Details
    ISSN: 1432-1041
    Keywords: alprenolol ; serum drug level ; exercise ; man ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effects of alprenolol on heart rate and systolic blood pressure were studied in healthy subjects during standardized exercise on a bicycle ergometer. In one series of experiments, in which serum concentrations of alprenolol were also measured, the effects of single oral doses of 50, 100 and 200 mg of alprenolol and a placebo were compared by a double blind cross-over technique. In a second series of experiments 100 mg alprenolol was given four times in one day and the effect was followed for up to eighteen hours after the last dose. — Alprenolol diminished the expected increase in heart rate and systolic blood pressure during exercise. The reduction of exercise tachycardia in a given individual was linearly related to the logarithm of the dose or the serum concentration of alprenolol. The serum concentrations required for a given reduction of exercise tachycardia varied almost one hundred-fold amongst the subjects studied. The biological availability of alprenolol was dose-dependent, probably due to a limited capacity biotransformation of the drug before it entered the general circulation. After a single dose the serum level of alprenolol and its chronotropic effect diminished at a rate corresponding to an elimination half life of about two hours. This rate of elimination was consistent with that calculated from the results of the four dose study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00560895
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Absorption and excretion of pralidoxime in man after intramuscular injection of PAM-2CL and various cholinolytics (1972)
    Springer
    European journal of clinical pharmacology 5 (1972), S. 58-61 
    Details
    ISSN: 1432-1041
    Keywords: Pralidoxime chloride ; pharmacokinetics ; anti-cholinesterase poisoning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary A dose of 1.0 g (10.0–14.0 mg/kg body weight) of pralidoxime mixed with various cholinolytics was given by i.m. injection to 29 healthy male subjects. A concentration of pralidoxime in blood of 4 µg/ml was reached after 5 to 10 min with all the mixtures and was maintained for about 1 to 2 h. The calculated half lives of pralidoxime in three groups of subjects were 62.2, 60.0 and 61.8 min., respectively. — The urinary excretions of pralidoxime during the first 4 h after the injections averaged 75.0, 79.6 and 69.6 per cent, respectively, of the total amount given. — The results are compared with published information about similar oximes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00560897
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Sulphamethoxazole/trimethoprim: Pharmacokinetic studies in patients with chronic renal failure (1972)
    Springer
    European journal of clinical pharmacology 4 (1972), S. 233-240 
    Details
    ISSN: 1432-1041
    Keywords: Sulphamethoxazole ; trimethoprim ; pharmacokinetics ; uraemia ; sulphonamides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of sulphamethoxazole (SMZ) and trimethoprim (TMP) have been investigated in four healthy volunteers, 15 patients with stable chronic renal failure and 3 patients on regular dialysis. The dosage schedule was 400 mg of SMZ and 80 mg of TMP orally every 12 h. The plasma concentrations and urinary excretion have been analysed in terms of a one compartment open model, allowing for elimination by renal excretion and metabolic processes. — At equilibrium the plasma concentrations of unchanged sulphonamide showed no significant correlation with the degree of renal impairment. The accumulation of TMP increased slightly without affecting the concentration ratio of both agents in plasma. In contrast, increasing accumulation of metabolized SMZ was demonstrated in the presence of renal insufficiency. Indirect evidence indicates that rising metabolite levels under these circumstances may lead to a displacement of unchanged sulphonamide from protein binding sites. — The cumulative urinary excretion amounted to 82.4% of the dose of sulphonamide administered, which probably corresponds to the fraction of the compound absorbed. The urinary concentration of biologically active SMZ was slightly below the plasma level, especially in advanced renal failure, but it remained above the minimum inhibitory concentrations reported in the literature. The concentration of TMP in urine was considerably higher than in plasma, it decreased with loss of renal function as did active SMZ.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00635802
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Gas chromatographic determination of therapeutic levels of amobarbital and pentobarbital in plasma (1972)
    Springer
    European journal of clinical pharmacology 4 (1972), S. 191-195 
    Details
    ISSN: 1432-1041
    Keywords: Amobarbital ; pentobarbital ; barbiturates ; gas chromatography ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Gas chromatographic methods are described for the assay of amobarbital and pentobarbital in 500 µl samples of plasma, in concentrations down to 250 ng/ml. After ether extraction at pH 5.5, the barbiturates are reextracted into an alkaline solution of trimethylanilinium hydroxide and are determined quantitatively by gas chromatography as their dimethylated derivatives. The method has been used successfully in volunteers receiving therapeutic doses of these bariturates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00635794
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of fentanyl in man and the rabbit (1972)
    Springer
    European journal of clinical pharmacology 4 (1972), S. 137-141 
    Details
    ISSN: 1432-1041
    Keywords: Fentanyl ; pharmacokinetics ; neuroleptanalgesia ; analogue computer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Plasma levels and urinary excretion of3H-fentanyl were studied in 5 human subjects after intravenous injection of this drug. After an initial rapid decline, the plasma level of fentanyl decreased slowly and approximately exponentially. The plasma concentration of metabolites remained almost steady from 1–3 h after injection. More than 60% of the administered radioactivity was excreted through the kidneys within 4 days. Only a small proportion of it was unchanged fentanyl. The rates of fall of plasma concentration and of urinary excretion were slower in man than in rabbits. — The time courses of plasma concentrations and of urinary excretion were simulated on an analogue computer. The results support the assumption that the different time courses of concentrations in man and rabbits are caused by slower metabolism in man. It seems likely that redistribution plays a dominant part in the short duration of action of fentanyl in man.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00561135
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Evaluation of a micromethod for determination of antibiotic concentrations in plasma (1972)
    Springer
    European journal of clinical pharmacology 4 (1972), S. 150-157 
    Details
    ISSN: 1432-1041
    Keywords: Antibiotics ; pharmacokinetics ; microbiological assay ; drug control ; neonatal septicaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The various steps of a paper disc micromethod for quantitative determination of plasma concentrations of antibiotics is described. Only 10 µl of plasma is needed for a single determination, allowing easy and repeated capillary sampling. Separate assay was attempted of three antibiotics in a mixture (streptomycin, cloxacillin and ampicillin), both by use of selective inhibitors (semicarbazide, penicillinase) in the culture medium and by choosing suitable strains of bacteria. In this way, it was possible to determine streptomycin and cloxacillin separately when all three antibiotics were present simultaneously in the plasma. The assay of ampicillin, however, was always influenced by the presence of even small concentrations of cloxacillin. The 95% confidence intervals of the standard curves for the three antibiotics are presented. — The method is suitable both for pharmacokinetic studies and for routine clinical control of plasma antibiotic levels, even in premature children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00561138
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    II. Ultrastructure of duct cell granules in mammalian submaxillary glands (1972)
    Springer
    Cell & tissue research 126 (1972), S. 335-347 
    Details
    ISSN: 1432-0878
    Keywords: Glandulae submaxillares ; Mammals ; Duct cell granules ; Ultrastructure ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Discrete, PAS-positive granules of relatively uniform electron-density and size characterise the intercalated duct cells of mammalian submaxillary glands. Smaller, electron-dense organelles are seen in the cells at the junction of the intercalary-striated duct region in the guinea-pig. The large granules of variable electron-density which are observed in the proximal, modified intercalary cells in the rabbit closely resemble the granules in the acinar cells of the guinea-pig. Several populations of granules differing in size are found in the striated granular tubules of the rat and hamster; the organelles in the rat show two grades of electron-density whereas those in the hamster are uniformly dense. Numerous small granules with compactly arranged intragranular material occupy the apical part of the striated ducts of the cat, dog and rabbit. The chemical composition of each population of duct cell granules is unknown. The question whether granules containing kallikrein, trypsin-like enzymes and amylase are stored in the duct cells is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306848
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Histology and ultrastructure of the neurohypophysis of the south american lungfish, Lepidosiren paradoxa (1972)
    Springer
    Cell & tissue research 131 (1972), S. 47-62 
    Details
    ISSN: 1432-0878
    Keywords: Neurohypophysis ; Lungfish ; Ultrastructure ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The neurohypophysis of the South American lungfish Lepidosiren paradoxa has been studied with light and electron microscopy, including the Falck-Hillarp technique for catecholamines. The pars nervosa hypophyseos is a well-marked, dorsally located subdivision of the pituitary gland composed of lobes or follicles, each one constituted of a central core of ependymal cells, a subependymal hilar region made up of nerve fibers and a peripheric palisade zone of nerve endings which contact capillary vessels. Four types of neurosecretory axons can be distinguished under the electron microscope. Type I, the most common, contains spherical elementary granules of high electron density, 1500–1800 Å in diameter. The scarce type II axons contain irregularly-shaped elementary granules. Type III contains only small clear vesicles, 400–600 Å in diameter. Type IV, mostly present in regions of the gland contacting the pars intermedia, contain large granulated vesicles, 900–1000 Å in diameter. The Falck-Hillarp technique revealed axons with a positive reaction for catecholamines at sites corresponding approximately to the location of type IV of the electron microscope. Ependymal cells are of large size, linking the cerebrospinal fluid, the nerve endings and the blood vessels. A conspicuous membrane-bound, spherical dense material, 1400–2000 Å in diameter, is observed in both the apical and vascular processes of these cells. The ependymal processes which traverse the hilar and palisade regions contain structures resembling degenerated neurosecretory axons. These results are discussed in relation with the currently available information on the comparative anatomy of the pars nervosa. The possible functional significance of ependymal cells and of each type of axon are also discussed. This study was aided by the following grants: NIH NS 06953 to Prof. De Robertis, Consejo Nacional de Investigaciones Científicas y Técnicas to Prof. Zambrano, Comisión de Investigaciones Científicas de la Provincia de Buenos Aires and Comisión de Investigaciones Cientificas de la Universidad Nacional de la Plata: to Prof. Iturriza. The authors are indebted to Prof. De Robertis for his generosity in granting us his laboratory facilities, and to Dr. F. J. J. Risso and Mr. A. Fernández (Resistencia, Chaco) who provided the specimens used in this study. The able microtechnical assistance of Miss L. Riboldazzi and Mrs. R. Raña and the photographic work of Mr. A. Saenz are much appreciated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307200
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Effect of androgens and antiandrogens on the development of the myoid cells of the rat seminiferous tubules (organ culture) (1972)
    Springer
    Cell & tissue research 131 (1972), S. 299-308 
    Details
    ISSN: 1432-0878
    Keywords: Testis, rat ; Myoid cells ; Androgens ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary To study the regulation of the development of myoid cells, seminiferous tubules of adult and prepubertal rats were grown in organ culture under the influence of testosterone, HCG and cyproterone acetate. Contractility, EM-structure and histochemical activities of alkaline phosphatase and ATPase of the myoid cells were studied in the adult rat tubules at one week intervals up to 5 weeks in culture, in the prepubertal rat tubules at the age of 15 days and after 15 and 21 days in culture. As in vivo, contractions appear in cultured tubules of prepubertal rats at the age of 15 days. Testosterone and HCG increase the percentage of contractile tubules and the number of filaments of the myoid cells. Cyproterone acetate inhibits both functional and structural development and tends to decrease the enzyme activities. In the cultured adult rat tubules cyproterone acetate causes disappearance of contractility within one week, while contractions normally are found for 3 weeks. Testosterone and HCG have no notable effects on the contractility of adult rat tubules, but they lengthen the persistence of alkaline phosphatase activity. It is concluded that the maturation and also the functioning of the myoid cells are subject to androgenic regulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00582853
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 11
    Electronic Resource
    Electronic Resource
    Ultrastructural and histochemical studies on the innervation of the heart of a teleost, pleuronectes platessa L. (1972)
    Springer
    Cell & tissue research 131 (1972), S. 519-528 
    Details
    ISSN: 1432-0878
    Keywords: Cardiac innervation ; Teleosts ; Acetylcholinesterase ; Fine structure ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The innervation of the heart of the plaice has been studied ultrastructurally and histochemically in order to describe the anatomy, and the nature of the neuro-transmitters involved in the regulation of the heart. A single cardiac branch of the vagus runs over the Duct of Cuvier and sinus venosus where it forms a plexus extending into the sinoatrial region. Many ganglion cells are scattered throughout this plexus upon which are seen cholinergic-type terminals at which AChE can be localised. It is therefore concluded that this is the parasympathetic cardiac ganglion. The innervation of the atrium is dense at the sinoatrial end but decreases towards the ventricle. The ventricle is probably aneural, possibly a consequence of the lack of a coronary blood supply to act as a pathway for an innervation of this chamber. Most of the intramural axon profiles contain large numbers of small agranular vesicles and are cholinergic, AChE being localised at their membranes. Other profiles contain small numbers of larger granular vesicles amongst the agranular vesicles but these are not adrenergic since these vesicles are not depleted by reserpine, do not load with 6-OHDA, and AChE can be localised at the membranes of the profiles. No adrenergic-type profiles were seen in any part of the heart, nor were any fluorescent, catecholamine-containing fibres observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306968
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 12
    Electronic Resource
    Electronic Resource
    Les cellules sensorielles des papilles de la trompe chez Glycera convoluta Keferstein (Annélide Polychète) (1972)
    Springer
    Cell & tissue research 134 (1972), S. 351-366 
    Details
    ISSN: 1432-0878
    Keywords: Sensory cell ; Proboscis ; Glycera convoluta ; Papilla ; Electronmicroscopy ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Chaque papille de la trompe chez Glycera convoluta contient un groupe central de deux à quatre cellules sensorielles primaires. Chaque cellule possède un noyau allongé situé à mi-hauteur de la papille. Le processus péripherique ou dendritique porte cinq à six cils qui traversent la cuticule et sont entourés chacun par un cercle de microvillosités; les cils se prolongent dans le cytoplasme par de fines racines ciliaires qui se réunissent pour former une seule énorme racine montrant une striation périodique. Le processus central ou axonal se prolonge dans le plexus nerveux sous-épithélial. Le rôle physiologique de ces cellules est discuté.
    Notes: Summary Each papilla in the proboscis of Glycera convoluta contains a central group of two to four primary sensory cells. Each one shows an elongated nucleus situated at half-height of the papilla. The peripheric or dendritic process bears five to six cilia traversing the cuticle; each of them is circled by a ring of microvilli. The cilia are prolonged in the cytoplasm by fine ciliary rootlets which gather themselves in a very big single root showing a periodic striation. The central or axonal process runs in the subepithelial nervous plexus. The physiological role of the cells is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307171
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 13
    Electronic Resource
    Electronic Resource
    Distribution of acetyl cholinesterase in the hippocampal region of the guinea pig (1972)
    Springer
    Cell & tissue research 131 (1972), S. 481-495 
    Details
    ISSN: 1432-0878
    Keywords: Hippocampal region ; Guinea pig ; AChE distribution pattern ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. The distribution of acetyl cholinesterase (AChE) has been described in the dentate area, a part of the hippocampal region, in the adult guinea pig. The enzyme was demonstrated histochemically with a modification of the Koelle thiocholine method applied to formaldehyde-fixed frozen sections and unfixed cryostat sections. Non-specific cholinesterase was suppressed by ethopropazine, while the staining reaction for AChE was controlled by complete specific inhibition with BW 284c51. A single brain was stained according to the method of Karnovsky and Roots. 2. The abundant AChE found in the dentate area exhibited a distinctly stratified distribution pattern. In the molecular layer, strong reaction was present in the outer third and immediately above the granular cell layer, the intermediate zone being light. The granular cell bodies were unstained. In the hilus, five layers showing alternating stronger and weaker reaction for AChE were recognizable. 3. In view of the opinions of Cajal, Lorente de Nó, and Blackstad criteria for the definition of the dentate area are discussed. The present results fit into a concept of a layered guinea pig hilus representative of one group of mammals (other members being rabbit, monkey, and man) differing morphologically from the non-layered hilus of rat and mouse. The distribution of metal in the guinea pig hilus supports the concept. 4. Possible structural correlates to the AChE are considered and a comparison with the distribution of AChE in the rat, reported earlier, has been made. In the molecular layer, the most striking difference was the heavy activity observed in the outer third in the guinea pig, where the content is moderate in the rat. The granular cell layer appeared virtually identical in both species. In the hilus the stratified pattern in the guinea pig, contrasting with the more diffuse distribution in the rat, essentially reflects the differing structural architectonics in the hilus of the two species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306966
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 14
    Electronic Resource
    Electronic Resource
    Morphologische und funktionelle Befunde nach Milchsäuredauerinfusion in das Jejunum der Ratte (1972)
    Springer
    Cell & tissue research 132 (1972), S. 107-129 
    Details
    ISSN: 1432-0878
    Keywords: Jejunum (rat) ; Lactic acid perfusion ; Mucosal hypertrophy ; Histology ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung An weiblichen Wistarratten wurden die zellulären und strukturellen Veränderungen der Dünndarmschleimhaut nach chronischer MS-Belastung durch 12tägige Dauerinfusion ins Jejunum untersucht. Folgende Befunde wurden erhoben: 1. Die MS-Belastung führt in Abhängigkeit von der Konzentration zur Reduktion des Glukosetransports. 2. Die Funktionsstörung ist bedingt durch Enzymaktivitätsverlust. 3. Die Reduktion betrifft alle enzymhistochemisch untersuchten Aktivitäten; sie zeigt, daß alle Zellkompartimente des Epithels beeinträchtigt sind. 4. Qualitative Abweichungen des Reaktionsmusters treten nach MS-Belastung nur beim Saure-Phosphatase-Nachweis auf. Sie sind gekennzeichnet durch Schwund der Markierbarkeit lysosomaler Granula und Auftreten einer schwachen, diffusen cytoplasmatischen Aktivität. 5. Die Schleimhaut unterliegt einer von der MS-Konzentration abhängigen Transformation mit Verschiebung der Zottenhöhen und Kryptentiefen. Sie wird begleitet von einer gesteigerten mitotischen Aktivität als Folge erhöhter Zellexfoliation an der Zottenspitze. Es handelt sich bei dieser Veränderung somit um eine Schleimhauttransformation vom hyper-regeneratorischen Typ. Ihr Initialstadium ist eine Hypertrophie, ihr Endstadium die zottenlose Schleimhaut mit stark veränderten Krypten. Das Endstadium wird unter MS-Belastung nicht ausgebildet, da geringe Konzentrationssteigerungen zu lokaler Gewebsschädigung und Darmperforation führen. 6. Das MS-Modell ist wegen seiner geringen experimentellen Breite ungeeignet für die biochemische Nacharbeitung der bei der einheimischen Sprue beobachteten cytochemischen Epithelveränderungen.
    Notes: Summary Cellular alterations and mucosal changes in zonation of the small intestine have been studied after prolonged perfusion (12 days) with lactic acid in the rat. These investigations were carried out with cytochemical methods using marker enzymes to study in detail the different stages of mucosal transformation of the hyperregenerative type. Results. 1. Lactic acid produces a dose-dependent reduction in glucose absorption and this is due to alterations of the absorptive epithelium. 2. The normal zonation of the small intestinal mucosa is changed. The degree and pattern of the alterations is dose-dependent. Mucosal hypertrophy—i.e. increase of villus height, crypt length and mitotic activity—is the initial stage of this process. 3. Both, cellular alterations and mucosal changes in zonation are the expression of strong compensatory activities in response to predominantly intraluminal stress. The relationship between mucosal hypertrophy after intestinal resection and mucosal transformation of the hyperregenerative type as induced by lactic acid infusion is discussed. 4. In view of its very limited experimental range the lactic acid model cannot be recommended for the study of the epithelial changes in mucosal transformation at a biochemical level.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00310300
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 15
    Electronic Resource
    Electronic Resource
    On the histology and histochemistry of the snout and vibrissae of the common shrew (Sorex araneus L.) (1972)
    Springer
    Cell & tissue research 124 (1972), S. 445-453 
    Details
    ISSN: 1432-0878
    Keywords: Tactile hair system ; Snout ; Shrew ; Histology ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The structure of the snout and tactile hair system of the common shrew (Sorex araneus) and the distribution of cholinesterase and alkaline phosphatase activity were studied. The structure of the vibrissae is exceptional compared with that of other mammals studied. Differences are the attachment system of hair follicle to the capsule, the impossibility of dividing the blood sinus clearly into cavernous sinus and ring sinus, the lack of continuous ring-wulst, clear constriction in the outer root sheath at the neck of hair follicle and some specialized structures connected with this. Alkaline phosphatase was not found in the nervous structures of the vibrissae but cholinesterase activity occurs at least in two different structures upon or in the outer root sheath of the hair follicle. The role of these structures and the significance of vibrissae to the shrew is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00335250
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 16
    Electronic Resource
    Electronic Resource
    Long-term cell culture of two differentiated cell types from the liver of larval and adult Xenopus laevis (1972)
    Springer
    Cell & tissue research 128 (1972), S. 457-469 
    Details
    ISSN: 1432-0878
    Keywords: Liver ; Amphibian ; Tissue culture ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Two distinct types of cells were derived from organ cultures of liver from adult and larval Xenopus laevis. Each type was isolated in clonal cell culture. Several media were compared with respect to support of epithelioid outgrowths from explants and support of growth of epithelioid colonies in cell culture. Ultracentrifuged embryo extract promotes the growth of all cell types, but the particulate fraction is also required for the maintenance of the epithelioid morphology of larval cells. In these media it was possible to maintain some epithelioid cell cultures for over 6 months. The identity and retention of some specialized functions of both cell types were demonstrated on larval cells. One cell type contained PAS-stainable, amylase-sensitive granules that increased in amount after treatment with glucocorticoids. This same type was shown by histochemical methods to contain phosphorylase, glucose-6-phosphatase, and dexamethasone-inducible tyrosine aminotransferase, and is considered to be a hepatocyte. The second type appears to be a sinusoidal cell, since it phagocytosed trypan blue and stained positively for acid phosphatase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306982
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 17
    Electronic Resource
    Electronic Resource
    Histochemistry and Ultrastructure of the Epidermis and the Subepidermal Gland Cells of the Freshwater Snails Lymnaea stagnalis and Biomphalaria pfeifferi (1972)
    Springer
    Cell & tissue research 130 (1972), S. 93-134 
    Details
    ISSN: 1432-0878
    Keywords: Epidermis ; Snails (Lymnaea stagnalis, Biomphalaria pfeifferi) ; Histochemistry ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The epidermis and the associated subepidermal gland cells of the freshwater snails Lymnaea stagnalis and Biomphalaria pfeifferi were studied by means of histochemical and electron microscope techniques. The single cell layered epidermis is composed of general epidermal cells, cilia cells and a few scattered goblet cells. The foot sole and the epidermal regions of the pneumostome and the ventral surface of the lips near the mouth consist nearly entirely of cilia cells; elsewhere the cilia cells are found scattered among the general epidermal cells. The apical layer of the general epidermal cells bear microvilli. Numerous mitochondria, vesicles and lysosomes are located in the apical region of the cells. Several Golgi bodies and a poorly developed granular endoplasmic reticulum occur in the supranuclear region; the nucleus lies in the basal part of the cell. The general epidermal cells in the mouth region contain numerous microfilaments compared to the general epidermal cells in the rest of the epidermis. The cilia of the cilia cells in the densely ciliated regions possess well developed roots and basal bodies interconnected by means of the basal feet. With regard to the other cell organelles, cilia cells are quite similar to the general epidermal cells. For comparison a brief study of the ultrastructure of the epidermis of the terrestrial snail Helix aspersa was carried out. The skin of the snail is covered by a mucous layer produced by various gland cells. In L. stagnalis, in addition to the epidermal goblet cells, thirteen subepidermal gland cell types could be distinguished. The histochemistry of the gland cell types is reflected in the ultrastructure. Three of the gland cell types have an ubiquitous distribution, four types are peculiar to the foot, two types to the lips and five types to the mantle. In B. pfeifferi one epidermal gland cell type and only seven subepidermal gland cell types could be distinguished. Most of these gland cells are limited in their distribution to the foot, lips and mantle edge. The observations may provide a basis for further study in the functions of the snail epidermis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306996
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 18
    Electronic Resource
    Electronic Resource
    Les glandes exocrines des termites (1972)
    Springer
    Cell & tissue research 130 (1972), S. 205-218 
    Details
    ISSN: 1432-0878
    Keywords: Sternal gland ; Trinervitermes geminatus ; Cell types ; Histochemistry ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé La glande sternale de Trinervitermes geminatus correspond à un épaississement médian de la partie antérieure du cinquième sternite abdominal. Elle est bordée intérieurement par une fine basale conjonctive et extérieurement par la cuticule, quelques sensilles campaniformes sont également visibles dans la masse glandulaire. On peut y reconnaître deux types de cellules: d'abord des cellules ovalaires situées dans la partie moyenne de la glande. Elles contiennent de grosses mitochondries et des globules denses, et sont en relation avec la basale par quelques fins prolongements cellulaires. Ensuite des cellules cylindriques, bien développées, constituant toute l'épaisseur de la glande. Elles possèdent de nombreuses vésicules de reticulum lisse et une bordure en brosse formée de microvillosités et de digitations cytoplasmiques qui pénètrent dans la cuticule. Cette cuticule comprend une mésocuticule lacunaire et une fine épicuticule percée par des «canalicules épicuticulaires». Une comparaison est établie avec la glande sternale d'autres termites, en particulier celle de Kalotermes.
    Notes: Summary The sternal gland of Trinervitermes geminatus appears as a median thickening of the epidermis at the anterior part of the fifth abdominal sternite. It is lined internally with a thin basal lamina and externally with the cuticle. A few campaniform sensilla are also visible in the glandular mass. Two types of cells may be recognized. First, oval-shaped cells, containing numerous large mitochondria and dense globules; these cells having no contact with the cuticle are connected with the basal lamina by a few narrow cytoplasmic stems. Second, tall columnar cells, with vesicular endoplasmic reticulum and an apical brush border built up by microvilli and finger—like processes which reach into the cuticle. This cuticle is made of alveolous mesocuticle and a thin epicuticle perforated by “epicuticular canals”. The organ is compared with the sternal gland of other termites, particularly with the one of Kalotermes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306958
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 19
    Electronic Resource
    Electronic Resource
    On the harderian gland of the domestic duck (Anas platyrhynchus) (1972)
    Springer
    Cell & tissue research 133 (1972), S. 223-230 
    Details
    ISSN: 1432-0878
    Keywords: Harderian gland ; Anas platyrhynchus ; Polysaccharides ; Histology ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The parenchyma of the Harderian gland of the domestic duck consists of numerous tubular terminal portions, lined by a simple columnar epithelium. Its secretory surface is increased by intratubular folds. Within the cytoplasm of the epithelial cells secretory granules are observed. Polysaccharides of different nature are demonstrated. Strikingly, all centrally located cells contain a periodate reactive mucin. The successive administration of the PAS reaction and of Alcian Blue reveals the coexistence of acid and neutral mucins in the same cells. A metachromatic reaction of the mucosubstances at pH 1.0 was observed and the presence of acid sulfated groups in the Harderian gland, as demonstrated byAlcian Blue at pH 0.5, thereby confirmed. There was no glycogen reaction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307144
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 20
    Electronic Resource
    Electronic Resource
    Über den Peroxydasetransport im Darmepithel der Ratte (1972)
    Springer
    Cell & tissue research 134 (1972), S. 403-410 
    Details
    ISSN: 1432-0878
    Keywords: Small intestine (rat) ; Transport of peroxidase ; Epithelium ; Histochemistry ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Bei Ratten tritt 3 min nach intravenöser Injektion von Peroxydase elektronenmikroskopisch ein entsprechendes Reaktionsprodukt im Kapillarlumen der Lamina propria des Dünndarms und an der Basalmembrangrenze der Saumepithelzellen auf. 5 min nach der Injektion finden sich im basalen Abschnitt des Darmepithels pinozytotische Bläschen mit dem Peroxydase-Reaktionsprodukt. — 10–30 min nach der Injektion erreichen die Partikel die apikalen Teile der Zelle. Sie dringen in den interzellulären Spalten bis zu den Haftplatten vor, erreichen jedoch nie das Darmlumen. Im Dünndarm existiert vermutlich auch ein der Resorption entgegengesetzter Saftstrom, der durch Peroxydase markiert werden kann.
    Notes: Summary In rats, 3 minutes after intravenous injection of peroxidase the reaction product can be observed electronmicroscopically in the lumina of the capillaries of the small intestine as well as at the border of the basement membrane of the epithelial border cells. Pinocytotic vesicles containing peroxidase particles occur in the basal portion of the epithelium of the small intestine 5 minutes after injection. 10–30 minutes later, the peroxidase reaches the apical region of the cell. The particles infiltrate into the intercellular spaces as far as the tight junctions but never reach the intestinal lumen. In the small intestine there probably exists a flow of fluid in opposite direction to the resorption, which can be marked by peroxidase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307174
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 21
    Electronic Resource
    Electronic Resource
    Axoplasmic flow of adrenaline and monoamine oxidase in amphibian sympathetic nerves (1972)
    Springer
    Cell & tissue research 124 (1972), S. 44-56 
    Details
    ISSN: 1432-0878
    Keywords: Axonal transport ; Toad spinal nerves ; Ligation ; Sympathectomy ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The accumulation of both A and MAO proximal to a ligature on toad spinal nerves has been shown to occur at a slower rate than in mammals. As in mammals, there are two components of axonal transport in amphibian nerves, with the accumulation of A reaching a peak at between 4 and 7 days (cf. 2–4 days for NA in mammals), while MAO accumulation does not reach its maximum before 9 days (cf. 7 days in mammals). No accumulation occurs after sympathectomy, providing evidence for localization of MAO within amphibian sympathetic adrenergic nerves. Distal accumulation of MAO occurs in toad sympathetic nerves; this has not been reported to occur in mammalian nerves. Distal accumulation reaches a peak at 2–4 days, which suggests either a fast retrograde flow of MAO or that induction of MAO is occurring. These results are discussed in relation to differences between mammalian and amphibian sympathetic nerves and to the events occurring following ligation of these nerves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00335453
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 22
    Electronic Resource
    Electronic Resource
    Studies on the cytophysiology of the fat body of the American silkmoth (1972)
    Springer
    Cell & tissue research 124 (1972), S. 433-444 
    Details
    ISSN: 1432-0878
    Keywords: Insect ; Fat body ; Development ; Protein body ; Electron microscopy ; Histochemistry ; Lipoprotein ; Cytology ; Lipid globule ; Silkworm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A developmental study at the electron microscopic level was conducted of the fat body cells of Hyalophora cecropia (L.). During the last larval instar the fat body increases in volume and the cells exhibit a well developed rough endoplasmic reticulum and protein bodies of diverse sizes. In the pupal fat body, the protein bodies appear to be enclosed by a double membrane and contain glycogen granules, ribosomes and mitochondrion-like structures. In addition, there are large lipid globules, cytolysomes and rough endoplasmic reticulum. The ultrastructure of the protein bodies suggests the development of large bodies by fusion of smaller protein bodies. Changes in fat body cell ultrastructure were followed during adult development and cytological evidence was obtained for the depletion of protein, glycogen and lipid in the female during this period. The female adult fat body cell contains free ribosomes, protein bodies, many mitochondria, a few lipid globules and glycogen granules. The male moth fat body cells have many mitochondria, a few glycogen granules, essentially no protein bodies, but an abundance of large lipid globules. Studies on the influence of egg maturation on the morphology of the fat body of Hyalophora gloveri (L.) revealed that ovariectomy of pupae yielded adults having more fat body than normal females, and that the fat body cells of the ovariectomized animals contained more glycogen, lipid and protein. Male pupae receiving ovarian implants developed into adults containing eggs and possessed more fat body than normal females but less than normal males. Very few glycogen granules were found in the fat body cells of normal males or males with implanted ovaries.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00335249
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 23
    Electronic Resource
    Electronic Resource
    I. Ultrastructure of acinar cell granules in mammalian submaxillary glands (1972)
    Springer
    Cell & tissue research 126 (1972), S. 320-334 
    Details
    ISSN: 1432-0878
    Keywords: Glandulae submaxillares ; Mammals ; Acinar cell granules ; Ultrastructure ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Granules in acinar cells show considerable variations in size, shape, electron-density and molecular organisation of secretory material. Discrete organelles with an electron-dense homogenous matrix are seen in the guinea-pig and to some extent in the male hamster. Similar organelles with moderate electron-density are seen in the cat and dog. Acinar cells of the cat, hamster, guinea-pig and to a lesser extent the rat, contain discrete, pale granules and also confluent organelles arising from two to three of the pale particles. Composite, electron-pale secretory units are observed in the dog and rabbit. No correlation could be elicited between the histochemical reactivity of the acinar cells and the content of the secretory enzymes. The relationship between the histochemical reactivity and ultrastructural appearance of acinar cell granules and the organelles containing kallikrein, trypsin-like proteases and amylase seems much more important and functionally relevant. Morphological aspects of the intracellular transport and secretion of granules are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306847
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 24
    Electronic Resource
    Electronic Resource
    Axoplasmic flow of adrenaline and monoamine oxidase in amphibian sympathetic nerves (1972)
    Springer
    Cell & tissue research 124 (1972), S. 44-56 
    Details
    ISSN: 1432-0878
    Keywords: Axonal transport ; Toad spinal nerves ; Ligation ; Sympathectomy ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The accumulation of both A and MAO proximal to a ligature on toad spinal nerves has been shown to occur at a slower rate than in mammals. As in mammals, there are two components of axonal transport in amphibian nerves, with the accumulation of A reaching a peak at between 4 and 7 days (cf. 2–4 days for NA in mammals), while MAO accumulation does not reach its maximum before 9 days (cf. 7 days in mammals). No accumulation occurs after sympathectomy, providing evidence for localization of MAO within amphibian sympathetic adrenergic nerves. Distal accumulation of MAO occurs in toad sympathetic nerves; this has not been reported to occur in mammalian nerves. Distal accumulation reaches a peak at 2–4 days, which suggests either a fast retrograde flow of MAO or that induction of MAO is occurring. These results are discussed in relation to differences between mammalian and amphibian sympathetic nerves and to the events occurring following ligation of these nerves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00981940
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 25
    Electronic Resource
    Electronic Resource
    La structure fine des caecums rectaux de deux Asteriidae: Marthasterias glacialis (L) et Coscinasterias tenuispina (Lam) (Echinodermata, Asteroidea) (1972)
    Springer
    Cell & tissue research 128 (1972), S. 366-384 
    Details
    ISSN: 1432-0878
    Keywords: Rectal caeca ; Starfishes ; Epithelium ; Histochemistry ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Dans les caecums rectaux des deux espèces étudiées, stratification tissulaire et composition cellulaire sont semblables. L'épithélium interne se compose de mucocytes et de cellules banales. Outre du glycogène, ces dernières renferment chez M. glacialis des grains de mucopolysaccharides neutres associés à des protéines tandis que chez C. tenuispina, les granules contiennent des mucopolysaccharides acides carboxylés et sulfatés également associés à des protéines. L'épithélium externe de C. tenuispina présente, outre des cellules banales, des cellules glandulaires à contenu protéique. Une attention particulière a été apportée à l'ultrastructure du pôle apical des cellules banales internes. On y remarque de nombreuses microvillosités et un flagelle central caractéristique. De plus, on observe très fréquemment des formations pinocytaires ainsi que plus rarement de la phagocytose. Les diverticules seraient donc, chez les Asteriidae, des organes digestifs à part entière se caractérisant par un grand pouvoir d'absorption et une digestion intracellulaire. Enfin, le pôle basal des cellules banales internes, très contourné, contient, par endroit, des β-cytomembranes typiques. Il est possible qu'à ce niveau aient lieu des transferts de substances vers le coelome.
    Notes: Summary Histological and cytological composition are similar in the rectal caeca of both studied species. Internal epithelium is composed of mucocytes and of banal cells. Besides glycogen, these cells contain in M. glacialis neutral mucopolysaccharides associated with proteins, while in C. tenuispina, the granules contain acidic carboxyled and sulfated mucopolysaccharides also associated with proteins. The external epithelium of C. tenuispina presents, besides banal cells, granular secretory cells with proteic content. Special attention has been payed to the ultrastructure of the apical pole of the internal banal cells. One notices numerous microvilli and a characteristic central flagellum. Moreover, one frequently observes pinocytic formations as well as—more rarely—phagocytosis. The rectal diverticula would thus be, in the Asteriidae, real digestive organs provided with a great capacity of absorption and intracellular digestion. The basal pole of the internal banal cells contains from place to place typical β-cytomembranes. Transfers of substances to the coelom can occur at that level.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306976
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 26
    Electronic Resource
    Electronic Resource
    Experimentelle studien über den Myofer®-Transport durch das Pansenepithel der Ziege (1972)
    Springer
    Cell & tissue research 129 (1972), S. 561-569 
    Details
    ISSN: 1432-0878
    Keywords: Rumen epithelium (Goat) ; Permeability ; Transport of Myofer ; Histochemistry ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Durch submuköse Injektion von Myofer, einer licht- und elektronenmikroskopisch nachweisbaren Testsubstanz, wurde in vivo die Permeabilität des Pansenepithels untersucht. Folgende Befunde wurden erhoben: 1. Kurz nach der Applikation ist Myofer in allen Schichten des Epithels nachweisbar. Der Transport dieser Substanz ins Stratum corneum wird durch die tiefen Hornzellen der Barriere nicht verhindert. 2. In allen Epithelschichten ist das Myofer in Form intrazellulärer Cytosomen anzutreffen. 3. In den Interzellularräumen sind Myofergranula zwischen Basalmembran und den tiefen Hornzellen nur vereinzelt, zahlreicher jedoch jenseits der Barriere zu beobachten. Es wird gefolgert, daß die Testsubstanz Myofer die epitheliale Barriere durch transzelluläre Passage überwindet.
    Notes: Summary The permeability of the rumen epithelium to Myofer, a marker injected submucously in vivo, was studied in the light and electron microscopes. The following observations were made: 1. Myofer penetrates the ruminal epithelium 10 min after injection and can be found in all epithelial layers. The deep horny cells of the barrier layer do not prevent the penetration by this marker of the stratum corneum. 2. Myofer is present as cytosomes in cells of all epithelial layers. 3. The intercellular spaces between the basal lamina and the deep horny cells contain only few Myofer granules; the granules are more numerous on the other side of the barrier layer. The observations suggest that the marker Myofer passes through the epithelial barrier of the ruminal wall by transcellular passage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00316750
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 27
    Electronic Resource
    Electronic Resource
    Adenosine triphosphatase activity in the carotid body of the cat (1972)
    Springer
    Cell & tissue research 130 (1972), S. 455-462 
    Details
    ISSN: 1432-0878
    Keywords: Carotid body ; Cat ; ATPase ; Histochemistry ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Three kinds of nucleoside phosphatases were demonstrated histochemically in the cat carotid body with nucleoside triphosphate, nucleoside disphosphate and nucleoside monophosphate as substrates. Each of these enzyme activities exhibited the substrate specificity respectively. The nucleoside triphosphatase activity showed specific localization in association with the parenchymal cells of the carotid body. The electronmicroscopy revealed that the reaction product was located on and between the two apposing plasma membranes of type I and type II cells, of a type II cell and its wrapping axons and of the intricate basal infolding of a type II cell itself. Some possible functions of the adenosine triphosphatase in the carotid body are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306999
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 28
    Electronic Resource
    Electronic Resource
    Les cellules à calcium du conjonctif de Ferrissia wautieri (Moll. Ancylidae) (1972)
    Springer
    Cell & tissue research 134 (1972), S. 227-243 
    Details
    ISSN: 1432-0878
    Keywords: Calcium cells ; Mollusca (Ferrissia wautieri) ; Histochemistry ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Le calcium s'accumule dans les tissues de Ferrissia wautieri sous forme de sphérules de calcaire intracellulaires. Notre travail comporte une étude descriptive de ces cellules en microscopie optique et électronique, et une étude minéralogique abordée par des techniques de coloration, de dissolution, de polarisation de la lumière et de diffraction électronique. Les résultats obtenus montrent que les sphérules, par leur aspect, leur nombre, leur volume et leur état de cristallisation, présentent des caractères différents selon la saison, ce qui permet d'établir une relation entre l'état des nodules calcaires et les variations du métabolisme des individus.
    Notes: Summary In Ferrissia wautieri calcium is stored in the connective tissue in intracellular calcareous spherules. The cells have been studied light- and electronmicroscopically and a mineralogical analysis of the spherules was done by selective staining, dissolution, polarisation and electron diffraction. The results of these studies show that the aspect, the number, the volume and the rate of cristallisation of the calcospherites are different according to the seasons. Therefore it may be assumed that the characteristics of the spherules are connected with metabolic variations in these animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307155
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...