Publikationsdatum:
2012-03-10
Beschreibung:
Nanoinformatics has recently emerged to address the need of computing applications at the nano level. In this regard, the authors have participated in various initiatives to identify its concepts, foundations and challenges. While nanomaterials open up the possibility for developing new devices in many industrial and scientific areas, they also offer breakthrough perspectives for the prevention, diagnosis and treatment of diseases. In this paper, we analyze the different aspects of nanoinformatics and suggest five research topics to help catalyze new research and development in the area, particularly focused on nanomedicine. We also encompass the use of informatics to further the biological and clinical applications of basic research in nanoscience and nanotechnology, and the related concept of an extended “nanotype” to coalesce information related to nanoparticles. We suggest how nanoinformatics could accelerate developments in nanomedicine, similarly to what happened with the Human Genome and other -omics projects, on issues like exchanging modeling and simulation methods and tools, linking toxicity information to clinical and personal databases or developing new approaches for scientific ontologies, among many others. Content Type Journal Article Pages 1-19 DOI 10.1007/s00607-012-0191-2 Authors Victor Maojo, Biomedical Informatics Group, Departamento de Inteligencia Artificial, Faculdad de Informática, Universidad Politécnica de Madrid, Boadilla del Monte, 28660 Madrid, Spain Martin Fritts, SAIC-Frederick Inc., National Cancer Institute at Frederick, Frederick, MD, USA Fernando Martin-Sanchez, Health and Biomedical Informatics Research Laboratory Medical School-IBES, The University of Melbourne, Parkville, VIC, Australia Diana De la Iglesia, Biomedical Informatics Group, Departamento de Inteligencia Artificial, Faculdad de Informática, Universidad Politécnica de Madrid, Boadilla del Monte, 28660 Madrid, Spain Raul E. Cachau, Advanced Biomedical Computing Center, National Cancer Institute, SAIC-Frederick Inc., Frederick, MD, USA Miguel Garcia-Remesal, Biomedical Informatics Group, Departamento de Inteligencia Artificial, Faculdad de Informática, Universidad Politécnica de Madrid, Boadilla del Monte, 28660 Madrid, Spain Jose Crespo, Biomedical Informatics Group, Departamento de Inteligencia Artificial, Faculdad de Informática, Universidad Politécnica de Madrid, Boadilla del Monte, 28660 Madrid, Spain Joyce A. Mitchell, Biomedical Informatics Department, University of Utah, Salt Lake City, Utah, USA Alberto Anguita, Biomedical Informatics Group, Departamento de Inteligencia Artificial, Faculdad de Informática, Universidad Politécnica de Madrid, Boadilla del Monte, 28660 Madrid, Spain Nathan Baker, Pacific Northwest National Laboratory, Richland, WA, USA Jose Maria Barreiro, Biomedical Informatics Group, Departamento de Inteligencia Artificial, Faculdad de Informática, Universidad Politécnica de Madrid, Boadilla del Monte, 28660 Madrid, Spain Sonia E. Benitez, Department of Medical Informatics, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina Guillermo De la Calle, Biomedical Informatics Group, Departamento de Inteligencia Artificial, Faculdad de Informática, Universidad Politécnica de Madrid, Boadilla del Monte, 28660 Madrid, Spain Julio C. Facelli, Biomedical Informatics Department, University of Utah, Salt Lake City, Utah, USA Peter Ghazal, Division of Pathway Medicine and Centre for Systems Biology Edinburgh, University of Edinburgh, Edinburgh, UK Antoine Geissbuhler, Division of Medical Informatics, University Hospitals of Geneva, Geneva, Switzerland Fernando Gonzalez-Nilo, Center for Bioinformatics and Molecular Simulation, Universidad de Talca, Talca, Chile Norbert Graf, Department of Pediatric Oncology and Hematology, University of the Saarland, Homburg, Germany Pierre Grangeat, Laboratoire d’Electronique et de Technologie de l’Information (LETI), MINATEC Campus, Commissariat à l’Energie Atomique et aux Energies Alternatives (CEA), Grenoble, France Isabel Hermosilla, Department of Medical Bioinformatics, Institute of Health “Carlos III”, Madrid, Spain Rada Hussein, Information Technology Institute, Ministry of Communications and Information Technology, Cairo, Egypt Josipa Kern, Department of Medical Statistics, Epidemiology and Medical Informatics, Andrija Stampar School of Public Health, Zagreb University Medical School, Zagreb, Croatia Sabine Koch, Health Informatics Centre, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden Yannick Legre, Health Grid Organization, Clermont-Ferrand, France Victoria Lopez-Alonso, Department of Medical Bioinformatics, Institute of Health “Carlos III”, Madrid, Spain Guillermo Lopez-Campos, Department of Medical Bioinformatics, Institute of Health “Carlos III”, Madrid, Spain Luciano Milanesi, Institute of Biomedical Technology, National Research Council, Milan, Italy Vassilis Moustakis, Technical University of Crete, Chania, Crete, Greece Cristian Munteanu, Department of Information and Communication Technologies, University of A Coruña, A Coruña, Spain Paula Otero, Department of Medical Informatics, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina Alejandro Pazos, Department of Information and Communication Technologies, University of A Coruña, A Coruña, Spain David Perez-Rey, Biomedical Informatics Group, Departamento de Inteligencia Artificial, Faculdad de Informática, Universidad Politécnica de Madrid, Boadilla del Monte, 28660 Madrid, Spain George Potamias, Institute of Computer Science, FORTH, Heraklion, Crete, Greece Ferran Sanz, Biomedical Informatics Research Programme (GRIB), IMIM, Universitat Pompeu Fabra, Barcelona, Spain Casimir Kulikowski, Department of Computer Science, Rutgers, The State University of New Jersey, Newark, USA Journal Computing Online ISSN 1436-5057 Print ISSN 0010-485X
Print ISSN:
0010-485X
Digitale ISSN:
1436-5057
Thema:
Informatik
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